Additional materials of the author at
CSHL Institutional Repository

Stillman, Bruce (2024) Establishing a biochemical understanding of the initiation of chromosome replication in bacteria. Proceedings of the National Academy of Sciences of the United States of America, 121(23) pp. e2400667121.

Hu, Yixin , Stillman, Bruce (2023) Origins of DNA replication in eukaryotes. Molecular Cell, pp. S1097-2765(22)01203.

Sheu, Yi-Jun, Kawaguchi, Risa Karakida, Gillis, Jesse , Stillman, Bruce (2022) Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters. eLife, 11 pp. e84320.

Stillman, Bruce (2022) The remarkable gymnastics of ORC.. eLife, 11

Feng, Xiang, Noguchi, Yasunori, Barbon, Marta, Stillman, Bruce, Speck, Christian , Li, Huilin (2021) The structure of ORC–Cdc6 on an origin DNA reveals the mechanism of ORC activation by the replication initiator Cdc6. Nature Communications, 12(1)

Sheu, Yi-Jun, Kawaguchi, Risa Karakida, Gillis, Jesse , Stillman, Bruce (2021) Prevalent and Dynamic Binding of the Cell Cycle Checkpoint Kinase Rad53 to Gene Promoters. bioRxiv,

Hossain, Manzar, Bhalla, Kuhulika , Stillman, Bruce (2021) Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication. Molecular Cell,

Chou, Hsiang-Chen, Bhalla, Kuhulika, Demerdesh, Osama El, Klingbeil, Olaf, Hanington, Kaarina, Aganezov, Sergey, Andrews, Peter, Alsudani, Habeeb, Chang, Kenneth, Vakoc, Christopher R, Schatz, Michael C, McCombie, W Richard , Stillman, Bruce (2021) The human Origin Recognition Complex is essential for pre-RC assembly, mitosis and maintenance of nuclear structure.. eLife, 10

Hu, Y, Tareen, A., Sheu, Y. J., Ireland, W. T., Speck, C., Li, H., Joshua-Tor, L., Kinney, J. B. , Stillman, B. (2020) Evolution of DNA replication origin specification and gene silencing mechanisms. Nature Communications, 11(1) pp. 5175.

Jaremko, M. J., On, K. F., Thomas, D. R., Stillman, B. , Joshua-Tor, L. (2020) The dynamic nature of the human origin recognition complex revealed through five cryoEM structures. Elife, 9 pp. e58622.

Chou, H. C., Bhalla, K., El Demerdash, O., Klingbeil, O., Hanington, Kaarina, Aganezov, S., Andrews, P., Alsudani, H., Chang, K., Vakoc, C. R., Schatz, M. C., McCombie, W. R. , Stillman, B. (2020) The human Origin Recognition Complex is essential for pre-RC assembly, mitosis and maintenance of nuclear structure. BioRxiv,

Yuan, Zuanning, Schneider, Sarah, Dodd, Thomas, Riera, A., Bai, Lin, Yan, Chunli, Magdalou, Indiana, Ivanov, Ivaylo, Stillman, Bruce, Li, Huilin , Speck, C. (2020) Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6. Proceedings of the National Academy of Sciences of the United States of America, 117(30) pp. 17747-17756.

Hu, Y, Tareen, A, Sheu, Y-J, Ireland, WT, Speck, C, Li, H, Joshua-Tor, L, Kinney, JB , Stillman, B (2020) Evolution of DNA Replication Origin Specification and Gene Silencing Mechanisms. BioRxiv,

Greider, Carol W, Sheltzer, Jason M, Cantalupo, Nancy C, Copeland, Wilbert B, Dasgupta, Nilanjana, Hopkins, Nancy, Jansen, Jaclyn M, Joshua-Tor, Leemor, McDowell, Gary S, Metcalf, Jessica L, McLaughlin, BethAnn, Olivarius, Ann, O'Shea, Erin K, Raymond, Jennifer L, Ruebain, David, Steitz, Joan A, Stillman, Bruce, Tilghman, Shirley M, Valian, Virginia, Villa-Komaroff, Lydia , Wong, Joyce Y (2019) Increasing gender diversity in the STEM research workforce.. Science, 366(6466) pp. 692-695. American Association for the Advancement of Science (AAAS).

Dunn, A., Johnstone, R. W. , Stillman, B. (2019) Joseph F. Sambrook (1939-2019). Nat Struct Mol Biol, 26(10) pp. 846-847.

Hossain, Manzar, Bhalla, Kuhulika , Stillman, Bruce (2019) Cyclin binding Cy motifs have multiple activities in the initiation of DNA replication. bioRxiv,

On, Kin Fan, Jaremko, Matt, Stillman, Bruce , Joshua-Tor, Leemor (2018) A structural view of the initiators for chromosome replication. Current Opinion in Structural Biology, 53 pp. 131-139.

Stillman, Bruce (2018) Histone Modifications: Insights into Their Influence on Gene Expression. Cell,

Tramentozzi, E., Ferraro, P., Hossain, M., Stillman, B., Bianchi, V. , Pontarin, G. (2018) The dNTP triphosphohydrolase activity of SAMHD1 persists during S-phase when the enzyme is phosphorylated at T592. Cell Cycle, 17(9) pp. 1102-1114.

Stillman, Bruce (2018) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Noguchi, Y., Yuan, Z., Bai, L., Schneider, S., Zhao, G., Stillman, B., Speck, C. , Li, H. (2017) Cryo-EM structure of Mcm2-7 double hexamer on DNA suggests a lagging-strand DNA extrusion model. Proc Natl Acad Sci U S A, 114(45) pp. E9529-9538.

Yuan, Z., Riera, A., Bai, L., Sun, J., Nandi, S., Spanos, C., Chen, Z. A., Barbon, M., Rappsilber, J., Stillman, B., Speck, C. , Li, H. (2017) Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1. Nat Struct Mol Biol, 24(3) pp. 316-324.

Tocilj, A., On, K. F., Yuan, Z., Sun, J., Elkayam, E., Li, H., Stillman, B. , Joshua-Tor, L. (2017) Structure of the active form of human Origin Recognition Complex and its ATPase motor module. Elife, 6

Stillman, Bruce (2017) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Speck, C., Riera, A., Yuan, Z., Sun, J., Barbon, M., Rappsilber, J., Stillman, B. , Li, H. (2016) Key mechanism in the loading and activation of the replicative helicase MCM2-7. Febs Journal, 283 pp. 12-12.

Hossain, M. , Stillman, B. (2016) Opposing roles for DNA replication initiator proteins ORC1 and CDC6 in control of Cyclin E gene transcription. Elife, 5

MacDiarmid, J. A., Langova, V., Bailey, D., Pattison, S. T., Pattison, S. L., Christensen, N., Armstrong, L. R., Brahmbhatt, V. N., Smolarczyk, K., Harrison, M. T., Costa, M., Mugridge, N. B., Sedliarou, I., Grimes, N. A., Kiss, D. L., Stillman, B., Hann, C. L., Gallia, G. L., Graham, R. M. , Brahmbhatt, H. (2016) Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model. PLoS One, 11(4) pp. e0151832.

Sheu, Y. J., Kinney, J. B. , Stillman, B. (2016) Concerted activities of Mcm4, Sld3 and Dbf4 in control of origin activation and DNA replication fork progression. Genome Res, 26(3) pp. 315-330.

Stillman, Bruce (2016) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Stillman, B. (2015) Reconsidering DNA Polymerases at the Replication Fork in Eukaryotes. Molecular Cell, 59(2) pp. 139-141.

Kara, N., Hossain, M., Prasanth, S. G. , Stillman, B. (2015) Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning During G1 Phase and Assembly of the Origin Recognition Complex in Human Cells. J Biol Chem, 290(19) pp. 12355-12369.

Stillman, Bruce (2015) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Hettmer, S., Li, Z., Billin, A. N., Barr, F. G., Cornelison, D. D., Ehrlich, A. R., Guttridge, D. C., Hayes-Jordan, A., Helman, L. J., Houghton, P. J., Khan, J., Langenau, D. M., Linardic, C. M., Pal, R., Partridge, T. A., Pavlath, G. K., Rota, R., Schafer, B. W., Shipley, J., Stillman, B., Wexler, L. H., Wagers, A. J. , Keller, C. (2014) Rhabdomyosarcoma: Current Challenges and Their Implications for Developing Therapies. Cold Spring Harbor Perspectives in Medicine, 4(11)

Sun, J., Fernandez-Cid, A., Riera, A., Tognetti, S., Yuan, Z., Stillman, B., Speck, C. , Li, H. (2014) Structural and mechanistic insights into Mcm2-7 double-hexamer assembly and function. Genes & Development, 28(20) pp. 2291-303.

Mazurek, A., Park, Y., Miething, C., Wilkinson, J. E., Gillis, J., Lowe, S. W, Vakoc, C. R , Stillman, B. (2014) Acquired Dependence of Acute Myeloid Leukemia on the DEAD-Box RNA Helicase DDX5. Cell Reports, 7(6) pp. 1887-1899.

Sheu, Y. J., Kinney, J. B., Lengronne, A., Pasero, P. , Stillman, B. (2014) Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression. Proceedings of the National Academy of Sciences of the United States of America, 111(18) pp. E1899-1908.

Stillman, B., Speck, C. , Li, H. L. (2014) Biochemical studies on replication of the genome in eukaryotes. Faseb Journal, 28(1)

Stillman, Bruce (2014) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Stillman, B. (2013) Deoxynucleoside triphosphate (dNTP) synthesis and destruction regulate the replication of both cell and virus genomes. Proceedings of the National Academy of Sciences of the United States of America, 110(35) pp. 14120-14121.

Sun, J., Evrin, C., Samel, S. A., Fernandez-Cid, A., Riera, A., Kawakami, H., Stillman, B., Speck, C. , Li, H. (2013) Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA. Nature Structural and Molecular Biology, 20(8) pp. 944-951.

Rossmann, M. P. , Stillman, B. (2013) Immunoblotting histones from yeast whole-cell protein extracts. Cold Spring Harbor Protocols, 2013(7)

O'Donnell, M., Langston, L. , Stillman, B. (2013) Principles and concepts of DNA replication in bacteria, archaea, and eukarya. Cold Spring Harbor Perspectives in Biology, 5(7)

Stillman, Bruce (2013) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Kawakami, H. , Stillman, B. (2012) In vitro reconstitution of budding yeast pre-RC, competent in recruitment of recombinant pre-IC components, using purified, recombinant proteins. Genes & Genetic Systems, 87(6) pp. 385-385.

Hossain, M. , Stillman, B. (2012) Meier-Gorlin syndrome mutations disrupt an Orc1 CDK inhibitory domain and cause centrosome reduplication. Genes and Development, 26(16) pp. 1797-810.

Gineau, L., Cognet, C., Kara, N., Lach, F. P., Dunne, J., Veturi, U., Picard, C., Trouillet, C., Eidenschenk, C., Aoufouchi, S., Alcaïs, A., Smith, O., Geissmann, F., Feighery, C., Abel, L., Smogorzewska, A., Stillman, B., Vivier, E., Casanova, J. L. , Jouanguy, E. (2012) Partial MCM4 deficiency in patients with growth retardation, adrenal insufficiency, and natural killer cell deficiency. Journal of Clinical Investigation, 122(3) pp. 821-832.

Sun, J., Kawakami, H., Zech, J., Speck, C., Stillman, B. , Li, H. (2012) Cdc6-Induced Conformational Changes in ORC Bound to Origin DNA Revealed by Cryo-Electron Microscopy. Structure, 20(3) pp. 534-544.

Mazurek, A., Luo, W., Krasnitz, A., Hicks, J., Powers, R. S. , Stillman, B. (2012) DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells. Cancer Discovery, 2(9) pp. 812-825.

Stillman, B., Grodzicker, T., Martienssen, R. , Stewart, D. (2012) The Biology of Plants. Stillman, Bruce, Grodzicker, Terri, Martienssen, Rob , Stewart, David (Ed.). Cold Spring Harbor Symposia on Quantitative Biology, 77

Stillman, Bruce (2012) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Kang, B., Pu, M., Hu, G., Wen, W., Dong, Z., Zhao, K., Stillman, B. , Zhang, Z. (2011) Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly. Genes and Development, 25(13) pp. 1359-1364.

McJunkin, K., Mazurek, A., Premsrirut, P. K., Zuber, J., Dow, L. E., Simon, J., Stillman, B. , Lowe, S. W. (2011) Reversible suppression of an essential gene in adult mice using transgenic RNA interference. Proceedings of the National Academy of Sciences of the United States of America, 108(17) pp. 7113-7118.

Rossmann, M. P., Luo, W., Tsaponina, O., Chabes, A. , Stillman, B. (2011) A Common Telomeric Gene Silencing Assay Is Affected by Nucleotide Metabolism. Molecular Cell, 42(1) pp. 127-136.

Hoek, M., Myers, M. P. , Stillman, B. (2011) An analysis of CAF-1 interacting proteins reveals dynamic and direct interactions with the ku complex and 14-3-3 proteins . Journal of Biological Chemistry, 286(12) pp. 10876-10887.

Nakano, S., Stillman, B. , Horvitz, H. R. (2011) Replication-coupled chromatin assembly generates a neuronal bilateral asymmetry in C. elegans. Cell, 147(7) pp. 1525-1536.

Stillman, Bruce (2011) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Prasanth, S. G., Shen, Z., Prasanth, K. V. , Stillman, B. (2010) Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization. Proceedings of the National Academy of Sciences of the United States of America, 107(34) pp. 15093-8.

Sheu, Y. J. , Stillman, B. (2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature, 463(7277) pp. 113-117.

Lydeard, J. R., Lipkin-Moore, Z., Sheu, Y. J., Stillman, B., Burgers, P. M. , Haber, J. E. (2010) Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes and Development, 24(11) pp. 1133-1144.

Mok, J., Kim, P. M., Lam, H. Y. K., Piccirillo, S., Zhou, X., Jeschke, G. R., Sheridan, D. L., Parker, S. A., Desai, V., Jwa, M., Cameroni, E., Niu, H., Good, M., Remenyi, A., Ma, J. L. N., Sheu, Y. J., Sassi, H. E., Sopko, R., Chan, C. S. M., De Virgilio, C., Hollingsworth, N. M., Lim, W. A., Stern, D. F., Stillman, B., Andrews, B. J., Gerstein, M. B., Snyder, M. , Turk, B. E. (2010) Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Science Signaling, 3(109)

Stillman, Bruce (2010) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Evrin, C., Clarke, P., Zech, J., Lurz, R., Sun, J. C., Uhle, S., Li, H. L., Stillman, B. , Speck, C. (2009) A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication. Proceedings of the National Academy of Sciences of the United States of America, 106(48) pp. 20240-20245.

Li, Q., Fazly, A. M., Zhou, H., Huang, S., Zhang, Z. , Stillman, B. (2009) The elongator complex interacts with PCNA and modulates transcriptional silencing and sensitivity to DNA damage agents. Plos Genetics, 5(10) pp. e1000684.

MacDiarmid, J. A., Amaro-Mugridge, N. B., Madrid-Weiss, J., Sedliarou, I., Wetzel, S., Kochar, K., Brahmbhatt, V. N., Phillips, L., Pattison, S. T., Petti, C., Stillman, B., Graham, R. M. , Brahmbhatt, H. (2009) Sequential treatment of drug-resistant tumors with targeted minicells containing siRNA or a cytotoxic drug. Nature Biotechnology, 27(7) pp. 643-651.

Bohland, J. W., Wu, C., Barbas, H., Bokil, H., Bota, M., Breiter, H. C., Cline, H. T., Doyle, J. C., Freed, P. J., Greenspan, R. J., Haber, S. N., Hawrylycz, M., Herrera, D. G., Hilgetag, C. C., Huang, Z. J., Jones, A., Jones, E. G., Karten, H. J., Kleinfeld, D., Kotter, R., Lester, H. A., Lin, J. M., Mensh, B. D., Mikula, S., Panksepp, J., Price, J. L., Safdieh, J., Saper, C. B., Schiff, N. D., Schmahmann, J. D., Stillman, B. W., Svoboda, K., Swanson, L. W., Toga, A. W., Van Essen, D. C., Watson, J. D. , Mitra, P. P. (2009) A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale. PLoS Computational Biology, 5(3) pp. e1000334.

Hemerly, A. S., Prasanth, S. G., Siddiqui, K. , Stillman, B. (2009) Orc1 Controls Centriole and Centrosome Copy Number in Human Cells. Science, 323(5915) pp. 789-793.

Bohland, Jason W, Wu, Caizhi, Barbas, Helen, Bokil, Hemant, Bota, Mihail, Breiter, Hans C, Cline, Hollis T, Doyle, John C, Freed, Peter J, Greenspan, Ralph J, Haber, Suzanne N, Hawrylycz, Michael, Herrera, Daniel G, Hilgetag, Claus C, Huang, Z Josh, Jones, Allan, Jones, Edward G, Karten, Harvey J, Kleinfeld, David, Kotter, Rolf, Lester, Henry A, Lin, John M, Mensh, Brett D, Mikula, Shawn, Panksepp, Jaak, Price, Joseph L, Safdieh, Joseph, Saper, Clifford B, Schiff, Nicholas D, Schmahmann, Jeremy D, Stillman, Bruce W, Svoboda, Karel, Swanson, Larry W, Toga, Arthur W, Essen, David C Van, Watson, James D , Mitra, Partha P (2009) A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale. PLoS Computational Biology,

Yu, S. R., Smirnova, J. B., Friedberg, E. C., Stillman, B., Akiyama, M., Owen-Hughes, T., Waters, R. , Reed, S. H. (2009) ABF1-binding Sites Promote Efficient Global Genome Nucleotide Excision Repair. Journal of Biological Chemistry, 284(2) pp. 966-973.

Stillman, Bruce (2009) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Chen, Z. Q., Speck, C., Wendel, P., Tang, C. Y., Stillman, B. , Lill, H. L. (2008) The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 105(30) pp. 10326-10331.

Stillman, B. (2008) DNA polymerases at the replication fork in eukaryotes. Molecular Cell, 30(3) pp. 259-60.

Fuller, R. S., Bambara, R. A., Baker, T., Funnell, B., Wahle, E., O'Donnell, M., Kaiser, D., Skarstad, K., Konforti, B., Maki, S., Katayama, T., Sekimizu, K., Weiner, J. H., Davis, R. W., Rowen, L., Goodman, M. F., Spudich, J., Pfeffer, S., Richardson, C. C., Polaczek, P., Calendar, R., Kolodner, R., Griffith, J., Stillman, B., Modrich, P., Brenner, C. , Yanofsky, C. (2008) A tribute to Arthur Kornberg 1918-2007. Nature Structural & Molecular Biology, 15(1) pp. 2-17.

Stillman, Bruce (2008) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Siddiqui, K. , Stillman, B. (2007) ATP dependent assembly of the human origin recognition complex. Journal of Biological Chemistry, 282(44) pp. 32370-32383.

Speck, C. , Stillman, B. (2007) Initiation of DNA replication - Assembly of a molecular machine depends on origin DNA. Febs Journal, 274(S1) pp. 72-72.

MacDiarmid, J. A., Mugridge, N. B., Weiss, J. C., Phillips, L., Burn, A. L., Paulin, R. P., Haasdyk, J. E., Dickson, K. A., Brahmbhatt, V. N., Pattison, S. T., James, A. C., Al Bakri, G., Straw, R. C., Stillman, B., Graham, R. M. , Brahmbhatt, H. (2007) Bacterially derived 400 nm particles for encapsulation and cancer cell targeting of chemotherapeutics. Cancer Cell, 11(5) pp. 431-445.

Speck, C. , Stillman, B. (2007) Cdc6 ATPase activity regulates ORC center dot Cdc6 stability and the selection of specific DNA sequences as origins of DNA replication. Journal of Biological Chemistry, 282(16) pp. 11705-11714.

Chabes, A. , Stillman, B. (2007) Constitutively high dNTP concentration inhibits cell cycle progression and the DNA damage checkpoint in yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 104(4) pp. 1183-1188.

Stillman, Bruce (2007) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Sheu, Y. J. , Stillman, B. (2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell, 24(1) pp. 101-13.

Stillman, B. , Stewart, D. (2006) Regulatory RNAs. Stillman, Bruce , Stewart, David (Ed.). Cold Spring Harbor Symposia on Quantitative Biology. Cold Spring Harb Symp Quant Biol, 71 Woodbury, NY:

Stillman, Bruce (2006) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Varmus, H. , Stillman, B. (2005) Support for the Human Cancer Genome Project. Science, 310(5754) pp. 1615-1615.

Speck, C., Chen, Z., Li, H. , Stillman, B. (2005) ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA. Nat Struct Mol Biol, 12(11) pp. 965-71.

Hsu, H. C., Stillman, B. , Xu, R. M. (2005) Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing. Proc Natl Acad Sci U S A, 102(24) pp. 8519-24.

Stillman, B. (2005) Origin recognition and the chromosome cycle. FEBS Letters, 579(4) pp. 877-84.

Stillman, Bruce (2005) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Austin, C. P., Battey, J. F., Bradley, A., Bucan, M., Capecchi, M., Collins, F. S., Dove, W. F., Duyk, G., Dymecki, S., Eppig, J. T., Grieder, F. B., Heintz, N., Hicks, G., Insel, T. R., Joyner, A., Koller, B. H., Lloyd, K. C. K., Magnuson, T., Moore, M. W., Nagy, A., Pollock, J. D., Roses, A. D., Sands, A. T., Seed, B., Skarnes, W. C., Snoddy, J., Soriano, P., Stewart, D. J., Stewart, F., Stillman, B., Varmus, H., Varticovski, L., Verma, I. M., Vogt, T. F., von Melchner, H., Witkowski, J., Woychik, R. P., Wurst, W., Yancopoulos, G. D., Young, S. G. , Zambrowicz, B. (2004) The knockout mouse project. Nature Genetics, 36(9) pp. 921-924.

Prasanth, S. G., Prasanth, K. V., Siddiqui, K., Spector, D. L. , Stillman, B. (2004) Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance. EMBO J, 23(13) pp. 2651-63.

Ekholm-Reed, S., Mendez, J., Tedesco, D., Zetterberg, A., Stillman, B. , Reed, S. I. (2004) Deregulation of cyclin E in human cells interferes with prereplication complex assembly. Journal of Cell Biology, 165(6) pp. 789-800.

Prasanth, S. G., Mendez, J., Prasanth, K. V. , Stillman, B. (2004) Dynamics of pre-replication complex proteins during the cell division cycle. Philos Trans R Soc Lond B Biol Sci, 359(1441) pp. 7-16.

Stillman, Bruce (2004) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Mendez, J. , Stillman, B. (2003) Perpetuating the double helix: molecular machines at eukaryotic DNA replication origins. Bioessays, 25(12) pp. 1158-1167.

Ellison, V. , Stillman, B. (2003) Biochemical characterization of DNA damage checkpoint complexes: Clamp loader and clamp complexes with specificity for 5' recessed DNA. Plos Biology, 1(2) pp. 231-243.

Hoek, M. , Stillman, B. (2003) Chromatin assembly factor 1 is essential and couples chromatin assembly to DNA replication in vivo. Proceedings of the National Academy of Sciences of the United States of America, 100(21) pp. 12183-12188.

Stillman, Bruce (2003) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Prasanth, S. G., Prasanth, K. V. , Stillman, B. (2002) ORC, a replication initiator protein required for multiple aspects of cell division cycle. Molecular Biology of the Cell, 13 pp. 282A-282A.

Zhang, Z. G., Hayashi, M. K., Merkel, O., Stillman, B. , Xu, R. M. (2002) Structure and function of the BAH-containing domain of Orc1p in epigenetic silencing. Embo Journal, 21(17) pp. 4600-4611.

Prasanth, S. G., Prasanth, K. V. , Stillman, B. (2002) Orc6 involved in DNA replication, chromosome segregation, and cytokinesis. Science, 297(5583) pp. 1026-31.

Du, Y. C. N. , Stillman, B. (2002) Yph1p, an ORC-interacting protein: Potential links between cell proliferation control, DNA replication, and ribosome biogenesis. Cell, 109(7) pp. 835-848.

Takahashi, N., Tsutsumi, S., Tsuchiya, T., Stillman, B. , Mizushima, T. (2002) Functions of sensor 1 and sensor 2 regions of Saccharomyces cerevisiae Cdc6p in vivo and in vitro. Journal of Biological Chemistry, 277(18) pp. 16033-16040.

Mendez, J., Zou-Yang, X. H., Kim, S. Y., Hidaka, M., Tansey, W. P. , Stillman, B. (2002) Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication. Molecular Cell, 9(3) pp. 481-491.

Stillman, B. (2002) Biotechnology on Long Island. Newsday,

Stillman, Bruce (2002) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Stillman, B. (2001) DNA replication - Genomic views of genome duplication. Science, 294(5550) pp. 2301-2304.

Du, N. , Stillman, B. (2001) Identification and characterization of ORC-interacting protein: Yph1p in Saccharomyces cerevisiae. Clinical Cancer Research, 7(11) pp. 3793S-3793S.

Ellison, V. , Stillman, B. (2001) Opening of the clamp: An intimate view of an ATP-driven biological machine. Cell, 106(6) pp. 655-660.

Weinreich, M., Liang, C., Chen, H. H. , Stillman, B. (2001) Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle. Proceedings of the National Academy of Sciences of the United States of America, 98(20) pp. 11211-11217.

Stillman, B. (2001) The stem cell decision: is this human?. Newsday, pp. B4.

Ola, A., Waga, S., Ellison, V., Stillman, B., McGurk, M., Leigh, I. M., Waseem, N. H. , Waseem, A. (2001) Human-Saccharomyces cerevisiae proliferating cell nuclear antigen hybrids - Oligomeric structure and functional characterization using in vitro DNA replication. Journal of Biological Chemistry, 276(13) pp. 10168-10177.

Kaya, H., Shibahara, K., Taoka, K., Iwabuchi, M., Stillman, B. , Araki, T. (2001) FASCIATA genes for chromatin assembly factor-1 in Arabidopsis maintain the cellular organization of apical meristems. Cell, 104(1) pp. 131-142.

Stillman, Bruce (2001) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Mendez, J. , Stillman, B. (2000) Chromatin association of human origin recognition complex, Cdc6, and minichromosome maintenance proteins during the cell cycle: Assembly of prereplication complexes in late mitosis. Molecular and Cellular Biology, 20(22) pp. 8602-8612.

Zhang, Z. G., Shibahara, K. , Stillman, B. (2000) PCNA connects DNA replication to epigenetic inheritance in yeast. Nature, 408(6809) pp. 221-225.

Mizushima, T., Takahashi, N. , Stillman, B. (2000) Cdc6p modulates the structure and DNA binding activity of the origin recognition complex in vitro. Genes & Development, 14(13) pp. 1631-1641.

Shibahara, K., Verreault, A. , Stillman, B. (2000) The N-terminal domains of histones H3 and H4 are not necessary for chromatin assembly factor-1-mediated nucleosome assembly onto replicated DNA in vitro. Proceedings of the National Academy of Sciences of the United States of America, 97(14) pp. 7766-7771.

Zou, L. , Stillman, B. (2000) Assembly of a complex containing Cdc45p, replication protein A, and Mcm2p at replication origins controlled by S-phase cyclin-dependent kinases and Cdc7p-Dbf4p kinase. Molecular and Cellular Biology, 20(9) pp. 3086-3096.

Chong, J. P. J., Hayashi, M. K., Simon, M. N., Xu, R. M. , Stillman, B. (2000) A double-hexamer archaeal minichromosome maintenance protein is an ATP-dependent DNA helicase. Proceedings of the National Academy of Sciences of the United States of America, 97(4) pp. 1530-1535.

Stillman, Bruce (2000) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Reed, S. H., Akiyama, M., Stillman, B. , Friedberg, E. C. (1999) Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair. Genes and Development, 13(23) pp. 3052-3058.

Weinreich, M. , Stillman, B. (1999) Cdc7p-Dbf4p kinase binds to chromatin during S phase and is regulated by both the APC and the RAD53 checkpoint pathway. EMBO Journal, 18(19) pp. 5334-46.

Iizuka, M. , Stillman, B. (1999) Histone acetyltransferase HBO1 interacts with the ORC1 subunit of the human initiator protein. Journal of Biological Chemistry, 274(33) pp. 23027-34.

Shibahara, K. , Stillman, B. (1999) Replication-dependent marking of DNA by PCNA facilitates CAF-1-coupled inheritance of chromatin. Cell, 96(4) pp. 575-85.

Weinreich, M., Liang, C. , Stillman, B. (1999) The Cdc6p nucleotide-binding motif is required for loading mcm proteins onto chromatin. Proceedings of the National Academy of Sciences of the United States of America, 96(2) pp. 441-6.

Murzina, N., Verreault, A., Laue, E. , Stillman, B. (1999) Heterochromatin Dynamics in Mouse Cells: Interaction between Chromatin Assembly Factor 1 and HP1 Proteins. Molecular Cell, 4(4) pp. 529-540.

Stillman, Bruce (1999) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Tugal, T., Zou-Yang, X. H., Gavin, K., Pappin, D., Canas, B., Kobayashi, R., Hunt, T. , Stillman, B. (1998) The Orc4p and Orc5p Subunits of the Xenopus and Human Origin Recognition Complex Are Related to Orc1p and Cdc6p. Journal of Biological Chemistry, 273(49) pp. 32421-32429.

Waga, S. , Stillman, B. (1998) Cyclin-dependent kinase inhibitor p21 modulates the DNA primer-template recognition complex. Molecular and Cellular Biology, 18(7) pp. 4177-87.

Zou, L. , Stillman, B. (1998) Formation of a preinitiation complex by S-phase cyclin CDK-dependent loading of Cdc45p onto chromatin. Science, 280(5363) pp. 593-6.

Ni, T. H., McDonald, W. F., Zolotukhin, I., Melendy, T., Waga, S., Stillman, B. , Muzyczka, N. (1998) Cellular proteins required for adeno-associated virus DNA replication in the absence of adenovirus coinfection. Journal of Virology, 72(4) pp. 2777-87.

Yan, Z., DeGregori, J., Shohet, R., Leone, G., Stillman, B., Nevins, J. R. , Williams, R. S. (1998) Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 95(7) pp. 3603-3608.

Ellison, V. , Stillman, B. (1998) Reconstitution of recombinant human replication factor C (RFC) and identification of an RFC subcomplex possessing DNA-dependent ATPase activity. Journal of Biological Chemistry, 273(10) pp. 5979-87.

Li, R., Yu, D. S., Tanaka, M., Zheng, L., Berger, S. L. , Stillman, B. (1998) Activation of Chromosomal DNA Replication in Saccharomyces cerevisiae by Acidic Transcriptional Activation Domains. Molecular and Cellular Biology, 18(3) pp. 1296-1302.

Verreault, A., Kaufman, P. D., Kobayashi, R. , Stillman, B. (1998) Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase. Current Biology, 8(2) pp. 96-108.

Stillman, Bruce (1998) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Waga, S. , Stillman, B. (1998) The DNA replication fork in eukaryotic cells. Annual Review of Biochemistry, 67 pp. 721-51.

Liang, C. , Stillman, B. (1997) Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants. Genes and Development, 11(24) pp. 3375-86.

Funk, J. O., Waga, S., Harry, J. B., Espling, E., Stillman, B. , Galloway, D. A. (1997) Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes and Development, 11(16) pp. 2090-2100.

Waga, S., Li, R. , Stillman, B. (1997) p53-induced p21 controls DNA replication. Leukemia, 11 Sup pp. 321-3.

Kaufman, P. D., Kobayashi, R. , Stillman, B. (1997) Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I. Genes and Development, 11(3) pp. 345-57.

Zou, L., Mitchell, J. , Stillman, B. (1997) CDC45, a novel yeast gene that functions with the origin recognition complex and Mcm proteins in initiation of DNA replication. Molecular and Cellular Biology, 17(2) pp. 553-63.

Carpino, N., Wisniewski, D., Strife, A., Marshak, D., Kobayashi, R., Stillman, B. , Clarkson, B. (1997) p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell, 88(2) pp. 197-204.

Williams, R. S., Shohet, R. V. , Stillman, B. (1997) A human protein related to yeast Cdc6p. Proceedings of the National Academy of Sciences of the United States of America, 94(1) pp. 142-7.

Korf, B. R., Casper, E., Friedman, J., Gutmann, D., North, K., Seizinger, G., Stillman, B. W., Rubenstein, A. E. , Bellermann, P. R. W. (1997) Report of the National Neurofibromatosis Foundation (NNFF) Task Force on Treatment of Neurofibromatosis 1. The National Neurofibromatosis Foundation, Inc..

Stillman, Bruce (1997) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Stillman, B. (1996) Cell cycle control of DNA replication. Science, 274(5293) pp. 1659-64.

Verreault, A., Kaufman, P. D., Kobayashi, R. , Stillman, B. (1996) Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. Cell, 87(1) pp. 95-104.

Gaillard, P. H., Martini, E. M., Kaufman, P. D., Stillman, B., Moustacchi, E. , Almouzni, G. (1996) Chromatin assembly coupled to DNA repair: a new role for chromatin assembly factor I. Cell, 86(6) pp. 887-96.

Simmons, D. T., Melendy, T., Usher, D. , Stillman, B. (1996) Simian virus 40 large T antigen binds to topoisomerase I. Virology, 222(2) pp. 365-74.

Green, M. R. , Stillman, B. (1996) Chromosomes and expression mechanisms. Current Opinion in Genetics & Development, 6(2) pp. 139-40.

Kamakaka, R. T., Bulger, M., Kaufman, P. D., Stillman, B. , Kadonaga, J. T. (1996) Postreplicative chromatin assembly by Drosophila and human chromatin assembly factor 1. Molecular and Cellular Biology, 16(3) pp. 810-817.

Li, Rong, Hannon, G. J., Beach, D. , Stillman, B. (1996) Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage. Current Biology, 6(2) pp. 189-199.

Stillman, B. (1996) Two lives in science: the scientist-administrator. The Journal of NIH Research, 8 pp. 31-32.

Stillman, Bruce (1996) Annual Report. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.

Gavin, K. A., Hidaka, M. , Stillman, B. (1995) Conserved initiator proteins in eukaryotes. Science, 270(5242) pp. 1667-71.

Bell, S. P., Mitchell, J., Leber, J., Kobayashi, R. , Stillman, B. (1995) The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing. Cell, 83(4) pp. 563-8.

Stillman, B. (1995) Cold Spring Harbor Laboratory. Mol Med, 1(7) pp. 715-7.

Cullmann, G., Fien, K., Kobayashi, R. , Stillman, B. (1995) Characterization of the five replication factor C genes of Saccharomyces cerevisiae. Molecular and Cellular Biology, 15(9) pp. 4661-71.

Kaufman, P. D., Kobayashi, R., Kessler, N. , Stillman, B. (1995) The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. Cell, 81(7) pp. 1105-14.

Liang, C., Weinreich, M. , Stillman, B. (1995) ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome. Cell, 81(5) pp. 667-76.

Loo, S., Fox, C. A., Rine, J., Kobayashi, R., Stillman, B. , Bell, S. (1995) The origin recognition complex in silencing, cell cycle progression, and DNA replication. Molecular and Cellular Biology, 6(6) pp. 741-56.

Rao, H. , Stillman, B. (1995) The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators. Proceedings of the National Academy of Sciences of the United States of America, 92(6) pp. 2224-8.

Brush, G. S., Kelly, T. J. , Stillman, B. (1995) Identification of eukaryotic DNA replication proteins using simian virus 40 in vitro replication system. Methods in Enzymology, 262 pp. 522-548.

Rao, H., Marahrens, Y. , Stillman, B. (1994) Functional conservation of multiple elements in yeast chromosomal replicators. Molecular and Cellular Biology, 14(11) pp. 7643-51.

Stillman, B. (1994) Smart machines at the DNA replication fork. Cell, 78(5) pp. 725-8.

Kamakaka, R. T., Kaufman, P. D., Stillman, B., Mitsis, P. G. , Kadonaga, J. T. (1994) Simian virus 40 origin- and T-antigen-dependent DNA replication with Drosophila factors in vitro. Molecular and Cellular Biology, 14(8) pp. 5114-22.

Marahrens, Y. , Stillman, B. (1994) Replicator dominance in a eukaryotic chromosome. Embo Journal, 13(14) pp. 3395-400.

Waga, S. , Stillman, B. (1994) Anatomy of a DNA replication fork revealed by reconstitution of SV40 DNA replication in vitro. Nature, 369(6477) pp. 207-12.

Waga, S., Bauer, G. , Stillman, B. (1994) Reconstitution of complete SV40 DNA replication with purified replication factors. Journal of Biological Chemistry, 269(14) pp. 10923-34.

Stillman, B. (1994) Initiation of Eukaryotic DNA-Replication. Faseb Journal, 8(7) pp. A1323-A1323.

Stillman, B. (1994) Initiation of chromosomal DNA replication in eukaryotes. Lessons from lambda. Journal of Biological Chemistry, 269(10) pp. 7047-50.

Luckow, B., Bunz, F., Stillman, B., Lichter, P. , Schutz, G. (1994) Cloning, Expression, and Chromosomal Localization of the 140-Kilodalton Subunit of Replication Factor-C from Mice and Humans. Molecular and Cellular Biology, 14(3) pp. 1626-1634.

Bell, S. P., Kobayashi, R. , Stillman, B. (1994) Transcriptional Silencing, DNA-Replication, and the Yeast Origin Recognition Complex. Journal of Cellular Biochemistry, 56(S18C) pp. 82-82.

Green, M. R. , Stillman, B. (1994) Chromosomes and expression mechanisms: Editorial overview. Current Opinion in Genetics & Development, 4(2) pp. 183-184.

Li, R., Waga, S., Hannon, G. J., Beach, D. , Stillman, B. (1994) Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. Nature, 371(6497) pp. 534-537.

Waga, S., Hannon, G. J., Beach, D. , Stillman, B. (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature, 369(6481) pp. 574-578.

Bell, S. P., Kobayashi, R. , Stillman, B. (1993) Yeast origin recognition complex functions in transcription silencing and DNA replication. Science, 262(5141) pp. 1844-9.

Bunz, F., Kobayashi, R. , Stillman, B. (1993) cDNAs encoding the large subunit of human replication factor C. Proc Natl Acad Sci U S A, 90(23) pp. 11014-8.

Wun-Kim, K., Upson, R., Young, W., Melendy, T., Stillman, B. , Simmons, D. T. (1993) The DNA-Binding Domain of Simian Virus-40 Tumor-Antigen Has Multiple Functions. Journal of Virology, 67(12) pp. 7608-7611.

Ruppert, J. M. , Stillman, B. (1993) Analysis of a protein-binding domain of p53. Mol Cell Biol, 13(6) pp. 3811-20.

Stillman, B., Bell, S., Fien, K., Marahrens, Y., Melendy, T., Rao, H., Ruppert, J. M. , Waga, S. (1993) Initiation of Virus and Cell-DNA Replication. Journal of Cellular Biochemistry, 53(17D) pp. 6-6.

Melendy, T. , Stillman, B. (1993) An interaction between replication protein A and SV40 T antigen appears essential for primosome assembly during SV40 DNA replication. J Biol Chem, 268(5) pp. 3389-95.

Bell, S. P., Marahrens, Y., Rao, H. , Stillman, B. (1993) The replicon model and eukaryotic chromosomes. Cold Spring Harbor Symposia on Quantitative Biology, 58 pp. 435-442.

Stillman, B. (1993) Cold Spring Harbor Symposia on Quantitative Biology - Foreword. Cold Spring Harbor Symposia on Quantitative Biology, 58 pp. R19-R20.

Stillman, B. (1993) DNA replication: Replicator renaissance. Nature, 366(6455) pp. 506-507.

Stillman, B. (1993) Initiation of chromosome replication in eukaryotic cells. The Harvey Lectures, 88 pp. 115-140.

Van Dyck, E., Foury, F., Stillman, B. , Brill, S. J. (1992) A Single-Stranded-DNA Binding-Protein Required for Mitochondrial-DNA Replication in Saccharomyces-Cerevisiae Is Homologous to Escherichia-Coli Ssb. Embo Journal, 11(9) pp. 3421-3430.

Dutta, A. , Stillman, B. (1992) cdc2 family kinases phosphorylate a human cell DNA replication factor, RPA, and activate DNA replication. Embo J, 11(6) pp. 2189-99.

Bell, S. P. , Stillman, B. (1992) ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. Nature, 357(6374) pp. 128-34.

Diffley, J. F. , Stillman, B. (1992) DNA binding properties of an HMG1-related protein from yeast mitochondria. Journal of Biological Chemistry, 267(5) pp. 3368-74.

Marahrens, Y. , Stillman, B. (1992) A yeast chromosomal origin of DNA replication defined by multiple functional elements. Science, 255(5046) pp. 817-23.

Brill, S. J. , Stillman, B. (1992) DNA-Replication in Human and Yeast-Cells. Faseb Journal, 6(1) pp. A538-A538.

Fien, K. , Stillman, B. (1992) Identification of replication factor C from Saccharomyces cerevisiae: a component of the leading-strand DNA replication complex. Molecular and Cellular Biology, 12(1) pp. 155-63.

Stillman, B. (1992) The Cell Surface - Foreword. Cold Spring Harbor Symposia on Quantitative Biology, 57 pp. R17-R17.

Stillman, B., Bell, S. P., Dutta, A. , Marahrens, Y. (1992) DNA replication and the cell cycle. Regulation of the eukaryotic cell cycle. Ciba Foundation symposium, 170 pp. 147-156; discussion 156.

Yanagida, M., Wang, J. Y. J, Hunter, C. T., Morris, N. R., Sherr, C., Stillman, B., Cross, F. R., Kirschner, M. W., Beach, D. , Hunt, T. (1992) Regulation of the Eukaryotic Cell-Cycle - Final Discussion. Ciba Foundation Symposia, 170 pp. 276-278.

Diffley, J. F. , Stillman, B. (1991) A close relative of the nuclear, chromosomal high-mobility group protein HMG1 in yeast mitochondria. Proceedings of the National Academy of Sciences of the United States of America, 88(17) pp. 7864-8.

Brill, S. J. , Stillman, B. (1991) Replication factor-A from Saccharomyces cerevisiae is encoded by three essential genes coordinately expressed at S phase. Genes and Development, 5(9) pp. 1589-600.

Smith, S. , Stillman, B. (1991) Immunological characterization of chromatin assembly factor I, a human cell factor required for chromatin assembly during DNA replication in vitro. Journal of Biological Chemistry, 266(18) pp. 12041-12047.

Smith, S. , Stillman, B. (1991) Stepwise assembly of chromatin during DNA replication in vitro. Embo J, 10(4) pp. 971-80.

Melendy, T. , Stillman, B. (1991) Purification of DNA polymerase delta as an essential simian virus 40 DNA replication factor. Journal of Biological Chemistry, 266(3) pp. 1942-9.

Tsurimoto, T. , Stillman, B. (1991) Replication factors required for SV40 DNA replication in vitro. I. DNA structure-specific recognition of a primer-template junction by eukaryotic DNA polymerases and their accessory proteins. J Biol Chem, 266(3) pp. 1950-60.

Tsurimoto, T. , Stillman, B. (1991) Replication factors required for SV40 DNA replication in vitro. II. Switching of DNA polymerase alpha and delta during initiation of leading and lagging strand synthesis. Journal of Biological Chemistry, 266(3) pp. 1961-8.

Beach, D., Stillman, B. , Watson, J. D. (1991) Cold Spring Harbor Symposia on Quantitative Biology - Foreword. Cold Spring Harbor Symposia on Quantitative Biology, 56 pp. R21-R22.

Dutta, A., Din, S., Brill, S. J. , Stillman, B. (1991) Phosphorylation of replication protein A: A role for cdc2 kinase in G1/S regulation. Cold Spring Harbor Symposia on Quantitative Biology, 56 pp. 315-324.

Stillman, B., Dutta, A., Melendy, T. , Tsurimoto, T. (1991) Mechanism and Regulation of DNA Replication Lessons from Sv-40. Journal of Cellular Biochemistry - Supplement, 47(S15E) pp. 46.

Diffley, J. F. X. , Stillman, B. (1990) The Initiation of Chromosomal DNA Replication in Eukaryotes. Trends in Genetics, 6(12) pp. 427-432.

Tsurimoto, T., Melendy, T. , Stillman, B. (1990) Sequential initiation of lagging and leading strand synthesis by two different polymerase complexes at the SV40 DNA replication origin. Nature, 346(6284) pp. 534-9.

Ng, L., Prelich, G., Anderson, C. W., Stillman, B. , Fisher, P. A. (1990) Drosophila Proliferating Cell Nuclear Antigen - Structural and Functional Homology with Its Mammalian Counterpart. Journal of Biological Chemistry, 265(20) pp. 11948-11954.

Din, S., Brill, S. J., Fairman, M. P. , Stillman, B. (1990) Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells. Genes Dev, 4(6) pp. 968-77.

Tsurimoto, T. , Stillman, B. (1990) Functions of replication factor C and proliferating-cell nuclear antigen: functional similarity of DNA polymerase accessory proteins from human cells and bacteriophage T4. Proceedings of the National Academy of Sciences of the United States of America, 87(3) pp. 1023-7.

Diffley, J. F. X. , Stillman, B. (1990) Ars Binding Factors in DNA Replication and Transcriptional Silencing. Yeast, 6(SPEC. ) pp. S12.

Tsurimoto, T. , Stillman, B. (1989) Multiple replication factors augment DNA synthesis by the two eukaryotic DNA polymerases, alpha and delta. Embo J, 8(12) pp. 3883-9.

Diffley, J. F. , Stillman, B. (1989) Similarity between the transcriptional silencer binding proteins ABF1 and RAP1. Science, 246(4933) pp. 1034-8.

Brill, S. J. , Stillman, B. (1989) Yeast replication factor-A functions in the unwinding of the SV40 origin of DNA replication. Nature, 342(6245) pp. 92-5.

Diffley, J. F. X. , Stillman, B. (1989) Transcriptional Silencing and Lamins. Nature, 342(6245) pp. 24-24.

Mohr, I. J., Fairman, M. P., Stillman, B. , Gluzman, Y. (1989) Large T-antigen mutants define multiple steps in the initiation of simian virus 40 DNA replication. Journal of Virology, 63(10) pp. 4181-8.

Mohr, I. J., Gluzman, Y., Fairman, M. P., Strauss, M., McVey, D., Stillman, B. , Gerard, R. D. (1989) Production of simian virus 40 large tumor antigen in bacteria: altered DNA-binding specificity and dna-replication activity of underphosphorylated large tumor antigen. Proceedings of the National Academy of Sciences of the United States of America, 86(17) pp. 6479-83.

Tsurimoto, T., Fairman, M. P. , Stillman, B. (1989) Simian virus 40 DNA replication in vitro: identification of multiple stages of initiation. Molecular & Cellular Biology, 9(9) pp. 3839-49.

Smith, S. , Stillman, B. (1989) Purification and characterization of CAF-I, a human cell factor required for chromatin assembly during DNA replication in vitro. Cell, 58(1) pp. 15-25.

Tsurimoto, T. , Stillman, B. (1989) Purification of a cellular replication factor, RF-C, that is required for coordinated synthesis of leading and lagging strands during simian virus 40 DNA replication in vitro. Molecular & Cellular Biology, 9(2) pp. 609-19.

Diffley, J. F. X. , Stillman, B. (1989) Origin Binding Proteins from Yeast. Journal of Cellular Biochemistry, 41(S13D) pp. 152.

Fairman, M. P., Prelich, G., Tsurimoto, T. , Stillman, B. (1989) Replication of SV40 in vitro using proteins derived from a human cell extract. J Cell Sci Suppl, 12 pp. 161-9.

Smith, S. , Stillman, B. (1989) Purification and Characterization of a Replication-Dependent Chromatin Assembly Factor Isolated from Human Cells. Journal of Cellular Biochemistry - Supplement.(13 PART D), pp. 173.

Stillman, B. (1989) Initiation of eukaryotic DNA replication in vitro. Annual Review of Cell Biology, 5 pp. 197-245.

Stillman, B., Fairman, M. P., Din, S. U. , Tsurimoto, T. (1989) DNA Replication in-Vitro from the Sv-40 Origin. Journal of Cellular Biochemistry - Supplement.(13 PART D), 41(S13D) pp. 73.

Fairman, M., Prelich, G., Tsurimoto, T. , Stillman, B. (1988) Identification of cellular components required for SV40 DNA replication in vitro. Biochim Biophys Acta, 951(2-3) pp. 382-7.

White, E., Denton, A. , Stillman, B. (1988) Role of the adenovirus E1B 19,000-dalton tumor antigen in regulating early gene expression. Journal of Virology, 62(9) pp. 3445-54.

Stillman, B. (1988) Initiation of eukaryotic DNA replication in vitro. Bioessays, 9(2-3) pp. 56-60.

Heintz, N. H. , Stillman, B. W. (1988) Nuclear-DNA Synthesis Invitro Is Mediated Via Stable Replication Forks Assembled in a Temporally Specific Fashion In vivo. Molecular and Cellular Biology, 8(5) pp. 1923-1931.

Prelich, G. , Stillman, B. (1988) Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA. Cell, 53(1) pp. 117-26.

Diffley, J. F. , Stillman, B. (1988) Purification of a yeast protein that binds to origins of DNA replication and a transcriptional silencer. Proceedings of the National Academy of Sciences of the United States of America, 85(7) pp. 2120-4.

Fairman, M. P. , Stillman, B. (1988) Cellular factors required for multiple stages of SV40 DNA replication in vitro. Embo Journal, 7(4) pp. 1211-8.

Fairman, M. P., Prelich, G. , Stillman, B. (1987) Identification of multiple cellular factors required for SV40 replication in vitro. Philos Trans R Soc Lond B Biol Sci, 317(1187) pp. 495-505.

Prelich, G., Kostura, M., Marshak, D. R., Mathews, M. B. , Stillman, B. (1987) The cell-cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro. Nature, 326(6112) pp. 471-475.

Prelich, G., Tan, C. K., Kostura, M., Mathews, M. B., So, A. G., Downey, K. M. , Stillman, B. (1987) Functional identity of proliferating cell nuclear antigen and a DNA polymerase-delta auxiliary protein. Nature, 326(6112) pp. 517-20.

White, E. , Stillman, B. (1987) Expression of adenovirus E1B mutant phenotypes is dependent on the host cell and on synthesis of E1A proteins. Journal of Virology, 61(2) pp. 426-35.

Mohr, I. J., Stillman, B. , Gluzman, Y. (1987) Regulation of SV40 DNA replication by phosphorylation of T antigen. Embo J, 6(1) pp. 153-60.

White, E., Denton, A. , Stillman, B. (1987) Regulation of Adenovirus Early Gene-Expression by the E1b 19k Tumor-Antigen. Journal of Cellular Biochemistry, 35(S11C) pp. 152-152.

Ostapchuk, P., Diffley, J. F. X., Bruder, J. T., Stillman, B., Levine, A. J. , Hearing, P. (1986) Interaction of a Nuclear Factor with the Polyomavirus Enhancer Region. Proceedings of the National Academy of Sciences of the United States of America, 83(22) pp. 8550-8554.

White, E., Faha, B. , Stillman, B. (1986) Regulation of Adenovirus Gene-Expression in Human Wi38 Cells by an E1b-Encoded Tumor-Antigen. Molecular and Cellular Biology, 6(11) pp. 3763-3773.

Stillman, B. (1986) Chromatin assembly during SV40 DNA replication in vitro. Cell, 45(4) pp. 555-65.

Diffley, J. F. , Stillman, B. (1986) Purification of a cellular, double-stranded DNA-binding protein required for initiation of adenovirus DNA replication by using a rapid filter-binding assay. Molecular and Cellular Biology, 6(5) pp. 1363-73.

Prelich, G. , Stillman, B. W. (1986) Functional-Characterization of Thermolabile DNA-Binding Proteins That Affect Adenovirus DNA-Replication. Journal of Virology, 57(3) pp. 883-892.

Diffley, J. F. X. , Stillman, B. W. (1986) Characterization of Protein Which Binds Specifically to a Putative Origin of Cellular DNA-Replication. Journal of Cellular Biochemistry, 32(S10B) pp. 229-229.

Stillman, B. (1986) Functions of the adenovirus E1B tumour antigens. Cancer Surv, 5(2) pp. 389-404.

Stillman, B., Gerard, R. D., Guggenheimer, R. A. , Gluzman, Y. (1985) T antigen and template requirements for SV40 DNA replication in vitro. EMBO Journal, 4(11) pp. 2933-2939.

Stillman, B. W. , Gluzman, Y. (1985) Replication and Supercoiling of Sv-40 DNA in Cell Extracts from Human Cells. Molecular & Cellular Biology, 5(8) pp. 2051-2060.

Guggenheimer, R. A., Stillman, B. W., Nagata, K., Tamanoi, F. , Hurwitz, J. (1984) DNA-Sequences Required for the Invitro Replication of Adenovirus DNA. Proceedings of the National Academy of Sciences of the United States of America-Biological Sciences, 81(10) pp. 3069-3073.

Stillman, B. W., White, E. , Grodzicker, T. (1984) Independent Mutations in Adenovirus Type 2 Ts-111 Cause Degradation of Cellular DNA and Defective Viral DNA Replication. Journal of Virology, 50(2) pp. 598-605.

Tamanoi, F. , Stillman, B. W. (1984) The origin of adenovirus DNA replication. Current Topics in Microbiology and Immunology, 109 pp. 75-87.

White, E., Blose, S. H. , Stillman, B. W. (1984) Nuclear-Envelope Localization of an Adenovirus Tumor-Antigen Maintains the Integrity of Cellular DNA. Molecular and Cellular Biology, 4(12) pp. 2865-2875.

White, E., Grodzicker, T. , Stillman, B. W. (1984) Mutations in the Gene Encoding the Adenovirus Early Region-1b 19,000-Molecular-Weight Tumor-Antigen Cause the Degradation of Chromosomal DNA. Journal of Virology, 52(2) pp. 410-419.

Stillman, B. W. (1983) The replication of adenovirus DNA with purified proteins. Cell, 35(1) pp. 7-9.

Tamanoi, F. , Stillman, B. W. (1983) Initiation of adenovirus DNA replication in vitro requires a specific DNA sequence. Proceedings of the National Academy of Sciences of the United States of America, 80(21) pp. 6446-50.

Stillman, B. W. , Tamanoi, F. (1983) Adenoviral DNA replication: DNA sequences and enzymes required for initiation in vitro. Cold Spring Harbor Symposia on Quantitative Biology, 47(2) pp. 741-750.

Stillman, B. W. , Tamanoi, F. (1983) The Interaction of Proteins and DNA Sequences Required for Adenovirus DNA Replication in-Vitro. Journal of Cellular Biochemistry, 21(S7A) pp. 130.

Stillman, B. W., Tamanoi, F. , Mathews, M. B. (1982) Purification of an adenovirus-coded DNA polymerase that is required for initiation of DNA replication. Cell, 31(3 Pt 2) pp. 613-23.

Stillman, B. W., Topp, W. C. , Engler, J. A. (1982) Conserved sequences at the origin of adenovirus DNA replication. Journal of Virology, 44(2) pp. 530-7.

Tamanoi, F. , Stillman, B. W. (1982) Function of Adenovirus Terminal Protein in the Initiation of DNA Replication. Proceedings of the National Academy of Sciences of the United States of America, 79(7) pp. 2221-2225.

Smart, J. E. , Stillman, B. W. (1982) Adenovirus terminal protein precursor. Partial amino acid sequence and the site of covalent linkage to virus DNA. Journal of Biological Chemistry, 257(22) pp. 13499-13506.

Stillman, B. W. (1981) Adenovirus DNA-Replication Invitro - a Protein Linked to the 5' End of Nascent DNA Strands. Journal of Virology, 37(1) pp. 139-147.

Stillman, B. W., Lewis, J. B., Chow, L. T., Mathews, M. B. , Smart, J. E. (1981) Identification of the Gene and Messenger-Rna for the Adenovirus Terminal Protein-Precursor. Cell, 23(2) pp. 497-508.

Mathews, M. B., Esche, H., Smart, J., Stillman, B. W., Harter, M. , Lewis, J. (1980) Left End Proteins of Adenoviruses. Journal of Supramolecular Structure, 14(S4) pp. 260.

Stillman, B. W. , Bellett, A. J. D. (1979) An adenovirus protein associated with the ends of replicating DNA molecules. Virology, 93(1) pp. 69-79.

Lewis, J. B., Esche, H., Smart, J. E., Stillman, B. W., Harter, M. L. , Mathews, M. B. (1979) Organization and expression of the left third of the genome of adenovirus. Cold Spring Harb Symp Quant Biol, 44(1) pp. 493-508.

Stillman, B. W. , Bellett, A. J. D. (1979) Replication of DNA in adenovirus-infected cells. Cold Spring Harbor Symposia on Quantitative Biology, 43(2) pp. 729-739.

Stillman, B. W., Bellett, A. J. , Robinson, A. J. (1977) Replication of linear adenovirus DNA is not hairpin-primed. Nature, 269(5630) pp. 723-5.