Items where Community is "Wigler lab"

Paper

Swamynathan, Manojit M, Kuang, Shan, Watrud, Kaitlin E, Doherty, Mary R, Gineste, Charlotte, Mathew, Grinu, Gong, Grace Q, Cox, Hilary, Cheng, Eileen, Reiss, David, Kendall, Jude, Ghosh, Diya, Reczek, Colleen R, Zhao, Xiang, Herzka, Tali, Špokaitė, Saulė, Dessus, Antoine N, Kim, Seung Tea, Klingbeil, Olaf, Liu, Juan, Nowak, Dawid G, Alsudani, Habeeb, Wee, Tse-Luen, Park, Youngkyu, Minicozzi, Francesca, Rivera, Keith, Almeida, Ana S, Chang, Kenneth, Chakrabarty, Ram P, Wilkinson, John E, Gimotty, Phyllis A, Diermeier, Sarah D, Egeblad, Mikala, Vakoc, Christopher R, Locasale, Jason W, Chandel, Navdeep S, Janowitz, Tobias, Hicks, James B, Wigler, Michael, Pappin, Darryl J, Williams, Roger L, Cifani, Paolo, Tuveson, David A, Laporte, Jocelyn, Trotman, Lloyd C (October 2024) Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function. Science, 386 (6720). eadk9167. ISSN 0036-8075

Mai, Nicholas, Dos Anjos, Carlos H, Razavi, Pedram, Safonov, Anton, Patil, Sujata, Chen, Yuan, Drago, Joshua Z, Modi, Shanu, Bromberg, Jacqueline F, Dang, Chau T, Liu, Dazhi, Norton, Larry, Robson, Mark, Chandarlapaty, Sarat, Jhaveri, Komal (May 2024) Predictors of Response to CDK4/6i Retrial After Prior CDK4/6i Failure in ER+ Metastatic Breast Cancer. Res Sq.

Homer, Joshua A, Koelln, Rebecca A, Barrow, Andrew S, Gialelis, Timothy L, Boiarska, Zlata, Steinohrt, Nikita S, Lee, Erinna F, Yang, Wen-Hsuan, Johnson, Robert M, Chung, Taemoon, Habowski, Amber N, Vishwakarma, Dharmendra S, Bhunia, Debmalya, Avanzi, Charlotte, Moorhouse, Adam D, Jackson, Mary, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Fairlie, W Douglas, Haider, Shozeb M, Steinmetz, Michel O, Prota, Andrea E, Moses, John E (March 2024) Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chemical Science, 15 (11). pp. 3879-3892. ISSN 2041-6520 (Public Dataset)

Comen, Elizabeth, Budhu, Sadna, Elhanati, Yuval, Page, David, Rasalan-Ho, Teresa, Ritter, Erika, Wong, Phillip, Plitas, George, Patil, Sujata, Brogi, Edi, Jochelson, Maxine, Bryce, Yolanda, Solomon, Stephen B, Norton, Larry, Merghoub, Taha, McArthur, Heather L (February 2024) Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer. iScience, 27 (2). p. 108880. ISSN 2589-0042

Ren, Zuen, Dharmaratne, Malindrie, Liang, Huizhi, Benard, Outhiriaradjou, Morales-Gallego, Miriam, Suyama, Kimita, Kumar, Viney, Fard, Atefeh Taherian, Kulkarni, Ameya S, Prystowsky, Michael, Mar, Jessica C, Norton, Larry, Hazan, Rachel B (January 2024) Redox signalling regulates breast cancer metastasis via phenotypic and metabolic reprogramming due to p63 activation by HIF1α. British Journal of Cancer. ISSN 0007-0920 (Public Dataset)

Elkin, Rena, Oh, Jung Hun, Dela Cruz, Filemon, Norton, Larry, Deasy, Joseph O, Kung, Andrew L, Tannenbaum, Allen R (January 2024) Dynamic network curvature analysis of gene expression reveals novel potential therapeutic targets in sarcoma. Scientific Reports, 14 (1). p. 488. ISSN 2045-2322 (Public Dataset)

Swamynathan, Manojit, Mathew, Grinu, Aziz, Andrei, Gordon, Chris, Hillowe, Andrew, Wang, Hehe, Jhaveri, Aashna, Kendall, Jude, Cox, Hilary, Giarrizzo, Michael, Azabdaftari, Gissou, Rizzo, Robert C, Diermeier, Sarah D, Ojima, Iwao, Bialkowska, Agnieszka B, Kaczocha, Martin, Trotman, Lloyd C (2024) FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate Cancer. Cancers, 16 (1). p. 60. ISSN 2072-6694

Simhal, Anish K, Maclachlan, Kylee H, Elkin, Rena, Zhu, Jiening, Norton, Larry, Deasy, Joseph O, Oh, Jung Hun, Usmani, Saad Z, Tannenbaum, Allen (November 2023) Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival. Blood Cancer Journal, 13 (1). p. 175. ISSN 2044-5385

Grabenstetter, Anne, Brogi, Edi, Thompson, Donna M, Blinder, Victoria S, Norton, Larry, Morrow, Monica, Robson, Mark E, Wen, Hannah Y (September 2023) Impact of reactive changes on multigene testing: histopathologic analysis of low-grade breast cancers with high-risk 21-gene recurrence scores. Breast Cancer Research and Treatment. ISSN 0167-6806

Zhu, Jiening, Oh, Jung Hun, Simhal, Anish K, Elkin, Rena, Norton, Larry, Deasy, Joseph O, Tannenbaum, Allen (September 2023) Geometric graph neural networks on multi-omics data to predict cancer survival outcomes. Computers in Biology and Medicine, 163. p. 107117. ISSN 0010-4825

Fenton, André A, Hurtado, José R, Broek, Jantine AC, Park, EunHye, Mishra, Bud (August 2023) Do Place Cells Dream of Deceptive Moves in a Signaling Game? Neuroscience, 529. pp. 129-147. ISSN 0306-4522

Franch-Expósito, Sebastià, Mehine, Miika, Ptashkin, Ryan N, Bolton, Kelly L, Bandlamudi, Chaitanya, Srinivasan, Preethi, Zhang, Linda, Goodell, Margaret A, Gedvilaite, Erika, Menghrajani, Kamal, Sánchez-Vela, Pablo, Mandelker, Diana, Comen, Elizabeth, Norton, Larry, Benayed, Ryma, Gao, Teng, Papaemmanuil, Elli, Taylor, Barry, Levine, Ross, Offit, Kenneth, Stadler, Zsofia, Berger, Michael F, Zehir, Ahmet (August 2023) Associations Between Cancer Predisposition Mutations and Clonal Hematopoiesis in Patients With Solid Tumors. JCO Precision Oncology, 7 (7). e2300070. ISSN 2473-4284

Wan, Ledong, Lin, Kuan-Ting, Rahman, Mohammad Alinoor, Ishigami, Yuma, Wang, Zhikai, Jensen, Mads A, Wilkinson, John E, Park, Youngkyu, Tuveson, David A, Krainer, Adrian R (July 2023) Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer. Cancer Discovery, 13 (7). pp. 1678-1695. ISSN 2159-8274 (Public Dataset)

Daye, Dania, Panagides, John, Norton, Larry, Ahmed, Muneeb, Fukuma, Eisuke, Ward, Robert C, Gomez, Daniel, Kokabi, Nima, Vogl, Thomas, Abi-Jaoudeh, Nadine, Deipolyi, Amy (July 2023) New Frontiers in the Role of Locoregional Therapies in Breast Cancer: Proceedings from the Society of Interventional Radiology Foundation Research Consensus Panel. Journal of Vascular and Interventional Radiology. S1051-0443(23)00497. ISSN 1051-0443

Wroten, Mathew, Yoon, Seungtai, Andrews, Peter, Yamrom, Boris, Ronemus, Michael, Buja, Andreas, Krieger, Abba M, Levy, Dan, Ye, Kenny, Wigler, Michael, Iossifov, Ivan (June 2023) Sharing parental genomes by siblings concordant or discordant for autism. Cell Genomics, 3 (6). p. 100319. ISSN 2666-979X (Public Dataset)

Caballero, Carmela, Irrthum, Alexandre, Goulioti, Theodora, Cameron, David, Norton, Larry, Piccart, Martine (May 2023) International research to address the challenges of metastatic breast cancer: the AURORA Program (BIG 14-01). npj Breast Cancer, 9 (1). p. 42. ISSN 2374-4677

Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Ele, Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) (April 2023) Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials. The Lancet, 401 (10384). pp. 1277-1292. ISSN 0140-6736

Weistuch, Corey, Murgas, Kevin A, Zhu, Jiening, Norton, Larry, Dill, Ken A, Deasy, Joseph O, Tannenbaum, Allen R (April 2023) Cancer heterogeneity is defined by normal cellular trade-offs. bioRxiv. (Submitted)

Rozowsky, Joel, Gao, Jiahao, Borsari, Beatrice, Yang, Yucheng T, Galeev, Timur, Gürsoy, Gamze, Epstein, Charles B, Xiong, Kun, Xu, Jinrui, Li, Tianxiao, Liu, Jason, Yu, Keyang, Berthel, Ana, Chen, Zhanlin, Navarro, Fabio, Sun, Maxwell S, Wright, James, Chang, Justin, Cameron, Christopher JF, Shoresh, Noam, Gaskell, Elizabeth, Drenkow, Jorg, Adrian, Jessika, Aganezov, Sergey, Aguet, François, Balderrama-Gutierrez, Gabriela, Banskota, Samridhi, Corona, Guillermo Barreto, Chee, Sora, Chhetri, Surya B, Cortez Martins, Gabriel Conte, Danyko, Cassidy, Davis, Carrie A, Farid, Daniel, Farrell, Nina P, Gabdank, Idan, Gofin, Yoel, Gorkin, David U, Gu, Mengting, Hecht, Vivian, Hitz, Benjamin C, Issner, Robbyn, Jiang, Yunzhe, Kirsche, Melanie, Kong, Xiangmeng, Lam, Bonita R, Li, Shantao, Li, Bian, Li, Xiqi, Lin, Khine Zin, Luo, Ruibang, Mackiewicz, Mark, Meng, Ran, Moore, Jill E, Mudge, Jonathan, Nelson, Nicholas, Nusbaum, Chad, Popov, Ioann, Pratt, Henry E, Qiu, Yunjiang, Ramakrishnan, Srividya, Raymond, Joe, Salichos, Leonidas, Scavelli, Alexandra, Schreiber, Jacob M, Sedlazeck, Fritz J, See, Lei Hoon, Sherman, Rachel M, Shi, Xu, Shi, Minyi, Sloan, Cricket Alicia, Strattan, J Seth, Tan, Zhen, Tanaka, Forrest Y, Vlasova, Anna, Wang, Jun, Werner, Jonathan, Williams, Brian, Xu, Min, Yan, Chengfei, Yu, Lu, Zaleski, Christopher, Zhang, Jing, Ardlie, Kristin, Cherry, J Michael, Mendenhall, Eric M, Noble, William S, Weng, Zhiping, Levine, Morgan E, Dobin, Alexander, Wold, Barbara, Mortazavi, Ali, Ren, Bing, Gillis, Jesse, Myers, Richard M, Snyder, Michael P, Choudhary, Jyoti, Milosavljevic, Aleksandar, Schatz, Michael C, Bernstein, Bradley E, Guigó, Roderic, Gingeras, Thomas R, Gerstein, Mark (March 2023) The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models. Cell, 186 (7). 1493-1511.e40. ISSN 0092-8674

Lammertse, E, Li, S, Kendall, J, Kim, C, Morris, P, Ranade, N, Levy, D, Wigler, M, Brouzes, E (January 2023) Magnetically Functionalized Hydrogels for High-Throughput Genomic Applications. Advanced Materials Technologies. ISSN 2365-709X

Taylor, C, Dodwell, D, McGale, P, Hills, RK, Berry, R, Bradley, R, Braybrooke, J, Clarke, M, Gray, R, Holt, F, Liu, Z, Pan, H, Peto, R, Straiton, E, Coles, C, Duane, F, Hennequin, C, Jones, G, Kühn, T, Oliveros, S, Overgaard, J, Pritchard, KI, Suh, CO, Beake, G, Boddington, C, Davies, C, Davies, L, Evans, V, Gay, J, Gettins, L, Godwin, J, James, S, Kerr, A, Liu, H, MacKinnon, E, Mannu, G, McHugh, T, Morris, P, Nakahara, M, Read, S, Taylor, H, Ferguson, J, Scheurlen, H, Zurrida, S, Galimberti, V, Ingle, J, Valagussa, P, Veronesi, U, Anderson, S, Tang, G, Fisher, B, Fossa, S, Valborg Reinertsen, K, Host, H, Muss, H, Holli, K, Albain, K, Arriagada, R, Bartlett, J, Bergsten-Nordström, E, Bliss, J, Brain, E, Carey, L, Coleman, R, Cuzick, J, Davidson, N, Del Mastro, L, Di Leo, A, Dignam, J, Dowsett, M, Ejlertsen, B, Francis, P, García-Sáenz, JA, Gelber, R, Gnant, M, Goetz, M, Goodwin, P, Halpin-Murphy, P, Hayes, D, Hill, C, Jagsi, R, Janni, W, Loibl, S, Mamounas, E, Martín, M, McIntosh, S, Mukai, H, Nekljudova, V, Norton, L, Ohashi, Y, Piccart, M, Pierce, L, Raina, V, Rea, D, Regan, M, Robertson, J, Rutgers, E, Salgado, R, Slamon, D, Spanic, T (January 2023) Radiotherapy to regional nodes in early breast cancer: an individual patient data meta-analysis of 14 324 women in 16 trials. The Lancet. ISSN 0140-6736

Ginsberg, Stephen D, Sharma, Sahil, Norton, Larry, Chiosis, Gabriela (January 2023) Targeting stressor-induced dysfunctions in protein-protein interaction networks via epichaperomes. Trends in Pharmacological Sciences, 44 (1). pp. 20-33. ISSN 0165-6147

Abou-Alfa, Ghassan K, Norton, Larry, Global Oncology Medical Diplomacy Working Group (2023) Global Oncology Medical Diplomacy Working Group Inaugural Meeting: Defining Worldwide Barriers to Germline Genomics in Cancer Prevention and Management. Annals of Global Health, 89 (1). p. 16. ISSN 2214-9996

Bignon, Christophe, Gruet, Antoine, Longhi, Sonia (October 2022) Split-GFP Reassembly Assay: Strengths and Caveats from a Multiparametric Analysis. International Journal of Molecular Sciences, 23 (21). p. 13167. ISSN 1422-0067

Wang, Zihua, Moffitt, Andrea B, Andrews, Peter, Wigler, Michael, Levy, Dan (September 2022) Accurate measurement of microsatellite length by disrupting its tandem repeat structure. Nucleic Acids Research. gkac723. ISSN 0305-1048

Sacchini, Virgilio, Norton, Larry (September 2022) Escalating de-escalation in breast cancer treatment. Breast Cancer Research and Treatment, 195 (2). pp. 85-90. ISSN 0167-6806

Baslan, Timour, Morris, John P, Zhao, Zhen, Reyes, Jose, Ho, Yu-Jui, Tsanov, Kaloyan M, Bermeo, Jonathan, Tian, Sha, Zhang, Sean, Askan, Gokce, Yavas, Aslihan, Lecomte, Nicolas, Erakky, Amanda, Varghese, Anna M, Zhang, Amy, Kendall, Jude, Ghiban, Elena, Chorbadjiev, Lubomir, Wu, Jie, Dimitrova, Nevenka, Chadalavada, Kalyani, Nanjangud, Gouri J, Bandlamudi, Chaitanya, Gong, Yixiao, Donoghue, Mark TA, Socci, Nicholas D, Krasnitz, Alex, Notta, Faiyaz, Leach, Steve D, Iacobuzio-Donahue, Christine A, Lowe, Scott W (August 2022) Ordered and deterministic cancer genome evolution after p53 loss. Nature. ISSN 0028-0836

Grabenstetter, Anne, Brogi, Edi, Zhang, Hong, Razavi, Pedram, Reis-Filho, Jorge S, VanZee, Kimberly J, Norton, Larry, Wen, Hannah Y (August 2022) Solid-basaloid variant of adenoid cystic carcinoma of the breast with near complete response to neoadjuvant chemotherapy. npj Breast Cancer, 8 (1). p. 93. ISSN 2374-4677

Li, Siran, Park, Sarah, Ye, Catherine, Danyko, Cassidy, Wroten, Matthew, Andrews, Peter, Wigler, Michael, Levy, Dan (July 2022) Targeted de novo phasing and long-range assembly by template mutagenesis. Nucleic Acids Research. ISSN 0305-1048

ENCODE Project Consortium, Moore, Jill E, Purcaro, Michael J, Pratt, Henry E, Epstein, Charles B, Shoresh, Noam, Adrian, Jessika, Kawli, Trupti, Davis, Carrie A, Dobin, Alexander, Kaul, Rajinder, Halow, Jessica, Van Nostrand, Eric L, Freese, Peter, Gorkin, David U, Shen, Yin, He, Yupeng, Mackiewicz, Mark, Pauli-Behn, Florencia, Williams, Brian A, Mortazavi, Ali, Keller, Cheryl A, Zhang, Xiao-Ou, Elhajjajy, Shaimae I, Huey, Jack, Dickel, Diane E, Snetkova, Valentina, Wei, Xintao, Wang, Xiaofeng, Rivera-Mulia, Juan Carlos, Rozowsky, Joel, Zhang, Jing, Chhetri, Surya B, Zhang, Jialing, Victorsen, Alec, White, Kevin P, Visel, Axel, Yeo, Gene W, Burge, Christopher B, Lécuyer, Eric, Gilbert, David M, Dekker, Job, Rinn, John, Mendenhall, Eric M, Ecker, Joseph R, Kellis, Manolis, Klein, Robert J, Noble, William S, Kundaje, Anshul, Guigó, Roderic, Farnham, Peggy J, Cherry, J Michael, Myers, Richard M, Ren, Bing, Graveley, Brenton R, Gerstein, Mark B, Pennacchio, Len A, Snyder, Michael P, Bernstein, Bradley E, Wold, Barbara, Hardison, Ross C, Gingeras, Thomas R, Stamatoyannopoulos, John A, Weng, Zhiping (May 2022) Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature, 605 (7909). E3. ISSN 0028-0836

ENCODE Project Consortium, Snyder, Michael P, Gingeras, Thomas R, Moore, Jill E, Weng, Zhiping, Gerstein, Mark B, Ren, Bing, Hardison, Ross C, Stamatoyannopoulos, John A, Graveley, Brenton R, Feingold, Elise A, Pazin, Michael J, Pagan, Michael, Gilchrist, Daniel A, Hitz, Benjamin C, Cherry, J Michael, Bernstein, Bradley E, Mendenhall, Eric M, Zerbino, Daniel R, Frankish, Adam, Flicek, Paul, Myers, Richard M (May 2022) Author Correction: Perspectives on ENCODE. Nature, 605 (7909). E4. ISSN 0028-0836

Page, David B, Beal, Kathryn, Linch, Stefanie N, Spinelli, Kateri J, Rodine, Micaela, Halpenny, Darragh, Modi, Shanu, Patil, Sujata, Young, Robert J, Kaley, Thomas, Merghoub, Taha, Redmond, David, Wong, Phillip, Barker, Christopher A, Diab, Adi, Norton, Larry, McArthur, Heather L (April 2022) Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/- trastuzumab in patients with breast cancer brain metastases. npj Breast Cancer, 8 (1). p. 50. ISSN 2374-4677

Ferraro, Emanuela, Singh, Jasmeet, Patil, Sujata, Razavi, Pedram, Modi, Shanu, Chandarlapaty, Sarat, Barrio, Andrea V, Malani, Rachna, Mellinghoff, Ingo K, Boire, Adrienne, Wen, Hannah Y, Brogi, Edi, Seidman, Andrew D, Norton, Larry, Robson, Mark E, Dang, Chau T (March 2022) Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab. npj Breast Cancer, 8 (1). p. 37. ISSN 2374-4677

Ren, Zuen, Liang, Huizhi, Galbo, Phillip M, Dharmaratne, Malindrie, Kulkarni, Ameya S, Fard, Atefeh Taherian, Aoun, Marie Louise, Martinez-Lopez, Nuria, Suyama, Kimita, Benard, Outhiriaradjou, Zheng, Wei, Liu, Yang, Albanese, Joseph, Zheng, Deyou, Mar, Jessica C, Singh, Rajat, Prystowsky, Michael B, Norton, Larry, Hazan, Rachel B (February 2022) Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer. Proceedings of the National Academy of Sciences of USA, 119 (8). e2107266119-e2107266119. ISSN 0027-8424

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Plenker, Dennis, Tuveson, David A, Rishi, Arvind, Wilkinson, John E, McCombie, W Richard, Kostroff, Karen, Spector, David L (February 2022) Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics. Cancer Research. ISSN 0008-5472

Fraenkel, Merav, Novack, Victor, Mizrakli, Yuval, Koretz, Michael, Siris, Ethel, Norton, Larry, Shafat, Tali, Geffen, David B (February 2022) Bone mineral density in women newly diagnosed with breast cancer: a prospective cohort study. npj Breast Cancer, 8 (1). p. 21. ISSN 2374-4677

Early Breast Cancer Trialists' Collaborative Group (EBCTCG) (February 2022) Aromatase inhibitors versus tamoxifen in premenopausal women with oestrogen receptor-positive early-stage breast cancer treated with ovarian suppression: a patient-level meta-analysis of 7030 women from four randomised trials. The Lancet Oncology. ISSN 1470-2045

van den Bruele, Astrid Botty, Sevilimedu, Varadan, Jochelson, Maxine, Formenti, Silvia, Norton, Larry, Sacchini, Virgilio (January 2022) Mobile mammography in New York City: analysis of 32,350 women utilizing a screening mammogram program. npj Breast Cancer, 8 (1). p. 14. ISSN 2374-4677

Hanasoge Somasundara, Amritha Varshini, Moss, Matthew A, Feigman, Mary J, Chen, Chen, Cyrill, Samantha L, Ciccone, Michael F, Trousdell, Marygrace C, Vollbrecht, Macy, Li, Siran, Kendall, Jude, Beyaz, Semir, Wilkinson, John E, Dos Santos, Camila O (December 2021) Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis. Cell Reports, 37 (10). p. 110099. ISSN 2211-1247

Elkin, Rena, Oh, Jung Hun, Liu, Ying L, Selenica, Pier, Weigelt, Britta, Reis-Filho, Jorge S, Zamarin, Dmitriy, Deasy, Joseph O, Norton, Larry, Levine, Arnold J, Tannenbaum, Allen R (November 2021) Geometric network analysis provides prognostic information in patients with high grade serous carcinoma of the ovary treated with immune checkpoint inhibitors. npj Genomic Medicine, 6 (1). p. 99. ISSN 2056-7944

Bolton, Kelly L, Koh, Youngil, Foote, Michael B, Im, Hogune, Jee, Justin, Sun, Choong Hyun, Safonov, Anton, Ptashkin, Ryan, Moon, Joon Ho, Lee, Ji Yeon, Jung, Jongtak, Kang, Chang Kyung, Song, Kyoung-Ho, Choe, Pyoeng Gyun, Park, Wan Beom, Kim, Hong Bin, Oh, Myoung-Don, Song, Han, Kim, Sugyeong, Patel, Minal, Derkach, Andriy, Gedvilaite, Erika, Tkachuk, Kaitlyn A, Wiley, Brian J, Chan, Ireaneus C, Braunstein, Lior Z, Gao, Teng, Papaemmanuil, Elli, Esther Babady, N, Pessin, Melissa S, Kamboj, Mini, Diaz, Luis A, Ladanyi, Marc, Rauh, Michael J, Natarajan, Pradeep, Machiela, Mitchell J, Awadalla, Philip, Joseph, Vijai, Offit, Kenneth, Norton, Larry, Berger, Michael F, Levine, Ross L, Kim, Eu Suk, Kim, Nam Joong, Zehir, Ahmet (October 2021) Clonal hematopoiesis is associated with risk of severe Covid-19. Nature Communications, 12 (1). p. 5975. ISSN 2041-1723

Schwartz, Christopher J, Brogi, Edi, Marra, Antonio, Da Cruz Paula, Arnaud F, Nanjangud, Gouri J, da Silva, Edaise M, Patil, Sujata, Shah, Shreena, Ventura, Katia, Razavi, Pedram, Norton, Larry, D'alfonso, Timothy, Weigelt, Britta, Pareja, Fresia, Reis-Filho, Jorge S, Wen, Hannah Y (October 2021) The clinical behavior and genomic features of the so-called adenoid cystic carcinomas of the solid variant with basaloid features. Modern Pathology. ISSN 0893-3952

Yoon, Seungtai, Munoz, Adriana, Yamrom, Boris, Lee, Yoon-Ha, Andrews, Peter, Marks, Steven, Wang, Zihua, Reeves, Catherine, Winterkorn, Lara, Krieger, Abba M, Buja, Andreas, Pradhan, Kith, Ronemus, Michael, Baldwin, Kristin K, Levy, Dan, Wigler, Michael, Iossifov, Ivan (September 2021) Rates of contributory de novo mutation in high and low-risk autism families. Communications Biology, 4 (1). p. 1026. ISSN 2399-3642

Ward, Zachary J, Atun, Rifat, Hricak, Hedvig, Asante, Kwanele, McGinty, Geraldine, Sutton, Elizabeth J, Norton, Larry, Scott, Andrew M, Shulman, Lawrence N (August 2021) The impact of scaling up access to treatment and imaging modalities on global disparities in breast cancer survival: a simulation-based analysis. The Lancet Oncology. ISSN 1470-2045

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter A, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Rishi, Arvind, Wilkinson, John Erby, McCombie, William Richard, Kostroff, Karen, Spector, David L (August 2021) Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics. BioRxiv.

Lukow, Devon A, Sausville, Erin L, Suri, Pavit, Chunduri, Narendra Kumar, Wieland, Angela, Leu, Justin, Smith, Joan C, Girish, Vishruth, Kumar, Ankith A, Kendall, Jude, Wang, Zihua, Storchova, Zuzana, Sheltzer, Jason M (August 2021) Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies. Developmental Cell. ISSN 1534-5807

Bradley, R, Braybrooke, J, Gray, R, Hills, R, Liu, Z, Peto, R, Davies, L, Dodwell, D, McGale, P, Pan, H, Taylor, C, Anderson, S, Gelber, R, Gianni, L, Jacot, W, Joensuu, H, Moreno-Aspitia, A, Piccart, M, Press, M, Romond, E, Slamon, D, Suman, V, Berry, R, Boddington, C, Clarke, M, Davies, C, Duane, F, Evans, V, Gay, J, Gettins, L, Godwin, J, James, S, Liu, H, MacKinnon, E, Mannu, G, McHugh, T, Morris, P, Read, S, Straiton, E, Wang, Y, Crown, J, de Azambuja, E, Delaloge, S, Fung, H, Geyer, C, Spielmann, M, Valagussa, P, Albain, K, Arriagada, R, Bartlett, J, Bergsten-Nordström, E, Bliss, J, Brain, E, Carey, L, Coleman, R, Cuzick, J, Davidson, N, Del Mastro, L, Di Leo, A, Dignam, J, Dowsett, M, Ejlertsen, B, Francis, P, Gnant, M, Goetz, M, Goodwin, P, Halpin-Murphy, P, Hayes, D, Hill, C, Jagsi, R, Janni, W, Loibl, S, Mamounas, EP, Martín, M, Mukai, H, Nekljudova, V, Norton, L, Ohashi, Y, Pierce, L, Poortmans, P, Raina, V, Rea, D, Regan, M, Robertson, J, Rutgers, E, Spanic, T, Sparano, J, Steger, G, Tang, G, Toi, M, Tutt, A, Viale, G, Wang, X, Whelan, T, Wilcken, N, Wolmark, N, Cameron, D, Bergh, J, Pritchard, KI, Swain, SM (August 2021) Trastuzumab for early-stage, HER2-positive breast cancer: a meta-analysis of 13 864 women in seven randomised trials. The Lancet Oncology, 22 (8). pp. 1139-1150. ISSN 1470-2045

Wong, Willard, Brogi, Edi, Reis-Filho, Jorge S, Plitas, George, Robson, Mark, Norton, Larry, Morrow, Monica, Wen, Hannah Y (July 2021) Poor response to neoadjuvant chemotherapy in metaplastic breast carcinoma. npj Breast Cancer, 7 (1). p. 96. ISSN 2374-4677

Kumar, Rakesh, Hortobagy, Gabriel N, Albanell, Joan, Arribas, Joaquín, Norton, Larry (June 2021) In Memoriam: José Baselga's Journey in Cancer Medicine. Clinical Cancer Research, 27 (12). pp. 3499-3502. ISSN 1078-0432

Wojnarowicz, Paulina M, Escolano, Marta Garcia, Huang, Yun-Han, Desai, Bina, Chin, Yvette, Shah, Riddhi, Xu, Sijia, Yadav, Saurabh, Yaklichkin, Sergey, Ouerfelli, Ouathek, Soni, Rajesh Kumar, Philip, John, Montrose, David C, Healey, John H, Rajasekhar, Vinagolu K, Garland, William A, Ratiu, Jeremy, Zhuang, Yuan, Norton, Larry, Rosen, Neal, Hendrickson, Ronald C, Zhou, Xi Kathy, Iavarone, Antonio, Massague, Joan, Dannenberg, Andrew J, Lasorella, Anna, Benezra, Robert (May 2021) Anti-tumor effects of an ID antagonist with no observed acquired resistance. npj Breast Cancer, 7 (1). p. 58. ISSN 2374-4677

da Silva, Edaise M, Selenica, Pier, Vahdatinia, Mahsa, Pareja, Fresia, Da Cruz Paula, Arnaud, Ferrando, Lorenzo, Gazzo, Andrea M, Dopeso, Higinio, Ross, Dara S, Bakhteri, Ariya, Riaz, Nadeem, Chandarlapaty, Sarat, Razavi, Pedram, Norton, Larry, Wen, Hannah Y, Brogi, Edi, Weigelt, Britta, Zhang, Hong, Reis-Filho, Jorge S (April 2021) TERT promoter hotspot mutations and gene amplification in metaplastic breast cancer. npj Breast Cancer, 7 (1). p. 43. ISSN 2374-4677

Moukarzel, Lea A, Ferrando, Lorenzo, Da Cruz Paula, Arnaud, Brown, David N, Geyer, Felipe C, Pareja, Fresia, Piscuoglio, Salvatore, Papanastasiou, Anastasios D, Fusco, Nicola, Marchiò, Caterina, Abu-Rustum, Nadeem R, Murali, Rajmohan, Brogi, Edi, Wen, Hannah Y, Norton, Larry, Soslow, Robert A, Vincent-Salomon, Anne, Reis-Filho, Jorge S, Weigelt, Britta (April 2021) The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas. Molecular Oncology, 15 (4). pp. 1024-1039. ISSN 1574-7891

Belkhatir, Zehor, Pavon, Michele, Mathews, James C, Pouryahya, Maryam, Deasy, Joseph O, Norton, Larry, Tannenbaum, Allen R (March 2021) Stochastic Norton-Simon-Massague Tumor Growth Modeling: Controlled and Mixed-Effect Uncontrolled Analysis. IEEE Transactions on Control Systems Technology, 29 (2). pp. 704-717. ISSN 1063-6536

Seidman, Andrew D, de Stanchina, Elisa, Norton, Larry, Morikawa, Aki (January 2021) Comparative Effectiveness Research Needs to Consider Optimal Dosing and Scheduling. Journal of Clinical Oncology, 39 (3). pp. 253-254. ISSN 0732-183X

Sutton, Elizabeth J, Braunstein, Lior Z, El-Tamer, Mahmoud B, Brogi, Edi, Hughes, Mary, Bryce, Yolanda, Gluskin, Jill S, Powell, Simon, Woosley, Alyssa, Tadros, Audree, Sevilimedu, Varadan, Martinez, Danny F, Toni, Larowin, Smelianskaia, Olga, Nyman, C Gregory, Razavi, Pedram, Norton, Larry, Fung, Maggie M, Sedorovich, James D, Sacchini, Virgilio, Morris, Elizabeth A (January 2021) Accuracy of Magnetic Resonance Imaging-Guided Biopsy to Verify Breast Cancer Pathologic Complete Response After Neoadjuvant Chemotherapy: A Nonrandomized Controlled Trial. Jama Network Open, 4 (1). e2034045. ISSN 2574-3805

Piccart, Martine J, Hilbers, Florentine S, Bliss, Judith M, Caballero, Carmela, Frank, Elizabeth S, Renault, Patrick, Naït Kaoudjt, Rachida, Schumacher, Eva, Spears, Patricia A, Regan, Meredith M, Gelber, Richard D, Davidson, Nancy E, Norton, Larry, Winer, Eric P, BIG-NABCG Collaboration (December 2020) Road Map to Safe and Well-Designed De-escalation Trials of Systemic Adjuvant Therapy for Solid Tumors. Journal of Clinical Oncology, 38 (34). pp. 4120-4129. ISSN 0732-183X

Cardoso, F, Paluch-Shimon, S, Senkus, E, Curigliano, G, Aapro, MS, André, F, Barrios, CH, Bergh, J, Bhattacharyya, GS, Biganzoli, L, Boyle, F, Cardoso, M-J, Carey, LA, Cortés, J, El Saghir, NS, Elzayat, M, Eniu, A, Fallowfield, L, Francis, PA, Gelmon, K, Gligorov, J, Haidinger, R, Harbeck, N, Hu, X, Kaufman, B, Kaur, R, Kiely, BE, Kim, S-B, Lin, NU, Mertz, SA, Neciosup, S, Offersen, BV, Ohno, S, Pagani, O, Prat, A, Penault-Llorca, F, Rugo, HS, Sledge, GW, Thomssen, C, Vorobiof, DA, Wiseman, T, Xu, B, Norton, L, Costa, A, Winer, EP (December 2020) 5th ESO-ESMO international consensus guidelines for advanced breast cancer (ABC 5). Annals of Oncology, 31 (12). pp. 1623-1649. ISSN 0923-7534

Jobanputra, Vaidehi, Andrews, Peter, Felice, Vanessa, Abhyankar, Avinash, Kozon, Lukasz, Robinson, Dino, London, Ferrah, Hakker, Inessa, Wrzeszczynski, Kazimierz, Ronemus, Michael (December 2020) Detection of Copy Number Variants by Short Multiply Aggregated Sequence Homologies. The Journal of Molecular Diagnostics, 22 (12). pp. 1476-1481. ISSN 1525-1578

Abel, Haley J, Larson, David E, Regier, Allison A, Chiang, Colby, Das, Indraniel, Kanchi, Krishna L, Layer, Ryan M, Neale, Benjamin M, Salerno, William J, Reeves, Catherine, Buyske, Steven, NHGRI Centers for Common Disease Genomics, Matise, Tara C, Muzny, Donna M, Zody, Michael C, Lander, Eric S, Dutcher, Susan K, Stitziel, Nathan O, Hall, Ira M (July 2020) Mapping and characterization of structural variation in 17,795 human genomes. Nature, 583 (7814). pp. 83-89. ISSN 0028-0836

Chorbadjiev, L., Kendall, J., Alexander, J., Zhygulin, V., Song, J., Wigler, M., Krasnitz, A. (May 2020) Integrated Computational Pipeline for Single-Cell Genomic Profiling. JCO Clinical Cancer Informatics, 4. pp. 464-471.

Baslan, T., Kendall, J., Volyanskyy, K., McNamara, K., Cox, H., D'Italia, S., Ambrosio, F., Riggs, M., Rodgers, L., Leotta, A., Song, J., Mao, Y., Wu, J., Shah, R., Gularte-Merida, R., Chadalavada, K., Nanjangud, G., Varadan, V., Gordon, A., Curtis, C., Krasnitz, A., Dimitrova, N., Harris, L., Wigler, M., Hicks, J. (May 2020) Novel Insights Into Breast Cancer Copy Number Genetic Heterogeneity Revealed by Single-Cell Genome Sequencing. Elife, 9. e51480. ISSN 2050-084X

Vasudevan, A., Baruah, P.S., Smith, J.C., Wang, Z., Sayles, N. M., Andrews, P., Kendall, J., Leu, J., Chunduri, N.K., Levy, D., Wigler, M., Storchova, Z., Sheltzer, J. M. (February 2020) Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer. Developmental Cell, 52 (4). pp. 413-428. ISSN 1534-5807

Moffitt, A. B., Spector, M. S., Andrews, P., Kendall, J., Alexander, J., Stepansky, A., Ma, B., Kolitz, J., Chiorazzi, N., Allen, S.L., Krasnitz, A., Wigler, M., Levy, D., Wang, Z. (February 2020) Multiplex Accurate Sensitive Quantitation (MASQ) With Application to Minimal Residual Disease in Acute Myeloid Leukemia. Nucleic Acids Research, 48 (7). e40. ISSN 0305-1048 (Public Dataset)

Li, S., Kendall, J., Park, S., Wang, Z., Alexander, J., Moffitt, A., Ranade, N., Danyko, C., Gegenhuber, B., Fischer, S., Robinson, B. D., Lepor, H., Tollkuhn, J., Gillis, J., Brouzes, E., Krasnitz, A., Levy, D., Wigler, M. (November 2019) Copolymerization of single-cell nucleic acids into balls of acrylamide gel. Genome Res, 30 (1). pp. 49-61. ISSN 1088-9051 (Public Dataset)

Liang, D., McHugh, K. M., Brophy, P. D., Shaikh, N., Manak, J. R., Andrews, P., Hakker, I., Wang, Z., Schwaderer, A. L., Hains, D. S. (August 2019) DNA copy number variations in children with vesicoureteral reflux and urinary tract infections. PLoS One, 14 (8). e0220617. ISSN 1932-6203

Buja, A., Volfovsky, N., Krieger, A. M., Lord, C., Lash, A. E., Wigler, M., Iossifov, I. (February 2018) Damaging de novo mutations diminish motor skills in children on the autism spectrum. Proc Natl Acad Sci U S A, 115 (8). E1859-E1866. ISSN 0027-8424

Rodriguez-Lee, M., Kolatkar, A., McCormick, M., Dago, A. D., Kendall, J., Carlsson, N. A., Bethel, K., Greenspan, E. J., Hwang, S. E., Waitman, K. R., Nieva, J. J., Hicks, J., Kuhn, P. (February 2018) Effect of Blood Collection Tube Type and Time to Processing on the Enumeration and High-Content Characterization of Circulating Tumor Cells Using the High-Definition Single-Cell Assay. Arch Pathol Lab Med, 142 (2). pp. 198-207. ISSN 0003-9985

Kumar, V., Rosenbaum, J., Wang, Z., Forcier, T., Ronemus, M., Wigler, M., Levy, D. (January 2018) Partial bisulfite conversion for unique template sequencing. Nucleic Acids Res, 46 (2). e10. ISSN 0305-1048

Alexander, J., Kendall, J., McIndoo, J., Rodgers, L., Aboukhalil, R., Levy, D., Stepansky, A., Sun, G., Chobadjiev, L., Riggs, M., Cox, H., Hakker, I., Nowak, D. G., Laze, J., Llukani, E., Srivastava, A., Gruschow, S., Yadav, S. S., Robinson, B. D., Atwal, G., Trotman, L. C., Lepor, H., Hicks, J. B., Wigler, M., Krasnitz, A. (January 2018) Utility of single cell genomics in diagnostic evaluation of prostate cancer. Cancer Res, 78 (2). pp. 348-358. ISSN 0008-5472

Ye, K., Iossifov, I., Levy, D., Yamrom, B., Buja, A., Krieger, A. M., Wigler, M. (July 2017) Measuring shared variants in cohorts of discordant siblings with applications to autism. Proc Natl Acad Sci U S A, 114 (27). pp. 7073-7076. ISSN 0027-8424

Krasnitz, Alexander, Kendall, Jude, Alexander, Joan, Levy, Dan, Wigler, Michael (July 2017) Early Detection of Cancer in Blood Using Single-Cell Analysis: A Proposal. Trends in Molecular Medicine, 23 (7). pp. 594-603. ISSN 1471-4914

Kumar, Vijay, Rosenbaum, Julie, Wang, Zihua, Forcier, Talitha, Ronemus, Michael, Wigler, Michael, Levy, Dan (June 2017) Mutational sequencing for accurate count and long-range assembly. bioRxiv.

Munoz, Adriana, Yamrom, Boris, Lee, Yoon-ha, Andrews, Peter, Marks, Steven, Lin, Kuan-Ting, Wang, Zihua, Krainer, Adrian R., Darnell, Robert B., Wigler, Michael, Iossifov, Ivan (May 2017) De novo indels within introns contribute to ASD incidence. bioRxiv. p. 137471. (Unpublished)

Martelotto, L. G., Baslan, T., Kendall, J., Geyer, F. C., Burke, K. A., Spraggon, L., Piscuoglio, S., Chadalavada, K., Nanjangud, G., Ng, C. K., Moody, P., D'Italia, S., Rodgers, L., Cox, H., da Cruz Paula, A., Stepansky, A., Schizas, M., Wen, H. Y., King, T. A., Norton, L., Weigelt, B., Hicks, J. B., Reis-Filho, J. S. (March 2017) Whole-genome single-cell copy number profiling from formalin-fixed paraffin-embedded samples. Nat Med, 23 (3). pp. 376-385. ISSN 1546-170X (Electronic)1078-8956 (Linking)

Pal, D., Pertot, A., Shirole, N. H., Yao, Z., Anaparthy, N., Garvin, T., Cox, H., Chang, K., Rollins, F., Kendall, J., Edwards, L., Singh, V. A., Stone, G. C., Schatz, M. C., Hicks, J., Hannon, G., Sordella, R. (January 2017) TGF-beta reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells. Elife, 6. ISSN 2050-084X (Electronic)2050-084X (Linking)

Fang, H., Bergmann, E. A., Arora, K., Vacic, V., Zody, M. C., Iossifov, I., O'Rawe, J. A., Wu, Y., Jimenez Barron, L. T., Rosenbaum, J., Ronemus, M., Lee, Y. H., Wang, Z., Dikoglu, E., Jobanputra, V., Lyon, G. J., Wigler, M., Schatz, M. C., Narzisi, G. (December 2016) Indel variant analysis of short-read sequencing data with Scalpel. Nat Protoc, 11 (12). pp. 2529-2548. ISSN 1750-2799 (Electronic)1750-2799 (Linking)

Andrews, Peter A., Iossifov, Ivan, Kendall, Jude, Marks, Steven, Muthuswamy, Lakshmi, Wang, Zihua, Levy, Dan, Wigler, Michael (September 2016) MUMdex: MUM-based structural variation detection. bioRxiv. 078261.

Wang, Z., Andrews, P., Kendall, J., Ma, B., Hakker, I., Rodgers, L., Ronemus, M., Wigler, M., Levy, D. (June 2016) SMASH, a fragmentation and sequencing method for genomic copy number analysis. Genome Res, 26 (6). pp. 844-51. ISSN 1549-5469 (Electronic)1088-9051 (Linking) (Public Dataset)

Baslan, T., Kendall, J., Rodgers, L., Cox, H., Riggs, M., Stepansky, A., Troge, J., Ravi, K., Esposito, D., Lakshmi, B., Wigler, M., Navin, N., Hicks, J. (March 2016) Corrigendum: Genome-wide copy number analysis of single cells. Nat Protoc, 11 (3). p. 616. ISSN 1750-2799

Martelotto, L. G., Baslan, T., Kendall, J., Rodgers, L., Cox, H., King, T. A., Weigelt, B., Hicks, J., Reis, J. S. (February 2016) Single cell sequencing analysis of formalin-fixed paraffin-embedded ductal carcinomas in situ and invasive breast cancers reveals clonal selection in the progression from in situ to invasive disease. Cancer Research, 76 (Supple). Abstract P2-05. ISSN 0008-5472

Homsy, J., Zaidi, S., Shen, Y., Ware, J. S., Samocha, K. E., Karczewski, K. J., DePalma, S. R., McKean, D., Wakimoto, H., Gorham, J., Jin, S. C., Deanfield, J., Giardini, A., Porter G.A, Jr., Kim, R., Bilguvar, K., López-Giráldez, F., Tikhonova, I., Mane, S., Romano-Adesman, A., Qi, H., Vardarajan, B., Ma, L., Daly, M., Roberts, A. E., Russell, M. W., Mital, S., Newburger, J. W., Gaynor, J. W., Breitbart, R. E., Iossifov, I., Ronemus, M., Sanders, S. J., Kaltman, J. R., Seidman, J. G., Brueckner, M., Gelb, B. D., Goldmuntz, E., Lifton, R. P., Seidman, C. E., Chung, W. K. (December 2015) De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies. Science, 350 (6265). pp. 1262-1266. ISSN 00368075

Kusenda, M., Vacic, V., Malhotra, D., Rodgers, L., Pavon, K., Meth, J., Kumar, R. A., Christian, S. L., Peeters, H., Cho, S. S., Addington, A., Rapoport, J. L., Sebat, J. (December 2015) The Influence of Microdeletions and Microduplications of 16p11.2 on Global Transcription Profiles. J Child Neurol, 30 (14). pp. 1947-1953. ISSN 1708-8283 (Electronic)0883-0738 (Linking)

Garvin, T., Aboukhalil, R., Kendall, J., Baslan, T., Atwal, G. S., Hicks, J., Wigler, M., Schatz, M. C. (November 2015) Interactive analysis and assessment of single-cell copy-number variations. Nat Methods, 12. pp. 1058-1060. ISSN 1548-7105 (Electronic)1548-7091 (Linking) (Public Dataset)

Iossifov, I., Levy, D., Allen, J., Ye, K., Ronemus, M., Lee, Y. H., Yamrom, B., Wigler, M. (September 2015) Low load for disruptive mutations in autism genes and their biased transmission. Proc Natl Acad Sci U S A. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Velasco, C. R., Stepansky, A., Dago, A., Carlson, A., Kolatkar, A., Kendall, J., Hicks, J., Kuhn, P. (August 2015) Single-cell molecular profiling of fluid biopsies of epithelial ovarian cancer. Clinical Cancer Research, 21. ISSN 1078-0432

Baslan, T., Kendall, J., Ward, B., Cox, H., Leotta, A., Rodgers, L., Riggs, M., D'Italia, S., Sun, G., Yong, M., Miskimen, K., Gilmore, H., Saborowski, M., Dimitrova, N., Krasnitz, A., Harris, L., Wigler, M., Hicks, J. (May 2015) Optimizing sparse sequencing of single cells for highly multiplex copy number profiling. Genome Research, 25 (5). pp. 714-724. ISSN 1088-9051

Rye, I. H., Lundin, P., Maner, S., Fjelldal, R., Naume, B., Wigler, M., Hicks, J., Borresen-Dale, A. L., Zetterberg, A., Russnes, H. G. (April 2015) Quantitative multigene FISH on breast carcinomas identifies der(1;16)(q10;p10) as an early event in luminal A tumors. Genes, Chromosomes & Cancer, 54 (4). pp. 235-48. ISSN 1045-2257

Mukhopadhyay, Swagatam, Wigler, Michael, Levy, Dan (March 2015) Simple genetic models for autism spectrum disorder. bioRxiv. 017301.

Jayaprakash, A. D., Benson, E. K., Gone, S., Liang, R., Shim, J., Lambertini, L., Toloue, M. M., Wigler, M., Aaronson, S. A., Sachidanandam, R. (February 2015) Stable heteroplasmy at the single-cell level is facilitated by intercellular exchange of mtDNA. Nucleic Acids Research, 43 (4). pp. 2177-2187. ISSN 0305-1048

Ruiz, C., Li, J., Luttgen, M. S., Kolatkar, A., Kendall, J. T., Flores, E., Topp, Z., Samlowski, W. E., McClay, E., Bethel, K., Ferrone, S., Hicks, J., Kuhn, P. (February 2015) Limited genomic heterogeneity of circulating melanoma cells in advanced stage patients. Physical biology, 12 (1). 016008. ISSN 1478-3967

Li, Siran, Stone, Howard A, Murphy, Coleen T (January 2015) A microfluidic device and automatic counting system for the study of C. elegans reproductive aging. Lab on a Chip: miniaturisation for chemistry, physics, biology, materials science and bioengineering, 15 (2). pp. 524-531. ISSN 1473-0197

Garvin, Tyler, Aboukhalil, Robert, Kendall, Jude, Baslan, Timour, Atwal, Gurinder S, Hicks, James, Wigler, Michael, Schatz, Michael (2015) Interactive analysis and quality assessment of single-cell copy-number variations. Nature Methods, 12. pp. 1058-1060. ISSN 15487091 (ISSN)

Nagaraj, V. H., Mukhopadhyay, S., Dayarian, A., Sengupta, A. M. (December 2014) Breaking an Epigenetic Chromatin Switch: Curious Features of Hysteresis in Saccharomyces cerevisiae Telomeric Silencing. PLoS One, 9 (12). e113516. ISSN 1932-6203

Iossifov, I., O'Roak, B. J., Sanders, S. J., Ronemus, M., Krumm, N., Levy, D., Stessman, H. A., Witherspoon, K. T., Vives, L., Patterson, K. E., Smith, J. D., Paeper, B., Nickerson, D. A., Dea, J., Dong, S., Gonzalez, L. E., Mandell, J. D., Mane, S. M., Murtha, M. T., Sullivan, C. A., Walker, M. F., Waqar, Z., Wei, L., Willsey, A. J., Yamrom, B., Lee, Y. H., Grabowska, E., Dalkic, E., Wang, Z., Marks, S., Andrews, P., Leotta, A., Kendall, J., Hakker, I., Rosenbaum, J., Ma, B., Rodgers, L., Troge, J., Narzisi, G., Yoon, S., Schatz, M. C., Ye, K., McCombie, W. R., Shendure, J., Eichler, E. E., State, M. W., Wigler, M. (November 2014) The contribution of de novo coding mutations to autism spectrum disorder. Nature, 515 (7526). pp. 216-221. ISSN 0028-0836

Glessner, J. T., Bick, A. G., Ito, K., Homsy, J. G., Rodriguez-Murillo, L., Fromer, M., Mazaika, E., Vardarajan, B., Italia, M., Leipzig, J., DePalma, S. R., Golhar, R., Sanders, S. J., Yamrom, B., Ronemus, M., Iossifov, I., Willsey, A. J., State, M. W., Kaltman, J. R., White, P. S., Shen, Y., Warburton, D., Brueckner, M., Seidman, C., Goldmuntz, E., Gelb, B. D., Lifton, R., Seidman, J., Hakonarson, H., Chung, W. K. (October 2014) Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence data. Circulation Research, 115 (10). pp. 884-96. ISSN 0009-7330

Levy, D., Wigler, M. (October 2014) Facilitated sequence counting and assembly by template mutagenesis. Proceedings of the National Academy of Sciences of the United States of America, 111 (43). E4632-E4637. ISSN 0027-8424

Narzisi, G., O'Rawe, Jason, Iossifov, I., Fang, Han, Lee, Y. H., Wang, Zihua, Wu, Yiyang, Lyon, Gholson J., Wigler, M. H., Schatz, M. C. (August 2014) Accurate de novo and transmitted indel detection in exome-capture data using microassembly. Nature Methods, 11 (10). pp. 1033-1036.

Dago, A. E., Stepansky, A., Carlsson, A., Luttgen, M., Kendall, J., Baslan, T., Kolatkar, A., Wigler, M., Bethel, K., Gross, M. E., Hicks, J., Kuhn, P. (August 2014) Rapid phenotypic and genomic change in response to therapeutic pressure in prostate cancer inferred by high content analysis of single circulating tumor cells. PLoS One, 9 (8). e101777. ISSN 1932-6203

Kendall, J., Krasnitz, A. (July 2014) Computational methods for DNA copy-number analysis of tumors. Methods in Molecular Biology, 1176. pp. 243-59. ISSN 1940-6029 (Electronic)1064-3745 (Linking)

Warburton, D., Ronemus, M., Kline, J., Jobanputra, V., Williams, I., Anyane-Yeboa, K., Chung, W., Yu, L., Wong, N., Awad, D., Yu, C. Y., Leotta, A., Kendall, J., Yamrom, B., Lee, Y. H., Wigler, M., Levy, D. (January 2014) The contribution of de novo and rare inherited copy number changes to congenital heart disease in an unselected sample of children with conotruncal defects or hypoplastic left heart disease. Human Genetics, 133 (1). pp. 11-27. ISSN 1432-1203 (Electronic)0340-6717 (Linking)

Fang, Han, Wu, Yiyang, Narzisi, G., O'Rawe, Jason, Jimenez Barron, Laura, Rosenbaum, J., Ronemus, M., Iossifov, I., Schatz, M. C., Lyon, Gholson J. (2014) Reducing INDEL calling errors in whole genome and exome sequencing data. Genome Med, 6 (10). p. 89.

Ronemus, M., Iossifov, I., Levy, D., Wigler, M. (2014) The role of de novo mutations in the genetics of autism spectrum disorders. Nature Reviews Genetics, 15 (2). pp. 133-141.

Omoumi, Ardeshir, Wang, Zihua, Yeow, Vincent, Wu-Chou, Yah-Huei, Chen, Philip K, Ruczinski, Ingo, Cheng, Joanne, Cheah, Felicia SH, Lee, Caroline G, Beaty, Terri H, Chong, Samuel S (December 2013) Fetal polymorphisms at the ABCB1-transporter gene locus are associated with susceptibility to non-syndromic oral cleft malformations. European Journal of Human Genetics, 21 (12). pp. 1436-1441. ISSN 1018-4813

Shi, J., Whyte, W. A., Zepeda-Mendoza, C. J., Milazzo, J. P., Shen, C., Roe, J. S., Minder, J. L., Mercan, F., Wang, E., Eckersley-Maslin, M. A., Campbell, A. E., Kawaoka, S., Shareef, S., Zhu, Z., Kendall, J., Muhar, M., Haslinger, C., Yu, M., Roeder, R. G., Wigler, M. A., Blobel, G. A., Zuber, J., Spector, D. L., Young, R. A., Vakoc, C. R. (November 2013) Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes and Development, 27 (24). pp. 264-273. ISSN 08909369 (ISSN)

Mukhopadhyay, S., Sengupta, A. M. (July 2013) The role of multiple marks in epigenetic silencing and the emergence of a stable bivalent chromatin state. PLoS Computational Biology, 9 (7). e1003121. ISSN 1553-7358 (Electronic)1553-734X (Linking)

Krasnitz, A., Sun, G., Andrews, P., Wigler, M. (June 2013) Target inference from collections of genomic intervals. Proceedings of the National Academy of Sciences of the United States of America, 110 (25). E2271-E2278. ISSN 0027-8424

Donnenberg, A. D., Hicks, J. B., Wigler, M., Donnenberg, V. S. (January 2013) The Cancer Stem Cell: Cell Type or Cell State? Cytometry Part A, 83A (SI 1). pp. 5-7. ISSN 1552-4922

Wigler, M. (October 2012) Broad applications of single-cell nucleic acid analysis in biomedical research. Genome Med, 4 (10). p. 79. ISSN 1756-994X (Electronic)

Stadler, Z. K., Esposito, D., Shah, S., Vijai, J., Yamrom, B., Levy, D., Lee, Y. H., Kendall, J., Leotta, A., Ronemus, M., Hansen, N. , Sarrel, K., Rau-Murthy, R., Schrader, K., Kauff, N., Klein, R., Lipkin, S., Murali, R., Robson, M., Sheinfeld, J., Feldman, D., Bosl, G., Norton, L., Wigler, M., Offit, K. (August 2012) Rare De Novo Germline Copy-Number Variation in Testicular Cancer. The American Journal of Human Genetics, 91 (2). pp. 379-383. ISSN 0002-9297

Kitzing, T., Xue, W., Roessler, S., Krasnitz, A., Schultz, N., Wang, X. W., Wigler, M., Lowe, S. W. (July 2012) Cooperating Tumor Suppressor Genes on Chromosome 8p Predict Survival Outcome in Hepatocellular Carcinoma. European Journal of Cancer, 48. S139-S139. ISSN 0959-8049

Baslan, T., Kendall, J. T., Rodgers, L., Cox, H., Riggs, M., Stepansky, A., Troge, J. E., Ravi, K., Esposito, D., Lakshmi, B., Wigler, M., Navin, N. E., Hicks, J. B. (May 2012) Genome-wide copy number analysis of single cells. Nat Protoc, 7 (6). pp. 1024-41. ISSN 1750-2799 (Electronic)1750-2799 (Linking)

Xue, W., Kitzing, T., Roessler, S., Zuber, J., Krasnitz, A., Schultz, N., Revill, K., Weissmueller, S., Rappaport, A. R., Simon, J., Zhang, J., Luo, W. J., Hicks, J., Zender, L., Wang, X. W., Powers, S., Wigler, M., Lowe, S. W. (May 2012) A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proceedings of the National Academy of Sciences of the United States of America, 109 (21). pp. 8212-8217. ISSN 0027-8424

Iossifov, I., Ronemus, M., Levy, D., Wang, Z. H., Hakker, I., Rosenbaum, J., Yamrom, B., Lee, Y. H., Narzisi, G., Leotta, A., Kendall, J., Grabowska, E., Ma, B. C., Marks, S., Rodgers, L., Stepansky, A., Troge, J., Andrews, P., Bekritsky, M., Pradhan, K., Ghiban, E., Kramer, M., Parla, J., Demeter, R., Fulton, L. L., Fulton, R. S., Magrini, V. J., Ye, K., Darnell, J. C., Darnell, R. B., Mardis, E. R., Wilson, R. K., Schatz, M. C., McCombie, W. R., Wigler, M. (April 2012) De Novo Gene Disruptions in Children on the Autistic Spectrum. Neuron, 74 (2). pp. 285-299. ISSN 0896-6273

Lee, Y. H., Ronemus, M., Kendall, J., Lakshmi, B., Leotta, A., Levy, D., Esposito, D., Grubor, V., Ye, K., Wigler, M., Yamrom, B. (January 2012) Reducing system noise in copy number data using principal components of self-self hybridizations. Proceedings of the National Academy of Sciences of the United States of America, 109 (3). E103-E110. ISSN 0027-8424

Mukhopadhyay, S., Schedl, P., Studitsky, V. M., Sengupta, A. M. (December 2011) Theoretical analysis of the role of chromatin interactions in long-range action of enhancers and insulators. Proceedings of the National Academy of Sciences of the United States of America, 108 (50). pp. 19919-19924. ISSN 0027-8424

Horev, G., Ellegood, J., Lerch, J. P., Son, Y. E., Muthuswamy, L., Vogel, H., Krieger, A. M., Buja, A., Henkelman, R. M., Wigler, M. H., Mills, A. A. (October 2011) Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proceedings of the National Academy of Sciences of the United States of America, 108 (41). pp. 17076-81. ISSN 0027-8424

Menges, F., Narzisi, G., Mishra, B. (September 2011) TotalReCaller: improved accuracy and performance via integrated alignment and base-calling. Bioinformatics, 27 (17). pp. 2330-2337. ISSN 1367-4803

Gilman, S. R, Iossifov, I., Levy, D., Ronemus, M., Wigler, M. H., Vitkup, D. (June 2011) Rare De Novo Variants Associated with Autism Implicate a Large Functional Network of Genes Involved in Formation and Function of Synapses. Neuron, 70 (5). pp. 898-907. ISSN 0896-6273

Levy, D., Ronemus, M., Yamrom, B., Lee, Y. H., Leotta, A., Kendall, J. T., Marks, S., Lakshmi, B., Pai, D., Ye, Kenny, Buja, Andreas, Krieger, Abba, Yoon, S., Troge, J. E., Rodgers,  L., Iossifov, I., Wigler, M. H. (June 2011) Rare De Novo and Transmitted Copy-Number Variation in Autistic Spectrum Disorders. Neuron, 70 (5). pp. 886-897. ISSN 0896-6273

Lee, Yoon-ha, Ronemus, Michael, Kendall, Jude, Lakshmi, B, Leotta, Anthony, Levy, Dan, Esposito, Diane, Grubor, Vladimir, Ye, Kenny, Wigler, Michael, Yamrom, Boris (May 2011) Removing System Noise from Comparative Genomic Hybridization Data by Self-Self Analysis. (Submitted)

Kamalakaran, S., Varadan, V., Giercksky Russnes, H. E., Levy, D., Kendall, J. T., Janevski, A., Riggs, M., Banerjee, N., Synnestvedt, M., Schlichting, E., Kåresen, R., Shama Prasada, K., Rotti, H., Rao, R., Rao, L., Eric Tang, M. H., Satyamoorthy, K., Lucito, R., Wigler, M. H., Dimitrova, N., Naume, B., Borresen-Dale, A. L., Hicks, J. B. (February 2011) DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables. Molecular Oncology, 5 (1). pp. 77-92.

Navin, N. E., Kendall, J. T., Troge, J. E., Andrews, P., Rodgers,  L., McIndoo, J., Cook, K., Stepansky,  A., Levy, D., Esposito, D., Muthuswamy, L., Krasnitz, A., McCombie, W. R., Hicks, J. B., Wigler, M. H. (2011) Tumour evolution inferred by single-cell sequencing. Nature, 472 (7341). pp. 90-94. ISSN 00280836 (ISSN)

Russnes, H. G., Vollan, H. K. M., Lingjærde, O. C., Krasnitz, A., Lundin, P., Naume, B., Sørlie, T., Borgen, E., Rye, I. H., Langerød, A., Chin, S. F., Teschendorff, A. E., Stephens, P. J., Månér, S., Schlichting, E., Baumbusch, L. O., Kåresen, R., Stratton, M. P., Wigler, M. H., Caldas, C., Zetterberg, A., Hicks, J. B., Børresen-Dale, A. L. (June 2010) Genomic architecture characterizes tumor progression paths and fate in breast cancer patients. Science Translational Medicine, 2 (38).

Navin, N. E., Hicks, J. B. (May 2010) Tracing the tumor lineage. Molecular Oncology. ISSN 1878-0261 (Electronic) 1574-7891 (Linking)

Hicks, J. B., Navin, N. E., Kendall, J. T., Levy, D., Wigler, M. H. (May 2010) Tracing Tumor Lineage and Progression through Genomic Copy Number Profiling at the Single Cell Level. Annals of Oncology, 21 (S4). iv49. ISSN 0923-7534

Fonseca, F. V., Ravi, K., Wiseman, D., Tummala, M., Harmon, C., Ryzhov, V., Fineman, J. R., Black, S. M. (March 2010) Mass spectroscopy and molecular modeling predict endothelial nitric oxide synthase dimer collapse by hydrogen peroxide through zinc tetrathiolate metal-binding site disruption. DNA and Cell Biology, 29 (3). pp. 149-160.

Navin, N. E., Krasnitz, A., Rodgers, L., Cook, K., Meth, J. L., Kendall, J. T., Riggs, M., Eberling, Y., Troge, J. E., Grubor, V., Levy, D., Lundin, P., Månér, S., Zetterberg, A., Hicks, J. B., Wigler, M. H. (January 2010) Inferring tumor progression from genomic heterogeneity. Genome Research, 20 (1). pp. 68-80.

Wang, Zihua, Sew, Pui-Hoon, Chong, Samuel S, Lee, Caroline GL (December 2009) Realtime exonuclease-mediated allelic discrimination (READ): a simple homogeneous genotyping assay for SNPs at the ABC gene loci. Pharmacogenomics, 10 (12). pp. 1995-2001. ISSN 1462-2416

Bric, A., Miething, C., Bialucha, C. U., Scuoppo, C., Zender, L., Krasnitz, A., Xuan, Z., Zuber, J., Wigler, M. H., Hicks, J. B., McCombie, W. R., Hemann, M. T., Hannon, G. J., Powers, S., Lowe, S. W. (October 2009) Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model. Cancer Cell, 16 (4). pp. 324-35. ISSN 1535-6108

Hodges, E., Smith, A. D., Kendall, J. T., Xuan, Z., Ravi, K., Rooks, M., Zhang, M. Q., Ye, K., Bhattacharjee, A., Brizuela, L., McCombie, W. R., Wigler, M. H., Hannon, G. J., Hicks, J. B. (September 2009) High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Genome Research, 19 (9). pp. 1593-1605. ISSN 1088-9051

McArthur, H. L., Brogi, E., Patil, S., Wigler, M. H., Norton, L., Hicks, J. B., Hudis, C. A. (September 2009) High resolution microarray copy number analysis (array CGH) suggests that determination of HER2 amplification by FISH (FISH plus ) is inaccurate in human breast cancer specimens that are HER2 2+by immunohistochemistry (IHC2+). European Journal of Cancer Supplements, 7 (2). p. 88. ISSN 1359-6349

Kumar, S., Sun, X., Sharma, S., Aggarwal, S., R., Kandasamy, Fineman, J. R., Black, S. M. (August 2009) GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP. Am J Physiol Lung Cell Mol Physiol, 297 (2). L309-317.

Pang, Grace SY, Wang, Jingbo, Wang, Zihua, Goh, Cynthia, Lee, Caroline GL (July 2009) The G allele of SNP E1/A118G at the µ-opioid receptor gene locus shows genomic evidence of recent positive selection. Pharmacogenomics, 10 (7). pp. 1101-1109. ISSN 1462-2416

Hicks, J. B., McArthur, H., Tan, L. K., Patil, S., Wigler, M. H., Hudis, C., Norton, L. (May 2009) Topo2a and Her2 Co-Amplification Is Uncommon by High Resolution Representational Oligonucleotide Microarray Analysis (Roma) in Human Breast Cancer. Annals of Oncology, 20 (S2). ii22-23. ISSN 0923-7534

Pang, Grace SY, Wang, Jingbo, Wang, Zihua, Lee, Caroline GL (April 2009) Predicting potentially functional SNPs in drug-response genes. Pharmacogenomics, 10 (4). pp. 639-653. ISSN 1462-2416

Wang, Z, Wang, J, Chong, S, Lee, C (March 2009) Mining Potential Functionally Significant Polymorphisms at the ATP-Binding- Cassette Transporter Genes. Current Pharmacogenomics and Personalized Medicine: the international journal for expert reviews in pharmacogenomics, 7 (1). pp. 40-58. ISSN 1875-6921

Russnes, H. G., Vollan, H. K. M., Sorlie, T., Krasnitz, A., Zetterberg, A., Naume, B., Borgen, E., Nesland, J. M., Wigler, M. H., Borresen-Dale, A. L., Hicks, J. B. (March 2009) Molecular subclassification of breast carcinomas based on aCGH reveals two major groups of tumors with common genomic, transcriptomic and clinicopathological characteristics. APMIS, 117 (3). pp. 238-239. ISSN 0903-4641

Mishra, B. (March 2009) Technical perspective: Where biology meets computing. Communications of the ACM, 52 (3). p. 96.

Grubor, V., Krasnitz, A., Troge, J. E., Meth, J. L., Lakshmi, B., Kendall, J. T., Yamrom, B., Alex, G., Pai, D., Navin, N. E., Hufnagel, L. A., Lee, Y. H., Cook, K., Allen, S. L., Rai, K. R., Damle, R. N., Calissano, C., Chiorazzi, N., Wigler, M. H., Esposito, D. (February 2009) Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA). Blood, 113 (6). pp. 1294-1303. ISSN 0006-4971

McArthur, H. L., Tan, L. K., Patil, S., Wigler, M. H., Hudis, C. A., Hicks, J. B., Norton, L. (January 2009) High resolution representational oligonucleotide microarray analysis (ROMA) suggests that TOPO2 and HER2 co-amplification is uncommon in human breast cancer. Cancer Res, 69 (2, Sup). 163S-163S. ISSN 0008-5472

Gupta, L., Kumar, S., Singh, R., Shaik, R., Dimitrova, N., Gorthi, A., Lakshmi, B., Pai, D., Kamalakaran, S., Zhao, X., Wigler, M. H. (December 2008) Classification method for microarray probe selection using sequence, thermodynamics and secondary structure parameters. 19th International Conference on Pattern Recognition. ISSN 1051-4651

Zender, L., Xue, W., Zuber, J., Semighini, C. P., Krasnitz, A., Ma, B., Zender, P., Kubicka, S., Luk, J. M., Schirmacher, P., McCombie, W. R., Wigler, M. H., Hicks, J. B., Hannon, G. J., Powers, S., Lowe, S. W. (November 2008) An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer. Cell, 135 (5). pp. 852-864. ISSN 0092-8674

Grubor, V., Krasnitz, A., Troge, J. E., Meth, J. L., Lakshmi, B., Kendall, J. T., Yamrom, B., Alex, G., Pai, D., Navin, N. E., Hufnagel, L. A., Lee, Y. H., Cook, K., Allen, S. L., Rai, K. R., Damle, R., Calissano, C., Chiorazzi, N., Wigler, M. H., Esposito, D. (November 2008) High-Resolution Array-Based Comparative Genome Hybridization (CGH) Identifies Novel and Recurrent Regions in CLL. Blood, 112 (11). p. 717. ISSN 0006-4971

Kendall, J. T., Lakshmi, B. (August 2008) Quality Assessment for Short Oligonucleotide Microarray Data Comment. Technometrics, 50 (3). pp. 274-276.

Russnes, H. G., Sorlie, T., Krasnitz, A., Zetterberg, A., Naume, B., Borgen, E., Nesland, J. M., Wigler, M. H., Borresen-Dale, A. L., Hicks, J. B. (July 2008) Molecular subclassification of breast carcinomas based on aCGH, gene expression, IHC and ploidy - relevance for clinical outcome. European Journal of Cancer Supplements, 6 (9). p. 9. ISSN 1359-6349

Xue, W., Krasnitz, A., Lucito, R., Sordella, R., Van Aelst, L., Cordon-Cardo, C., Singer, S., Kuehnel, F., Wigler, M. H., Powers, S., Zender, L., Lowe, S. W. (June 2008) DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes & Development, 22 (11). pp. 1439-44. ISSN 0890-9369

Tummala, M., Ryzhov, V., Ravi, K., Black, S. M., Ravi, K. (January 2008) Identification of the cysteine nitrosylation sites in human endothelial nitric oxide synthase. DNA and Cell Biology, 27 (1). pp. 25-33. ISSN 1044-5498

Alarcon, M., Abrahams, B. S., Stone, J. L., Duvall, J. A., Perederiy, J. V., Bomar, J. M., Sebat, J., Wigler, M. H., Martin, C. L., Ledbetter, D. H., Nelson, S. F., Cantor, R. M., Geschwind, D. H. (January 2008) Linkage, Association, and Gene-Expression Analyses Identify CNTNAP2 as an Autism-Susceptibility Gene. Am J Hum Genet, 82 (1). pp. 150-159.

Egan, C. M., Sridhar, S., Wigler, M. H., Hall, I. M. (November 2007) Recurrent DNA copy number variation in the laboratory mouse. Nat Genet, 39 (11). pp. 1384-9. ISSN 1061-4036 (Print)

Lucito, R., Suresh, S., Walter, K., Pandey, A., Lakshmi, B., Krasnitz, A., Sebat, J., Wigler, M. H., Klein, A. P., Brune, K., Palmisano, E., Maitra, A., Goggins, M., Hruban, R. H. (October 2007) Copy-Number Variants in Patients with a Strong Family History of Pancreatic Cancer. Cancer Biol Ther, 6 (10). pp. 1592-9. ISSN 1538-4047 (Print)

Zhao, X., Leotta, A., Kustanovich, V., Lajonchere, C., Geschwind, D. H., Law, K., Law, P., Qiu, S., Lord, C., Sebat, J., Ye, K., Wigler, M. H. (July 2007) A unified genetic theory for sporadic and inherited autism. Proc Natl Acad Sci U S A, 104 (31). pp. 12831-12836. ISSN 0027-8424 (Print)

Wang, Zihua, Wang, Jingbo, Tantoso, Erwin, Wang, Baoshuang, Tai, Amy YP, Ooi, London LPJ, Chong, Samuel S, Lee, Caroline GL (June 2007) Signatures of recent positive selection at the ATP-binding cassette drug transporter superfamily gene loci. Human Molecular Genetics, 16 (11). pp. 1367-1380. ISSN 0964-6906

Sebat, J., Lakshmi, B., Malhotra, D., Troge, J. E., Lese-Martin, C., Walsh, T., Yamrom, B., Yoon, S., Krasnitz, A., Kendall, J. T., Leotta, A., Pai, D., Zhang, R., Lee, Y. H., Hicks, J. B., Spence, S. J., Lee, A. T., Puura, K., Lehtimaki, T., Ledbetter, D., Gregersen, P. K., Bregman, J., Sutcliffe, J. S., Jobanputra, V., Chung, W., Warburton, D., King, M. C., Skuse, D., Geschwind, D. H., Gilliam, T. C., Ye, K., Wigler, M. H. (April 2007) Strong Association of De Novo Copy Number Mutations with Autism. Science, 316 (5823). pp. 445-449.

Black, S. M., Kumar, S., Wiseman, D., Ravi, K., Wedgwood, S., Ryzhov, V., Fineman, J. R. (2007) Pediatric pulmonary hypertension: Roles of endothelin-1 and nitric oxide. Clinical Hemorheology and Microcirculation, 37 (1-2). pp. 111-120. ISSN 1386-0291

Sebat, J., Lakshmi, B., Troge, J., Martin, C., Spence, S., Ledbetter, D., Gilliam, T. C., Ye, K., Geschwind, D., Sutcliffe, J., Wigler, M. H. (December 2006) High-resolution analysis of genome copy number variation in autism. International Journal of Developmental Neuroscience, 24 (8). p. 474. ISSN 0736-5748

Pelham, R. J., Rodgers, L., Hall, I. M., Lucito, R., Nguyen, K. C. Q., Navin, N. E., Hicks, J. B., Mu, D., Powers, S., Wigler, M. H., Botstein, D. (December 2006) Identification of alterations in DNA copy number in host stromal cells during tumor progression. Proc Natl Acad Sci U S A, 103 (52). pp. 19848-19853. ISSN 0027-8424

Hicks, J. B., Krasnitz, A., Lakshmi, B., Navin, N. E., Riggs, M., Leibu, E., Esposito, D., Alexander, J., Troge, J. E., Grubor, V., Yoon, S., Wigler, M. H., Ye, K., Borresen-Dale, A. L., Naume, B., Schlicting, E., Norton, L., Hagerstrom, T., Skoog, L., Auer, G., Månér, S., Lundin, P., Zetterberg, A. (December 2006) Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Research, 16 (12). pp. 1465-79. ISSN 1088-9051

Wang, Zihua, Sew, Pui-Hoon, Ambrose, Helen, Ryan, Stephen, Chong, Samuel S, Lee, Edmund JD, Lee, Caroline GL (December 2006) Nucleotide sequence analyses of the MRP 1 gene in four populations suggest negative selection on its coding region. BMC Genomics, 7 (1). ISSN 1471-2164

Grubor, V. D., Troge, J. E., Meth, J. L., Lakshmi, B., Yamron, B., Hufnagel, L. A., Lee, Y. H., Kendall, J. T., Pai, D., Lee, A., Gregersen, P., Yancopoulos, S., Allen, S., Rai, K. R., Chiorazzi, N., Wigler, M. H., Esposito, D. (November 2006) Genome Analysis of CLL by Representational Oligonucleotide Microarray Analysis (ROMA). ASH Annual Meeting Abstracts, 108 (11). p. 2085.

Navin, N. E., Grubor, V., Hicks, J. B., Leibu, E., Thomas, E., Troge, J., Riggs, M., Lundin, P., Månér, S., Sebat, J., Zetterberg, A., Wigler, M. H. (October 2006) PROBER: oligonucleotide FISH probe design software. Bioinformatics, 22 (19). pp. 2437-8. ISSN 1460-2059 (Electronic)

Lakshmi, B., Hall, I. M., Egan, C., Alexander, J., Leotta, A., Healy, J., Zender, L., Spector, M. S., Xue, W., Lowe, S. W., Wigler, M. H., Lucito, R. (July 2006) Mouse genomic representational oligonucleotide microarray analysis: detection of copy number variations in normal and tumor specimens. Proc Natl Acad Sci U S A, 103 (30). pp. 11234-9. ISSN 0027-8424 (Print)

Zender, L., Spector, M. S., Xue, W., Flemming, P., Cordon-Cardo, C., Silke, J., Fan, S. T., Luk, J. M., Wigler, M. H., Hannon, G. J., Mu, D., Lucito, R., Powers, S., Lowe, S. W. (June 2006) Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell, 125 (7). pp. 1253-67. ISSN 0092-8674 (Print)

West, J., Healy, J., Wigler, M. H., Casey, W., Mishra, B. (January 2006) Validation of S. Pombe sequence assembly by microarray hybridization. J Comput Biol, 13 (1). pp. 1-20. ISSN 1066-5277 (Print)

Sachs, N. A., Holmes, S. E., Cowell, J. K., Conroy, J., Nowak, N. J., McQuaid, D., Rossi, M. R., Gaile, D. P., Christian, S. L., Wigler, M. H., Sebat, J., Ross, C. A., DeLisi, L. E., Margolis, R. L. (September 2005) Assessment of schizophrenia genomes for DNA copy number alterations. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 138B (1). pp. 90-91. ISSN 1552-4841

Wang, Zihua, Wang, Baoshuang, Tang, Kun, Lee, Edmund JD, Chong, Samuel S, Lee, Caroline GL (July 2005) A functional polymorphism within the MRP1 gene locus identified through its genomic signature of positive selection. Human Molecular Genetics, 14 (14). pp. 2075-2087. ISSN 0964-6906

Jobanputra, V., Sebat, J., Troge, J., Chung, W., Anyane-Yeboa, K., Wigler, M. H., Warburton, D. (February 2005) Application of ROMA (representational oligonucleotide microarray analysis) to patients with cytogenetic rearrangements. Genetics in Medicine, 7 (2). pp. 111-118. ISSN 1098-3600

Hicks, J. B., Muthuswamy, L., Krasnitz, A., Navin, N. E., Riggs, M., Grubor, V., Esposito, D., Alexander, J., Troge, J. E., Wigler, M. H., Maner, S., Lundin, P., Zetterberg, A. (2005) High-resolution ROMA CGH and FISH analysis of aneuploid and diploid breast tumors. Cold Spring Harb Symp Quant Biol, 70. pp. 51-63. ISSN 1943-4456 (Electronic) 0091-7451 (Linking)

Bina, M., Wyss, P., Ren, W. H., Szpankowski, W., Thomas, E., Randhawa, R., Reddy, S., John, P. M., Pares-Matos, E. I., Stein, A., Xu, H., Lazarus, S. A. (December 2004) Exploring the characteristics of sequence elements in proximal promoters of human genes. Genomics, 84 (6). pp. 929-940. ISSN 0888-7543

Daruwala, R. S., Rudra, A., Ostrer, H., Lucito, R., Wigler, M. H., Mishra, B. (November 2004) A versatile statistical analysis algorithm to detect genome copy number variation. Proceedings of the National Academy of Sciences of the United States of America, 101 (46). pp. 16292-16297. ISSN 0027-8424

Olshen, A. B., Venkatraman, E. S., Lucito, R., Wigler, M. H. (October 2004) Circular binary segmentation for the analysis of array-based DNA copy number data. Biostatistics, 5 (4). pp. 557-572. ISSN 1465-4644

Sebat, J., Lakshmi, B., Troge, J. E., Alexander, J., Young, J., Lundin, P., Maner, S., Massa, H., Walker, M., Chi, M., Navin, N. E., Lucito, R., Healy, J., Hicks, J. B., Ye, K., Reiner, A., Gilliam, T. C., Trask, B., Patterson, N., Zetterberg, A., Wigler, M. H. (July 2004) Large-scale copy number polymorphism in the human genome. Science, 305 (5683). pp. 525-8. ISSN 1095-9203 (Electronic)

Thomas, E. E., Srebro, N., Sebat, J., Navin, N., Healy, J., Mishra, B., Wigler, M. H. (July 2004) Distribution of short paired duplications in mammalian genomes. Proc Natl Acad Sci U S A, 101 (28). pp. 10349-54. ISSN 0027-8424 (Print)

Healy, J., Thomas, E. E., Schwartz, J. T., Wigler, M. H. (October 2003) Annotating large genomes with exact word matches. Genome Research, 13 (10). pp. 2306-2315. ISSN 1088-9051

Lucito, R., Healy, J., Alexander, J., Reiner, A., Esposito, D., Chi, M. Y., Rodgers, L., Brady, A., Sebat, J., Troge, J. E., West, J. A., Rostan, S., Nguyen, K. C. Q., Powers, S., Ye, K. Q., Olshen, A., Venkatraman, E., Norton, L., Wigler, M. H. (October 2003) Representational oligonucleotide microarray analysis: A high-resolution method to detect genome copy number variation. Genome Research, 13 (10). pp. 2291-2305. ISSN 1088-9051

Cherepinsky, V., Feng, J. W., Rejali, M., Mishra, B. (August 2003) Shrinkage-based similarity metric for cluster analysis of microarray data. Proceedings of the National Academy of Sciences of the United States of America, 100 (17). pp. 9668-9673. ISSN 0027-8424

Mu, D., Chen, L. Y., Zhang, X. P., See, L. H., Koch, C. M., Yen, C., Tong, J. J., Spiegel, L., Nguyen, K. C. Q., Servoss, A., Peng, Y., Pei, L., Marks, J. R., Lowe, S. W., Hoey, T., Jan, L. Y., McCombie, W. R., Wigler, M. H., Powers, S. (March 2003) Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell, 3 (3). pp. 297-302. ISSN 1535-6108

Antoniotti, M., Policriti, A., Ugel, N., Mishra, B. (2003) Model building and model checking for biochemical processes. Cell Biochemistry and Biophysics, 38 (3). pp. 271-286. ISSN 1085-9195

Hamaguchi, M., Meth, J. L., von Klitzing, C., Wei, W., Esposito, D., Rodgers, L., Walsh, T., Welcsh, P., King, M. C., Wigler, M. H. (October 2002) DBC2, a candidate for a tumor suppressor gene involved in breast cancer. Proceedings of the National Academy of Sciences of the United States of America, 99 (21). pp. 13647-13652. ISSN 0027-8424

Wigler, M. H., Mishra, B. (May 2002) Genetics. Wild by nature. Science, 296 (5572). pp. 1407-1408. ISSN 0036-8075

Mishra, B. (January 2002) Comparing genomes. Computing in Science & Engineering, 4 (1). pp. 42-49. ISSN 1521-9615

Stolarov, J., Chang, K., Reiner, A., Rodgers, L., Hannon, G. J., Wigler, M. H., Mittal, V. (November 2001) Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America, 98 (23). pp. 13043-13048. ISSN 0027-8424

Scheffzek, K., Grunewald, P., Wohlgemuth, S., Kabsch, W., Tu, H., Wigler, M. H., Wittinghofer, A., Herrmann, C. (November 2001) The Ras-Byr2RBD complex: Structural basis for Ras effector recognition in yeast. Structure, 9 (11). pp. 1043-1050. ISSN 0969-2126

Wen, S. H., Stolarov, J., Myers, M. P., Su, J. D., Wigler, M. H., Tonks, N. K., Durden, D. L. (April 2001) PTEN controls tumor-induced angiogenesis. Proceedings of the National Academy of Sciences of the United States of America, 98 (8). pp. 4622-4627. ISSN 0027-8424

Lucito, R., West, J., Reiner, A., Alexander, J., Esposito, D., Mishra, B., Powers, S., Norton, L., Wigler, M. H. (November 2000) Detecting gene copy number fluctuations in tumor cells by microarray analysis of genomic representations. Genome Research, 10 (11). pp. 1726-1736. ISSN 1088-9051

Gaasterland, T., Sczyrba, A., Thomas, E., Aytekin-Kurban, G., Gordon, P., Sensen, C. W. (April 2000) MAGPIE/EGRET annotation of the 2.9-Mb Drosophila melanogaster Adh region. Genome Research, 10 (4). pp. 502-510. ISSN 1088-9051

Ronemus, M (December 1999) Stocking stuffers. Nature Genetics, 23 (4). p. 479. ISSN 1061-4036

Mittal, V., Ma, B., Hernandez, N. (July 1999) SNAP(c): a core promoter factor with a built-in DNA-binding damper that is deactivated by the Oct-1 POU domain. Genes & Development, 13 (14). pp. 1807-21. ISSN 0890-9369

Liu, R., Dong, D. L., Sherlock, R., Nestler, H. P., Gennari, C., Mielgo, A., Scolastico, C. (March 1999) Novel reverse-turn mimics inhibit farnesyl transferase. Bioorganic and Medicinal Chemistry Letters , 9 (6). pp. 847-52. ISSN 0960-894X (Print)

Dong, D. L., Liu, R., Sherlock, R., Wigler, M. H., Nestler, H. P. (March 1999) Molecular forceps from combinatorial libraries prevent the farnesylation of Ras by binding to its carboxyl terminus. Chem Biol, 6 (3). pp. 133-41. ISSN 1074-5521 (Print)

Tu, H., Wigler, M. H. (January 1999) Genetic evidence for Pak1 autoinhibition and its release by Cdc42. Mol Cell Biol, 19 (1). pp. 602-11. ISSN 0270-7306 (Print)

Myers, M. P., Pass, I., Batty, I. H., Van der Kaay, J., Stolarov, J. P., Hemmings, B. A., Wigler, M. H., Downes, C. P., Tonks, N. K. (November 1998) The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A, 95 (23). pp. 13513-8. ISSN 0027-8424 (Print)

Henry, R. W., Mittal, V., Ma, B., Kobayashi, R., Hernandez, N. (September 1998) SNAP19 mediates the assembly of a functional core promoter complex (SNAPc) shared by RNA polymerases II and III. Genes and Development, 12 (17). pp. 2664-72. ISSN 08909369 (ISSN)

Webb, C. P., Van Aelst, L., Wigler, M. H., Woude, G. F. (July 1998) Signaling pathways in Ras-mediated tumorigenicity and metastasis. Proc Natl Acad Sci U S A, 95 (15). pp. 8773-8. ISSN 0027-8424 (Print)

Lucito, R., Nakimura, M., West, J. A., Han, Y., Chin, K., Jensen, K. R., McCombie, R. W., Gray, J. W., Wigler, M. H. (April 1998) Genetic analysis using genomic representations. Proceedings of the National Academy of Sciences of the United States of America, 95 (8). pp. 4487-92. ISSN 0027-8424

Hamaguchi, M., O'Connor, E. A., Chen, T., Parnell, L., McCombie, R. W., Wigler, M. H. (March 1998) Rapid isolation of cDNA by hybridization. Proceedings of the National Academy of Sciences of the United States of America, 95 (7). pp. 3764-9. ISSN 0027-8424

Wong, M. W., Henry, R. W., Ma, B., Kobayashi, R., Klages, N., Matthias, P., Strubin, M., Hernandez, N. (January 1998) The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1. Molecular and Cellular Biology, 18 (1). pp. 368-77. ISSN 0270-7306 (Print)

Tu, H., Barr, M., Dong, D. L., Wigler, M. H. (October 1997) Multiple regulatory domains on the Byr2 protein kinase. Mol Cell Biol, 17 (10). pp. 5876-87. ISSN 0270-7306 (Print)

Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., Tonks, N. K. (August 1997) P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A, 94 (17). pp. 9052-7. ISSN 0027-8424 (Print)

Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., Parsons, R. (March 1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 275 (5308). pp. 1943-7. ISSN 0036-8075 (Print)

Barr, M. M., Tu, H., Van Aelst, L., Wigler, M. H. (October 1996) Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe. Mol Cell Biol, 16 (10). pp. 5597-603. ISSN 0270-7306 (Print)

White, M. A., Vale, T., Camonis, J. H., Schaefer, E., Wigler, M. H. (July 1996) A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. J Biol Chem, 271 (28). pp. 16439-42. ISSN 0021-9258 (Print)

Thiagalingam, S., Lisitsyn, N. A., Hamaguchi, M., Wigler, M. H., Willson, J. K., Markowitz, S. D., Leach, F. S., Kinzler, K. W., Vogelstein, B. (July 1996) Evaluation of the FHIT gene in colorectal cancers. Cancer Res, 56 (13). pp. 2936-9. ISSN 0008-5472 (Print)

Khosravi-Far, R., White, M. A., Westwick, J. K., Solski, P. A., Chrzanowska-Wodnicka, M., Van Aelst, L., Wigler, M. H., Der, C. J. (July 1996) Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol Cell Biol, 16 (7). pp. 3923-33. ISSN 0270-7306 (Print)

Joneson, T., White, M. A., Wigler, M. H., Bar-Sagi, D. (February 1996) Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS. Science, 271 (5250). pp. 810-812. ISSN 0036-8075

Xu, H. P., Yanak, B. L., Wigler, M. H., Gorin, M. B. (January 1996) New polymorphic markers in the vicinity of the pearl locus on mouse chromosome 13. Mamm Genome, 7 (1). pp. 16-9. ISSN 0938-8990 (Print)

Marcus, S., Polverino, A., Chang, E., Robbins, D., Cobb, M. H., Wigler, M. H. (June 1995) Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe. Proc Natl Acad Sci U S A, 92 (13). pp. 6180-4. ISSN 0027-8424 (Print)

Jung, V., Chen, L., Hofmann, S. L., Wigler, M. H., Powers, S. (March 1995) Mutations in the SHR5 gene of Saccharomyces cerevisiae suppress Ras function and block membrane attachment and palmitoylation of Ras proteins. Mol Cell Biol, 15 (3). pp. 1333-42. ISSN 0270-7306 (Print)

White, M. A., Nicolette, C., Minden, A., Polverino, A., Van Aelst, L., Karin, M., Wigler, M. H. (February 1995) Multiple Ras functions can contribute to mammalian cell transformation. Cell, 80 (4). pp. 533-41. ISSN 0092-8674 (Print)

Lisitsyn, N. A., Lisitsina, N. M., Dalbagni, G., Barker, P., Sanchez, C. A., Gnarra, J., Linehan, W. M., Reid, B. J., Wigler, M. H. (January 1995) Comparative genomic analysis of tumors: detection of DNA losses and amplification. Proc Natl Acad Sci U S A, 92 (1). pp. 151-5. ISSN 0027-8424 (Print)

Lisitsyn, N., Wigler, M. H. (1995) Representational difference analysis in detection of genetic lesions in cancer. Methods Enzymol, 254. pp. 291-304. ISSN 0076-6879 (Print)

Bolger, G. B., Rodgers, L., Riggs, M. (November 1994) Differential CNS expression of alternative mRNA isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases. Gene, 149 (2). pp. 237-44. ISSN 0378-1119 (Print)

Chang, E. C., Barr, M., Wang, Y., Jung, V., Xu, H. P., Wigler, M. H. (October 1994) Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell, 79 (1). pp. 131-41. ISSN 0092-8674 (Print)

Marcus, S., Polverino, A., Barr, M., Wigler, M. H. (August 1994) Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc Natl Acad Sci U S A, 91 (16). pp. 7762-6. ISSN 0027-8424 (Print)

Jung, V., Wei, W., Ballester, R., Camonis, J., Mi, S., Van Aelst, L., Wigler, M. H., Broek, D. (June 1994) Two types of RAS mutants that dominantly interfere with activators of RAS. Mol Cell Biol, 14 (6). pp. 3707-18. ISSN 0270-7306 (Print)

Marcus, S., Polverino, A., Robbins, D., Cobb, M., Wigler, M. H. (April 1994) Conservation of Ste20-Related Protein-Kinases in Eukaryotes. Faseb Journal, 8 (7). A1431-A1431. ISSN 0892-6638

Milatovich, A., Bolger, G., Michaeli, T., Francke, U. (March 1994) Chromosome Localizations of Genes for 5 Camp-Specific Phosphodiesterases in Man and Mouse. Somatic Cell and Molecular Genetics, 20 (2). pp. 75-86. ISSN 0740-7750

Xu, H. P., White, M., Marcus, S., Wigler, M. H. (January 1994) Concerted action of RAS and G proteins in the sexual response pathways of Schizosaccharomyces pombe. Mol Cell Biol, 14 (1). pp. 50-8. ISSN 0270-7306 (Print)

Lisitsyn, N. A., Segre, J. A., Kusumi, K., Lisitsyn, N. M., Nadeau, J. H., Frankel, W. N., Wigler, M. H., Lander, E. S. (January 1994) Direct isolation of polymorphic markers linked to a trait by genetically directed representational difference analysis. Nat Genet, 6 (1). pp. 57-63. ISSN 1061-4036 (Print)

Lisitsyn, N. A., Leach, F. S., Vogelstein, B., Wigler, M. H. (1994) Detection of genetic loss in tumors by representational difference analysis. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 585-7. ISSN 00917451 (ISSN)

Van Aelst, L., White, M., Wigler, M. H. (1994) Ras partners. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 181-186. ISSN 00917451 (ISSN)

Ohlmeyer, M. H. J., Swanson, R. N., Dillard, L. W., Reader, J. C., Asouline, G., Kobayashi, R., Wigler, M. H., Still, W. C. (December 1993) Complex synthetic chemical libraries indexed with molecular tags. Proceedings of the National Academy of Sciences of the United States of America, 90 (23). pp. 10922-10926. ISSN 0027-8424

Bolger, G., Michaeli, T., Martins, T., St John, T., Steiner, B., Rodgers, L., Riggs, M., Wigler, M. H., Ferguson, K. (October 1993) A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Mol Cell Biol, 13 (10). pp. 6558-71. ISSN 0270-7306 (Print)

Van Aelst, L., Barr, M., Marcus, S., Polverino, A., Wigler, M. H. (July 1993) Complex formation between RAS and RAF and other protein kinases. Proc Natl Acad Sci U S A, 90 (13). pp. 6213-7. ISSN 0027-8424 (Print)

Michaeli, T., Bloom, T. J., Martins, T., Loughney, K., Ferguson, K., Riggs, M., Rodgers, L., Beavo, J. A., Wigler, M. H. (June 1993) Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase- deficient Saccharomyces cerevisiae. Journal of Biological Chemistry, 268 (17). pp. 12925-12932. ISSN 0021-9258

Chardin, P., Camonis, J. H., Gale, N. W., van Aelst, L., Schlessinger, J., Wigler, M. H., Bar-Sagi, D. (May 1993) Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science, 260 (5112). pp. 1338-1343.

Wigler, M. H., Xu, H. P., Vanaelst, L., Jung, V., Marcus, S., Polverino, T., Oneill, K., Chang, E., Camonis, J., Nicolette, C., White, M., Ballester, R. (April 1993) Evolution of Ras Signal Transduction Pathways. Faseb Journal, 7 (7). A1124-A1124. ISSN 0892-6638

Gutmann, D. H., Boguski, M., Marchuk, D., Wigler, M. H., Collins, F. S., Ballester, R. (March 1993) Analysis of the neurofibromatosis type-1 (NF1) GAP-related domain by site-directed mutagenesis. Oncogene, 8 (3). pp. 761-769. ISSN 0950-9232

Lisitsyn, N., Lisitsyn, N., Wigler, M. H. (February 1993) Cloning the differences between two complex genomes. Science, 259 (5097). pp. 946-51. ISSN 0036-8075 (Print)

Neiman, A. M., Stevenson, B. J., Xu, H. P., Sprague, G. F., Herskowitz, I., Wigler, M. H., Marcus, S. (January 1993) Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms. Molecular Biology of the Cell, 4 (1). pp. 107-120. ISSN 1059-1524

Andersen, L. B., Ballester, R., Marchuk, D. A., Chang, E., Gutmann, D. H., Saulino, A. M., Camonis, J., Wigler, M. H., Collins, F. S. (January 1993) A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity. Molecular and Cellular Biology, 13 (1). pp. 487-495. ISSN 0270-7306

Jung, V., Pestka, S. B., Pestka, S. (1993) Cloning of polymerase chain reaction-generated DNA containing terminal restriction endonuclease recognition sites. Methods Enzymol, 218. pp. 357-62. ISSN 0076-6879 (Print)

Marcus, S., Wigler, M. H., Xu, H. P., Ballester, R., Kawamukai, M., Polverino, A. (1993) RAS function and protein kinase cascades. Ciba Found Symp, 176. 53-61; discussion 61. ISSN 0300-5208 (Print)

Shibuya, E. K., Polverino, A. J., Chang, E., Wigler, M. H., Ruderman, J. V. (October 1992) Oncogenic Ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America, 89 (20). pp. 9831-9835. ISSN 0027-8424

Xu, H. P., Rajavashisth, T., Grewal, N., Jung, V., Riggs, M., Rodgers, L., Wigler, M. H. (July 1992) A gene encoding a protein with seven zinc finger domains acts on the sexual differentiation pathways of Schizosaccharomyces pombe. Mol Biol Cell, 3 (7). pp. 721-34. ISSN 1059-1524 (Print)

Gerst, J. E., Rodgers, L., Riggs, M., Wigler, M. (May 1992) SNC1, a yeast homolog of the synaptic vesicle-associated membrane protein/synaptobrevin gene family: genetic interactions with the RAS and CAP genes. Proc Natl Acad Sci U S A, 89 (10). pp. 4338-42. ISSN 0027-8424 (Print)0027-8424 (Linking)

Lei, K. J., Gluzman, Y., Pan, C. J., Chou, J. Y. (May 1992) Immortalization of Virus-Free Human Placental Cells That Express Tissue-Specific Functions. Molecular Endocrinology, 6 (5). pp. 703-712. ISSN 0888-8809

Maulbecker, C., Mohr, I., Gluzman, Y., Bartholomew, J., Botchan, M. (April 1992) A deletion in the simian virus 40 large T antigen impairs lytic replication in monkey cells in vivo but enhances DNA replication in vitro: new complementation function of T antigen. J Virol, 66 (4). pp. 2195-207. ISSN 0022-538X (Print)0022-538X (Linking)

Kawamukai, M., Gerst, J., Field, J., Riggs, M., Rodgers, L., Wigler, M. H., Young, D. (February 1992) Genetic and biochemical analysis of the adenylyl cyclase-associated protein, cap, in Schizosaccharomyces pombe. Molecular Biology of the Cell, 3 (2). pp. 167-180. ISSN 1059-1524

Andersen, L., Ballester, R., Marchuk, D., Saulino, A., Wigler, M. H., Collins, F. (October 1991) Alternative Splicing in the Proposed Catalytic Domain of the Type-1 Neurofibromatosis Gene. American Journal of Human Genetics, 49 (4). p. 21. ISSN 0002-9297

Vojtek, A., Haarer, B., Field, J., Gerst, J., Pollard, T. D., Brown, S., Wigler, M. H. (August 1991) Evidence for a functional link between profilin and CAP in the yeast S. cerevisiae. Cell, 66 (3). pp. 497-505. ISSN 0092-8674

Daar, I., Nebreda, A. R., Yew, N., Sass, P., Paules, R., Santos, E., Wigler, M. H., Vandewoude, G. F. (July 1991) The Ras Oncoprotein and M-Phase Activity. Science, 253 (5015). pp. 74-76. ISSN 0036-8075

Wang, Y., Xu, H. P., Riggs, M., Rodgers, L., Wigler, M. H. (July 1991) byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype. Molecular & Cellular Biology, 11 (7). pp. 3554-63. ISSN 0270-7306

Young, D., O'Neill, K., Broek, D., Wigler, M. H. (June 1991) The adenylyl cyclase-encoding gene from Saccharomyces kluyveri. Gene, 102 (1). pp. 129-32. ISSN 0378-1119

Colicelli, J., Nicolette, C., Birchmeier, C., Rodgers, L., Riggs, M., Wigler, M. H. (April 1991) Expression of three mammalian cDNAs that interfere with RAS function in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A, 88 (7). pp. 2913-7. ISSN 0027-8424

Zoller, M. J., Yonemoto, W., Taylor, S. S., Johnson, K. E. (March 1991) Mammalian cAMP-dependent protein kinase functionally replaces its homolog in yeast. Gene, 99 (2). pp. 171-9. ISSN 0378-1119 (Print)0378-1119 (Linking)

Gerst, J. E., Ferguson, K., Vojtek, A., Wigler, M. H., Field, J. (March 1991) CAP is a bifunctional component of the Saccharomyces cerevisiae adenylyl cyclase complex. Molecular & Cellular Biology, 11 (3). pp. 1248-57. ISSN 0270-7306

Kawamukai, M., Ferguson, K., Wigler, M. H., Young, D. (February 1991) Genetic and biochemical analysis of the adenylyl cyclase of Schizosaccharomyces pombe. Cell Regulation, 2 (2). pp. 155-64. ISSN 1044-2030

Rindi, G., Efrat, S., Ghatei, M. A., Bloom, S. R., Solcia, E., Polak, J. M. (1991) Glucagonomas of transgenic mice express a wide range of general neuroendocrine markers and bioactive peptides. Virchows Arch A Pathol Anat Histopathol, 419 (2). pp. 115-29. ISSN 0174-7398 (Print)0174-7398 (Linking)

Heisermann, G. J., Gill, G. N. (1991) Identification of phosphorylation sites: use of the epidermal growth factor receptor. Methods in Enzymology, 198. pp. 233-241. ISSN 0076-6879

Vojtek, A., Field, J., Gerst, J., Wigler, M. H. (1991) The Ras Signalling Pathway in Yeast. Journal of Cellular Biochemistry - Supplement.(15 PART B). p. 84.

Wigler, M. H., Ballester, R., Chang, E., Colicelli, J., Field, J., Gerst, J., Kawamukai, M., Michaeli, T., Nicolette, C. (1991) The Ways of Ras. Proceedings American Association for Cancer Research Annual Meeting. p. 435.

Wang, Y., Boguski, M., Riggs, M., Rodgers, L., Wigler, M. (1991) sar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1. Cell Regulation, 2 (6). pp. 453-465. ISSN 10442030 (ISSN)

Ballester, R., Marchuk, D., Boguski, M., Saulino, A., Letcher, R., Wigler, M. H., Collins, F. (November 1990) The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell, 63 (4). pp. 851-9. ISSN 0092-8674

Romani, M., Deambrosis, A., Alhadeff, B., Purrello, M., Gluzman, Y., Siniscalco, M. (November 1990) Preferential integration of the Ad5/SV40 hybrid virus at the highly recombinogenic human chromosomal site 1p36. Gene, 95 (2). pp. 231-241. ISSN 0378-1119

Xu, H. P., Wang, Y., Riggs, M., Rodgers, L., Wigler, M. H. (September 1990) Biological activity of the mammalian RAP genes in yeast. Cell Regulation, 1 (10). pp. 763-769. ISSN 1044-2030

Wigler, M. H. (August 1990) Oncoproteins. Gaps in Understanding Ras. Nature, 346 (6286). pp. 696-697. ISSN 0028-0836

Colicelli, J., Field, J., Ballester, R., Chester, N., Young, D., Wigler, M. H. (June 1990) Mutational mapping of RAS-responsive domains of the Saccharomyces cerevisiae adenylyl cyclase. Molecular & Cellular Biology, 10 (6). pp. 2539-43. ISSN 0270-7306

Field, J., Vojtek, A., Ballester, R., Bolger, G., Colicelli, J., Ferguson, K., Gerst, J., Kataoka, T., Michaeli, T., Powers, S., Riggs, M., Rodgers, L., Wieland, I., Wheland, B., Wigler, M. H. (April 1990) Cloning and characterization of CAP, the S. cerevisiae gene encoding the 70 kd adenylyl cyclase-associated protein. Cell, 61 (2). pp. 319-327. ISSN 0092-8674

Wieland, I., Bolger, G., Asouline, G., Wigler, M. H. (April 1990) A method for difference cloning: gene amplification following subtractive hybridization. Proc Natl Acad Sci U S A, 87 (7). pp. 2720-4. ISSN 0027-8424

Levin, L. R., Zoller, M. J. (March 1990) Association of catalytic and regulatory subunits of cyclic AMP-dependent protein kinase requires a negatively charged side group at a conserved threonine. Mol Cell Biol, 10 (3). pp. 1066-75. ISSN 0270-7306 (Print)0270-7306 (Linking)

Field, J., Xu, H. P., Michaeli, T., Ballester, R., Sass, P., Wigler, M. H., Colicelli, J. (January 1990) Mutations of the adenylyl cyclase gene that block RAS function in Saccharomyces cerevisiae. Science, 247 (4941). pp. 464-7. ISSN 0036-8075

Birchmeier, C., O'Neill, K., Riggs, M., Wigler, M. H. (1990) Characterization of Ros1 cDNA from a Human Glioblastoma Cell Line. Proceedings of the National Academy of Sciences of the United States of America, 87 (12). pp. 4799-4803.

Ballester, R., Wigler, M. H. (1990) Isolation and Characterization of Genes That Regulate Ras Function in the Yeast Saccharomyces-Cerevisiae. Yeast, 6 (SPEC. ). S212.

Gerst, J. E., Field, J., Ferguson, K., Wigler, M. H. (1990) Molecular and Phenotypic Analysis of Cap a Regulatory Element Involved in Mediating Both Ras Action and Amino Acid Balance. Yeast, 6 (SPEC. ). S174.

Field, J., Colicelli, J., Vojtek, A., Ballester, R., Ferguson, K., Chester, N., Michaeli, T., Gerst, J., Riggs, M. (1990) Ras from the Yeast Perspective. Journal of Cellular Biochemistry, 44 (S14C). p. 124.

Xu, H. P., Riggs, M., Rodgers, L., Wigler, M. H. (1990) A gene from Schizosaccharomyces-Pombe with homology to Escherichia-Coli RNAse III blocks conjugation and sporulation when overexpressed in wild type cells. Nucleic Acids Research, 18 (17). p. 5304.

Ballester, R., Michaeli, T., Ferguson, K., Xu, H. P., McCormick, F., Wigler, M. H. (November 1989) Genetic analysis of mammalian GAP expressed in yeast. Cell, 59 (4). pp. 681-6. ISSN 0092-8674

Michaeli, T., Field, J., Ballester, R., O'Neill, K., Wigler, M. H. (October 1989) Mutants of H-ras that interfere with RAS effector function in Saccharomyces cerevisiae. Embo J, 8 (10). pp. 3039-44. ISSN 0261-4189

Young, D., Riggs, M., Field, J., Vojtek, A., Broek, D., Wigler, M. H. (October 1989) The adenylyl cyclase gene from Schizosaccharomyces pombe. Proc Natl Acad Sci U S A, 86 (20). pp. 7989-93. ISSN 0027-8424

Colicelli, J., Birchmeier, C., Michaeli, T., O'Neill, K., Riggs, M., Wigler, M. H. (May 1989) Isolation and characterization of a mammalian gene encoding a high-affinity cAMP phosphodiesterase. Proc Natl Acad Sci U S A, 86 (10). pp. 3599-603. ISSN 0027-8424

Powers, S., O'Neill, K., Wigler, M. H. (February 1989) Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae. Molecular & Cellular Biology, 9 (2). pp. 390-5. ISSN 0270-7306

Sharma, S., Birchmeier, C., Nikawa, J., O'Neill, K., Rodgers, L., Wigler, M. H. (1989) Characterization of the ros1-gene products expressed in human glioblastoma cell lines. Oncogene Res, 5 (2). pp. 91-100. ISSN 0890-6467

Young, D., O'Neill, K., Jessell, T., Wigler, M. H. (July 1988) Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain. Proc Natl Acad Sci U S A, 85 (14). pp. 5339-42. ISSN 0027-8424

Cameron, S., Levin, L., Zoller, M., Wigler, M. H. (May 1988) cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae. Cell, 53 (4). pp. 555-66. ISSN 0092-8674

Field, J., Nikawa, J., Broek, D., MacDonald, B., Rodgers, L., Wilson, I. A., Lerner, R. A., Wigler, M. H. (May 1988) Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Molecular & Cellular Biology, 8 (5). pp. 2159-65. ISSN 0270-7306

Toda, T., Cameron, S., Sass, P., Wigler, M. H. (May 1988) SCH9, a gene of Saccharomyces cerevisiae that encodes a protein distinct from, but functionally and structurally related to, cAMP-dependent protein kinase catalytic subunits. Genes Dev, 2 (5). pp. 517-27. ISSN 0890-9369

Levin, L. R., Kuret, J., Johnson, K. E., Powers, S., Cameron, S., Michaeli, T., Wigler, M. H., Zoller, M. J. (April 1988) A mutation in the catalytic subunit of cAMP-dependent protein kinase that disrupts regulation. Science, 240 (4848). pp. 68-70.

Wigler, M. H., Cameron, S., Powers, S., Field, J., Toda, T., Broek, D., Nikawa, J., Michaelis, T., Colicelli, J. (1988) Integration of Ras and Adenylate Cyclase Pathways in Yeast. Journal of Cell Biology, 107 (6 PART). 4A.

Wigler, M. H., Field, J., Powers, S., Broek, D., Toda, T., Cameron, S., Nikawa, J., Michaeli, T., Colicelli, J., Ferguson, K. (1988) Studies of RAS function in the yeast Saccharomyces cerevisiae. Cold Spring Harbor Symposia on Quantitative Biology, 53 (2). pp. 649-55. ISSN 00917451 (ISSN)

Birchmeier, C., Sharma, S., Wigler, M. H. (December 1987) Expression and rearrangement of the ROS1 gene in human glioblastoma cells. Proc Natl Acad Sci U S A, 84 (24). pp. 9270-4. ISSN 0027-8424

Nikawa, J., Cameron, S., Toda, T., Ferguson, K. M., Wigler, M. H. (November 1987) Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae. Genes & Development, 1 (9). pp. 931-937.

Nikawa, J., Sass, P., Wigler, M. H. (October 1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Molecular & Cellular Biology, 7 (10). pp. 3629-36. ISSN 0270-7306

Rabin, M., Birnbaum, D., Young, D., Birchmeier, C., Wigler, M. H., Ruddle, F. H. (July 1987) Human ROS1 and MAS1 oncogenes located in regions of chromosome 6 associated with tumor-specific rearrangements. Oncogene Res, 1 (2). pp. 169-78. ISSN 0890-6467 (Print)

Toda, T., Cameron, S., Sass, P., Zoller, M., Scott, J. D., McMullen, B., Hurwitz, M., Krebs, E. G., Wigler, M. H. (April 1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Molecular & Cellular Biology, 7 (4). pp. 1371-1377.

Broek, D., Toda, T., Michaeli, T., Levin, L., Birchmeier, C., Zoller, M., Powers, S., Wigler, M. H. (March 1987) The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell, 48 (5). pp. 789-800.

Johnson, K. E., Cameron, S., Toda, T., Wigler, M. H., Zoller, M. J. (1987) Expression in Escherichia coli of BCY1, the regulatory subunit of cyclic AMP-dependent protein kinase from Saccharomyces cerevisiae. Journal of Biological Chemistry, 262 (18). pp. 8636-8642.

Field, J., Broek, D., Kataoka, T., Wigler, M. H. (1987) Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae. Molecular & Cellular Biology, 7 (6). pp. 2128-2133.

Toda, T., Cameron, S., Sass, P., Zoller, M., Wigler, M. H. (1987) Three different genes in Saccharomyces cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell, 50 (2). pp. 277-288.

Michaelis, S., Anna, S. S., Powers, S., Wigler, M. H., Herskowitz, I. (1987) Yeast Mating Pheromone a-Factor and Its Relationship to Ras Proteins. Journal of Cellular Biochemistry. p. 261. ISSN 0730-2312

Herlands, L., Kishimoto, T., Birchmeier, C., Wigler, M. H., Koide, S. S. (December 1986) Induction of Oocyte Maturation by Injection of Oncogenic H-Ras Protein in the Starfish. Zoological Science, 3 (6). p. 1036. ISSN 0289-0003

Birchmeier, C., Young, D., Wigler, M. H. (June 1986) Characterization of two new human oncogenes. Cold Spring Harbor Symposia on Quantitative Biology, 51 (2). pp. 993-1000. ISSN 00917451 (ISSN)

Birchmeier, C., Birnbaum, D., Waitches, G., Fasano, O., Wigler, M. H. (1986) Characterization of an activated human ros gene. Molecular & Cellular Biology, 6 (9). pp. 3109-3116.

Sass, P., Field, J., Nikawa, J., Toda, T., Wigler, M. H. (1986) Cloning and characterization of the high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 83 (24). pp. 9303-9307.

Young, D., Waitches, G., Birchmeier, C., Fasano, O., Wigler, M. H. (1986) Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains. Cell, 45 (5). pp. 711-720.

Powers, S., Michaelis, S., Broek, D., Ann-A, S. S., Field, J., Herskowitz, I., Wigler, M. H. (1986) RAM, a gene of yeast required for a functional modification of RAS proteins and for production of mating pheromone a-factor. Cell, 47 (3). pp. 413-422.

Kataoka, T., Broek, D., Wigler, M. H. (December 1985) DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase. Cell, 43 (2). pp. 493-505. ISSN 0092-8674

Birchmeier, C., Broek, D., Wigler, M. H. (December 1985) RAS proteins can induce meiosis in Xenopus oocytes. Cell, 43 (3 PART). pp. 615-622.

Sambrook, J, Rodgers, L, White, J, Gething, MJ (January 1985) Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin. The EMBO Journal, 4 (1). pp. 91-103. ISSN 0261-4189

Birchmeier, C., Broek, D., Toda, T., Powers, S., Kataoka, T., Wigler, M. H. (1985) Conservation and divergence of RAS protein function during evolution. Cold Spring Harbor Symposia on Quantitative Biology, 50. pp. 721-725. ISSN 00917451 (ISSN)

Powers, S., Kataoka, T., Toda, T., Fasano, O., Wigler, M. H. (1985) Control of Yeast Adenyl-Cyclase by Ras Proteins. Federation Proceedings, 44 (3). R8-R8. ISSN 0014-9446

Broek, D., Samily, N., Fasano, O., Fujiyama, A., Tamanoi, F., Northup, J., Wigler, M. H. (1985) Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins. Cell, 41 (3). pp. 763-770.

Kataoka, T., Powers, S., Cameron, S., Fasano, O., Goldfarb, M., Broach, J., Wigler, M. H. (1985) Functional homology of mammalian and yeast RAS genes. Cell, 40 (1). pp. 19-26.

Toda, T., Uno, I., Ishikawa, T., Powers, S., Kataoka, T., Broek, D., Cameron, S., Broach, J., Matsumoto, K., Wigler, M. H. (1985) In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell, 40 (1). pp. 27-36.

Feramisco, J., Sullivan, N., Kamata, T., Barsagi, D., Welch, W., Gross, M., Sweet, R., Rosenberg, M., Sathe, G., Fasano, O., Goldfarb, M., Wigler, M. H., Nitecki, D., Clark, R., Arnheim, N., McCormick, F. (1985) Microinjection of Ras Oncogene Proteins and Inhibitory Antibodies Specific for the Ras Oncogene Proteins into Living Normal and Transformed-Cells. Federation Proceedings, 44 (5). p. 1768. ISSN 0014-9446

Gross, M., Sweet, R. W., Sathe, G., Yokoyama, S., Fasano, O., Goldfarb, M., Wigler, M. H., Rosenberg, M. (1985) Purification and characterization of human H-RAS proteins expressed in Escherichia coli. Molecular and Cellular Biology, 5 (5). pp. 1015-1024. ISSN 0270-7306

Broach, J., Toda, T., Kataoka, T., Powers, S., Broek, D., Wigler, M. H. (1985) Ras Proteins Function Exclusively to Modulate Adenylate-Cyclase Activity in the Yeast Saccharomyces. DNA-a Journal of Molecular & Cellular Biology, 4 (1). p. 64. ISSN 0198-0238

Stillman, B. W., Gluzman, Y. (1985) Replication and Supercoiling of Sv-40 DNA in Cell Extracts from Human Cells. Molecular & Cellular Biology, 5 (8). pp. 2051-2060.

Fasano, O., Birnbaum, D., Edlund, L., Fogh, J., Wigler, M. H. (September 1984) New human transforming genes detected by a tumorigenicity assay. Molecular & Cellular Biology, 4 (9). pp. 1695-1705.

Kataoka, T., Powers, S., McGill, C., Fasano, O., Strathern, J., Broach, J., Wigler, M. H. (June 1984) Genetic analysis of yeast RAS1 and RAS2 genes. Cell, 37 (2). pp. 437-445. ISSN 0092-8674

Powers, S., Kataoka, T., Fasano, O., Goldfarb, M., Strathern, J., Broach, J., Wigler, M. H. (March 1984) Genes in Saccharomyces cerevisiae encoding proteins with domains homologous to the mammalian ras proteins. Cell, 36 (3). pp. 607-612.

Fasano, O., Aldrich, T., Tamanoi, F., Taparowsky, E., Furth, M., Wigler, M. H. (1984) Analysis of the transforming potential of the human H-ras gene by random mutagenesis. Proceedings of the National Academy of Sciences of the United States of America, 81 (13). pp. 4008-4012.

Wigler, M. H., Fasano, O., Taparowsky, E., Birnbaum, D., Goldfarb, M., Fogh, J. (1984) Human Transforming Genes. DNA-a Journal of Molecular & Cellular Biology, 3 (1). p. 65. ISSN 0198-0238

Meyers, D. A., Antonarakis, S. E., Fearon, E. R., Mallonee, R. L., Waber, P. G., Phillips, J. A., Kazazian, H. H., Levine, M., Kronenberg, H. M., Wigler, M. H., Ullrich, A. (1984) Use of DNA Polymorphisms to Establish the Linkage Map of the Pth, Beta-Globin, C-Ha-Ras-1, and Insulin Loci on 11p. Cytogenetics and Cell Genetics, 37 (1-4). pp. 540-541. ISSN 0301-0171

Tamanoi, F., Walsh, M., Kataoka, T., Wigler, M. H. (1984) A product of yeast RAS-2 gene is a guanine nucleotide binding protein. Proceedings of the National Academy of Sciences of the United States of America, 81 (22). pp. 6924-6928.

Barker, D., McCoy, M., Weinberg, R., Goldfarb, M., Wigler, M. H., Burt, R., Gardner, E., White, R. (September 1983) A test of the role of two oncogenes in inherited predisposition to colon cancer. Mol Biol Med, 1 (2). pp. 199-206. ISSN 0735-1313 (Print)

Shimizu, K., Birnbaum, D., Ruley, M. A., Fasano, O., Suard, Y., Edlund, L., Taparowsky, E., Goldfarb, M., Wigler, M. H. (August 1983) Structure of the Ki-Ras Gene of the Human-Lung Carcinoma Cell-Line Calu-1. Nature, 304 (5926). pp. 497-500. ISSN 0028-0836

Shimizu, K., Goldfarb, M., Suard, Y., Perucho, M., Li, Y., Kamata, T., Feramisco, J., Stavnezer, E., Fogh, J., Wigler, M. H. (April 1983) Three human transforming genes are related to the viral ras oncogenes. Proceedings of the National Academy of Sciences of the United States of America, 80 (8). pp. 2112-2116. ISSN 0027-8424

Shimizu, K., Goldfarb, M., Perucho, M., Wigler, M. H. (January 1983) Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line. Proc Natl Acad Sci U S A, 80 (2). pp. 383-387.

Ryan, J., Barker, P. E., Shimizu, K., Wigler, M. H., Ruddle, F. H. (1983) Chromosomal Assignment of a Family of Human Oncogenes. Proc Natl Acad Sci U S A, 80 (14). pp. 4460-4463. ISSN 0027-8424

Wigler, M. H., Shimizu, K., Goldfarb, M., Taparowsky, E., Suard, Y., Fasano, O. (1983) Human Transforming Genes. DNA-a Journal of Molecular & Cellular Biology, 2 (1). p. 64. ISSN 0198-0238

Kwoh, T. J., Zipser, D., Wigler, M. H. (1983) Mutational analysis of the cloned chicken thymidine kinase gene. J Mol Appl Genet, 2 (2). pp. 191-200. ISSN 0271-6801 (Print)

Fasano, O., Taparowsky, E., Fiddes, J., Wigler, M. H., Goldfarb, M. (1983) Sequence and Structure of the Coding Regions of the Human H-Ras-1 Gene from T-24 Bladder Carcinoma Cells. Journal of Molecular & Applied Genetics, 2 (2). pp. 173-180. ISSN 0271-6801

Taparowsky, E., Shimizu, K., Goldfarb, M., Wigler, M. H. (1983) Structure and Activation of the Human N-Ras Gene. Cell, 34 (2). pp. 581-586.

Shimizu, K., Taparowsky, E., Fasano, O., Suard, Y., Birnbaum, D., Ruley, M. A., Goldfarb, M., Wigler, M. H. (1983) Structures of 3 Ras Genes Activated in Human-Tumor Cell-Lines. Journal of Cell Biology, 97 (5). A69-A69. ISSN 0021-9525

Taparowsky, E., Suard, Y., Fasano, O., Shimizu, K., Goldfarb, M., Wigler, M. H. (1982) Activation of the T24 Bladder-Carcinoma Transforming Gene Is Linked to a Single Amino-Acid Change. Nature, 300 (5894). pp. 762-765. ISSN 0028-0836

Goldfarb, M., Shimizu, K., Perucho, M., Wigler, M. H. (1982) Isolation and Preliminary Characterization of a Human Transforming Gene from T24 Bladder-Carcinoma Cells. Nature, 296 (5856). pp. 404-409. ISSN 0028-0836

Perucho, M., Goldfarb, M., Shimizu, K., Lama, C., Fogh, J., Wigler, M. H. (December 1981) Human-tumor-derived cell lines contain common and different transforming genes. Cell, 27 (3 Pt 2). pp. 467-76. ISSN 0092-8674

Perucho, M., Wigler, M. H. (1981) Linkage and expression of foreign DNA in cultured animal cells. Cold Spring Harb Symp Quant Biol, 45 (2). pp. 829-838. ISSN 0091-7451 (Print)0091-7451 (Linking)

Wigler, M. H. (1981) The inheritance of methylation patterns in vertebrates. Cell, 24 (2). pp. 285-286.

Wigler, M. H., Levy, D., Perucho, M. (1981) The somatic replication of DNA methylation. Cell, 24 (1). pp. 33-40.

Hanahan, D., Lane, D., Lipsich, L., Wigler, M. H., Botchan, M. (August 1980) Characteristics of an Sv40-Plasmid Recombinant and Its Movement into and out of the Genome of a Murine Cell. Cell, 21 (1). pp. 127-139. ISSN 0092-8674

Wigler, M. H., Perucho, M., Kurtz, D., Dana, S., Pellicer, A., Axel, R., Silverstein, S. (June 1980) Transformation of mammalian cells with an amplifiable dominant acting gene. Proceedings of the National Academy of Sciences of the United States of America, 77 (6). pp. 3567-3570. ISSN 0027-8424

Perucho, M., Hanahan, D., Lipsich, L., Wigler, M. H. (May 1980) Isolation of the chicken thymidine kinase gene by plasmid rescue. Nature, 285 (5762). pp. 207-210.

Klessig, D. F., Wigler, M. H., Grodzicker, T. (1980) Construction of Co Transformation of Human Cell Lines Which Express Segments of the Adenovirus Genome. Journal of Supramolecular Structure, 9 (SUPPL.). p. 256.

Wigler, M. H., Perucho, M., Lipsich, L., Lane, D., Klessig, D., Grodzicker, T., Botchan, M., Hanahan, D. (1980) DNA Mediated Gene Transfer: Theory and Application. Journal of Supramolecular Structure, 9 (SUPPL.). p. 229. ISSN 0161-3294

Perucho, M., Hanahan, D., Wigler, M. H. (1980) Genetic and Physical Linkage of Exogenous Sequences in Transformed-Cells. Cell, 22 (1). pp. 309-317. ISSN 0092-8674

Wold, B., Wigler, M. H., Lacy, E., Maniatis, T., Silverstein, S., Axel, R. (November 1979) Introduction and expression of a rabbit Beta-globin gene in mouse fibroblasts. Proceedings of the National Academy of Sciences of the United States of America, 76 (11). pp. 5684-5688. ISSN 0027-8424

Wigler, M. H., Pellicer, A., Silverstein, S., Axel, R., Urlaub, G., Chasin, L. (March 1979) DNA-Mediated Transfer of the Adenine Phosphoribosyltransferase Locus into Mammalian Cells. Proc Natl Acad Sci U S A, 76 (3). pp. 1373-1376.

Wigler, M. H., Sweet, R., Sim, G. K., Wold, B., Pellicer, A., Lacy, E., Maniatis, T., Silverstein, S., Axel, R. (1979) Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell, 16 (4). pp. 777-785. ISSN 0092-8674

Wigler, M. H., Pellicer, A., Silverstein, S., Axel, R. (July 1978) Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor. Cell, 14 (3). pp. 725-731.

Wigler, M. H., DeFeo, D., Weinstein, I. B. (May 1978) Induction of Plasminogen Activator in Cultured Cells by Macrocyclic Plant Diterpene Esters and Other Agents Related to Tumor Promotion. Cancer Res, 38 (5). pp. 1434-1437.

Pellicer, A., Wigler, M. H., Axel, R., Silverstein, S. (1978) The transfer and stable integration of HSV thymidine kinase gene into mouse cells. Cell, 14 (1). pp. 133-141. ISSN 0092-8674

Weinstein, I. B., Wigler, M. H. (December 1977) Cell culture studies provide new information on tumour promoters. Nature, 270 (5639). pp. 659-550.

Wigler, M. H., Silverstein, S., Lee, L. S., Pellicer, A., Cheng, Y. C., Axel, R. (1977) Transfer of Purified Herpes-Virus Thymidine Kinase Gene to Cultured Mouse Cells. Cell, 11 (1). pp. 223-232. ISSN 0092-8674

Wigler, M. H., Axel, R. (1976) Nucleosomes in metaphase chromosomes. Nucleic Acids Res, 3 (6). pp. 1463-1461.

Wigler, M. H., Weinstein, I. B. (1976) Tumor Promotor Induces Plasminogen Activator. Nature, 259 (5540). pp. 232-233. ISSN 0028-0836

Wigler, M. H., Weinstein, I. B. (1975) Preparative Method for Obtaining Enucleated Mammalian-Cells. Biochemical and Biophysical Research Communications, 63 (3). pp. 669-674. ISSN 0006-291X

Book Section

Wigler, MH (January 2017) The ras system in yeasts. In: The ras Superfamily of GTPases. CRC Press, pp. 155-172. ISBN 9781138105126

Narzisi, G., Mishra, B., Schatz, M. C. (2014) On algorithmic complexity of biomolecular sequence assembly problem. In: Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Springer, pp. 183-195. ISBN 16113349 - ISSN978-331907952-3

Mishra, B. (2003) Life's duplicities: Sex, death, and Valis. In: High Performance Computing - HiPC 2003. Lecture Notes in Computer Science, 2913 . Springer-Verlag Berlin, Berlin, p. 1. ISBN 978-3-540-20626-2

Casey, Will, Mishra, Bud (2003) A Nearly Linear-Time General Algorithm for Genome-Wide Bi-allele Haplotype Phasing. In: High Performance Computing - HiPC 2003. Lecture Notes in Computer Science, 2913 . Springer Berlin Heidelberg, pp. 204-215. ISBN 978-3-540-20626-2

Lucito, R., Wigler, M. H. (2003) Preparation of slides and hybridization. In: DNA microarrays : a molecular cloning manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 394-399. ISBN 0879696257

Lucito, R., Wigler, M. H. (2003) Preparation of target DNA. In: DNA microarrays : a molecular cloning manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 386-393. ISBN 0879696257

Mishra, B. (2002) A symbolic approach to modeling cellular behavior. In: High Performance Computing — HiPC 2002. Lecture Notes in Computer Science, 2552 . Springer, pp. 725-732. ISBN 0302-9743

Casey, W., Mishra, B., Wigler, M. H. (2001) Placing Probes along the Genome Using Pairwise Distance Data. In: Algorithms in Bioinformatics: First International Workshop, WABI 2001, Aarhus, Denmark, August 28-31, 2001, Proceedings. Lecture Notes in Computer Science, 2149 . Springer-Verlag, Berlin / Heidelberg, pp. 52-68. ISBN 0302-9743

Toda, T., Broek, D., Field, J., Michaeli, T., Cameron, S., Nikawa, J., Sass, P., Birchmeier, C., Powers, S., Wigler, M. H. (1987) Exploring the function of RAS oncogenes by studying the yeast Saccharomyces cerevisiae. In: Oncogenes and cancer : proceedings of the 17th International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, 1986. Princess Takamatsu Symposia , 17 . Japan Scientific Societies Press, Tokyo, pp. 253-260. ISBN 4762205176

Wigler, M. H., Powers, S., Kataoka, T., Toda, T., Fasano, O., Matsumoto, K., Uno, I., Ishikawa, T., Broach, J. (1985) Function of Yeast Ras Genes. In: Genetics, cell differentiation, and cancer. Bristol-Myers cancer symposia, 7 (ED.). Academic Press, Orlando, pp. 153-164.

Wigler, M. H., Shimizu, K., Goldfarb, M., Perucho, M., Taparowski, E., Kamata, T., Feramisco, J. (1984) Identification Isolation and Preliminary Characterization of 3 Human Transforming Genes. In: Cell fusion : gene transfer and transformation. Miles international symposium series , 14 (ED.). Raven Press, New York, pp. 101-112.

Wigler, M. H., Fasano, O., Taparowsky, E., Powers, S., Kataoka, T., Birnbaum, D., Shimizu, K., Goldfarb, M. (1984) Structure and Activation of Ras Genes. In: Oncogenes and viral genes. Cancer cells, 2 (ED.). Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 419-424. ISBN 0879691697

Taparowsky, E., Suard, Y., Fasano, O., Shimizu, K., Goldfarb, M., Wigler, M. H. (1983) Activation of the Human H-Ras Gene. In: Recombinant DNA applications to human disease. Banbury report, 14 (ED.). Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 123-134. ISBN 0879692146

Wigler, M. H., Goldfarb, M., Shimizu, K., Perucho, M., Suard, Y., Fasano, O., Taparowsky, E., Fogh, J. (1983) Identification Isolation and Characterization of 3 Distinct Human Transforming Genes. In: Genes and proteins in oncogenesis. P & S biomedical sciences symposia series (ED.). Academic Press, New York, pp. 285-292. ISBN 0127424202

Wigler, M. H., Ford, J. P., Weinstein, I. B. (1975) Glucocorticoid inhibition of the fibrinolytic activity of tumor cells. In: Proteases and Biological Control. Cold Spring Harbor Conferences on Cell Proliferation, 2 . Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 849−856 . ISBN 0097-5230

Monograph

Wigler, M. H. (June 2013) Cold Spring Harbor Laboratory Annual Reports Excerpts: Wigler Laboratory 1979-2011. Project Report. Cold Spring Harbor Laboratory.

Conference or Workshop Item

Simhal, Anish Kumar, Maclachlan, Kylee H, Usmani, Saad Z, Norton, Larry, Deasy, Joseph O, Oh, Jung Hun, Tannenbaum, Allen (November 2023) Network Modeling of Apoptosis-Related Genes Reveal a High-Risk Cluster in Multiple Myeloma. In: UNSPECIFIED.

Moffitt, Andrea B, Alexander, Joan, Stepansky, Asya, Boyle, Erin, Stauder, Danielle, Lopez, Carlos Alberto, Wu, Vernon, Hakim, Nausheen, Wang, Zihua, Kolitz, Jonathan E, Chiorazzi, Nicholas, Chitty, David W, Allen, Steven L, Levy, Dan, Wigler, Michael (November 2023) Personalized Residual Disease Detection in Acute Myeloid Leukemia with a Multiplexed Genomic Fingerprint Predicts Patient Outcomes. In: UNSPECIFIED.

Belkhatir, Z, Berkane, S, Norton, L, Tannenbaum, A (November 2023) Nonlinear Impulsive Control Design for Biologically Grounded NSM Tumor Growth Model Using Exact Linearized Mapping. In: UNSPECIFIED.

Shen, Sherry, Solomon, Verna, Williams, Dominiq, Robson, Mark E, Norton, Larry, Traina, Tiffany A, Iyengar, Neil M (2023) The ARETHA study: A phase 2 randomized control trial of eribulin with evexomostat (SDX7320) or placebo for patients with metastatic triple-negative breast cancer (TNBC) and metabolic dysfunction. In: UNSPECIFIED.

Kaur, Gagandeep, Selenica, Pier, Gazzo, Andrea, Cartagena, Lorraine Colon, Daaboul, Fayez, Dopeso, Higinio, da Silva, Edaise M, Ross, Dara, Zhang, Hong Amy, Wen, Hannah, Chandarlapaty, Sarat, Robson, Mark, Mandelker, Diana, Powell, Simon, Norton, Larry, Brogi, Edi, Reis-Filho, Jorge, Pareja, Fresia (2023) The Histologic and Genomic Features of Breast Cancers Harboring Genetic Alterations in RecQ DNA Helicases. In: 112th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), MAR 11-16, 2023, Mexico.

Zhi, Iris, Lake, Diana E, Ehrich, Fiona, Chen, Yuan, Korc-Grodzicki, Beatriz, Norton, Larry, Robson, Mark E, Singh, Jasmeet Chadha (2023) Older patients with early-stage triple-negative breast cancer: The Memorial Sloan Kettering Cancer Center experience. In: UNSPECIFIED.

Safonov, A, Mehine, M, Ceyhan-Birsoy, O, Brown, D, Bandlamudi, C, Forbes, A, Gazzo, A, Selenica, P, Shen, R, Khurana, E, Norton, L, Solit, D, Chandarlapaty, S, Razavi, P, Robson, M, Weigelt, B, Berger, M, Ladanyi, M, Reis-Filho, JS, Mandelker, D (2023) Pan-cancer assessment of the impact of intronic variants on cancer development and progression. In: UNSPECIFIED.

Abuhadra, Nour, Chen, Yuan, Plitas, George, Razavi, Pedram, Pareja, Fresia, Reis-Filho, Jorge S, Wen, Hannah Yong, Khan, Atif J, Traina, Tiffany A, Downs-Canner, Stephanie, Robson, Mark E, Norton, Larry, Montagna, Giacomo (2023) Prospective evaluation of pathologic response with neoadjuvant chemo-immunotherapy in metaplastic breast cancer. In: UNSPECIFIED.

Bhaloo, Shirin, Gazzo, Andrea, Paula, Arnaud Da Cruz, da Silva, Edaise M, Selenica, Pier, Zhu, Yingjie, Blanco-Heredia, Juan, Pei, Xin, Patel, Juber, Wen, Hannah, Riaz, Nadeem, Powell, Simon, Chandarlapaty, Sarat, Norton, Larry, Brown, David, Weigelt, Britta, Pareja, Fresia, Reis-Filho, Jorge (2023) Whole-genome Sequencing Analysis of Metaplastic Breast Cancers Shows Infrequent Homologous Recombination Deficiency. In: 112th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology (USCAP), MAR 11-16, 2023, Mexico.

McArthur, Heather L, Comen, Elizabeth Anne, Bryce, Yolanda, Solomon, Stephen Barnett, Leal, Jorge Henrique S, Abaya, Christina DiLauro, Martinez, Cristal, Basho, Reva K, McAndrew, Philomena, Larkin, Brigid, Page, David B, Mellinger, Staci L, Fredrich, Nicole, Moxon, Nicole, Reddy, Sangeetha M, Carter, Meredith, Patil, Sujata, Dogan, Basak, Gatti-Mays, Margaret Elena, Norton, Larry (2023) A single-arm phase 2 study of peri-operative immune checkpoint inhibition and cryoablation in women with hormone receptor-negative, HER2-negative, early-stage/resectable breast cancer. In: UNSPECIFIED.

Safonov, Anton Mikhailovich, Bandlamudi, Chaitanya, Selenica, Pier, Marra, Antonio, Ferraro, Emanuela, Mandelker, Diana, Solit, David B, Berger, Michael F, Norton, Larry, Powell, Simon N, Shen, Ronglai, Robson, Mark E, Chandarlapaty, Sarat, Reis-Filho, Jorge S, Razavi, Pedram (2022) Allelic dosage of RB1 drives CDK4/6 inhibitor treatment resistance in metastatic breast cancer. In: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), JUN 03-07, 2022.

Simhal, Anish K, Maclachlan, Kylee H, Elkin, Rena, Zhu, Jiening, Usmani, Saad, Keats, Jonathan J, Norton, Larry, Deasy, Joseph O, Oh, Jung Hun, Tannenbaum, Allen (2022) Geometric Network Analysis Defines Poor-Prognosis Subtypes in Multiple Myeloma. In: 64th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), DEC 10-13, 2022, New Orleans, LA.

Tao, Jacqueline, Setton, Jeremy, Vela, Pablo Sanchez, Safonov, Anton Mikhailovich, Comen, Elizabeth Anne, Braunstein, Lior Zvi, Reis-Filho, Jorge S, Riaz, Nadeem, Powell, Simon N, Levine, Ross L, Norton, Larry, Khan, Atif J, Razavi, Pedram (2022) Impact of clonal hematopoiesis on tumor control following radiation therapy. In: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), JUN 03-07, 2022.

Ren, Zuen, Liang, Huizhi, Dharmaratne, Malindrie, Morales-Gallego, Miriam, Fard, Atefeh Taherian, Mar, Jessica, Suyama, Kimita, Benard, Outhiriaradjou, Prystowsky, Michael B, Norton, Larry, Hazan, Rachel B (2022) Loss of glutathione peroxidase 2 promotes epithelial to mesenchymal transition and breast cancer metastasis. In: American Association for Cancer Research Annual Meeting 2022, 2022 Apr 8-13, Philadelphia, PA.

Khosravi, Pegah, Sutton, Elizabeth J, Jee, Justin, Dalfonso, Timothy, Fong, Christopher J, Rose, Doori, Da Silva, Edaise M, Kohli, Armaan, Ho, David Joon, Ahmed, Mehnaj S, Martinez, Danny, Begum, Anika, Zakszewski, Elizabeth, Aukerman, Andrew, Tazi, Yanis, Pinker-Domenig, Katja, Eskreis-Winkler, Sarah, Khan, Atif J, Brogi, Edi, Morris, Elizabeth, Chandarlapaty, Sarat, Plitas, George, Powell, Simon, Morrow, Monica, Norton, Larry, Gao, Jianjiong, Robson, Mark, Zhang, Hong, Shah, Sohrab, Razavi, Pedram (2022) Prediction of neoadjuvant treatment outcomes with multimodal data integration in breast cancer. In: American Association for Cancer Research Annual Meeting 2022, 2022 Apr 8-13, Philadelphia, PA.

Liang, Huizhi, Benard, Outhiriaradjou, Ren, Zuen, Suyama, Kimita, Norton, Larry, Hazan, Rachel B (2022) TCF7 promotes a mammary cancer-stem-like phenotype leading to metastasis via potentiation of a hybrid epithelial/mesenchymal (E/M) phenotype. In: American Association for Cancer Research Annual Meeting 2022, 2022 Apr 8-13, Philadelphia, PA.

Moffitt, Andrea B, Alexander, Joan, Stepansky, Asya, Famulare, Christopher, Lopez, Carlos A, Hakim, Nausheen, Wu, Vernon, Wang, Zihua, Kolitz, Jonathan E, Chiorazzi, Nicholas, Allen, Steven L, Levine, Ross L, Levy, Dan, Wigler, Michael (2022) Whole Genome Sequencing Comparison of Acute Myeloid Leukemia at Presentation and Remission Predicts Patient Outcome. In: Meeting Abstract.

McArthur, Heather L, Comen, Elizabeth Anne, Bryce, Yolanda, Solomon, Stephen Barnett, Leal, Jorge Henrique S, Abaya, Christina DiLauro, Martinez, Cristal, Basho, Reva K, Park, Dorothy J, McAndrew, Philomena, Larkin, Brigid, Mills, William, Page, David B, Mellinger, Staci L, Fredrich, Nicole, Moxon, Nicole, Reddy, Sangeetha M, Carter, Meredith, Patil, Sujata, Norton, Larry (2022) A single-arm, phase 2 study of perioperative ipilimumab, nivolumab, and cryoablation in women with hormone receptor-negative, HER2-negative, early-stage/resectable breast cancer. In: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), JUN 03-07, 2022.

Norton, Larry (October 2021) IS THE MAXIMUM TOLERATED DOSE (MDT) STILL THE OPTIMAL GOAL FOR CANCER DRUGS? In: UNSPECIFIED.

Ferraro, Emanuela, Razavi, Pedram, Chandarlapaty, Sarat, Modi, Shanu, Wen, Hannah Yong, Brogi, Edi, Norton, Larry, Robson, Mark E, Dang, Chau T (May 2021) Change in HER2 status after neoadjuvant chemotherapy (NAC) with trastuzumab and pertuzumab (HP) in patients with HER2-positive early-stage breast cancer. In: American Society of Clinical Oncology.

Traina, TA, Theodoulou, M, Dugan, U, Feigin, K, Patil, S, Geneus, S, Godfrey, L, Norton, L, Hudis, C (2009) A novel capecitabine dosing schedule combined with bevacizumab is safe and active in patients with metastatic breast cancer: a phase II study. In: UNSPECIFIED.

Perucho, M., Wigler, M. H. (1980) Linkage and Expression of Foreign DNA in Cultured Animal-Cells. In: Cold Spring Harbor Symposia on Quantitative Biology XLV: Movable Genetic Elements, Cold Spring Harbor, NY.

Thesis

Aboukhalil, Robert (March 2016) Elucidating Cancer Evolution using Single-Cell Sequencing and Comparative Genomics. PhD thesis, Cold Spring Harbor Laboratory.

Bekritsky, M. (August 2014) Detecting de novo microsatellite mutations in a population of families with sporadic autism. PhD thesis, Cold Spring Harbor Laboratory.

Thomas, E. E. (April 2004) Exploring Repetitive Sequences in the Human Genome. PhD thesis, Cold Spring Harbor Laboratory.

Patent

Michael Wigler (2014) Use of representations of DNA for genetic analysis. United States Patent 8663917. .

Michael Wigler (2013) Determining a probabilistic diagnosis of autism by analysis of genomic copy number variations. United States Patent 8554488. .

Michael Wigler (2009) Use of representations of DNA for genetic analysis. United States Patent 7531307. .

Michael Wigler (2005) Complex combinatorial chemical libraries encoded with tags. United States Patent 6936477. .

Michael Wigler (2003) Complex combinatorial chemical libraries encoded with tags. United States Patent 6503759. .

Michael Wigler (2003) Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules. United States Patent 6635424. .

Michael Wigler (2003) Methods for identifying modulators of gene expression. United States Patent 6569617. .

Michael Wigler (2002) Cancer detection probes. United States Patent 6350576. .

Michael Wigler (2002) DNA construct for producing proteinaceous materials in eucaryotic cells. United States Patent 6455275. .

Michael Wigler (2002) Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules. United States Patent 6479243. .

Michael Wigler (2001) Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules. United States Patent 6303313. .

Michael Wigler (2001) Representational approach to DNA analysis. United States Patent 6277606. .

Michael Wigler (2000) Cloning by complementation and related processes. United States Patent 6069240. .

Michael Wigler (2000) Cloning by complementation and related processes. United States Patent 6100025. .

Michael Wigler (2000) Cloning of mammalian genes in microbial organisms and methods for pharmacological screening. United States Patent 6080540. .

Michael Wigler (2000) Methods for producing probes capable of distinguishing DNA from related sources. United States Patent 6159713. .

Michael Wigler (1999) Cloning by complementation and related processes. United States Patent 5977305. .

Michael Wigler (1999) Supports and combinatorial chemical libraries thereof encoded by non-sequencable tags. United States Patent 6001579. .

Michael Wigler (1998) Complex combinatorial chemical libraries encoded with tags. United States Patent 5721099. .

Michael Wigler (1998) Method for generating libaries of antibody genes comprising amplification of diverse antibody DNAs and methods for using these libraries for the production of diverse antigen combining molecules. United States Patent 5780225. .

Michael Wigler (1996) Cancer detection probes. United States Patent 5569753. .

Michael Wigler (1996) Cloning by complementation and related processes. United States Patent 5527896. .

Michael Wigler (1996) Complex combinatorial chemical libraries encoded with tags. United States Patent 5565324. .

Michael Wigler (1996) Methods for producing probes capable of distinguishing DNA from related sources. United States Patent 5501964. .

Michael Wigler (1996) Methods for recording the reaction history of a solid support. United States Patent 5968736. .

Michael Wigler (1996) Representational approach to DNA analysis. United States Patent 5876929. .

Michael Wigler (1995) Methods for producing probes capable of distingushing variant genomic sequences. United States Patent 5436142. .

Michael Wigler (June 1994) DNA sequence encoding mas onhcogene, polypeptides encoded therefrom and diagnostic and other methods based therefrom. United States Patent 5320941. .

Michael Wigler (1994) DNA sequence encoding mas onhcogene, polypeptides encoded therefrom and diagnostic and other methods based therefrom. United States Patent 5320941. .

Michael Wigler (1993) Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials. United States Patent 5179017. .

Michael Wigler (September 1989) Bioassay for transforming genes and genes detected thereby. United States Patent 4866166. .

Michael Wigler (1987) Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials. United States Patent 4634665. .

Video

Wigler, M. H. (November 2011) Talk from Mike Wigler at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)

Dataset

Hicks, J. B. (2006) Data file sw.dip.amps.txt for deletions. [Dataset] (Unpublished)