Items where Subject is "drugs and therapies"

Group by: Authors | Item Type
Jump to: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | R | S | T | U | V | W | X | Y | Z
Number of items at this level: 301.

A

Aberle, M. R., Burkhart, R. A., Tiriac, H., Olde Damink, S. W. M., Dejong, C. H. C., Tuveson, D. A., van Dam, R. M. (January 2018) Patient-derived organoid models help define personalized management of gastrointestinal cancer. Br J Surg, 105 (2). e48-e60. ISSN 0007-1323

Abramson, Harold Alexander (1957) Verbatim recording and transference studies with lysergic acid diethylamide (LSD-25). The Journal of Nervous and Mental Disease, 125 (3). pp. 444-450.

Abramson, Harold Alexander, Sklarofsky, Bernard, Baron, Myrna O., Fremont-Smith, Nicholas (1957) Production of tolerance to psychosis-producing doses of lysergic acid diethylamide. Science, 126 (3281). p. 1020.

Abuhadra, Nour, Chen, Yuan, Plitas, George, Razavi, Pedram, Pareja, Fresia, Reis-Filho, Jorge S, Wen, Hannah Yong, Khan, Atif J, Traina, Tiffany A, Downs-Canner, Stephanie, Robson, Mark E, Norton, Larry, Montagna, Giacomo (2023) Prospective evaluation of pathologic response with neoadjuvant chemo-immunotherapy in metaplastic breast cancer. In: UNSPECIFIED.

Agaram, N. P., Wong, G. C., Guo, T., Maki, R. G., Singer, S., Dematteo, R. P., Besmer, P., Antonescu, C. R. (October 2008) Novel V600E BRAF mutations in imatinib-naive and imatinib-resistant gastrointestinal stromal tumors. Genes Chromosomes Cancer, 47 (10). pp. 853-9. ISSN 1098-2264 (Electronic)1045-2257 (Linking)

Aguirre, A. J., Nowak, J. A., Camarda, N. D., Moffitt, R. A., Ghazani, A. A., Hazar-Rethinam, M., Raghavan, S., Kim, J., Brais, L. K., Ragon, D., Welch, M. W., Reilly, E., McCabe, D., Marini, L., Anderka, K., Helvie, K., Oliver, N., Babic, A., Da Silva, A., Nadres, B., Van Seventer, E. E., Shahzade, H. A., St Pierre, J. P., Burke, K. P., Clancy, T. E., Cleary, J. M., Doyle, L. A., Jajoo, K., McCleary, N. J., Meyerhardt, J. A., Murphy, J. E., Ng, K., Patel, A. K., Perez, K., Rosenthal, M. H., Rubinson, D. A., Ryou, M., Shapiro, G. I., Sicinska, E., Silverman, S. G., Nagy, R. J., Lanman, R. B., Knoerzer, D., Welsch, D. J., Yurgelun, M. B., Fuchs, C. S., Garraway, L. A., Getz, G., Hornick, J. L., Johnson, B. E., Kulke, M. H., Mayer, R. J., Miller, J. W., Shyn, P. B., Tuveson, D. A., Wagle, N., Yeh, J. J., Hahn, W. C., Corcoran, R. B., Carter, S. L., Wolpin, B. M. (June 2018) Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine. Cancer Discov, 8 (9). pp. 1096-1111. ISSN 2159-8274

Aho, E. R., Wang, J., Gogliotti, R. D., Howard, G. C., Phan, J., Acharya, P., Macdonald, J. D., Cheng, K., Lorey, S. L., Lu, B., Wenzel, S., Foshage, A. M., Alvarado, J., Wang, F., Shaw, J. G., Zhao, B., Weissmiller, A. M., Thomas, L. R., Vakoc, C. R., Hall, M. D., Hiebert, S. W., Liu, Q., Stauffer, S. R., Fesik, S. W., Tansey, W. P. (March 2019) Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell Reports, 26 (11). 2916-2928.e13. ISSN 22111247 (ISSN)

Anderson, S. E., Keohan, M. L., D'Adamo, D. R., Maki, R. G. (2006) A retrospective analysis of vinorelbine chemotherapy for patients with previously treated soft-tissue sarcomas. Sarcoma, 2006. p. 15947. ISSN 1357-714X (Print)1357-714X (Linking)

Antonescu, C. R., Besmer, P., Guo, T., Arkun, K., Hom, G., Koryotowski, B., Leversha, M. A., Jeffrey, P. D., Desantis, D., Singer, S., Brennan, M. F., Maki, R. G., DeMatteo, R. P. (June 2005) Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. Clin Cancer Res, 11 (11). pp. 4182-90. ISSN 1078-0432 (Print)1078-0432 (Linking)

Antonescu, C. R., Yoshida, A., Guo, T., Chang, N. E., Zhang, L., Agaram, N. P., Qin, L. X., Brennan, M. F., Singer, S., Maki, R. G. (September 2009) KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors. Cancer Res, 69 (18). pp. 7175-9. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Arun, G., Diermeier, S. D., Spector, D. L. (February 2018) Therapeutic Targeting of Long Non-Coding RNAs in Cancer. Trends Mol Med, 24 (3). pp. 257-277. ISSN 1471-4914

B

Balagula, Y., Pulitzer, M. P., Maki, R. G., Myskowski, P. L. (September 2011) Pigmentary changes in a patient treated with imatinib. J Drugs Dermatol, 10 (9). pp. 1062-6. ISSN 1545-9616 (Print)1545-9616 (Linking)

Bar-Sagi, D., Lees, J., Sherr, C., Weiss, W. (August 2010) MECHANISMS & MODELS OF CANCER. In: 2010 meeting of MECHANISMS & MODELS OF CANCER, August 17–August 21, 2010, Cold Spring Harbor Laboratory.

Barretina, J., Taylor, B. S., Banerji, S., Ramos, A. H., Lagos-Quintana, M., Decarolis, P. L., Shah, K., Socci, N. D., Weir, B. A., Ho, A., Chiang, D. Y., Reva, B., Mermel, C. H., Getz, G., Antipin, Y., Beroukhim, R., Major, J. E., Hatton, C., Nicoletti, R., Hanna, M., Sharpe, T., Fennell, T. J., Cibulskis, K., Onofrio, R. C., Saito, T., Shukla, N., Lau, C., Nelander, S., Silver, S. J., Sougnez, C., Viale, A., Winckler, W., Maki, R. G., Garraway, L. A., Lash, A., Greulich, H., Root, D. E., Sellers, W. R., Schwartz, G. K., Antonescu, C. R., Lander, E. S., Varmus, H. E., Ladanyi, M., Sander, C., Meyerson, M., Singer, S. (August 2010) Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet, 42 (8). pp. 715-21. ISSN 1546-1718 (Electronic)1061-4036 (Linking)

Bell, D. W., Gore, I., Okimoto, R. A., Godin-Heymann, N., Sordella, R., Mulloy, R., Sharma, S. V., Brannigan, B. W., Mohapatra, G., Settleman, J., Haber, D. A. (December 2005) Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Nature Genetics, 37 (12). pp. 1315-6. ISSN 1061-4036

Bell, D. W., Sordella, R., Kwak, E. L., Godin-Heymann, N., Sharma, S. V., Sgroi, D. C., Sequist, L. V., Lynch, T. J., Settleman, J., Haber, D. A. (2006) Molecular targeted therapy of lung cancer. Tumor Biology, 27 (Suppl). ISSN 1010-4283

Belleau, Pascal, Deschênes, Astrid, Chambwe, Nyasha, Tuveson, David A, Krasnitz, Alexander (December 2022) Genetic ancestry inference from cancer-derived molecular data across genomic and transcriptomic platforms. Cancer Research. CAN-22. ISSN 0008-5472

Bennett, Richard L, Monagle, Darby C, Sobh, Amin, Vakoc, Christopher, Smalley, Keiran S, Harbour, J William, Licht, Jonathan D (July 2021) Abstract 82: Identification of essential proliferation and trametinib resistance mechanisms in GNAQ-mutant uveal melanoma. In: AACR Annual Meeting 2021.

Berman, E., Girotra, M., Cheng, C., Chanel, S., Maki, R., Shelat, M., Strauss, H. W., Fleisher, M., Heller, G., Farooki, A. (July 2013) Effect of long term imatinib on bone in adults with chronic myelogenous leukemia and gastrointestinal stromal tumors. Leuk Res, 37 (7). pp. 790-4. ISSN 1873-5835 (Electronic)0145-2126 (Linking)

Berman, E., Nicolaides, M., Maki, R. G., Fleisher, M., Chanel, S., Scheu, K., Wilson, B. A., Heller, G., Sauter, N. P. (May 2006) Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med, 354 (19). pp. 2006-13. ISSN 1533-4406 (Electronic)0028-4793 (Linking)

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Plenker, Dennis, Tuveson, David A, Rishi, Arvind, Wilkinson, John E, McCombie, W Richard, Kostroff, Karen, Spector, David L (February 2022) Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics. Cancer Research. ISSN 0008-5472

Bhattacharjee, S., Nandi, S. (October 2017) DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway. Cell Commun Signal, 15 (1). p. 41. ISSN 1478-811x

Bhattacharjee, S., Nandi, S. (September 2018) Rare Genetic Diseases with Defects in DNA Repair: Opportunities and Challenges in Orphan Drug Development for Targeted Cancer Therapy. Cancers (Basel), 10 (9). ISSN 2072-6694 (Print)2072-6694

Bhattacharjee, S., Nandi, S. (December 2017) Synthetic lethality in DNA repair network: A novel avenue in targeted cancer therapy and combination therapeutics. IUBMB Life, 69 (12). pp. 929-937. ISSN 1521-6543

Biasci, D., Smoragiewicz, M., Connell, C. M., Wang, Z., Gao, Y., Thaventhiran, J. E. D., Basu, B., Magiera, L., Johnson, T. I., Bax, L., Gopinathan, A., Isherwood, C., Gallagher, F. A., Pawula, M., Hudecova, I., Gale, D., Rosenfeld, N., Barmpounakis, P., Popa, E. C., Brais, R., Godfrey, E., Mir, F., Richards, F. M., Fearon, D. T., Janowitz, T., Jodrell, D. I. (November 2020) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. Proc Natl Acad Sci U S A, 117 (46). pp. 28960-28970. ISSN 0027-8424 (Print)0027-8424

Biffi, Giulia, Tuveson, David A (January 2021) Diversity and Biology of Cancer-Associated Fibroblasts. Physiological Reviews, 101 (1). pp. 147-176. ISSN 0031-9333

Binnewies, M., Roberts, E. W., Kersten, K., Chan, V., Fearon, D. F., Merad, M., Coussens, L. M., Gabrilovich, D. I., Ostrand-Rosenberg, S., Hedrick, C. C., Vonderheide, R. H., Pittet, M. J., Jain, R. K., Zou, W., Howcroft, T. K., Woodhouse, E. C., Weinberg, R. A., Krummel, M. F. (May 2018) Understanding the tumor immune microenvironment (TIME) for effective therapy. Nat Med, 24 (5). pp. 541-550. ISSN 1078-8956

Blanke, C. D., Rankin, C., Demetri, G. D., Ryan, C. W., von Mehren, M., Benjamin, R. S., Raymond, A. K., Bramwell, V. H., Baker, L. H., Maki, R. G., Tanaka, M., Hecht, J. R., Heinrich, M. C., Fletcher, C. D., Crowley, J. J., Borden, E. C. (February 2008) Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033. J Clin Oncol, 26 (4). pp. 626-32. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Bonomi, M. R., Misiukiewicz, K., Posner, M., Maki, R. G. (2012) Squamous cell carcinoma of the oral tongue in two patients previously exposed to long-term pegylated liposomal doxorubicin. Oncologist, 17 (12). pp. 1594-5. ISSN 1549-490X (Electronic)1083-7159 (Linking)

Bose, Shree, Barroso, Margarida, Chheda, Milan G, Clevers, Hans, Elez, Elena, Kaochar, Salma, Kopetz, Scott E, Li, Xiao-Nan, Meric-Bernstam, Funda, Meyer, Clifford A, Mou, Haiwei, Naegle, Kristen M, Pera, Martin F, Perova, Zinaida, Politi, Katerina A, Raphael, Benjamin J, Robson, Paul, Sears, Rosalie C, Tabernero, Josep, Tuveson, David A, Welm, Alana L, Welm, Bryan E, Willey, Christopher D, Salnikow, Konstantin, Chuang, Jeffrey H, Shen, Xiling (October 2022) A path to translation: How 3D patient tumor avatars enable next generation precision oncology. Cancer Cell. ISSN 1535-6108

Bots, M., Verbrugge, I., Martin, B. P., Salmon, J. M., Ghisi, M., Baker, A., Stanley, K., Shortt, J., Ossenkoppele, G. J., Zuber, J., Rappaport, A. R., Atadja, P., Lowe, S. W., Johnstone, R. W. (February 2014) Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood, 123 (9). pp. 1341-52. ISSN 0006-4971

Burkhart, R. A., Baker, L. A., Tiriac, H. (May 2018) Testing Susceptibility of Patient-Derived Organoid Cultures to Therapies: Pharmacotyping. Methods Mol Biol, 1787. pp. 253-261. ISSN 1064-3745

Butrynski, J. E., D'Adamo, D. R., Hornick, J. L., Dal Cin, P., Antonescu, C. R., Jhanwar, S. C., Ladanyi, M., Capelletti, M., Rodig, S. J., Ramaiya, N., Kwak, E. L., Clark, J. W., Wilner, K. D., Christensen, J. G., Janne, P. A., Maki, R. G., Demetri, G. D., Shapiro, G. I. (October 2010) Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor. N Engl J Med, 363 (18). pp. 1727-33. ISSN 1533-4406 (Electronic)0028-4793 (Linking)

C

Cable, Jennifer, Greenbaum, Benjamin, Pe'er, Dana, Bollard, Catherine M, Bruni, Sofia, Griffin, Matthew E, Allison, James P, Wu, Catherine J, Subudhi, Sumit K, Mardis, Elaine R, Brentjens, Renier, Sosman, Jeffry A, Cemerski, Saso, Zavitsanou, Anastasia-Maria, Proia, Theresa, Egeblad, Mikala, Nolan, Garry, Goswami, Sangeeta, Spranger, Stefani, Mackall, Crystal L (November 2020) Frontiers in cancer immunotherapy-a symposium report. Annals of the New York Academy of Sciences. ISSN 0077-8923

Cable, Jennifer, Heard, Edith, Hirose, Tetsuro, Prasanth, Kannanganattu V, Chen, Ling-Ling, Henninger, Jonathan E, Quinodoz, Sofia A, Spector, David L, Diermeier, Sarah D, Porman, Allison M, Kumar, Dhiraj, Feinberg, Mark W, Shen, Xiaohua, Unfried, Juan Pablo, Johnson, Rory, Chen, Chun-Kan, Wilusz, Jeremy E, Lempradl, Adelheid, McGeary, Sean E, Wahba, Lamia, Pyle, Anna Marie, Hargrove, Amanda E, Simon, Matthew D, Marcia, Marco, Przanowska, Róża K, Chang, Howard Y, Jaffrey, Samie R, Contreras, Lydia M, Chen, Qi, Shi, Junchao, Mendell, Joshua T, He, Lin, Song, Erwei, Rinn, John L, Lalwani, Mukesh Kumar, Kalem, Murat Can, Chuong, Edward B, Maquat, Lynne E, Liu, Xuhang (November 2021) Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences. ISSN 0077-8923

Caligiuri, Giuseppina, Tuveson, David A (March 2023) Activated fibroblasts in cancer: Perspectives and challenges. Cancer Cell, 41 (3). pp. 434-449. ISSN 1535-6108

Canter, R. J., Qin, L. X., Downey, R. J., Brennan, M. F., Singer, S., Maki, R. G. (November 2007) Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft-tissue sarcoma of the extremity : a retrospective analysis. Cancer, 110 (9). pp. 2050-60. ISSN 0008-543X (Print)0008-543X (Linking)

Canter, R. J., Qin, L. X., Maki, R. G., Brennan, M. F., Ladanyi, M., Singer, S. (December 2008) A synovial sarcoma-specific preoperative nomogram supports a survival benefit to ifosfamide-based chemotherapy and improves risk stratification for patients. Clin Cancer Res, 14 (24). pp. 8191-7. ISSN 1078-0432 (Print)1078-0432 (Linking)

Cao, Zhendong, Budinich, Krista A, Huang, Hua, Lu, Bin, Zhang, Zhen, Ren, Diqiu, Zhou, Yeqiao, Huang, Yuhan, Pingul, Bianca, Kingsley, Molly C, Lenard, Alexandra K, Qi, Jun, Carroll, Martin P, Blobel, Gerd A, Faryabi, Robert B, Bernt, Kathrin M, Berger, Shelley L, Shi, Junwei (July 2021) Abstract LB205: The IRF8-MEF2D transcription factor circuit regulated by a druggable multiple post-translational modification (PTM) reader ZMYND8 in acute myeloid leukemia. In: AACR Annual Meeting 2021.

Carapua, E. F., Gemenetzidis, E., Feig, C., Tuveson, D., Kocher, H. (July 2015) Developing drug combinations to co-target pancreatic cancer and its supporting stroma. Cancer Research, 75 (Supple). B72. ISSN 0008-5472

Carbini, M., Suarez-Farinas, M., Maki, R. G. (May 2018) A method to summarize toxicity in cancer randomized clinical trials. Clin Cancer Res, 24 (20). pp. 4968-4975. ISSN 1078-0432 (Print)1078-0432

Carbonetti, G., Converso, C., Clement, T., Wang, C., Trotman, L., Ojima, I., Kaczocha, M. (October 2019) Docetaxel/cabazitaxel and fatty acid binding protein 5 inhibitors produce synergistic inhibition of prostate cancer growth. Prostate. ISSN 0270-4137

Cassier, P. A., Gelderblom, H., Stacchiotti, S., Thomas, D., Maki, R. G., Kroep, J. R., van der Graaf, W. T., Italiano, A., Seddon, B., Domont, J., Bompas, E., Wagner, A. J., Blay, J. Y. (March 2012) Efficacy of imatinib mesylate for the treatment of locally advanced and/or metastatic tenosynovial giant cell tumor/pigmented villonodular synovitis. Cancer, 118 (6). pp. 1649-55. ISSN 1097-0142 (Electronic)0008-543X (Linking)

Cesne, A. L., Judson, I., Maki, R., Grosso, F., Schuetze, S., Mehren, M. V., Chawla, S. P., Demetri, G. D., Nieto, A., Tanovic, A., Blay, J. Y. (October 2013) Trabectedin is a feasible treatment for soft tissue sarcoma patients regardless of patient age: a retrospective pooled analysis of five phase II trials. Br J Cancer, 109 (7). pp. 1717-24. ISSN 1532-1827 (Electronic)0007-0920 (Linking)

Chandel, N. S., Tuveson, D. A. (July 2014) The Promise and Perils of Antioxidants for Cancer Patients. New England Journal of Medicine, 371 (2). pp. 177-178. ISSN 0028-4793

Cho, H., Herzka, T., Zheng, W., Qi, J., Wilkinson, J. E., Bradner, J. E., Robinson, B. D., Castillo-Martin, M., Cordon-Cardo, C., Trotman, L. C. (January 2014) RapidCaP, a novel GEM model for analysis and therapy of metastatic prostate cancer, reveals Myc as a driver of Pten-mutant metastasis. Cancer Discovery, 4 (3). pp. 318-33. ISSN 21598274

Chugh, R., Wathen, J. K., Maki, R. G., Benjamin, R. S., Patel, S. R., Meyers, P. A., Priebat, D. A., Reinke, D. K., Thomas, D. G., Keohan, M. L., Samuels, B. L., Baker, L. H. (July 2009) Phase II multicenter trial of imatinib in 10 histologic subtypes of sarcoma using a bayesian hierarchical statistical model. J Clin Oncol, 27 (19). pp. 3148-53. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Chugh, R., Wathen, J. K., Patel, S. R., Maki, R. G., Meyers, P. A., Schuetze, S. M., Priebat, D. A., Thomas, D. G., Jacobson, J. A., Samuels, B. L., Benjamin, R. S., Baker, L. H., Sarcoma Alliance for Research through, Collaboration (October 2010) Efficacy of imatinib in aggressive fibromatosis: Results of a phase II multicenter Sarcoma Alliance for Research through Collaboration (SARC) trial. Clin Cancer Res, 16 (19). pp. 4884-91. ISSN 1078-0432 (Print)1078-0432 (Linking)

Chung, Charlie, Nizam, Aaron, Yueh, Brian, Subhash, Santhilal, Eskiocak, Onur, Frimer, Marina, Goldberg, Gary L, Beyaz, Semir (2023) Autologous patient-derived organoid-immune cell co-culture platform for therapeutic discovery in high-grade endometrial cancer. In: 114th Annual Meeting of the American Association for Cancer Research (AACR), APR 14-19, 2023, Orlando, FL.

Cokol, M., Weinstein, Z. B., Yilancioglu, K., Tasan, M., Doak, A., Cansever, D., Mutlu, B., Li, S., Rodriguez-Esteban, R., Akhmedov, M., Guvenek, A., Cokol, M., Cetiner, S., Giaever, G., Iossifov, I., Nislow, C., Shoichet, B., Roth, F. P. (April 2014) Large-Scale Identification and Analysis of Suppressive Drug Interactions. Chemistry & Biology, 21 (4). pp. 541-551. ISSN 1074-5521

Collins, Sierra M, Alexander, Katherine A, Lundh, Stefan, Dimitri, Alexander J, Zhang, Zhen, Good, Charly R, Fraietta, Joseph A, Berger, Shelley L (July 2023) TOX2 coordinates with TET2 to positively regulate central memory differentiation in human CAR T cells. Science Advances, 9 (29). ISSN 2375-2548

Connell, C. M., Raby, S. E. M., Beh, I., Flint, T. R., Williams, E. H., Fearon, D. T., Jodrell, D. I., Janowitz, T. (January 2018) Cancer Immunotherapy Trials Underutilize Immune Response Monitoring. Oncologist, 23 (1). pp. 116-117. ISSN 1083-7159

Connell, Claire M, Brais, Rebecca, Whitaker, Hayley, Upponi, Sara, Beh, Ian, Risdall, Jane, Corrie, Pippa, Janowitz, Tobias, Jodrell, Duncan I (January 2020) Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report. BMC Cancer, 20 (1). p. 38. ISSN 1471-2407

Cook, N., Basu, B., Smith, D. M., Gopinathan, A., Evans, J., Steward, W. P., Palmer, D., Propper, D., Venugopal, B., Hategan, M., Anthoney, D. A., Hampson, L. V., Nebozhyn, M., Tuveson, D., Farmer-Hall, H., Turner, H., McLeod, R., Halford, S., Jodrell, D. (March 2018) A phase I trial of the gamma-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma. Br J Cancer, 118 (6). pp. 793-801. ISSN 0007-0920

Corless, C. L., Ballman, K. V., Antonescu, C. R., Kolesnikova, V., Maki, R. G., Pisters, P. W., Blackstein, M. E., Blanke, C. D., Demetri, G. D., Heinrich, M. C., von Mehren, M., Patel, S., McCarter, M. D., Owzar, K., DeMatteo, R. P. (May 2014) Pathologic and molecular features correlate with long-term outcome after adjuvant therapy of resected primary GI stromal tumor: the ACOSOG Z9001 trial. J Clin Oncol, 32 (15). pp. 1563-70. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Cormier, J. N., Huang, X., Xing, Y., Thall, P. F., Wang, X., Benjamin, R. S., Pollock, R. E., Antonescu, C. R., Maki, R. G., Brennan, M. F., Pisters, P. W. (November 2004) Cohort analysis of patients with localized, high-risk, extremity soft tissue sarcoma treated at two cancer centers: chemotherapy-associated outcomes. J Clin Oncol, 22 (22). pp. 4567-74. ISSN 0732-183X (Print)0732-183X (Linking)

Costa, Iris Munhoz, Moura, Debora Custodio, Lima, Guilherme Meira, Pessoa, Adalberto, dos Santos, Camila Oresco, de Oliveira, Marcos A, Monteiro, Gisele (October 2021) Engineered asparaginase from Erwinia chrysanthemi enhances asparagine hydrolase activity and diminishes enzyme immunoreactivity - a new promise to treat acute lymphoblastic leukemia. Journal of Chemical Technology and Biotechnology. ISSN 0268-2575

D

D'Adamo, D. R., Anderson, S. E., Albritton, K., Yamada, J., Riedel, E., Scheu, K., Schwartz, G. K., Chen, H., Maki, R. G. (October 2005) Phase II study of doxorubicin and bevacizumab for patients with metastatic soft-tissue sarcomas. J Clin Oncol, 23 (28). pp. 7135-42. ISSN 0732-183X (Print)0732-183X (Linking)

Daher, M., Lacouture, M. E., Rathkopf, D., Maki, R. G., Keohan, M. L., Gansukh, B., Chen, H., Abou-Alfa, G. K. (July 2011) Case series of dermatologic events associated with the insulin-like growth factor receptor 1 inhibitor cixutumumab. J Clin Oncol, 29 (21). e638-40. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Dancsok, A. R., Setsu, N., Gao, D., Blay, J. Y., Thomas, D., Maki, R. G., Nielsen, T. O., Demicco, E. G. (July 2019) Expression of lymphocyte immunoregulatory biomarkers in bone and soft-tissue sarcomas. Mod Pathol, 32 (12). pp. 1662-1785. ISSN 0893-3952

Dantas, Ezequiel, Murthy, Anirudh, Ahmed, Tanvir, Ahmed, Mujmmail, Ramsamooj, Shakti, Hurd, Maurice A, Lam, Tiffany, Malbari, Murtaza, Agrusa, Christopher, Elemento, Olivier, Zhang, Chen, Pappin, Darryl J, McGraw, Timothy E, Stiles, Brendon M, Altorki, Nasser K, Goncalves, Marcus D (October 2023) TIMP1 is an early biomarker for detection and prognosis of lung cancer. Clinical and Translational Medicine, 13 (10). e1391. ISSN 2001-1326 (Public Dataset)

De Sanctis, Francesco, Lamolinara, Alessia, Boschi, Federico, Musiu, Chiara, Caligola, Simone, Trovato, Rosalinda, Fiore, Alessandra, Frusteri, Cristina, Anselmi, Cristina, Poffe, Ornella, Cestari, Tiziana, Canè, Stefania, Sartoris, Silvia, Giugno, Rosalba, Del Rosario, Giulia, Zappacosta, Barbara, Del Pizzo, Francesco, Fassan, Matteo, Dugnani, Erica, Piemonti, Lorenzo, Bottani, Emanuela, Decimo, Ilaria, Paiella, Salvatore, Salvia, Roberto, Lawlor, Rita Teresa, Corbo, Vincenzo, Park, Youngkyu, Tuveson, David A, Bassi, Claudio, Scarpa, Aldo, Iezzi, Manuela, Ugel, Stefano, Bronte, Vincenzo (January 2022) Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer. Journal for ImmunoTherapy of Cancer, 10 (1). e003549-e003549. ISSN 2051-1426

DeMatteo, R. P., Ballman, K. V., Antonescu, C. R., Corless, C., Kolesnikova, V., von Mehren, M., McCarter, M. D., Norton, J., Maki, R. G., Pisters, P. W., Demetri, G. D., Brennan, M. F., Owzar, K., American College of Surgeons Oncology Group Intergroup Adjuvant, Gist Study Team for the Alliance for Clinical Trials in Oncolog (September 2013) Long-term results of adjuvant imatinib mesylate in localized, high-risk, primary gastrointestinal stromal tumor: ACOSOG Z9000 (Alliance) intergroup phase 2 trial. Ann Surg, 258 (3). pp. 422-9. ISSN 1528-1140 (Electronic)0003-4932 (Linking)

DeMatteo, R. P., Maki, R. G., Singer, S., Gonen, M., Brennan, M. F., Antonescu, C. R. (March 2007) Results of tyrosine kinase inhibitor therapy followed by surgical resection for metastatic gastrointestinal stromal tumor. Ann Surg, 245 (3). pp. 347-52. ISSN 0003-4932 (Print)0003-4932 (Linking)

Dematteo, R. P., Ballman, K. V., Antonescu, C. R., Maki, R. G., Pisters, P. W., Demetri, G. D., Blackstein, M. E., Blanke, C. D., von Mehren, M., Brennan, M. F., Patel, S., McCarter, M. D., Polikoff, J. A., Tan, B. R., Owzar, K., American College of Surgeons Oncology Group Intergroup Adjuvant, Gist Study Team (March 2009) Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial. Lancet, 373 (9669). pp. 1097-104. ISSN 1474-547X (Electronic)0140-6736 (Linking)

Demetri, G. D., Heinrich, M. C., Fletcher, J. A., Fletcher, C. D., Van den Abbeele, A. D., Corless, C. L., Antonescu, C. R., George, S., Morgan, J. A., Chen, M. H., Bello, C. L., Huang, X., Cohen, D. P., Baum, C. M., Maki, R. G. (September 2009) Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure. Clin Cancer Res, 15 (18). pp. 5902-9. ISSN 1078-0432 (Print)1078-0432 (Linking)

Demetri, G. D., Le Cesne, A., Chawla, S. P., Brodowicz, T., Maki, R. G., Bach, B. A., Smethurst, D. P., Bray, S., Hei, Y. J., Blay, J. Y. (March 2012) First-line treatment of metastatic or locally advanced unresectable soft tissue sarcomas with conatumumab in combination with doxorubicin or doxorubicin alone: a phase I/II open-label and double-blind study. Eur J Cancer, 48 (4). pp. 547-63. ISSN 1879-0852 (Electronic)0959-8049 (Linking)

Demetri, G. D., Reichardt, P., Kang, Y. K., Blay, J. Y., Rutkowski, P., Gelderblom, H., Hohenberger, P., Leahy, M., von Mehren, M., Joensuu, H., Badalamenti, G., Blackstein, M., Le Cesne, A., Schoffski, P., Maki, R. G., Bauer, S., Nguyen, B. B., Xu, J., Nishida, T., Chung, J., Kappeler, C., Kuss, I., Laurent, D., Casali, P. G., investigators, Grid study (January 2013) Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial. Lancet, 381 (9863). pp. 295-302. ISSN 1474-547X (Electronic)0140-6736 (Linking)

Demyan, Lyudmyla, Standring, Oliver, Chung, Taemoon, Gazzara, Emma, Lyons, Scott, Park, Youngkyu, King, Daniel, Jonas, Oliver, Tuveson, David, Weiss, Matthew (2023) Feasibility of Implantable Microdosing Devices to Perform in vivo Pharmacotyping in Pancreatic Cancer. In: Annual International Conference of the Society-of-Surgical-Oncology (SSO) on Surgical Cancer Care, MAR 22-25, 2023, Boston, MA.

Dickson, M. A., D'Adamo, D. R., Keohan, M. L., D'Angelo, S. P., Carvajal, R. D., Gounder, M. M., Maki, R. G., Qin, L. X., Lefkowitz, R. A., McKennon, O. R., Hirst, C. M., Schwartz, G. K., Tap, W. D. (2015) Phase II Trial of Gemcitabine and Docetaxel with Bevacizumab in Soft Tissue Sarcoma. Sarcoma, 2015. p. 532478. ISSN 1357-714X (Print)1357-714X (Linking)

Dickson, M. A., Okuno, S. H., Keohan, M. L., Maki, R. G., D'Adamo, D. R., Akhurst, T. J., Antonescu, C. R., Schwartz, G. K. (January 2013) Phase II study of the HSP90-inhibitor BIIB021 in gastrointestinal stromal tumors. Ann Oncol, 24 (1). pp. 252-7. ISSN 1569-8041 (Electronic)0923-7534 (Linking)

Dodgson, S. E., Santaguida, S., Kim, S., Sheltzer, J., Amon, A. (November 2016) The pleiotropic deubiquitinase Ubp3 confers aneuploidy tolerance. Genes Dev. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Driehuis, E., Kolders, S., Spelier, S., Lohmussaar, K., Willems, S. M., Devriese, L. A., de Bree, R., de Ruiter, E. J., Korving, J., Begthel, H., Van Es, J. H., Geurts, V., He, G. W., van Jaarsveld, R. H., Oka, R., Muraro, M. J., Vivie, J., Zandvliet, Mmjm, Hendrickx, A. P. A., Iakobachvili, N., Sridevi, P., Kranenburg, O., van Boxtel, R., Kops, Gjpl, Tuveson, D. A., Peters, P. J., van Oudenaarden, A., Clevers, H. (May 2019) Oral mucosal organoids as a potential platform for personalized cancer therapy. Cancer Discov, 9 (7). pp. 852-871. ISSN 2159-8274

Dycaico, M. J., Grant, S. G. N., Felts, K., Nichols, W. S., Geller, S. A., Hager, J. H., Pollard, A. J., Kohler, S. W., Short, H. P., Jirik, F. R., Hanahan, D., Sorge, J. A. (December 1988) Neonatal Hepatitis Induced by Alpha-1-Antitrypsin - a Transgenic Mouse Model. Science, 242 (4884). pp. 1409-1412. ISSN 0036-8075

de Camargo, V. P., Keohan, M. L., D'Adamo, D. R., Antonescu, C. R., Brennan, M. F., Singer, S., Ahn, L. S., Maki, R. G. (May 2010) Clinical outcomes of systemic therapy for patients with deep fibromatosis (desmoid tumor). Cancer, 116 (9). pp. 2258-65. ISSN 0008-543X (Print)0008-543X (Linking)

E

Early Breast Cancer Trialists' Collaborative Group (EBCTCG) (February 2022) Aromatase inhibitors versus tamoxifen in premenopausal women with oestrogen receptor-positive early-stage breast cancer treated with ovarian suppression: a patient-level meta-analysis of 7030 women from four randomised trials. The Lancet Oncology. ISSN 1470-2045

Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Ele, Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) (April 2023) Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials. The Lancet, 401 (10384). pp. 1277-1292. ISSN 0140-6736

Egeblad, M., Nakasone, E., Askautrud, H., Wysocki, R., Fein, M., Kees, T., Park, J., Park, J. H. (November 2014) Understanding drug responses and resistance mechanisms using imaging in live mice. Molecular Cancer Research, 12 (Supple). ISSN 1541-7786

Eilber, F. C., Brennan, M. F., Eilber, F. R., Eckardt, J. J., Grobmyer, S. R., Riedel, E., Forscher, C., Maki, R. G., Singer, S. (July 2007) Chemotherapy is associated with improved survival in adult patients with primary extremity synovial sarcoma. Ann Surg, 246 (1). pp. 105-13. ISSN 0003-4932 (Print)0003-4932 (Linking)

Eilber, F. C., Eilber, F. R., Eckardt, J., Rosen, G., Riedel, E., Maki, R. G., Brennan, M. F., Singer, S. (October 2004) The impact of chemotherapy on the survival of patients with high-grade primary extremity liposarcoma. Ann Surg, 240 (4). 686-95; discussion 695. ISSN 0003-4932 (Print)0003-4932 (Linking)

Encinas, J. M., Manganas, L., Enikolopov, G. N. (May 2005) Nitric oxide and multiple sclerosis. Curr Neurol Neurosci Rep, 5 (3). pp. 232-8. ISSN 1528-4042 (Print)

F

Fearon, D. (June 2016) Combination immunotherapy for cancer. J Exp Med, 213 (7). p. 1115. ISSN 1540-9538 (Electronic)0022-1007 (Linking)

Fearon, Douglas, Wang, Zhikai (September 2020) Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy. In: Proceedings of the AACR Virtual Special Conference on Pancreatic Cancer; 2020.

Fernandez, Y., Verhaegen, M., Miller, T. P., Rush, J. L., Steiner, P., Opipari, A. W., Lowe, S. W., Soengas, M. S. (July 2005) Differential regulation of noxa in normal Melanocytes and melanoma cells by proteasome inhibition: Therapeutic implications. Cancer Research, 65 (14). pp. 6294-6304. ISSN 0008-5472

Ferrer, Miriam, Janowitz, Tobias (June 2022) Training the host organism to enhance anti-cancer immunity. Cancer Cell. S1535-6108(22)00267. ISSN 1535-6108

Fields, R. C., Hameed, M., Qin, L. X., Moraco, N., Jia, X., Maki, R. G., Singer, S., Brennan, M. F. (February 2011) Dermatofibrosarcoma protuberans (DFSP): predictors of recurrence and the use of systemic therapy. Ann Surg Oncol, 18 (2). pp. 328-36. ISSN 1534-4681 (Electronic)1068-9265 (Linking)

Firoozan, S, Satpathy, S, Shakiba, M, King, DA (September 2024) Recent advances in immunotherapy for pancreatic cancer: a narrative review. Digestive Medicine Research, 7. p. 15. ISSN 2617-1627

Fisher, Matthew L, Balinth, Seamus, Hwangbo, Yon, Wu, Caizhi, Ballon, Carlos, Wilkinson, John E, Goldberg, Gary L, Mills, Alea A (October 2021) BRD4 REGULATES TRANSCRIPTION FACTOR ∆Np63αTO DRIVE A CANCER STEM CELL PHENOTYPE IN SQUAMOUS CELL CARCINOMAS. Cancer Research. canres.0707.2021-canres.0707.2021. ISSN 0008-5472

Fiskus, Warren, Mill, Christopher P, Nabet, Behnam, Perera, Dimuthu, Birdwell, Christine, Manshouri, Taghi, Lara, Bernardo, Kadia, Tapan M, DiNardo, Courtney, Takahashi, Koichi, Daver, Naval, Bose, Prithviraj, Masarova, Lucia, Pemmaraju, Naveen, Kornblau, Steven, Borthakur, Gautam, Montalban-Bravo, Guillermo, Manero, Guillermo Garcia, Sharma, Sunil, Stubbs, Matthew, Su, Xiaoping, Green, Michael R, Coarfa, Cristian, Verstovsek, Srdan, Khoury, Joseph D, Vakoc, Christopher R, Bhalla, Kapil N (May 2021) Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells. Blood Cancer Journal, 11 (5). p. 98. ISSN 2044-5385

Flint, T. R., Janowitz, T., Connell, C. M., Roberts, E. W., Denton, A. E., Coll, A. P., Jodrell, D. I., Fearon, D. T. (November 2016) Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity. Cell Metab, 24 (5). pp. 672-684. ISSN 1932-7420 (Electronic)1550-4131 (Linking)

Flint, T. R., Jones, J. O., Ferrer, M., Colucci, F., Janowitz, T. (March 2018) A comparative analysis of immune privilege in pregnancy and cancer in the context of checkpoint blockade immunotherapy. Semin Oncol. ISSN 0093-7754

Fraietta, Joseph A, Nobles, Christopher L, Sammons, Morgan A, Lundh, Stefan, Carty, Shannon A, Reich, Tyler J, Cogdill, Alexandria P, Morrissette, Jennifer JD, DeNizio, Jamie E, Reddy, Shantan, Hwang, Young, Gohil, Mercy, Kulikovskaya, Irina, Nazimuddin, Farzana, Gupta, Minnal, Chen, Fang, Everett, John K, Alexander, Katherine A, Lin-Shiao, Enrique, Gee, Marvin H, Liu, Xiaojun, Young, Regina M, Ambrose, David, Wang, Yan, Xu, Jun, Jordan, Martha S, Marcucci, Katherine T, Levine, Bruce L, Garcia, K Christopher, Zhao, Yangbing, Kalos, Michael, Porter, David L, Kohli, Rahul M, Lacey, Simon F, Berger, Shelley L, Bushman, Frederic D, June, Carl H, Melenhorst, J Joseph (June 2018) Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells. Nature, 558 (7709). pp. 307-312. ISSN 0028-0836

Freedberg, D.E., Conigliaro, J., Wang, T.C., Tracey, K.J., Callahan, M.V., Abrams, J.A., On behalf of the Famotidine Research Group, Famotidine Research Group, Sobieszczyk, M.E., Markowitz, D.D., Gupta, A., O'Donnell, M.R., Li, J., Tuveson, D.A., Jin, Z., Turner, W.C., Landry, D.W. (May 2020) Famotidine Use Is Associated With Improved Clinical Outcomes in Hospitalized COVID-19 Patients: A Propensity Score Matched Retrospective Cohort Study. Gastroenterology. ISSN 0016-5085

Frese, K. K., Neesse, A., Cook, N., Bapiro, T. E., Lolkema, M. P., Jodrell, D. I., Tuveson, D. A. (March 2012) nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer. Cancer Discov, 2 (3). pp. 260-9. ISSN 2159-8290 (Electronic)2159-8274 (Linking)

Frezza, A. M., Assi, T., Lo Vullo, S., Ben-Ami, E., Dufresne, A., Yonemori, K., Noguchi, E., Siontis, B., Ferraro, R., Teterycz, P., Duffaud, F., Ravi, V., Vincenzi, B., Gelderblom, H., Pantaleo, M. A., Baldi, G. G., Desar, I., Fedenko, A., Maki, R. G., Jones, R. L., Benjamin, R. S., Blay, J. Y., Kawai, A., Gounder, M., Gronchi, A., Le Cesne, A., Mir, O., Czarnecka, A. M., Schuetze, S., Wagner, A. J., Adam, J., Barisella, M., Sbaraglia, M., Hornick, J. L., Meurgey, A., Mariani, L., Casali, P. G., Thornton, K., Stacchiotti, S. (September 2019) Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network. Cancer. ISSN 0008-543x

Fujii, T, Rehman, H, Chung, SY, Shen, J, Newman, J, Wu, V, Hines, A, Azimi-Nekoo, E, Fayyaz, F, Lee, M, Raptis, G, Egeblad, M, Zhu, X (July 2021) Treatment with granulocyte-colony stimulating factor (G-CSF) is not associated with increased risk of brain metastasis in patients with de novo stage IV breast cancer. Journal of Cancer, 12 (18). pp. 5687-5692. ISSN 1837-9664

Fury, M. G., Antonescu, C. R., Van Zee, K. J., Brennan, M. F., Maki, R. G. (May 2005) A 14-year retrospective review of angiosarcoma: clinical characteristics, prognostic factors, and treatment outcomes with surgery and chemotherapy. Cancer J, 11 (3). pp. 241-7. ISSN 1528-9117 (Print)1528-9117 (Linking)

G

Galluzzi, L., Vacchelli, E., Bravo-San Pedro, J., Buque, A., Senovilla, L., Baracco, E. E., Bloy, N., Castoldi, F., Abastado, J., Agostinis, P., Apte, R. N., Aranda, F., Ayyoub, M., Beckhove, P., Blay, J., Bracci, L., Caignard, A., Castelli, C., Cavallo, F., Celis, E., Cerundolo, V., Clayton, A., Colombo, M. P., Coussens, L., Dhodapkar, M. V., Eggermont, A. M., Fearon, D. T., Fridman, W. H., Fucikova, J., Gabrilovich, D. I., Galon, J., Garg, A., Ghiringhelli, F., Giaccone, G., Gilboa, E., Gnjatic, S., Hoos, A., Hosmalin, A., Jager, D., Kalinski, P., Karre, K., Kepp, O., Kiessling, R., Kirkwood, J. M., Klein, E., Knuth, A., Lewis, C. E., Liblau, R., Lotze, M. T., Lugli, E., Mach, J., Mattei, F., Mavilio, D., Melero, I., Melief, C. J., Mittendorf, E. A., Moretta, L., Odunsi, A., Okada, H., Palucka, A. K., Peter, M. E., Pienta, K. J., Porgador, A., Prendergast, G. C., Rabinovich, G. A., Restifo, N. P., Rizvi, N., Sautes-Fridman, C., Schreiber, H., Seliger, B., Shiku, H., Silva-Santos, B., Smyth, M. J., Speiser, D. E., Spisek, R., Srivastava, P. K., Talmadge, J. E., Tartour, E., Van Der Burg, S. H., Van Den Eynde, B. J., Vile, R., Wagner, H., Weber, J. S., Whiteside, T. L., Wolchok, J. D., Zitvogel, L., Zou, W., Kroemer, G. (December 2014) Classification of current anticancer immunotherapies. Oncotarget, 5 (24). ISSN 1949-2553

Gandy, S., Man-Yee Lee, V., Rothstein, J. (December 2010) NEURODEGENERATIVE DISEASES: BIOLOGY & THERAPEUTICS. In: 2010 meeting of Neurodegenerative diseases, December 1–December 4, 2010, Cold Spring Larbor Laboratory.

Garcia-Carbonero, R., Supko, J. G., Maki, R. G., Manola, J., Ryan, D. P., Harmon, D., Puchalski, T. A., Goss, G., Seiden, M. V., Waxman, A., Quigley, M. T., Lopez, T., Sancho, M. A., Jimeno, J., Guzman, C., Demetri, G. D. (August 2005) Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study. J Clin Oncol, 23 (24). pp. 5484-92. ISSN 0732-183X (Print)0732-183X (Linking)

Garcia-Carbonero, R., Supko, J. G., Manola, J., Seiden, M. V., Harmon, D., Ryan, D. P., Quigley, M. T., Merriam, P., Canniff, J., Goss, G., Matulonis, U., Maki, R. G., Lopez, T., Puchalski, T. A., Sancho, M. A., Gomez, J., Guzman, C., Jimeno, J., Demetri, G. D. (April 2004) Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J Clin Oncol, 22 (8). pp. 1480-90. ISSN 0732-183X (Print)0732-183X (Linking)

Ge, Eva J, Bush, Ashley I, Casini, Angela, Cobine, Paul A, Cross, Justin R, DeNicola, Gina M, Dou, Q Ping, Franz, Katherine J, Gohil, Vishal M, Gupta, Sanjeev, Kaler, Stephen G, Lutsenko, Svetlana, Mittal, Vivek, Petris, Michael J, Polishchuk, Roman, Ralle, Martina, Schilsky, Michael L, Tonks, Nicholas K, Vahdat, Linda T, Van Aelst, Linda, Xi, Dan, Yuan, Peng, Brady, Donita C, Chang, Christopher J (November 2021) Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews Cancer. ISSN 1474-175X

George, S., Merriam, P., Maki, R. G., Van den Abbeele, A. D., Yap, J. T., Akhurst, T., Harmon, D. C., Bhuchar, G., O'Mara, M. M., D'Adamo, D. R., Morgan, J., Schwartz, G. K., Wagner, A. J., Butrynski, J. E., Demetri, G. D., Keohan, M. L. (July 2009) Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas. J Clin Oncol, 27 (19). pp. 3154-60. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Gholami, Sepideh, Colby, Sarah, Horowitz, David P, Guthrie, Katherine A, Ben-Josef, Edgar, El-Khoueiry, Anthony B, Blanke, Charles D, Philip, Philip A, Kachnic, Lisa A, Ahmad, Syed A, Rocha, Flavio G (March 2023) Adjuvant Chemoradiation in Patients with Lymph Node-Positive Biliary Tract Cancers: Secondary Analysis of a Single-Arm Clinical Trial (SWOG 0809). Annals of Surgical Oncology, 30 (3). pp. 1354-1363. ISSN 1068-9265

Gholami, Sepideh, Stewart, Susan, Kemeny, Nancy, Gönen, Mithat, Groot Koerkamp, Bas, Cercek, Andrea, Kingham, Peter, Balachandran, Vinod, Allen, Peter, DeMatteo, Ronald, Wei, Alice, Connell, Louise, Drebin, Jeffrey, Jarnagin, William, D'Angelica, Michael (July 2021) Impact of Primary Tumor Laterality on Adjuvant Hepatic Artery Infusion Pump Chemotherapy in Resected Colon Cancer Liver Metastases: Analysis of 487 Patients. Annals of Surgical Oncology, 28 (7). pp. 3685-3694. ISSN 1068-9265

Ghosh, D., Nandi, S., Bhattacharjee, S. (October 2018) Combination therapy to checkmate Glioblastoma: clinical challenges and advances. Clin Transl Med, 7 (1). p. 33. ISSN 2001-1326 (Print)

Ghosh, D., Venkataramani, P., Nandi, S., Bhattacharjee, S. (January 2019) CRISPR-Cas9 a boon or bane: the bumpy road ahead to cancer therapeutics. Cancer Cell Int, 19. p. 12. ISSN 1475-2867 (Print)1475-2867

Gold, J. S., van der Zwan, S. M., Gonen, M., Maki, R. G., Singer, S., Brennan, M. F., Antonescu, C. R., De Matteo, R. P. (January 2007) Outcome of metastatic GIST in the era before tyrosine kinase inhibitors. Ann Surg Oncol, 14 (1). pp. 134-42. ISSN 1068-9265 (Print)1068-9265 (Linking)

Good, Charly R, Aznar, M Angela, Kuramitsu, Shunichiro, Samareh, Parisa, Agarwal, Sangya, Donahue, Greg, Ishiyama, Kenichi, Wellhausen, Nils, Rennels, Austin K, Ma, Yujie, Tian, Lifeng, Guedan, Sonia, Alexander, Katherine A, Zhang, Zhen, Rommel, Philipp C, Singh, Nathan, Glastad, Karl M, Richardson, Max W, Watanabe, Keisuke, Tanyi, Janos L, O’Hara, Mark H, Ruella, Marco, Lacey, Simon F, Moon, Edmund K, Schuster, Stephen J, Albelda, Steven M, Lanier, Lewis L, Young, Regina M, Berger, Shelley L, June, Carl H (December 2021) An NK-like CAR T cell transition in CAR T cell dysfunction. Cell, 184 (25). 6081-6100.e26. ISSN 0092-8674

Gordon, J. K., Magid, S. K., Maki, R. G., Fleisher, M., Berman, E. (June 2010) Elevations of creatine kinase in patients treated with imatinib mesylate (Gleevec). Leuk Res, 34 (6). pp. 827-9. ISSN 1873-5835 (Electronic)0145-2126 (Linking)

Gounder, M. M., Lefkowitz, R. A., Keohan, M. L., D'Adamo, D. R., Hameed, M., Antonescu, C. R., Singer, S., Stout, K., Ahn, L., Maki, R. G. (June 2011) Activity of Sorafenib against desmoid tumor/deep fibromatosis. Clin Cancer Res, 17 (12). pp. 4082-90. ISSN 1078-0432 (Print)1078-0432 (Linking)

Grobmyer, S. R., Maki, R. G., Demetri, G. D., Mazumdar, M., Riedel, E., Brennan, M. F., Singer, S. (November 2004) Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma. Ann Oncol, 15 (11). pp. 1667-72. ISSN 0923-7534 (Print)0923-7534 (Linking)

Gronchi, A., Maki, R. G., Jones, R. L. (January 2017) Treatment of soft tissue sarcoma: a focus on earlier stages. Future Oncol, 13 (1s). pp. 13-21. ISSN 1744-8301 (Electronic)1479-6694 (Linking)

Guo, T., Agaram, N. P., Wong, G. C., Hom, G., D'Adamo, D., Maki, R. G., Schwartz, G. K., Veach, D., Clarkson, B. D., Singer, S., DeMatteo, R. P., Besmer, P., Antonescu, C. R. (August 2007) Sorafenib inhibits the imatinib-resistant KITT670I gatekeeper mutation in gastrointestinal stromal tumor. Clin Cancer Res, 13 (16). pp. 4874-81. ISSN 1078-0432 (Print)1078-0432 (Linking)

H

Haber, D. A., Bell, D. W., Sordella, R., Kwak, E. L., Godin-Heymann, N., Sharma, S. V., Lynch, T. J., Settleman, J. (2005) Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors. Cold Spring Harbor Symposia on Quantitative Biology, 70. pp. 419-26. ISSN 0091-7451

Harris, L. N., Parker, J., Broadwater, G., Schulz, V., Halligan, K., Geyda, K., Seidman, A., Berry, D., Winer, E., Hudis, C., Krasnitz, A., Hicks, J., Tuck, D. P., Perou, C. (December 2009) Genome-Wide Profiling of Archived Material from CALGB 9840 and 9342 for Paclitaxel (P) and Trastuzumab (T) Response Biomarkers Using Gene Expression and Copy Number Analysis. Cancer Research, 69 (24 (S3). 716S-717S. ISSN 0008-5472

Hastings, Michelle L, Krainer, Adrian R (April 2023) RNA therapeutics. RNA, 29 (4). pp. 393-395. ISSN 1355-8382

He, X. Y., Ng, D., Van Aelst, L., Egeblad, M. (November 2019) Stressing Out about Cancer Immunotherapy. Cancer Cell, 36 (5). pp. 468-470. ISSN 15356108 (ISSN)

Heidegger, Simon, Stritzke, Florian, Dahl, Sarah, Daßler-Plenker, Juliane, Joachim, Laura, Buschmann, Dominik, Fan, Kaiji, Sauer, Carolin M, Ludwig, Nils, Winter, Christof, Enssle, Stefan, Li, Suqi, Perl, Markus, Görgens, André, Haas, Tobias, Orberg, Erik Thiele, Göttert, Sascha, Wölfel, Catherine, Engleitner, Thomas, Cortés-Ciriano, Isidro, Rad, Roland, Herr, Wolfgang, Giebel, Bernd, Ruland, Jürgen, Bassermann, Florian, Coch, Christoph, Hartmann, Gunther, Poeck, Hendrik (September 2023) Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy. Cell Reports Medicine, 4 (9). p. 101171. ISSN 2666-3791

Heinrich, M. C., Maki, R. G., Corless, C. L., Antonescu, C. R., Harlow, A., Griffith, D., Town, A., McKinley, A., Ou, W. B., Fletcher, J. A., Fletcher, C. D., Huang, X., Cohen, D. P., Baum, C. M., Demetri, G. D. (November 2008) Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor. J Clin Oncol, 26 (33). pp. 5352-9. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Helmrich, A., Lee, S., O'Brien, P., Dorken, B., Lowe, S. W., Schrock, E., Schmitt, C. A. (June 2005) Recurrent chromosomal aberrations in INK4a/ARF defective primary lymphomas predict drug responses in vivo. Oncogene, 24 (26). pp. 4174-4182. ISSN 0950-9232

Hensley, M. L., Maki, R., Venkatraman, E., Geller, G., Lovegren, M., Aghajanian, C., Sabbatini, P., Tong, W., Barakat, R., Spriggs, D. R. (June 2002) Gemcitabine and docetaxel in patients with unresectable leiomyosarcoma: results of a phase II trial. J Clin Oncol, 20 (12). pp. 2824-31. ISSN 0732-183X (Print)0732-183X (Linking)

Hensley, M. L., Patel, S. R., von Mehren, M., Ganjoo, K., Jones, R. L., Staddon, A., Rushing, D., Milhem, M., Monk, B., Wang, G., McCarthy, S., Knoblauch, R. E., Parekh, T. V., Maki, R. G., Demetri, G. D. (September 2017) Efficacy and safety of trabectedin or dacarbazine in patients with advanced uterine leiomyosarcoma after failure of anthracycline-based chemotherapy: Subgroup analysis of a phase 3, randomized clinical trial. Gynecol Oncol, 146 (3). pp. 531-537. ISSN 0090-8258

Hensley, M. L., Wathen, J. K., Maki, R. G., Araujo, D. M., Sutton, G., Priebat, D. A., George, S., Soslow, R. A., Baker, L. H. (April 2013) Adjuvant therapy for high-grade, uterus-limited leiomyosarcoma: results of a phase 2 trial (SARC 005). Cancer, 119 (8). pp. 1555-61. ISSN 1097-0142 (Electronic)0008-543X (Linking)

Herrmann, H., Blatt, K., Shi, J., Gleixner, K. V., Cerny-Reiterer, S., Mullauer, L., Vakoc, C. R., Sperr, W. R., Horny, H. P., Bradner, J. E., Zuber, J., Valent, P. (December 2012) Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML. Oncotarget, 3 (12). pp. 1588-99. ISSN 1949-2553

Hettmer, S., Li, Z., Billin, A. N., Barr, F. G., Cornelison, D. D., Ehrlich, A. R., Guttridge, D. C., Hayes-Jordan, A., Helman, L. J., Houghton, P. J., Khan, J., Langenau, D. M., Linardic, C. M., Pal, R., Partridge, T. A., Pavlath, G. K., Rota, R., Schafer, B. W., Shipley, J., Stillman, B., Wexler, L. H., Wagers, A. J., Keller, C. (November 2014) Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies. Cold Spring Harbor Perspectives in Medicine, 4 (11). ISSN 19430264

Hirschhorn, Daniel, Budhu, Sadna, Kraehenbuehl, Lukas, Gigoux, Mathieu, Schröder, David, Chow, Andrew, Ricca, Jacob M, Gasmi, Billel, De Henau, Olivier, Mangarin, Levi Mark B, Li, Yanyun, Hamadene, Linda, Flamar, Anne-Laure, Choi, Hyejin, Cortez, Czrina A, Liu, Cailian, Holland, Aliya, Schad, Sara, Schulze, Isabell, Betof Warner, Allison, Hollmann, Travis J, Arora, Arshi, Panageas, Katherine S, Rizzuto, Gabrielle A, Duhen, Rebekka, Weinberg, Andrew D, Spencer, Christine N, Ng, David, He, Xue-Yan, Albrengues, Jean, Redmond, David, Egeblad, Mikala, Wolchok, Jedd D, Merghoub, Taha (March 2023) T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants. Cell, 186 (7). 1432-1447.e17. ISSN 0092-8674 (Public Dataset)

Hohmann, A. F., Vakoc, C. R. (June 2014) A rationale to target the SWI/SNF complex for cancer therapy. Trends in Genetics, 30 (8). pp. 356-363. ISSN 01689525

Hou, Shurong, Tiriac, Hervé, Sridharan, Banu Priya, Scampavia, Louis, Madoux, Franck, Seldin, Jan, Souza, Glauco R, Watson, Donald, Tuveson, David, Spicer, Timothy P (July 2018) Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening. Slas Discovery, 23 (6). pp. 574-584. ISSN 2472-5552

Hu, J. S., Durst, M., Kerb, R., Truong, V., Ma, J. T., Khurgin, E., Balaban, D., Gingeras, T. R., Hoffman, B. B. (2000) Analysis of drug pharmacology towards predicting drug behavior by expression profiling using high-density oligonucleotide arrays. Annals of the New York Academy of Sciences, 919. pp. 9-15. ISSN 00778923 (ISSN)

Hu, Tuo, Shukla, Surendra K, Vernucci, Enza, He, Chunbo, Wang, Dezhen, King, Ryan J, Jha, Kanupriya, Siddhanta, Kasturi, Mullen, Nicholas J, Attri, Kuldeep S, Murthy, Divya, Chaika, Nina V, Thakur, Ravi, Mulder, Scott E, Pacheco, Camila G, Fu, Xiao, High, Robin R, Yu, Fang, Lazenby, Audrey, Steegborn, Clemens, Lan, Ping, Mehla, Kamiya, Rotili, Dante, Chaudhary, Sarika, Valente, Sergio, Tafani, Marco, Mai, Antonello, Auwerx, Johan, Verdin, Eric, Tuveson, David, Singh, Pankaj K (July 2021) Metabolic Rewiring by Loss of Sirt5 Promotes Kras-induced Pancreatic Cancer Progression. Gastroenterology. ISSN 0016-5085

Huang, T. H., Wu, A. T. H., Cheng, T. S., Lin, K. T., Lai, C. J., Hsieh, H. W., Chang, P. M. H., Wu, C. W., Huang, C. Y. F., Chen, K. Y. (December 2019) In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non–small-cell lung cancer. Journal of Cellular and Molecular Medicine, 23 (12). pp. 8184-8195. ISSN 15821838 (ISSN)

Hörmann, A., Hopfgartner, B., Köcher, T., Corcokovic, M., Krammer, T., Reiser, C., Bader, G., Shi, J., Ehrenhöfer, K., Wöhrle, S., Schweifer, N., Vakoc, C. R., Kraut, N., Pearson, M., Petronczki, M., Neumüller, R. A. (June 2018) RIOK1 kinase activity is required for cell survival irrespective of MTAP status. Oncotarget, 9 (47). pp. 28625-28637. ISSN 1949-2553

I

Ibrahim, Ayman M, Moss, Matthew A, Gray, Zane, Rojo, Michelle D, Burke, Caitlin M, Schwertfeger, Kathryn L, Dos Santos, Camila O, Machado, Heather L (2020) Diverse Macrophage Populations Contribute to the Inflammatory Microenvironment in Premalignant Lesions During Localized Invasion. Frontiers in Oncology, 10. p. 569985. ISSN 2234-943X

Ipsaro, J. J., Shen, C., Arai, E., Xu, Y., Kinney, J. B., Joshua-Tor, L., Vakoc, C. R., Shi, J. (February 2017) Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis. PLoS One, 12 (2). e0172177. ISSN 1932-6203

Ireland, L., Santos, A., Ahmed, M. S., Rainer, C., Nielsen, S. R., Quaranta, V., Weyer-Czernilofsky, U., Engle, D. D., Perez-Mancera, P., Coupland, S. E., Taktak, A. F., Bogenrieder, T., Tuveson, D. A., Campbell, F., Schmid, M. C., Mielgo, A. (December 2016) Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors. Cancer Res, 76 (23). pp. 6851-6863. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Ishigami, Yuma, Wong, Mandy S, Martí-Gómez, Carlos, Ayaz, Andalus, Kooshkbaghi, Mahdi, Hanson, Sonya, McCandlish, David M, Krainer, Adrian R, Kinney, Justin B (December 2022) Specificity, synergy, and mechanisms of splice-modifying drugs. (Public Dataset) (Submitted)

Italiano, A., Cioffi, A., Coco, P., Maki, R. G., Schoffski, P., Rutkowski, P., Le Cesne, A., Duffaud, F., Adenis, A., Isambert, N., Bompas, E., Blay, J. Y., Casali, P., Keohan, M. L., Toulmonde, M., Antonescu, C. R., Debiec-Rychter, M., Coindre, J. M., Bui, B. (May 2012) Patterns of care, prognosis, and survival in patients with metastatic gastrointestinal stromal tumors (GIST) refractory to first-line imatinib and second-line sunitinib. Ann Surg Oncol, 19 (5). pp. 1551-9. ISSN 1534-4681 (Electronic)1068-9265 (Linking)

Italiano, A., Cioffi, A., Penel, N., Levra, M. G., Delcambre, C., Kalbacher, E., Chevreau, C., Bertucci, F., Isambert, N., Blay, J. Y., Bui, B., Antonescu, C., D'Adamo, D. R., Maki, R. G., Keohan, M. L. (July 2012) Comparison of doxorubicin and weekly paclitaxel efficacy in metastatic angiosarcomas. Cancer, 118 (13). pp. 3330-6. ISSN 1097-0142 (Electronic)0008-543X (Linking)

Italiano, A., Garbay, D., Cioffi, A., Maki, R. G., Bui, B. (August 2012) Advanced pleomorphic liposarcomas: clinical outcome and impact of chemotherapy. Ann Oncol, 23 (8). pp. 2205-6. ISSN 1569-8041 (Electronic)0923-7534 (Linking)

Italiano, A., Kind, M., Cioffi, A., Maki, R. G., Bui, B. (September 2013) Clinical activity of sunitinib in patients with advanced desmoplastic round cell tumor: a case series. Target Oncol, 8 (3). pp. 211-3. ISSN 1776-260X (Electronic)1776-2596 (Linking)

Italiano, A., Mir, O., Cioffi, A., Palmerini, E., Piperno-Neumann, S., Perrin, C., Chaigneau, L., Penel, N., Duffaud, F., Kurtz, J. E., Collard, O., Bertucci, F., Bompas, E., Le Cesne, A., Maki, R. G., Ray Coquard, I., Blay, J. Y. (November 2013) Advanced chondrosarcomas: role of chemotherapy and survival. Ann Oncol, 24 (11). pp. 2916-22. ISSN 1569-8041 (Electronic)0923-7534 (Linking)

Italiano, A., Saada, E., Cioffi, A., Poulette, S., Bouchet, S., Molimard, M., Adenis, A., Isambert, N., Collard, O., Le Cesne, A., Maki, R. G., Bui, B. (December 2013) Treatment of advanced gastrointestinal stromal tumors in patients over 75 years old: clinical and pharmacological implications. Target Oncol, 8 (4). pp. 295-300. ISSN 1776-260X (Electronic)1776-2596 (Linking)

Italiano, A., Toulmonde, M., Cioffi, A., Penel, N., Isambert, N., Bompas, E., Duffaud, F., Patrikidou, A., Lortal, B., Le Cesne, A., Blay, J. Y., Maki, R. G., Schwartz, G. K., Antonescu, C. R., Singer, S., Coindre, J. M., Bui, B. (June 2012) Advanced well-differentiated/dedifferentiated liposarcomas: role of chemotherapy and survival. Ann Oncol, 23 (6). pp. 1601-7. ISSN 1569-8041 (Electronic)0923-7534 (Linking)

J

Jacobetz, M. A., Chan, D. S., Neesse, A., Bapiro, T. E., Cook, N., Frese, K. K., Feig, C., Nakagawa, T., Caldwell, M. E., Zecchini, H. I., Lolkema, M. P., Jiang, P., Kultti, A., Thompson, C. B., Maneval, D. C., Jodrell, D. I., Frost, G. I., Shepard, H. M., Skepper, J. N., Tuveson, D. A. (January 2013) Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut, 62 (1). pp. 112-20. ISSN 1468-3288 (Electronic)0017-5749 (Linking)

Janowitz, Tobias, Kleeman, Sam, Vonderheide, Robert H (April 2021) Reconsidering Dexamethasone for Antiemesis when Combining Chemotherapy and Immunotherapy. The Oncologist, 26 (4). pp. 269-273. ISSN 1083-7159

Jones, R. L., Chawla, S. P., Attia, S., Schoffski, P., Gelderblom, H., Chmielowski, B., Le Cesne, A., Van Tine, B. A., Trent, J. C., Patel, S., Wagner, A. J., Chugh, R., Heyburn, J. W., Weil, S. C., Wang, W., Viele, K., Maki, R. G. (April 2019) A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb-004) in metastatic soft-tissue sarcomas. Cancer, 125 (14). pp. 2445-2454. ISSN 0008-543x

Jones, R. L., Constantinidou, A., Thway, K., Ashley, S., Scurr, M., Al-Muderis, O., Fisher, C., Antonescu, C. R., D'Adamo, D. R., Keohan, M. L., Maki, R. G., Judson, I. R. (September 2011) Chemotherapy in clear cell sarcoma. Med Oncol, 28 (3). pp. 859-63. ISSN 1559-131X (Electronic)1357-0560 (Linking)

Judge, SJ, Ji, J, Liu, J, Kaur, M, Kim, E, Gong, J, Tam, KW, Kirane, AR, Gholami, S, Canter, RJ, Bold, RJ, Gangi, A, Fakih, M, Cho, M (April 2020) The Role of Palliative Surgery for Malignant Bowel Obstruction and Perforation in Advanced Microsatellite Instability-High Colorectal Carcinoma in the Era of Immunotherapy: Case Report. Frontiers in Oncology, 10. ISSN 2234-943X

Judge, Sean J, Cho, May, Gholami, Sepideh (November 2022) Genomic Predictors of Recurrence Patterns After Complete Resection of Colorectal Liver Metastases and Adjuvant Hepatic Artery Infusion Chemotherapy by Narayan et al. Annals of Surgical Oncology, 29 (12). pp. 7246-7247. ISSN 1068-9265

K

Kagan, J., Moritz, R. L., Mazurchuk, R., Lee, J. H., Kharchenko, P. V., Rozenblatt-Rosen, O., Ruppin, E., Edfors, F., Ginty, F., Goltsev, Y., Wells, J. A., LaCava, J., Riesterer, J. L., Germain, R. N., Shi, T., Chee, M. S., Budnik, B. A., Yates, J. R., Chait, B. T., Moffitt, J. R., Smith, R. D., Srivastava, S. (May 2020) National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions. J Proteome Res, 19 (5). pp. 1900-1912. ISSN 1535-3893

Katt, W. P., Lukey, M. J., Cerione, R. A. (September 2019) Starving the Devourer: Cutting Cancer Off from Its Favorite Foods. Cell Chem Biol, 26 (9). pp. 1197-1199. ISSN 2451-9448

Kawaguchi, Risa K., Takahashi, Masamichi, Miyake, Mototaka, Kinoshita, Manabu, Takahashi, Satoshi, Ichimura, Koichi, Hamamoto, Ryuji, Narita, Yoshitaka, Sese, Jun (July 2021) Assessing Versatile Machine Learning Models for Glioma Radiogenomic Studies across Hospitals. Cancers, 13 (14). p. 3611. ISSN 2072-6694

Kleeman, Sam O, Thakir, Tuba Mansoor, Demestichas, Breanna, Mourikis, Nicholas, Loiero, Dominik, Ferrer, Miriam, Bankier, Sean, Riazat-Kesh, Yosef JRA, Lee, Hassal, Chantzichristos, Dimitrios, Regan, Claire, Preall, Jonathan, Sinha, Sarthak, Rosin, Nicole, Yipp, Bryan, de Almeida, Luiz GN, Biernaskie, Jeff, Dufour, Antoine, Tober-Lau, Pinkus, Ruusalepp, Arno, Bjorkegren, Johan LM, Ralser, Markus, Kurth, Florian, Demichev, Vadim, Heywood, Todd, Gao, Qing, Johannsson, Gudmundur, Koelzer, Viktor H, Walker, Brian R, Meyer, Hannah V, Janowitz, Tobias (August 2023) Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy. Cell Genomics, 3 (8). p. 100347. ISSN 2666-979X

Kortmansky, J., Shah, M. A., Kaubisch, A., Weyerbacher, A., Yi, S., Tong, W., Sowers, R., Gonen, M., O'Reilly, E., Kemeny, N., Ilson, D. I., Saltz, L. B., Maki, R. G., Kelsen, D. P., Schwartz, G. K. (March 2005) Phase I trial of the cyclin-dependent kinase inhibitor and protein kinase C inhibitor 7-hydroxystaurosporine in combination with Fluorouracil in patients with advanced solid tumors. J Clin Oncol, 23 (9). pp. 1875-84. ISSN 0732-183X (Print)0732-183X (Linking)

Kotani, Daisuke, Nakamura, Yoshiaki, Fujisawa, Takao, Bando, Hideaki, Sakamoto, Naoya, Johns, Amber L, Park, Keunchil, ICGC-ARGO, Casolino, Raffaella, Yoshino, Takayuki, Biankin, Andrew V (April 2022) ICGC-ARGO precision medicine: targeted therapy according to longitudinal assessment of tumour heterogeneity in colorectal cancer. The Lancet Oncology, 23 (4). pp. 463-464. ISSN 1470-2045

Krishnan, N., Koveal, D., Miller, D. H., Xue, B., Akshinthala, S. D., Kragelj, J., Jensen, M. R., Gauss, C. M., Page, R., Blackledge, M., Muthuswamy, S. K., Peti, W., Tonks, N. K. (May 2014) Targeting the disordered C terminus of PTP1B with an allosteric inhibitor. Nature Chemical Biology, 10 (7). pp. 558-566. ISSN 15524450

Ku, G. Y., O'Reilly, E. M., Saltz, L. B., Schrag, D., Maki, R. G., Kelsen, D. P., Ilson, D. H. (May 2009) Phase I study of weekly cisplatin, bolus fluorouracil and escalating doses of irinotecan in advanced solid tumors. Cancer Invest, 27 (4). pp. 402-6. ISSN 1532-4192 (Electronic)0735-7907 (Linking)

Kuritzkes, D. R., Shugarts, D., Bakhtiari, M., Poticha, D., Johnson, J., Rubin, M., Gingeras, T. R., Kennedy, M., Eron, J. J. (2000) Emergence of dual resistance to zidovudine and lamivudine in HIV-1- infected patients treated with zidovudine plus lamivudine as initial therapy. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, 23 (1). pp. 26-34. ISSN 10779450 (ISSN)

Kwak, E. L., Bang, Y. J., Camidge, D. R., Shaw, A. T., Solomon, B., Maki, R. G., Ou, S. H., Dezube, B. J., Janne, P. A., Costa, D. B., Varella-Garcia, M., Kim, W. H., Lynch, T. J., Fidias, P., Stubbs, H., Engelman, J. A., Sequist, L. V., Tan, W., Gandhi, L., Mino-Kenudson, M., Wei, G. C., Shreeve, S. M., Ratain, M. J., Settleman, J., Christensen, J. G., Haber, D. A., Wilner, K., Salgia, R., Shapiro, G. I., Clark, J. W., Iafrate, A. J. (October 2010) Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med, 363 (18). pp. 1693-703. ISSN 1533-4406 (Electronic)0028-4793 (Linking)

Kwak, E. L., Sordella, R., Bell, D. W., Godin-Heymann, N., Okimoto, R. A., Brannigan, B. W., Harris, P. L., Driscoll, D. R., Fidias, P., Lynch, T. J., Rabindran, S. K., McGinnis, J. P., Wissner, A., Sharma, S. V., Isselbacher, K. J., Settleman, J., Haber, D. A. (May 2005) Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proceedings of the National Academy of Sciences of the United States of America, 102 (21). pp. 7665-70. ISSN 0027-8424

L

Latcha, S., Maki, R. G., Schwartz, G. K., Flombaum, C. D. (2009) Ifosfamide may be safely used in patients with end stage renal disease on hemodialysis. Sarcoma, 2009. p. 575629. ISSN 1369-1643 (Electronic)1357-714X (Linking)

Le Cesne, A., Cresta, S., Maki, R. G., Blay, J. Y., Verweij, J., Poveda, A., Casali, P. G., Balana, C., Schoffski, P., Grosso, F., Lardelli, P., Nieto, A., Alfaro, V., Demetri, G. D. (November 2012) A retrospective analysis of antitumour activity with trabectedin in translocation-related sarcomas. Eur J Cancer, 48 (16). pp. 3036-44. ISSN 1879-0852 (Electronic)0959-8049 (Linking)

Le Cesne, A., Yovine, A., Blay, J. Y., Delaloge, S., Maki, R. G., Misset, J. L., Frontelo, P., Nieto, A., Jiao, J. J., Demetri, G. D. (June 2012) A retrospective pooled analysis of trabectedin safety in 1,132 patients with solid tumors treated in phase II clinical trials. Invest New Drugs, 30 (3). pp. 1193-202. ISSN 1573-0646 (Electronic)0167-6997 (Linking)

Lee, C. K., Goldstein, D., Gibbs, E., Joensuu, H., Zalcberg, J., Verweij, J., Casali, P. G., Maki, R. G., Cioffi, A., McArthur, G., Lord, S. J., Yip, D., Kanjanapan, Y., Rutkowski, P. (May 2015) Development and validation of prognostic nomograms for metastatic gastrointestinal stromal tumour treated with imatinib. Eur J Cancer, 51 (7). pp. 852-60. ISSN 1879-0852 (Electronic)0959-8049 (Linking)

Lee, H. J., Li, C. F., Ruan, D., Powers, S., Thompson, P. A., Frohman, M. A., Chan, C. H. (September 2016) The DNA Damage Transducer RNF8 Facilitates Cancer Chemoresistance and Progression through Twist Activation. Mol Cell, 63 (6). pp. 1021-33. ISSN 1097-2765

Li, Jiayun, Moresco, Philip, Fearon, Douglas T (July 2024) Intratumoral NKT cell accumulation promotes antitumor immunity in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 121 (29). e2403917121. ISSN 0027-8424 (Public Dataset)

Li, Bing, An, Wenbin, Wang, Hua, Baslan, Timour, Mowla, Shoron, Krishnan, Aishwarya, Xiao, Wenbin, Koche, Richard Patrick, Liu, Ying, Cai, Sheng F, Xiao, Zhijian, Derkach, Andriy, Iacobucci, Ilaria, Mullighan, Charles G, Helin, Kristian, Lowe, Scott W, Levine, Ross L, Rampal, Raajit K (April 2022) BMP2/SMAD pathway activation in JAK2/p53-mutant Megakaryocyte/Erythroid Progenitors Promotes Leukemic Transformation. Blood. ISSN 0006-4971

Lowe, S; Zhang, L; Chen, C (October 2020) Compositions and methods for treating acute myeloid leukemia. .

Luke, J. J., D'Adamo, D. R., Dickson, M. A., Keohan, M. L., Carvajal, R. D., Maki, R. G., de Stanchina, E., Musi, E., Singer, S., Schwartz, G. K. (May 2012) The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial. Clin Cancer Res, 18 (9). pp. 2638-47. ISSN 1078-0432 (Print)1078-0432 (Linking)

Lukey, M. J., Cluntun, A. A., Katt, W. P., Lin, M. J., Druso, J. E., Ramachandran, S., Erickson, J. W., Le, H. H., Wang, Z. E., Blank, B., Greene, K. S., Cerione, R. A. (October 2019) Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer. Cell Rep, 29 (1). 76-88 e7. ISSN 2211-1247

Lukey, M. J., Katt, W. P., Cerione, R. A. (May 2018) Targeting Therapy Resistance: When Glutamine Catabolism Becomes Essential. Cancer Cell, 33 (5). pp. 795-797. ISSN 1878-3686

Lukey, M. J., Katt, W. P., Cerione, R. A. (May 2017) Targeting amino acid metabolism for cancer therapy. Drug Discov Today, 22 (5). pp. 796-804. ISSN 1878-5832

Lukow, Devon A, Sausville, Erin L, Suri, Pavit, Chunduri, Narendra Kumar, Wieland, Angela, Leu, Justin, Smith, Joan C, Girish, Vishruth, Kumar, Ankith A, Kendall, Jude, Wang, Zihua, Storchova, Zuzana, Sheltzer, Jason M (August 2021) Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies. Developmental Cell. ISSN 1534-5807

Lukow, Devon A, Sheltzer, Jason M (September 2021) Chromosomal instability and aneuploidy as causes of cancer drug resistance. Trends in Cancer. ISSN 2405-8033

Lynch, T. J., Bell, D. W., Sordella, R., Gurubhagavatula, S., Okimoto, R. A., Brannigan, B. W., Harris, P. L., Haserlat, S. M., Supko, J. G., Haluska, F. G., Louis, D. N., Christiani, D. C., Settleman, J., Haber, D. A. (May 2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. The New England Journal of Medicine, 350 (21). pp. 2129-39. ISSN 1533-4406 (Electronic)

M

MacDiarmid, J. A., Langova, V., Bailey, D., Pattison, S. T., Pattison, S. L., Christensen, N., Armstrong, L. R., Brahmbhatt, V. N., Smolarczyk, K., Harrison, M. T., Costa, M., Mugridge, N. B., Sedliarou, I., Grimes, N. A., Kiss, D. L., Stillman, B., Hann, C. L., Gallia, G. L., Graham, R. M., Brahmbhatt, H. (April 2016) Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model. PLoS One, 11 (4). e0151832. ISSN 1932-6203 (Electronic)1932-6203 (Linking)

MacDiarmid, J. A., Amaro-Mugridge, N. B., Madrid-Weiss, J., Sedliarou, I., Wetzel, S., Kochar, K., Brahmbhatt, V. N., Phillips, L., Pattison, S. T., Petti, C., Stillman, B., Graham, R. M., Brahmbhatt, H. (June 2009) Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug. Nature Biotechnology, 27 (7). pp. 643-651. ISSN 1087-0156

Maiorino, L., Egeblad, M. (August 2019) Tumours pick the path to cancer inflammation. Nat Cell Biol, 21 (9). pp. 1055-1057. ISSN 1465-7392

Maiorino, Laura, Daßler-Plenker, Juliane, Sun, Lijuan, Egeblad, Mikala (November 2021) Innate Immunity and Cancer Pathophysiology. Annual Review of Pathology: Mechanisms of Disease, 17 (1). ISSN 1553-4006

Maki, R. G., Awan, R. A., Dixon, R. H., Jhanwar, S., Antonescu, C. R. (August 2002) Differential sensitivity to imatinib of 2 patients with metastatic sarcoma arising from dermatofibrosarcoma protuberans. Int J Cancer, 100 (6). pp. 623-6. ISSN 0020-7136 (Print)0020-7136 (Linking)

Maki, R. G., D'Adamo, D. R., Keohan, M. L., Saulle, M., Schuetze, S. M., Undevia, S. D., Livingston, M. B., Cooney, M. M., Hensley, M. L., Mita, M. M., Takimoto, C. H., Kraft, A. S., Elias, A. D., Brockstein, B., Blachere, N. E., Edgar, M. A., Schwartz, L. H., Qin, L. X., Antonescu, C. R., Schwartz, G. K. (July 2009) Phase II study of sorafenib in patients with metastatic or recurrent sarcomas. J Clin Oncol, 27 (19). pp. 3133-40. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Maki, R. G., Jungbluth, A. A., Gnjatic, S., Schwartz, G. K., D'Adamo, D. R., Keohan, M. L., Wagner, M. J., Scheu, K., Chiu, R., Ritter, E., Kachel, J., Lowy, I., Old, L. J., Ritter, G. (2013) A Pilot Study of Anti-CTLA4 Antibody Ipilimumab in Patients with Synovial Sarcoma. Sarcoma, 2013. p. 168145. ISSN 1357-714X (Print)1357-714X (Linking)

Maki, R. G., Kraft, A. S., Scheu, K., Yamada, J., Wadler, S., Antonescu, C. R., Wright, J. J., Schwartz, G. K. (April 2005) A multicenter Phase II study of bortezomib in recurrent or metastatic sarcomas. Cancer, 103 (7). pp. 1431-8. ISSN 0008-543X (Print)0008-543X (Linking)

Maki, R. G., Wathen, J. K., Patel, S. R., Priebat, D. A., Okuno, S. H., Samuels, B., Fanucchi, M., Harmon, D. C., Schuetze, S. M., Reinke, D., Thall, P. F., Benjamin, R. S., Baker, L. H., Hensley, M. L. (July 2007) Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas: results of sarcoma alliance for research through collaboration study 002 [corrected]. J Clin Oncol, 25 (19). pp. 2755-63. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Manchado, E., Huang, C. H., Tasdemir, N., Tschaharganeh, D. F., Wilkinson, J. E., Lowe, S. W. (January 2017) A Pipeline for Drug Target Identification and Validation. Cold Spring Harb Symp Quant Biol, 81. pp. 257-267. ISSN 1943-4456 (Electronic)0091-7451 (Linking)

Martinelli, S., Kostylina, G., Niggli, V., Baumann, C., Fey, M. F., Wendel, H. G., Lowe, S. W., Yousefi, S., Simon, H. U. (2006) Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. Oncogene, 25 (52). pp. 6915-6923. ISSN 09509232

McCarter, M. D., Antonescu, C. R., Ballman, K. V., Maki, R. G., Pisters, P. W., Demetri, G. D., Blanke, C. D., von Mehren, M., Brennan, M. F., McCall, L., Ota, D. M., DeMatteo, R. P., American College of Surgeons Oncology Group Intergroup Adjuvant , Team (July 2012) Microscopically positive margins for primary gastrointestinal stromal tumors: analysis of risk factors and tumor recurrence. J Am Coll Surg, 215 (1). 53-9; discussion 59. ISSN 1879-1190 (Electronic)1072-7515 (Linking)

McDermott, U., Sharma, S. V., Dowell, L., Greninger, P., Montagut, C., Lamb, J., Archibald, H., Raudales, R., Tam, A., Lee, D., Rothenberg, S. M., Supko, J. G., Sordella, R., Ulkus, L. E., Iafrate, A. J., Maheswaran, S., Njauw, C. N., Tsao, H., Drew, L., Hanke, J. H., Ma, X. J., Erlander, M. G., Gray, N. S., Haber, D. A., Settleman, J. (December 2007) Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. Proceedings of the National Academy of Sciences of the United States of America, 104 (50). pp. 19936-41. ISSN 0027-8424

Mellman, I., Hubbard-Lucey, V. M., Tontonoz, M. J., Kalos, M. D., Chen, D. S., Allison, J. P., Drake, C. G., Levitsky, H., Lonberg, N., van der Burg, S. H., Fearon, D. T., Wherry, E. J., Lowy, I., Vonderheide, R. H., Hwu, P. (April 2016) De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute. Cancer Immunol Res, 4 (4). pp. 279-88. ISSN 2326-6074 (Electronic)2326-6066 (Linking)

Milella, M, Luchini, C, Lawlor, RT, Johns, AL, Casolino, R, Yoshino, T, Biankin, AV, Stein, LD, Park, K, Korbel, JO, Zeps, N, Rubin, MA, Marra, MA, Elemento, O, Gallinger, S, Tuveson, D, Trumper, L, Koch, R, Scarpa, A, Brennan, P, Pilarsky, C, Nikolaev, S, Yoon, SS, Lee, ES, Shibata, T, Wu, X, Wu, J, Zhan, Q, Poon, W, Al-Kuraya, KS, Eeles, R, Fitzgerald, R, Caldas, C, Abraham, J, Chang, DK (January 2022) ICGC-ARGO precision medicine: familial matters in pancreatic cancer. The Lancet Oncology, 23 (1). pp. 25-26. ISSN 1470-2045

Moral, J.A., Leung, J., Rojas, L.A., Ruan, J., Zhao, J., Sethna, Z., Ramnarain, A., Gasmi, B., Gururajan, M., Redmond, D., Askan, G., Bhanot, U., Elyada, E., Park, Y., Tuveson, D. A., Gonen, M., Leach, S.D., Wolchok, J.D., DeMatteo, R. P., Merghoub, T., Balachandran, V. P. (February 2020) ILC2s Amplify PD-1 Blockade by Activating Tissue-Specific Cancer Immunity. Nature, 579 (7797). pp. 130-135. ISSN 0028-0836 (Public Dataset)

Morris, Van K, Kennedy, Erin B, Baxter, Nancy N, Benson, Al B, Cercek, Andrea, Cho, May, Ciombor, Kristen K, Cremolini, Chiara, Davis, Anjee, Deming, Dustin A, Fakih, Marwan G, Gholami, Sepideh, Hong, Theodore S, Jaiyesimi, Ishmael, Klute, Kelsey, Lieu, Christopher, Sanoff, Hanna, Strickler, John H, White, Sarah, Willis, Jason A, Eng, Cathy (January 2023) Treatment of Metastatic Colorectal Cancer: ASCO Guideline. Journal of Clinical Oncology, 41 (3). pp. 678-700. ISSN 0732-183X

Mulloy, R., Ferrand, A., Kim, Y., Sordella, R., Bell, D. W., Haber, D. A., Anderson, K. S., Settleman, J. (March 2007) Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib. Cancer Research, 67 (5). pp. 2325-30. ISSN 0008-5472

N

Nadella, Sandeep, Lieb, John G (January 2022) Minimal Change Patients Versus Obvious Chronic Pancreatitis: A Comparison of Classical Secretin Stimulation Testing Results. Pancreas, 51 (1). pp. 75-79. ISSN 0885-3177

Nakasone, E., Askautrud, H., Kees, T., Park, J., Fein, M., Egeblad, M. (February 2013) Imaging contributions of the microenvironment to chemoresistance. Journal of Nuclear Medicine, 54 (Supple). p. 31. ISSN 0161-5505

Nakasone, E. S., Askautrud, H. A., Kees, T., Park, J. H., Plaks, V., Ewald, A. J., Fein, M., Rasch, M. G., Tan, Y. X., Qiu, J., Park, J., Sinha, P., Bissell, M. J., Frengen, E., Werb, Z., Egeblad, M. (April 2012) Imaging Tumor-Stroma Interactions during Chemotherapy Reveals Contributions of the Microenvironment to Resistance. Cancer Cell, 21 (4). pp. 488-503. ISSN 1535-6108

Narita, M., Narita, M., Krizhanovsky, V., Nunez, S., Chicas, A., Hearn, S. A., Myers, M. P., Lowe, S. W. (August 2006) A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation. Cell, 126 (3). pp. 503-14. ISSN 0092-8674 (Print)

Neesse, A., Frese, K. K., Bapiro, T. E., Nakagawa, T., Sternlicht, M. D., Seeley, T. W., Pilarsky, C., Jodrell, D. I., Spong, S. M., Tuveson, D. A. (July 2013) CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America, 110 (30). pp. 12325-30. ISSN 0027-8424

Neesse, A., Frese, K. K., Chan, D. S., Bapiro, T. E., Howat, W. J., Richards, F. M., Ellenrieder, V., Jodrell, D. I., Tuveson, D. A. (September 2013) SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice. Gut, 63 (6). pp. 974-983. ISSN 00175749 (ISSN)

Neesse, A., Krug, S., Gress, T. M., Tuveson, D. A., Michl, P. (2013) Emerging concepts in pancreatic cancer medicine: targeting the tumor stroma. Onco Targets Ther, 7. pp. 33-43. ISSN 1178-6930 (Print)1178-6930

Neesse, A., Michl, P., Tuveson, D. A., Ellenrieder, V. (April 2014) nab-Paclitaxel: Novel Clinical and Experimental Evidence in Pancreatic Cancer. Zeitschrift fur Gastroenterologie, 52 (4). pp. 360-366. ISSN 0044-2771

Nielsen, Sebastian R, Strøbech, Jan E, Horton, Edward R, Jackstadt, Rene, Laitala, Anu, Bravo, Marina C, Maltese, Giorgia, Jensen, Adina RD, Reuten, Raphael, Rafaeva, Maria, Karim, Saadia A, Hwang, Chang-Il, Arnes, Luis, Tuveson, David A, Sansom, Owen J, Morton, Jennifer P, Erler, Janine T (June 2021) Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade. Nature Communications, 12 (1). p. 3414. ISSN 2041-1723

Nocini, Riccardo, Tondulli, Luca, D'Ambrosio, Consuelo, Luchini, Claudio, Biankin, Andrew V, Casolino, Raffaella, Scarpa, Aldo, ICGC-ARGO, Milella, Michele, Lawlor, Rita T (August 2023) ICGC ARGO precision medicine: genomic profiling-informed prediction of immunotherapy response in two patients with metastatic head and neck squamous cell carcinoma. The Lancet Oncology, 24 (8). pp. 851-853. ISSN 1470-2045

Norden-Zfoni, A., Desai, J., Manola, J., Beaudry, P., Force, J., Maki, R., Folkman, J., Bello, C., Baum, C., DePrimo, S. E., Shalinsky, D. R., Demetri, G. D., Heymach, J. V. (May 2007) Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor. Clin Cancer Res, 13 (9). pp. 2643-50. ISSN 1078-0432 (Print)1078-0432 (Linking)

Norton, Larry (October 2021) IS THE MAXIMUM TOLERATED DOSE (MDT) STILL THE OPTIMAL GOAL FOR CANCER DRUGS? In: UNSPECIFIED.

O

Ohlund, D., Elyada, E., Tuveson, D. (July 2014) Fibroblast heterogeneity in the cancer wound. Journal of Experimental Medicine, 211 (8). pp. 1503-23. ISSN 0022-1007

Ohman, K. A., Hashim, Y. M., Vangveravong, S., Nywening, T. M., Cullinan, D. R., Goedegebuure, S. P., Liu, J., Van Tine, B. A., Tiriac, H., Tuveson, D. A., DeNardo, D. G., Spitzer, D., Mach, R. H., Hawkins, W. G. (June 2016) Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic. Oncotarget, 7 (23). pp. 33529-33541. ISSN 1949-2553 (Electronic)1949-2553 (Linking)

Ou, S. H., Bazhenova, L., Camidge, D. R., Solomon, B. J., Herman, J., Kain, T., Bang, Y. J., Kwak, E. L., Shaw, A. T., Salgia, R., Maki, R. G., Clark, J. W., Wilner, K. D., Iafrate, A. J. (December 2010) Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer. J Thorac Oncol, 5 (12). pp. 2044-6. ISSN 1556-1380 (Electronic)1556-0864 (Linking)

Ou, S. H., Kwak, E. L., Siwak-Tapp, C., Dy, J., Bergethon, K., Clark, J. W., Camidge, D. R., Solomon, B. J., Maki, R. G., Bang, Y. J., Kim, D. W., Christensen, J., Tan, W., Wilner, K. D., Salgia, R., Iafrate, A. J. (May 2011) Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification. J Thorac Oncol, 6 (5). pp. 942-6. ISSN 1556-1380 (Electronic)1556-0864 (Linking)

P

Paffenholz, Stella V, Salvagno, Camilla, Ho, Yu-Jui, Limjoco, Matthew, Baslan, Timour, Tian, Sha, Kulick, Amanda, de Stanchina, Elisa, Wilkinson, John E, Barriga, Francisco M, Zamarin, Dmitriy, Cubillos-Ruiz, Juan R, Leibold, Josef, Lowe, Scott W (February 2022) Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer. Proceedings of the National Academy of Sciences of USA, 119 (5). e2117754119-e2117754119. ISSN 0027-8424

Page, David B, Beal, Kathryn, Linch, Stefanie N, Spinelli, Kateri J, Rodine, Micaela, Halpenny, Darragh, Modi, Shanu, Patil, Sujata, Young, Robert J, Kaley, Thomas, Merghoub, Taha, Redmond, David, Wong, Phillip, Barker, Christopher A, Diab, Adi, Norton, Larry, McArthur, Heather L (April 2022) Brain radiotherapy, tremelimumab-mediated CTLA-4-directed blockade +/- trastuzumab in patients with breast cancer brain metastases. npj Breast Cancer, 8 (1). p. 50. ISSN 2374-4677

Palm, W., Park, Y., Wright, K., Pavlova, N. N., Tuveson, D. A., Thompson, C. B. (July 2015) The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1. Cell, 162 (2). pp. 259-270. ISSN 1097-4172 (Electronic)0092-8674 (Linking)

Palmerini, E., Maki, R. G., Staals, E. L., Alberghini, M., Antonescu, C. R., Ferrari, C., Ruggieri, P., Mavrogenis, A., Bertoni, F., Cesari, M., Paioli, A., Marchesi, E., Picci, P., Ferrari, S. (December 2014) Primary angiosarcoma of bone: a retrospective analysis of 60 patients from 2 institutions. Am J Clin Oncol, 37 (6). pp. 528-34. ISSN 1537-453X (Electronic)0277-3732 (Linking)

Pappo, A. S., Patel, S. R., Crowley, J., Reinke, D. K., Kuenkele, K. P., Chawla, S. P., Toner, G. C., Maki, R. G., Meyers, P. A., Chugh, R., Ganjoo, K. N., Schuetze, S. M., Juergens, H., Leahy, M. G., Geoerger, B., Benjamin, R. S., Helman, L. J., Baker, L. H. (December 2011) R1507, a monoclonal antibody to the insulin-like growth factor 1 receptor, in patients with recurrent or refractory Ewing sarcoma family of tumors: results of a phase II Sarcoma Alliance for Research through Collaboration study. J Clin Oncol, 29 (34). pp. 4541-7. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Pappo, A. S., Vassal, G., Crowley, J. J., Bolejack, V., Hogendoorn, P. C., Chugh, R., Ladanyi, M., Grippo, J. F., Dall, G., Staddon, A. P., Chawla, S. P., Maki, R. G., Araujo, D. M., Geoerger, B., Ganjoo, K., Marina, N., Blay, J. Y., Schuetze, S. M., Chow, W. A., Helman, L. J. (August 2014) A phase 2 trial of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF-1R), in patients with recurrent or refractory rhabdomyosarcoma, osteosarcoma, synovial sarcoma, and other soft tissue sarcomas: results of a Sarcoma Alliance for Research Through Collaboration study. Cancer, 120 (16). pp. 2448-56. ISSN 1097-0142 (Electronic)0008-543X (Linking)

Pardee, T., Zuber, J., Lowe, S. W. (November 2009) The Flt3 ITD Accelerates An Already Established Myeloid Leukemia and Alters Chemotherapy Response In Vitro and In Vivo in a p53 Dependent Manner. Blood, 114 (22). p. 685. ISSN 0006-4971

Pardee, T. S., Zuber, J., Lowe, S. W. (May 2009) Effects of the Flt3 ITD on response to chemotherapy in a murine model of acute myeloid leukemia. Journal of Clinical Oncology, 27 (15). p. 7060. ISSN 0732-183X

Patel, T. V., Morgan, J. A., Demetri, G. D., George, S., Maki, R. G., Quigley, M., Humphreys, B. D. (February 2008) A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib. J Natl Cancer Inst, 100 (4). pp. 282-4. ISSN 1460-2105 (Electronic)0027-8874 (Linking)

Penel, N., Demetri, G. D., Blay, J. Y., Cousin, S., Maki, R. G., Chawla, S. P., Judson, I., von Mehren, M., Schoffski, P., Verweij, J., Casali, P., Rodenhuis, S., Schutte, H. J., Cassar, A., Gomez, J., Nieto, A., Zintl, P., Pontes, M. J., Le Cesne, A. (February 2013) Growth modulation index as metric of clinical benefit assessment among advanced soft tissue sarcoma patients receiving trabectedin as a salvage therapy. Ann Oncol, 24 (2). pp. 537-42. ISSN 1569-8041 (Electronic)0923-7534 (Linking)

Petruzzelli, M, Ferrer, M, Schuijs, MJ, Kleeman, SO, Mourikis, N, Hall, Z, Perera, D, Raghunathan, S, Vacca, M, Gaude, E, Lukey, MJ, Jodrell, DI, Frezza, C, Wagner, EF, Venkitaraman, AR, Halim, TYF, Janowitz, T (February 2022) Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia. Cancers, 14 (4). p. 963. ISSN 2072-6694

Piccart, Martine J, Hilbers, Florentine S, Bliss, Judith M, Caballero, Carmela, Frank, Elizabeth S, Renault, Patrick, Naït Kaoudjt, Rachida, Schumacher, Eva, Spears, Patricia A, Regan, Meredith M, Gelber, Richard D, Davidson, Nancy E, Norton, Larry, Winer, Eric P, BIG-NABCG Collaboration (December 2020) Road Map to Safe and Well-Designed De-escalation Trials of Systemic Adjuvant Therapy for Solid Tumors. Journal of Clinical Oncology, 38 (34). pp. 4120-4129. ISSN 0732-183X

Pisters, P. W., O'Sullivan, B., Maki, R. G. (March 2007) Evidence-based recommendations for local therapy for soft tissue sarcomas. J Clin Oncol, 25 (8). pp. 1003-8. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Poirier, J. T., George, J., Owonikoko, T. K., Berns, A., Brambilla, E., Byers, L. A., Carbone, D., Chen, H. J., Christensen, C. L., Dive, C., Farago, A. F., Govindan, R., Hann, C., Hellmann, M. D., Horn, L., Johnson, J. E., Ju, Y. S., Kang, S., Krasnow, M., Lee, J., Lee, S. H., Lehman, J., Lok, B., Lovly, C., MacPherson, D., McFadden, D., Minna, J., Oser, M., Park, K., Park, K. S., Pommier, Y., Quaranta, V., Ready, N., Sage, J., Scagliotti, G., Sos, M. L., Sutherland, K. D., Travis, W. D., Vakoc, C. R., Wait, S. J., Wistuba, I., Wong, K. K., Zhang, H., Daigneault, J., Wiens, J., Rudin, C. M., Oliver, T. G. (April 2020) New Approaches to SCLC Therapy: From the Laboratory to the Clinic. J Thorac Oncol, 15 (4). pp. 520-540. ISSN 1556-0864 (Print)1556-0864

Poirier, J. T., George, J., Owonikoko, T. K., Berns, A., Brambilla, E., Byers, L. A., Carbone, D., Chen, H. J., Christensen, C. L., Dive, C., Farago, A. F., Govindan, R., Hann, C., Hellmann, M. D., Horn, L., Johnson, J. E., Ju, Y. S., Kang, S., Krasnow, M., Lee, J., Lee, S. H., Lehman, J., Lok, B., Lovly, C., MacPherson, D., McFadden, D., Minna, J., Oser, M., Park, K., Park, K. S., Pommier, Y., Quaranta, V., Ready, N., Sage, J., Scagliotti, G., Sos, M. L., Sutherland, K. D., Travis, W. D., Vakoc, C. R., Wait, S. J., Wistuba, I., Wong, K. K., Zhang, H., Daigneault, J., Wiens, J., Rudin, C. M., Oliver, T. G. (February 2020) New approaches to small cell lung cancer therapy : from the laboratory to the clinic. J Thorac Oncol. ISSN 1556-0864

Ponz-Sarvise, M., Corbo, V., Ohlund, D., Oni, T., Handly-Santana, A., Engle, D., Tiriac, H., Chio, C., Feigin, M., Baker, L., Ardito-Abraham, C., Park, Y., Hwang, C., Elyada, E., Yu, K., Clevers, H., Tuveson, D. A. (November 2014) Pancreatic ductal organoids as a new platform for drug discovery. European Journal of Cancer, 50. p. 63. ISSN 0959-8049

Pronier, Elodie, Cifani, Paolo, Merlinsky, Tiffany R, Berman, Katharine Barr, Somasundara, Amritha Varshini Hanasoge, Rampal, Raajit K, LaCava, John, Wei, Karen E, Pastore, Friederike, Maag, Jesper LV, Park, Jane, Koche, Richard, Kentsis, Alex, Levine, Ross L (November 2018) Targeting the CALR interactome in myeloproliferative neoplasms. JCI Insight, 3 (22). ISSN 2379-3708

Puchalski, T. A., Ryan, D. P., Garcia-Carbonero, R., Demetri, G. D., Butkiewicz, L., Harmon, D., Seiden, M. V., Maki, R. G., Lopez-Lazaro, L., Jimeno, J., Guzman, C., Supko, J. G. (October 2002) Pharmacokinetics of ecteinascidin 743 administered as a 24-h continuous intravenous infusion to adult patients with soft tissue sarcomas: associations with clinical characteristics, pathophysiological variables and toxicity. Cancer Chemother Pharmacol, 50 (4). pp. 309-19. ISSN 0344-5704 (Print)0344-5704 (Linking)

R

Raby, S, Connell, C, Janowitz, T (April 2016) A comprehensive analysis of immuno- and immunoradiotherapy trial design developments from 2000-2014. In: ESTRO.

Rallis, KS, Kleeman, SO, Grant, M, Ordidge, KL, Sahdev, A, Powles, T (January 2021) Radiomics for Renal Cell Carcinoma: Predicting Outcomes from Immunotherapy and Targeted Therapies—A Narrative Review. European Urology Focus. ISSN 2405-4569

Rapp, S., Baader, M., Hu, M., Jennen-Steinmetz, C., Henn, F. A., Thome, J. (2004) Differential regulation of synaptic vesicle proteins by antidepressant drugs. Pharmacogenomics J, 4 (2). pp. 110-3. ISSN 1470-269X (Print)1470-269X (Linking)

Richman, D. D., Guatelli, J. C., Grimes, J., Tsiatis, A., Gingeras, T. R. (1991) Detection of mutations associated with zidovudine resistance in human immunodeficiency virus by use of the polymerase chain reaction. Journal of Infectious Diseases, 164 (6). pp. 1075-1081. ISSN 00221899 (ISSN)

Rudalska, R., Dauch, D., Longerich, T., McJunkin, K., Wuestefeld, T., Kang, T. W., Hohmeyer, A., Pesic, M., Leibold, J., von Thun, A., Schirmacher, P., Zuber, J., Weiss, K. H., Powers, S., Malek, N.P., Eilers, M., Sipos, B., Lowe, S. W., Geffers, R., Laufer, S., Zender, L. (September 2014) In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer. Nature Medicine, 20 (10). pp. 1138-1146. ISSN 1078-8956

Ryan, D. P., Puchalski, T., Supko, J. G., Harmon, D., Maki, R., Garcia-Carbonero, R., Kuhlman, C., Winkelman, J., Merriam, P., Quigley, T., Jimeno, J., Manola, J., Demetri, G. D. (2002) A phase II and pharmacokinetic study of ecteinascidin 743 in patients with gastrointestinal stromal tumors. Oncologist, 7 (6). pp. 531-8. ISSN 1083-7159 (Print)1083-7159 (Linking)

S

Safaric Tepes, Polona, Pal, Debjani, Lindsted, Trine, Ibarra, Ingrid, Lujambio, Amaia, Jimenez Sabinina, Vilma, Senturk, Serif, Miller, Madison, Korimerla, Navya, Huang, Jiahao, Glassman, Lawrence, Lee, Paul, Zeltsman, David, Hyman, Kevin, Esposito, Michael, Hannon, Greg, Sordella, Raffaella (July 2021) An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating miR-335 expression. eLife, 10. ISSN 2050-084X

Salas-Benito, D., Melero, I., Ponz-Sarvise, M. (July 2019) Vaccination for pancreatic ductal adenocarcinoma: a hard nut to crack. Clin Cancer Res, 25 (18). pp. 5435-5437. ISSN 1078-0432 (Print)1078-0432

Schlomann, U., Koller, G., Conrad, C., Ferdous, T., Golfi, P., Garcia, A. M., Hofling, S., Parsons, M., Costa, P., Soper, R., Bossard, M., Hagemann, T., Roshani, R., Sewald, N., Ketchem, R. R., Moss, M. L., Rasmussen, F. H., Miller, M. A., Lauffenburger, D. A., Tuveson, D. A., Nimsky, C., Bartsch, J. W. (2015) ADAM8 as a drug target in pancreatic cancer. Nature Communications, 6. p. 6175. ISSN 2041-1723

Schmidt, Michael J, Naghdloo, Amin, Prabakar, Rishvanth K, Kamal, Mohamed, Cadaneanu, Radu, Garraway, Isla P, Lewis, Michael, Aparicio, Ana, Zurita-Saavedra, Amado, Corn, Paul, Kuhn, Peter, Pienta, Kenneth J, Amend, Sarah R, Hicks, James (November 2024) Polyploid cancer cells reveal signatures of chemotherapy resistance. Oncogene. ISSN 0950-9232 (Public Dataset)

Schmitt, A., Weber, S., Jatzko, A., Braus, D. F., Henn, F. A. (January 2004) Hippocampal volume and cell proliferation after acute and chronic clozapine or haloperidol treatment. J Neural Transm, 111 (1). pp. 91-100. ISSN 0300-9564 (Print)0300-9564 (Linking)

Schmitt, C. A., Fridman, J., Lowe, S. W. (July 2000) Molecular genetics of drug sensitivity and resistance in a mouse lymphoma model. British Journal of Cancer, 83. p. 4. ISSN 0007-0920

Schmitt, C. A., Lowe, S. W. (April 2001) Apoptosis is critical for drug response in vivo. Drug Resistance Updates, 4 (2). pp. 132-134. ISSN 1368-7646

Schoffski, P., Chawla, S., Maki, R. G., Italiano, A., Gelderblom, H., Choy, E., Grignani, G., Camargo, V., Bauer, S., Rha, S. Y., Blay, J. Y., Hohenberger, P., D'Adamo, D., Guo, M., Chmielowski, B., Le Cesne, A., Demetri, G. D., Patel, S. R. (April 2016) Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial. Lancet, 387 (10028). pp. 1629-37. ISSN 0140-6736

Schoffski, P., Taron, M., Jimeno, J., Grosso, F., Sanfilipio, R., Casali, P. G., Le Cesne, A., Jones, R. L., Blay, J. Y., Poveda, A., Maki, R. G., Nieto, A., Tercero, J. C., Rosell, R. (May 2011) Predictive impact of DNA repair functionality on clinical outcome of advanced sarcoma patients treated with trabectedin: a retrospective multicentric study. Eur J Cancer, 47 (7). pp. 1006-12. ISSN 1879-0852 (Electronic)0959-8049 (Linking)

Schreiber, S. L., Shamji, A. F., Clemons, P. A., Hon, C., Koehler, A. N., Munoz, B., Palmer, M., Stern, A. M., Wagner, B. K., Powers, S., Lowe, S. W., Guo, X., Krasnitz, A., Sawey, E. T., Sordella, R., Stein, L. D., Trotman, L. C., Califano, A., Dalla-Favera, R., Ferrando, A., Iavarone, A., Pasqualucci, L., Silva, J., Stockwell, B. R., Hahn, W. C., Chin, L., DePinho, R. A., Boehm, J. S., Gopal, S., Huang, A., Root, D. E., Weir, B. A., Gerhard, D. S., Zenklusen, J. C., Roth, M. G., White, M. A., Minna, J. D., MacMillan, J. B., Posner, B. A. (September 2010) Towards patient-based cancer therapeutics. Nature Biotechnology, 28 (9). pp. 904-906.

Schwartz, G. K., Tap, W. D., Qin, L. X., Livingston, M. B., Undevia, S. D., Chmielowski, B., Agulnik, M., Schuetze, S. M., Reed, D. R., Okuno, S. H., Ludwig, J. A., Keedy, V., Rietschel, P., Kraft, A. S., Adkins, D., Van Tine, B. A., Brockstein, B., Yim, V., Bitas, C., Abdullah, A., Antonescu, C. R., Condy, M., Dickson, M. A., Vasudeva, S. D., Ho, A. L., Doyle, L. A., Chen, H. X., Maki, R. G. (April 2013) Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial. Lancet Oncol, 14 (4). pp. 371-82. ISSN 1474-5488 (Electronic)1470-2045 (Linking)

Seandel, M., Shia, J., Linkov, I., Maki, R. G., Antonescu, C. R., Dupont, J. (October 2006) The activity of sunitinib against gastrointestinal stromal tumor seems to be distinct from its antiangiogenic effects. Clin Cancer Res, 12 (20 Pt ). pp. 6203-4. ISSN 1078-0432 (Print)1078-0432 (Linking)

Seidman, Andrew D, de Stanchina, Elisa, Norton, Larry, Morikawa, Aki (January 2021) Comparative Effectiveness Research Needs to Consider Optimal Dosing and Scheduling. Journal of Clinical Oncology, 39 (3). pp. 253-254. ISSN 0732-183X

Seppälä, Toni T, Zimmerman, Jacquelyn W, Sereni, Elisabetta, Plenker, Dennis, Suri, Reecha, Rozich, Noah, Blair, Alex, Thomas, Dwayne L, Teinor, Jonathan, Javed, Ammar, Patel, Hardik, Cameron, John L, Burns, William R, He, Jin, Tuveson, David A, Jaffee, Elizabeth M, Eshleman, James, Szabolcs, Annamaria, Ryan, David P, Ting, David T, Wolfgang, Christopher L, Burkhart, Richard A (September 2020) Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer. Annals of Surgery, 272 (3). pp. 427-435. ISSN 0003-4932

Seppälä, Toni T, Zimmerman, Jacquelyn W, Suri, Reecha, Zlomke, Haley, Ivey, Gabriel D, Szabolcs, Annamaria, Shubert, Christopher R, Cameron, John L, Burns, William R, Lafaro, Kelly J, He, Jin, Wolfgang, Christopher L, Zou, Ying S, Zheng, Lei, Tuveson, David A, Eshlemann, James R, Ryan, David P, Kimmelman, Alec C, Hong, Theodore S, Ting, David T, Jaffee, Elizabeth M, Burkhart, Richard A (April 2022) Precision medicine in pancreatic cancer: Patient derived organoid pharmacotyping is a predictive biomarker of clinical treatment response. Clinical Cancer Research. ISSN 1078-0432

Shakiba, Mojdeh, Zumbo, Paul, Espinosa-Carrasco, Gabriel, Menocal, Laura, Dündar, Friederike, Carson, Sandra E, Bruno, Emmanuel M, Sanchez-Rivera, Francisco J, Lowe, Scott W, Camara, Steven, Koche, Richard P, Reuter, Vincent P, Socci, Nicholas D, Whitlock, Benjamin, Tamzalit, Fella, Huse, Morgan, Hellmann, Matthew D, Wells, Daniel K, Defranoux, Nadine A, Betel, Doron, Philip, Mary, Schietinger, Andrea (February 2022) TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion. Journal of Experimental Medicine, 219 (2). ISSN 0022-1007

Sharib, Jeremy M, Creasy, John M, Wildman-Tobriner, Benjamin, Kim, Charles, Uronis, Hope, Hsu, Shiaowen David, Strickler, John H, Gholami, Sepideh, Cavnar, Michael, Merkow, Ryan P, Kingham, Peter, Kemeny, Nancy, Zani, Sabino, Jarnagin, William R, Allen, Peter J, D'Angelica, Michael I, Lidsky, Michael E (December 2022) Hepatic Artery Infusion Pumps: A Surgical Toolkit for Intraoperative Decision-Making and Management of Hepatic Artery Infusion-Specific Complications. Annals of Surgery, 276 (6). pp. 943-956. ISSN 0003-4932

Shaw, Alice T., Yeap, Beow Y., Solomon, Benjamin J., Riely, Gregory J., Gainor, Justin, Engelman, Jeffrey A., Shapiro, Geoffrey I., Costa, Daniel B., Ou, Sai-Hong I., Butaney, Mohit, Salgia, Ravi, Maki, Robert G., Varella-Garcia, Marileila, Doebele, Robert C., Bang, Yung-Jue, Kulig, Kimary, Selaru, Paulina, Tang, Yiyun, Wilner, Keith D., Kwak, Eunice L., Clark, Jeffrey W., Iafrate, A. John, Camidge, D. Ross (2011) Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. The Lancet Oncology, 12 (11). pp. 1004-1012. ISSN 1470-2045

Shen, C., Vakoc, C. R. (January 2015) Gain-of-function mutations in chromatin regulators as a tumorigenic mechanism and opportunity for therapeutic intervention. Current Opinion in Oncology, 27 (1). pp. 57-63. ISSN 1040-8746

Sherman, Mara H, Yu, Ruth T, Engle, Dannielle D, Ding, Ning, Atkins, Annette R, Tiriac, Herve, Collisson, Eric A, Connor, Frances, Van Dyke, Terry, Kozlov, Serguei, Martin, Philip, Tseng, Tiffany W, Dawson, David W, Donahue, Timothy R, Masamune, Atsushi, Shimosegawa, Tooru, Apte, Minoti V, Wilson, Jeremy S, Ng, Beverly, Lau, Sue Lynn, Gunton, Jenny E, Wahl, Geoffrey M, Hunter, Tony, Drebin, Jeffrey A, O’Dwyer, Peter J, Liddle, Christopher, Tuveson, David A, Downes, Michael, Evans, Ronald M (September 2014) Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy. Cell, 159 (1). pp. 80-93. ISSN 0092-8674

Shi, J., Vakoc, C. R. (June 2014) The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition. Molecular Cell, 54 (5). pp. 728-736. ISSN 1097-2765

Shi, J., Wang, E., Milazzo, J. P., Wang, Z., Kinney, J. B., Vakoc, C. R. (June 2015) Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains. Nat Biotechnol, 33 (6). pp. 661-67. ISSN 1546-1696 (Electronic)1087-0156 (Linking)

Shields, M. A., Maguin, P., Kumar, P., Dallas, S. L., Egeblad, M. (July 2015) Lysyl oxidases are poor therapeutic targets in pancreatic cancer. Cancer Research, 75 (Supple). A43. ISSN 0008-5472

Sindhwani, S., Syed, A.M., Ngai, J., Kingston, B.R., Maiorino, L., Rothschild, J., MacMillan, P., Zhang, Y., Rajesh, N.U., Hoang, T., Wu, J.L.Y., Wilhelm, S., Zilman, A., Gadde, S., Sulaiman, A., Ouyang, B., Lin, Z., Wang, L., Egeblad, M., Chan, W.C.W. (January 2020) The entry of nanoparticles into solid tumours. Nat Mater. ISSN 1476-1122 (Public Dataset)

Singer, S., Socci, N. D., Ambrosini, G., Sambol, E., Decarolis, P., Wu, Y., O'Connor, R., Maki, R., Viale, A., Sander, C., Schwartz, G. K., Antonescu, C. R. (July 2007) Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma. Cancer Res, 67 (14). pp. 6626-36. ISSN 0008-5472 (Print)0008-5472 (Linking)

Smith, Joan C, Sheltzer, Jason M (March 2022) Genome-wide identification and analysis of prognostic features in human cancers. Cell Reports, 38 (13). p. 110569. ISSN 2211-1247

Smolen, G. A., Sordella, R., Muir, B., Mohapatra, G., Barmettler, A., Archibald, H., Kim, W. J., Okimoto, R. A., Bell, D. W., Sgroi, D. C., Christensen, J. G., Settleman, J., Haber, D. A. (February 2006) Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proceedings of the National Academy of Sciences of the United States of America, 103 (7). pp. 2316-21. ISSN 0027-8424

Soengas, M. S., Lowe, S. W. (May 2003) Apoptosis and melanoma chemoresistance. Oncogene, 22 (20). pp. 3138-3151. ISSN 0950-9232

Somlo, George, Barlow, William, Moore, Halle, Gralow, Julie, Schott, Anne, Hayes, Daniel, Kuhn, Peter, Hicks, James, Lew, Danika, Tripathy, Debu, Hortobagyl, Gabriel (May 2015) Fulvestrant alone versus fulvestrant and everolimus versus fulvestrant, everolimus and anastrozole: A Phase III randomized, placebo-controlled trial in postmenopausal patients with hormone-receptor-positive stage IV breast cancer: SWOG-Clinical Trials Ini. Cancer Research, 75 (9 Supp). OT2-1. ISSN 1538-7445

Sordella, R., Bell, D. W., Haber, D. A., Settleman, J. (August 2004) Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science, 305 (5687). pp. 1163-7. ISSN 1095-9203 (Electronic)

Standring, Oliver, Gholami, Sepideh (September 2023) Adjuvant hepatic artery infusion pump chemotherapy for resected colorectal cancer liver metastases. Surgery, 174 (3). pp. 747-749. ISSN 0039-6060

Stewart, D., Stillman, B. (2005) Molecular Approaches to Controlling Cancer. In: Cold Spring Harbor Symposia on Quantitative Biology LXX: Molecular Approaches to Controlling Cancer, Cold Spring Harbor.

Svingen, P. A., Loegering, D., Rodriquez, J., Meng, X. W., Mesner, P. W., Holbeck, S., Monks, A., Krajewski, S., Scudiero, D. A., Sausville, E. A., Reed, J. C., Lazebnik, Y. A., Kaufmann, S. H. (October 2004) Components of the cell death machine and drug sensitivity of the National Cancer Institute cell line panel. Clinical Cancer Research, 10 (20). pp. 6807-6820. ISSN 1078-0432

T

Takao, Sumiko, Forbes, Lauren, Uni, Masahiro, Cheng, Shuyuan, Pineda, Jose Mario Bello, Tarumoto, Yusuke, Cifani, Paolo, Minuesa, Gerard, Chen, Celine, Kharas, Michael G, Bradley, Robert K, Vakoc, Christopher R, Koche, Richard P, Kentsis, Alex (February 2021) Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia. eLife, 10. pp. 1-46. ISSN 2050-084X

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschenes, A., Somerville, T., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., LaComb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. A., Johnson, M., Arora, K., Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E. D., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P. J., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., DiMaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O'Kane, G. M., Notta, F., Kim, E. J., Crawford, J. M., Devoe, C. E., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R. A., Knox, J. J., Krasnitz, A., Gallinger, S., Tuveson, D. A. (May 2018) Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discovery, 8 (9). pp. 1112-1129. ISSN 21598274 (Public Dataset)

Tiriac, H., Plenker, D., Baker, L. A., Tuveson, D. A. (March 2019) Organoid models for translational pancreatic cancer research. Curr Opin Genet Dev, 54. pp. 7-11. ISSN 0959-437x

Troesch, A., Nguyen, H., Miyada, C. G., Desvarenne, S., Gingeras, T. R., Kaplan, P. M., Cros, P., Mabilat, C. (1999) Mycobacterium species identification and rifampin resistance testing with high-density DNA probe arrays. Journal of Clinical Microbiology, 37 (1). pp. 49-55. ISSN 00951137 (ISSN)

Tse, A. N., Klimstra, D. S., Gonen, M., Shah, M., Sheikh, T., Sikorski, R., Carvajal, R., Mui, J., Tipian, C., O'Reilly, E., Chung, K., Maki, R., Lefkowitz, R., Brown, K., Manova-Todorova, K., Wu, N., Egorin, M. J., Kelsen, D., Schwartz, G. K. (October 2008) A phase 1 dose-escalation study of irinotecan in combination with 17-allylamino-17-demethoxygeldanamycin in patients with solid tumors. Clin Cancer Res, 14 (20). pp. 6704-11. ISSN 1078-0432 (Print)1078-0432 (Linking)

Tully, T. (September 2004) From genes to drugs for cognitive dysfunction. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 130B (1). p. 3. ISSN 0148-7299

Tuveson, D., Clevers, H. (June 2019) Cancer modeling meets human organoid technology. Science, 364 (6444). pp. 952-955. ISSN 0036-8075

Tuveson, David A (April 2021) Fighting the Sixth Decade of the Cancer War with Better Cancer Models. Cancer Discovery, 11 (4). pp. 801-804. ISSN 2159-8274

U

Urick, A. K., Hawk, L. M., Cassel, M. K., Mishra, N. K., Liu, S., Adhikari, N., Zhang, W., Dos Santos, C. O., Hall, J. L., Pomerantz, W. C. (October 2015) Dual Screening of BPTF and Brd4 Using Protein-Observed Fluorine NMR Uncovers New Bromodomain Probe Molecules. ACS Chem Biol, 10 (10). pp. 2246-56. ISSN 1554-8937 (Electronic)1554-8929 (Linking)

V

Vakoc, C. (January 2018) Cancer drug target identification using domain-focused CRISPR screening. Clinical Cancer Research, 24 (2 Supp). p. 19. ISSN 1078-0432

Vakoc, C. R., Garcia-Manero, G., Look, A. T. (April 2014) Cancer therapy resistance: chasing epigenetics. Nature Medicine, 20 (4). pp. 340-341. ISSN 1078-8956

Vareslija, D., McBryan, J., Fagan, A., Redmond, A., Hao, Y., Hill, A. D. K., Young, L. S. (May 2015) Adaptation to AI therapy in breast cancer can induce dynamic alterations in ER activity resulting in estrogen independent metastatic tumours. Cancer Research, 75 (9 supp). Abstract nr P3-05. ISSN 0008-5472

Verspoor, F. G. M., Mastboom, M. J. L., Hannink, G., Maki, R. G., Wagner, A., Bompas, E., Desai, J., Italiano, A., Seddon, B. M., van der Graaf, W. T. A., Blay, J. Y., Brahmi, M., Eberst, L., Stacchiotti, S., Mir, O., van de Sande, M. A. J., Gelderblom, H., Cassier, P. A. (October 2019) Long-term efficacy of imatinib mesylate in patients with advanced Tenosynovial Giant Cell Tumor. Sci Rep, 9 (1). p. 14551. ISSN 2045-2322

Vickman, Renee E, Faget, Douglas V, Beachy, Philip, Beebe, David, Bhowmick, Neil A, Cukierman, Edna, Deng, Wu-Min, Granneman, James G, Hildesheim, Jeffrey, Kalluri, Raghu, Lau, Ken S, Lengyel, Ernst, Lundeberg, Joakim, Moscat, Jorge, Nelson, Peter S, Pietras, Kristian, Politi, Katerina, Puré, Ellen, Scherz-Shouval, Ruth, Sherman, Mara H, Tuveson, David, Weeraratna, Ashani T, White, Richard M, Wong, Melissa H, Woodhouse, Elisa C, Zheng, Ying, Hayward, Simon W, Stewart, Sheila A (October 2020) Deconstructing tumor heterogeneity: the stromal perspective. Oncotarget, 11 (40). pp. 3621-3632. ISSN 1949-2553

W

Wagner, A. J., Malinowska-Kolodziej, I., Morgan, J. A., Qin, W., Fletcher, C. D., Vena, N., Ligon, A. H., Antonescu, C. R., Ramaiya, N. H., Demetri, G. D., Kwiatkowski, D. J., Maki, R. G. (February 2010) Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors. J Clin Oncol, 28 (5). pp. 835-40. ISSN 1527-7755 (Electronic)0732-183X (Linking)

Wang, Zhikai, Moresco, Philip, Yan, Ran, Li, Jiayun, Gao, Ya, Biasci, Daniele, Yao, Min, Pearson, Jordan, Hechtman, Jaclyn F, Janowitz, Tobias, Zaidi, Raza M, Weiss, Matthew J, Fearon, Douglas T (January 2022) Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack. Proceedings of the National Academy of Sciences of USA, 119 (4). e2119463119-e2119463119. ISSN 0027-8424

Wang, Zhikai, Yan, Ran, Li, Jiayun, Gao, Ya, Moresco, Philip, Yao, Min, Hechtman, Jaclyn F, Weiss, Matthew J, Janowitz, Tobias, Fearon, Douglas T (September 2020) Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy. bioRxiv. (Unpublished)

Wang, Zihua, Sew, Pui-Hoon, Ambrose, Helen, Ryan, Stephen, Chong, Samuel S, Lee, Edmund JD, Lee, Caroline GL (December 2006) Nucleotide sequence analyses of the MRP 1 gene in four populations suggest negative selection on its coding region. BMC Genomics, 7 (1). ISSN 1471-2164

Wendel, H. G., De Stanchina, E., Fridman, J. S., Malina, A., Ray, S., Kogan, S., Cordon-Cardo, C., Pelletier, J., Lowe, S. W. (March 2004) Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature, 428 (6980). pp. 332-7. ISSN 1476-4687 (Electronic)

Wendel, H. G., Lowe, S. W. (July 2004) Reversing drug resistance in vivo. Cell Cycle, 3 (7). pp. 847-9. ISSN 1551-4005 (Electronic)

Wendel, H. G., Malina, A., Zhao, Z., Zender, L., Kogan, S. C., Cordon-Cardo, C., Pelletier, J., Lowe, S. W. (August 2006) Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. Cancer Res, 66 (15). pp. 7639-46. ISSN 0008-5472 (Print)

Wendel, Hans-Guido, de Stanchina, Elisa, Cepero, Enriqué, Ray, Sagarika, Emig, Michael, Fridman, Jordan S., Veach, Darren R., Bornmann, William G., Clarkson, Bayard, McCombie, W. Richard, Kogan, Scott C., Hochhaus, Andreas, Lowe, Scott W. (May 2006) Loss of p53 impedes the antileukemic response to BCR-ABL inhibition. Proceedings of the National Academy of Sciences of the United States of America, 103 (19). pp. 7444-9. ISSN 0027-8424

Wiede, Florian, Lu, Kun-Hui, Du, Xin, Zeissig, Mara N, Xu, Rachel, Goh, Pei Kee, Xirouchaki, Chrysovalantou E, Hogarth, Samuel J, Greatorex, Spencer, Sek, Kevin, Daly, Roger J, Beavis, Paul A, Darcy, Phillip K, Tonks, Nicholas K, Tiganis, Tony (November 2021) PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity. Cancer Discovery. ISSN 2159-8274

Wojnarowicz, Paulina M, Escolano, Marta Garcia, Huang, Yun-Han, Desai, Bina, Chin, Yvette, Shah, Riddhi, Xu, Sijia, Yadav, Saurabh, Yaklichkin, Sergey, Ouerfelli, Ouathek, Soni, Rajesh Kumar, Philip, John, Montrose, David C, Healey, John H, Rajasekhar, Vinagolu K, Garland, William A, Ratiu, Jeremy, Zhuang, Yuan, Norton, Larry, Rosen, Neal, Hendrickson, Ronald C, Zhou, Xi Kathy, Iavarone, Antonio, Massague, Joan, Dannenberg, Andrew J, Lasorella, Anna, Benezra, Robert (May 2021) Anti-tumor effects of an ID antagonist with no observed acquired resistance. npj Breast Cancer, 7 (1). p. 58. ISSN 2374-4677

Wolff, R. A., Wang-Gillam, A., Alvarez, H., Tiriac, H., Engle, D., Hou, S., Groff, A. F., Lucas, A. S., Bernard, V., Allenson, K., Castillo, J., Kim, D., Mulu, F., Huang, J., Stephens, B., Wistuba, I. I., Katz, M., Varadhachary, G., Park, Y., Hicks, J., Chinnaiyan, A., Scampavia, L., Spicer, T., Gerhardinger, C., Maitra, A., Tuveson, D., Rinn, J., Lizee, G., Yee, C., Levine, A. J. (March 2018) Dynamic changes during the treatment of pancreatic cancer. Oncotarget, 9 (19). pp. 14764-14790. ISSN 1949-2553

Wong, Willard, Brogi, Edi, Reis-Filho, Jorge S, Plitas, George, Robson, Mark, Norton, Larry, Morrow, Monica, Wen, Hannah Y (July 2021) Poor response to neoadjuvant chemotherapy in metaplastic breast carcinoma. npj Breast Cancer, 7 (1). p. 96. ISSN 2374-4677

X

Xie, Y. Y., Cao, Z., Wong, W. P., Guan, Y. X., Zhang, J., Walczak, E., Murphy, D., Ran, L., Sirota, I., Wang, S. Q., Shukla, S., Gao, D., Wongvipat, J., Knott, S., Chang, K., Antonescu, C., Hannon, G., Chi, P., Chen, Y. (January 2018) COP1-ETS axis regulates ERK transcriptional output and modulates sensitivity to MAPK inhibitors. Clinical Cancer Research, 24 (2 Supp). p. 61. ISSN 1078-0432

Y

Yao, Z., Fenoglio, S., Gao, D. C., Camiolo, M., Stiles, B., Lindsted, T., Schlederer, M., Johns, C., Altorki, N., Mittal, V., Kenner, L., Sordella, R. (August 2010) TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proceedings of the National Academy of Sciences of the United States of America, 107 (35). pp. 15535-40. ISSN 0027-8424

Yilancioglu, K., Weinstein, Z. B., Meydan, C., Akhmetov, A., Toprak, I., Durmaz, A., Iossifov, I., Kazan, H., Roth, F. P., Cokol, M. (August 2014) Target-independent prediction of drug synergies using only drug lipophilicity. Journal of Chemical Information and Modeling, 54 (8). pp. 2286-2293. ISSN 15499596

Yohe, M. E., Heske, C. M., Stewart, E., Adamson, P. C., Ahmed, N., Antonescu, C. R., Chen, E., Collins, N., Ehrlich, A., Galindo, R. L., Gryder, B. E., Hahn, H., Hammond, S., Hatley, M. E., Hawkins, D. S., Hayes, M. N., Hayes-Jordan, A., Helman, L. J., Hettmer, S., Ignatius, M. S., Keller, C., Khan, J., Kirsch, D. G., Linardic, C. M., Lupo, P. J., Rota, R., Shern, J. F., Shipley, J., Sindiri, S., Tapscott, S. J., Vakoc, C. R., Wexler, L. H., Langenau, D. M. (June 2019) Insights into pediatric rhabdomyosarcoma research: Challenges and goals. Pediatr Blood Cancer, 66 (10). article no. e27869. ISSN 1545-5009

Yu, C. C., Wortman, J. C., He, T. F., Solomon, S., Zhang, R. Z., Rosario, A., Wang, R., Tu, T., Schmolze, D., Yuan, Y., Yost, S. E., Li, X., Levine, H., Atwal, G., Lee, P. P. (November 2020) Physics Approaches to the Spatial Distribution of Immune Cells in Tumors. Rep Prog Phys. ISSN 0034-4885

Z

Zender, L., Spector, M. S., Xue, W., Flemming, P., Mu, D., Cordon-Cardo, C., Powers, S., Hannon, G. J., Lucito, R., Lowe, S. W. (October 2005) Representational oligonucleotide microarray (ROMA) identifies cIAP1/cIAP2 as candidate oncogenes in mouse and human hepatocarcinogenesis-validation of cIAP1 as a therapeutic target in liver cancer in a new mouse model of hepatocellular carcinoma. Hepatology, 42 (4). 244A-244A. ISSN 0270-9139

Zheng, W., Johnston, S. A., Joshua-Tor, L. (April 1998) The unusual active site of Gal6/bleomycin hydrolase can act as a carboxypeptidase, aminopeptidase, and peptide ligase. Cell, 93 (1). pp. 103-9. ISSN 0092-8674 (Print)0092-8674 (Linking) (Public Dataset)

Zuber, J., Radtke, I., Pardee, T. S., Zhao, Z., Rappaport, A. R., Luo, W., McCurrach, M. E., Yang, M. M., Dolan, M. E., Kogan, S. C., Downing, J. R., Lowe, S. W. (April 2009) Mouse models of human AML accurately predict chemotherapy response. Genes Dev, 23 (7). pp. 877-89.

This list was generated on Sun Dec 22 20:49:45 2024 EST.