Items where Community is "Cancer Genetics and Genomics Program"

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Paper

Gao, Yuan, Vakoc, Christopher R (February 2024) Therapeutic index of targeting select chromatin complexes in human cancer patients. Current Opinion in Genetics and Development, 85. p. 102162. ISSN 0959-437X

He, Xue-Yan, Gao, Yuan, Ng, David, Michalopoulou, Evdokia, George, Shanu, Adrover, Jose M, Sun, Lijuan, Albrengues, Jean, Daßler-Plenker, Juliane, Han, Xiao, Wan, Ledong, Wu, Xiaoli Sky, Shui, Longling S, Huang, Yu-Han, Liu, Bodu, Su, Chang, Spector, David L, Vakoc, Christopher R, Van Aelst, Linda, Egeblad, Mikala (February 2024) Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment. Cancer Cell. ISSN 1535-6108

Loh, Liyen, Carcy, Salomé, Krovi, Harsha S, Domenico, Joanne, Spengler, Andrea, Lin, Yong, Torres, Joshua, Palmer, William, Norman, Paul J, Stone, Matthew, Brunetti, Tonya, Meyer, Hannah V, Gapin, Laurent (December 2023) Unraveling the Phenotypic States of Human innate-like T Cells: Comparative Insights with Conventional T Cells and Mouse Models. bioRxiv. (Submitted)

Maia-Silva, Diogo, Schier, Allison C, Skopelitis, Damianos, Kechejian, Vahag, Alpsoy, Aktan, Liverpool, Jynelle, Taatjes, Dylan J, Vakoc, Christopher R (October 2023) Marker-based CRISPR screening reveals a MED12-p63 interaction that activates basal identity in pancreatic ductal adenocarcinoma. bioRxiv. (Submitted)

Sroka, Martyna W, Skopelitis, Damianos, Vermunt, Marit W, Preall, Jonathan B, El Demerdash, Osama, de Almeida, Larissa MN, Chang, Kenneth, Utama, Raditya, Gryder, Berkley, Caligiuri, Giuseppina, Ren, Diqiu, Nalbant, Benan, Milazzo, Joseph P, Tuveson, David A, Dobin, Alexander, Hiebert, Scott W, Stengel, Kristy R, Mantovani, Roberto, Khan, Javed, Kohli, Rahul M, Shi, Junwei, Blobel, Gerd A, Vakoc, Christopher R (September 2023) Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of USA, 120 (36). e2303859120. ISSN 0027-8424 (Public Dataset)

Scheben, Armin, Mendivil Ramos, Olivia, Kramer, Melissa, Goodwin, Sara, Oppenheim, Sara, Becker, Daniel J, Schatz, Michael C, Simmons, Nancy B, Siepel, Adam, McCombie, W Richard (September 2023) Long-Read Sequencing Reveals Rapid Evolution of Immunity- and Cancer-Related Genes in Bats. Genome Biology and Evolution, 15 (9). ISSN 1759-6653 (Public Dataset)

Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E, Kleeman, Sam O, Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Gao, Qing, Flint, Thomas R, Young, Lisa, Connell, Claire M, Lukey, Michael J, Goncalves, Marcus D, White, Eileen P, Venkitaraman, Ashok R, Janowitz, Tobias (July 2023) Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia. Cell Metabolism, 35 (7). 1147-1162.e7. ISSN 1550-4131

Schwörer, Simon, Cimino, Francesco V, Ros, Manon, Tsanov, Kaloyan M, Ng, Charles, Lowe, Scott W, Carmona-Fontaine, Carlos, Thompson, Craig B (May 2023) Hypoxia Potentiates the Inflammatory Fibroblast Phenotype Promoted by Pancreatic Cancer Cell-Derived Cytokines. Cancer Research, 83 (10). pp. 1596-1610. ISSN 0008-5472

Ferrer, Miriam, Anthony, Tracy G, Ayres, Janelle S, Biffi, Giulia, Brown, Justin C, Caan, Bette J, Cespedes Feliciano, Elizabeth M, Coll, Anthony P, Dunne, Richard F, Goncalves, Marcus D, Grethlein, Jonas, Heymsfield, Steven B, Hui, Sheng, Jamal-Hanjani, Mariam, Lam, Jie Min, Lewis, David Y, McCandlish, David, Mustian, Karen M, O'Rahilly, Stephen, Perrimon, Norbert, White, Eileen P, Janowitz, Tobias (April 2023) Cachexia: A systemic consequence of progressive, unresolved disease. Cell, 186 (9). pp. 1824-1845. ISSN 0092-8674

Fiskus, Warren, Mill, Christopher P, Birdwell, Christine, Davis, John A, Das, Kaberi, Boettcher, Steffen, Kadia, Tapan M, DiNardo, Courtney D, Takahashi, Koichi, Loghavi, Sanam, Soth, Michael J, Heffernan, Tim, McGeehan, Gerard M, Ruan, Xinjia, Su, Xiaoping, Vakoc, Christopher R, Daver, Naval, Bhalla, Kapil N (April 2023) Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1. Blood Cancer Journal, 13 (1). p. 53. ISSN 2044-5385 (Public Dataset)

Rozowsky, Joel, Gao, Jiahao, Borsari, Beatrice, Yang, Yucheng T, Galeev, Timur, Gürsoy, Gamze, Epstein, Charles B, Xiong, Kun, Xu, Jinrui, Li, Tianxiao, Liu, Jason, Yu, Keyang, Berthel, Ana, Chen, Zhanlin, Navarro, Fabio, Sun, Maxwell S, Wright, James, Chang, Justin, Cameron, Christopher JF, Shoresh, Noam, Gaskell, Elizabeth, Drenkow, Jorg, Adrian, Jessika, Aganezov, Sergey, Aguet, François, Balderrama-Gutierrez, Gabriela, Banskota, Samridhi, Corona, Guillermo Barreto, Chee, Sora, Chhetri, Surya B, Cortez Martins, Gabriel Conte, Danyko, Cassidy, Davis, Carrie A, Farid, Daniel, Farrell, Nina P, Gabdank, Idan, Gofin, Yoel, Gorkin, David U, Gu, Mengting, Hecht, Vivian, Hitz, Benjamin C, Issner, Robbyn, Jiang, Yunzhe, Kirsche, Melanie, Kong, Xiangmeng, Lam, Bonita R, Li, Shantao, Li, Bian, Li, Xiqi, Lin, Khine Zin, Luo, Ruibang, Mackiewicz, Mark, Meng, Ran, Moore, Jill E, Mudge, Jonathan, Nelson, Nicholas, Nusbaum, Chad, Popov, Ioann, Pratt, Henry E, Qiu, Yunjiang, Ramakrishnan, Srividya, Raymond, Joe, Salichos, Leonidas, Scavelli, Alexandra, Schreiber, Jacob M, Sedlazeck, Fritz J, See, Lei Hoon, Sherman, Rachel M, Shi, Xu, Shi, Minyi, Sloan, Cricket Alicia, Strattan, J Seth, Tan, Zhen, Tanaka, Forrest Y, Vlasova, Anna, Wang, Jun, Werner, Jonathan, Williams, Brian, Xu, Min, Yan, Chengfei, Yu, Lu, Zaleski, Christopher, Zhang, Jing, Ardlie, Kristin, Cherry, J Michael, Mendenhall, Eric M, Noble, William S, Weng, Zhiping, Levine, Morgan E, Dobin, Alexander, Wold, Barbara, Mortazavi, Ali, Ren, Bing, Gillis, Jesse, Myers, Richard M, Snyder, Michael P, Choudhary, Jyoti, Milosavljevic, Aleksandar, Schatz, Michael C, Bernstein, Bradley E, Guigó, Roderic, Gingeras, Thomas R, Gerstein, Mark (March 2023) The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models. Cell, 186 (7). 1493-1511.e40. ISSN 0092-8674

Gao, Yuan, He, Xue-Yan, Wu, Xiaoli S, Huang, Yu-Han, Toneyan, Shushan, Ha, Taehoon, Ipsaro, Jonathan J, Koo, Peter K, Joshua-Tor, Leemor, Bailey, Kelly M, Egeblad, Mikala, Vakoc, Christopher R (January 2023) ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation. Nature Cell Biology. ISSN 1465-7392 (Public Dataset)

Gladman, Nicholas, Goodwin, Sara, Chougule, Kapeel, Richard McCombie, William, Ware, Doreen (January 2023) Era of gapless plant genomes: innovations in sequencing and mapping technologies revolutionize genomics and breeding. Current Opinion in Biotechnology, 79. p. 102886. ISSN 0958-1669

Soto-Feliciano, Yadira M, Sánchez-Rivera, Francisco J, Perner, Florian, Barrows, Douglas W, Kastenhuber, Edward R, Ho, Yu-Jui, Carroll, Thomas, Xiong, Yijun, Anand, Disha, Soshnev, Alexey A, Gates, Leah, Beytagh, Mary Clare, Cheon, David, Gu, Shengqing, Liu, X Shirley, Krivtsov, Andrei V, Meneses, Maximiliano, de Stanchina, Elisa, Stone, Richard M, Armstrong, Scott A, Lowe, Scott W, Allis, C David (January 2023) A Molecular Switch between Mammalian MLL Complexes Dictates Response to Menin-MLL Inhibition. Cancer Discovery, 13 (1). pp. 146-169. ISSN 2159-8274

Mattick, John S, Amaral, Paulo P, Carninci, Piero, Carpenter, Susan, Chang, Howard Y, Chen, Ling-Ling, Chen, Runsheng, Dean, Caroline, Dinger, Marcel E, Fitzgerald, Katherine A, Gingeras, Thomas R, Guttman, Mitchell, Hirose, Tetsuro, Huarte, Maite, Johnson, Rory, Kanduri, Chandrasekhar, Kapranov, Philipp, Lawrence, Jeanne B, Lee, Jeannie T, Mendell, Joshua T, Mercer, Timothy R, Moore, Kathryn J, Nakagawa, Shinichi, Rinn, John L, Spector, David L, Ulitsky, Igor, Wan, Yue, Wilusz, Jeremy E, Wu, Mian (January 2023) Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews Molecular Cell Biology. ISSN 1471-0072

Sun, Xueqin, Klingbeil, Olaf, Lu, Bin, Wu, Caizhi, Ballon, Carlos, Ouyang, Meng, Wu, Xiaoli S, Jin, Ying, Hwangbo, Yon, Huang, Yu-Han, Somerville, Tim DD, Chang, Kenneth, Park, Jung, Chung, Taemoon, Lyons, Scott K, Shi, Junwei, Vogel, Hannes, Schulder, Michael, Vakoc, Christopher R, Mills, Alea A (December 2022) BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network. Nature. ISSN 0028-0836

Belleau, Pascal, Deschênes, Astrid, Chambwe, Nyasha, Tuveson, David A, Krasnitz, Alexander (December 2022) Genetic ancestry inference from cancer-derived molecular data across genomic and transcriptomic platforms. Cancer Research. CAN-22. ISSN 0008-5472

Barriga, Francisco M, Tsanov, Kaloyan M, Ho, Yu-Jui, Sohail, Noor, Zhang, Amy, Baslan, Timour, Wuest, Alexandra N, Del Priore, Isabella, Meškauskaitė, Brigita, Livshits, Geulah, Alonso-Curbelo, Direna, Simon, Janelle, Chaves-Perez, Almudena, Bar-Sagi, Dafna, Iacobuzio-Donahue, Christine A, Notta, Faiyaz, Chaligne, Ronan, Sharma, Roshan, Pe'er, Dana, Lowe, Scott W (November 2022) MACHETE identifies interferon-encompassing chromosome 9p21.3 deletions as mediators of immune evasion and metastasis. Nature Cancer, 3 (11). pp. 1367-1385. ISSN 2662-1347

Mo, Yan, Duan, Shoufu, Zhang, Xu, Hua, Xu, Zhou, Hui, Wei, Hong-Jian, Watanabe, Jun, McQuillan, Nicholas, Su, Zhenyi, Gu, Wei, Wu, Cheng-Chia, Vakoc, Christopher R, Hashizume, Rintaro, Chang, Kenneth, Zhang, Zhiguo (October 2022) Epigenome programing by H3.3K27M mutation creates a dependence of pediatric glioma on SMARCA4. Cancer Discovery. CD-21. ISSN 2159-8274

Kleeman, Sam O, Cordioli, Mattia, Timmers, Paul RHJ, Khan, Atlas, Tober-Lau, Pinkus, Kurth, Florian, Demichev, Vadim, Meyer, Hannah V, Wilson, James F, Ralser, Markus, Kiryluk, Krzysztof, Ganna, Andrea, Baillie, Kenneth, Janowitz, Tobias (October 2022) Cystatin C is associated with adverse COVID-19 outcomes in diverse populations. iScience, 25 (10). p. 105040. ISSN 2589-0042 (In Press)

Wang, Zihua, Moffitt, Andrea B, Andrews, Peter, Wigler, Michael, Levy, Dan (September 2022) Accurate measurement of microsatellite length by disrupting its tandem repeat structure. Nucleic Acids Research. gkac723. ISSN 0305-1048

Doepner, Miriam, Lee, Inyoung, Natale, Christopher A, Brathwaite, Roderick, Venkat, Swati, Kim, Sung Hoon, Wei, Yiliang, Vakoc, Christopher R, Capell, Brian C, Katzenellenbogen, John A, Katzenellenbogen, Benita S, Feigin, Michael E, Ridky, Todd W (September 2022) Endogenous DOPA inhibits melanoma through suppression of CHRM1 signaling. Science Advances, 8 (35). eabn4007. ISSN 2375-2548

Baslan, Timour, Morris, John P, Zhao, Zhen, Reyes, Jose, Ho, Yu-Jui, Tsanov, Kaloyan M, Bermeo, Jonathan, Tian, Sha, Zhang, Sean, Askan, Gokce, Yavas, Aslihan, Lecomte, Nicolas, Erakky, Amanda, Varghese, Anna M, Zhang, Amy, Kendall, Jude, Ghiban, Elena, Chorbadjiev, Lubomir, Wu, Jie, Dimitrova, Nevenka, Chadalavada, Kalyani, Nanjangud, Gouri J, Bandlamudi, Chaitanya, Gong, Yixiao, Donoghue, Mark TA, Socci, Nicholas D, Krasnitz, Alex, Notta, Faiyaz, Leach, Steve D, Iacobuzio-Donahue, Christine A, Lowe, Scott W (August 2022) Ordered and deterministic cancer genome evolution after p53 loss. Nature. ISSN 0028-0836

Carter, Jason A, Strömich, Léonie, Peacey, Matthew, Chapin, Sarah R, Velten, Lars, Steinmetz, Lars M, Brors, Benedikt, Pinto, Sheena, Meyer, Hannah V (August 2022) Transcriptomic diversity in human medullary thymic epithelial cells. Nature Communications, 13 (1). p. 4296. ISSN 2041-1723

Revia, Steffie, Seretny, Agnieszka, Wendler, Lena, Banito, Ana, Eckert, Christoph, Breuer, Kersten, Mayakonda, Anand, Lutsik, Pavlo, Evert, Matthias, Ribback, Silvia, Gallage, Suchira, Chikh Bakri, Ismaiel, Breuhahn, Kai, Schirmacher, Peter, Heinrich, Stefan, Gaida, Matthias M, Heikenwälder, Mathias, Calvisi, Diego F, Plass, Christoph, Lowe, Scott W, Tschaharganeh, Darjus F (August 2022) Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer. Gut, 71 (8). pp. 1613-1628. ISSN 0017-5749

Song, Dongyan, Adrover, Jose M, Felice, Christy, Christensen, Lisa N, He, Xue-Yan, Merrill, Joseph R, Wilkinson, John E, Janowitz, Tobias, Lyons, Scott K, Egeblad, Mikala, Tonks, Nicholas K (July 2022) PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils. JCI Insight, 7 (14). e158199. ISSN 2379-3708

Li, Siran, Park, Sarah, Ye, Catherine, Danyko, Cassidy, Wroten, Matthew, Andrews, Peter, Wigler, Michael, Levy, Dan (July 2022) Targeted de novo phasing and long-range assembly by template mutagenesis. Nucleic Acids Research. ISSN 0305-1048

Orstad, Grace, Fort, Gabriela, Parnell, Timothy J, Jones, Alex, Stubben, Chris, Lohman, Brian, Gillis, Katherine L, Orellana, Walter, Tariq, Rushmeen, Klingbeil, Olaf, Kaestner, Klaus, Vakoc, Christopher R, Spike, Benjamin T, Snyder, Eric L (July 2022) FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma. Developmental Cell. ISSN 1534-5807

Ferrer, Miriam, Janowitz, Tobias (June 2022) Training the host organism to enhance anti-cancer immunity. Cancer Cell. S1535-6108(22)00267. ISSN 1535-6108

Wu, Xiaoli S, He, Xue-Yan, Ipsaro, Jonathan J, Huang, Yu-Han, Preall, Jonathan B, Ng, David, Shue, Yan Ting, Sage, Julien, Egeblad, Mikala, Joshua-Tor, Leemor, Vakoc, Christopher R (May 2022) OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. ISSN 0028-0836

Li, Ruitong, Klingbeil, Olaf, Monducci, Davide, Young, Michael J, Rodriguez, Diego J, Bayyat, Zaid, Dempster, Joshua M, Kesar, Devishi, Yang, Xiaoping, Zamanighomi, Mahdi, Vakoc, Christopher R, Ito, Takahiro, Sellers, William R (May 2022) Comparative optimization of combinatorial CRISPR screens. Nature Communications, 13 (1). p. 2469. ISSN 2041-1723

Gegenhuber, B, Wu, MV, Bronstein, R, Tollkuhn, J (May 2022) Gene regulation by gonadal hormone receptors underlies brain sex differences. Nature. ISSN 0028-0836

Noyes, Michelle D, Harvey, William T, Porubsky, David, Sulovari, Arvis, Li, Ruiyang, Rose, Nicholas R, Audano, Peter A, Munson, Katherine M, Lewis, Alexandra P, Hoekzema, Kendra, Mantere, Tuomo, Graves-Lindsay, Tina A, Sanders, Ashley D, Goodwin, Sara, Kramer, Melissa, Mokrab, Younes, Zody, Michael C, Hoischen, Alexander, Korbel, Jan O, McCombie, W Richard, Eichler, Evan E (March 2022) Familial long-read sequencing increases yield of de novo mutations. American Journal of Human Genetics. ISSN 0002-9297

Gutbrod, MJ, Roche, B, Steinberg, JI, Lakhani, AA, Chang, K, Schorn, AJ, Martienssen, RA (February 2022) Dicer promotes genome stability via the bromodomain transcriptional co-activator BRD4. Nature Communications, 13 (1). p. 1001. ISSN 2041-1723

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Plenker, Dennis, Tuveson, David A, Rishi, Arvind, Wilkinson, John E, McCombie, W Richard, Kostroff, Karen, Spector, David L (February 2022) Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics. Cancer Research. ISSN 0008-5472

Sánchez-Rivera, Francisco J, Diaz, Bianca J, Kastenhuber, Edward R, Schmidt, Henri, Katti, Alyna, Kennedy, Margaret, Tem, Vincent, Ho, Yu-Jui, Leibold, Josef, Paffenholz, Stella V, Barriga, Francisco M, Chu, Kevan, Goswami, Sukanya, Wuest, Alexandra N, Simon, Janelle M, Tsanov, Kaloyan M, Chakravarty, Debyani, Zhang, Hongxin, Leslie, Christina S, Lowe, Scott W, Dow, Lukas E (February 2022) Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants. Nature Biotechnology. ISSN 1087-0156

Brennan, Christina M, Nadella, Sandeep, Zhao, Xiang, Dima, Richard J, Jordan-Martin, Nicole, Demestichas, Breanna R, Kleeman, Sam O, Ferrer, Miriam, von Gablenz, Eva Carlotta, Mourikis, Nicholas, Rubin, Michael E, Adnani, Harsha, Lee, Hassal, Ha, Taehoon, Prum, Soma, Schleicher, Cheryl B, Fox, Sharon S, Ryan, Michael G, Pili, Christina, Goldberg, Gary, Crawford, James M, Goodwin, Sara, Zhang, Xiaoyue, Preall, Jonathan B, Costa, Ana SH, Conigliaro, Joseph, Masci, Joseph R, Yang, Jie, Tuveson, David A, Tracey, Kevin J, Janowitz, Tobias (February 2022) Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial. Gut. ISSN 0017-5749

Petruzzelli, M, Ferrer, M, Schuijs, MJ, Kleeman, SO, Mourikis, N, Hall, Z, Perera, D, Raghunathan, S, Vacca, M, Gaude, E, Lukey, MJ, Jodrell, DI, Frezza, C, Wagner, EF, Venkitaraman, AR, Halim, TYF, Janowitz, T (February 2022) Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia. Cancers, 14 (4). p. 963. ISSN 2072-6694

Bharathy, Narendra, Cleary, Megan M, Kim, Jin-Ah, Nagamori, Kiyo, Crawford, Kenneth A, Wang, Eric, Saha, Debarya, Settelmeyer, Teagan P, Purohit, Reshma, Skopelitis, Damianos, Chang, Kenneth, Doran, Jessica A, Kirschbaum, C Ward, Bharathy, Suriya, Crews, Davis W, Randolph, Matthew E, Karnezis, Anthony N, Hudson-Price, Lisa, Dhawan, Jyotsna, Michalek, Joel E, Ciulli, Alessio, Vakoc, Christopher R, Keller, Charles (January 2022) SMARCA4 biology in alveolar rhabdomyosarcoma. Oncogene. ISSN 0950-9232

Lin, Xun, Gaudino, Stephen J, Jang, Kyung Ku, Bahadur, Tej, Singh, Ankita, Banerjee, Anirban, Beaupre, Michael, Chu, Timothy, Wong, Hoi Tong, Kim, Chang-Kyung, Kempen, Cody, Axelrad, Jordan, Huang, Huakang, Khalid, Saba, Shah, Vyom, Eskiocak, Onur, Parks, Olivia B, Berisha, Artan, McAleer, Jeremy P, Good, Misty, Hoshino, Miko, Blumberg, Richard, Bialkowska, Agnieszka B, Gaffen, Sarah L, Kolls, Jay K, Yang, Vincent W, Beyaz, Semir, Cadwell, Ken, Kumar, Pawan (January 2022) IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. ISSN 1074-7613

Polyanskaya, Sofya A, Moreno, Rosamaria Y, Lu, Bin, Feng, Ruopeng, Yao, Yu, Irani, Seema, Klingbeil, Olaf, Yang, Zhaolin, Wei, Yiliang, Demerdash, Osama E, Benjamin, Lukas A, Weiss, Mitchell J, Zhang, Yan Jessie, Vakoc, Christopher R (January 2022) SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia. Cell Reports, 38 (2). p. 110233. ISSN 2211-1247

Laubscher, Dominik, Gryder, Berkley E, Sunkel, Benjamin D, Andresson, Thorkell, Wachtel, Marco, Das, Sudipto, Roschitzki, Bernd, Wolski, Witold, Wu, Xiaoli S, Chou, Hsien-Chao, Song, Young K, Wang, Chaoyu, Wei, Jun S, Wang, Meng, Wen, Xinyu, Ngo, Quy Ai, Marques, Joana G, Vakoc, Christopher R, Schäfer, Beat W, Stanton, Benjamin Z, Khan, Javed (November 2021) BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma. Nature Communications, 12 (1). p. 6924. ISSN 2041-1723

Hutton, Elizabeth R, Vakoc, Christopher R, Siepel, Adam (September 2021) ACE: a probabilistic model for characterizing gene-level essentiality in CRISPR screens. Genome Biology, 22 (1). p. 278. ISSN 1474-760X

Baslan, Timour, Kovaka, Sam, Sedlazeck, Fritz J, Zhang, Yanming, Wappel, Robert, Tian, Sha, Lowe, Scott W, Goodwin, Sara, Schatz, Michael C (September 2021) High resolution copy number inference in cancer using short-molecule nanopore sequencing. Nucleic Acids Research. ISSN 0305-1048

Wei, Yiliang, Huang, Yu-Han, Skopelitis, Damianos S, Iyer, Shruti V, Costa, Ana SH, Yang, Zhaolin, Kramer, Melissa, Adelman, Emmalee R, Klingbeil, Olaf, Demerdash, Osama E, Polyanskaya, Sofya A, Chang, Kenneth, Goodwin, Sara, Hodges, Emily, McCombie, W Richard, Figueroa, Maria E, Vakoc, Christopher R (September 2021) SLC5A3-dependent myo-inositol auxotrophy in acute myeloid leukemia. Cancer Discovery. candisc.1849.2020-candisc.1849.2020. ISSN 2159-8274

Lukow, Devon A, Sausville, Erin L, Suri, Pavit, Chunduri, Narendra Kumar, Wieland, Angela, Leu, Justin, Smith, Joan C, Girish, Vishruth, Kumar, Ankith A, Kendall, Jude, Wang, Zihua, Storchova, Zuzana, Sheltzer, Jason M (August 2021) Chromosomal instability accelerates the evolution of resistance to anti-cancer therapies. Developmental Cell. ISSN 1534-5807

Safaric Tepes, Polona, Pal, Debjani, Lindsted, Trine, Ibarra, Ingrid, Lujambio, Amaia, Jimenez Sabinina, Vilma, Senturk, Serif, Miller, Madison, Korimerla, Navya, Huang, Jiahao, Glassman, Lawrence, Lee, Paul, Zeltsman, David, Hyman, Kevin, Esposito, Michael, Hannon, Greg, Sordella, Raffaella (July 2021) An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating miR-335 expression. eLife, 10. ISSN 2050-084X

Kolamunnage-Dona, Ruwanthi, Berhane, Sarah, Potts, Harry, Williams, Edward H, Tanner, James, Janowitz, Tobias, Hoare, Matthew, Johnson, Philip (May 2021) Sorafenib is associated with a reduced rate of tumour growth and liver function deterioration in HCV-induced hepatocellular carcinoma. Journal of Hepatology. ISSN 0168-8278

Fiskus, Warren, Mill, Christopher P, Nabet, Behnam, Perera, Dimuthu, Birdwell, Christine, Manshouri, Taghi, Lara, Bernardo, Kadia, Tapan M, DiNardo, Courtney, Takahashi, Koichi, Daver, Naval, Bose, Prithviraj, Masarova, Lucia, Pemmaraju, Naveen, Kornblau, Steven, Borthakur, Gautam, Montalban-Bravo, Guillermo, Manero, Guillermo Garcia, Sharma, Sunil, Stubbs, Matthew, Su, Xiaoping, Green, Michael R, Coarfa, Cristian, Verstovsek, Srdan, Khoury, Joseph D, Vakoc, Christopher R, Bhalla, Kapil N (May 2021) Superior efficacy of co-targeting GFI1/KDM1A and BRD4 against AML and post-MPN secondary AML cells. Blood Cancer Journal, 11 (5). p. 98. ISSN 2044-5385

Henry, Samantha, Trousdell, Marygrace C, Cyrill, Samantha L, Zhao, Yixin, Feigman, Mary J, Bouhuis, Julia M, Aylard, Dominik A, Siepel, Adam, Dos Santos, Camila O (May 2021) Characterization of Gene Expression Signatures for the Identification of Cellular Heterogeneity in the Developing Mammary Gland. Journal of Mammary Gland Biology and Neoplasia. ISSN 1083-3021

Koo, Peter K, Majdandzic, Antonio, Ploenzke, Matthew, Anand, Praveen, Paul, Steffan B (May 2021) Global importance analysis: An interpretability method to quantify importance of genomic features in deep neural networks. PLoS Computational Biology, 17 (5). e1008925. ISSN 1553-7358

Yang, Zhaolin, Wu, Xiaoli S, Wei, Yiliang, Polyanskaya, Sofya A, Iyer, Shruti V, Jung, Moonjung, Lach, Francis P, Adelman, Emmalee R, Klingbeil, Olaf, Milazzo, Joseph P, Kramer, Melissa, Demerdash, Osama E, Chang, Kenneth, Goodwin, Sara, Hodges, Emily, McCombie, W Richard, Figueroa, Maria E, Smogorzewska, Agata, Vakoc, Christopher R (April 2021) Transcriptional silencing of ALDH2 confers a dependency on Fanconi anemia proteins in acute myeloid leukemia. Cancer Discovery. ISSN 2159-8274

Malik, Sarah A, Zhu, Chencan, Li, Jinyu, LaComb, Joseph F, Denoya, Paula I, Kravets, Igor, Miller, Joshua D, Yang, Jie, Kramer, Melissa, McCombie, W Richard, Robertson, Charles E, Frank, Daniel N, Li, Ellen (April 2021) Impact of preoperative antibiotics and other variables on integrated microbiome-host transcriptomic data generated from colorectal cancer resections. World Journal of Gastroenterology, 27 (14). pp. 1465-1482. ISSN 1007-9327

Janowitz, Tobias, Kleeman, Sam, Vonderheide, Robert H (April 2021) Reconsidering Dexamethasone for Antiemesis when Combining Chemotherapy and Immunotherapy. The Oncologist, 26 (4). pp. 269-273. ISSN 1083-7159

Fearon, Douglas T, Janowitz, Tobias (March 2021) AMD3100/Plerixafor overcomes immune inhibition by the CXCL12-KRT19 coating on pancreatic and colorectal cancer cells. British Journal of Cancer. ISSN 0007-0920

Dachet, Fabien, Brown, James B, Valyi-Nagy, Tibor, Narayan, Kunwar D, Serafini, Anna, Boley, Nathan, Gingeras, Thomas R, Celniker, Susan E, Mohapatra, Gayatry, Loeb, Jeffrey A (March 2021) Selective time-dependent changes in activity and cell-specific gene expression in human postmortem brain. Scientific Reports, 11 (1). p. 6078. ISSN 2045-2322

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Carbini, M., Suarez-Farinas, M., Maki, R. G. (May 2018) A method to summarize toxicity in cancer randomized clinical trials. Clin Cancer Res, 24 (20). pp. 4968-4975. ISSN 1078-0432 (Print)1078-0432

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Danko, C. G., Choate, L. A., Marks, B. A., Rice, E. J., Wang, Z., Chu, T., Martins, A. L., Dukler, N., Coonrod, S. A., Tait Wojno, E. D., Lis, J. T., Kraus, W. L., Siepel, A. (January 2018) Dynamic evolution of regulatory element ensembles in primate CD4(+) T cells. Nat Ecol Evol. pp. 1-12. ISSN 2397-334x

Kumar, V., Rosenbaum, J., Wang, Z., Forcier, T., Ronemus, M., Wigler, M., Levy, D. (January 2018) Partial bisulfite conversion for unique template sequencing. Nucleic Acids Res, 46 (2). e10. ISSN 0305-1048

Alexander, J., Kendall, J., McIndoo, J., Rodgers, L., Aboukhalil, R., Levy, D., Stepansky, A., Sun, G., Chobadjiev, L., Riggs, M., Cox, H., Hakker, I., Nowak, D. G., Laze, J., Llukani, E., Srivastava, A., Gruschow, S., Yadav, S. S., Robinson, B. D., Atwal, G., Trotman, L. C., Lepor, H., Hicks, J. B., Wigler, M., Krasnitz, A. (January 2018) Utility of single cell genomics in diagnostic evaluation of prostate cancer. Cancer Res, 78 (2). pp. 348-358. ISSN 0008-5472

Khan, J. A., Maki, R. G., Ravi, V. (January 2018) Pathologic Angiogenesis of Malignant Vascular Sarcomas: Implications for Treatment. J Clin Oncol, 36 (2). pp. 194-201. ISSN 0732-183x

Xu, Y., Milazzo, J. P., Somerville, T. D. D., Tarumoto, Y., Huang, Y. H., Ostrander, E. L., Wilkinson, J. E., Challen, G. A., Vakoc, C. R. (January 2018) A TFIID-SAGA Perturbation that Targets MYB and Suppresses Acute Myeloid Leukemia. Cancer Cell, 33 (1). 13-28 e8. ISSN 1878-3686 (Electronic)1535-6108 (Linking)

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Vakoc, C. R., Tuveson, D. A. (October 2017) Soils and Seeds That Initiate Pancreatic Cancer Metastasis. Cancer Discov, 7 (10). pp. 1067-1068. ISSN 2159-8274

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Xu, Y., Vakoc, C. R. (July 2017) Targeting Cancer Cells with BET Bromodomain Inhibitors. Cold Spring Harb Perspect Med, 7 (7). ISSN 2157-1422

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Lee, Je H. (July 2017) De Novo Gene Expression Reconstruction in Space. Trends in Molecular Medicine, 23 (7). pp. 583-593. ISSN 1471-4914

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Feigin, M. E., Garvin, T., Bailey, P., Waddell, N., Chang, D. K., Kelley, D. R., Shuai, S., Gallinger, S., McPherson, J. D., Grimmond, S. M., Khurana, E., Stein, L. D., Biankin, A. V., Schatz, M. C., Tuveson, D. A. (June 2017) Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma. Nat Genet, 49 (6). pp. 825-833. ISSN 1061-4036

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Li, J., Sordella, R., Powers, S. (June 2016) Effectors and potential targets selectively upregulated in human KRAS-mutant lung adenocarcinomas. Sci Rep, 6. p. 27891. ISSN 2045-2322 (Electronic)2045-2322 (Linking)

Zhang, Qiang, Zeng, Lei, Shen, Chen, Ju, Ying, Konuma, Tsuyoshi, Zhao, Chengcheng, Vakoc, Christopher R, Zhou, Ming-Ming (June 2016) Structural Mechanism of Transcriptional Regulator NSD3 Recognition by the ET Domain of BRD4. Structure. ISSN 0969-2126

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Bhagwat, A. S., Roe, J. S., Mok, B. Y., Hohmann, A. F., Shi, J., Vakoc, C. R. (April 2016) BET Bromodomain Inhibition Releases the Mediator Complex from Select cis-Regulatory Elements. Cell Rep, 15 (3). pp. 519-30. ISSN 2211-1247 (Electronic)

Schoffski, P., Chawla, S., Maki, R. G., Italiano, A., Gelderblom, H., Choy, E., Grignani, G., Camargo, V., Bauer, S., Rha, S. Y., Blay, J. Y., Hohenberger, P., D'Adamo, D., Guo, M., Chmielowski, B., Le Cesne, A., Demetri, G. D., Patel, S. R. (April 2016) Eribulin versus dacarbazine in previously treated patients with advanced liposarcoma or leiomyosarcoma: a randomised, open-label, multicentre, phase 3 trial. Lancet, 387 (10028). pp. 1629-37. ISSN 0140-6736

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Wang, X., Chen, M., Yu, X., Pornputtapong, N., Chen, H., Zhang, N., Powers, S., Krauthammer, M. (March 2016) Global copy number profiling of cancer genomes. Bioinformatics, 32 (6). pp. 926-928. ISSN 1367-4803

Atwal, G. S., Kinney, J. B. (March 2016) Learning Quantitative Sequence–Function Relationships from Massively Parallel Experiments. Journal of Statistical Physics, 162 (5). pp. 1203-1243. ISSN 00224715

Roberts, N. J., Norris, A. L., Petersen, G. M., Bondy, M. L., Brand, R., Gallinger, S., Kurtz, R. C., Olson, S. H., Rustgi, A. K., Schwartz, A. G., Stoffel, E. M., Syngal, S., Zogopoulos, G., Ali, S. Z., Axilbund, J., Chaffee, K. G., Chen, Y. C., Cote, M. L., Childs, E. J., Douville, C., Goes, F. S., Herman, J. M., Iacobuzio-Donahue, C., Kramer, M., Makohon-Moore, A., McCombie, R. W., McMahon, K. W., Niknafs, N., Parla, J., Pirooznia, M., Potash, J. B., Rhim, A. D., Smith, A. L., Wang, Y., Wolfgang, C. L., Wood, L. D., Zandi, P. P., Goggins, M., Karchin, R., Eshleman, J. R., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Hruban, R. H., Klein, A. P. (February 2016) Whole genome sequencing defines the genetic heterogeneity of familial pancreatic cancer. Cancer Discov, 6 (2). pp. 166-175. ISSN 2159-8290 (Electronic)2159-8274 (Linking)

Wu, S., Powers, S., Zhu, W., Hannun, Y. A. (January 2016) Substantial contribution of extrinsic risk factors to cancer development. Nature, 529 (7584). pp. 43-7. ISSN 0028-0836

Hammell, Christopher M, Hannon, Gregory J (January 2016) Inducing RNAi in Caenorhabditis elegans by Injection of dsRNA. Cold Spring Harbor protocols, 2016 (1). pdb.prot086306. ISSN 1940-3402

Breschi, A., Djebali, S., Gillis, J., Pervouchine, D. D., Dobin, A., Davis, C. A., Gingeras, T. R., Guigo, R. (2016) Gene-specific patterns of expression variation across organs and species. Genome Biol, 17 (1). p. 151. ISSN 1474-760X (Electronic)1474-7596 (Linking)

Shen, Chen, Ipsaro, Jonathan J, Shi, Junwei, Milazzo, Joseph P, Wang, Eric, Roe, Jae-Seok, Suzuki, Yutaka, Pappin, Darryl J, Joshua-Tor, Leemor, Vakoc, Christopher R (December 2015) NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler. Molecular Cell, 60 (6). pp. 847-859. ISSN 1097-2765

Sanchez, Carlos G, Teixeira, Felipe Karam, Czech, Benjamin, Preall, Jonathan B, Zamparini, Andrea L, Seifert, Jessica R K., Malone, Colin D, Hannon, Gregory J, Lehmann, Ruth (December 2015) Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation. Cell Stem Cell, 18 (2). pp. 276-290. ISSN 1934-5909

Bott, A. J., Peng, I. C., Fan, Y., Faubert, B., Zhao, L., Li, J., Neidler, S., Sun, Y., Jaber, N., Krokowski, D., Lu, W., Pan, J. A., Powers, S., Rabinowitz, J., Hatzoglou, M., Murphy, D. J., Jones, R., Wu, S., Girnun, G., Zong, W. X. (December 2015) Oncogenic Myc Induces Expression of Glutamine Synthetase through Promoter Demethylation. Cell Metab, 22 (6). pp. 1068-77. ISSN 1550-4131

Matthews, G. M., Mehdipour, P., Cluse, L. A., Falkenberg, K. J., Wang, E., Roth, M., Santoro, F., Vidacs, E., Stanley, K., House, C. M., Rusche, J. R., Vakoc, C. R., Zuber, J., Minucci, S., Johnstone, R. W. (November 2015) Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies. Blood, 126 (21). pp. 2392-2403. ISSN 1528-0020 (Electronic)0006-4971 (Linking)

Montal, E. D., Dewi, R., Bhalla, K., Ou, L., Hwang, B. J., Ropell, A. E., Gordon, C., Liu, W. J., DeBerardinis, R. J., Sudderth, J., Twaddel, W., Boros, L. G., Shroyer, K. R., Duraisamy, S., Drapkin, R., Powers, R. S., Rohde, J. M., Boxer, M. B., Wong, K. K., Girnun, G. D. (November 2015) PEPCK Coordinates the Regulation of Central Carbon Metabolism to Promote Cancer Cell Growth. Mol Cell, 60 (4). pp. 571-83. ISSN 1097-2765

Chakrabortty, S. K., Prakash, A., Nechooshtan, G., Hearn, S., Gingeras, T. R. (November 2015) Extracellular vesicle-mediated transfer of processed and functional RNY5 RNA. RNA, 21 (11). pp. 1966-1979. ISSN 1469-9001 (Electronic)1355-8382 (Linking)

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Jin, Y., Tam, O. H., Paniagua, E., Hammell, M. (November 2015) TEtranscripts: A package for including transposable elements in differential expression analysis of RNA-seq datasets. Bioinformatics, 31 (22). pp. 3593-3599. ISSN 1367-4811 (Electronic)1367-4803 (Linking)

Yu, Y., Gu, J., Jin, Y., Luo, Y., Preall, J. B., Ma, J., Czech, B., Hannon, G. J. (October 2015) Panoramix enforces piRNA-dependent cotranscriptional silencing. Science, 350 (6258). pp. 339-42. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

Tajima, K., Yae, T., Javaid, S., Tam, O., Comaills, V., Morris, R., Wittner, B. S., Liu, M., Engstrom, A., Takahashi, F., Black, J. C., Ramaswamy, S., Shioda, T., Hammell, M., Haber, D. A., Whetstine, J. R., Maheswaran, S. (September 2015) SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes. Nat Commun, 6. p. 8257. ISSN 2041-1723 (Electronic)2041-1723 (Linking)

Rathert, P., Roth, M., Neumann, T., Muerdter, F., Roe, J. S., Muhar, M., Deswal, S., Cerny-Reiterer, S., Peter, B., Jude, J., Hoffmann, T., Boryn, L. M., Axelsson, E., Schweifer, N., Tontsch-Grunt, U., Dow, L. E., Gianni, D., Pearson, M., Valent, P., Stark, A., Kraut, N., Vakoc, C. R., Zuber, J. (September 2015) Transcriptional plasticity promotes primary and acquired resistance to BET inhibition. Nature, 525. pp. 543-547. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Dobin, A., Gingeras, T. R. (September 2015) Mapping RNA-seq Reads with STAR. Curr Protoc Bioinformatics, 51. 11.14.1-11.14.19. ISSN 1934-340X (Electronic)1934-3396 (Linking)

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Goh, W. S., Falciatori, I., Tam, O. H., Burgess, R., Meikar, O., Kotaja, N., Hammell, M., Hannon, G. J. (May 2015) piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis. Genes Dev, 29 (10). pp. 1032-44. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

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Book

Krasnitz, Alexander (2018) Cancer Bioinformatics. Humana Press. ISBN 9781493988686

This list was generated on Mon Mar 18 05:14:43 2024 EDT.
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