Items where Subject is "gene expression"

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Abeshouse, A., Ahn, J., Akbani, R., Ally, A., Amin, S., Andry, C. D., Annala, M., Aprikian, A., Armenia, J., Arora, A., Auman, J. T., Balasundaram, M., Balu, S., Barbieri, C. E., Bauer, T., Benz, C. C., Bergeron, A., Beroukhim, R., Berrios, M., Bivol, A., Bodenheimer, T., Boice, L., Bootwalla, M. S., Borges Dos Reis, R., Boutros, P. C., Bowen, J., Bowlby, R., Boyd, J., Bradley, R. K., Breggia, A., Brimo, F., Bristow, C. A., Brooks, D., Broom, B. M., Bryce, A. H., Bubley, G., Burks, E., Butterfield, Y. S. N., Button, M., Canes, D., Carlotti, C. G., Carlsen, R., Carmel, M., Carroll, P. R., Carter, S. L., Cartun, R., Carver, B. S., Chan, J. M., Chang, M. T., Chen, Y., Cherniack, A. D., Chevalier, S., Chin, L., Cho, J., Chu, A., Chuah, E., Chudamani, S., Cibulskis, K., Ciriello, G., Clarke, A., Cooperberg, M. R., Corcoran, N. M., Costello, A. J., Cowan, J., Crain, D., Curley, E., David, K., Demchok, J. A., Demichelis, F., Dhalla, N., Dhir, R., Doueik, A., Drake, B., Dvinge, H., Dyakova, N., Felau, I., Ferguson, M. L., Frazer, S., Freedland, S., Fu, Y., Gabriel, S. B., Gao, J., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gerstein, M. B., Getz, G., Godwin, A. K., Gopalan, A., Graefen, M., Graim, K., Gribbin, T., Guin, R., Gupta, M., Hadjipanayis, A., Haider, S., Hamel, L., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Holbrook, A. H., Holt, R. A., Holway, A., Hovens, C. M., Hoyle, A. P., Huang, M., Hutter, C. M., Ittmann, M., Iype, L., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Juhl, H., Kahles, A., Kane, C. J., Kasaian, K., Kerger, M., Khurana, E., Kim, J., Klein, R. J., Kucherlapati, R., Lacombe, L., Ladanyi, M., Lai, P. H., Laird, P. W., Lander, E. S., Latour, M., Lawrence, M. S., Lau, K., Lebien, T., Lee, D., Lee, S., Lehmann, K. V., Leraas, K. M., Leshchiner, I., Leung, R., Libertino, J. A., Lichtenberg, T. M., Lin, P., Linehan, W. M., Ling, S., Lippman, S. M., Liu, J., Liu, W., Lochovsky, L., Loda, M., Logothetis, C., Lolla, L., Longacre, T., Lu, Y., Luo, J., Ma, Y., Mahadeshwar, H. S., Mallery, D., Mariamidze, A., Marra, M. A., Mayo, M., McCall, S., McKercher, G., Meng, S., Mes-Masson, A. M., Merino, M. J., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Shaw, K. R. M., Minner, S., Moinzadeh, A., Moore, R. A., Morris, S., Morrison, C., Mose, L. E., Mungall, A. J., Murray, B. A., Myers, J. B., Naresh, R., Nelson, J., Nelson, M. A., Nelson, P. S., Newton, Y., Noble, M. S., Noushmehr, H., Nykter, M., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Paulauskis, J., Penny, R., Perou, C. M., Piché, A., Pihl, T., Pinto, P. A., Prandi, D., Protopopov, A., Ramirez, N. C., Rao, A., Rathmell, W. K., Rätsch, G., Ren, X., Reuter, V. E., Reynolds, S. M., Rhie, S. K., Rieger-Christ, K., Roach, J., Robertson, A. G., Robinson, B., Rubin, M. A., Saad, F., Sadeghi, S., Saksena, G., Saller, C., Salner, A., Sanchez-Vega, F., Sander, C., Sandusky, G., Sauter, G., Sboner, A., Scardino, P. T., Scarlata, E., Schein, J. E., Schlomm, T., Schmidt, L. S., Schultz, N., Schumacher, S. E., Seidman, J., Neder, L., Seth, S., Sharp, A., Shelton, C., Shelton, T., Shen, H., Shen, R., Sherman, M., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simko, J., Simon, R., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Song, X., Sorcini, A., Sougnez, C., Stepa, S., Stewart, C., Stewart, J., Stuart, J. M., Sullivan, T. B., Sun, C., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Tarvin, K., Taylor, B. S., Teebagy, P., Tenggara, I., Têtu, B., Tewari, A., Thiessen, N., Thompson, T., Thorne, L. B., Tirapelli, D. P., Tomlins, S. A., Trevisan, F. A., Troncoso, P., True, L. D., Tsourlakis, M. C., Tyekucheva, S., Van Allen, E., Van Den Berg, D. J., Veluvolu, U., Verhaak, R., Vocke, C. D., Voet, D., Wan, Y., Wang, Q., Wang, W., Wang, Z., Weinhold, N., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Wise, L., Witte, J., Wu, C. C., Wu, J., Wu, Y., Xu, A. W., Yadav, S. S., Yang, L., Yang, L., Yau, C., Ye, H., Yena, P., Zeng, T., Zenklusen, J. C., Zhang, H., Zhang, J., Zhang, J., Zhang, W., Zhong, Y., Zhu, K., Zmuda, E. (2015) The Molecular Taxonomy of Primary Prostate Cancer. Cell, 163 (4). pp. 1011-1025. ISSN 0092-8674

Agaram, N. P., Laquaglia, M. P., Ustun, B., Guo, T., Wong, G. C., Socci, N. D., Maki, R. G., DeMatteo, R. P., Besmer, P., Antonescu, C. R. (May 2008) Molecular characterization of pediatric gastrointestinal stromal tumors. Clin Cancer Res, 14 (10). pp. 3204-15. ISSN 1078-0432 (Print)1078-0432 (Linking)

Aguirre, A. J., Nowak, J. A., Camarda, N. D., Moffitt, R. A., Ghazani, A. A., Hazar-Rethinam, M., Raghavan, S., Kim, J., Brais, L. K., Ragon, D., Welch, M. W., Reilly, E., McCabe, D., Marini, L., Anderka, K., Helvie, K., Oliver, N., Babic, A., Da Silva, A., Nadres, B., Van Seventer, E. E., Shahzade, H. A., St Pierre, J. P., Burke, K. P., Clancy, T. E., Cleary, J. M., Doyle, L. A., Jajoo, K., McCleary, N. J., Meyerhardt, J. A., Murphy, J. E., Ng, K., Patel, A. K., Perez, K., Rosenthal, M. H., Rubinson, D. A., Ryou, M., Shapiro, G. I., Sicinska, E., Silverman, S. G., Nagy, R. J., Lanman, R. B., Knoerzer, D., Welsch, D. J., Yurgelun, M. B., Fuchs, C. S., Garraway, L. A., Getz, G., Hornick, J. L., Johnson, B. E., Kulke, M. H., Mayer, R. J., Miller, J. W., Shyn, P. B., Tuveson, D. A., Wagle, N., Yeh, J. J., Hahn, W. C., Corcoran, R. B., Carter, S. L., Wolpin, B. M. (June 2018) Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine. Cancer Discov, 8 (9). pp. 1096-1111. ISSN 2159-8274

Ahola, H., Stenlund, A., Moreno-Lopez, J., Pettersson, U. (May 1983) Sequences of bovine papillomavirus type 1 DNA--functional and evolutionary implications. Nucleic Acids Res, 11 (9). pp. 2639-50. ISSN 0305-1048 (Print)0305-1048 (Linking)

Alexander, Katherine A, García-García, María J (January 2019) Imprinted gene expression at the Dlk1-Dio3 cluster is controlled by both maternal and paternal IG-DMRs in a tissue-specific fashion. bioRxiv. (Submitted)

Andersen, L., Ballester, R., Marchuk, D., Saulino, A., Wigler, M. H., Collins, F. (October 1991) Alternative Splicing in the Proposed Catalytic Domain of the Type-1 Neurofibromatosis Gene. American Journal of Human Genetics, 49 (4). p. 21. ISSN 0002-9297

Andersen, L. B., Ballester, R., Marchuk, D. A., Chang, E., Gutmann, D. H., Saulino, A. M., Camonis, J., Wigler, M. H., Collins, F. S. (January 1993) A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity. Molecular and Cellular Biology, 13 (1). pp. 487-495. ISSN 0270-7306

Antonescu, C. R., Viale, A., Sarran, L., Tschernyavsky, S. J., Gonen, M., Segal, N. H., Maki, R. G., Socci, N. D., DeMatteo, R. P., Besmer, P. (May 2004) Gene expression in gastrointestinal stromal tumors is distinguished by KIT genotype and anatomic site. Clin Cancer Res, 10 (10). pp. 3282-90. ISSN 1078-0432 (Print)1078-0432 (Linking)

Asp, M., Giacomello, S., Larsson, L., Wu, C., Furth, D., Qian, X., Wardell, E., Custodio, J., Reimegard, J., Salmen, F., Osterholm, C., Stahl, P. L., Sundstrom, E., Akesson, E., Bergmann, O., Bienko, M., Mansson-Broberg, A., Nilsson, M., Sylven, C., Lundeberg, J. (December 2019) A Spatiotemporal Organ-Wide Gene Expression and Cell Atlas of the Developing Human Heart. Cell, 179 (7). 1647-1660.e19. ISSN 0092-8674

Athma, P., Grotewold, E., Peterson, T. (May 1992) Insertional mutagenesis of the maize P gene by intragenic transposition of Ac. Genetics, 131 (1). pp. 199-209. ISSN 0016-6731 (Print)0016-6731 (Linking)

Aurora, R., Herr, W. (1991) Oct-1 Binds to Diverse Target Sequences through Interactions with Multiple Regions of the Pou-Domain. Journal of Cellular Biochemistry, 47 (Suppl ). p. 170.

Balasooriya, Gayan I, Spector, David L (October 2022) Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage. Nature Communications, 13 (1). p. 5984. ISSN 2041-1723

Ballester, R., Marchuk, D., Boguski, M., Saulino, A., Letcher, R., Wigler, M. H., Collins, F. (November 1990) The NF1 locus encodes a protein functionally related to mammalian GAP and yeast IRA proteins. Cell, 63 (4). pp. 851-9. ISSN 0092-8674

Ballester, R., Wigler, M. H. (1990) Isolation and Characterization of Genes That Regulate Ras Function in the Yeast Saccharomyces-Cerevisiae. Yeast, 6 (SPEC. ). S212.

Ballesteros, M. L., Bolle, C., Lois, L. M., Moore, J. M., Vielle-Calzada, J. P., Grossniklaus, U., Chua, N. H. (October 2001) LAF1, a MYB transcription activator for phytochrome A signaling. Genes & Development, 15 (19). pp. 2613-2625. ISSN 0890-9369

Ballouz, S., Gillis, J. (April 2016) AuPairWise: A Method to Estimate RNA-Seq Replicability through Co-expression. PLoS Comput Biol, 12 (4). e1004868. ISSN 1553-7358 (Electronic)1553-734X (Linking)

Ballouz, S., Pavlidis, P., Gillis, J. (October 2016) Using predictive specificity to determine when gene set analysis is biologically meaningful. Nucleic Acids Res. ISSN 1362-4962 (Electronic)0305-1048 (Linking)

Ballouz, Sara, Mangala, Melissa M, Perry, Matthew D, Heitmann, Stewart, Gillis, Jesse A, Hill, Adam P, Vandenberg, Jamie I (October 2020) Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events. Cardiovascular Research. ISSN 0008-6363

Barr, M. M., Tu, H., Van Aelst, L., Wigler, M. H. (October 1996) Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe. Mol Cell Biol, 16 (10). pp. 5597-603. ISSN 0270-7306 (Print)

Batut, P. J., Dobin, A., Plessy, C., Carninci, P., Gingeras, T. R. (2013) High-fidelity promoter profiling reveals widespread alternative promoter usage and transposon-driven developmental gene expression. Genome Res, 23 (1). pp. 169-180. ISSN 1549-5469 (Electronic)1088-9051 (Linking)

Baulcombe, D., Huttly, A., Martienssen, R. (1987) Hormonal and development control of gene expression in wheat. Biochem Soc Trans, 15 (1). pp. 9-11. ISSN 0300-5127

Belleau, Pascal, Deschênes, Astrid, Chambwe, Nyasha, Tuveson, David A, Krasnitz, Alexander (December 2022) Genetic ancestry inference from cancer-derived molecular data across genomic and transcriptomic platforms. Cancer Research. CAN-22. ISSN 0008-5472

Benoit, Matthias (January 2022) Hot 'n cold: Applying the cis-regulatory code to predict heat and cold stress response in maize. The Plant cell, 34 (1). pp. 497-498. ISSN 1532-298X

Bessho, Y., Nawa, H., Nakanishi, S. (January 1994) Selective up-Regulation of an Nmda Receptor Subunit Messenger-Rna in Cultured Cerebellar Granule Cells by K+-Induced Depolarization and Nmda Treatment. Neuron, 12 (1). pp. 87-95. ISSN 0896-6273

Beyaz, S., Kim, J. H., Pinello, L., Xifaras, M. E., Hu, Y., Huang, J., Kerenyi, M. A., Das, P. P., Barnitz, R. A., Herault, A., Dogum, R., Haining, W. N., Yilmaz, O. H., Passegue, E., Yuan, G. C., Orkin, S. H., Winau, F. (February 2017) The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells. Nat Immunol, 18 (2). pp. 184-195. ISSN 1529-2916 (Electronic)1529-2908 (Linking)

Beyaz, Semir, Mana, Miyeko D, Yilmaz, Ömer H (April 2021) High-fat diet activates a PPAR-δ program to enhance intestinal stem cell function. Cell Stem Cell, 28 (4). pp. 598-599. ISSN 1934-5909

Bhagwat, A. S., Vakoc, C. R. (September 2015) Targeting Transcription Factors in Cancer. Trends Cancer, 1 (1). pp. 53-65. ISSN 2405-8033 (Print)

Birchmeier, C., Birnbaum, D., Waitches, G., Fasano, O., Wigler, M. H. (1986) Characterization of an activated human ros gene. Molecular & Cellular Biology, 6 (9). pp. 3109-3116.

Birchmeier, C., O'Neill, K., Riggs, M., Wigler, M. H. (1990) Characterization of Ros1 cDNA from a Human Glioblastoma Cell Line. Proceedings of the National Academy of Sciences of the United States of America, 87 (12). pp. 4799-4803.

Birchmeier, C., Sharma, S., Wigler, M. H. (December 1987) Expression and rearrangement of the ROS1 gene in human glioblastoma cells. Proc Natl Acad Sci U S A, 84 (24). pp. 9270-4. ISSN 0027-8424

Birchmeier, C., Young, D., Wigler, M. H. (June 1986) Characterization of two new human oncogenes. Cold Spring Harbor Symposia on Quantitative Biology, 51 (2). pp. 993-1000. ISSN 00917451 (ISSN)

Blasco, M. A., Funk, W., Villeponteau, B., Greider, C. W. (September 1995) Functional characterization and developmental regulation of mouse telomerase RNA. Science, 269 (5228). pp. 1267-70. ISSN 0036-8075 (Print)

Boguski, M. S., Murray, A. W., Powers, S. (April 1992) Novel repetitive sequence motifs in the alpha and beta subunits of prenyl-protein transferases and homology of the alpha subunit to the MAD2 gene product of yeast. The New Biologist, 4 (4). pp. 408-11. ISSN 1043-4674 (Print)1043-4674

Bolger, G., Michaeli, T., Martins, T., St John, T., Steiner, B., Rodgers, L., Riggs, M., Wigler, M. H., Ferguson, K. (October 1993) A family of human phosphodiesterases homologous to the dunce learning and memory gene product of Drosophila melanogaster are potential targets for antidepressant drugs. Mol Cell Biol, 13 (10). pp. 6558-71. ISSN 0270-7306 (Print)

Bolger, G. B., Rodgers, L., Riggs, M. (November 1994) Differential CNS expression of alternative mRNA isoforms of the mammalian genes encoding cAMP-specific phosphodiesterases. Gene, 149 (2). pp. 237-44. ISSN 0378-1119 (Print)

Bolwig, G., Chromey, C., Crittenden, J., Dauwalder, B., Dezazzo, J., Han, K. A., Han, P. L., Nighorn, A., Qiu, Y. H., Skoulakis, E., West, R., Wu, K., Davis, R. L. (March 1993) Gene-Expression and Learning in Drosphila. Journal of Cellular Biochemistry, 53 (S17D). p. 246. ISSN 0730-2312

Bortiri, E., Jackson, D. P., Hake, S. (April 2006) Advances in maize genomics: The emergence of positional cloning. Current Opinion in Plant Biology, 9 (2). pp. 164-171. ISSN 13695266

Bott, A. J., Shen, J., Tonelli, C., Zhan, L., Sivaram, N., Jiang, Y. P., Yu, X., Bhatt, V., Chiles, E., Zhong, H., Maimouni, S., Dai, W., Velasquez, S., Pan, J. A., Muthalagu, N., Morton, J., Anthony, T. G., Feng, H., Lamers, W. H., Murphy, D. J., Guo, J. Y., Jin, J., Crawford, H. C., Zhang, L., White, E., Lin, R. Z., Su, X., Tuveson, D. A., Zong, W. X. (October 2019) Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Rep, 29 (5). 1287-1298.e6.

Breschi, A., Djebali, S., Gillis, J., Pervouchine, D. D., Dobin, A., Davis, C. A., Gingeras, T. R., Guigo, R. (2016) Gene-specific patterns of expression variation across organs and species. Genome Biol, 17 (1). p. 151. ISSN 1474-760X (Electronic)1474-7596 (Linking)

Broek, D., Samily, N., Fasano, O., Fujiyama, A., Tamanoi, F., Northup, J., Wigler, M. H. (1985) Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins. Cell, 41 (3). pp. 763-770.

Broek, D., Toda, T., Michaeli, T., Levin, L., Birchmeier, C., Zoller, M., Powers, S., Wigler, M. H. (March 1987) The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell, 48 (5). pp. 789-800.

Brooks, J. E., Gingeras, T. R. (1983) The control of expression of a type-ll restriction modification system from Pseudomonas Aeroginosa. Federation Proceedings, 42 (7). p. 2038. ISSN 0014-9446

Brown, J., Sundaresan, V. (April 1992) Genetic study of the loss and restoration of Mutator transposon activity in maize: evidence against dominant-negative regulator associated with loss of activity. Genetics, 130 (4). pp. 889-98. ISSN 0016-6731 (Print)0016-6731 (Linking)

Byrd, C., Turner, G. C., Varshavsky, A. (1998) The N-end rule pathway controls the import of peptides through degradation of a transcriptional repressor. Embo Journal, 17 (1). pp. 269-277. ISSN 02614189 (ISSN)

Byrne, M. E., Barley, R., Curtis, M., Arroyo, J. M., Dunham, M., Hudson, A., Martienssen, R. A. (December 2000) Asymmetric leaves1 mediates leaf patterning and stem cell function in Arabidopsis. Nature, 408 (6815). pp. 967-971. ISSN 0028-0836

Byrne, M. E., Simorowski, J., Martienssen, R. A. (April 2002) ASYMMETRIC LEAVES1 reveals knox gene redundancy in Arabidopsis. Development, 129 (8). pp. 1957-1965. ISSN 0950-1991

Caligiuri, M., Beach, D. (February 1993) Sct1 functions in partnership with Cdc10 in a transcription complex that activates cell cycle START and inhibits differentiation. Cell, 72 (4). pp. 607-19. ISSN 0092-8674 (Print)

Cameron, S., Levin, L., Zoller, M., Wigler, M. H. (May 1988) cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae. Cell, 53 (4). pp. 555-66. ISSN 0092-8674

Capellini, T. D., Dunn, M. P., Passamaneck, Y. J., Selleri, L., Di Gregorio, A. (November 2008) Conservation of notochord gene expression across chordates: insights from the Leprecan gene family. Genesis, 46 (11). pp. 683-96. ISSN 1526-954x

Carl, S., Daniels, R., Iafrate, A. J., Easterbrook, P., Greenough, T. C., Skowronski, J., Kirchhoff, F. (January 2000) Partial "repair" of defective NEF genes in a long-term nonprogressor with human immunodeficiency virus type 1 infection. Journal of Infectious Diseases, 181 (1). pp. 132-140. ISSN 0022-1899

Carmel, G., Kuret, J. (June 1992) A solid-phase screen for protein kinase substrate selectivity. Anal Biochem, 203 (2). pp. 274-80. ISSN 0003-2697 (Print)0003-2697 (Linking)

Carvalho, F. I., Johns, C., Gillespie, M. E. (May 2012) Gene expression analysis: Teaching Students to do 30,000 Experiments at once with Microarray. Biochemistry and Molecular Biology Education, 40 (3). pp. 181-190. ISSN 1470-8175

Caspari, Ernst W. (1949) On the action of genes in development. Portugaliae acta biologica, Series (R.B. G). pp. 147-160.

Castellano, S., Macchi, F., Scali, M., Huang, Z. J., Bozzi, Y. (September 2006) Cytosolic branched chain aminotransferase (BCATc) mRNA is up-regulated in restricted brain areas of BDNF transgenic mice. Brain Research, 1108 (1). pp. 12-18. ISSN 00068993

Cecchini, Katharine, Biasini, Adriano, Yu, Tianxiong, Säflund, Martin, Mou, Haiwei, Arif, Amena, Eghbali, Atiyeh, Colpan, Cansu, Gainetdinov, Ildar, de Rooij, Dirk G, Weng, Zhiping, Zamore, Phillip, Ozata, Deniz M (November 2022) The transcription factor TCFL5 responds to A MYB to elaborate the male meiotic program in mice. Reproduction. REP-22. ISSN 1470-1626

Chan-Seng-Yue, M., Kim, J. C., Wilson, G. W., Ng, K., Figueroa, E. F., O'Kane, G. M., Connor, A. A., Denroche, R. E., Grant, R. C., McLeod, J., Wilson, J. M., Jang, G. H., Zhang, A., Liang, S. B., Borgida, A., Chadwick, D., Kalimuthu, S., Lungu, I., Bartlett, J. M. S., Krzyzanowski, P. M., Sandhu, V., Tiriac, H., Froeling, F. E. M., Karasinska, J. M., Topham, J. T., Renouf, D. J., Schaeffer, D. F., Jones, S. J. M., Marra, M. A., Laskin, J., Chetty, R., Stein, L. D., Zogopoulos, G., Haibe-Kains, B., Campbell, P. J., Tuveson, D. A., Knox, J. J., Fischer, S. E., Gallinger, S., Notta, F. (January 2020) Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution. Nat Genet. ISSN 1061-4036 (Public Dataset)

Chang, E. C., Barr, M., Wang, Y., Jung, V., Xu, H. P., Wigler, M. H. (October 1994) Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell, 79 (1). pp. 131-41. ISSN 0092-8674 (Print)

Chang, K., Marran, K., Valentine, A., Hannon, G. J. (2013) Creating an miR30-based shRNA vector. Cold Spring Harbor Protocols, 8 (7). pp. 631-635. ISSN 19403402

Chang, K., Marran, K., Valentine, A., Hannon, G. J. (2014) Generation of transgenic drosophila expressing shRNAs in the miR-1 backbone. Cold Spring Harbor Protocols, 2014 (5). pp. 501-509. ISSN 19403402

Chardin, P., Camonis, J. H., Gale, N. W., van Aelst, L., Schlessinger, J., Wigler, M. H., Bar-Sagi, D. (May 1993) Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science, 260 (5112). pp. 1338-1343.

Chattopadhyaya, B., Di Cristo, G., Higashiyama, H., Knott, G. W., Kuhlman, S. J., Welker, E., Huang, Z. J. (October 2004) Experience and activity-dependent maturation of perisomatic GABAergic innervation in primary visual cortex during a postnatal critical period. Journal of Neuroscience, 24 (43). pp. 9598-611. ISSN 0270-6474

Cheadle, L., Tzeng, C. P., Kalish, B. T., Harmin, D. A., Rivera, S., Ling, E., Nagy, M. A., Hrvatin, S., Hu, L., Stroud, H., Burkly, L. C., Chen, C., Greenberg, M. E. (August 2018) Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement. Neuron, 99 (3). 525-539.e10. ISSN 0896-6273 (Print)0896-6273

Chen, Qian, Wang, Saisai, Zhang, Juqing, Xie, Min, Lu, Bin, He, Jie, Zhen, Zhuoran, Li, Jing, Zhu, Jiajun, Li, Rong, Li, Pilong, Wang, Haifeng, Vakoc, Christopher, Roeder, Robert G, Chen, Mo (October 2024) JMJD1C forms condensates to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells. Protein and Cell. pwae059. ISSN 1674-800X (Public Dataset)

Chen, C. D., Helfman, D. M. (February 1999) Donor site competition is involved in the regulation of alternative splicing of the rat beta-tropomyosin pre-mRNA. Rna, 5 (2). pp. 290-301. ISSN 1355-8382 (Print)

Chen, C. D., Kobayashi, R., Helfman, D. M. (March 1999) Binding of hnRNP H to an exonic splicing silencer is involved in the regulation of alternative splicing of the rat beta-tropomyosin gene. Genes and Development, 13 (5). pp. 593-606. ISSN 0890-9369 (Print)

Chen, G. X., Jaradat, S. A., Banerjee, N., Tanaka, T. S., Ko, M. S. H., Zhang, M. Q. (January 2002) Evaluation and comparison of clustering algorithms in analyzing es cell gene expression data. Statistica Sinica, 12 (1). pp. 241-262. ISSN 1017-0405

Chen, J., Guo, T., Zhang, L., Qin, L. X., Singer, S., Maki, R. G., Taguchi, T., Dematteo, R., Besmer, P., Antonescu, C. R. (February 2012) CD133 and CD44 are universally overexpressed in GIST and do not represent cancer stem cell markers. Genes Chromosomes Cancer, 51 (2). pp. 186-95. ISSN 1098-2264 (Electronic)1045-2257 (Linking)

Chen, J. P., Jiao, Y. P., Laza, H., Payton, P., Ware, D., Xin, Z. G. (November 2019) Identification of the First Nuclear Male Sterility Gene (Male-sterile 9) in Sorghum. Plant Genome, 12 (3). Article No 190020. ISSN 1940-3372

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Xu, H. P., Wang, Y., Riggs, M., Rodgers, L., Wigler, M. H. (September 1990) Biological activity of the mammalian RAP genes in yeast. Cell Regulation, 1 (10). pp. 763-769. ISSN 1044-2030

Xu, R. M. (June 2003) A pivotal role of the coiled coil of Sir4. Structure, 11 (6). pp. 608-609. ISSN 0969-2126

Xu, X., Crow, M., Rice, B. R., Li, F., Harris, B., Liu, L., Demesa-Arevalo, E., Lu, Z., Wang, L., Fox, N., Wang, X., Drenkow, J., Luo, A., Char, S. N., Yang, B., Sylvester, A. W., Gingeras, T. R., Schmitz, R. J., Ware, D., Lipka, A. E., Gillis, J., Jackson, D. (December 2020) Single-cell RNA sequencing of developing maize ears facilitates functional analysis and trait candidate gene discovery. Dev Cell, S1534- (20). pp. 31021-31022. ISSN 1534-5807

Xu, Xiaosa, Jackson, David (December 2022) Single-cell analysis opens a goldmine for plant functional studies. Current Opinion in Biotechnology, 79. p. 102858. ISSN 0958-1669

Xue, W., Kitzing, T., Roessler, S., Zuber, J., Krasnitz, A., Schultz, N., Revill, K., Weissmueller, S., Rappaport, A. R., Simon, J., Zhang, J., Luo, W. J., Hicks, J., Zender, L., Wang, X. W., Powers, S., Wigler, M., Lowe, S. W. (May 2012) A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions. Proceedings of the National Academy of Sciences of the United States of America, 109 (21). pp. 8212-8217. ISSN 0027-8424

Xue, W., Krasnitz, A., Lucito, R., Sordella, R., Van Aelst, L., Cordon-Cardo, C., Singer, S., Kuehnel, F., Wigler, M. H., Powers, S., Zender, L., Lowe, S. W. (June 2008) DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes & Development, 22 (11). pp. 1439-44. ISSN 0890-9369

Yaciuk, P., Carter, M. C., Pipas, J. M., Moran, E. (April 1991) Simian virus 40 large-T antigen expresses a biological activity complementary to the p300-associated transforming function of the adenovirus E1A gene products. Mol Cell Biol, 11 (4). pp. 2116-24. ISSN 0270-7306 (Print)0270-7306 (Linking)

Yajnik, V., Paulding, C., Sordella, R., McClatchey, A. I., Saito, M., Wahrer, D. C., Reynolds, P., Bell, D. W., Lake, R., van den Heuvel, S., Settleman, J., Haber, D. A. (March 2003) DOCK4, a GTPase activator, is disrupted during tumorigenesis. Cell, 112 (5). pp. 673-84. ISSN 0092-8674 (Print)

Yan, X., Hu, Z., Feng, Y., Hu, X., Yuan, J., Zhao, S. D., Zhang, Y., Yang, L., Shan, W., He, Q., Fan, L., Kandalaft, L. E., Tanyi, J. L., Li, C., Yuan, C. X., Zhang, D., Yuan, H., Hua, K., Lu, Y., Katsaros, D., Huang, Q., Montone, K., Fan, Y., Coukos, G., Boyd, J., Sood, A. K., Rebbeck, T., Mills, G. B., Dang, C. V., Zhang, L. (2015) Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers. Cancer Cell, 28 (4). pp. 529-540. ISSN 1535-6108

Yang, F., Bui, H. T., Pautler, M., Llaca, V., Johnston, R., Lee, B. H., Kolbe, A., Sakai, H., Jackson, D. (January 2015) A Maize Glutaredoxin Gene, Abphyl2, Regulates Shoot Meristem Size and Phyllotaxy. Plant Cell, 27 (1). pp. 121-131. ISSN 1040-4651

Yang, Yang, Paul, Anirban, Bach, Thao Nguyen, Huang, Z Josh, Zhang, Michael Q (July 2021) Single-cell alternative polyadenylation analysis delineates GABAergic neuron types. BMC Biology, 19 (1). p. 144. ISSN 1741-7007

Yao, Zizhen, Liu, Hanqing, Xie, Fangming, Fischer, Stephan, Adkins, Ricky S, Aldridge, Andrew I, Ament, Seth A, Bartlett, Anna, Behrens, M Margarita, Van den Berge, Koen, Bertagnolli, Darren, de Bézieux, Hector Roux, Biancalani, Tommaso, Booeshaghi, A Sina, Bravo, Héctor Corrada, Casper, Tamara, Colantuoni, Carlo, Crabtree, Jonathan, Creasy, Heather, Crichton, Kirsten, Crow, Megan, Dee, Nick, Dougherty, Elizabeth L, Doyle, Wayne I, Dudoit, Sandrine, Fang, Rongxin, Felix, Victor, Fong, Olivia, Giglio, Michelle, Goldy, Jeff, Hawrylycz, Mike, Herb, Brian R, Hertzano, Ronna, Hou, Xiaomeng, Hu, Qiwen, Kancherla, Jayaram, Kroll, Matthew, Lathia, Kanan, Li, Yang Eric, Lucero, Jacinta D, Luo, Chongyuan, Mahurkar, Anup, McMillen, Delissa, Nadaf, Naeem M, Nery, Joseph R, Nguyen, Thuc Nghi, Niu, Sheng-Yong, Ntranos, Vasilis, Orvis, Joshua, Osteen, Julia K, Pham, Thanh, Pinto-Duarte, Antonio, Poirion, Olivier, Preissl, Sebastian, Purdom, Elizabeth, Rimorin, Christine, Risso, Davide, Rivkin, Angeline C, Smith, Kimberly, Street, Kelly, Sulc, Josef, Svensson, Valentine, Tieu, Michael, Torkelson, Amy, Tung, Herman, Vaishnav, Eeshit Dhaval, Vanderburg, Charles R, van Velthoven, Cindy, Wang, Xinxin, White, Owen R, Huang, Z Josh, Kharchenko, Peter V, Pachter, Lior, Ngai, John, Regev, Aviv, Tasic, Bosiljka, Welch, Joshua D, Gillis, Jesse, Macosko, Evan Z, Ren, Bing, Ecker, Joseph R, Zeng, Hongkui, Mukamel, Eran A (October 2021) A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex. Nature, 598 (7879). pp. 103-110. ISSN 0028-0836

Young, D., O'Neill, K., Broek, D., Wigler, M. H. (June 1991) The adenylyl cyclase-encoding gene from Saccharomyces kluyveri. Gene, 102 (1). pp. 129-32. ISSN 0378-1119

Young, D., O'Neill, K., Jessell, T., Wigler, M. H. (July 1988) Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain. Proc Natl Acad Sci U S A, 85 (14). pp. 5339-42. ISSN 0027-8424

Young, D., Riggs, M., Field, J., Vojtek, A., Broek, D., Wigler, M. H. (October 1989) The adenylyl cyclase gene from Schizosaccharomyces pombe. Proc Natl Acad Sci U S A, 86 (20). pp. 7989-93. ISSN 0027-8424

Young, D., Waitches, G., Birchmeier, C., Fasano, O., Wigler, M. H. (1986) Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains. Cell, 45 (5). pp. 711-720.

Yu, M., Lin, G., Arshadi, N., Kalatskaya, I., Xue, B., Haider, S., Nguyen, F., Boutros, P. C., Elson, A., Muthuswamy, L. B., Tonks, N. K., Muthuswamy, S. K. (October 2012) Expression profiling during mammary epithelial cell 3D morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2 mediated transformation. Mol Cell Biol, 32 (19). pp. 3913-3924. ISSN 1098-5549 (Electronic)0270-7306 (Linking)

Yu, Duonan, dos Santos, Camila O, Zhao, Guowei, Jiang, Jing, Amigo, Julio D, Khandros, Eugene, Dore, Louis C, Yao, Yu, D'Souza, Janine, Zhang, Zhe, Ghaffari, Saghi, Choi, John, Friend, Sherree, Tong, Wei, Orange, Jordan S, Paw, Barry H, Weiss, Mitchell J (August 2010) miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta. Genes and Development, 24 (15). pp. 1620-1633. ISSN 0890-9369

Zebell, S. G. (October 2020) Excising the Mystery of Single-Guide RNA Processing. Plant Physiol, 184 (2). pp. 572-573. ISSN 0032-0889 (Print)0032-0889

Zelko, I., Kobayashi, R., Negishi, M. (May 2000) Repression of phenobarbital-responsive enhancer module in the Cyp2b10 gene by estrogen receptor-related receptor ERR. Faseb Journal, 14 (8). A1433-A1433. ISSN 0892-6638

Zeng, P. Y., Vakoc, C. R., Chen, Z. C., Blobel, G. A., Berger, S. L. (2006) In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation. Biotechniques, 41 (6). pp. 694-698. ISSN 07366205 (ISSN)

Zhang, M. Q. (August 1999) Large-scale gene expression data analysis: a new challenge to computational biologists. Genome Research, 9 (8). pp. 681-8. ISSN 1088-9051 (Print)

Zhang, M. Q. (June 1999) Promoter analysis of co-regulated genes in the yeast genome. Computers & Chemistry, 23 (3-4). pp. 233-50. ISSN 0097-8485 (Print)

Zhang, Y., Mei, P. C., Lou, R., Zhang, M. Q., Wu, G. Y., Qiang, B. Q., Zhang, Z. G., Shen, Y. (October 2002) Gene expression profiling in developing human hippocampus. Journal of Neuroscience Research, 70 (2). pp. 200-208. ISSN 0360-4012

Zhang, R, Atwal, GS, Lim, WK (March 2021) Noise regularization removes correlation artifacts in single-cell RNA-seq data preprocessing. Patterns, 2 (3). p. 100211. ISSN 2666-3899

Zhao, Y., Lin, P., Liufu, Z., Yang, H., Lyu, Y., Shen, X., Wu, C. I., Tang, T. (April 2018) Regulation of large number of weak targets - New insights from twin-microRNAs. Genome Biology and Evolution, 10 (5). pp. 1255-1264. ISSN 17596653 (ISSN)

Zhao, R., Nakamura, T., Fu, Y., Lazar, Z., Spector, D. L. (November 2011) Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation. Nature Cell Biology, 13 (11). 1295-1304 . ISSN 1465-7392

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Zhu, X., Lin, C. R., Prefontaine, G. G., Tollkuhn, J., Rosenfeld, M. G. (June 2005) Genetic control of pituitary development and hypopituitarism. Curr Opin Genet Dev, 15 (3). pp. 332-40. ISSN 0959-437X (Print)0959-437X (Linking)

Zhu, Y., Pak, D., Qin, Y., McCormack, S. G., Kim, M. J., Baumgart, J. P., Velamoor, V., Auberson, Y. P., Osten, P., Van Aelst, L., Sheng, M., Zhu, J. J. (2005) Rap2-JNK removes synaptic AMPA receptors during depotentiation. Neuron, 46 (6). pp. 905-916. ISSN 08966273 (ISSN)

Zhu, Chuanmei, Liu, Lei, Crowell, Olivia, Zhao, Hui, Brutnell, Thomas P, Jackson, David, Kellogg, Elizabeth A (2021) The CLV3 Homolog in Setaria viridis Selectively Controls Inflorescence Meristem Size. Frontiers in Plant Science, 12. p. 636749. ISSN 1664-462X

Zuber, J., Rappaport, A. R., Luo, W., Wang, E., Chen, C., Vaseva, A. V., Shi, J., Weissmueller, S., Fellman, C., Taylor, M. J., Weissenboeck, M., Graeber, T. G., Kogan, S. C., Vakoc, C. R., Lowe, S. W. (August 2011) An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes & Development, 25 (15). pp. 1628-1640. ISSN 0890-9369

van der Horst, E. H., Degenhardt, Y. Y., Strelow, A., Slavin, A., Chinn, L., Orf, J., Rong, M., Li, S., See, L. H., Nguyen, K. Q., Hoey, T., Wesche, H., Powers, S. (November 2005) Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1. Proceedings of the National Academy of Sciences of the United States of America, 102 (44). pp. 15901-6. ISSN 0027-8424

Book Section

Groover, A., Jackson, David (2002) Live-Cell Imaging of GFP in Plants. In: Arabidopsis: A Lab Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp. 262-279. ISBN 0-87969-573-0

Hicks, J. B., Strathern, J. N., Klar, A. J. (1982) Cloning by complementation in yeast: the mating type genes. In: Genetic engineering: principles and methods. Plenum Press, New York, pp. 219-248.

Jackson, D. P. (1992) In-situ hybridisation in plants. In: Molecular Plant Pathology: A Practical Approach. Practical Approach Series, 1 (85). Oxford University Press. ISBN 978-0-19-963102-5

Kessler, M., Gunnery, S., Laspia, M. F., Rice, A. P., Mathews, M. B. (1991) The Role of the Tar Region and Tat Protein in Hiv-Directed Gene Expression. In: Genetic structure and regulation of HIV. Harvard Aids Institute Series on Gene Regulation of Human Retroviruses (ED.). Raven Press, New York, pp. 75-96.

McClintock, Barbara (December 1961) Further studies of the suppressor-mutator system of control of gene action in maize. In: Annual Report of the Director of the Department of Genetics Carnegie Institution of Washington Year Book No. 60, 1960-1961. Carnegie Institution of Washington, Washington, D.C., pp. 469-476.

McClintock, Barbara (1968) Genetic systems regulating gene expression during development. In: Developmental Biology. Supplement 1: The 26th symposium of the society for developmental biology. Developmental Biology. Supplement 1: The 26th Symposium of the Society for Developmental Biology (June, 1967), Control Mechanisms in Developmental Processes . Academic Press, New York, pp. 84-112.

McClintock, Barbara (1980) Modified gene expressions induced by transposable elements. In: Mobilization and reassembly of genetic information: Proceedings of the Miami Winter Symposium, January, 1980. Academic Press, New York, pp. 11-19.

McClintock, Barbara (December 1966) Regulation of pattern of gene expression by controlling elements in maize. In: Carnegie Institution of Washington Year Book 65, 1965-1966. Carnegie Institution of Washington, Washington, D.C., pp. 568-578.

McClintock, Barbara (1971) The contribution of one component of a control system to versatility of gene expression. In: Carnegie Institution of Washington Year Book 70, 1970-1971. Carnegie Institution of Washington, Washington, D.C., pp. 5-17.

Spector, D. L. (2007) Nuclear Organization and Gene Expression. In: From DNA to Proteins: The Multiple Levels of Regulation, The Biomedical & Life Sciences Collection. Henry Stewart Talks Ltd, London.

Spector, David L. (1997) Genes and transcripts in the interphase nucleus. In: Nuclear organization, chromatin structure and gene expression. Oxford University Press, Oxford, pp. 169-184. ISBN 0198549237

Taparowsky, E., Suard, Y., Fasano, O., Shimizu, K., Goldfarb, M., Wigler, M. H. (1983) Activation of the Human H-Ras Gene. In: Recombinant DNA applications to human disease. Banbury report, 14 (ED.). Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 123-134. ISBN 0879692146

Wang, Yalin, Dubnau, Josh, Tully, Tim, Zhong, Yi (2007) Chapter 3 - Genetics in learning and memory. In: Neurobiology of Learning and Memory (Second Edition). Academic Press, Burlington, pp. 103-127. ISBN 978-0-12-372540-0

Wigler, M. H., Fasano, O., Taparowsky, E., Powers, S., Kataoka, T., Birnbaum, D., Shimizu, K., Goldfarb, M. (1984) Structure and Activation of Ras Genes. In: Oncogenes and viral genes. Cancer cells, 2 (ED.). Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 419-424. ISBN 0879691697

Wigler, M. H., Powers, S., Kataoka, T., Toda, T., Fasano, O., Matsumoto, K., Uno, I., Ishikawa, T., Broach, J. (1985) Function of Yeast Ras Genes. In: Genetics, cell differentiation, and cancer. Bristol-Myers cancer symposia, 7 (ED.). Academic Press, Orlando, pp. 153-164.

Conference or Workshop Item

Feigman, Mary J, Moss, Matthew A, Chen, Chen, Cyrill, Samantha L, Ciccone, Michael, Trousdell, Marygrace, Yang, Shih Ting, Frey, Wesley D, Wilkinson, John E, dos Santos, Camila O (June 2020) Pregnancy reprograms the epigenome of mammary epithelial cells and blocks the development of premalignant mammary lesions in response to cMYC-overexpression. In: AACR Special Conference on the Evolving Landscape of Cancer Modeling.

Zhu, J., Zhang, M. Q. (January 2000) Cluster, function and promoter: analysis of yeast expression array. In: Pacific Symposium on Biocomputing.

Book

Thor, A., Anderson, P., Raschid, L., Navlakha, S., Saha, B., Khuller, S., Zhang, X. N. (October 2011) Link prediction for annotation graphs using graph summarization. Lecture Notes in Computer Science, 7031 L (Part 1). Springer, pp. 714-729. ISBN 03029743 (ISSN); 9783642250729 (ISBN)

Wang, D., Pan, E., Fang, G., Kumari, S., He, F., Ware, D., Maslov, S., Gerstein, M. (September 2013) Comparative network analysis of gene co-expression networks reveals the conserved and species-specific functions of cell-wall related genes between arabidopsis and poplar. 2013 4th ACM Conference on Bioinformatics, Computational Biology and Biomedical Informatics, ACM-BCB 2013 . ACM, pp. 689-690. ISBN 9781450324342 (ISBN)

Thesis

Bodnar, M. S. (March 2013) The Dynamics of Pluripotency Genes Upon Differentiation of Mouse Embryonic Stem Cells. PhD thesis, Cold Spring Harbor Laboratory.

Eckersley-Maslin, Melanie A. (January 2014) Characteristics of random monoallelic gene expression during embryonic stem cell differentiation. PhD thesis, Cold Spring Harbor Laboratory.

Finigan, P. (August 2011) The origin of novel phenotypic variation in Arabidopsis allopolyploids. PhD thesis, Cold Spring Harbor Laboratory.

Gutbrod, Michael J. (November 2019) Chromosomal Functions of RNA Interference and Small RNAs in Early Mammalian Development. PhD thesis, Cold Spring Harbor Laboratory.

Muratani, M. (April 2005) Regulation of Gene Expression by the Ubiquitin-Proteasome System. PhD thesis, Cold Spring Harbor Laboratory.

Pautler, Michael (August 2013) Meristem size and determinacy in Maize. PhD thesis, Cold Spring Harbor Laboratory.

Rappaport, A. R. (2011) Dissecting tumor suppressor and tumor maintenance genes in poor prognosis AML. PhD thesis, Cold Spring Harbor Laboratory.

Werner, Jonathan M (December 2023) Transcriptomic approaches for investigating developmental lineage: exploiting the X-chromosome as a marker for lineage specification and quantifying the lineage fidelity of neural organoid systems. PhD thesis, Cold Spring Harbor Laboratory.

Yordanov, Georgi Nenov (July 2019) Myc and Spdef: two transcription factors hijacked by pancreatic cancer. PhD thesis, Cold Spring Harbor.

Video

Gillis, J. (November 2012) Talk from Jessie Gillis at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Hammell, C. M. (November 2012) Talk from Chris Hammell at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Mills, A. A. (November 2011) Talk from Alea Mills at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)

Spector, D. L. (November 2012) Talk from David Spector at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Vakoc, C. R. (November 2012) Talk from Chris Vakoc at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Dataset

Mistry, M., Gillis, J., Pavlidis, P. (2013) Data and design files for 6 public datasets used in "Genome-wide expression profiling of schizophrenia using a large combined cohort" Mistry, M. and Gillis, J. and Pavlidis, P. (2013) Molecular Psychiatry, 18 (2). pp. 215-225. [Dataset]

This list was generated on Sat Dec 21 09:09:33 2024 EST.