Items where Subject is "enzymes"
- CSHL Subject List (993)
- bioinformatics (993)
- genomics and proteomics (993)
- genetics & nucleic acid processing (993)
- protein structure, function, modification (993)
- protein types (993)
- dicer (21)
- enzymes (993)
- 1P36 (1)
- Akt (11)
- DNA polymerase (30)
- DNAse (3)
- Protease (20)
- RNA polymerase (84)
- dicer (21)
- helicase (37)
- histone deacetylase (16)
- kinase (365)
- luciferase (3)
- phospholipase A (6)
- phospholipase C (2)
- protein phosphatase (63)
- ribonuclease (12)
- synthetases (2)
- telomerase (41)
- topoisomerase (2)
- trypsin (9)
- ubiquitin ligase (29)
- protein types (993)
- protein structure, function, modification (993)
- genetics & nucleic acid processing (993)
- genomics and proteomics (993)
- bioinformatics (993)
A
Abbatemarco, Simona, Bondaz, Alexandra, Schwager, Francoise, Wang, Jing, Hammell, Christopher M, Gotta, Monica (October 2021) PQN-59 and GTBP-1 contribute to stress granule formation but are not essential for their assembly in C. elegans embryos. Journal of Cell Science. ISSN 0021-9533
Abuhashem, Abderhman, Chivu, Alexandra, Zhao, Yixin, Rice, Edward, Siepel, Adam, Danko, Charles, Hadjantonakis, Anna-Katerina (2022) RNA Pol II pausing facilitates phased pluripotency transitions by buffering transcription. bioRxiv. (Submitted)
Ajiro, Masahiko, Awaya, Tomonari, Kim, Young Jin, Iida, Kei, Denawa, Masatsugu, Tanaka, Nobuo, Kurosawa, Ryo, Matsushima, Shingo, Shibata, Saiko, Sakamoto, Tetsunori, Studer, Rolenz, Krainer, Adrian R, Hagiwara, Masatoshi (July 2021) Therapeutic manipulation of IKBKAP mis-splicing with a small molecule to cure familial dysautonomia. Nature Communications, 12 (1). p. 4507. ISSN 2041-1723
Andersen, J. N., Jansen, P. G., Echwald, S. M., Mortensen, O. H., Fukada, T., Del Vecchio, R., Tonks, N. K., Moller, N. P. (January 2004) A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage. FASEB J, 18 (1). pp. 8-30. ISSN 1530-6860 (Electronic)
Andersen, J. N., Tonks, N. K. (2004) Protein tyrosine phosphatase-based therapeutics- lessons from PTP1B. In: Protein phosphatases. Topics in current genetics, 5 . Springer-Verlag, Berlin, pp. 201-230. ISBN 3540205608
Arrazola, M. S., Saquel, C., Catalan, R. J., Barrientos, S. A., Hernandez, D. E., Catenaccio, A., Court, F. A. (May 2019) Axonal degeneration is mediated by necroptosis activation Necroptosis mediates axonal degeneration. J Neurosci, 39 (20). pp. 3832-2844. ISSN 0270-6474
Arrigo, A. P., Tanaka, K., Goldberg, A. L., Welch, W. J. (January 1988) Identity of the 19S 'prosome' particle with the large multifunctional protease complex of mammalian cells (the proteasome). Nature, 331 (6152). pp. 192-4. ISSN 0028-0836
Autexier, C., Pruzan, R., Funk, W. D., Greider, C. W. (November 1996) Reconstitution of human telomerase activity and identification of a minimal functional region of the human telomerase RNA. Embo J, 15 (21). pp. 5928-35. ISSN 0261-4189 (Print)
B
Babb, R., Huang, C. C., Aufiero, D. J., Herr, W. (July 2001) DNA recognition by the herpes simplex virus transactivator VP16: a novel DNA-Binding structure. Molecular and Cellular Biology, 21 (14). pp. 4700-4712. ISSN 0270-7306
Bagrodia, S., Taylor, S. J., Jordon, K. A., Van Aelst, L., Cerione, R. A. (September 1998) A novel regulator of p21-activated kinases. Journal of Biological Chemistry, 273 (37). pp. 23633-23636. ISSN 0021-9258
Balbín, M., Hannon, G. J., Pendás, A. M., Ferrando, A. A., Vizoso, F., Fueyo, A., López-Otín, C. (1996) Functional analysis of a p21(WAF1,CIP1,SDI1) mutant (Arg 94 → Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases. Journal of Biological Chemistry, 271 (26). pp. 15782-15786. ISSN 00219258 (ISSN)
Barford, D. (December 1991) Molecular mechanisms for the control of enzymic activity by protein phosphorylation. Biochim Biophys Acta, 1133 (1). pp. 55-62. ISSN 0006-3002 (Print)0006-3002 (Linking)
Barford, D., Jia, Z. C., Tonks, N. K. (December 1995) Protein tyrosine phosphatases take off. Nature Structural Biology, 2 (12). pp. 1043-1053. ISSN 1072-8368
Barford, D., Keller, J. C., Flint, A. J., Tonks, N. K. (June 1994) Purification and crystallization of the catalytic domain of human protein tyrosine phosphatase 1B expressed in Escherichia coli. Journal of Molecular Biology, 239 (5). pp. 726-730. ISSN 0022-2836
Barnes, Allison C, Rodríguez-Zapata, Fausto, Juárez-Núñez, Karla A, Gates, Daniel J, Janzen, Garrett M, Kur, Andi, Wang, Li, Jensen, Sarah E, Estévez-Palmas, Juan M, Crow, Taylor M, Kavi, Heli S, Pil, Hannah D, Stokes, Ruthie L, Knizner, Kevan T, Aguilar-Rangel, Maria R, Demesa-Arévalo, Edgar, Skopelitis, Tara, Pérez-Limón, Sergio, Stutts, Whitney L, Thompson, Peter, Chiu, Yu-Chun, Jackson, David, Muddiman, David C, Fiehn, Oliver, Runcie, Daniel, Buckler, Edward S, Ross-Ibarra, Jeffrey, Hufford, Matthew B, Sawers, Ruairidh JH, Rellán-Álvarez, Rubén (July 2022) An adaptive teosinte mexicana introgression modulates phosphatidylcholine levels and is associated with maize flowering time. Proceedings of the National Academy of Sciences of USA, 119 (27). e2100036119. ISSN 0027-8424
Barringer, K. J., Orgel, L., Wahl, G., Gingeras, T. R. (1990) Blunt-end and single-strand ligations by Escherichia coli ligase: influence on an in vitro amplication scheme. Gene, 89 (1). pp. 117-122. ISSN 0378-1119
Baumann, U., Targosz, B. S., Lemeer, S., Nikolova, V., Kratzat, S., Fernandez-Saiz, V., Reiter, C., Rudelius, M., Miething, C., Kuster, B., Peschel, C., Keller, U., Bassermann, F. (September 2011) SCF(Fbxo25) suppresses B cell lymphomagenesis by targeting Hax-1 for ubiquitin mediated proteasomal degradation. Onkologie, 34. p. 190. ISSN 0378-584X
Bayer, M., Nawy, T., Giglione, C., Galli, M., Meinnel, T., Lukowitz, W. (March 2009) Paternal Control of Embryonic Patterning in Arabidopsis thaliana. Science, 323 (5920). pp. 1485-1488. ISSN 0036-8075
Bennett, A. M., Tonks, N. K. (November 1997) Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases. Science, 278 (5341). pp. 1288-1291. ISSN 0036-8075
Benoit, M. (August 2020) The Great Escape: How a Plant DNA Virus Hijacks an Imprinted Host Gene to Avoid Silencing. Plant Cell, 32 (10). pp. 3051-3052. ISSN 1040-4651
Bergmann, J. H., Jakubsche, J. N., Martins, N. M., Kagansky, A., Nakano, M., Kimura, H., Kelly, D. A., Turner, B. M., Masumoto, H., Larionov, V., Earnshaw, W. C. (January 2012) Epigenetic engineering: Histone H3K9 acetylation is compatible with kinetochore structure and function. Journal of Cell Science, 125 (2). pp. 411-421. ISSN 00219533 (ISSN)
Bernstein, E., Kim, S. Y., Carmell, M. A., Murchison, E. P., Alcorn, H., Li, M. Z., Mills, A. A., Elledge, S. J., Anderson, K. V., Hannon, G. J. (2003) Dicer is essential for mouse development. Nature Genetics, 35 (3). pp. 215-217. ISSN 10614036 (ISSN)
Bharathy, N., Berlow, N. E., Wang, E., Abraham, J., Settelmeyer, T. P., Hooper, J. E., Svalina, M. N., Bajwa, Z., Goros, M. W., Hernandez, B. S., Wolff, J. E., Pal, R., Davies, A. M., Ashok, A., Bushby, D., Mancini, M., Noakes, C., Goodwin, N. C., Ordentlich, P., Keck, J., Hawkins, D. S., Rudzinski, E. R., Mansoor, A., Perkins, T. J., Vakoc, C. R., Michalek, J. E., Keller, C. (May 2019) Preclinical rationale for entinostat in embryonal rhabdomyosarcoma. Skelet Muscle, 9 (1). p. 12. ISSN 2044-5040
Bharathy, Narendra, Cleary, Megan M, Kim, Jin-Ah, Nagamori, Kiyo, Crawford, Kenneth A, Wang, Eric, Saha, Debarya, Settelmeyer, Teagan P, Purohit, Reshma, Skopelitis, Damianos, Chang, Kenneth, Doran, Jessica A, Kirschbaum, C Ward, Bharathy, Suriya, Crews, Davis W, Randolph, Matthew E, Karnezis, Anthony N, Hudson-Price, Lisa, Dhawan, Jyotsna, Michalek, Joel E, Ciulli, Alessio, Vakoc, Christopher R, Keller, Charles (January 2022) SMARCA4 biology in alveolar rhabdomyosarcoma. Oncogene. ISSN 0950-9232
Bianchi, C., Sellke, F. W., Del Vecchio, R. L., Tonks, N. K., Neel, B. G. (April 1999) Receptor-type protein-tyrosine phosphatase mu is expressed in specific vascular endothelial beds in vivo. Experimental Cell Research, 248 (1). pp. 329-338. ISSN 0014-4827
Bish, R. A., Fregoso, O. I., Piccini, A., Myers, M. P. (August 2008) Conjugation of Complex Polyubiquitin Chains to WRNIP1. J Proteome Res, 7 (8). 3481-3489 .
Bivona, T. G., Hieronymus, H., Parker, J., Chang, K., Taron, M., Rosell, R., Moonsamy, P., Dahlman, K., Miller, V. A., Costa, C., Hannon, G. J., Sawyers, C. L. (March 2011) FAS and NF-kappa B signalling modulate dependence of lung cancers on mutant EGFR. Nature, 471 (7339). pp. 523-526. ISSN 0028-0836
Boato, Francesco, Guan, Xiaofei, Zhu, Yanjie, Ryu, Youngjae, Voutounou, Mariel, Rynne, Christopher, Freschlin, Chase R, Zumbo, Paul, Betel, Doron, Matho, Katie, Makarov, Sergey N, Wu, Zhuhao, Son, Young-Jin, Nummenmaa, Aapo, Huang, Josh Z, Edwards, Dylan J, Zhong, Jian (January 2023) Activation of MAP2K signaling by genetic engineering or HF-rTMS promotes corticospinal axon sprouting and functional regeneration. Science Translational Medicine, 15 (677). eabq6885. ISSN 1946-6234 (Public Dataset)
Bodineau, Clément, Tomé, Mercedes, Courtois, Sarah, Costa, Ana SH, Sciacovelli, Marco, Rousseau, Benoit, Richard, Elodie, Vacher, Pierre, Parejo-Pérez, Carlos, Bessede, Emilie, Varon, Christine, Soubeyran, Pierre, Frezza, Christian, Murdoch, Piedad Del Socorro, Villar, Victor H, Durán, Raúl V (August 2021) Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis. Nature Communications, 12 (1). p. 4814. ISSN 2041-1723
Boivin, B., Chaudhary, F., Dickinson, B. C., Haque, A., Pero, S. C., Chang, C. J., Tonks, N. K. (November 2013) Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein mediated mammary epithelial cell motility. Journal of Biological Chemistry, 288 (52). pp. 36926-36935. ISSN 00219258 (ISSN)
Boivin, B., Zhang, S. H., Arbiser, J. L., Zhang, Z.-Y., Tonks, N. K. (July 2008) A modified cysteinyl-labeling assay reveals reversible oxidation of classical and dual specificity phosphatases in angiomyolipoma cells. Proc Natl Acad Sci U S A, 105 (29). pp. 9959-9964.
Bonham, ChristopherA, Mandati, Vinay, Singh, RakeshK, Pappin, DarrylJ, Tonks, NicholasK (March 2023) Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks. Journal of Biological Chemistry. p. 104582. ISSN 0021-9258
Borg, M, Jacob, Y., Susaki, D., LeBlanc, C., Buendia, D, Axelsson, E., Kawashima, T., Voigt, P., Boavida, L. C., Becker, J. D., Higashiyama, T., Martienssen, R. A., Berger, F. (June 2020) Targeted reprogramming of H3K27me3 resets epigenetic memory in plant paternal chromatin. Nature Cell Biology, 22 (6). p. 621. ISSN 1465-7392
Borges, F., Donoghue, M. T. A., LeBlanc, C., Wear, E. E., Tanurdžić, M., Berube, B., Brooks, A., Thompson, W. F., Hanley-Bowdoin, L., Martienssen, R. A. (November 2020) Loss of Small-RNA-Directed DNA Methylation in the Plant Cell Cycle Promotes Germline Reprogramming and Somaclonal Variation. Curr Biol, 31 (3). pp. 591-600. ISSN 0960-9822
Bott, A. J., Shen, J., Tonelli, C., Zhan, L., Sivaram, N., Jiang, Y. P., Yu, X., Bhatt, V., Chiles, E., Zhong, H., Maimouni, S., Dai, W., Velasquez, S., Pan, J. A., Muthalagu, N., Morton, J., Anthony, T. G., Feng, H., Lamers, W. H., Murphy, D. J., Guo, J. Y., Jin, J., Crawford, H. C., Zhang, L., White, E., Lin, R. Z., Su, X., Tuveson, D. A., Zong, W. X. (October 2019) Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Rep, 29 (5). 1287-1298.e6.
Brady-Kalnay, S. M., Flint, A. J., Tonks, N. K. (August 1993) Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation. Journal of Cell Biology, 122 (4). pp. 961-972. ISSN 0021-9525
Brady-Kalnay, S. M., Mourton, T., Nixon, J. P., Pietz, G. E., Kinch, M., Chen, H. Y., Brackenbury, R., Rimm, D. L., Del Vecchio, R. L., Tonks, N. K. (April 1998) Dynamic interaction of PTP mu with multiple cadherins in vivo. Journal of Cell Biology, 141 (1). pp. 287-296. ISSN 0021-9525
Brady-Kalnay, S. M., Rimm, D. L., Tonks, N. K. (August 1995) Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo. Journal of Cell Biology, 130 (4). pp. 977-986. ISSN 0021-9525
Brady-Kalnay, S. M., Rimm, D. L., Tonks, N. K. (November 1995) The receptor protein-tyrosine-phosphatase PTP-mu associates with cadherins and catenins. Molecular Biology of the Cell, 6. p. 676. ISSN 1059-1524
Brady-Kalnay, S. M., Tonks, N. K. (November 1994) Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu. Journal of Biological Chemistry, 269 (45). pp. 28472-28477. ISSN 0021-9258
Brady-Kalnay, S. M., Tonks, N. K. (October 1995) Protein tyrosine phosphatases as adhesion receptors. Current Opinion in Cell Biology, 7 (5). pp. 650-657. ISSN 0955-0674
Brady-Kalnay, S. M., Tonks, N. K. (November 1993) Purification and characterization of the human protein tyrosine phosphatase, PTP mu, from a baculovirus expression system. Molecular and Cellular Biochemistry, 128. pp. 131-141. ISSN 0300-8177
Brand, S. R., Kobayashi, R., Mathews, M. B. (March 1997) The Tat protein of human immunodeficiency virus type 1 is a substrate and inhibitor of the interferon-induced, virally activated protein kinase, PKR. Journal of Biological Chemistry, 272 (13). pp. 8388-95. ISSN 0021-9258
Broach, J., Toda, T., Kataoka, T., Powers, S., Broek, D., Wigler, M. H. (1985) Ras Proteins Function Exclusively to Modulate Adenylate-Cyclase Activity in the Yeast Saccharomyces. DNA-a Journal of Molecular & Cellular Biology, 4 (1). p. 64. ISSN 0198-0238
Broach, J. R. (June 1979) Galactose regulation in Saccharomyces cerevisiae. The enzymes encoded by the GAL7, 10, 1 cluster are co-ordinately controlled and separately translated. J Mol Biol, 131 (1). pp. 41-53. ISSN 0022-2836 (Print)0022-2836 (Linking)
Broek, D., Samily, N., Fasano, O., Fujiyama, A., Tamanoi, F., Northup, J., Wigler, M. H. (1985) Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins. Cell, 41 (3). pp. 763-770.
Broek, D., Toda, T., Michaeli, T., Levin, L., Birchmeier, C., Zoller, M., Powers, S., Wigler, M. H. (March 1987) The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway. Cell, 48 (5). pp. 789-800.
Brondello, J. M., McKenzie, F. R., Sun, H., Tonks, N. K., Pouyssegur, J. (May 1995) Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts. Oncogene, 10 (10). pp. 1895-1904. ISSN 0950-9232
Brooks, J. E., Blumenthal, R. M., Gingeras, T. R. (1983) The isolation and characterization of the Esherichia Coli DNA adenine methylase (dam) gene. Nucleic Acids Research, 11 (3). pp. 837-851. ISSN 03051048 (ISSN)
Broughton, S. J., Tully, T., Greenspan, R. J. (January 2003) Conditioning deficits of CaM-kinase transgenic Drosophila melanogaster in a new excitatory courtship assay. Journal of Neurogenetics, 17 (1). pp. 91-102. ISSN 0167-7063
Brägelmann, Johannes, Lorenz, Carina, Borchmann, Sven, Nishii, Kazuya, Wegner, Julia, Meder, Lydia, Ostendorp, Jenny, Ast, David F, Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A, Plenker, Dennis, Klein, Sebastian, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K, Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D'Rozario, Joshua, Thomas, Emily S, Li, Henry, Schmitt, Clemens A, George, Julie, Thomas, Roman K, von Karstedt, Silvia, Hartmann, Gunther, Büttner, Reinhard, Ullrich, Roland T, Siveke, Jens T, Ohashi, Kadoaki, Schlee, Martin, Sos, Martin L (September 2021) MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nature Communications, 12 (1). p. 5505. ISSN 2041-1723
Burgess, D. J., Doles, J., Zender, L., Xue, W., Ma, B., McCombie, W. R., Hannon, G. J., Lowe, S. W., Hemann, M. T. (July 2008) Topoisomerase levels determine chemotherapy response in vitro and in vivo. Proc Natl Acad Sci U S A, 105 (25). pp. 9053-9058.
Bywater, M. J., Poortinga, G., Sanij, E., Hein, N., Peck, A., Cullinane, C., Wall, M., Cluse, L., Drygin, D., Anderes, K., Huser, N., Proffitt, C., Bliesath, J., Haddach, M., Schwaebe, M. K., Ryckman, D. M., Rice, W. G, Schmitt, C., Lowe, Scott W, Johnstone, R. W., Pearson, R. B., McArthur, G. A., Hannan, R. D. (July 2012) Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53. Cancer Cell, 22 (1). pp. 51-65. ISSN 1535-6108
C
Canaran, P., Buckler, E. S., Glaubitz, J. C., Stein, L. D., Sun, Q., Zhao, W., Ware, D. H. (2008) Panzea: an update on new content and features. Nucleic Acids Res, 36 (Databa). D1041-3.
Castellano, S., Macchi, F., Scali, M., Huang, Z. J., Bozzi, Y. (September 2006) Cytosolic branched chain aminotransferase (BCATc) mRNA is up-regulated in restricted brain areas of BDNF transgenic mice. Brain Research, 1108 (1). pp. 12-18. ISSN 00068993
Charbonneau, H., Tonks, N. K. (1992) 1002 Protein Phosphatases? Annual Review of Cell Biology, 8. pp. 463-493. ISSN 0743-4634
Charles, C. H., Sun, H., Lau, L. F., Tonks, N. K. (June 1993) The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 90 (11). pp. 5292-5296. ISSN 0027-8424
Chen, H. H., Luche, R., Wei, B., Tonks, N. K. (October 2004) Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2. J Biol Chem, 279 (40). pp. 41404-13. ISSN 0021-9258 (Print)
Chen, J., Kim, Y. C., Jung, Y. C., Xuan, Z. Y., Dworkin, G., Zhang, Y. M., Zhang, M. Q., Wang, S. M. (2008) Scanning the human genome at kilobase resolution. Genome Res, 18 (5). pp. 751-762. ISSN 1088-9051
Chen, Z. Q., Speck, C., Wendel, P., Tang, C. Y., Stillman, B., Lill, H. L. (July 2008) The architecture of the DNA replication origin recognition complex in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America, 105 (30). pp. 10326-10331. ISSN 0027-8424
Chiang, H-C., Wang, L., Xie, Z. L., Yau, A., Zhong, Y. (April 2010) PI3 kinase signaling is involved in A beta-induced memory loss in Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 107 (15). pp. 7060-7065. ISSN 0027-8424
Ciccone, M. F., Trousdell, M. C., Dos Santos, C. O. (November 2020) Characterization of Organoid Cultures to Study the Effects of Pregnancy Hormones on the Epigenome and Transcriptional Output of Mammary Epithelial Cells. J Mammary Gland Biol Neoplasia, 25 (4). pp. 351-366. ISSN 1083-3021
Clark, J. W., Camidge, D. R., Kwak, E. L., Maki, R. G., Shapiro, G. I., Chen, I., Tan, W., Randolph, S., Christensen, J. G., Ozeck, M., Tang, Y., Wilner, K. D., Salgia, R. (January 2020) Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer. Future Oncol, 16 (1). pp. 4289-4301. ISSN 1479-6694
Coghlan, V. M., Perrino, B. A., Howard, M., Langeberg, L. K., Hicks, J. B., Gallatin, W. M., Scott, J. D. (1995) Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science, 267 (5195). pp. 108-111. ISSN 00368075 (ISSN)
Concepcion, Carla P, Ma, Sai, LaFave, Lindsay M, Bhutkar, Arjun, Liu, Manyuan, DeAngelo, Lydia P, Kim, Jonathan Y, Del Priore, Isabella, Schoenfeld, Adam J, Miller, Manon, Kartha, Vinay K, Westcott, Peter MK, Sánchez-Rivera, Francisco J, Meli, Kevin, Gupta, Manav, Bronson, Roderick T, Riely, Gregory J, Rekhtman, Natasha, Rudin, Charles M, Kim, Carla F, Regev, Aviv, Buenrostro, Jason D, Jacks, Tyler (February 2022) Smarca4 Inactivation Promotes Lineage-Specific Transformation and Early Metastatic Features in the Lung. Cancer Discovery, 12 (2). pp. 562-585. ISSN 0008-5472
Connelly, Carla J, Vidal-Cardenas, Sofia, Goldsmith, Stephanie, Greider, Carol W (November 2021) The Bur1 cyclin-dependent kinase regulates telomere length in Saccharomyces cerevisiae. Yeast. ISSN 0749-503X
Cool, D. E., Andreassen, P. R., Tonks, N. K., Krebs, E. G., Fischer, E. H., Margolis, R. L. (June 1992) Cytokinetic failure and asynchronous nuclear division in BHK cells overexpressing a truncated protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 89 (12). pp. 5422-5426. ISSN 0027-8424
D
Dagnell, M., Frijhoff, J., Pader, I., Augsten, M., Boivin, B., Xu, J., Mandal, P. K., Tonks, N. K., Hellberg, C., Conrad, M., Arnér, E. S. J., Östman, A. (August 2013) Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-ß receptor tyrosine kinase signaling. Proceedings of the National Academy of Sciences of the United States of America, 110 (33). pp. 13398-13403. ISSN 00278424
Davis, L. E., Bolejack, V., Ryan, C. W., Ganjoo, K. N., Loggers, E. T., Chawla, S., Agulnik, M., Livingston, M. B., Reed, D., Keedy, V., Rushing, D., Okuno, S., Reinke, D. K., Riedel, R. F., Attia, S., Mascarenhas, L., Maki, R. G. (June 2019) Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma. J Clin Oncol, 37 (16). pp. 1424-1431. ISSN 0732-183x
Degenhardt, Y., Greshock, J., Laquerre, S., Gilmartin, A. G., Jing, J., Richter, M., Zhang, X., Bleam, M., Halsey, W., Hughes, A., Moy, C., Liu-Sullivan, N., Powers, S., Bachman, K., Jackson, J., Weber, B., Wooster, R. (July 2010) Sensitivity of Cancer Cells to Plk1 Inhibitor GSK461364A Is Associated with Loss of p53 Function and Chromosome Instability. Molecular Cancer Therapeutics, 9 (7). pp. 2079-2089. ISSN 1535-7163
Delas, M. J., Jackson, B. T., Kovacevic, T., Vangelisti, S., Munera Maravilla, E., Wild, S. A., Stork, E. M., Erard, N., Knott, S. R. V., Hannon, G. J. (April 2019) lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation. Cell Rep, 27 (3). 719-729.e6.
Delvecchio, R. L., Tonks, N. K. (July 1994) Characterization of two structurally related Xenopus laevis protein tyrosine phosphatases with homology to lipid-binding proteins. Journal of Biological Chemistry, 269 (30). pp. 19639-19645. ISSN 0021-9258
Demicco, E. G., Wani, K., Ingram, D., Wagner, M., Maki, R. G., Rizzo, A., Meeker, A., Lazar, A. J., Wang, W. L. (November 2018) TERT Promoter Mutations in Solitary Fibrous Tumor. Histopathology, 73 (5). pp. 843-851. ISSN 0309-0167
Dent, P., Booth, L., Roberts, J. L., Liu, J., Poklepovic, A., Lalani, A. S., Tuveson, D., Martinez, J., Hancock, J. F. (June 2019) Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. Oncogene. ISSN 0950-9232
Di Cristofano, A., Niki, M., Zhao, M. M., Karnell, F. G., Clarkson, B., Pear, W. S., Van Aelst, L., Pandolfi, P. P. (August 2001) p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl). Journal of Experimental Medicine, 194 (3). pp. 275-284. ISSN 0022-1007
Dokshin, G. A., Davis, G. M., Sawle, A. D., Eldridge, M. D., Nicholls, P. K., Gourley, T. E., Romer, K. A., Molesworth, L. W., Tatnell, H. R., Ozturk, A. R., de Rooij, D. G., Hannon, G. J., Page, D. C., Mello, C. C., Carmell, M. A. (December 2019) GCNA Interacts with Spartan and Topoisomerase II to Regulate Genome Stability. Dev Cell. ISSN 1534-5807 (Public Dataset)
Dong, O. X., Ao, K., Xu, F., Johnson, K. C. M., Wu, Y., Li, L., Xia, S., Liu, Y., Huang, Y., Rodriguez, E., Chen, X., Chen, S., Zhang, Y., Petersen, M., Li, X. (August 2018) Individual components of paired typical NLR immune receptors are regulated by distinct E3 ligases. Nat Plants, 4 (9). pp. 699-710. ISSN 2055-0278
Du, J., Hannon, G. J. (2002) The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1. Nucleic Acids Research, 30 (24). pp. 5465-5475. ISSN 03051048 (ISSN)
Du, J., Jablonski, S., Yen, T. J., Hannon, G. J. (2008) Astrin regulates Aurora-A localization. Biochem Biophys Res Commun, 370 (2). pp. 213-9.
Dukler, N., Huang, Y-F., Siepel, A. (March 2020) Phylogenetic Modeling of Regulatory Element Turnover Based on Epigenomic Data. Mol Biol Evol, 37 (7). pp. 2137-2152. ISSN 0737-4038
Dutta, A., Din, S., Brill, S. J., Stillman, B. (1991) Phosphorylation of replication protein A: A role for cdc2 kinase in G1/S regulation. Cold Spring Harbor Symposia on Quantitative Biology, 56. pp. 315-324. ISSN 00917451 (ISSN)
de Oliveira, Beatriz Cristina Dias, Shiburah, Mark Ewusi, Assis, Luiz Henrique Castro, Fontes, Veronica Silva, Bisetegn, Habtye, de Oliveira Passos, Arthur, de Oliveira, Leilane S, de Santis Alves, Cristiane, Ernst, Evan, Martienssen, Rob, Gallo-Francisco, Pedro Henrique, Giorgio, Selma, Batista, Marcos Meuser, de Nazaré Correia Soeiro, Maria, Menna-Barreto, Rubem Figueiredo Sadok, Aoki, Juliana Ide, Coelho, Adriano Cappellazzo, Cano, Maria Isabel Nogueira (August 2024) Leishmania major telomerase RNA knockout: From altered cell proliferation to decreased parasite infectivity. International Journal of Biological Macromolecules. p. 135150. ISSN 0141-8130
de Sevilla, D. F., Núñez, A., Borde, M., Malinow, R., Buño, W. (2008) Cholinergic-mediated IP3-ereceptor activation induces long-lasting synaptic enhancement in CA1 pyramidal neurons. Journal of Neuroscience, 28 (6). pp. 1469-1478. ISSN 0270-6474
E
Egeblad, M., Kouros-Mehr, H., Welm, B. E., Ortega, N., Cunha, G. R., Werb, Z. (November 2002) MMP-9 in mouse mammary cancer. Molecular Biology of the Cell, 13. 209A-210A. ISSN 1059-1524
Egeblad, M., Shen, H. C. J., Behonick, D. J., Wilmes, L., Eichten, A., Korets, L. V., Kheradmand, F., Werb, Z., Coussens, L. M. (2007) Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development. Developmental Dynamics, 236 (6). pp. 1683-1693. ISSN 10588388 (ISSN)
Egeblad, M., Werb, Z. (2002) New functions for the matrix metalloproteinases in cancer progression. Nature Reviews Cancer, 2 (3). pp. 161-174. ISSN 1474175X (ISSN)
Ehrenhofer-Wolfer, K., Puchner, T., Schwarz, C., Rippka, J., Blaha-Ostermann, S., Strobl, U., Hormann, A., Bader, G., Kornigg, S., Zahn, S., Sommergruber, W., Schweifer, N., Zichner, T., Schlattl, A., Neumuller, R. A., Shi, J., Vakoc, C. R., Kogl, M., Petronczki, M., Kraut, N., Pearson, M. A., Wohrle, S. (August 2019) SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines. Sci Rep, 9 (1). p. 11661. ISSN 2045-2322
Eifert, C., Wang, X., Kokabee, L., Kourtidis, A., Jain, R., Gerdes, M. J., Conklin, D. S. (October 2013) A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis. Genes Chromosomes and Cancer, 52 (10). pp. 961-975. ISSN 10452257
Ellis, L., Bots, M., Lindemann, R. K., Bolden, J. E., Newbold, A., Cluse, L. A., Scott, C. L., Strasser, A., Atadja, P., Lowe, S. W., Johnstone, R. W. (July 2009) The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy. Blood, 114 (2). pp. 380-393.
Enemark, E. J., Joshua-Tor, L. (April 2008) On helicases and other motor proteins. Curr Opin Struct Biol, 18 (2). 243-257 .
Englesberg, Ellis (1957) The physiological basis for rhamnose utilization by a mutant of Pasteurella pestis. II. A single mutational event leading to the production of two enzymes. Archives of Biochemistry and Biophysiology, 71. p. 179.
Englesberg, Ellis, Levy, Judith Bentoff (1955) The induced synthesis of enzymes in the tricarboxylic acid cycle as correlated with the induced oxidation of acetate and glucose by Pasteurella pestis. Journal of Bacteriology, 69 (4). pp. 418-431.
Enikolopov, G. N. (November 2011) Talk from Grigori Enikolopov at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)
Escarceller, M., Hicks, J., Gudmundsson, G., Trump, G., Touati, D., Lovett, S., Foster, P. L., McEntee, K., Goodman, M. F. (1994) Involvement of Escherichia coli DNA polymerase II in response to oxidative damage and adaptive mutation. Journal of Bacteriology, 176 (20). pp. 6221-6228. ISSN 00219193 (ISSN)
F
Fan, G., Lin, G., Lucito, R., Tonks, N. K. (June 2013) Protein Tyrosine Phosphatase 1B Antagonized Signaling by IGF-1 Receptor and BRK/PTK6 in Ovarian Cancer Cells. Journal of Biological Chemistry, 288 (34). pp. 24923-29434. ISSN 0021-9258
Farrell, Brian M, Gerth, Fabian, Yang, Cheng-Hao R, Yeh, Johannes T-H (September 2022) A synthetic KLHL20 ligand to validate CUL3KLHL20 as a potent E3 ligase for targeted protein degradation. Genes and Development, 36 (17-18). pp. 1031-1042. ISSN 0890-9369
Feramisco, J. R., Glass, D. B., Krebs, E. G. (1980) Optimal Spatial Requirements for the Location of Basic Residues in Peptide Substrates for the Cyclic Amp Dependent Protein Kinase. Journal of Biological Chemistry, 255 (9). pp. 4240-4245.
Field, J., Broek, D., Kataoka, T., Wigler, M. H. (1987) Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae. Molecular & Cellular Biology, 7 (6). pp. 2128-2133.
Fischer, E. H., Charbonneau, H., Cool, D. E., Tonks, N. K. (1992) Tyrosine phosphatases and their possible interplay with tyrosine kinases. Ciba Foundation Symposia, 164. pp. 132-144. ISSN 0300-5208
Fischer, E. H., Charbonneau, H., Tonks, N. K. (July 1991) Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes. Science, 253 (5018). pp. 401-406. ISSN 0036-8075
Fisher, Matthew L, Balinth, Seamus, Hwangbo, Yon, Wu, Caizhi, Ballon, Carlos, Goldberg, Gary L, Mills, Alea A (August 2023) Cancer-associated fibroblasts promote cancer stemness by inducing expression of the chromatin-modifying protein CBX4 in squamous cell carcinoma. Carcinogenesis, 44 (6). pp. 485-496. ISSN 0143-3334
Fitzgerlad, G. F., Daly, C., Brown, L. R., Gingeras, T. R. (1982) ScrFi: A new sequence-specific endonuclease from Streptococcus cremoris. Nucleic Acids Research, 10 (24). pp. 8171-8179. ISSN 03051048 (ISSN)
Flint, A. J., Gebbink, M. F., Franza, B. R., Hill, D. E., Tonks, N. K. (May 1993) Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation. Embo Journal, 12 (5). pp. 1937-1946. ISSN 0261-4189
Flint, A. J., Tiganis, T., Barford, D., Tonks, N. K. (March 1997) Development of ''substrate-trapping'' mutants to identify physiological substrates of protein tyrosine phosphatases. Proceedings of the National Academy of Sciences of the United States of America, 94 (5). pp. 1680-1685. ISSN 0027-8424
Foronda, M., Tarumoto, Y., Schatoff, E. M., Leach, B. I., Diaz, B. J., Zimmerman, J., Goswami, S., Shusterman, M., Vakoc, C. R., Dow, L. E. (December 2019) Tankyrase inhibition sensitizes cells to CDK4 blockade. PLoS One, 14 (12). e0226645. ISSN 1932-6203
Fukada, T., Tonks, N. K. (February 2003) Identification of YB-1 as a regulator of PTP1B expression: implications for regulation of insulin and cytokine signaling. Embo Journal, 22 (3). pp. 479-493. ISSN 0261-4189
Fukada, T., Tonks, N. K. (July 2001) The reciprocal role of Egr-1 and Sp family proteins in regulation of the PTP1B promoter in response to the p210 Bcr-Abl oncoprotein-tyrosine kinase. Journal of Biological Chemistry, 276 (27). pp. 25512-25519. ISSN 0021-9258
Fuller, S. J., Davies, E. L., Gillespie Brown, J., Sun, H., Tonks, N. K. (April 1997) Mitogen-activated protein kinase phosphatase 1 inhibits the stimulation of gene expression by hypertrophic agonists in cardiac myocytes. Biochemical Journal, 323. pp. 313-319. ISSN 0264-6021
Fuortes, M., Melchior, M., Han, H., Lyon, G. J., Nathan, C. (August 1999) Role of the tyrosine kinase pyk2 in the integrin-dependent activation of human neutrophils by TNF. Journal of Clinical Investigation, 104 (3). pp. 327-335. ISSN 0021-9738
G
Galic, S., Klingler-Hoffmann, M., Fodero-Tavoletti, M. T., Puryer, M. A., Meng, T. C., Tonks, N. K., Tiganis, T. (March 2003) Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP. Molecular and Cellular Biology, 23 (6). pp. 2096-2108. ISSN 0270-7306
Garton, A. J., Burnham, M. R., Bouton, A. H., Tonks, N. K. (August 1997) Association of PTP-PEST with the SH3 domain of p130(cas); a novel mechanism of protein tyrosine phosphatase substrate recognition. Oncogene, 15 (8). pp. 877-885. ISSN 0950-9232
Garton, A. J., Flint, A. J., Tonks, N. K. (November 1996) Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST. Molecular and Cellular Biology, 16 (11). pp. 6408-6418. ISSN 0270-7306
Garton, A. J., Tonks, N. K. (August 1994) PTP-PEST: a protein tyrosine phosphatase regulated by serine phosphorylation. Embo Journal, 13 (16). pp. 3763-3771. ISSN 0261-4189
Garton, A. J., Tonks, N. K. (February 1999) Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST. Journal of Biological Chemistry, 274 (6). pp. 3811-3818. ISSN 0021-9258
Gilman, M. (2001) Ribonuclease protection assay. In: Current Protocols in Molecular Biology. Wiley InterScience.
Girbig, Mathias, Xie, Juanjuan, Grötsch, Helga, Libri, Domenico, Porrua, Odil, Müller, Christoph W (September 2022) Architecture of the yeast Pol III pre-termination complex and pausing mechanism on poly(dT) termination signals. Cell Reports, 40 (10). p. 111316. ISSN 2211-1247
Goldberg, M., Stucki, M., Falck, J., D'Amours, D., Rahman, D., Pappin, D., Bartek, J., Jackson, S. P. (February 2003) MDC1 is required for the intra-S-phase DNA damage checkpoint. Nature, 421 (6926). pp. 952-6. ISSN 0028-0836 (Print)0028-0836 (Linking)
Gryder, B. E., Pomella, S., Sayers, C., Wu, X. S., Song, Y., Chiarella, A. M., Bagchi, S., Chou, H. C., Sinniah, R. S., Walton, A., Wen, X., Rota, R., Hathaway, N. A., Zhao, K., Chen, J., Vakoc, C. R., Shern, J. F., Stanton, B. Z., Khan, J. (December 2019) Histone hyperacetylation disrupts core gene regulatory architecture in rhabdomyosarcoma. Nat Genet, 51 (12). pp. 1714-1722. ISSN 1061-4036 (Public Dataset)
Gutbrod, MJ, Roche, B, Steinberg, JI, Lakhani, AA, Chang, K, Schorn, AJ, Martienssen, RA (February 2022) Dicer promotes genome stability via the bromodomain transcriptional co-activator BRD4. Nature Communications, 13 (1). p. 1001. ISSN 2041-1723
Gutch, M. J., Flint, A. J., Keller, J., Tonks, N. K., Hengartner, M. O. (February 1998) The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development. Genes & Development, 12 (4). pp. 571-585. ISSN 0890-9369
Gyrd-Hansen, M., Darding, M., Miasari, M., Santoro, M. M., Zender, L., Xue, W., Tenev, T., da Fonseca, P. C., Zvelebil, M., Bujnicki, J. M., Lowe, S. W., Silke, J., Meier, P. (November 2008) IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis. Nat Cell Biol, 10 (11). pp. 1309-17.
H
Hanley, S. Z., Pappin, D. J., Rahman, D., White, A. J., Elborough, K. M., Slabas, A. R. (March 1999) Re-evaluation of the primary structure of Ralstonia eutropha phasin and implications for polyhydroxyalkanoic acid granule binding. FEBS Letters, 447 (1). pp. 99-105. ISSN 0014-5793 (Print)0014-5793 (Linking)
Hannon, G. J., Casso, D., Beach, D. (1994) KAP: A dual specificity phosphatase that interacts with cyclin-dependent kinases. Proceedings of the National Academy of Sciences of the United States of America, 91 (5). pp. 1731-1735. ISSN 00278424 (ISSN)
Hannon, G. J., Chubb, A., Maroney, P. A., Hannon, G., Altman, S., Nilsen, T. W. (1991) Multiple cis-acting elements are required for RNA polymerase III transcription of the gene encoding H1 RNA, the RNA component of human RNase P. Journal of Biological Chemistry, 266 (34). pp. 22796-22799. ISSN 00219258 (ISSN)
Hao, L. N., Tiganis, T., Tonks, N. K., Charbonneau, H. (November 1997) The noncatalytic C-terminal segment of the T cell protein tyrosine phosphatase regulates activity via an intramolecular mechanism. Journal of Biological Chemistry, 272 (46). pp. 29322-29329. ISSN 0021-9258
Harrington, R. J., Gutch, M. J., Hengartner, M. O., Tonks, N. K., Chisholm, A. D. (May 2002) The C-elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis. Development, 129 (9). pp. 2141-2153. ISSN 0950-1991
He, Shuning, Krens, Sf Gabby, Zhan, Huiqing, Gong, Zhiyuan, Hogendoorn, Pancras Cw, Spaink, Herman P, Snaar-Jagalska, B Ewa (September 2011) A ΔRaf1-ER-inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures. Journal of Pathology, 225 (1). pp. 19-28. ISSN 0022-3417
Hein, N., Bywater, M. J., Stanley, K., Verbrugge, I., Cullinane, C., Baker, A., Zuber, H., Rappaport, A., Drygin, D., Huser, N., Bliesath, J., Ryckman, D. M., Rice, W. G., Lowe, S. W., Johnstone, R. W., Pearson, R. B., McArthur, G. A., Hannan, R. D. (November 2011) Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias. Blood, 118 (21). p. 1548. ISSN 0006-4971
Hemmings, B. A., Restuccia, D., Tonks, N. K. (April 2009) Targeting the Kinome II. Curr Opin Cell Biol, 21 (2). pp. 135-139.
Hengartner, M. (August 1998) Apoptosis. Death by crowd control. Science, 281 (5381). pp. 1298-9. ISSN 0036-8075 (Print)
Henn, F. A., Anderson, D. J., Sellstrom, A. (1977) Possible relationship between glial cells, dopamine and the effects of antipsychotic drugs. Nature, 266 (5603). pp. 637-8.
Hershlag, A., Peyser, A., Bristow, S. L., Puig, O., Pollock, A., Niknazar, M., Mills, A. A. (December 2019) The potential impact of tumor suppressor genes on human gametogenesis: a case-control study. J Assist Reprod Genet. ISSN 1058-0468
Hinton, S. D., Myers, M. P., Roggero, V. R., Allison, L. A., Tonks, N. K. (May 2010) The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation. Biochemical Journal, 427. pp. 349-357. ISSN 0264-6021
Hinton, S. D., Yang, D. Z., Eckberg, W. R. (October 2003) Protein tyrosine phosphatases in Chaetopterus egg activation. Development Growth & Differentiation, 45 (5-6). pp. 405-415. ISSN 0012-1592
Hoffmann, Markus, Hofmann-Winkler, Heike, Smith, Joan C, Krüger, Nadine, Arora, Prerna, Sørensen, Lambert K, Søgaard, Ole S, Hasselstrøm, Jørgen Bo, Winkler, Michael, Hempel, Tim, Raich, Lluís, Olsson, Simon, Danov, Olga, Jonigk, Danny, Yamazoe, Takashi, Yamatsuta, Katsura, Mizuno, Hirotaka, Ludwig, Stephan, Noé, Frank, Kjolby, Mads, Braun, Armin, Sheltzer, Jason M, Pöhlmann, Stefan (March 2021) Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine, 65. p. 103255. ISSN 2352-3964
Hossain, Manzar, Bhalla, Kuhulika, Stillman, Bruce (March 2021) Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication. Molecular Cell. ISSN 1097-2765
Hsu, H. C., Wang, C. L., Wang, M., Yang, N., Chen, Z., Sternglanz, R., Xu, R. M. (January 2013) Structural basis for allosteric stimulation of Sir2 activity by sir4 binding. Genes and Development, 27 (1). pp. 64-73. ISSN 08909369
Hu, P., Wu, S., Hernandez, N. (September 2003) A minimal RNA polymerase III transcription system from human cells reveals positive and negative regulatory roles for CK2. Molecular Cell, 12 (3). pp. 699-709. ISSN 1097-2765
Hu, P., Wu, S., Sun, Y. L., Yuan, C. C., Kobayashi, R., Myers, M. P., Hernandez, N. (November 2002) Characterization of human RNA polymerase III identifies orthologues for Saccharomyces cerevisiae RNA polymerase III subunits. Molecular and Cellular Biology, 22 (22). pp. 8044-8055. ISSN 0270-7306
Hu, P., Wu, S., Sun, Y. L., Yuan, C. C., Kobayashi, R., Myers, M. P., Hernandez, N. (March 2003) A minimal RNA polymerase III transcription system from higher eucaryotic cells. Faseb Journal, 17 (5). A1185-A1185. ISSN 0892-6638
Huang, Z. J. (May 2009) Activity-dependent development of inhibitory synapses and innervation pattern: role of GABA signalling and beyond. Journal of Physiology-London, 587 (9). pp. 1881-1888. ISSN 0022-3751
Hyun, S. W., Sui, X., Del Vecchio, R. L., Tonks, N. K., Passaniti, A., Goldblum, S. E. (November 2004) Protein tyrosine phosphatase (PTP) mu regulates endothelial cell (EC) proliferation, adhesion and migration. Molecular Biology of the Cell, 15. 226A-226A. ISSN 1059-1524
Hörmann, A., Hopfgartner, B., Köcher, T., Corcokovic, M., Krammer, T., Reiser, C., Bader, G., Shi, J., Ehrenhöfer, K., Wöhrle, S., Schweifer, N., Vakoc, C. R., Kraut, N., Pearson, M., Petronczki, M., Neumüller, R. A. (June 2018) RIOK1 kinase activity is required for cell survival irrespective of MTAP status. Oncotarget, 9 (47). pp. 28625-28637. ISSN 1949-2553
I
Itoh, H., Takahashi, A., Adachi, K., Noji, H., Yasuda, R., Yoshida, M., Kinosita, K. (January 2004) Mechanically driven ATP synthesis by F-1-ATPase. Nature, 427 (6973). pp. 465-468. ISSN 0028-0836
J
Jacinto, E., Guo, B., Arndt, K. T., Schmelzle, T., Hall, M. N. (November 2001) TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. Molecular Cell, 8 (5). pp. 1017-1026. ISSN 1097-2765
Janas, J. A., Van Aelst, L. (May 2011) Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Molecular and Cellular Biology, 31 (13). pp. 2552-2565. ISSN 0270-7306
Javelle, M., Vernoud, V., Depège-Fargeix, N., Arnould, C., Oursel, D., Domergue, F., Sarda, X., Rogowsky, P. M. (2010) Overexpression of the epidermis-specific homeodomain-leucine zipper IV transcription factor OUTER CELL LAYER1 in maize identifies target genes involved in lipid metabolism and cuticle biosynthesis. Plant Physiology, 154 (1). pp. 273-286.
Jia, Z. C., Barford, D., Flint, A. J., Tonks, N. K. (June 1995) Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268 (5218). pp. 1754-1758. ISSN 0036-8075
Joneson, T., McDonough, M., Bar-Sagi, D., Van Aelst, L. (November 1996) RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science, 274 (5291). pp. 1374-1376. ISSN 0036-8075
Joshua-Tor, L., Johnston, S. A. (1998) The Bleomycin Hydrolases. In: Handbook of Proteolytic Enzymes. Elsevier Academic Press, London, pp. 634-638. ISBN 9780120796120
Juarez, J. C., Manuia, M., Burnett, M. E., Betancourt, O., Boivin, B., Shaw, D. E., Tonks, N. K., Mazar, A. P., Donate, F. (May 2008) Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling. Proc Natl Acad Sci U S A, 105 (20). pp. 7147-7152. ISSN 0027-8424
Jung, S. K., Jeong, D. G., Chung, S. J., Kim, J. H., Park, B. C., Tonks, N. K., Ryu, S. E., Kim, S. J. (February 2010) Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor. FASEB J., 24 (2). pp. 560-569. ISSN 0892-6638
K
Kamoun, Malek, Filali, Mohammed, Murray, Michael V., Awasthi, Sita, Wadzinski, Brian E. (October 2013) Protein phosphatase 2A family members (PP2A and PP6) associate with U1 snRNP and the spliceosome during pre-mRNA splicing. Biochemical and Biophysical Research Communications, 440 (2). pp. 306-311. ISSN 0006-291X
Kannan, N., Neuwald, A. F. (May 2004) Evolutionary clues to protein kinase structural mechanisms. Faseb Journal, 18 (8). C189-C189. ISSN 0892-6638
Kass-Eisler, A., Greider, C. W. (April 2000) Recombination in telomere-length maintenance. Trends in Biochemical Sciences, 25 (4). pp. 200-206. ISSN 0968-0004
Kataoka, T., Broek, D., Wigler, M. H. (December 1985) DNA sequence and characterization of the S. cerevisiae gene encoding adenylate cyclase. Cell, 43 (2). pp. 493-505. ISSN 0092-8674
Kato, H., Goto, D. B., Martienssen, R. A., Urano, T., Furukawa, K., Murakami, Y. (2005) RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Science, 309 (5733). pp. 467-469. ISSN 00368075 (ISSN)
Katt, W. P., Lukey, M. J., Cerione, R. A. (January 2017) A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis. Future Med Chem, 9 (2). pp. 223-243. ISSN 1756-8927
Kaufmann, B. P. (April 1949) Enzymatic studies of cellular organization. Science, 109 (2835). p. 443. ISSN 0036-8075 (Print)0036-8075 (Linking)
Kaufmann, B. P., Gay, H., McDonald, M. R. (1950) Localization of cellular proteins by enzymatic hydrolysis. Cold Spring Harb Symp Quant Biol, 14. pp. 85-91. ISSN 0091-7451 (Print)0091-7451 (Linking)
Kaufmann, B. P., McDonald, M. R., Gay, H. (July 1951) The distribution and interrelation of nucleic acids in fixed cells as shown by enzymatic hydrolysis. J Cell Physiol Suppl, 38 (Suppl.). pp. 71-99. ISSN 0737-1462 (Print)0737-1462 (Linking)
Kaufmann, Berwind Petersen (April 1948) Enzymatic studies of cellular organization. Science, 109 (2835). pp. 443-444. ISSN 0036-8075 (Print)0036-8075 (Linking)
Kaufmann, Berwind Petersen (1950) An evaluation of the applicability in cytochemical studies of methods involving enzymatic hydrolysis of cellular materials. Portugaliae acta biologica. 813-830, and two plates.
Kaufmann, Berwind Petersen, Gay, Helen, McDonald, Margaret R. (January 1950) Analysis of cell structure by digestion with enzymes. Genetics, 35 (1). pp. 117-118.
Kaufmann, Berwind Petersen, Gay, Helen, McDonald, Margaret R. (December 1948) Enzymatic degradation of plant chromosomes. American Journal of Botany, 35 (10). p. 794.
Kaufmann, Berwind Petersen, Gay, Helen, McDonald, Margaret R. (April 1951) Enzymatic degradation of ribonucleoproteins. American Journal of Botany, 38 (4). pp. 268-275.
Kawamukai, M., Ferguson, K., Wigler, M. H., Young, D. (February 1991) Genetic and biochemical analysis of the adenylyl cyclase of Schizosaccharomyces pombe. Cell Regulation, 2 (2). pp. 155-64. ISSN 1044-2030
Kim, S., Telo-Ruiz, M., Yin, J., Wodarz, A. (March 2003) Functional analysis of atypical protein kinase C in Drosophila oogenesis. European Journal of Cell Biology, 82 (S53). p. 83. ISSN 0171-9335
King, Bryan, Trimarchi, Thomas, Reavie, Linsey, Xu, Luyao, Mullenders, Jasper, Ntziachristos, Panagiotis, Aranda-Orgilles, Beatriz, Perez-Garcia, Arianne, Shi, Junwei, Vakoc, Christopher, Sandy, Peter, Shen, Steven S, Ferrando, Adolfo, Aifantis, Iannis (June 2013) The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability. Cell, 153 (7). pp. 1552-1566. ISSN 0092-8674
Koizumi, J., Okamoto, Y., Onogi, H., Mayeda, A., Krainer, A. R., Hagiwara, M. (April 1999) The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs). Journal of Biological Chemistry, 274 (16). pp. 11125-11131. ISSN 0021-9258
Kondo, S., Lu, Y., Debbas, M., Lin, A. W., Sarosi, I., Itie, A., Wakeham, A., Tuan, J., Saris, C., Elliott, G., Ma, W. L., Benchimol, S., Lowe, S. W., Mak, T. W., Thukral, S. K. (April 2003) Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). Proceedings of the National Academy of Sciences of the United States of America, 100 (9). pp. 5431-5436. ISSN 0027-8424
Krasnov, P., Michurina, T. V., Packer, M. A., Stasiv, Y., Nakaya, N., Moore, K. A., Drazan, K. E., Enikolopov, G. N. (March 2008) Neuronal nitric oxide synthase contributes to the regulation of hematopoiesis. Molecular Medicine, 14 (3-4). pp. 141-149. ISSN 1076-1551
Krishnan, N. (November 2012) Regulation of Protein Tyrsoine Phosphatase by Hydrogen Sulfide. Free Radical Biology and Medicine, 53 (Supple). S33-S33. ISSN 0891-5849
Krishnan, N., Fu, C., Pappin, D. J., Tonks, N. K. (2011) H2S-induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response. Science Signaling, 4 (203). ISSN 19450877 (ISSN)
Krishnan, N., Jeong, D. G., Jung, S.-k., Ryu, S. E., Xiao, A., Allis, C. D., Kim, S. J., Tonks, N. K. (June 2009) Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent. Journal of Biological Chemistry, 284 (24). pp. 16066-16070.
Kuhn, C. D., Wilusz, J. E., Zheng, Y., Beal, P. A., Joshua-Tor, L. (January 2015) On-Enzyme Refolding Permits Small RNA and tRNA Surveillance by the CCA-Adding Enzyme. Cell, 160 (4). pp. 644-658. ISSN 0092-8674 (Public Dataset)
Kuhn, C. D., Wilusz, J. E., Zheng, Y., Beal, P. A., Joshua-Tor, L. (July 2015) On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme. Febs Journal, 282 (Supple). p. 37. ISSN 1742-464X
Kumar, S., Sun, X., Sharma, S., Aggarwal, S., R., Kandasamy, Fineman, J. R., Black, S. M. (August 2009) GTP cyclohydrolase I expression is regulated by nitric oxide: role of cyclic AMP. Am J Physiol Lung Cell Mol Physiol, 297 (2). L309-317.
Kurland, J. F., Tansey, W. P. (May 2008) Myc-mediated transcriptional repression by recruitment of histone deacetylase. Cancer Res, 68 (10). pp. 3624-9.
L
La Montagne, K. R., Flint, A. J., Franza, B. R., Pendergast, A. M., Tonks, N. K. (May 1998) Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo. Molecular and Cellular Biology, 18 (5). pp. 2965-2975. ISSN 0270-7306
La Montagne, K. R., Pendergast, A. M., Franza, B. R., Tonks, N. K. (January 1995) Enhanced expression of a protein-tyrosine phosphatase in cells expressing P210BCR/ABL. Journal of Cellular Biochemistry. p. 65. ISSN 0730-2312
LaMontagne, K. R., Hannon, G., Tonks, N. K. (November 1998) Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells. Proceedings of the National Academy of Sciences of the United States of America, 95 (24). pp. 14094-14099. ISSN 0027-8424
Lam, M. H. C., Michell, B. J., Fodero-Tavoletti, M. T., Kemp, B. E., Tonks, N. K., Tiganis, T. (October 2001) Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase TCPTP. Journal of Biological Chemistry, 276 (40). pp. 37700-37707. ISSN 0021-9258
Laubscher, Dominik, Gryder, Berkley E, Sunkel, Benjamin D, Andresson, Thorkell, Wachtel, Marco, Das, Sudipto, Roschitzki, Bernd, Wolski, Witold, Wu, Xiaoli S, Chou, Hsien-Chao, Song, Young K, Wang, Chaoyu, Wei, Jun S, Wang, Meng, Wen, Xinyu, Ngo, Quy Ai, Marques, Joana G, Vakoc, Christopher R, Schäfer, Beat W, Stanton, Benjamin Z, Khan, Javed (November 2021) BAF complexes drive proliferation and block myogenic differentiation in fusion-positive rhabdomyosarcoma. Nature Communications, 12 (1). p. 6924. ISSN 2041-1723
Lazarus, O., Woolerton, T. W., Parkin, A., Lukey, M. J., Reisner, E., Seravalli, J., Pierce, E., Ragsdale, S. W., Sargent, F., Armstrong, F. A. (October 2009) Water-gas shift reaction catalyzed by redox enzymes on conducting graphite platelets. J Am Chem Soc, 131 (40). pp. 14154-5. ISSN 1520-5126
Lazebnik, Y. A., Kaufmann, S. H., Desnoyers, S., Poirier, G. G., Earnshaw, W. C. (1994) Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature, 371 (6495). pp. 346-347. ISSN 0028-0836
Lee, C. S., Lee, L. C., Yuan, T. L., Chakka, S., Fellmann, C., Lowe, S. W., Caplen, N. J., McCormick, F., Luo, J. (February 2019) MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival. Proc Natl Acad Sci U S A, 116 (10). pp. 4508-4517. ISSN 0027-8424
Lee, S. J., Lee, S. K., Yoon, H. J., Lee, H. H., Kim, K. K., Lee, B. J., Il Lee, B., Suh, S. W. (July 2012) Structures of Staphylococcus aureus peptide deformylase in complex with two classes of new inhibitors. Acta Crystallographica Section D-Biological Crystallography, 68 (Part 7). pp. 784-793. ISSN 0907-4449
Lee, S. J., Syed, S., Enemark, E. J., Schuck, S., Stenlund, A., Ha, T., Joshua-Tor, L. (March 2014) Dynamic look at DNA unwinding by a replicative helicase. Proceedings of the National Academy of Sciences of the United States of America, 111 (9). E827-35. ISSN 0027-8424
Lessard, L., Labbé, D. P., Deblois, G., Beǵin, L. R., Hardy, S., Mes-Masson, A. M., Saad, F., Trotman, L. C., Giguére, V., Tremblay, M. L. (March 2012) PTP1B is an androgen receptor-regulated phosphatase that promotes the progression of prostate cancer. Cancer Research, 72 (6). pp. 1529-1537. ISSN 00085472 (ISSN)
Leung, A., Geng, F., Daulny, A., Collins, G. A., Guzzardo, P. M., Tansey, W. P. (2008) Transcriptional control and the ubiquitin-proteasome system. Ernst Schering Found Symp Proc (1). pp. 75-97.
Li, Zhen, Huang, Xiaoqian, Zhan, Huiqing, Zeng, Zhiqiang, Li, Caixia, Spitsbergen, Jan M, Meierjohann, Svenja, Schartl, Manfred, Gong, Zhiyuan (February 2012) Inducible and repressable oncogene-addicted hepatocellular carcinoma in Tet-on xmrk transgenic zebrafish. Journal of Hepatology, 56 (2). pp. 419-425. ISSN 0168-8278
Li, F., Deng, Z., Zhang, L., Wu, C., Jin, Y., Hwang, I., Vladimirova, O., Xu, L., Yang, L., Lu, B., Dheekollu, J., Li, J. Y., Feng, H., Hu, J., Vakoc, C. R., Ying, H., Paik, J., Lieberman, P. M., Zheng, H. (August 2019) ATRX loss induces telomere dysfunction and necessitates induction of alternative lengthening of telomeres during human cell immortalization. Embo j, 38 (19). e96659. ISSN 0261-4189
Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., Parsons, R. (December 1998) The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Research, 58 (24). pp. 5667-5672. ISSN 0008-5472
Li, K., Zhou, T., Liao, L., Yang, Z., Wong, C., Henn, F., Malinow, R., Yates Iii, J. R., Hu, H. (August 2013) βCaMKII in lateral habenula mediates core symptoms of depression. Science, 341 (6149). pp. 1016-1020. ISSN 00368075 (ISSN)
Li, Y., Brooks, M., Yeoh-Wang, J., McCoy, R. M., Rock, T. M., Pasquino, A., Moon, C. I., Patrick, R. M., Tanurdzic, M., Ruffel, S., Widhalm, J. R., McCombie, W. R., Coruzzi, G. M. (October 2019) SDG8-mediated histone methylation and RNA processing function in the response to nitrate signaling. Plant Physiol. ISSN 0032-0889
Li, Bing, An, Wenbin, Wang, Hua, Baslan, Timour, Mowla, Shoron, Krishnan, Aishwarya, Xiao, Wenbin, Koche, Richard Patrick, Liu, Ying, Cai, Sheng F, Xiao, Zhijian, Derkach, Andriy, Iacobucci, Ilaria, Mullighan, Charles G, Helin, Kristian, Lowe, Scott W, Levine, Ross L, Rampal, Raajit K (April 2022) BMP2/SMAD pathway activation in JAK2/p53-mutant Megakaryocyte/Erythroid Progenitors Promotes Leukemic Transformation. Blood. ISSN 0006-4971
Li, Xiang, Huang, Chun-Hao, Sánchez-Rivera, Francisco J, Kennedy, Margaret C, Tschaharganeh, Darjus F, Morris, John P, Montinaro, Antonella, O'Rourke, Kevin P, Banito, Ana, Wilkinson, John E, Chen, Chi-Chao, Ho, Yu-Jui, Dow, Lukas E, Tian, Sha, Luan, Wei, de Stanchina, Elisa, Zhang, Tinghu, Gray, Nathanael S, Walczak, Henning, Lowe, Scott W (April 2022) A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets. Proceedings of the National Academy of Sciences of USA, 119 (17). e2110557119. ISSN 0027-8424
Li, Zhengnian, Ishida, Ryosuke, Liu, Yan, Wang, Jinhua, Li, Yina, Gao, Yang, Jiang, Jie, Che, Jianwei, Sheltzer, Jason M, Robers, Matthew B, Zhang, Tinghu, Westover, Kenneth D, Nabet, Behnam, Gray, Nathanael S (May 2022) Synthesis and Structure-Activity relationships of cyclin-dependent kinase 11 inhibitors based on a diaminothiazole scaffold. European Journal of Medicinal Chemistry, 238. p. 114433. ISSN 0223-5234
Lin, A., Giuliano, C. J., Palladino, A., John, K. M., Abramowicz, C., Yuan, M. L., Sausville, E. L., Lukow, D. A., Liu, L., Chait, A. R., Galluzzo, Z. C., Tucker, C., Sheltzer, J. M. (September 2019) Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials. Sci Transl Med, 11 (509). ISSN 1946-6234
Lin, A. W., Barradas, M., Stone, J. C., Van Aelst, L., Serrano, M., Lowe, S. W. (October 1998) Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes & Development, 12 (19). pp. 3008-3019. ISSN 0890-9369
Lin, G., Aranda, V., Muthuswamy, S. K., Tonks, N. K. (July 2011) Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'. Genes & Development, 25 (13). pp. 1412-1425. ISSN 0890-9369
Lindbäck, Louise N, Hu, Yuzhao, Ackermann, Amanda, Artz, Oliver, Pedmale, Ullas V (June 2022) UBP12 and UBP13 deubiquitinases destabilize the CRY2 blue light receptor to regulate Arabidopsis growth. Current Biology. ISSN 0960-9822
Lindtner, C., Scherer, T., Zielinski, E., Filatova, N., Fasshauer, M., Tonks, N. K., Puchowicz, M., Buettner, C. (January 2013) Binge Drinking Induces Whole-Body Insulin Resistance by Impairing Hypothalamic Insulin Action. Science Translational Medicine, 5 (170). ISSN 1946-6234
Liu, P. H., Shah, R. B., Li, Y., Arora, A., Ung, P. M., Raman, R., Gorbatenko, A., Kozono, S., Zhou, X. Z., Brechin, V., Barbaro, J. M., Thompson, R., White, R. M., Aguirre-Ghiso, J. A., Heymach, J. V., Lu, K. P., Silva, J. M., Panageas, K. S., Schlessinger, A., Maki, R. G., Skinner, H. D., de Stanchina, E., Sidi, S. (January 2019) An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy. Nat Cell Biol, 21 (2). pp. 203-213. ISSN 1465-7392
Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B. J., Skiba, B., Ooms, L. M., Stepto, N., Wu, B., Mitchell, C. A., Tonks, N. K., Watt, M. J., Febbraio, M. A., Crack, P. J., Andrikopoulos, S., Tiganis, T. (October 2009) Reactive Oxygen Species Enhance Insulin Sensitivity. Cell Metabolism, 10 (4). pp. 260-272.
Londhe, A. D., Bergeron, A., Curley, S. M., Zhang, F., Rivera, K. D., Kannan, A., Coulis, G., Rizvi, S. H. M., Kim, S. J., Pappin, D. J., Tonks, N. K., Linhardt, R. J., Boivin, B. (December 2019) Regulation of PTP1B activation through disruption of redox-complex formation. Nat Chem Biol, 16 (2). pp. 122-125. ISSN 1552-4450
Lou, Y.-W., Chen, Y.-Y., Hsu, S.-F., Chen, R.-K., Lee, C.-L., Khoo, K.-H., Tonks, N. K., Meng, T.-C. (January 2008) Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells. FEBS Journal, 275 (1). pp. 69-88.
Lowe, S. W., Sherr, C. J. (February 2003) Tumor suppression by Ink4a-Arf: progress and puzzles. Current Opinion in Genetics & Development, 13 (1). pp. 77-83. ISSN 0959-437X
Luckett, Kathleen A, Cracchiolo, Jennifer R, Krishnamoorthy, Gnana P, Leandro-Garcia, Luis Javier, Nagarajah, James, Saqcena, Mahesh, Lester, Rona, Im, Soo Y, Zhao, Zhen, Lowe, Scott W, de Stanchina, Elisa, Sherman, Eric J, Ho, Alan L, Leach, Steven D, Knauf, Jeffrey A, Fagin, James A (May 2021) Co-inhibition of SMAD and MAPK signaling enhances 124I uptake in BRAF-mutant thyroid cancers. Endocrine-Related Cancer, 28 (6). pp. 391-402. ISSN 1351-0088
Lukey, M. J., Parkin, A., Roessler, M. M., Murphy, B. J., Harmer, J., Palmer, T., Sargent, F., Armstrong, F. A. (February 2010) How Escherichia coli is equipped to oxidize hydrogen under different redox conditions. J Biol Chem, 285 (6). pp. 3928-38. ISSN 1083-351X (Public Dataset)
Lydeard, J. R., Lipkin-Moore, Z., Sheu, Y. J., Stillman, B., Burgers, P. M., Haber, J. E. (2010) Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly. Genes and Development, 24 (11). pp. 1133-1144.
M
Ma, Wai Kit, Voss, Dillon M, Scharner, Juergen, Costa, Ana SH, Lin, Kuang-Ting, Jeon, Hyun Yong, Wilkinson, John E, Jackson, Michaela, Rigo, Frank, Bennett, C Frank, Krainer, Adrian R (December 2021) ASO-based PKM splice-switching therapy inhibits hepatocellular carcinoma growth. Cancer Research. canres.0948.2020-canres.0948.2020. ISSN 0008-5472
MacKintosh, C., Garton, A. J., McDonnell, A., Barford, D., Cohen, P. T. W., Tonks, N. K., Cohen, P. (November 1996) Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation. Febs Letters, 397 (2-3). pp. 235-238. ISSN 0014-5793
Malone, T., Blumenthal, R. M., Cheng, X. (November 1995) Structure-guided analysis reveals nine sequence motifs conserved among DNA amino-methyltransferases, and suggests a catalytic mechanism for these enzymes. J Mol Biol, 253 (4). pp. 618-32. ISSN 0022-2836 (Print)
Mangel, W. F., Singer, P. T., Cyr, D. M., Umland, T. C., Toledo, D. L., Stroud, R. M., Pflugrath, J. W., Sweet, R. M. (September 1990) Structure of an acyl-enzyme intermediate during catalysis: (guanidinobenzoyl)trypsin. Biochemistry, 29 (36). pp. 8351-7. ISSN 0006-2960 (Print)0006-2960 (Linking)
Martinez, M. A. Q., Kinney, B. A., Medwig-Kinney, T. N., Ashley, G., Ragle, J. M., Johnson, L., Aguilera, J., Hammell, C. M., Ward, J. D., Matus, D. Q. (January 2020) Rapid Degradation of Caenorhabditis elegans Proteins at Single-Cell Resolution with a Synthetic Auxin. G3 (Bethesda, Md.), 10 (1). pp. 267-280. ISSN 21601836 (ISSN) (Public Dataset)
Mattick, John S, Amaral, Paulo P, Carninci, Piero, Carpenter, Susan, Chang, Howard Y, Chen, Ling-Ling, Chen, Runsheng, Dean, Caroline, Dinger, Marcel E, Fitzgerald, Katherine A, Gingeras, Thomas R, Guttman, Mitchell, Hirose, Tetsuro, Huarte, Maite, Johnson, Rory, Kanduri, Chandrasekhar, Kapranov, Philipp, Lawrence, Jeanne B, Lee, Jeannie T, Mendell, Joshua T, Mercer, Timothy R, Moore, Kathryn J, Nakagawa, Shinichi, Rinn, John L, Spector, David L, Ulitsky, Igor, Wan, Yue, Wilusz, Jeremy E, Wu, Mian (January 2023) Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews Molecular Cell Biology. ISSN 1471-0072
McGuire, M. C., Fields, R. M., Nyomba, B. L., Raz, I., Bogardus, C., Tonks, N. K., Sommercorn, J. (July 1991) Abnormal regulation of protein tyrosine phosphatase activities in skeletal muscle of insulin-resistant humans. Diabetes, 40 (7). pp. 939-942. ISSN 0012-1797
Meng, T. C., Fukada, T., Tonks, N. K. (February 2002) Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Molecular Cell, 9 (2). pp. 387-399. ISSN 1097-2765
Meng, T. C., Hsu, S. F., Tonks, N. K. (January 2005) Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo. Methods, 35 (1). pp. 28-36. ISSN 1046-2023
Meng, T. C., Tonks, N. K. (2003) Analysis of the regulation of protein tyrosine phosphatases in vivo by reversible oxidation. In: Protein Phosphatases. Methods in Enzymology, 366 . Academic Press Inc, San Diego, pp. 304-318. ISBN 0076-6879
Merrill, Joseph R, Inguscio, Alessandra, Chung, Taemoon, Demestichas, Breanna, Garcia, Libia A, Habel, Jill, Lewis, David Y, Janowitz, Tobias, Lyons, Scott K (August 2023) Sensitive, non-immunogenic in vivo imaging of cancer metastases and immunotherapy response. Cell Stress, 7 (8). pp. 59-68. ISSN 2523-0204
Mertens, C., Hofmann, I., Wang, Z. X., Teichmann, M., Chong, S. S., Schnolzer, M., Franke, W. W. (July 2001) Nuclear particles containing RNA polymerase III complexes associated with the junctional plaque protein plakophilin 2. Proceedings of the National Academy of Sciences of the United States of America, 98 (14). pp. 7795-7800. ISSN 0027-8424
Meze, Katarina, Axhemi, Armend, Thomas, Dennis, Doymaz, Ahmet, Joshua-Tor, Leemor (2021) A shape-shifting nuclease unravels structured RNA. bioRxiv. (Submitted)
Mikhailik, Anatoly, Michurina, Tatyana V, Dikranian, Krikor, Hearn, Stephen, Maxakov, Vladimir I, Siller, Saul S, Takemaru, Ken-Ichi, Enikolopov, Grigori, Peunova, Natalia (May 2021) nNOS regulates ciliated cell polarity, ciliary beat frequency, and directional flow in mouse trachea. Life science alliance, 4 (5). ISSN 2575-1077
Min, J. R., Zhang, X., Cheng, X. D., Grewal, S. I. S., Xu, R. M. (November 2002) Structure of the SET domain histone lysine methyltransferase Clr4. Nature Structural Biology, 9 (11). pp. 828-832. ISSN 1072-8368
Minshull, J., Sun, H., Tonks, N. K., Murray, A. W. (November 1994) A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts. Cell, 79 (3). pp. 475-486. ISSN 0092-8674
Mo, Yan, Duan, Shoufu, Zhang, Xu, Hua, Xu, Zhou, Hui, Wei, Hong-Jian, Watanabe, Jun, McQuillan, Nicholas, Su, Zhenyi, Gu, Wei, Wu, Cheng-Chia, Vakoc, Christopher R, Hashizume, Rintaro, Chang, Kenneth, Zhang, Zhiguo (October 2022) Epigenome programing by H3.3K27M mutation creates a dependence of pediatric glioma on SMARCA4. Cancer Discovery. CD-21. ISSN 2159-8274
Monaghan, C., Holland, S., Dale, J. W. (1982) The Interaction of Anthra Quinone Dyes with the Plasmid Mediated Oxa-2 Beta Lactamase Ec-3.5.2.6. Biochemical Journal, 205 (2). pp. 413-418.
Mondol, A. S., Tonks, N. K., Kamata, T. (February 2014) Nox4 redox regulation of PTP1B contributes to the proliferation and migration of glioblastoma cells by modulating tyrosine phosphorylation of coronin-1C. Free Radical Biology and Medicine, 67. pp. 285-91. ISSN 0891-5849
Moore, E. C., McDonald, Margaret R. (1955) The inactivation of dilute solutions of crystalline chymotrypsin by X-radiation. Radiation Research, 3 (1). pp. 38-43.
Moore, J. E., Purcaro, M. J., Pratt, H. E., Epstein, C. B., Shoresh, N., Adrian, J., Kawli, T., Davis, C. A., Dobin, A., Kaul, R., Halow, J., Van Nostrand, E. L., Freese, P., Gorkin, D. U., Shen, Y., He, Y., Mackiewicz, M., Pauli-Behn, F., Williams, B. A., Mortazavi, A., Keller, C. A., Zhang, X. O., Elhajjajy, S. I., Huey, J., Dickel, D. E., Snetkova, V., Wei, X., Wang, X., Rivera-Mulia, J. C., Rozowsky, J., Zhang, J., Chhetri, S. B., Zhang, J., Victorsen, A., White, K. P., Visel, A., Yeo, G. W., Burge, C. B., Lécuyer, E., Gilbert, D. M., Dekker, J., Rinn, J., Mendenhall, E. M., Ecker, J. R., Kellis, M., Klein, R. J., Noble, W. S., Kundaje, A., Guigó, R., Farnham, P. J., Cherry, J. M., Myers, R. M., Ren, B., Graveley, B. R., Gerstein, M. B., Pennacchio, L. A., Snyder, M. P., Bernstein, B. E., Wold, B., Hardison, R. C., Gingeras, T. R., Stamatoyannopoulos, J. A., Weng, Z. (July 2020) Expanded encyclopaedias of DNA elements in the human and mouse genomes. Nature, 583 (7818). pp. 699-710. ISSN 0028-0836 (Print)0028-0836
Muratani, Masafumi, Tansey, William P. (March 2003) How the ubiquitin-proteasome system controls transcription. Nature Reviews Molecular Cell Biology, 4 (3). pp. 192-201. ISSN 1471-0072
Myers, M. P., Andersen, J. N., Cheng, A., Tremblay, M. L., Horvath, C. M., Parisien, J. P., Salmeen, A., Barford, D., Tonks, N. K. (December 2001) TYK2 and JAR2 are substrates of protein-tyrosine phosphatase 1B. Journal of Biological Chemistry, 276 (51). pp. 47771-47774. ISSN 0021-9258
Myers, M. P., Tonks, N. K. (December 1997) PTEN: Sometimes taking it off can be better than putting it on. American Journal of Human Genetics, 61 (6). pp. 1234-1238. ISSN 0002-9297
N
Nakayama, J., Allshire, R. C., Klar, A. J. S., Grewal, S. I. S. (June 2001) Role for DNA polymerase alpha in epigenetic control of transcriptional silencing in fission yeast. Embo Journal, 20 (11). pp. 2857-2866. ISSN 0261-4189
Nakayama, J., Xiao, G., Noma, K., Malikzay, A., Bjerling, P., Ekwall, K., Kobayashi, R., Grewal, S. I. (June 2003) Alp13, an MRG family protein, is a component of fission yeast Clr6 histone deacetylase required for genomic integrity. Embo Journal, 22 (11). pp. 2776-87. ISSN 0261-4189
Nath, A., Koo, P. K., Rhoades, E., Atkins, W. M. (November 2008) Allosteric effects on substrate dissociation from cytochrome P450 3A4 in nanodiscs observed by ensemble and single-molecule fluorescence spectroscopy. J Am Chem Soc, 130 (47). pp. 15746-7. ISSN 0002-7863
Neel, B. G., Tonks, N. K. (April 1997) Protein tyrosine phosphatases in signal transduction. Current Opinion in Cell Biology, 9 (2). pp. 193-204. ISSN 0955-0674
Nelson, K., Meng, T. C., Tonks, N., Melendez, J. A. (2002) Mitochondrial H2O2 enhances matrix metalloproteinase expression by protein tyrosine phosphatase inactivation. Free Radical Biology and Medicine, 33. S355-S355. ISSN 0891-5849
Neuwald, A. F. (August 2003) Evolutionary clues to DNA polymerase III beta clamp structural mechanisms. Nucleic Acids Research, 31 (15). pp. 4503-4516. ISSN 0305-1048
Newbold, A., Bots, M., Cluse, L., Lindemann, R., Lowe, S. W., Richon, V., Secrist, P., Miller, T., Hardwick, J., Johnstone, R. (November 2010) Mechanisms of action of histone deacetylase inhibitors (HDACi). Ejc Supplements, 8 (7). p. 46. ISSN 1359-6349
Nielsen, B. S., Egeblad, M., Rank, F., Askautrud, H. A., Pennington, C. J., Pedersen, T. X., Christensen, I. J., Edwards, D. R., Werb, Z., Lund, L. R. (2008) Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression. PLoS One, 3 (8). ISSN 19326203 (ISSN)
Nikawa, J., Cameron, S., Toda, T., Ferguson, K. M., Wigler, M. H. (November 1987) Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae. Genes & Development, 1 (9). pp. 931-937.
Nikawa, J., Sass, P., Wigler, M. H. (October 1987) Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae. Molecular & Cellular Biology, 7 (10). pp. 3629-36. ISSN 0270-7306
Nilsson, C. E., Petersen-Mahrt, S., Durot, C., Shtrichman, R., Krainer, A. R., Kleinberger, T., Akusjarvi, G. (February 2001) The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins. EMBO Journal, 20 (4). pp. 864-871. ISSN 0261-4189
Nowack, Moritz K., Harashima, Hirofumi, Dissmeyer, Nico, Zhao, Xin'Ai, Bouyer, Daniel, Weimer, Annika K., De Winter, Freya, Yang, Fang, Schnittger, Arp (May 2012) Genetic Framework of Cyclin-Dependent Kinase Function in Arabidopsis. Developmental Cell, 22 (5). pp. 1030-1040. ISSN 1534-5807
O
Osten, P., Hrabetova, S., Sacktor, T. C. (1996) Differential downregulation of protein kinase C isoforms in spreading depression. Neuroscience Letters, 221 (1). pp. 37-40. ISSN 03043940 (ISSN)
Osterbaan, Larissa J, Hoyle, Victoria, Curtis, Michelle, DeBlasio, Stacy, Rivera, Keith D, Heck, Michelle, Fuchs, Marc (May 2021) Identification of protein interactions of grapevine fanleaf virus RNA-dependent RNA polymerase during infection of by affinity purification and tandem mass spectrometry. The Journal of general virology, 102 (5). ISSN 1465-2099
Ostman, A., Yang, Q., Tonks, N. K. (October 1994) Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density. Proceedings of the National Academy of Sciences of the United States of America, 91 (21). pp. 9680-9684. ISSN 0027-8424
P
Paine, I., Posey, J. E., Grochowski, C. M., Jhangiani, S. N., Rosenheck, S., Kleyner, R., Marmorale, T., Yoon, M., Wang, K., Robison, R., Cappuccio, G., Pinelli, M., Magli, A., Coban Akdemir, Z., Hui, J., Yeung, W. L., Wong, B. K. Y., Ortega, L., Bekheirnia, M. R., Bierhals, T., Hempel, M., Johannsen, J., Santer, R., Aktas, D., Alikasifoglu, M., Bozdogan, S., Aydin, H., Karaca, E., Bayram, Y., Ityel, H., Dorschner, M., White, J. J., Wilichowski, E., Wortmann, S. B., Casella, E. B., Kitajima, J. P., Kok, F., Monteiro, F., Muzny, D. M., Bamshad, M., Gibbs, R. A., Sutton, V. R., Van Esch, H., Brunetti-Pierri, N., Hildebrandt, F., Brautbar, A., Van den Veyver, I. B., Glass, I., Lessel, D., Lyon, G. J., Lupski, J. R. (June 2019) Paralog Studies Augment Gene Discovery: DDX and DHX Genes. Am J Hum Genet, 105 (2). pp. 302-316. ISSN 0002-9297
Palka, H. L., Park, M., Tonks, N. K. (February 2003) Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1. Journal of Biological Chemistry, 278 (8). pp. 5728-35. ISSN 0021-9258
Pannifer, A. D. B., Flint, A. J., Tonks, N. K., Barford, D. (April 1998) Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by X-ray crystallography. Journal of Biological Chemistry, 273 (17). pp. 10454-10462. ISSN 0021-9258
Park, C. Y., La Montagne, K. R., Tonks, N. K., Hayman, M. J. (October 1996) Cloning and expression of the chicken protein tyrosine phosphatase SH-PTP2. Gene, 177 (1-2). pp. 93-97. ISSN 0378-1119
Paul, Shilpi, Rebok, Abbey, Cifani, Paolo, Paul, Anirban, Pappin, Darryl, Huang, Tony, Spratt, Thomas (2022) Translesion DNA synthesis polymerase κ is essential to a carcinogen-induced nucleolar stress response. bioRxiv. (Submitted)
Paul, S., Kuo, A., Schalch, T., Vogel, H., Joshua-Tor, L., McCombie, W. R., Gozani, O., Hammell, M., Mills, A. A. (January 2013) Chd5 Requires PHD-Mediated Histone 3 Binding for Tumor Suppression. Cell Reports, 3 (1). pp. 92-102. ISSN 2211-1247 (Public Dataset)
Pavlovsky, A. G., Liu, X., Faehnle, C. R., Potente, N., Viola, R. E. (January 2012) Structural characterization of inhibitors with selectivity against members of a homologous enzyme family. Chemical Biology and Drug Design, 79 (1). pp. 128-136. ISSN 17470277 (ISSN)
Pawlak, G., Helfman, D. M. (July 2002) MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway. Journal of Biological Chemistry, 277 (30). pp. 26927-26933. ISSN 0021-9258
Perez, J. L., Khatri, L., Chang, C., Srivastava, S., Osten, P., Ziff, E. B. (2001) PICK1 targets activated protein kinase Cα to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. Journal of Neuroscience, 21 (15). pp. 5417-5428. ISSN 02706474 (ISSN)
Polyanskaya, Sofya A, Moreno, Rosamaria Y, Lu, Bin, Feng, Ruopeng, Yao, Yu, Irani, Seema, Klingbeil, Olaf, Yang, Zhaolin, Wei, Yiliang, Demerdash, Osama E, Benjamin, Lukas A, Weiss, Mitchell J, Zhang, Yan Jessie, Vakoc, Christopher R (January 2022) SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia. Cell Reports, 38 (2). p. 110233. ISSN 2211-1247
Potts, M., Sun, H., Mockaitis, K., Kennelly, P. J., Reed, D., Tonks, N. K. (April 1993) A protein-tyrosine/serine phosphatase encoded by the genome of the cyanobacterium Nostoc commune UTEX 584. Journal of Biological Chemistry, 268 (11). pp. 7632-7635. ISSN 0021-9258
Ptashne, M., Gann, A. (February 2003) Imposing specificity on kinases. Science, 299 (5609). pp. 1025-1027. ISSN 0036-8075
Q
Qian, Zhe, Song, Dongyan, Ipsaro, Jonathan J, Bautista, Carmelita, Joshua-Tor, Leemor, Yeh, Johannes T-H, Tonks, Nicholas K (September 2023) Manipulating PTPRD function with ectodomain antibodies. Genes and Development. ISSN 0890-9369
R
Rajah, Abira, Boudreau, Colton G, Ilie, Alina, Wee, Tse-Luen, Tang, Kaixi, Borisov, Aleksandar Z, Orlowski, John, Brown, Claire M (August 2019) Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX. Scientific Reports, 9 (1). p. 11430. ISSN 2045-2322
Ramachandran, C., Aebersold, R., Tonks, N. K., Pot, D. A. (May 1992) Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases. Biochemistry, 31 (17). pp. 4232-4238. ISSN 0006-2960
Rasko, T., Der, A., Klement, E., Slaska-Kiss, K., Posfai, E., Medzihradszky, K. F., Marshak, D. R., Roberts, R. J. , Kiss, A. (June 2010) BspRI restriction endonuclease: cloning, expression in Escherichia coli and sequential cleavage mechanism. Nucleic Acids Res, 38 (20). pp. 7155-7166. ISSN 1362-4962 (Electronic) 0305-1048 (Linking)
Revia, Steffie, Seretny, Agnieszka, Wendler, Lena, Banito, Ana, Eckert, Christoph, Breuer, Kersten, Mayakonda, Anand, Lutsik, Pavlo, Evert, Matthias, Ribback, Silvia, Gallage, Suchira, Chikh Bakri, Ismaiel, Breuhahn, Kai, Schirmacher, Peter, Heinrich, Stefan, Gaida, Matthias M, Heikenwälder, Mathias, Calvisi, Diego F, Plass, Christoph, Lowe, Scott W, Tschaharganeh, Darjus F (August 2022) Histone H3K27 demethylase KDM6A is an epigenetic gatekeeper of mTORC1 signalling in cancer. Gut, 71 (8). pp. 1613-1628. ISSN 0017-5749
Revyakin, A., Allemand, J. F., Croquette, V., Ebright, R. H., Strick, T. R. (2003) Single-molecule DNA nanomanipulation: Detection of promoter-unwinding events by RNA polymerase. In: Rna Polymerases and Associated Factors, Part C. Methods in Enzymology, 370 . Academic Press Inc, San Diego, pp. 577-598. ISBN 0076-6879
Revyakin, A. G., Ebright, R. H., Strick, T. R. (February 2003) Promoter melting by RNA polymerase: Detection and analysis by single-molecule DNA nanomanipulation. Biophysical Journal, 84 (2). 300A-300A. ISSN 0006-3495
Revyakin, A. G., Strick, T. R., Ebright, R. H. (January 2002) Promoter melting by RNA polymerase: Detection and analysis by single-molecule DNA nanomanipulation. Biophysical Journal, 82 (1). 115A-115A. ISSN 0006-3495
Roberts, R. J. (November 1978) Restriction and modification enzymes and their recognition sequences. Gene, 4 (3). pp. 183-94. ISSN 0378-1119 (Print)0378-1119 (Linking)
Roberts, R. J., Myers, P. A., Morrison, A., Murray, K. (May 1976) A specific endonuclease from Haemophilus haemolyticus. J Mol Biol, 103 (1). pp. 199-208.
Rossmann, M. P., Stillman, B. (July 2013) Immunoblotting histones from yeast whole-cell protein extracts. Cold Spring Harbor Protocols, 2013 (7). ISSN 1559-6095
Russell, S. J., Gonzalez, F., Joshua-Tor, L., Johnston, S. A. (October 2001) Selective chemical inactivation of AAA proteins reveals distinct functions of proteasomal ATPases. Chemistry & Biology, 8 (10). pp. 941-950. ISSN 1074-5521
Ruzinova, M. B., Schoer, R. A., Gerald, W., Egan, J. E., Pandolfi, P. P., Rafii, S., Manova, K., Mittal, V., Benezra, R. (October 2003) Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell, 4 (4). pp. 277-289. ISSN 1535-6108
S
Sabin, L. R., Zheng, Q., Thekkat, P., Yang, J., Hannon, G. J., Gregory, B. D., Tudor, M., Cherry, S. (February 2013) Dicer-2 Processes Diverse Viral RNA Species. PLoS ONE, 8 (2). ISSN 19326203 (ISSN)
Sacktor, T. C., Osten, P., Valsamis, H., Jiang, X., Naik, M. U., Sublette, E. (1993) Persistent activation of the ζ isoform of protein kinase C in the maintenance of long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America, 90 (18). pp. 8342-8346. ISSN 00278424 (ISSN)
Safaric Tepes, Polona, Pal, Debjani, Lindsted, Trine, Ibarra, Ingrid, Lujambio, Amaia, Jimenez Sabinina, Vilma, Senturk, Serif, Miller, Madison, Korimerla, Navya, Huang, Jiahao, Glassman, Lawrence, Lee, Paul, Zeltsman, David, Hyman, Kevin, Esposito, Michael, Hannon, Greg, Sordella, Raffaella (July 2021) An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating miR-335 expression. eLife, 10. ISSN 2050-084X
Salghetti, S. E., Kim, S. Y., Tansey, W. P. (February 1999) Destruction of Myc by ubiquitin-mediated proteolysis: cancer-associated and transforming mutations stabilize Myc. Embo Journal, 18 (3). pp. 717-26. ISSN 0261-4189 (Print)
Salmeen, A., Andersen, J. N., Myers, M. P., Meng, T. C., Hinks, J. A., Tonks, N. K., Barford, D. (June 2003) Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate. Nature, 423 (6941). pp. 769-773. ISSN 0028-0836
Schneider, B. L., Patton, E. E., Lanker, S., Mendenhall, M. D., Wittenberg, C., Futcher, B., Tyers, M. (September 1998) Yeast G1 cyclins are unstable in G1 phase. Nature, 395 (6697). pp. 86-9. ISSN 0028-0836 (Print)
Schneider, B. L., Steiner, B., Seufert, W., Futcher, A. B. (February 1996) pMPY-ZAP: a reusable polymerase chain reaction-directed gene disruption cassette for Saccharomyces cerevisiae. Yeast, 12 (2). pp. 129-34. ISSN 0749-503X (Print)
Schramm, L., Hernandez, N. (October 2002) Recruitment of RNA polymerase III to its target promoters. Genes & Development, 16 (20). pp. 2593-2620. ISSN 0890-9369
Schramm, L., Pendergrast, P. S., Sun, Y. L., Hernandez, N. (October 2000) Different human TFIIIB activities direct RNA polymerase III transcription from TATA-containing and TATA-less promoters. Genes & Development, 14 (20). pp. 2650-2663. ISSN 0890-9369
Schumann, G., Rujescu, D., Kissling, C., Soyka, M., Dahmen, N., Preuss, U. W., Wieman, S., Depner, M., Wellek, S., Lascorz, J., Bondy, B., Giegling, I., Anghelescu, I., Cowen, M. S., Poustka, A., Spanagel, R., Mann, K., Henn, F. A., Szegedi, A. (December 2003) Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts. Biol Psychiatry, 54 (12). pp. 1422-6. ISSN 0006-3223 (Print)0006-3223 (Linking)
Seger, Y. R., García-Cao, M., Piccinin, S., Lo Cunsolo, C., Doglioni, C., Blasco, M. A., Hannon, G. J., Maestro, R. (2002) Transformation of normal human cells in the absence of telomerase activation. Cancer Cell, 2 (5). pp. 401-413. ISSN 15356108 (ISSN)
Segovia, Danilo, Adams, Dexter W, Hoffman, Nickolas, Safaric Tepes, Polona, Wee, Tse-Luen, Cifani, Paolo, Joshua-Tor, Leemor, Krainer, Adrian R (May 2024) SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. Proceedings of the National Academy of Sciences of the United States of America, 121 (21). e2322974121. ISSN 0027-8424 (Public Dataset)
Sengupta, R., Sahoo, R., Mukherjee, S., Regulski, M., Tully, T., Stuehr, D. J., Ghosh, S. (June 2003) Characterization of Drosophila nitric oxide synthase: a biochemical study. Biochemical and Biophysical Research Communications, 306 (2). pp. 590-597. ISSN 0006-291X
Shakya, R., Reid, L. J., Reczek, C. R., Cole, F., Egli, D., Lin, C. S., DeRooij, D. G., Hirsch, S., Ravi, K., Hicks, J. B., Szabolcs, M., Jasin, M., Baer, R., Ludwig, T. (October 2011) BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity. Science, 334 (6055). pp. 525-528. ISSN 00368075 (ISSN)
Shao, M. H., Zheng, H. Q., Hu, Y., Liu, D. H., Jang, J. C., Ma, H., Huang, H. (October 2004) The GAOLAOZHUANGREN1 gene encodes a putative glycosyltransferase that is critical for normal development and carbohydrate metabolism. Plant and Cell Physiology, 45 (10). pp. 1453-1460. ISSN 0032-0781
Shen, Y., Luche, R., Wei, B., Gordon, M. L., Diltz, C. D., Tonks, N. K. (November 2001) Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1. Proceedings of the National Academy of Sciences of the United States of America, 98 (24). pp. 13613-13618. ISSN 0027-8424
Sheu, Y. J., Kinney, J. B., Lengronne, A., Pasero, P., Stillman, B. (April 2014) Domain within the helicase subunit Mcm4 integrates multiple kinase signals to control DNA replication initiation and fork progression. Proceedings of the National Academy of Sciences of the United States of America, 111 (18). E1899-1908. ISSN 0027-8424
Sheu, Y. J., Stillman, B. (January 2010) The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4. Nature, 463 (7277). pp. 113-117.
Sheu, Yi-Jun, Kawaguchi, Risa Karakida, Gillis, Jesse, Stillman, Bruce (December 2022) Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters. eLife, 11. e84320. ISSN 2050-084X (Public Dataset)
Shimabukuro, K., Yasuda, R., Muneyuki, E., Hara, K. Y., Kinosita, K., Yoshida, M. (December 2003) Catalysis and rotation of F-1 motor: Cleavage of ATP at the catalytic site occurs in 1 ms before 40 degrees substep rotation. Proceedings of the National Academy of Sciences of the United States of America, 100 (25). pp. 14731-14736. ISSN 0027-8424
Shineberg, B., Zipser, D. (December 1973) The ion gene and degradation of beta-galactosidase nonsense fragments. J Bacteriol, 116 (3). pp. 1469-71.
Siolas, D., Lerner, C., Burchard, J., Ge, W., Linsley, P. S., Paddison, P. J., Hannon, G. J., Cleary, M. A. (February 2005) Synthetic shRNAs as potent RNAi triggers. Nat Biotechnol, 23 (2). pp. 227-31. ISSN 1087-0156 (Print)
Smolen, G. A., Sordella, R., Muir, B., Mohapatra, G., Barmettler, A., Archibald, H., Kim, W. J., Okimoto, R. A., Bell, D. W., Sgroi, D. C., Christensen, J. G., Settleman, J., Haber, D. A. (February 2006) Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proceedings of the National Academy of Sciences of the United States of America, 103 (7). pp. 2316-21. ISSN 0027-8424
Sorida, M., Hirauchi, T., Ishizaki, H., Kaito, W., Shimada, A., Mori, C., Chikashige, Y., Hiraoka, Y., Suzuki, Y., Ohkawa, Y., Kato, H., Takahata, S., Murakami, Y. (June 2019) Regulation of ectopic heterochromatin-mediated epigenetic diversification by the JmjC family protein Epe1. PLoS Genet, 15 (6). e1008129. ISSN 1553-7390
Sounni, N. E., Dehne, K., Van Kempen, L., Egeblad, M., Affara, N. I., Cuevas, I., Wiesen, J., Junankar, S., Korets, L., Lee, J., Shen, J., Morrison, C. J., Overall, C. M., Krane, S. M., Werb, Z., Boudreau, N., Coussens, L. M. (March 2010) Stromal regulation of vessel stability by MMP14 and TGFbeta. Disease Models and Mechanisms, 3 (5-6). pp. 317-332. ISSN 17548403 (ISSN)
Srivastava, S., Swanson, S. K., Manel, N., Florens, L., Washburn, M. P., Skowronski, J. (May 2008) Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection. PLoS Pathog, 4 (5). e1000059.
Steger, D. J., Lefterova, M. I., Ying, L., Stonestrom, A. J., Schupp, M., Zhuo, D., Vakoc, A. L., Kim, J. E., Chen, J., Lazar, M. A., Blobel, G. A., Vakoc, C. R. (2008) DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Molecular and Cellular Biology, 28 (8). pp. 2825-2839. ISSN 02707306 (ISSN)
Stillman, Bruce (June 2024) Establishing a biochemical understanding of the initiation of chromosome replication in bacteria. Proceedings of the National Academy of Sciences of the United States of America, 121 (23). e2400667121. ISSN 0027-8424
Stover, D. R., Charbonneau, H., Tonks, N. K., Walsh, K. A. (September 1991) Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells. Proceedings of the National Academy of Sciences of the United States of America, 88 (17). pp. 7704-7707. ISSN 0027-8424
Strick, T. R., Charvin, G., Dekker, N. H., Allemand, J. F., Bensimon, D., Croquette, V. (June 2002) Tracking enzymatic steps of DNA topoisomerases using single-molecule micromanipulation. Comptes Rendus Physique, 3 (5). pp. 595-618. ISSN 1631-0705
Sublette, E., Naik, M. U., Jiang, X., Osten, P., Valsamis, H., Osada, S., Ohno, S., Sacktor, T. C. (1993) Evidence for a new, high-molecular weight isoform of protein kinase C in rat hippocampus. Neuroscience Letters, 159 (1-2). pp. 175-178. ISSN 03043940 (ISSN)
Sui, X., Hyun, S. W., Kiser, T. D., Del Vecchio, R. L., Tonks, N. K., Passaniti, A., Goldblum, S. E. (November 2004) Receptor protein tyrosine phosphatase (PTP) mu regulates the endothelial paracellular pathway. Molecular Biology of the Cell, 15. 428A-428A. ISSN 1059-1524
Sui, X., Kiser, T. D., Del Vecchio, R. L., Young, B. A., Gregoryev, D., Garcia, J. G. N., Tonks, N. K., Goldblum, S. E. (November 2001) PTP mu regulates the tyrosine phosphorylation state of VE-cadherin and the pulmonary microvascular endothelial paracellular pathway. Molecular Biology of the Cell, 12. 158A-158A. ISSN 1059-1524
Sulger, J., Dumais-Huber, C., Zerfass, R., Henn, F. A., Aldenhoff, J. B. (March 1999) The calcium response of human T lymphocytes is decreased in aging but increased in Alzheimer's dementia. Biological Psychiatry, 45 (6). pp. 737-42. ISSN 0006-3223 (Print)0006-3223 (Linking)
Sun, H., Charles, C. H., Lau, L. F., Tonks, N. K. (November 1993) MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell, 75 (3). pp. 487-493. ISSN 0092-8674
Sun, H., Tonks, N. K. (November 1994) The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends in Biochemical Sciences, 19 (11). pp. 480-485. ISSN 0968-0004
Sun, H., Tonks, N. K., Barsagi, D. (October 1994) Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science, 266 (5183). pp. 285-288. ISSN 0036-8075
Sun, J., Evrin, C., Samel, S. A., Fernandez-Cid, A., Riera, A., Kawakami, H., Stillman, B., Speck, C., Li, H. (August 2013) Cryo-EM structure of a helicase loading intermediate containing ORC-Cdc6-Cdt1-MCM2-7 bound to DNA. Nature Structural and Molecular Biology, 20 (8). pp. 944-951. ISSN 15459993
Sun, Xueqin, Klingbeil, Olaf, Lu, Bin, Wu, Caizhi, Ballon, Carlos, Ouyang, Meng, Wu, Xiaoli S, Jin, Ying, Hwangbo, Yon, Huang, Yu-Han, Somerville, Tim DD, Chang, Kenneth, Park, Jung, Chung, Taemoon, Lyons, Scott K, Shi, Junwei, Vogel, Hannes, Schulder, Michael, Vakoc, Christopher R, Mills, Alea A (December 2022) BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network. Nature. ISSN 0028-0836
Svoboda, K., Mitra, P. P., Block, S. M. (April 1995) Fluctuation analysis of kinesin movement. Biophys J, 68 (4 Supp). 69S. ISSN 0006-3495 (Print)
Svoboda, K., Mitra, P. P., Block, S. M. (December 1994) Fluctuation analysis of motor protein movement and single enzyme kinetics. Proc Natl Acad Sci U S A, 91 (25). pp. 11782-6. ISSN 0027-8424
Swedlow, J. R., Hirano, T. (March 2003) The making of the mitotic chromosome: Modern insights into classical questions. Molecular Cell, 11 (3). pp. 557-569. ISSN 1097-2765
T
Tabet, F., Schiffrin, E. L., Callera, G., He, Y., Yao, G., Ostman, A., Kappert, K., Tonks, N. K., Touyz, R. M. (July 2008) Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR. Circ Res, 103 (2). pp. 149-158.
Tansey, W. P., Ejkova, E., Kim, S. Y., Herbst, A., Muratani, M., Salghetti, S. E., Tworkowski, K. A. (March 2003) Transcriptional control and the ubiquitin-proteasome system. Faseb Journal, 17 (5). A1184-A1184 Part 2 Supp. S. ISSN 0892-6638
Teitelman, G., Alpert, S., Hanahan, D. (January 1988) Proliferation, Senescence, and Neoplastic Progression of Beta-Cells in Hyperplasic Pancreatic-Islets. Cell, 52 (1). pp. 97-105. ISSN 0092-8674
Teta, M., Andl, T., Okegbe, T., Murchison, E. P., Nagy, A., Hannon, G. J., Millar, S. E. (April 2008) Global changes in mRNA levels and failure of hair follicle stem cell maintenance in adult Dicer-deleted skin. Journal of Investigative Dermatology, 128 (Suppl.). S154-S154. ISSN 0022-202X
Teta, M., Thomas, A., Okegbe, T., Murchison, E. P., Nagy, A., Hannon, G. J., Millar, S. E. (July 2008) Dicer is required for maintenance of hair follicle stem cells in adult skin. Developmental Biology, 319 (2). p. 556. ISSN 0012-1606
Tian, Congcong, Zhang, Qin, Jia, Jing, Zhou, Jiaqi, Zhang, Ziwei, Karri, Srinivasu, Jiang, Jiuhang, Dickinson, Quinn, Yao, Yuan, Tang, Xiaorong, Huang, Yuxin, Guo, Ting, He, Ziwei, Liu, Zheng, Gao, Yuan, Yang, Xinran, Wu, Yuchun, Chan, Kui Ming, Zhang, Daoqin, Han, Junhong, Yu, Chuanhe, Gan, Haiyun (May 2024) DNA polymerase delta governs parental histone transfer to DNA replication lagging strand. Proceedings of the National Academy of Sciences of the United States of America, 121 (20). e2400610121. ISSN 0027-8424 (Public Dataset)
Tian, C., Ohlund, D., Rickelt, S., Lidstrom, T., Huang, Y., Hao, L., Zhao, R. T., Franklin, O., Bhatia, S. N., Tuveson, D. A., Hynes, R. O. (February 2020) Cancer-cell-derived matrisome proteins promote metastasis in pancreatic ductal adenocarcinoma. Cancer Res, 80 (7). pp. 1461-1474. ISSN 0008-5472
Tiganis, T., Flint, A. J., Adam, S. A., Tonks, N. K. (August 1997) Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97. Journal of Biological Chemistry, 272 (34). pp. 21548-21557. ISSN 0021-9258
Tiganis, T., Kemp, B. E., Tonks, N. K. (September 1999) The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling. Journal of Biological Chemistry, 274 (39). pp. 27768-27775. ISSN 0021-9258
Tonks, Nicholas K (April 2023) Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow. IUBMB Life, 75 (4). pp. 337-352. ISSN 1521-6543
Tonks, N. (November 2012) HARNESSING REDOX REGULATION OF PROTEIN TYROSINE PHOSPHATASES. Free Radical Biology and Medicine, 53 (Supple). S3-S3. ISSN 0891-5849
Tonks, N., Krishnan, N. (2008) Regulation of Protein Tyrsoine Phosphatase by Hydrogen Sulphide. Free Radical Biology and Medicine, 45 (Suppl.). S18-S19. ISSN 0891-5849
Tonks, N., Krishnan, N. (2008) Unraveling the Mechanism of Redox Regulation in Protein Tyrosine Phosphatases. Free Radical Biology and Medicine, 45 (Suppl.). S62-S62. ISSN 0891-5849
Tonks, N. K. (March 2000) From structure to function of protein tyrosine phosphatases. Abstracts of Papers of the American Chemical Society, 219. U7-U7. ISSN 0065-7727
Tonks, N. K. (1998) From structure to function of protein tyrosine phosphatases. Naunyn-Schmiedebergs Archives of Pharmacology, 358 (1). R377-R377. ISSN 0028-1298
Tonks, N. K. (July 1997) From structure to function of protein tyrosine phosphatases. Faseb Journal, 11 (9). A1012-A1012. ISSN 0892-6638
Tonks, N. K. (July 2003) PTP1B: From the sidelines to the front lines! Febs Letters, 546 (1). pp. 140-148. ISSN 0014-5793
Tonks, N. K. (April 2013) Protein Tyrosine Phosphatases: Critical Regulators of Signaling in Cancer. Faseb Journal, 27 (1). ISSN 0892-6638
Tonks, N. K. (January 2013) Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction. Febs Journal, 280 (2). pp. 346-378. ISSN 1742464X
Tonks, N. K. (April 1996) Protein tyrosine phosphatases and the control of the cellular signalling responses. Faseb Journal, 10 (6). P13-P13. ISSN 0892-6638
Tonks, N. K. (April 1994) Protein tyrosine phosphatases and the control of the cellular signalling responses. Faseb Journal, 8 (7). A1377-A1377. ISSN 0892-6638
Tonks, N. K. (November 2006) Protein tyrosine phosphatases: from genes, to function, to disease. Nat Rev Mol Cell Biol, 7 (11). pp. 833-46. ISSN 1471-0072 (Print)
Tonks, N. K. (October 2009) Pseudophosphatases: grab and hold on. Cell, 139 (3). pp. 464-5.
Tonks, N. K., Diltz, C. D., Fischer, E. H. (1991) Purification and assay of CD45: an integral membrane protein-tyrosine phosphatase. Methods in Enzymology, 201. pp. 442-451. ISSN 0076-6879
Tonks, N. K., Diltz, C. D., Fischer, E. H. (1991) Purification of protein-tyrosine phosphatases from human placenta. Methods in Enzymology, 201. pp. 427-442. ISSN 0076-6879
Tonks, N. K., Muthuswamy, S. K. (March 2007) A Brake Becomes an Accelerator: PTP1B-A New Therapeutic Target for Breast Cancer. Cancer Cell, 11 (3). pp. 214-6. ISSN 1535-6108 (Print)
Tonks, N. K., Myers, M. P. (December 1999) Structural assets of a tumor suppressor. Science, 286 (5447). pp. 2096-2097. ISSN 0036-8075
Tonks, N. K., Neel, B. G. (April 2001) Combinatorial control of the specificity of protein tyrosine phosphatases. Current Opinion in Cell Biology, 13 (2). pp. 182-195. ISSN 0955-0674
Tonks, N. K., Neel, B. G. (November 1996) From form to function: Signaling by protein tyrosine phosphatases. Cell, 87 (3). pp. 365-368. ISSN 0092-8674
Tonks, N. K., Yang, Q., Flint, A. J., Gebbink, M. F., Franza, B. R., Hill, D. E., Sun, H., Brady-Kalnay, S. M. (1992) Protein tyrosine phosphatases: the problems of a growing family. Cold Spring Harbor Symposia on Quantitative Biology, 57. pp. 87-94. ISSN 0091-7451
Tonks, N. K., Yang, Q., Guida, P. (1991) Structure, regulation, and function of protein tyrosine phosphatases. Cold Spring Harbor Symposia on Quantitative Biology, 56. pp. 265-273. ISSN 0091-7451
Tonks, N. K. (November 2012) Talk from Nick Tonks at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)
Torres, J., Rodriguez, J., Myers, M. P., Valiente, M., Graves, J. D., Tonks, N. K., Pulido, R. (August 2003) Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3 - Implications for the control of protein stability and PTEN-protein interactions. Journal of Biological Chemistry, 278 (33). pp. 30652-30660. ISSN 0021-9258
Trotman, L. C. (2010) PTEN. In: Handbook of Cell Signaling (Second Edition). Academic Press, San Diego, pp. 849-854. ISBN 978-0-12-374145-5
Tsai, Y. H., Van Dussen, K. L., Sawey, E. T., Wade, A. W., Kasper, C., Rakshit, S., Bhatt, R. G., Stoeck, A., Maillard, I., Crawford, H. C., Samuelson, L. C., Dempsey, P. J. (July 2014) ADAM10 Regulates Notch Function in Intestinal Stem Cells of Mice. Gastroenterology. ISSN 0016-5085
Tummala, M., Ryzhov, V., Ravi, K., Black, S. M., Ravi, K. (January 2008) Identification of the cysteine nitrosylation sites in human endothelial nitric oxide synthase. DNA and Cell Biology, 27 (1). pp. 25-33. ISSN 1044-5498
V
Varshavsky, A., Turner, G., Du, F., Xie, Y. (2000) The ubiquitin system and the N-end rule pathway. Biological Chemistry, 381 (9-10). pp. 779-789. ISSN 14316730 (ISSN)
Vi, S. L., Trost, G., Lange, P., Czesnick, H., Rao, N., Lieber, D., Laux, T., Gray, W. M., Manley, J. L., Groth, D., Kappel, C., Lenhard, M. (August 2013) Target specificity among canonical nuclear poly(A) polymerases in plants modulates organ growth and pathogen response. Proceedings of the National Academy of Sciences of the United States of America, 110 (34). pp. 13994-13999. ISSN 00278424
W
Waga, S., Hannon, G. J., Beach, D., Stillman, B. (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature, 369 (6481). pp. 574-578. ISSN 00280836 (ISSN)
Wang, D. G., Fan, J. B., Siao, C. J., Berno, A., Young, P., Sapolsky, R., Ghandour, G., Perkins, N., Winchester, E., Spencer, J., Kruglyak, L., Stein, L., Hsie, L., Topaloglou, T., Hubbell, E., Robinson, E., Mittmann, M., Morris, M. S., Shen, N. P., Kilburn, D., Rioux, J., Nusbaum, C., Rozen, S., Hudson, T. J., Lipshutz, R., Chee, M., Lander, E. S. (May 1998) Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. Science, 280 (5366). pp. 1077-1082. ISSN 0036-8075
Wang, E., Kawaoka, S., Yu, M., Shi, J., Ni, T., Yang, W., Zhu, J., Roeder, R. G., Vakoc, C. R. (March 2013) Histone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemia. Proceedings of the National Academy of Sciences of the United States of America, 110 (10). pp. 3901-6. ISSN 1091-6490 (Electronic)0027-8424 (Linking)
Wang, J., Hannon, G. J., Beach, D. H. (2000) Risky immortalization by telomerase. Nature, 405 (6788). pp. 755-756. ISSN 00280836 (ISSN)
Wang, J., Xie, L. Y., Allan, S., Beach, D., Hannon, G. J. (1998) Myc activates telomerase. Genes and Development, 12 (12). pp. 1769-1774. ISSN 08909369 (ISSN)
Wang, Zhenxing, Butel, Nicolas, Santos-González, Juan, Borges, Filipe, Yi, Jun, Martienssen, Robert A, Martinez, German, Köhler, Claudia (April 2020) Polymerase IV Plays a Crucial Role in Pollen Development in Capsella. The Plant Cell, 32 (4). pp. 950-966. ISSN 1040-4651
Wen, Qing, Zhou, Jiaqi, Tian, Congcong, Li, Xinran, Song, Guibing, Gao, Yuan, Sun, Yaping, Ma, Chiyuan, Yao, Sitong, Liang, Xiaoyan, Kang, Xing, Wang, Nan, Yao, Yuan, Wang, Hongbao, Liang, Xiaohuan, Tang, Jialin, Offer, Steven M, Lei, Xiaohua, Yu, Chuanhe, Liu, Xiangyu, Liu, Zichuan, Wang, Zhiquan, Gan, Haiyun (September 2023) Symmetric inheritance of parental histones contributes to safeguarding the fate of mouse embryonic stem cells during differentiation. Nature Genetics, 55 (9). pp. 1555-1566. ISSN 1061-4036
Wigler, M. H., Ford, J. P., Weinstein, I. B. (1975) Glucocorticoid inhibition of the fibrinolytic activity of tumor cells. In: Proteases and Biological Control. Cold Spring Harbor Conferences on Cell Proliferation, 2 . Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, 849−856 . ISBN 0097-5230
Wysocka, J., Myers, M. P., Laherty, C. D., Eisenman, R. N., Herr, W. (April 2003) Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1. Genes and Development, 17 (7). pp. 896-911. ISSN 08909369 (ISSN)
X
Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., Beach, D. (1993) p21 is a universal inhibitor of cyclin kinases. Nature, 366 (6456). pp. 701-704. ISSN 00280836 (ISSN)
Xu, M. Z., Chan, S. W., Liu, A. M., Wong, K. F., Fan, S. T., Chen, J., Poon, R. T., Zender, L., Lowe, S. W., Hong, W., Luk, J. M. (March 2011) AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma. Oncogene, 30 (10). pp. 1229-1240.
Y
Yang, Q., Co, D., Sommercorn, J., Tonks, N. K. (March 1993) Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase. Journal of Biological Chemistry, 268 (9). pp. 6622-6628. ISSN 0021-9258
Yang, Q., Tonks, N. K. (July 1991) Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin. Proceedings of the National Academy of Sciences of the United States of America, 88 (14). pp. 5949-5953. ISSN 0027-8424
Yang, Yang, Paul, Anirban, Bach, Thao Nguyen, Huang, Z Josh, Zhang, Michael Q (July 2021) Single-cell alternative polyadenylation analysis delineates GABAergic neuron types. BMC Biology, 19 (1). p. 144. ISSN 1741-7007
Yao, Min, Preall, Jonathan, Yeh, Johannes, Pappin, Darryl J, Cifani, Paolo, Zhao, Yixin, Shen, Sophia, Moresco, Philip, He, Brian, Patel, Hardik, Habowski, Amber N, King, Daniel A, Raphael, Kara L, Rishi, Arvind, Sejpal, Divyesh V, Weiss, Matthew, Tuveson, David, Fearon, Douglas T (September 2023) Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens. JCI Insight. e172449. ISSN 2379-3708 (Public Dataset)
Yao, Z., Fenoglio, S., Gao, D. C., Camiolo, M., Stiles, B., Lindsted, T., Schlederer, M., Johns, C., Altorki, N., Mittal, V., Kenner, L., Sordella, R. (August 2010) TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proceedings of the National Academy of Sciences of the United States of America, 107 (35). pp. 15535-40. ISSN 0027-8424
Yart, A., Laffargue, M., Mayeux, P., Chretien, S., Peres, C., Tonks, N., Roche, S., Payrastre, B., Chap, H., Raynal, P. (March 2001) A critical pole for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of Ras and mitogen-activated protein kinases by epidermal growth factor. Journal of Biological Chemistry, 276 (12). pp. 8856-8864. ISSN 0021-9258
Yoshimi, A., Lin, K. T., Wiseman, D. H., Rahman, M. A., Pastore, A., Wang, B., Lee, S. C., Micol, J. B., Zhang, X. J., de Botton, S., Penard-Lacronique, V., Stein, E. M., Cho, H., Miles, R. E., Inoue, D., Albrecht, T. R., Somervaille, T. C. P., Batta, K., Amaral, F., Simeoni, F., Wilks, D. P., Cargo, C., Intlekofer, A. M., Levine, R. L., Dvinge, H., Bradley, R. K., Wagner, E. J., Krainer, A. R., Abdel-Wahab, O. (October 2019) Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis. Nature, 574 (7777). pp. 273-277. ISSN 0028-0836
Young, D., O'Neill, K., Broek, D., Wigler, M. H. (June 1991) The adenylyl cyclase-encoding gene from Saccharomyces kluyveri. Gene, 102 (1). pp. 129-32. ISSN 0378-1119
Young, D., Riggs, M., Field, J., Vojtek, A., Broek, D., Wigler, M. H. (October 1989) The adenylyl cyclase gene from Schizosaccharomyces pombe. Proc Natl Acad Sci U S A, 86 (20). pp. 7989-93. ISSN 0027-8424
Z
Zander, N. F., Lorenzen, J. A., Cool, D. E., Tonks, N. K., Daum, G., Krebs, E. G., Fischer, E. H. (July 1991) Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system. Biochemistry, 30 (28). pp. 6964-6970. ISSN 0006-2960
Zhang, H., Hannon, G. J., Beach, D. (1994) p21-Containing cyclin kinases exist in both active and inactive states. Genes and Development, 8 (15). pp. 1750-1758. ISSN 08909369 (ISSN)
Zhang, H., Hannon, G. J., Casso, D., Beach, D. (1994) p21 is a component of active cell cycle kinases. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 21-29. ISSN 00917451 (ISSN)
Zhang, S. H., Eckberg, W. R., Yang, Q., Samatar, A. A., Tonks, N. K. (August 1995) Biochemical characterization of a human band 4.1-related protein-tyrosine phosphatase, PTPH1. Journal of Biological Chemistry, 270 (34). pp. 20067-20072. ISSN 0021-9258
Zhang, S. H., Kobayashi, R., Graves, P. R., Piwnica-Worms, H., Tonks, N. K. (October 1997) Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3 beta protein. Journal of Biological Chemistry, 272 (43). pp. 27281-27287. ISSN 0021-9258
Zhang, S. H., Liu, J. P., Kobayashi, R., Tonks, N. K. (June 1999) Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1. Journal of Biological Chemistry, 274 (25). pp. 17806-17812. ISSN 0021-9258
Zhang, S. H., Tonks, N. K. (December 1996) Phosphorylation-dependent association of band 4.1-related protein tyrosine phosphatase PTPH1 and 14-3-3B. Molecular Biology of the Cell, 7. p. 83. ISSN 1059-1524
Zhang, Qian, Yang, Lucia, Liu, Ying Hsiu, Wilkinson, John E, Krainer, Adrian R (April 2023) Antisense oligonucleotide therapy for H3.3K27M diffuse midline glioma. Science Translational Medicine, 15 (691). eadd8280. ISSN 1946-6234
Zhao, Yixin, Liu, Lingjie, Hassett, Rebecca, Siepel, Adam (October 2023) Model-based characterization of the equilibrium dynamics of transcription initiation and promoter-proximal pausing in human cells. Nucleic Acids Research. ISSN 0305-1048
Zhao, M. M., Schmitz, A. A. P., Qin, Y., Di Cristofano, A., Pandolfi, P. P., Van Aelst, L. (August 2001) Phosphoinositide 3-kinase-dependent membrane recruitment of p62(dok) is essential for its negative effect on mitogen-activated protein (MAP) kinase activation. Journal of Experimental Medicine, 194 (3). pp. 265-274. ISSN 0022-1007
Zhao, X. M., Schramm, L., Hernandez, N., Herr, W. (January 2003) A shared surface of TBP directs RNA polymerase II and III transcription via association with different TFIIB family members. Molecular Cell, 11 (1). pp. 151-161. ISSN 1097-2765
Zheng, J. Y., Yang, X. M., Harrell, J. M., Ryzhikov, S., Shim, E. H., Lykke-Andersen, K., Wei, N., Sun, H., Kobayashi, R., Zhang, H. (December 2002) CAND1 binds to unneddylated CUL1 and regulates the formation of SCF ubiquitin E3 ligase complex. Molecular Cell, 10 (6). pp. 1519-1526. ISSN 1097-2765
Zheng, Q., Woehl, J. L., Kitamura, S., Santos-Martins, D., Smedley, C. J., Li, G., Forli, S., Moses, J. E., Wolan, D. W., Sharpless, K. B. (September 2019) SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proc Natl Acad Sci U S A, 116 (38). pp. 18808-18814. ISSN 0027-8424 (Print)0027-8424
Zhong, H., Sia, G.-M., Sato, T. R., Gray, N. W., Mao, T., Khuchua, Z., Huganir, R. L., Svoboda, K. (May 2009) Subcellular Dynamics of Type II PKA in Neurons. Neuron, 62 (3). pp. 363-374.
Zhou, J. L., Hidaka, K., Futcher, B. (March 2000) The Est1 subunit of yeast telomerase binds the Tlc1 telomerase RNA. Molecular and Cellular Biology, 20 (6). pp. 1947-1955. ISSN 0270-7306
Zipser, B. (1980) Horseradish-Peroxidase Nerve Backfilling in Leech. Brain Research, 182 (2). pp. 441-445.
Zuo, Y., Yalavarthi, S., Shi, H., Gockman, K., Zuo, M., Madison, J.A., Blair, C.N., Weber, A., Barnes, B.J., Egeblad, M., Woods, R.J., Kanthi, Y., Knight, J.S. (June 2020) Neutrophil Extracellular Traps in COVID-19. JCI Insight, 5 (11). p. 138999. ISSN 2379-3708