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Safaric Tepes, Polona, Pal, Debjani, Lindsted, Trine, Ibarra, Ingrid, Lujambio, Amaia, Jimenez Sabinina, Vilma, Senturk, Serif, Miller, Madison, Korimerla, Navya, Huang, Jiahao, Glassman, Lawrence, Lee, Paul, Zeltsman, David, Hyman, Kevin, Esposito, Michael, Hannon, Greg, Sordella, Raffaella (July 2021) An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating miR-335 expression. eLife, 10. ISSN 2050-084X

Dokshin, G. A., Davis, G. M., Sawle, A. D., Eldridge, M. D., Nicholls, P. K., Gourley, T. E., Romer, K. A., Molesworth, L. W., Tatnell, H. R., Ozturk, A. R., de Rooij, D. G., Hannon, G. J., Page, D. C., Mello, C. C., Carmell, M. A. (December 2019) GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability. Dev Cell. ISSN 1534-5807 (Public Dataset)

Kneuss, E., Munafo, M., Eastwood, E. L., Deumer, U. S., Preall, J. B., Hannon, G. J., Czech, B. (August 2019) Specialization of the Drosophila nuclear export family protein Nxf3 for piRNA precursor export. Genes Dev, 33 (17-18). pp. 1208-1220. ISSN 0890-9369

Delas, M. J., Jackson, B. T., Kovacevic, T., Vangelisti, S., Munera Maravilla, E., Wild, S. A., Stork, E. M., Erard, N., Knott, S. R. V., Hannon, G. J. (April 2019) lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation. Cell Rep, 27 (3). 719-729.e6.

Sonzogni, O., Haynes, J., Seifried, L. A., Kamel, Y. M., Huang, K., BeGora, M. D., Yeung, F. A., Robert-Tissot, C., Heng, Y. J., Yuan, X., Wulf, G. M., Kron, K. J., Wagenblast, E., Lupien, M., Kislinger, T., Hannon, G. J., Muthuswamy, S. K. (June 2018) Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo. PLoS Biol, 16 (6). e2004049. ISSN 1544-9173

Xie, Y., Cao, Z., Wong, E. W., Guan, Y., Ma, W., Zhang, J. Q., Walczak, E. G., Murphy, D., Ran, L., Sirota, I., Wang, S., Shukla, S., Gao, D., Knott, S. R., Chang, K., Leu, J., Wongvipat, J., Antonescu, C. R., Hannon, G., Chi, P., Chen, Y. (April 2018) COP1-DET1-ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors. J Clin Invest, 128 (4). pp. 1442-1457. ISSN 0021-9738

Xie, Y., Cao, Z., Wong, E. W., Guan, Y., Ma, W., Zhang, J. Q., Walczak, E. G., Murphy, D., Ran, L., Sirota, I., Wang, S., Shukla, S., Gao, D., Knott, S. R., Chang, K., Leu, J., Wongvipat, J., Antonescu, C. R., Hannon, G., Chi, P., Chen, Y. (April 2018) COP1/DET1/ETS axis regulates ERK transcriptome and sensitivity to MAPK inhibitors. J Clin Invest, 128 (4). pp. 1442-1457. ISSN 0021-9738 (Print)0021-9738

Knott, S. R. V., Wagenblast, E., Khan, S., Kim, S. Y., Soto, M., Wagner, M., Turgeon, M. O., Fish, L., Erard, N., Gable, A. L., Maceli, A. R., Dickopf, S., Papachristou, E. K., D'Santos, C. S., Carey, L. A., Wilkinson, J. E., Harrell, J. C., Perou, C. M., Goodarzi, H., Poulogiannis, G., Hannon, G. J. (February 2018) Asparagine bioavailability governs metastasis in a model of breast cancer. Nature, 554 (7692). pp. 378-381. ISSN 0028-0836

Qu, J., Hodges, E., Molaro, A., Gagneux, P., Dean, M. D., Hannon, G. J., Smith, A. D. (February 2018) Evolutionary expansion of DNA hypomethylation in the mammalian germline genome. Genome Research, 28 (2). pp. 145-158. ISSN 10889051

Xie, Y. Y., Cao, Z., Wong, W. P., Guan, Y. X., Zhang, J., Walczak, E., Murphy, D., Ran, L., Sirota, I., Wang, S. Q., Shukla, S., Gao, D., Wongvipat, J., Knott, S., Chang, K., Antonescu, C., Hannon, G., Chi, P., Chen, Y. (January 2018) COP1-ETS axis regulates ERK transcriptional output and modulates sensitivity to MAPK inhibitors. Clinical Cancer Research, 24 (2 Supp). p. 61. ISSN 1078-0432

Delas, M. J., Sabin, L. R., Dolzhenko, E., Knott, S. R., Munera Maravilla, E., Jackson, B. T., Wild, S. A., Kovacevic, T., Stork, E. M., Zhou, M., Erard, N., Lee, E., Kelley, D. R., Roth, M., Barbosa, I. S. A., Zuber, J., Rinn, J. L., Smith, A. D., Hannon, G. J. (September 2017) lncRNA requirements for mouse acute myeloid leukemia and normal differentiation. Elife, 6. e25607. ISSN 2050-084x

Frey, W. D., Chaudhry, A., Slepicka, P. F., Ouellette, A. M., Kirberger, S. E., Pomerantz, W. C. K., Hannon, G. J., Dos Santos, C. O. (July 2017) BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells. Stem Cell Reports, 9 (1). pp. 23-31. ISSN 2213-6711 (Public Dataset)

Delas, M. J., Hannon, G. J. (July 2017) lncRNAs in development and disease: from functions to mechanisms. Open Biol, 7 (7). ISSN 2046-2441

Pal, D., Pertot, A., Shirole, N. H., Yao, Z., Anaparthy, N., Garvin, T., Cox, H., Chang, K., Rollins, F., Kendall, J., Edwards, L., Singh, V. A., Stone, G. C., Schatz, M. C., Hicks, J., Hannon, G., Sordella, R. (January 2017) TGF-beta reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells. Elife, 6. ISSN 2050-084X (Electronic)2050-084X (Linking)

Erard, Nicolas, Knott, Simon R. V., Hannon, Gregory J. (2017) A CRISPR Resource for Individual, Combinatorial, or Multiplexed Gene Knockout. Molecular Cell, 67 (2). 348-354.e3. ISSN 1097-2765

McFadden, D. G., Politi, K., Bhutkar, A., Chen, F. K., Song, X., Pirun, M., Santiago, P. M., Kim-Kiselak, C., Platt, J. T., Lee, E., Hodges, E., Rosebrock, A. P., Bronson, R. T., Socci, N. D., Hannon, G. J., Jacks, T., Varmus, H. (October 2016) Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma. Proc Natl Acad Sci U S A, 113 (42). E6409-E6417. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Fagegaltier, D., Falciatori, I., Czech, B., Castel, S., Perrimon, N., Simcox, A., Hannon, G. J. (July 2016) Oncogenic transformation of Drosophila somatic cells induces a functional piRNA pathway. Genes Dev, 30 (14). pp. 1623-35. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Hammell, Christopher M, Hannon, Gregory J (January 2016) Inducing RNAi in Caenorhabditis elegans by Injection of dsRNA. Cold Spring Harbor protocols, 2016 (1). pdb.prot086306. ISSN 1940-3402

Sanchez, Carlos G, Teixeira, Felipe Karam, Czech, Benjamin, Preall, Jonathan B, Zamparini, Andrea L, Seifert, Jessica R K., Malone, Colin D, Hannon, Gregory J, Lehmann, Ruth (December 2015) Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation. Cell Stem Cell, 18 (2). pp. 276-290. ISSN 1934-5909

Zhou, X., Battistoni, G., El Demerdash, O., Gurtowski, J., Wunderer, J., Falciatori, I., Ladurner, P., Schatz, M. C., Hannon, G. J., Wasik, K. A. (November 2015) Dual functions of Macpiwi1 in transposon silencing and stem cell maintenance in the flatworm Macrostomum lignano. RNA, 21 (11). pp. 1885-1897. ISSN 1469-9001 (Electronic)1355-8382 (Linking)

Yu, Y., Gu, J., Jin, Y., Luo, Y., Preall, J. B., Ma, J., Czech, B., Hannon, G. J. (October 2015) Panoramix enforces piRNA-dependent cotranscriptional silencing. Science, 350 (6258). pp. 339-42. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

Dequeant, M. L., Fagegaltier, D., Hu, Y., Spirohn, K., Simcox, A., Hannon, G. J., Perrimon, N. (October 2015) Discovery of progenitor cell signatures by time-series synexpression analysis during Drosophila embryonic cell immortalization. Proc Natl Acad Sci U S A, 112 (42). pp. 12974-12979. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Wasik, K., Gurtowski, J., Zhou, X., Ramos, O. M., Delas, M. J., Battistoni, G., El Demerdash, O., Falciatori, I., Vizoso, D. B., Smith, A. D., Ladurner, P., Scharer, L., McCombie, W. R., Hannon, G. J., Schatz, M. (September 2015) Genome and transcriptome of the regeneration-competent flatworm, Macrostomum lignano. Proc Natl Acad Sci U S A, 112 (40). pp. 12462-12467. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Wasik, K. A., Tam, O. H., Knott, S. R., Falciatori, I., Hammell, M., Vagin, V. V., Hannon, G. J. (June 2015) RNF17 blocks promiscuous activity of PIWI proteins in mouse testes. Genes Dev, 29 (13). pp. 1403-1415. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Goh, W. S., Falciatori, I., Tam, O. H., Burgess, R., Meikar, O., Kotaja, N., Hammell, M., Hannon, G. J. (May 2015) piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis. Genes Dev, 29 (10). pp. 1032-44. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Dos Santos, C. O., Dolzhenko, E., Hodges, E., Smith, A. D., Hannon, G. J. (May 2015) An Epigenetic Memory of Pregnancy in the Mouse Mammary Gland. Cell Reports. ISSN 2211-1247

Teixeira, F. K., Sanchez, C. G., Hurd, T. R., Seifert, J. R., Czech, B., Preall, J. B., Hannon, G. J., Lehmann, R. (April 2015) ATP synthase promotes germ cell differentiation independent of oxidative phosphorylation. Nature Cell Biology, 17 (5). pp. 689-696. ISSN 1465-7392

Wagenblast, E., Soto, M., Gutierrez-Angel, S., Hartl, C. A., Gable, A. L., Maceli, A. R., Erard, N., Williams, A. M., Kim, S. Y., Dickopf, S., Harrell, J. C., Smith, A. D., Perou, C. M., Wilkinson, J. E., Hannon, G. J., Knott, S. R. (April 2015) A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis. Nature, 520 (7547). pp. 358-362. ISSN 0028-0836

Marinov, Georgi K, Wang, Jie, Handler, Dominik, Wold, Barbara J, Weng, Zhiping, Hannon, Gregory J, Aravin, Alexei A, Zamore, Phillip D, Brennecke, Julius, Toth, Katalin Fejes (March 2015) Pitfalls of Mapping High-Throughput Sequencing Data to Repetitive Sequences: Piwi’s Genomic Targets Still Not Identified. Developmental Cell, 32 (6). pp. 765-771. ISSN 1534-5807

Stein, P., Rozhkov, N. V., Li, F., Cardenas, F. L., Davydenk, O., Vandivier, L. E., Gregory, B. D., Hannon, G. J., Schultz, R. M. (February 2015) Essential Role for Endogenous siRNAs during Meiosis in Mouse Oocytes. PLoS Genetics, 11 (2). e1005013. ISSN 1553-7390

Knott, S. R., Maceli, A. R., Erard, N., Chang, K., Marran, K., Zhou, X., Gordon, A., El Demerdash, O., Wagenblast, E., Kim, S., Fellmann, C., Hannon, G. J. (December 2014) A Computational Algorithm to Predict shRNA Potency. Mol Cell, 56 (6). pp. 796-807. ISSN 1097-2765

Malaspinas, Anna-Sapfo, Lao, Oscar, Schroeder, Hannes, Rasmussen, Morten, Raghavan, Maanasa, Moltke, Ida, Campos, Paula F., Sagredo, Francisca Santana, Rasmussen, Simon, Gonçalves, Vanessa F., Albrechtsen, Anders, Allentoft, Morten E., Johnson, Philip L. F., Li, Mingkun, Reis, Silvia, Bernardo, Danilo V., DeGiorgio, Michael, Duggan, Ana T., Bastos, Murilo, Wang, Yong, Stenderup, Jesper, Moreno-Mayar, J. Victor, Brunak, Søren, Sicheritz-Ponten, Thomas, Hodges, Emily, Hannon, Gregory J., Orlando, Ludovic, Price, T. Douglas, Jensen, Jeffrey D., Nielsen, Rasmus, Heinemeier, Jan, Olsen, Jesper, Rodrigues-Carvalho, Claudia, Lahr, Marta Mirazón, Neves, Walter A., Kayser, Manfred, Higham, Thomas, Stoneking, Mark, Pena, Sergio D. J., Willerslev, Eske (November 2014) Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil. Current Biology, 24 (21). R1035-R1037. ISSN 0960-9822

Premsrirut, P. K., Yoon, B., Pesic, M., Dow, L. E., Zuber, J., Lowe, S. W., Hannon, G. J., Zender, L., Fellmann, C. (October 2014) RNAi mouse models: Revolutionizing drug discovery in vivo. Cancer Research, 74 (19). Abstract#2974. ISSN 0008-5472

Deng, L., Shang, L., Bai, S., Chen, J., He, X., Trevino, R. M., Chen, S., Li, X., Meng, X., Yu, B., Wang, X., Liu, Y., McDermott, S. P., Ariazi, A. E., Ginestier, C., Ibarra, I., Ke, J., Luther, T. K., Clouthier, S. G., Xu, L., Shan, G., Song, E., Yao, H., Hannon, G. J., Weiss, S. J., Wicha, M. S., Liu, S. (September 2014) microRNA100 inhibits self-renewal of breast cancer stem-like cells and breast tumor development. Cancer Res, 74 (22). pp. 6648-6660. ISSN 0008-5472

Yang, M., Haase, A. D., Huang, F. K., Coulis, G., Rivera, K. D., Dickinson, B. C., Chang, C. J., Pappin, D. J., Neubert, T. A., Hannon, G. J., Boivin, B., Tonks, N. K. (August 2014) Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence. Mol Cell, 55 (5). pp. 782-790. ISSN 1097-2765

Fagegaltier, D., Konig, A., Gordon, A., Lai, E. C., Gingeras, T. R., Hannon, G. J., Shcherbata, H. R. (July 2014) A Genome-Wide Survey of Sexually Dimorphic Expression of Drosophila miRNAs Identifies the Steroid Hormone-Induced miRNA let-7 as a Regulator of Sexual Identity. Genetics, 198 (2). pp. 647-668. ISSN 0016-6731

Molaro, A., Falciatori, I., Hodges, E., Aravin, A. A., Marran, K., Rafii, S., McCombie, W. R., Smith, A. D., Hannon, G. J. (July 2014) Two waves of de novo methylation during mouse germ cell development. Genes and Development, 28 (14). pp. 1544-9. ISSN 08909369 (ISSN)

Rechavi, Oded, Houri-Ze’evi, Leah, Anava, Sarit, Goh, Wee Siong Sho, Kerk, Sze Yen, Hannon, Gregory J, Hobert, Oliver (July 2014) Starvation-Induced Transgenerational Inheritance of Small RNAs in C. elegans. Cell, 158 (2). pp. 277-287. ISSN 0092-8674

Meikar, O., Vagin, V. V., Chalmel, F., Sostar, K., Lardenois, A., Hammell, M., Jin, Y., Da Ros, M., Wasik, K. A., Toppari, J., Hannon, G. J., Kotaja, N. (April 2014) An atlas of chromatoid body components. RNA, 20 (4). pp. 483-95. ISSN 1355-8382

Goh, W. S. S., Seah, J. W. E., Harrison, E. J., Chen, C., Hammell, C. M., Hannon, G. J. (April 2014) A genome-wide RNAi screen identifies factors required for distinct stages of C-elegans piRNA biogenesis. Genes & Development, 28 (7). pp. 797-807. ISSN 0890-9369

Faehnle, C. R., Elkayam, E., Haase, A. D., Hannon, G. J., Joshua-Tor, L. (January 2014) Slicer and the Argonautes. Biophysical Journal, 106 (2; Sup). 455A-455A. ISSN 0006-3495

Chang, K., Marran, K., Valentine, A., Hannon, G. J. (2014) Generation of transgenic drosophila expressing shRNAs in the miR-1 backbone. Cold Spring Harbor Protocols, 2014 (5). pp. 501-509. ISSN 19403402

Siolas, D., Hannon, G. J. (September 2013) Patient-derived tumor xenografts: Transforming clinical samples into mouse models. Cancer Research, 73 (17). pp. 5315-5319. ISSN 00085472 (ISSN)

Hauser, F., Chen, W. X., Deinlein, U., Chang, K., Ossowski, S., Fitz, J., Hannon, G. J., Schroeder, J. I. (August 2013) A Genomic-Scale Artificial MicroRNA Library as a Tool to Investigate the Functionally Redundant Gene Space in Arabidopsis. Plant Cell, 25 (8). pp. 2848-2863. ISSN 1040-4651

Karginov, F. V., Hannon, G. J. (July 2013) Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates. Genes and Development, 27 (14). pp. 1624-32. ISSN 08909369 (ISSN)

Schlesinger, F., Smith, A. D., Gingeras, T. R., Hannon, G. J., Hodges, E. (June 2013) De novo DNA demethylation and non-coding transcription define active intergenic regulatory elements. Genome Research, 23 (10). pp. 1601-1614. ISSN 10889051 (ISSN)

Vagin, V. V., Yu, Y., Jankowska, A., Luo, Y., Wasik, K. A., Malone, C. D., Harrison, E., Rosebrock, A., Wakimoto, B. T., Fagegaltier, D., Muerdter, F., Hannon, G. J. (June 2013) Minotaur is critical for primary piRNA biogenesis. RNA, 19 (8). pp. 1064-1077. ISSN 1469-9001 (Electronic)1355-8382 (Linking)

Faehnle, Christopher R, Elkayam, Elad, Haase, Astrid D, Hannon, Gregory J, Joshua-Tor, Leemor (June 2013) The Making of a Slicer: Activation of Human Argonaute-1. Cell Reports, 3 (6). pp. 1901-1909. ISSN 2211-1247 (Public Dataset)

Raddatz, G., Guzzardo, P. M., Olova, N., Fantappié, M. R., Rampp, M., Schaefer, M., Reik, W., Hannon, G. J., Lyko, F. (May 2013) Dnmt2-dependent methylomes lack defined DNA methylation patterns. Proceedings of the National Academy of Sciences of the United States of America, 110 (21). pp. 8627-8631. ISSN 00278424

Muerdter, F., Guzzardo, P. M., Gillis, J., Luo, Y., Yu, Y., Chen, C., Fekete, R., Hannon, G.J. (May 2013) A Genome-wide RNAi Screen Draws a Genetic Framework for Transposon Control and Primary piRNA Biogenesis in Drosophila. Molecular Cell, 50 (5). pp. 736-748. ISSN 1097-4164

Wiggs, J. L., Howell, G. R., Linkroum, K., Abdrabou, W., Hodges, E., Braine, C. E., Pasquale, L. R., Hannon, G. J., Haines, J. L., John, S. W. M. (April 2013) Variations in COL15A1 and COL18A1 influence age of onset of primary open angle glaucoma. Clinical Genetics, 84 (2). p. 167. ISSN 00099163

Lu, X. W., Wontakal, S. N., Kavi, H., Kim, B. J., Guzzardo, P. M., Emelyanov, A. V., Xu, N., Hannon, G. J., Zavadil, J., Fyodorov, D. V., Skoultchi, A. I. (April 2013) Drosophila H1 Regulates the Genetic Activity of Heterochromatin by Recruitment of Su(var)3-9. Science, 340 (6128). pp. 78-81. ISSN 0036-8075

Sabin, L. R., Delas, M. J., Hannon, G. J. (March 2013) Dogma derailed: the many influences of RNA on the genome. Molecular Cell, 49 (5). pp. 783-94. ISSN 1097-2765

Rozhkov, N. V., Hammell, M., Hannon, G. J. (February 2013) Multiple roles for Piwi in silencing Drosophila transposons. Genes and Development, 27 (4). pp. 400-412. ISSN 08909369 (ISSN)

Sabin, L. R., Zheng, Q., Thekkat, P., Yang, J., Hannon, G. J., Gregory, B. D., Tudor, M., Cherry, S. (February 2013) Dicer-2 Processes Diverse Viral RNA Species. PLoS ONE, 8 (2). ISSN 19326203 (ISSN)

Guzzardo, P. M., Muerdter, F., Hannon, G. J. (January 2013) The piRNA pathway in flies: highlights and future directions. Curr Opin Genet Dev, 23 (1). pp. 44-52. ISSN 1879-0380 (Electronic)0959-437X (Linking)

Chang, K., Marran, K., Valentine, A., Hannon, G. J. (2013) Creating an miR30-based shRNA vector. Cold Spring Harbor Protocols, 8 (7). pp. 631-635. ISSN 19403402

Kaaij, L. T. J., van de Wetering, M., Fang, F., Decato, B., Molaro, A., van de Werken, H. J. G., van Es, J. H., Schuijers, J., de Wit, E., de Laat, W., Hannon, G. J., Clevers, H. C., Smith, A. D., Ketting, R. F. (2013) DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus. Genome Biology, 14 (5). ISSN 1465-6906

Chang, K., Marran, K., Valentine, A., Hannon, G. J. (2013) Infection of mammalian cells with retroviral shRNAs. Cold Spring Harbor Protocols, 2013 (8). pp. 732-733. ISSN 19403402

Dos Santos, C. O., Rebbeck, C., Rozhkova, E., Valentine, A., Samuels, A., Kadiri, L. R., Osten, P., Harris, E. Y., Uren, P. J., Smith, A. D., Hannon, G. J. (2013) Molecular hierarchy of mammary differentiation yields refined markers of mammary stem cells. Proceedings of the National Academy of Sciences of the United States of America, 110 (18). pp. 7123-7130. ISSN 0027-8424

Chang, K., Marran, K., Valentine, A., Hannon, G. J. (2013) Packaging shRNA retroviruses. Cold Spring Harbor Protocols, 2013 (8). pp. 734-737. ISSN 19403402

Czech, Benjamin, Preall, Jonathan B, McGinn, Jon, Hannon, Gregory J (2013) A Transcriptome-wide RNAi Screen in the Drosophila Ovary Reveals Factors of the Germline piRNA Pathway. Molecular Cell, 50 (5). pp. 749-761. ISSN 1097-2765

Hammell, C. M., Hannon, G. J. (December 2012) Inducing RNAi in C. elegans by Feeding with dsRNA-expressing E. coli. Cold Spring Harb Protoc, 2012 (12). ISSN 1559-6095 (Electronic)1559-6095 (Linking)

Djebali, S., Davis, C. A., Merkel, A., Dobin, A., Lassmann, T., Mortazavi, A., Tanzer, A., Lagarde, J., Lin, W., Schlesinger, F., Xue, C., Marinov, G. K., Khatun, J., Williams, B. A., Zaleski, C., Rozowsky, J., Röder, M., Kokocinski, F., Abdelhamid, R. F., Alioto, T., Antoshechkin, I., Baer, M. T., Bar, N. S., Batut, P., Bell, K., Bell, I., Chakrabortty, S., Chen, X., Chrast, J., Curado, J., Derrien, T., Drenkow, J., Dumais, E., Dumais, J., Duttagupta, R., Falconnet, E., Fastuca, M., Fejes-Toth, K., Ferreira, P., Foissac, S., Fullwood, M. J., Gao, H., Gonzalez, D., Gordon, A., Gunawardena, H., Howald, C., Jha, S., Johnson, R., Kapranov, P., King, B., Kingswood, C., Luo, O. J., Park, E., Persaud, K., Preall, J. B., Ribeca, P., Risk, B., Robyr, D., Sammeth, M., Schaffer, L., See, L. H., Shahab, A., Skancke, J., Suzuki, A. M., Takahashi, H., Tilgner, H., Trout, D., Walters, N., Wang, H., Wrobel, J., Yu, Y., Ruan, X., Hayashizaki, Y., Harrow, J., Gerstein, M., Hubbard, T., Reymond, A., Antonarakis, S. E., Hannon, G., Giddings, M. C., Ruan, Y., Wold, B., Carninci, P., Guig, R., Gingeras, T. R. (September 2012) Landscape of transcription in human cells. Nature, 489 (7414). pp. 101-108. ISSN 0028-0836

Dunham, I., Kundaje, A., Aldred, S. F., Collins, P. J., Davis, C., Doyle, F., Epstein, C. B., Frietze, S., Harrow, J., Kaul, R., Khatun, J., Lajoie, B. R., Landt, S. G., Lee, B. K., Pauli, F., Rosenbloom, K. R., Sabo, P., Safi, A., Sanyal, A., Shoresh, N., Simon, J. M., Song, L., Trinklein, N. D., Altshuler, R. C., Birney, E., Brown, J. B., Cheng, C., Djebali, S., Dong, X. J., Ernst, J., Furey, T. S., Gerstein, M., Giardine, B., Greven, M., Hardison, R. C., Harris, R. S., Herrero, J., Hoffman, M. M., Iyer, S., Kellis, M., Kheradpour, P., Lassmann, T., Li, Q. H., Lin, X., Marinov, G. K., Merkel, A., Mortazavi, A., Parker, S. C. J., Reddy, T. E., Rozowsky, J., Schlesinger, F., Thurman, R. E., Wang, J., Ward, L. D., Whitfield, T. W., Wilder, S. P., Wu, W., Xi, H. L. S., Yip, K. Y., Zhuang, J. L., Bernstein, B. E., Green, E. D., Gunter, C., Snyder, M., Pazin, M. J., Lowdon, R. F., Dillon, L. A. L., Adams, L. B., Kelly, C. J., Zhang, J., Wexler, J. R., Good, P. J., Feingold, E. A., Crawford, G. E., Dekker, J., Elnitski, L., Farnham, P. J., Giddings, M. C., Gingeras, T. R., Guigo, R., Hubbard, T. J., Kent, W. J., Lieb, J. D., Margulies, E. H., Myers, R. M., Stamatoyannopoulos, J. A., Tenenbaum, S. A., Weng, Z. P., White, K. P., Wold, B., Yu, Y., Wrobel, J., Risk, B. A., Gunawardena, H. P., Kuiper, H. C., Maier, C. W., Xie, L., Chen, X., Mikkelsen, T. S., Gillespie, S. (September 2012) An integrated encyclopedia of DNA elements in the human genome. Nature, 489 (7414). pp. 57-74. ISSN 0028-0836

Tessanne, K., Golding, M. C., Long, C. R., Peoples, M. D., Hannon, G., Westhusin, M. E. (March 2012) Production of transgenic calves expressing an shRNA targeting myostatin. Molecular Reproduction and Development, 79 (3). pp. 176-185. ISSN 1040452X (ISSN)

He, M., Liu, Y., Wang, X., Zhang, M. Q., Hannon, G. J., Huang, Z. J. (January 2012) Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain. Neuron, 73 (1). pp. 35-48. ISSN 1097-4199 (Electronic)0896-6273 (Linking)

Muerdter, F., Olovnikov, I., Molaro, A., Rozhkov, N. V., Czech, B., Gordon, A., Hannon, G. J., Aravin, A. A. (January 2012) Production of artificial piRNAs in flies and mice. RNA, 18 (1). pp. 42-52. ISSN 1355-8382

Van Stry, M., Oguin Iii, T. H., Cheloufi, S., Vogel, P., Watanabe, M., Pillai, M. R., Dash, P., Thomas, P. G., Hannon, G. J., Bix, M. (2012) Enhanced susceptibility of Ago1/3 double-null mice to influenza a virus infection. Journal of Virology, 86 (8). pp. 4151-4157. ISSN 0022538X (ISSN)

Bender, H. S., Murchison, E. P., Pickett, H. A., Deakin, J. E., Strong, M. A., Conlan, C., McMillan, D. A., Neumann, A. A., Greider, C. W., Hannon, G. J., Reddel, R. R., Graves, J. A. M. (2012) Extreme Telomere Length Dimorphism in the Tasmanian Devil and Related Marsupials Suggests Parental Control of Telomere Length. PLoS One, 7 (9). ISSN 19326203 (ISSN)

Fang, F., Hodges, E., Molaro, A., Dean, M., Hannon, G. J., Smith, A. D. (2012) Genomic landscape of human allele-specific DNA methylation. Proceedings of the National Academy of Sciences of the United States of America, 109 (19). pp. 7332-7337. ISSN 00278424 (ISSN)

Liu, S., Patel, S. H., Ginestier, C., Ibarra, I., Martin-Trevino, R., Bai, S., McDermott, S. P., Shang, L., Ke, J., Ou, S. J., Heath, A., Zhang, K. J., Korkaya, H., Clouthier, S. G., Charafe-Jauffret, E., Birnbaum, D., Hannon, G. J., Wicha, M. S. (2012) MicroRNA93 regulates proliferation and differentiation of normal and malignant breast stem cells. PLoS Genetics, 8 (6). ISSN 15537390 (ISSN)

Dahlman, K. B., Parker, J. S., Shamu, T., Hieronymus, H., Chapinski, C., Carver, B., Chang, K., Hannon, G. J., Sawyers, C. L. (2012) Modulators of prostate cancer cell proliferation and viability identified by short-hairpin RNA library screening. PLoS One, 7 (4). ISSN 19326203 (ISSN)

Chang, K., Marran, K., Valentine, A., Hannon, G. J. (2012) RNAi in cultured mammalian cells using synthetic siRNAs. Cold Spring Harbor Protocols, 7 (9). pp. 957-961. ISSN 19403402

Preall, J. B., Czech, B., Guzzardo, P. M., Muerdter, F., Hannon, G. J. (2012) Shutdown is a component of the Drosophila piRNA biogenesis machinery. RNA, 18 (8). pp. 1446-1457. ISSN 13558382 (ISSN)

Uren, P. J., Bahrami-Samani, E., Burns, S. C., Qiao, M., Karginov, F. V., Hodges, E., Hannon, G. J., Sanford, J. R., Penalva, L. O. F., Smith, A. D. (2012) Site identification in high-throughput RNA-protein interaction data. Bioinformatics, 28 (23). pp. 3013-3020. ISSN 13674803 (ISSN)

Tan, X., Lu, Z. J., Gao, G., Xu, Q., Hu, L., Fellmann, C., Li, M. Z., Qu, H., Lowe, S. W., Hannon, G. J., Elledge, S. J. (2012) Tiling genomes of pathogenic viruses identifies potent antiviral shRNAs and reveals a role for secondary structure in shRNA efficacy. Proceedings of the National Academy of Sciences of the United States of America, 109 (3). pp. 869-874. ISSN 00278424 (ISSN)

Lindsay, J., Carone, D. M., Brown, J., Hall, L., Qureshi, S., Mitchell, S. E., Jannetty, N., Hannon, G., Renfree, M., Pask, A., O'Neill, M., O'Neill, R. (2012) Unique small RNA signatures uncovered in the tammar wallaby genome. BMC Genomics, 13. p. 559. ISSN 1471-2164 (Electronic)1471-2164 (Linking)

Chi, S. W., Hannon, G. J., Darnell, R. B. (2012) An alternative mode of microRNA target recognition. Nature Structural and Molecular Biology, 19 (3). pp. 321-327. ISSN 15459993 (ISSN)

Dow, L. E., Premsrirut, P. K., Zuber, J., Fellmann, C., McJunkin, K., Miething, C., Park, Y., Dickins, R. A., Hannon, G. J., Lowe, S. W. (2012) A pipeline for the generation of shRNA transgenic mice. Nature Protocols, 7 (2). pp. 374-393. ISSN 17542189 (ISSN)

Ipsaro, J. J., Haase, A. D., Knott, S. R., Joshua-Tor, L., Hannon, G. J. (2012) The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature, 491 (7423). pp. 279-282. ISSN 00280836 (ISSN) (Public Dataset)

Elkayam, E., Kuhn, C. D., Tocilj, A., Haase, A. D., Greene, E. M., Hannon, G. J., Joshua-Tor, L. (2012) The structure of human argonaute-2 in complex with miR-20a. Cell, 150 (1). pp. 100-110. ISSN 00928674 (ISSN) (Public Dataset)

Liu-Sullivan, N., Zhang, J., Bakleh, A., Marchica, J., Li, J., Siolas, D., Laquerre, S., Degenhardt, Y. Y., Wooster, R., Chang, K., Hannon, G. J., Powers, S. (December 2011) Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1). Oncotarget, 2 (12). pp. 1254-64. ISSN 1949-2553 (Electronic) 1949-2553 (Linking)

Joshua-Tor, L., Hannon, G. J. (October 2011) Ancestral Roles of Small RNAs: An Ago-Centric Perspective. Cold Spring Harb Perspect Biol, 3 (10). ISSN 1943-0264 (Electronic)

Molaro, A., Hodges, E., Fang, F., Song, Q., McCombie, W. R., Hannon, G. J., Smith, A. D. (September 2011) Sperm Methylation Profiles Reveal Features of Epigenetic Inheritance and Evolution in Primates. Cell, 146 (6). pp. 1029-1041. ISSN 0092-8674 (Public Dataset)

Albert, F. W., Hodges, E., Jensen, J. D., Besnier, F., Xuan, Z. Y., Rooks, M., Bhattacharjee, A., Brizuela, L., Good, J. M., Green, R. E., Burbano, H. A., Plyusnina, I. Z., Trut, L., Andersson, L., Schoneberg, T., Carlborg, O., Hannon, G. J., Paabo, S. (September 2011) Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection. Heredity, 107 (3). pp. 205-214. ISSN 0018-067X

Rangan, P., Malone, Colin D. , Navarro, C., Newbold, S. P, Hayes, P. S, Sachidanandam, R., Hannon, G. J., Lehmann, R. (August 2011) piRNA Production Requires Heterochromatin Formation in Drosophila. Current Biology, 21 (16). pp. 1373-1379. ISSN 0960-9822

Erlich, Y., Edvardson, S., Hodges, E., Zenvirt, S., Thekkat, P., Shaag, A., Dor, T., Hannon, G. J., Elpeleg, O. (May 2011) Exome sequencing and disease-network analysis of a single family implicate a mutation in KIF1A in hereditary spastic paraparesis. Genome Research, 21 (5). pp. 658-664. ISSN 1088-9051

Myers, R. M., Stamatoyannopoulos, J., Snyder, M., Dunham, I., Hardison, R. C., Bernstein, B. E., Gingeras, T. R., Kent, W. J., Birney, E., Wold, B., Crawford, G. E., Epstein, C. B., Shoresh, N., Ernst, J., Mikkelsen, T. S., Kheradpour, P., Zhang, X. L., Wang, L., Issner, R., Coyne, M. J., Durham, T., Ku, M. C., Truong, T., Ward, L. D., Altshuler, R. C., Lin, M. F., Kellis, M., Davis, C. A., Kapranov, P., Dobin, A., Zaleski, C., Schlesinger, F., Batut, P., Chakrabortty, S., Jha, S., Lin, W., Drenkow, J., Wang, H. E., Bell, K. G., Gao, H., Bell, I., Dumais, E., Dumais, J., Antonarakis, S. E., Ucla, C., Borel, C., Guigo, R., Djebali, S., Lagarde, J., Kingswood, C., Ribeca, P., Sammeth, M., Alioto, T., Merkel, A., Tilgner, H., Carninci, P., Hayashizaki, Y., Lassmann, T., Takahashi, H., Abdelhamid, R. F., Hannon, G., Fejes-Toth, K., Preall, J., Gordon, A., Sotirova, V., Reymond, A., Howald, C., Graison, E. A. Y., Chrast, J., Ruan, Y. J., Ruan, X. A., Shahab, A., Poh, W. T., Wei, C. L., Furey, T. S., Boyle, A. P., Sheffield, N. C., Song, L. Y., Shibata, Y., Vales, T., Winter, D., Zhang, Z. C., London, D., Wang, T. Y., Keefe, D., Iyer, V. R., Lee, B. K., McDaniell, R. M., Liu, Z., Battenhouse, A., Bhinge, A. A., Lieb, J. D., Grasfeder, L. L., Showers, K. A., Giresi, P. G., Kim, S. K. C., Shestak, C., Pauli, F., Reddy, T. E., Gertz, J. (April 2011) A User's Guide to the Encyclopedia of DNA Elements (ENCODE). Plos Biology, 9 (4). ISSN 1544-9173 (Public Dataset)

Premsrirut, P. K., Dow, L. E., Kim, S. Y., Camiolo, M., Malone, C. D., Miething, C., Scuoppo, C. , Zuber, J., Dickins, R. A., Kogan, Scott C, Shroyer, Kenneth R, Sordella, R., Hannon, G. J., Lowe, S. W. (March 2011) A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference. Cell, 145 (1). pp. 145-158. ISSN 0092-8674

Lachke, S. A., Alkuraya, F. S., Kneeland, S. C., Ohn, T., Aboukhalil, A., Howell, G. R., Saadi, I., Cavallesco, R., Yue, Y. Z., Tsai, A. C. H., Nair, K. S., Cosma, M. I., Smith, R. S., Hodges, E., AlFadhli, S. M., Al-Hajeri, A., Shamseldin, H. E., Behbehani, A., Hannon, G. J., Bulyk, M. L., Drack, A. V., Anderson, P. J., John, S. W. M., Maas, R. L. (March 2011) Mutations in the RNA Granule Component TDRD7 Cause Cataract and Glaucoma. Science, 331 (6024). pp. 1571-1576. ISSN 0036-8075

Fellmann, C., Zuber, J., McJunkin, K., Chang, K. , Malone, C. D., Dickins, R. A., Xu, Q., Hengartner, M. O., Elledge, S. J., Hannon, G. J., Lowe, S. W. (March 2011) Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay. Molecular Cell, 41 (6). pp. 733-746. ISSN 1097-2765

Bivona, T. G., Hieronymus, H., Parker, J., Chang, K., Taron, M., Rosell, R., Moonsamy, P., Dahlman, K., Miller, V. A., Costa, C., Hannon, G. J., Sawyers, C. L. (March 2011) FAS and NF-kappa B signalling modulate dependence of lung cancers on mutant EGFR. Nature, 471 (7339). pp. 523-526. ISSN 0028-0836

Berezikov, E., Robine, N., Samsonova, A., Westholm, J. O., Naqvi, A., Hung, J. H., Okamura, K., Dai, Q., Bortolamiol-Becet, D., Martin, R., Zhao, Y. J., Zamore, P. D., Hannon, G. J., Marra, M. A., Weng, Z. P., Perrimon, N., Lai, E. C. (February 2011) Deep annotation of Drosophila melanogaster microRNAs yields insights into their processing, modification, and emergence. Genome Research, 21 (2). pp. 203-215. ISSN 1088-9051

Czech, B., Hannon, G. J. (January 2011) Small RNA sorting: matchmaking for Argonautes. Nat Rev Genet, 12 (1). pp. 19-31. ISSN 1471-0064 (Electronic) 1471-0056 (Linking)

Zuber, J., McJunkin, K., Fellmann, C., Dow, L. E., Taylor, M. J., Hannon, G. J., Lowe, S. W. (January 2011) Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNA. Nature Biotechnology, 29 (1). pp. 79-85.

Wang, J., Czech, B., Crunk, A., Wallace, A., Mitreva, M., Hannon, G. J., Davis, R. E. (2011) Deep small RNA sequencing from the nematode Ascaris reveals conservation, functional diversification, and novel developmental profiles. Genome Research, 21 (9). pp. 1462-1477. ISSN 10889051 (ISSN)

Hodges, E., Molaro, A., Dos Santos, C. O., Thekkat, P., Song, Q., Uren, P. J., Park, J. H., Butler, J., Rafii, S., McCombie, W. R., Smith, A. D., Hannon, G. J. (2011) Directional DNA Methylation Changes and Complex Intermediate States Accompany Lineage Specificity in the Adult Hematopoietic Compartment. Molecular Cell, 44 (1). pp. 17-28. ISSN 1097-2765

Lee, S., Paulson, K. G., Murchison, E. P., Afanasiev, O. K., Alkan, C., Leonard, J. H., Byrd, D. R., Hannon, G. J., Nghiem, P. (2011) Identification and validation of a novel mature microRNA encoded by the Merkel cell polyomavirus in human Merkel cell carcinomas. Journal of Clinical Virology, 52 (3). pp. 272-275. ISSN 13866532 (ISSN)

Choi, Y. J., Lin, C. P., Ho, J. J., He, X., Okada, N., Bu, P., Zhong, Y., Kim, S. Y., Bennett, M. J., Chen, C., Ozturk, A., Hicks, G. G., Hannon, G. J., He, L. (2011) MiR-34 miRNAs provide a barrier for somatic cell reprogramming. Nature Cell Biology, 13 (11). pp. 1353-1360. ISSN 14657392 (ISSN)

Spierings, D. C., McGoldrick, D., Hamilton-Easton, A. M., Neale, G., Murchison, E. P., Hannon, G. J., Green, D. R., Withoff, S. (2011) Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage. Blood, 117 (20). pp. 5340-5349. ISSN 00064971 (ISSN)

Obad, S., Dos Santos, C. O., Petri, A., Heidenblad, M., Broom, O., Ruse, C., Fu, C., Lindow, M., Stenvang, J., Straarup, E. M., Hansen, H. F., Koch, T., Pappin, D., Hannon, G. J., Kauppinen, S. (2011) Silencing of microRNA families by seed-targeting tiny LNAs. Nature Genetics, 43 (4). pp. 371-380. ISSN 10614036 (ISSN)

Tanaka, T., Hosokawa, M., Vagin, V. V., Reuter, M., Hayashi, E., Mochizuki, A. L., Kitamura, K., Yamanaka, H., Kondoh, G., Okawa, K., Kuramochi-Miyagawa, S., Nakano, T., Sachidanandam, R., Hannon, G. J., Pillai, R. S., Nakatsuji, N., Chuma, S. (2011) Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis. Proceedings of the National Academy of Sciences of the United States of America, 108 (26). pp. 10579-10584. ISSN 00278424 (ISSN)

Zamparini, A. L., Davis, M. Y., Malone, C. D., Vieira, E., Zavadil, J., Sachidanandam, R., Hannon, G. J., Lehmann, R. (2011) Vreteno, a gonad-specific protein, is essential for germline development and primary pirna biogenesis in Drosophila. Development, 138 (18). pp. 4039-4050. ISSN 09501991 (ISSN)

Ni, J. Q., Zhou, R., Czech, B., Liu, L. P., Holderbaum, L., Yang-Zhou, D., Shim, H. S., Tao, R., Handler, D., Karpowicz, P., Binari, R., Booker, M., Brennecke, J., Perkins, L. A., Hannon, G. J., Perrimon, N. (2011) A genome-scale shRNA resource for transgenic RNAi in Drosophila. Nature Methods, 8 (5). pp. 405-407. ISSN 15487091 (ISSN)

Haase, A. D., Fenoglio, S., Muerdter, F., Guzzardo, P. M., Czech, B., Pappin, D. J., Chen, C., Gordon, A., Hannon, G. J. (October 2010) Probing the initiation and effector phases of the somatic piRNA pathway in Drosophila. Genes and Development, 24 (22). pp. 2499-2504. ISSN 08909369 (ISSN)

Chong, M. M. W., Zhang, G. A., Cheloufi, S., Neubert, T. A., Hannon, G. J., Littman, D. R. (September 2010) Canonical and alternate functions of the microRNA biogenesis machinery. Genes & Development, 24 (17). pp. 1951-1960. ISSN 0890-9369

Rozhkov, N. V., Aravin, A. A., Zelentsova, E. S., Schostak, N. G., Sachidanandam, R., McCombie, W. R., Hannon, G. J., Evgen'ev, M. B. (August 2010) Small RNA-based silencing strategies for transposons in the process of invading Drosophila species. RNA, 16 (8). pp. 1634-1645. ISSN 1355-8382

Karginov, F. V., Cheloufi, S., Chong, M. M. W., Stark, A., Smith, A. D., Hannon, G. J. (June 2010) Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend upon MicroRNAs, Drosha, and Additional Nucleases. Molecular Cell, 38 (6). pp. 781-788. ISSN 1097-2765

Cifuentes, D., Xue, H. L., Taylor, D. W., Patnode, H., Mishima, Y., Cheloufi, S., Ma, E. B., Mane, S., Hannon, G. J., Lawson, N. D., Wolfe, S. A., Giraldez, A. J. (June 2010) A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity. Science, 328 (5986). pp. 1694-1698. ISSN 0036-8075

Cheloufi, S., Dos Santos, C. O., Chong, M. M. W., Hannon, G. J. (June 2010) A Dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature, 465 (7298). 584-U76. ISSN 0028-0836

Malone, C. D., Hannon, G. J. (May 2010) Molecular Evolution of piRNA and Transposon Control Pathways in Drosophila. Cold Spring Harb Symp Quant Biol. pp. 225-234. ISSN 1943-4456 (Electronic) 0091-7451 (Linking)

Burbano, H. A., Hodges, E., Green, R. E., Briggs, A. W., Krause, J., Meyer, M., Good, J. M., Maricic, T., Johnson, P. L. F., Xuan, Z. Y., Rooks, M., Bhattacharjee, A., Brizuela, L., Albert, F. W., De La Rasilla, M., Fortea, J., Rosas, A., Lachmann, M., Hannon, G. J., Paabo, S. (May 2010) Targeted investigation of the neandertal genome by array-based sequence capture. Science, 328 (5979). pp. 723-725.

Rozhkov, N. V., Aravin, A. A., Sachidanandam, R., Hannon, G. J., Sokolova, O. N., Zelentsova, E. S., Shostak, N. G., Evgen'ev, M. B. (April 2010) The RNA interference system differently responds to the same mobile element in distant Drosophila species. Doklady Biochemistry and Biophysics, 431 (1). pp. 79-81. ISSN 1607-6729

Teta, M., Choi, Y., Andl, T., Murchison, E. P., Nagy, A., Hannon, G. J., Millar, S. E. (April 2010) Dicer is required in adult skin for maintenance of rapidly proliferating hair follicle matrix cells, hair shaft formation, and catagen. Journal of Investigative Dermatology, 130 (S1). S106. ISSN 0022-202X

Choi, Y., Nagy, A., Tam, O. H., Hannon, G. J., Millar, S. E. (April 2010) The miRNA-processing enzyme Drosha is required for hair follicle regression, hair shaft differentiation, long-term maintenance of hair follicle stem cells, and epidermal homeostasis. Journal of Investigative Dermatology, 130 (S1). S108. ISSN 0022-202X

Christodoulou, F., Raible, F., Tomer, R., Simakov, O., Trachana, K., Klaus, S., Snyman, H., Hannon, G. J., Bork, P., Arendt, D. (February 2010) Ancient animal microRNAs and the evolution of tissue identity. Nature, 463 (7284). pp. 1084-1088. ISSN 0028-0836

Erlich, Y., Gordon, A., Brand, M., Hannon, G. J., Mitra, P. P. (February 2010) Compressed genotyping. IEEE Transactions on Information Theory, 56 (2). pp. 706-723.

Edvardson, S., Shaag, A., Zenvirt, S., Erlich, Y., Hannon, G. J., Shanske, A. L., Gomori, J. M., Ekstein, J., Elpeleg, O. (January 2010) Joubert Syndrome 2 (JBTS2) in Ashkenazi Jews Is Associated with a TMEM216 Mutation. American Journal of Human Genetics, 86 (1). pp. 93-97.

Karginov, F. V., Hannon, G. J. (January 2010) The CRISPR System: Small RNA-Guided Defense in Bacteria and Archaea. Molecular Cell, 37 (1). pp. 7-19.

Murchison, E. P., Tovar, C., Hsu, A., Bender, H. S., Kheradpour, P., Rebbeck, C. A., Obendorf, D., Conlan, C., Bahlo, M., Blizzard, C. A., Pyecroft, S., Kreiss, A., Kellis, M., Stark, A., Harkins, T. T., Marshall Graves, J. A., Woods, G. M., Hannon, G. J., Papenfuss, A. T. (January 2010) The Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer. Science, 327 (5961). pp. 84-7. ISSN 1095-9203 (Electronic) 1095-9203 (Linking)

Berezikov, E., Liu, N., Flynt, A. S., Hodges, E., Rooks, M., Hannon, G. J., Lai, E. C. (January 2010) Evolutionary flux of canonical microRNAs and mirtrons in Drosophila. Nature Genetics, 42 (1). pp. 6-9. ISSN 1061-4036

Rosa-Rosa, J. M., Gracia-Aznarez, F. J., Hodges, E., Pita, G., Rooks, M., Xuan, Z., Bhattacharjee, A., Brizuela, L., Silva, J. M., Hannon, G. J., Benitez, J. (2010) Deep sequencing of target linkage assay-identified regions in familial breast cancer: methods, analysis pipeline and troubleshooting. PLoS One, 5 (4). e9976. ISSN 1932-6203

Igartua, C., Turner, E. H., Ng, S. B., Hodges, E., Hannon, G. J., Bhattacharjee, A., Rieder, M. J., Nickerson, D. A., Shendure, J. (2010) Targeted enrichment of specific regions in the human genome by array hybridization. Current Protocols in Human Genetics (SUPPL.). 18.3.1-18.3.14. ISSN 19348266 (ISSN)

Olive, V., Bennett, M. J., Walker, J. C., Ma, C., Jiang, I., Cordon-Cardo, C., Li, Q. J., Lowe, S. W., Hannon, G. J., He, L. (December 2009) miR-19 is a key oncogenic component of mir-17-92. Genes & Development, 23 (24). pp. 2839-2849. ISSN 0890-9369

Aravin, A. A., van der Heijden, G. W., Castaneda, J., Vagin, V. V., Hannon, G. J., Bortvin, A. (December 2009) Cytoplasmic Compartmentalization of the Fetal piRNA Pathway in Mice. Plos Genetics, 5 (12). e1000764. ISSN 1553-7390

Smith, A. D., Chung, W. Y., Hodges, E., Kendall, Jude T., Hannon, G. J., Hicks, J. B., Xuan, Z., Zhang, M. Q. (November 2009) Updates to the RMAP short-read mapping software. Bioinformatics, 25 (21). pp. 2841-2842.

Bric, A., Miething, C., Bialucha, C. U., Scuoppo, C., Zender, L., Krasnitz, A., Xuan, Z., Zuber, J., Wigler, M. H., Hicks, J. B., McCombie, W. R., Hemann, M. T., Hannon, G. J., Powers, S., Lowe, S. W. (October 2009) Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model. Cancer Cell, 16 (4). pp. 324-35. ISSN 1535-6108

Erlich, Yaniv, Gordon, Assaf, Brand, Michael, Hannon, Gregory J, Mitra, Partha P (September 2009) Compressed Genotyping. IEEE Transactions on Information Theory. (Submitted)

Hodges, E., Smith, A. D., Kendall, J. T., Xuan, Z., Ravi, K., Rooks, M., Zhang, M. Q., Ye, K., Bhattacharjee, A., Brizuela, L., McCombie, W. R., Wigler, M. H., Hannon, G. J., Hicks, J. B. (September 2009) High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Genome Research, 19 (9). pp. 1593-1605. ISSN 1088-9051

Hodges, E., Rooks, M., Xuan, Z., Bhattacharjee, A., Gordon, D. B., Brizuela, L., McCombie, W. R., Hannon, G. J. (May 2009) Hybrid selection of discrete genomic intervals on custom-designed microarrays for massively parallel sequencing. Nature Protocols, 4 (6). pp. 960-974. ISSN 1754-2189

Malone, C. D., Brennecke, J., Dus, M., Stark, A., McCombie, W. R., Sachidanandam, R., Hannon, G. J. (May 2009) Specialized piRNA Pathways Act in Germline and Somatic Tissues of the Drosophila Ovary. Cell, 137 (3). 522-535 . ISSN 0092-8674

Premsrirut, P. K., Miething, C., Zuber, J., Yong, K. S., Hannon, G. J., Lowe, S. W. (March 2009) Conditional Regulation of Tumor Suppressor Genes in Vivo Using Rna Interference. Journal of Investigative Medicine, 57 (3). ISSN 1081-5589

Ezhkova, E., Pasolli, H. A., Parker, J. S., Stokes, N., Su, I. H., Hannon, G. J., Tarakhovsky, A., Fuchs, E. (March 2009) Ezh2 Orchestrates Gene Expression for the Stepwise Differentiation of Tissue-Specific Stem Cells. Cell, 136 (6). pp. 1122-1135. ISSN 0092-8674

Uziel, T., Karginov, F. V., Xie, S. Q., Parker, J. S., Wang, Y. D., Gajjar, A., He, L., Ellison, D., Gilbertson, R. J., Hannon, G. J., Roussel, M. F. (February 2009) The miR-17 similar to 92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma. Proceedings of the National Academy of Sciences of the United States of America, 106 (8). pp. 2812-2817. ISSN 0027-8424

Malone, C. D., Hannon, G. J. (February 2009) Small RNAs as Guardians of the Genome. Cell, 136 (4). pp. 656-668. ISSN 0092-8674

Fejes-Toth, K., Sotirova, V., Sachidanandam, R., Assaf, G., Hannon, G. J., Kapranov, P., Foissac, S., Willingham, A. T., Duttagupta, R., Dumais, E., Gingeras, T. R. (February 2009) Post-transcriptional processing generates a diversity of 5'-modified long and short RNAs. Nature, 457 (7232). pp. 1028-1032. ISSN 0028-0836

Vagin, V. V., Hannon, G. J., Aravin, A. A. (2009) Arginine methylation as a molecular signature of the Piwi small RNA pathway. Cell Cycle, 8 (24). pp. 4003-4004. ISSN 15384101 (ISSN)

Rechavi, O., Erlich, Y., Amram, H., Flomenblit, L., Karginov, F. V., Goldstein, I., Hannon, G. J., Kloog, Y. (2009) Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs. Genes and Development, 23 (16). pp. 1971-1979. ISSN 08909369 (ISSN)

Silva, J. M., Ezhkova, E., Silva, J., Heart, S., Castillo, M., Campos, Y., Castro, V., Bonilla, F., Cordon-Cardo, C., Muthuswamy, S. K., Powers, S., Fuchs, E., Hannon, G. J. (2009) Cyfip1 Is a Putative Invasion Suppressor in Epithelial Cancers. Cell, 137 (6). pp. 1047-1061. ISSN 00928674 (ISSN)

Erlich, Y., Chang, K., Gordon, A., Ronen, R., Navon, O., Rooks, M., Hannon, G. J. (2009) DNA Sudoku - Harnessing high-throughput sequencing for multiplexed specimen analysis. Genome Research, 19 (7). pp. 1243-1253. ISSN 10889051 (ISSN)

Xu, Q., Schlabach, M. R., Hannon, G. J., Elledge, S. J. (2009) Design of 240,000 orthogonal 25mer DNA barcode probes. Proceedings of the National Academy of Sciences of the United States of America, 106 (7). pp. 2289-2294. ISSN 00278424 (ISSN)

Tessanne, K., Stroud, T., Long, C., Hannon, G. J., Sadeghieh, S., Hwang, E., Chen, S., Polejaeva, I., Westhusin, M. (2009) Development of Transgenic Livestock with Reduced Myostatin Expression Using Rna Interference. Reproduction Fertility and Development, 21 (1). p. 251. ISSN 1031-3613

Czech, B., Zhou, R., Erlich, Y., Brennecke, J., Binari, R., Villalta, C., Gordon, A., Perrimon, N., Hannon, G. J. (2009) Hierarchical Rules for Argonaute Loading in Drosophila. Molecular Cell, 36 (3). pp. 445-456. ISSN 10972765 (ISSN)

Peoples, M., Sadeghieh, S., Hwang, E., Chen, S., Hannon, G. J., Long, C., Westhusin, M. (2009) Inhibition of Foot and Mouth Disease Virus in Vitro Using Rna Interference. Reproduction Fertility and Development, 21 (1). p. 103. ISSN 1031-3613

Fabian, M. R., Mathonnet, G., Sundermeier, T., Mathys, H., Zipprich, J. T., Svitkin, Y. V., Rivas, F., Jinek, M., Wohlschlegel, J., Doudna, J. A., Chen, C. Y. A., Shyu, A. B., Yates Iii, J. R., Hannon, G. J., Filipowicz, W., Duchaine, T. F., Sonenberg, N. (2009) Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation. Molecular Cell, 35 (6). pp. 868-880. ISSN 10972765 (ISSN)

Zhou, R., Czech, B., Brennecke, J., Sachidanandam, R., Wohlschlegel, J. A., Perrimon, N., Hannon, G. J. (2009) Processing of Drosophila endo-siRNAs depends on a specific Loquacious isoform. RNA, 15 (10). pp. 1886-1895. ISSN 13558382 (ISSN)

Vagin, V. V., Wohlschlegel, J., Qu, J., Jonsson, Z., Huang, X., Chuma, S., Girard, A., Sachidanandam, R., Hannon, G. J., Aravin, A. A. (2009) Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members. Genes and Development, 23 (15). pp. 1749-1762. ISSN 08909369 (ISSN)

Couvillion, M. T., Lee, S. R., Hogstad, B., Malone, C. D., Tonkin, L. A., Sachidanandam, R., Hannon, G. J., Collins, K. (2009) Sequence, biogenesis, and function of diverse small RNA classes bound to the Piwi family proteins of Tetrahymena thermophila. Genes and Development, 23 (17). pp. 2016-2032. ISSN 08909369 (ISSN)

Castellano, L., Giamas, G., Jacob, J., Coombes, R. C., Lucchesi, W., Thiruchelvam, P., Barton, G., Jiao, L. R., Wait, R., Waxman, J., Hannon, G. J., Stebbing, J. (2009) The estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response. Proceedings of the National Academy of Sciences of the United States of America, 106 (37). pp. 15732-15737. ISSN 00278424 (ISSN)

Zender, L., Xue, W., Zuber, J., Semighini, C. P., Krasnitz, A., Ma, B., Zender, P., Kubicka, S., Luk, J. M., Schirmacher, P., McCombie, W. R., Wigler, M. H., Hicks, J. B., Hannon, G. J., Powers, S., Lowe, S. W. (November 2008) An Oncogenomics-Based In Vivo RNAi Screen Identifies Tumor Suppressors in Liver Cancer. Cell, 135 (5). pp. 852-864. ISSN 0092-8674

Brennecke, J., Malone, C. D., Aravin, A. A., Sachidanandam, R., Stark, A., Hannon, G. J. (November 2008) An epigenetic role for maternally inherited piRNAs in transposon silencing. Science, 322 (5906). pp. 1387-92.

Erlich, Y., Mitra, P. P., Delabastide, M., McCombie, W. R., Hannon, G. J. (August 2008) Alta-Cyclic: a self-optimizing base caller for next-generation sequencing. Nature Methods, 5 (8). 679 - 682.

Teta, M., Thomas, A., Okegbe, T., Murchison, E. P., Nagy, A., Hannon, G. J., Millar, S. E. (July 2008) Dicer is required for maintenance of hair follicle stem cells in adult skin. Developmental Biology, 319 (2). p. 556. ISSN 0012-1606

Burgess, D. J., Doles, J., Zender, L., Xue, W., Ma, B., McCombie, W. R., Hannon, G. J., Lowe, S. W., Hemann, M. T. (July 2008) Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc Natl Acad Sci U S A, 105 (25). pp. 9053-9058.

Murchison, E. P., Kheradpour, P., Sachidanandam, R., Smith, C., Hodges, E., Xuan, Z., Kellis, M., Grutzner, F., Stark, A., Hannon, G. J. (June 2008) Conservation of small RNA pathways in platypus. Genome Research, 18 (6). pp. 995-1004. ISSN 1088-9051

Tworkowski, K. A., Chakraborty, A. A., Samuelson, A. V., Seger, Y. R., Narita, M., Hannon, G. J., Lowe, S. W., Tansey, W. P. (April 2008) Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc. Proc Natl Acad Sci U S A, 105 (16). pp. 6103-6108.

Mi, S. J., Cai, T., Hu, Y. G., Chen, Y., Hodges, E., Ni, F. R., Wu, L., Li, S., Zhou, H., Long, C. Z., Chen, S., Hannon, G. J., Qi, Y. J. (April 2008) Sorting of small RNAs into Arabidopsis argonaute complexes is directed by the 5' terminal nucleotide. Cell, 133 (1). pp. 116-127. ISSN 0092-8674

Teta, M., Andl, T., Okegbe, T., Murchison, E. P., Nagy, A., Hannon, G. J., Millar, S. E. (April 2008) Global changes in mRNA levels and failure of hair follicle stem cell maintenance in adult Dicer-deleted skin. Journal of Investigative Dermatology, 128 (Suppl.). S154-S154. ISSN 0022-202X

Benetti, R., Gonzalo, S., Jaco, I., Munoz, P., Gonzalez, S., Schoeftner, S., Murchison, E. P., Andl, T., Chen, T. P., Klatt, P., Li, E., Serrano, M., Millar, S., Hannon, G. J., Blasco, M. A. (March 2008) A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nature Structural & Molecular Biology, 15 (3). pp. 268-279. ISSN 1545-998515459993 (ISSN)

Silva, J. M., Marran, K., Parker, J. S., Silva, J., Golding, M., Schlabach, M. R., Elledge, S. J., Hannon, G. J., Chang, K. (February 2008) Profiling essential genes in human mammary cells by multiplex RNAi screening. Science, 319 (5863). pp. 617-20.

Schlabach, M. R., Luo, J., Solimini, N. L., Hu, G., Xu, Q. K., Li, M. Z., Zhao, Z. M., Smogorzewska, A., Sowa, M. E., Ang, X. L. L., Westbrook, T. F., Liang, A. C., Chang, K., Hackett, J. A., Harper, J. W., Hannon, G. J., Elledge, S. J. (February 2008) Cancer proliferation gene discovery through functional Genomics. Science, 319 (5863). pp. 620-624. ISSN 0036-8075

Chen, J. F., Murchison, E. P., Tang, R., Callis, T. E., Tatsuguchi, M., Deng, Z., Rojas, M., Hammond, S. M., Schneider, M. D., Selzman, C. H., Meissner, G., Patterson, C., Hannon, G. J., Wang, D. Z. (February 2008) Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A, 105 (6). pp. 2111-2116. ISSN 0027-8424

Olson, A. J., Brennecke, J., Aravin, A. A., Hannon, G. J., Sachidanandam, R. (2008) Analysis of large-scale sequencing of small RNAs. Pacific Symposium on Biocomputing. pp. 126-136. ISSN 17935091 (ISSN)

Du, J., Jablonski, S., Yen, T. J., Hannon, G. J. (2008) Astrin regulates Aurora-A localization. Biochem Biophys Res Commun, 370 (2). pp. 213-9.

Zhou, R., Hotta, I., Denli, A. M., Hong, P., Perrimon, N., Hannon, G. J. (2008) Comparative Analysis of Argonaute-Dependent Small RNA Pathways in Drosophila. Molecular Cell, 32 (4). pp. 592-599. ISSN 10972765 (ISSN)

Girard, A., Hannon, G. J. (2008) Conserved themes in small-RNA-mediated transposon control. Trends Cell Biol, 18 (3). pp. 136-148.

Haiser, H. J., Karginov, F. V., Hannon, G. J., Elliot, M. A. (2008) Developmentally regulated cleavage of tRNAs in the bacterium Streptomyces coelicolor. Nucleic Acids Research, 36 (3). pp. 732-741. ISSN 03051048 (ISSN)

Tyler, D. M., Okamura, K., Chung, W. J., Hagen, J. W., Berezikov, E., Hannon, G. J., Lai, E. C. (2008) Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci. Genes and Development, 22 (1). pp. 26-36. ISSN 08909369 (ISSN)

Warren, W. C., Hillier, L. W., Marshall Graves, J. A., Birney, E., Ponting, C. P., Grützner, F., Belov, K., Miller, W., Clarke, L., Chinwalla, A. T., Yang, S. P., Heger, A., Locke, D. P., Miethke, P., Waters, P. D., Veyrunes, F., Fulton, L., Fulton, B., Graves, T., Wallis, J., Puente, X. S., López-Otín, C., Ordóñez, G. R., Eichler, E. E., Chen, L., Cheng, Z., Deakin, J. E., Alsop, A., Thompson, K., Kirby, P., Papenfuss, A. T., Wakefield, M. J., Olender, T., Lancet, D., Huttley, G. A., Smit, A. F. A., Pask, A., Temple-Smith, P., Batzer, M. A., Walker, J. A., Konkel, M. K., Harris, R. S., Whittington, C. M., Wong, E. S. W., Gemmell, N. J., Buschiazzo, E., Vargas Jentzsch, I. M., Merkel, A., Schmitz, J., Zemann, A., Churakov, G., Ole Kriegs, J., Brosius, J., Murchison, E. P., Sachidanandam, R., Smith, C., Hannon, G. J., Tsend-Ayush, E., McMillan, D., Attenborough, R., Rens, W., Ferguson-Smith, M., Lefèvre, C. M., Sharp, J. A., Nicholas, K. R., Ray, D. A., Kube, M., Reinhardt, R., Pringle, T. H., Taylor, J., Jones, R. C., Nixon, B., Dacheux, J. L., Niwa, H., Sekita, Y., Huang, X., Stark, A., Kheradpour, P., Kellis, M., Flicek, P., Chen, Y., Webber, C., Hardison, R., Nelson, J., Hallsworth-Pepin, K., Delehaunty, K., Markovic, C., Minx, P., Feng, Y., Kremitzki, C., Mitreva, M., Glasscock, J., Wylie, T., Wohldmann, P., Thiru, P., Nhan, M. N., Pohl, C. S., Smith, S. M., Hou, S., Renfree, M. B. (2008) Genome analysis of the platypus reveals unique signatures of evolution. Nature, 453 (7192). pp. 175-183. ISSN 00280836 (ISSN)

Tam, O. H., Aravin, A. A., Stein, P., Girard, A., Murchison, E. P., Cheloufi, S., Hodges, E., Anger, M., Sachidanandam, R., Schultz, R. M., Hannon, G. J. (2008) Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes. Nature, 453 (7194). pp. 534-538. ISSN 00280836 (ISSN)

Aravin, A. A., Hannon, G. J. (2008) Small RNA silencing pathways in germ and stem cells. Cold Spring Harb Symp Quant Biol, 73. pp. 283-90. ISSN 1943-4456 (Electronic)0091-7451 (Linking)

Czech, B., Malone, C. D., Zhou, R., Stark, A., Schlingeheyde, C., Dus, M., Perrimon, N., Kellis, M., Wohlschlegel, J. A., Sachidanandam, R., Hannon, G. J., Brennecke, J. (2008) An endogenous small interfering RNA pathway in Drosophila. Nature, 453 (7196). pp. 798-802. ISSN 0028-0836

De Pietri Tonelli, D., Pulvers, J. N., Haffner, C., Murchison, E. P., Hannon, G. J., Huttner, W. B. (2008) miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex. Development, 135 (23). pp. 3911-3921. ISSN 09501991 (ISSN)

Aravin, A. A., Sachidanandam, R., Bourc'his, D., Schaefer, C., Pezic, D., Toth, K. F., Bestor, T., Hannon, G. J. (2008) A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice. Molecular Cell, 31 (6). pp. 785-799. ISSN 10972765 (ISSN)

Ibarra, I., Erlich, Y., Muthuswamy, S. K., Sachidanandam, R., Hannon, Gregory J. (December 2007) A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. Genes Dev, 21 (24). pp. 3238-43. ISSN 0890-9369 (Print)

Karginov, F. V., Conaco, C., Xuan, Z. Y., Schmidt, B. H., Parker, J. S., Mandel, G., Hannon, G. J. (December 2007) A biochemical approach to identifying microRNA targets. Proceedings of the National Academy of Sciences of the United States of America, 104 (49). pp. 19291-6. ISSN 0027-8424

Stark, A., Kheradpour, P., Parts, L., Brennecke, J., Hodges, E., Hannon, G. J., Kellis, M. (November 2007) Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes. Genome Res, 17 (12). pp. 1865-1879.

Hodges, E., Xuan, Z. Y., Balija, V., Kramer, M. R., Molla, M. N., Smith, S. W., Middle, C. M., Rodesch, M. J., Albert, T. J., Hannon, G. J., McCombie, W. R. (November 2007) Genome-wide in situ exon capture for selective resequencing. Nature Genetics, 39 (12). pp. 1522-7. ISSN 1061-4036

Aravin, A. A., Hannon, G. J., Brennecke, J. (November 2007) The Piwi-piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race. Science, 318 (5851). pp. 761-764. ISSN 1095-9203 (Electronic)

Stark, A., Lin, M. F., Kheradpour, P., Pedersen, J. S., Parts, L., Carlson, J. W., Crosby, M. A., Rasmussen, M. D., Roy, S., Deoras, A. N., Ruby, J. G., Brennecke, J., Hodges, E., Hinrichs, A. S., Caspi, A., Park, S. W., Han, M. V., Maeder, M. L., Polansky, B. J., Robson, B. E., Aerts, S., van Helden, J., Hassan, B., Gilbert, D. G., Eastman, D. A., Rice, M., Weir, M., Hahn, M. W., Park, Y., Dewey, C. N., Pachter, L., Kent, W. J., Haussler, D., Lai, E. C., Bartel, D. P., Hannon, G. J., Kaufman, T. C., Eisen, M. B., Clark, A. G., Smith, D., Celniker, S. E., Gelbart, W. M., Kellis, M. (November 2007) Discovery of functional elements in 12 Drosophila genomes using evolutionary signatures. Nature, 450 (7167). pp. 219-232. ISSN 0028-0836

He, L., He, X., Lowe, S. W., Hannon, G. J. (November 2007) microRNAs join the p53 network - another piece in the tumour-suppression puzzle. Nat Rev Cancer, 7 (11). pp. 819-822. ISSN 1474-1768 (Electronic)

Kim, J., Inoue, K., Ishii, J., Vanti, W. B., Voronov, S. V., Murchison, E., Hannon, G. J., Abeliovich, A. (August 2007) A MicroRNA feedback circuit in midbrain dopamine neurons. Science, 317 (5842). pp. 1220-4. ISSN 1095-9203 (Electronic) 1095-9203 (Linking)

Dickins, R. A., McJunkin, K., Hernando, E., Premsrirut, P. K., Krizhanovsky, V., Burgess, D. J., Kim, S. Y., Cordon-Cardo, C., Zender, L., Hannon, G. J., Lowe, S. W. (July 2007) Tissue-specific and reversible RNA interference in transgenic mice. Nat Genet, 39 (7). 914 - 921. ISSN 1061-4036 (Print)

He, L., He, X., Lim, L. P., De Stanchina, E., Xuan, Z., Liang, Y., Xue, W., Zender, L., Magnus, J., Ridzon, D., Jackson, A. L., Linsley, P. S., Chen, C., Lowe, S. W., Cleary, M. A., Hannon, G. J. (June 2007) A microRNA component of the p53 tumour suppressor network. Nature, 447 (7148). pp. 1130-4. ISSN 1476-4687 (Electronic)

Aravin, A. A., Sachidanandam, R., Girard, A., Fejes-Toth, K., Hannon, G. J. (May 2007) Developmentally regulated piRNA clusters implicate MILI in transposon control. Science, 316 (5825). pp. 744-7. ISSN 1095-9203 (Electronic)

Zhao, T., Li, G. L., Mi, S. J., Li, S., Hannon, G. J., Wang, X. J., Qi, Y. J. (May 2007) A complex system of small RNAs in the unicellular green alga Chlamydomonas reinhardtii. Genes Dev, 21 (10). pp. 1190-1203. ISSN 0890-9369

Draviam, V. M., Stegmeier, F., Nalepa, G., Sowa, M. E., Chen, J., Liang, A., Hannon, G. J., Sorger, P. K., Harper, J. W., Elledge, S. J. (May 2007) A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling. Nature Cell Biology, 9 (5). pp. 556-564. ISSN 1465-7392

Stegmeier, F., Rape, M., Draviam, V. M., Nalepa, G., Sowa, M. E., Ang, X. L. L., McDonald, E. R., Li, M. Z., Hannon, G. J., Sorger, P. K., Kirschner, M. W., Harper, J. W., Elledge, S. J. (April 2007) Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities. Nature, 446 (7138). pp. 876-881. ISSN 0028-0836

Carmell, M. A., Girard, A., van de Kant, H. J. G., Bourc'his, D., Bestor, T. H., de Rooij, D. G., Hannon, G. J. (April 2007) MIWI2 Is Essential for Spermatogenesis and Repression of Transposons in the Mouse Male Germline. Developmental Cell, 12 (4). pp. 503-514.

Houwing, S., Kamminga, L. M., Berezikov, E., Cronembold, D., Girard, A., van den Elst, H., Filippov, D. V., Blaser, H., Raz, E., Moens, C. B., Plasterk, R. H. A., Hannon, G. J., Draper, B. W., Ketting, R. F. (April 2007) A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in zebrafish. Cell, 129 (1). pp. 69-82. ISSN 0092-8674

Brennecke, J., Aravin, A. A., Stark, A., Dus, M., Kellis, M., Sachidanandam, R., Hannon, G. J. (March 2007) Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell, 128 (6). pp. 1089-103. ISSN 0092-8674 (Print)

Murchison, E. P., Stein, P., Xuan, Z. Y., Pan, H., Zhang, M. Q., Schultz, R. M., Hannon, G. J. (March 2007) Critical roles for Dicer in the female germline. Genes Dev, 21 (6). pp. 682-93. ISSN 0890-9369 (Print)

Girard, A., Hannon, G. J. (March 2007) [The role of piRNAs in mouse spermatogenesis.]. J Soc Biol, 201 (4). pp. 411-8.

Stegh, A. H., Kim, H., Bachoo, R. M., Forloney, K. L., Zhang, J., Schulze, H., Park, K., Hannon, G. J., Yuan, J. Y., Louis, D. N., DePinho, R. A., Chin, L. (January 2007) Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma. Genes Dev, 21 (1). pp. 98-111. ISSN 0890-9369

He, X., He, L., Hannon, G. J. (2007) The guardian's little helper: MicroRNAs in the p53 tumor suppressor network. Cancer Research, 67 (23). pp. 11099-11101. ISSN 00085472 (ISSN)

Qi, Y., He, X., Wang, X. J., Kohany, O., Jurka, J., Hannon, G. J. (October 2006) Distinct catalytic and non-catalytic roles of ARGONAUTE4 in RNA-directed DNA methylation. Nature, 443 (7114). pp. 1008-12. ISSN 1476-4687 (Electronic)

Chang, K., Elledge, S. J., Hannon, G. J. (September 2006) Lessons from Nature: microRNA-based shRNA libraries. Nat Methods, 3 (9). pp. 707-14. ISSN 1548-7091 (Print)

Zender, L., Spector, M. S., Xue, W., Flemming, P., Cordon-Cardo, C., Silke, J., Fan, S. T., Luk, J. M., Wigler, M. H., Hannon, G. J., Mu, D., Lucito, R., Powers, S., Lowe, S. W. (June 2006) Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell, 125 (7). pp. 1253-67. ISSN 0092-8674 (Print)

Andl, T., Murchison, E. P., Liu, Fei, Zhang, Yi, Yunta-Gonzalez, M., Tobias, J. W., Andl, C. D., Seykora, J. T., Hannon, G. J., Millar, S. E. (May 2006) The miRNA-Processing Enzyme Dicer Is Essential for the Morphogenesis and Maintenance of Hair Follicles. Current Biology, 16 (10). pp. 1041-1049. ISSN 09609822

Golding, M. C., Long, C. R., Carmell, M. A., Hannon, G. J., Westhusin, M. E. (April 2006) Suppression of prion protein in livestock by RNA interference. Proc Natl Acad Sci U S A, 103 (14). pp. 5285-90. ISSN 0027-8424 (Print)

Mason, D. X., Keppler, D., Zhang, J., Jackson, T. J., Seger, Y. R., Matsui, S., Abreo, F., Cowell, J. K., Hannon, G. J., Lowe, S. W., Lin, A. W. (February 2006) Defined genetic events associated with the spontaneous in vitro transformation of ElA/Ras-expressing human IMR90 fibroblasts. Carcinogenesis, 27 (2). pp. 350-359. ISSN 0143-3334 (Print)

Olson, A., Sheth, N., Lee, J. S., Hannon, G. J., Sachidanandam, R. (January 2006) RNAi Codex: a portal/database for short-hairpin RNA (shRNA) gene-silencing constructs. Nucleic Acids Res, 34 (Databa). D153-7. ISSN 1362-4962 (Electronic)

Valencia-Sanchez, M. A., Liu, J., Hannon, G. J., Parker, R. (2006) Control of translation and mRNA degradation by miRNAs and siRNAs. Genes and Development, 20 (5). pp. 515-524. ISSN 08909369

Hannon, G. J., Rivas, F. V., Murchison, E. P., Steitz, J. A. (2006) The Expanding Universe of Noncoding RNAs. Cold Spring Harb Symp Quant Biol, 71. pp. 551-564. ISSN 1943-4456 (Electronic) 0091-7451 (Linking)

Dickins, R. A., Premsrirut, P., McJunkin, K., Kim, S. Y., Hannon, G. J., Lowe, S. W. (2006) Tetracycline-regulated p53 knockdown in cells and transgenic mice. Toxicologic Pathology, 34 (7). p. 1006. ISSN 0192-6233

Girard, A., Sachidanandam, R., Hannon, G. J., Carmell, M. A. (2006) A germline-specific class of small RNAs binds mammalian Piwi proteins. Nature, 442 (7099). pp. 199-202. ISSN 00280836

Liu, J. D., Rivas, F. V., Wohlschlegel, J., Yates, J. R., Parker, R., Hannon, G. J. (December 2005) A role for the P-body component GW182 in microRNA function. Nature Cell Biology, 7 (12). pp. 1261-1266. ISSN 1465-7392

Dickins, R. A., Hemann, M. T., Zilfou, J. T., Simpson, D. R., Ibarra, I., Hannon, G. J., Lowe, S. W. (November 2005) Probing tumor phenotypes using stable and regulated synthetic microRNA precursors. Nat Genet, 37 (11). pp. 1289-95. ISSN 1061-4036 (Print)

Silva, J. M., Li, M. Z., Chang, K., Ge, W., Golding, M. C., Rickles, R. J., Siolas, D., Hu, G., Paddison, P. J., Schlabach, M. R., Sheth, N., Bradshaw, J., Burchard, J., Kulkarni, A., Cavet, G., Sachidanandam, R., McCombie, W. R., Cleary, M. A., Elledge, S. J., Hannon, G. J. (November 2005) Second-generation shRNA libraries covering the mouse and human genomes. Nat Genet, 37 (11). pp. 1281-8.

Qi, Yijun, Hannon, Gregory J. (October 2005) Uncovering RNAi mechanisms in plants: biochemistry enters the foray. FEBS Lett, 579 (26). pp. 5899-903. ISSN 0014-5793 (Print)

Zender, L., Spector, M. S., Xue, W., Flemming, P., Mu, D., Cordon-Cardo, C., Powers, S., Hannon, G. J., Lucito, R., Lowe, S. W. (October 2005) Representational oligonucleotide microarray (ROMA) identifies cIAP1/cIAP2 as candidate oncogenes in mouse and human hepatocarcinogenesis-validation of cIAP1 as a therapeutic target in liver cancer in a new mouse model of hepatocellular carcinoma. Hepatology, 42 (4). 244A-244A. ISSN 0270-9139

Elledge, S. J., Hannon, G. J. (October 2005) An open letter to cancer researchers. Science, 310 (5747). 439-+. ISSN 0036-8075

Stegmeier, F., Hu, G., Rickles, R. J., Hannon, G. J., Elledge, S. J. (September 2005) A lentiviral microRNA-based system for single-copy polymerase II-regulated RNA interference in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 102 (37). pp. 13212-13217. ISSN 0027-8424

Murchison, E. P., Partridge, J. F., Tam, O. H., Cheloufi, S., Hannon, G. J. (August 2005) Characterization of Dicer-deficient murine embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America, 102 (34). pp. 12135-40. ISSN 0027-8424

Qi, Yijun, Denli, Ahmet M., Hannon, Gregory J. (August 2005) Biochemical specialization within Arabidopsis RNA silencing pathways. Mol Cell, 19 (3). pp. 421-8. ISSN 1097-2765 (Print)

Liu, J., Valencia-Sanchez, M. A., Hannon, G. J., Parker, R. (July 2005) MicroRNA-dependent localization of targeted mRNAs to mammalian P-bodies. Nature Cell Biology, 7 (7). pp. 719-23. ISSN 1465-7392

He, L., Thomson, J. M., Hemann, M. T., Hernando-Monge, E., Mu, D., Goodson, S., Powers, S., Cordon-Cardo, C., Lowe, S. W., Hannon, G. J., Hammond, S. M. (June 2005) A microRNA polycistron as a potential human oncogene. Nature, 435 (7043). pp. 828-33. ISSN 0028-0836

Schramke, V., Sheedy, D. M., Denli, A. M., Bonila, C., Ekwall, K., Hannon, G. J., Allshire, R. C. (June 2005) RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription. Nature, 435 (7046). pp. 1275-1279. ISSN 0028-0836

Westbrook, T. F., Martin, E. S., Schlabach, M. R., Leng, Y. M., Liang, A. C., Feng, B., Zhao, J. J., Roberts, T. M., Mandel, G., Hannon, G. J., DePinho, R. A., Chin, L., Elledge, S. J. (June 2005) A genetic screen for candidate tumor suppressors identifies REST. Cell, 121 (6). pp. 837-848. ISSN 0092-8674

Rivas, Fabiola V., Tolia, Nirja H., Song, Ji-Joon, Aragon, Juan P., Liu, Jidong, Hannon, Gregory J., Joshua-Tor, Leemor (April 2005) Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol, 12 (4). pp. 340-9. ISSN 1545-9993 (Print) (Public Dataset)

Elgin, S. C. R., Haynes, K., Brower-Toland, B., Gracheva, E., Hannon, G. J., Caudy, A. A. (March 2005) RNAi-dependent assembly of heterochromatin in Drosophila. Faseb Journal, 19 (5). A1720-A1720. ISSN 0892-6638

Olson, A., Sheth, N., Lee, J., Hannon, G. J., Sachidanandam, R. (March 2005) Rnai codex - a comprehensive RNAi resource. Briefings in Bioinformatics, 6 (1). pp. 104-106. ISSN 1467-5463

Siolas, D., Lerner, C., Burchard, J., Ge, W., Linsley, P. S., Paddison, P. J., Hannon, G. J., Cleary, M. A. (February 2005) Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol, 23 (2). pp. 227-31. ISSN 1087-0156 (Print)

Schramke, V., Sheedy, D. M., Denli, A. M., Bonila, C., Ekwall, K., Hannon, G. J., Allshire, R. C. (2005) Erratum (Retracted article): RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription (Nature (2005) 435 (1275-1279)). Nature, 437 (7061). p. 1057. ISSN 00280836 (ISSN)

Zender, L., Xue, W., Cordon-Cardo, C., Hannon, G. J., Lucito, R., Powers, S., Flemming, P., Spector, M. S., Lowe, S. W. (2005) Generation and Analysis of Genetically Defined Liver Carcinomas Derived from Bipotential Liver Progenitors. Cold Spring Harb Symp Quant Biol, 70 (1). pp. 251-261. ISSN 1943-4456 (Electronic) 0091-7451 (Linking)

Cleary, M. A., Kilian, K., Wang, Y., Bradshaw, J., Cavet, G., Ge, W., Kulkarni, A., Paddison, P. J., Chang, K., Sheth, N., Leproust, E., Coffey, E. M., Burchard, J., McCombie, W. R., Linsley, P., Hannon, G. J. (December 2004) Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis. Nat Methods, 1 (3). pp. 241-8.

Dike, S., Balija, V. S., Nascimento, L. U., Xuan, Z. Y., Ou, J., Zutavern, T., Palmer, L. E., Hannon, G. J., Zhang, M. Q., McCombie, W. R. (December 2004) The mouse genome: experimental examination of gene predictions and transcriptional start sites. Genome Res, 14 (12). pp. 2424-9. ISSN 1088-9051 (Print)

Denli, A. M., Tops, B. B., Plasterk, R. H., Ketting, R. F., Hannon, G. J. (November 2004) Processing of primary microRNAs by the Microprocessor complex. Nature, 432 (7014). pp. 231-5. ISSN 1476-4687 (Electronic)

Silva, J., Chang, K., Hannon, G. J., Rivas, F. V. (November 2004) RNA-interference-based functional genomics in mammalian cells: reverse genetics coming of age. Oncogene, 23 (51). pp. 8401-9. ISSN 0950-9232 (Print)

Paddison, P. J., Cleary, M., Silva, J. M., Chang, K., Sheth, N., Sachidanandam, R., Hannon, G. J. (November 2004) Cloning of short hairpin RNAs for gene knockdown in mammalian cells. Nat Methods, 1 (2). pp. 163-7. ISSN 1548-7091 (Print)

Hannon, G. J., Rossi, J. J. (September 2004) Unlocking the potential of the human genome with RNA interference. Nature, 431 (7006). pp. 371-8. ISSN 1476-4687 (Electronic)

Liu, J., Carmell, M. A., Rivas, F. V., Marsden, C. G., Thomson, J. M., Song, J. J., Hammond, S. M., Joshua-Tor, L., Hannon, G. J. (September 2004) Argonaute2 is the catalytic engine of mammalian RNAi. Science, 305 (5689). pp. 1437-41. ISSN 1095-9203 (Electronic)

Song, J. J., Smith, S. K., Hannon, G. J., Joshua-Tor, L. (September 2004) Crystal structure of argonaute and its implications for RISC slicer activity. Science, 305 (5689). pp. 1434-1437. ISSN 0036-8075 (Public Dataset)

He, L., Hannon, G. J. (August 2004) MicroRNAs: Small RNAs with a big role in gene regulation. Nature Reviews Genetics, 5 (8). pp. 522-532. ISSN 1471-0056

Hemann, M. T., Zilfou, J. T., Zhao, Z., Burgess, D. J., Hannon, G. J., Lowe, S. W. (June 2004) Suppression of tumorigenesis by the p53 target PUMA. Proc Natl Acad Sci U S A, 101 (25). pp. 9333-8. ISSN 0027-8424 (Print)

Du, J., Hannon, G. J. (June 2004) Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion. Proc Natl Acad Sci U S A, 101 (24). pp. 8975-80. ISSN 0027-8424 (Print)

Murchison, E. P., Hannon, G. J. (June 2004) miRNAs on the move: miRNA biogenesis and the RNAi machinery. Curr Opin Cell Biol, 16 (3). pp. 223-9. ISSN 0955-0674 (Print)

Svoboda, P., Stein, P., Anger, M., Bernstein, E., Hannon, G. J., Schultz, R. M. (May 2004) RNAi and expression of retrotransposons MuERV-L and IAP in preimplantation mouse embryos. Developmental Biology, 269 (1). pp. 276-285. ISSN 0012-1606

Silva, J. M., Mizuno, H., Brady, A., Lucito, R., Hannon, G. J. (April 2004) RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells. Proc Natl Acad Sci U S A, 101 (17). pp. 6548-52. ISSN 0027-8424 (Print)

Paddison, P. J., Silva, J. M., Conklin, D. S., Schlabach, M., Li, M., Aruleba, S., Balija, V., O'Shaughnessy, A., Gnoj, L., Scobie, K., Chang, K., Westbrook, T., Cleary, M., Sachidanandam, R., McCombie, W. R., Elledge, S. J., Hannon, G. J. (March 2004) A resource for large-scale RNA-interference-based screens in mammals. Nature, 428 (6981). pp. 427-31. ISSN 1476-4687 (Electronic)

Carmell, M. A., Hannon, G. J. (March 2004) RNase III enzymes and the initiation of gene silencing. Nat Struct Mol Biol, 11 (3). pp. 214-8. ISSN 1545-9993 (Print)

Gupta, S., Schoer, R. A., Egan, J. E., Hannon, G. J., Mittal, V. (February 2004) Inducible, reversible, and stable RNA interference in mammalian cells. Proc Natl Acad Sci U S A, 101 (7). pp. 1927-32. ISSN 0027-8424 (Print)

Caudy, A. A., Hannon, G. J. (2004) Induction and biochemical purification of RNA-induced silencing complex from Drosophila S2 cells. Methods Mol Biol, 265. pp. 59-72. ISSN 1064-3745 (Print)

Kan, J. L. C., Griffin, G., Hannon, G. J. (2004) Mining the genome with RNAi to select cancer drug targets. Drug Discovery Today: Therapeutic Strategies, 1 (4). pp. 397-401. ISSN 17406773 (ISSN)

Hannon, G. J., Conklin, D. S. (2004) RNA interference by short hairpin RNAs expressed in vertebrate cells. Methods Mol Biol, 257. pp. 255-66. ISSN 1940-6029 (Electronic)1064-3745 (Linking)

Song, J. J., Liu, J., Tolia, N. H., Schneiderman, J., Smith, S. K., Martienssen, R. A., Hannon, G. J., Joshua-Tor, L. (December 2003) The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol, 10 (12). pp. 1026-32. ISSN 1072-8368 (Print) (Public Dataset)

Narita, M., Nunez, S., Heard, E., Narita, M., Lin, A. W., Hearn, S. A., Spector, D. L., Hannon, G. J., Lowe, S. W. (June 2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell, 113 (6). pp. 703-716. ISSN 0092-8674

Hemann, M. T., Fridman, J. S., Zilfou, J. T., Hernando, E., Paddison, P. J., Cordon-Cardo, C., Hannon, G. J., Lowe, S. W. (March 2003) An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nature Genetics, 33 (3). pp. 396-400. ISSN 1061-4036

Bernstein, E., Kim, S. Y., Carmell, M. A., Murchison, E. P., Alcorn, H., Li, M. Z., Mills, A. A., Elledge, S. J., Anderson, K. V., Hannon, G. J. (2003) Dicer is essential for mouse development. Nature Genetics, 35 (3). pp. 215-217. ISSN 10614036 (ISSN)

Silva, J. M., Sachidanandam, R., Hannon, G. J. (2003) Free energy lights the path toward more effective RNAi. Nature Genetics, 35 (4). pp. 303-305. ISSN 10614036 (ISSN)

Carmell, M. A., Zhang, L., Conklin, D. S., Hannon, G. J., Rosenquist, T. A. (2003) Germline transmission of RNAi in mice. Nature Structural Biology, 10 (2). pp. 91-92. ISSN 10728368 (ISSN)

Denli, A. M., Hannon, G. J. (2003) RNAi: An ever-growing puzzle. Trends in Biochemical Sciences, 28 (4). pp. 196-201. ISSN 09680004 (ISSN)

Palmer, L. E., O'Shaughnessy, A. L., Preston, R. R., Santos, L., Balija, V. S., Nascimento, L. U., Zutavern, T. L., Henthorn, P. S., Hannon, G. J., McCombie, W. R. (2003) A Survey of Canine Expressed Sequence Tags and a Display of Their Annotations Through a Flexible Web-Based Interface. Journal of Heredity, 94 (1). pp. 15-22. ISSN 00221503 (ISSN)

Caudy, A. A., Ketting, R. F., Hammond, S. M., Denli, A. M., Bathoorn, A. M. P., Tops, B. B. J., Silva, J. M., Myers, M. M., Hannon, G. J., Plasterk, R. H. A. (2003) A micrococcal nuclease homologue in RNAi effector complexes. Nature, 425 (6956). pp. 411-414. ISSN 00280836 (ISSN)

Paddison, P. J., Hannon, G. J. (2003) siRNAs and shRNAs: Skeleton keys to the human genome. Current Opinion in Molecular Therapeutics, 5 (3). pp. 217-224. ISSN 14648431 (ISSN)

McCaffrey, A. P., Meuse, L., Pham, T. T. T., Conklin, D. S., Hannon, G. J., Kay, M. A. (July 2002) Gene expression - RNA interference in adult mice. Nature, 418 (6893). pp. 38-39. ISSN 0028-0836

Carmell, M. A., Xuan, Z., Zhang, M. Q., Hannon, G. J. (2002) The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes and Development, 16 (21). pp. 2733-2742. ISSN 08909369 (ISSN)

Caudy, A. A., Myers, M., Hannon, G. J., Hammond, S. M. (2002) Fragile X-related protein and VIG associate with the RNA interference machinery. Genes and Development, 16 (19). pp. 2491-2496. ISSN 08909369 (ISSN)

Hannon, G. (2002) Mechanisms and application of RNA interference. Biology of Reproduction, 66. p. 70. ISSN 0006-3363

Ferbeyre, G., De Stanchina, E., Lin, A. W., Querido, E., McCurrach, M. E., Hannon, G. J., Lowe, S. W. (2002) Oncogenic ras and p53 cooperate to induce cellular senescence. Molecular and Cellular Biology, 22 (10). pp. 3497-3508. ISSN 02707306 (ISSN)

Hannon, G. J. (2002) RNA interference. Nature, 418 (6894). pp. 244-251. ISSN 00280836 (ISSN)

Silva, J. M., Hammond, S. M., Hannon, G. J. (2002) RNA interference: A promising approach to antiviral therapy? Trends in Molecular Medicine, 8 (11). pp. 505-508. ISSN 14714914 (ISSN)

Paddison, P. J., Hannon, G. J. (2002) RNA interference: The new somatic cell genetics? Cancer Cell, 2 (1). pp. 17-23. ISSN 15356108 (ISSN)

Paddison, P. J., Caudy, A. A., Bernstein, E., Hannon, G. J., Conklin, D. S. (2002) Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes and Development, 16 (8). pp. 948-958. ISSN 08909369 (ISSN)

Paddison, P. J., Caudy, A. A., Hannon, G. J. (2002) Stable suppression of gene expression by RNAi in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 99 (3). pp. 1443-1448. ISSN 00278424 (ISSN)

Seger, Y. R., García-Cao, M., Piccinin, S., Lo Cunsolo, C., Doglioni, C., Blasco, M. A., Hannon, G. J., Maestro, R. (2002) Transformation of normal human cells in the absence of telomerase activation. Cancer Cell, 2 (5). pp. 401-413. ISSN 15356108 (ISSN)

Du, J., Hannon, G. J. (2002) The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1. Nucleic Acids Research, 30 (24). pp. 5465-5475. ISSN 03051048 (ISSN)

Stolarov, J., Chang, K., Reiner, A., Rodgers, L., Hannon, G. J., Wigler, M. H., Mittal, V. (November 2001) Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America, 98 (23). pp. 13043-13048. ISSN 0027-8424

Ketting, R. F., Fischer, S. E. J., Bernstein, E., Sijen, T., Hannon, G. J., Plasterk, R. H. A. (October 2001) Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes and Development, 15 (20). pp. 2654-2659. ISSN 0890-9369

Hammond, S. M., Boettcher, S., Caudy, A. A., Kobayashi, R., Hannon, G. J. (August 2001) Argonaute2, a link between genetic and biochemical analyses of RNAi. Science, 293 (5532). pp. 1146-1150. ISSN 0036-8075

Hammond, S. M., Caudy, A. A., Hannon, G. J. (2001) Post-transcriptional gene silencing by double-stranded RNA. Nature Reviews Genetics, 2 (2). pp. 110-119. ISSN 14710056 (ISSN)

Bernstein, E., Caudy, A. A., Hammond, S. M., Hannon, G. J. (2001) Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature, 409 (6818). pp. 363-366. ISSN 00280836 (ISSN)

Bernstein, E., Denli, A. M., Hannon, G. J. (2001) The rest is silence. RNA, 7 (11). pp. 1509-1521. ISSN 13558382 (ISSN)

Wang, J., Hannon, G. J., Beach, D. H. (June 2000) Risky immortalization by telomerase. Nature, 405 (6788). pp. 755-756. ISSN 0028-0836

Carnero, A., Hudson, J. D., Hannon, G. J., Beach, D. H. (2000) Loss-of-function genetics in mammalian cells: The p53 tumor suppressor model. Nucleic Acids Research, 28 (11). pp. 2234-2241. ISSN 03051048 (ISSN)

Hammond, S. M., Bernstein, E., Beach, D., Hannon, G. J. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, 404 (6775). pp. 293-296. ISSN 00280836 (ISSN)

Wang, J., Hannon, G. J., Beach, D. H. (2000) Risky immortalization by telomerase. Nature, 405 (6788). pp. 755-756. ISSN 00280836 (ISSN)

Maestro, R., Dei Tos, A. P., Hamamori, Y., Krasnokutsky, S., Sartorelli, V., Kedes, L., Doglioni, C., Beach, D. H., Hannon, G. J. (September 1999) Twist is a potential oncogene that inhibits apoptosis. Genes and Development, 13 (17). pp. 2207-17. ISSN 0890-9369

Hannon, G. J., Sun, P., Carnero, A., Xie, L. Y., Maestro, R., Conklin, D. S., Beach, D. (February 1999) MaRX: an approach to genetics in mammalian cells. Science, 283 (5405). pp. 1129-30. ISSN 0036-8075

Hudson, J. D., Shoaibi, M. A., Maestro, R., Carnero, A., Hannon, G. J., Beach, D. H. (1999) A proinflammatory cytokine inhibits p53 tumor suppressor activity. Journal of Experimental Medicine, 190 (10). pp. 1375-1382. ISSN 00221007 (ISSN)

Sun, P., Dong, P., Dai, K., Hannon, G. J., Beach, D. (December 1998) p53-independent role of MDM2 in TGF-beta1 resistance. Science, 282 (5397). pp. 2270-2. ISSN 0036-8075 (Print)

LaMontagne, K. R., Hannon, G., Tonks, N. K. (November 1998) Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells. Proceedings of the National Academy of Sciences of the United States of America, 95 (24). pp. 14094-14099. ISSN 0027-8424

Carnero, A., Hannon, G. J. (1998) The INK4 family of CDK inhibitors. Current Topics in Microbiology and Immunology, 227. pp. 43-55. ISSN 0070-217X (Print)

Wang, J., Xie, L. Y., Allan, S., Beach, D., Hannon, G. J. (1998) Myc activates telomerase. Genes and Development, 12 (12). pp. 1769-1774. ISSN 08909369 (ISSN)

Fearnhead, H. O., Rodriguez, J., Govek, E. E., Guo, W., Kobayashi, R., Hannon, G., Lazebnik, Y. A. (1998) Oncogene-dependent apoptosis is mediated by caspase-9. Proc Natl Acad Sci U S A, 95 (23). pp. 13664-13669. ISSN 0027-8424

Alcorta, D. A., Xiong, Y., Phelps, D., Hannon, G., Beach, D., Barrett, J. C. (November 1996) Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 13742-13747. ISSN 00278424 (ISSN)

Balbín, M., Hannon, G. J., Pendás, A. M., Ferrando, A. A., Vizoso, F., Fueyo, A., López-Otín, C. (1996) Functional analysis of a p21(WAF1,CIP1,SDI1) mutant (Arg 94 → Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases. Journal of Biological Chemistry, 271 (26). pp. 15782-15786. ISSN 00219258 (ISSN)

Zhou, X., Suzuki, H., Lei, J., Cole, K., Yin, J., Suzuki, Y., Abraham, J. M., Shimada, Y., Imamura, M., Chan, T., Hannon, G. J., Meltzer, S. J. (1996) Growth suppression of esophageal cancer cells by p16 INK4 and p15 INK4B in vitro. Cancer Journal from Scientific American, 2 (4). pp. 221-224. ISSN 10814442 (ISSN)

Terry, L. A., Boyd, J., Alcorta, D., Lyon, T., Solomon, G., Hannon, G., Berchuck, A., Beach, D., Barrett, J. C. (1996) Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines. Molecular Carcinogenesis, 16 (4). pp. 221-228. ISSN 08991987 (ISSN)

Xie, Q., Sanz-Burgos, A. P., Hannon, G. J., Gutiérrez, C. (1996) Plant cells contain a novel member of the retinoblastoma family of growth regulatory proteins. EMBO Journal, 15 (18). pp. 4900-4908. ISSN 02614189 (ISSN)

Li, Rong, Hannon, G. J., Beach, D., Stillman, B. (1996) Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage. Current Biology, 6 (2). pp. 189-199. ISSN 09609822 (ISSN)

Demetrick, D. J., Matsumoto, S., Hannon, G. J., Okamoto, K., Xiong, Y., Zhang, H., Beach, D. H. (1995) Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3). Cytogenetics and Cell Genetics, 69 (3-4). pp. 190-192. ISSN 03010171 (ISSN)

Quelle, D. E., Ashmun, R. A., Hannon, G. J., Rehberger, P. A., Trono, D., Richter, K. H., Walker, C., Beach, D., Sherr, C. J., Serrano, M. (1995) Cloning and characterization of murine p16(INK4a) and p15(INK4b) genes. Oncogene, 11 (4). pp. 635-645. ISSN 09509232 (ISSN)

Halevy, O., Novitch, B. G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., Beach, D., Lassar, A. B. (1995) Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science, 267 (5200). pp. 1018-1021. ISSN 00368075 (ISSN)

Orlow, I., Lacombe, L., Hannon, G. J., Serrano, M., Pellicer, I., Dalbagni, G., Reuter, V. E., Zhang, Z. F., Beach, D., Cordon-Cardo, C. (1995) Deletion of the p16 and p15 genes in human bladder tumors. Journal of the National Cancer Institute, 87 (20). pp. 1524-1529. ISSN 00278874 (ISSN)

Suzuki, H., Zhou, X., Yin, J., Lei, J., Jiang, H. Y., Suzuki, Y., Chan, T., Hannon, G. J., Mergner, W. J., Abraham, J. M., Meltzer, S. J. (1995) Intragenic mutations of CDKN2B and CDKN2A in primary human esophageal cancers. Human Molecular Genetics, 4 (10). pp. 1883-1887. ISSN 09646906 (ISSN)

Ranade, K., Hussussian, C. J., Sikorski, R. S., Varmus, H. E., Goldstein, A. M., Tucker, M. A., Serrano, M., Hannon, G. J., Beach, D., Dracopoli, N. C. (1995) Mutations associated with familial melanoma impair p16(INK4) function. Nature Genetics, 10 (1). pp. 114-116. ISSN 10614036 (ISSN)

Okamoto, A., Hussain, S. P., Hagiwara, K., Spillare, E. A., Rusin, M. R., Demetrick, D. J., Serrano, M., Hannon, G. J., Shiseki, M., Zariwala, M., Xiong, Y., Beach, D. H., Yokota, J., Harris, C. C. (1995) Mutations in the p16(INK4)/MTS1/CDKN2, p15(INK4B)/MTS2, and p18 genes in primary and metastatic lung cancer. Cancer Research, 55 (7). pp. 1448-1451. ISSN 00085472 (ISSN)

Bruarolas, J., Chandrasekaran, C., Gordon, J. I., Beach, D., Jacks, T., Hannon, G. J. (1995) Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature, 377 (6549). pp. 552-557. ISSN 00280836 (ISSN)

Macleod, K. F., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B., Jacks, T. (1995) p53-Dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes and Development, 9 (8). pp. 935-944. ISSN 08909369

Beach, D., Serrano, M., Hannon, G. J. (February 1994) P16(Ink4) - an Specific Inhibitor of the Cdk4/Cyclin-D Kinase. Journal of Cellular Biochemistry, Supp (18C). p. 161. ISSN 0730-2312

Feilotter, H. E., Hannon, G. J., Ruddell, C. J., Beach, D. (1994) Construction of an improved host strain for two hybrid screening. Nucleic Acids Research, 22 (8). pp. 1502-1503. ISSN 03051048 (ISSN)

Li, R., Waga, S., Hannon, G. J., Beach, D., Stillman, B. (1994) Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. Nature, 371 (6497). pp. 534-537. ISSN 00280836 (ISSN)

Hannon, G. J., Casso, D., Beach, D. (1994) KAP: A dual specificity phosphatase that interacts with cyclin-dependent kinases. Proceedings of the National Academy of Sciences of the United States of America, 91 (5). pp. 1731-1735. ISSN 00278424 (ISSN)

Hannon, G. E., Hannon, G. J., Maroney, P. A., Nilsen, T. W. (1994) Transcription of a nematode U1 small nuclear RNA in vitro. 3'-end formation requires cis-acting elements within the coding sequence. Journal of Biological Chemistry, 269 (17). pp. 12387-12390. ISSN 00219258 (ISSN)

Hannon, G. J., Beach, D. (1994) p15(INK4B) is a potential effector of TGF-β-induced cell cycle arrest. Nature, 371 (6494). pp. 257-261. ISSN 00280836 (ISSN)

Waga, S., Hannon, G. J., Beach, D., Stillman, B. (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature, 369 (6481). pp. 574-578. ISSN 00280836 (ISSN)

Zhang, H., Hannon, G. J., Casso, D., Beach, D. (1994) p21 is a component of active cell cycle kinases. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 21-29. ISSN 00917451 (ISSN)

Zhang, H., Hannon, G. J., Beach, D. (1994) p21-Containing cyclin kinases exist in both active and inactive states. Genes and Development, 8 (15). pp. 1750-1758. ISSN 08909369 (ISSN)

Hannon, G. J., Demetrick, D., Beach, D. (1993) Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes and Development, 7 (12 A). pp. 2378-2391. ISSN 08909369 (ISSN)

Serrano, M., Hannon, G. J., Beach, D. (1993) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature, 366 (6456). pp. 704-707. ISSN 00280836 (ISSN)

Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., Beach, D. (1993) p21 is a universal inhibitor of cyclin kinases. Nature, 366 (6456). pp. 701-704. ISSN 00280836 (ISSN)

Hannon, G. J., Maroney, P. A., Yu, Y. T., Hannon, G. E., Nilsen, T. W. (1992) Interaction of U6 snRNA with a sequence required for function of the nematode SL RNA in trans-splicing. Science, 258 (5089). pp. 1775-1780. ISSN 00368075 (ISSN)

Maroney, P. A., Hannon, G. J., Shambaugh, J. D., Nilsen, T. W. (1991) Intramolecular base pairing between the nematode spliced leader and its 5' splice site is not essential for trans-splicing in vitro. EMBO Journal, 10 (12). pp. 3869-3875. ISSN 02614189 (ISSN)

Hannon, G. J., Chubb, A., Maroney, P. A., Hannon, G., Altman, S., Nilsen, T. W. (1991) Multiple cis-acting elements are required for RNA polymerase III transcription of the gene encoding H1 RNA, the RNA component of human RNase P. Journal of Biological Chemistry, 266 (34). pp. 22796-22799. ISSN 00219258 (ISSN)

Hannon, G. J., Maroney, P. A., Nilsen, T. W. (1991) U small nuclear ribonucleoprotein requirements for nematode cis- and trans-splicing in vitro. Journal of Biological Chemistry, 266 (34). pp. 22792-22695. ISSN 00219258 (ISSN)

Hannon, G. J., Maroney, P. A., Denker, J. A., Nilsen, T. W. (1990) Trans splicing of nematode pre-messenger RNA in vitro. Cell, 61 (7). pp. 1247-1255. ISSN 00928674 (ISSN)

Maroney, P. A., Hannon, G. J., Nilsen, T. W. (1990) Transcription and cap trimethylation of a nematode spliced leader RNA in a cell-free system. Proceedings of the National Academy of Sciences of the United States of America, 87 (2). pp. 709-713. ISSN 00278424 (ISSN)

Hannon, G. J., Maroney, P. A., Ayers, D. G., Shambaugh, J. D., Nilsen, T. W. (1990) Transcription of a nematode trans-spliced leader RNA require internal elements for both initiation and 3' end-formation. EMBO Journal, 9 (6). pp. 1915-1921. ISSN 02614189 (ISSN)

Maroney, P. A., Hannon, G. J., Denker, J. A., Nilsen, T. W. (1990) The nematode spliced leader RNA participates in trans-splicing as an Sm snRNP. Embo Journal, 9 (11). pp. 3667-3673. ISSN 0261-4189

Hannon, G. J., Maroney, P. A., Branch, A., Benenfield, B. J., Robertson, H. D., Nilsen, T. W. (October 1989) Accurate processing of human pre-rRNA in vitro. Molecular and Cellular Biology, 9 (10). pp. 4422-4431. ISSN 02707306 (ISSN)

Maroney, P. A., Hannon, G. J., Nilsen, T. W. (July 1989) Accurate and efficient RNA polymerase III transcription in a cell-free extract prepared from Ascaris suum embryos. Molecular and Biochemical Parasitology, 35 (3). pp. 277-283. ISSN 01666851

Ransohoff, R. M., Denker, J. A., Takacs, A. M., Hannon, G. J., Nilsen, T. W. (May 1989) Organization and expression of 5S rRNA genes in the parasitic nematode,Brugia malayi. Nucleic Acids Research, 17 (10). pp. 3773-3782. ISSN 03051048

Hannon, G. J., Jentoft, J. E. (1985) MOLECULAR DESIGNER: An interactive program for the display of protein structure on the IBM-PC. Computer Applications in the Biosciences, 1 (3). pp. 177-181. ISSN 02667061 (ISSN)

Book Section

Carmell, M. A., Hannon, G. J. (2004) Achieving stable, heritable gene silencing in the mouse. In: RNA interference (RNAI) : the nuts & bolts of sirna technology. The Nuts & Bolts series . DNA Press, Eagleville, PA , pp. 217-234. ISBN 0966402782

Paddison, Patrick J., Hannon, Gregory J. (2004) RNA Interference in Mammals: Journey to the Center of Human Disease. In: Molecular Cancer Therapeutics. John Wiley & Sons, Inc., Hoboken, NJ, pp. 55-72. ISBN 9780471656166

Paddison, P. J., Caudy, A. A., Sachidanandam, R., Hannon, G. J. (2004) Short hairpin activated gene silencing in mammalian cells. In: RNA Interference, Editing and Modification: methods and protocols. Methods Mol Biol, 265 . Springer, pp. 85-100.

Hannon, Gregory J., Zamore, Phillip D. (2003) Small RNAs, big biology: biochemical studies of RNA interference. In: RNAi: a guide to gene silencing. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N. Y., pp. 87-108. ISBN 978-087969641-2

Hannon, G. J. (1995) Expression of cell cycle proteins using recombinant baculoviruses. In: Cell Cycle: Materials and Methods. Springer-Verlag, Berlin, pp. 231-242.

Conference or Workshop Item

Watson, Philip A, Lawrence, Kayla E, Nadkarni, Tejasveeta V, Ishmael, Taslima F, Lee, Eugine, Rivera, Aura C Agudelo, Love, Jillian R, Wongvipat, John, Cai, Ling, Nazir, Abbas, Iaquinta, Phillip J, Chang, Kenneth, Liang, Yupu, Hannon, Greg J, Sawyers, Charles L (August 2020) The protein phosphatase 4 complex is a tumor suppressor in prostate cancer. In: AACR Annual Meeting.

Cheloufi, Sihem, Hannon, Gregory J. (June 2007) Investigating the role of the argonautes during mouse embryogenesis. In: Developmental Biology.

Book

Hannon, G. J., ed. (2003) RNAi: a guide to gene silencing. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.. ISBN 978-087969704-4

Zhu, Li, Hannon, Gregory J., eds. (2000) Yeast hybrid technologies. BioTechniques . Eaton Publishing, Natick, MA.

Video

Hannon, G. J. (November 2012) Talk from Greg Hannon at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)