Items where Subject is "bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > enzymes > protein tyrosine phosphatase"

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Number of items at this level: 145.

A

Andersen, J. N., Jansen, P. G., Echwald, S. M., Mortensen, O. H., Fukada, T., Del Vecchio, R., Tonks, N. K., Moller, N. P. (2004) A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage. FASEB J, 18 (1). pp. 8-30. ISSN 1530-6860 (Electronic)

Andersen, J. N., Mortensen, O. H., Peters, G. H., Drake, P. G., Iversen, L. F., Olsen, O. H., Jansen, P. G., Andersen, H. S., Tonks, N. K., Moller, N. P. H. (2001) Structural and evolutionary relationships among protein tyrosine phosphatase domains. Molecular and Cellular Biology, 21 (21). pp. 7117-7136. ISSN 0270-7306

Andersen, J. N., Tonks, N. K. (2004) Protein tyrosine phosphatase-based therapeutics- lessons from PTP1B. In: Protein phosphatases. Topics in current genetics, 5 . Springer-Verlag, Berlin, pp. 201-230. ISBN 3540205608

B

Baratte, B., Meijer, L., Galaktionov, K., Beach, D. (1992) Screening for antimitotic compounds using the cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2/cyclin Bcdc13 protein kinase. Anticancer Research, 12 (3). pp. 873-880. ISSN 0250-7005

Barford, D., Flint, A. J., Tonks, N. K. (1994) Crystal structure of human protein tyrosine phosphatase 1B. Science, 263 (5152). pp. 1397-1404.

Barford, D., Jia, Z. C., Tonks, N. K. (1995) Protein tyrosine phosphatases take off. Nature Structural Biology, 2 (12). pp. 1043-1053. ISSN 1072-8368

Barford, D., Keller, J. C., Flint, A. J., Tonks, N. K. (1994) Purification and crystallization of the catalytic domain of human protein tyrosine phosphatase 1B expressed in Escherichia coli. Journal of Molecular Biology, 239 (5). pp. 726-730. ISSN 0022-2836

Bartlet-Jones, M., Jeffery, W. A., Hansen, H. F., Pappin, D. J. C. (1995) The use of a volatile N-terminal degradation reagent for rapid, high-sensitivity sequence analysis of peptides by generation of sequence ladders. In: Techniques in Protein Chemistry. Academic Press, pp. 3-11. ISBN 1080-8914

Barton, G. J., Cohen, P. T. W., Barford, D. (1994) Conservation Analysis and Structure Prediction of the Protein Serine/Threonine Phosphatases - Sequence Similarity with Diadenosine Tetraphosphatase from Escherichia-Coli Suggests Homology to the Protein Phosphatases. European Journal of Biochemistry, 220 (1). pp. 225-237. ISSN 0014-2956

Bianchi, C., Sellke, F. W., Del Vecchio, R. L., Tonks, N. K., Neel, B. G. (1999) Receptor-type protein-tyrosine phosphatase mu is expressed in specific vascular endothelial beds in vivo. Experimental Cell Research, 248 (1). pp. 329-338. ISSN 0014-4827

Boivin, B., Chaudhary, F., Dickinson, B. C., Haque, A., Pero, S. C., Chang, C. J., Tonks, N. K. (2013) Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein mediated mammary epithelial cell motility. Journal of Biological Chemistry, 288 (52). pp. 36926-36935. ISSN 00219258 (ISSN)

Boivin, B., Tonks, N. K. (2010) Analysis of the redox regulation of protein tyrosine phosphatase superfamily members utilizing a cysteinyl-labeling assay. In: Thiol Redox Transitions in Cell Signaling, Part B: Cellular Localization and Signaling. Methods in Enzymology, 474 . Elsevier Academic Press Inc, San Diego, pp. 35-50. ISBN 0076-6879978-0-12-381003-8

Boivin, B., Zhang, S. H., Arbiser, J. L., Zhang, Z.-Y., Tonks, N. K. (2008) A modified cysteinyl-labeling assay reveals reversible oxidation of classical and dual specificity phosphatases in angiomyolipoma cells. Proc Natl Acad Sci U S A, 105 (29). pp. 9959-9964.

Brady-Kalnay, S. M., Flint, A. J., Tonks, N. K. (1993) Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation. Journal of Cell Biology, 122 (4). pp. 961-972. ISSN 0021-9525

Brady-Kalnay, S. M., Mourton, T., Nixon, J. P., Pietz, G. E., Kinch, M., Chen, H. Y., Brackenbury, R., Rimm, D. L., Del Vecchio, R. L., Tonks, N. K. (1998) Dynamic interaction of PTP mu with multiple cadherins in vivo. Journal of Cell Biology, 141 (1). pp. 287-296. ISSN 0021-9525

Brady-Kalnay, S. M., Rimm, D. L., Tonks, N. K. (1995) Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo. Journal of Cell Biology, 130 (4). pp. 977-986. ISSN 0021-9525

Brady-Kalnay, S. M., Rimm, D. L., Tonks, N. K. (1995) The receptor protein-tyrosine-phosphatase PTP-mu associates with cadherins and catenins. Molecular Biology of the Cell, 6. p. 676. ISSN 1059-1524

Brady-Kalnay, S. M., Tonks, N. K. (1994) Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu. Journal of Biological Chemistry, 269 (45). pp. 28472-28477. ISSN 0021-9258

Brady-Kalnay, S. M., Tonks, N. K. (1995) Protein tyrosine phosphatases as adhesion receptors. Current Opinion in Cell Biology, 7 (5). pp. 650-657. ISSN 0955-0674

Brady-Kalnay, S. M., Tonks, N. K. (1994) Protein tyrosine phosphatases: from structure to function. Trends Cell Biol, 4 (3). pp. 73-6. ISSN 0962-8924 (Print)

Brady-Kalnay, S. M., Tonks, N. K. (1993) Purification and characterization of the human protein tyrosine phosphatase, PTP mu, from a baculovirus expression system. Molecular and Cellular Biochemistry, 128. pp. 131-141. ISSN 0300-8177

Bukczynska, P., Klingler-Hoffmann, M., Mitchelhill, K. I., Lam, M. H. C., Ciccomancini, M., Tonks, N. K., Sarcevic, B., Kemp, B. E., Tiganis, T. (2004) The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis. Biochemical Journal, 380. pp. 939-949. ISSN 0264-6021

C

Charbonneau, H., Tonks, N. K. (1992) 1002 Protein Phosphatases? Annual Review of Cell Biology, 8. pp. 463-493. ISSN 0743-4634

Charles, C. H., Sun, H., Lau, L. F., Tonks, N. K. (1993) The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 90 (11). pp. 5292-5296. ISSN 0027-8424

Chaudhary, F., Lucito, R., Tonks, N. K. (2014) Missing-in-Metastasis regulates cell motility and invasion via PTPdelta-mediated changes in SRC activity. Biochemical Journal, 465 (1). pp. 89-101. ISSN 0264-6021

Chen, H. H., Luche, R., Wei, B., Tonks, N. K. (2004) Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2. J Biol Chem, 279 (40). pp. 41404-13. ISSN 0021-9258 (Print)

Cool, D. E., Andreassen, P. R., Tonks, N. K., Krebs, E. G., Fischer, E. H., Margolis, R. L. (1992) Cytokinetic failure and asynchronous nuclear division in BHK cells overexpressing a truncated protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 89 (12). pp. 5422-5426. ISSN 0027-8424

D

Dagnell, M., Frijhoff, J., Pader, I., Augsten, M., Boivin, B., Xu, J., Mandal, P. K., Tonks, N. K., Hellberg, C., Conrad, M., Arnér, E. S. J., Östman, A. (2013) Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-ß receptor tyrosine kinase signaling. Proceedings of the National Academy of Sciences of the United States of America, 110 (33). pp. 13398-13403. ISSN 00278424

Del Vecchio, R. L., Tonks, N. K. (2005) The conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase mu. J Biol Chem, 280 (2). pp. 1603-12. ISSN 0021-9258 (Print)

Delvecchio, R. L., Tonks, N. K. (1994) Characterization of two structurally related Xenopus laevis protein tyrosine phosphatases with homology to lipid-binding proteins. Journal of Biological Chemistry, 269 (30). pp. 19639-19645. ISSN 0021-9258

Demetrick, D. J., Beach, D. H. (1993) Chromosome mapping of human CDC25A and CDC25B phosphatases. Genomics, 18 (1). pp. 144-7. ISSN 0888-7543 (Print)

F

Fan, G., Aleem, S., Yang, M., Miller, W. T., Tonks, N. K. (2015) Protein Tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and BRK. Journal of Biological Chemistry, 290 (26). pp. 15934-15947. ISSN 0021-9258

Fan, G., Lin, G., Lucito, R., Tonks, N. K. (2013) Protein Tyrosine Phosphatase 1B Antagonized Signaling by IGF-1 Receptor and BRK/PTK6 in Ovarian Cancer Cells. Journal of Biological Chemistry, 288 (34). pp. 24923-29434. ISSN 0021-9258

Fischer, E. H., Charbonneau, H., Cool, D. E., Tonks, N. K. (1992) Tyrosine phosphatases and their possible interplay with tyrosine kinases. Ciba Foundation Symposia, 164. pp. 132-144. ISSN 0300-5208

Flint, A. J., Gebbink, M. F., Franza, B. R., Hill, D. E., Tonks, N. K. (1993) Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation. Embo Journal, 12 (5). pp. 1937-1946. ISSN 0261-4189

Flint, A. J., Tiganis, T., Barford, D., Tonks, N. K. (1997) Development of ''substrate-trapping'' mutants to identify physiological substrates of protein tyrosine phosphatases. Proceedings of the National Academy of Sciences of the United States of America, 94 (5). pp. 1680-1685. ISSN 0027-8424

Fukada, T., Tonks, N. K. (2003) Identification of YB-1 as a regulator of PTP1B expression: implications for regulation of insulin and cytokine signaling. Embo Journal, 22 (3). pp. 479-493. ISSN 0261-4189

Fukada, T., Tonks, N. K. (2001) The reciprocal role of Egr-1 and Sp family proteins in regulation of the PTP1B promoter in response to the p210 Bcr-Abl oncoprotein-tyrosine kinase. Journal of Biological Chemistry, 276 (27). pp. 25512-25519. ISSN 0021-9258

G

Galaktionov, K., Beach, D. (1991) Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. Cell, 67 (6). pp. 1181-94. ISSN 0092-8674 (Print)0092-8674 (Linking)

Galic, S., Hauser, C., Kahn, B. B., Haj, F. G., Neel, B. G., Tonks, N. K., Tiganis, T. (2005) Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP. Molecular and Cellular Biology, 25 (2). pp. 819-829. ISSN 0270-7306

Galic, S., Klingler-Hoffmann, M., Fodero-Tavoletti, M. T., Puryer, M. A., Meng, T. C., Tonks, N. K., Tiganis, T. (2003) Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP. Molecular and Cellular Biology, 23 (6). pp. 2096-2108. ISSN 0270-7306

Garton, A. J., Burnham, M. R., Bouton, A. H., Tonks, N. K. (1997) Association of PTP-PEST with the SH3 domain of p130(cas); a novel mechanism of protein tyrosine phosphatase substrate recognition. Oncogene, 15 (8). pp. 877-885. ISSN 0950-9232

Garton, A. J., Flint, A. J., Tonks, N. K. (1996) Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST. Molecular and Cellular Biology, 16 (11). pp. 6408-6418. ISSN 0270-7306

Garton, A. J., Tonks, N. K. (1994) PTP-PEST: a protein tyrosine phosphatase regulated by serine phosphorylation. Embo Journal, 13 (16). pp. 3763-3771. ISSN 0261-4189

Garton, A. J., Tonks, N. K. (1999) Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST. Journal of Biological Chemistry, 274 (6). pp. 3811-3818. ISSN 0021-9258

Gutch, M. J., Flint, A. J., Keller, J., Tonks, N. K., Hengartner, M. O. (1998) The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development. Genes & Development, 12 (4). pp. 571-585. ISSN 0890-9369

H

Hao, L. N., Tiganis, T., Tonks, N. K., Charbonneau, H. (1997) The noncatalytic C-terminal segment of the T cell protein tyrosine phosphatase regulates activity via an intramolecular mechanism. Journal of Biological Chemistry, 272 (46). pp. 29322-29329. ISSN 0021-9258

Harrington, R. J., Gutch, M. J., Hengartner, M. O., Tonks, N. K., Chisholm, A. D. (2002) The C-elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis. Development, 129 (9). pp. 2141-2153. ISSN 0950-1991

Hinton, S. D., Yang, D. Z., Eckberg, W. R. (2003) Protein tyrosine phosphatases in Chaetopterus egg activation. Development Growth & Differentiation, 45 (5-6). pp. 405-415. ISSN 0012-1592

Hoffmann, K. M. V., Tonks, N. K., Barford, D. (1997) The crystal structure of domain 1 of receptor protein-tyrosine phosphatase mu. Journal of Biological Chemistry, 272 (44). pp. 27505-27508. ISSN 0021-9258

Hyun, S. W., Sui, X., Del Vecchio, R. L., Tonks, N. K., Passaniti, A., Goldblum, S. E. (2004) Protein tyrosine phosphatase (PTP) mu regulates endothelial cell (EC) proliferation, adhesion and migration. Molecular Biology of the Cell, 15. 226A-226A. ISSN 1059-1524

J

Jia, Z. C., Barford, D., Flint, A. J., Tonks, N. K. (1995) Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268 (5218). pp. 1754-1758. ISSN 0036-8075

K

Kontaridis, M. I., Eminaga, S., Fornaro, M., Zito, C. I., Sordella, R., Settleman, J., Bennett, A. M. (2004) SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Molecular and Cellular Biology, 24 (12). pp. 5340-52. ISSN 0270-7306

Krishnan, N. (2012) Regulation of Protein Tyrsoine Phosphatase by Hydrogen Sulfide. Free Radical Biology and Medicine, 53 (Supple). S33-S33. ISSN 0891-5849

Krishnan, N., Bencze, G., Cohen, P., Tonks, N. K. (2013) The anti-inflammatory compound BAY 11-7082 is a potent inhibitor of Protein Tyrosine Phosphatases. FEBS Journal, 280 (12). pp. 2830-2841. ISSN 1742-464X

Krishnan, N., Fu, C., Pappin, D. J., Tonks, N. K. (2011) H2S-induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response. Science Signaling, 4 (203). ISSN 19450877 (ISSN)

Krishnan, N., Konidaris, K. F., Gasser, G., Tonks, N. K. (2017) A potent, selective and orally bioavailable inhibitor of the protein tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models. J Biol Chem. ISSN 0021-9258

Krishnan, N., Koveal, D., Miller, D. H., Xue, B., Akshinthala, S. D., Kragelj, J., Jensen, M. R., Gauss, C. M., Page, R., Blackledge, M., Muthuswamy, S. K., Peti, W., Tonks, N. K. (2014) Targeting the disordered C terminus of PTP1B with an allosteric inhibitor. Nature Chemical Biology, 10 (7). pp. 558-566. ISSN 15524450

Krishnan, N., Krishnan, K., Connors, C. R., Choy, M. S., Page, R., Peti, W., Van Aelst, L., Shea, S. D., Tonks, N. K. (2015) PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest, 125 (8). pp. 3163-3177. ISSN 1558-8238 (Electronic)0021-9738 (Linking)

Krishnan, Navasona, Tonks, Nicholas K. (2015) Anxious moments for the protein tyrosine phosphatase PTP1B. Trends in Neurosciences, 38 (8). pp. 462-465. ISSN 0166-2236

L

La Montagne, K. R., Flint, A. J., Franza, B. R., Pendergast, A. M., Tonks, N. K. (1998) Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo. Molecular and Cellular Biology, 18 (5). pp. 2965-2975. ISSN 0270-7306

La Montagne, K. R., Pendergast, A. M., Franza, B. R., Tonks, N. K. (1995) Enhanced expression of a protein-tyrosine phosphatase in cells expressing P210BCR/ABL. Journal of Cellular Biochemistry. p. 65. ISSN 0730-2312

LaMontagne, K. R., Hannon, G., Tonks, N. K. (1998) Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells. Proceedings of the National Academy of Sciences of the United States of America, 95 (24). pp. 14094-14099. ISSN 0027-8424

Labbe, D. P., Uetani, N., Vinette, V., Lessard, L., Aubry, I., Migon, E., Sirois, J., Haigh, J., Begin, L. R., Trotman, L. C., Paquet, M., Tremblay, M. L. (2016) PTP1B deficiency enables the ability of a high fat diet to drive the invasive character of PTEN-deficient prostate cancers. Cancer Res, 76 (11). pp. 3130-3135. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Lai, C. C., Boguski, M., Broek, D., Powers, S. (1993) Influence of guanine nucleotides on complex formation between Ras and CDC25 proteins. Mol Cell Biol, 13 (3). pp. 1345-52. ISSN 0270-7306 (Print)0270-7306

Lam, M. H. C., Michell, B. J., Fodero-Tavoletti, M. T., Kemp, B. E., Tonks, N. K., Tiganis, T. (2001) Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase TCPTP. Journal of Biological Chemistry, 276 (40). pp. 37700-37707. ISSN 0021-9258

Lammers, R., Bossenmaier, B., Cool, D. E., Tonks, N. K., Schlessinger, J., Fischer, E. H., Ullrich, A. (1993) Differential activities of protein tyrosine phosphatases in intact cells. Journal of Biological Chemistry, 268 (30). pp. 22456-22462. ISSN 0021-9258

Lavoie, C., Chevet, E., Roy, L., Tonks, N. K., Fazel, A., Posner, B. I., Paiement, J., Bergeron, J. J. M. (2000) Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro. Proceedings of the National Academy of Sciences of the United States of America, 97 (25). pp. 13637-13642. ISSN 0027-8424

Li, J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., Parsons, R. (1997) PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 275 (5308). pp. 1943-7. ISSN 0036-8075 (Print)

Lin, G., Aranda, V., Muthuswamy, S. K., Tonks, N. K. (2011) Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'. Genes & Development, 25 (13). pp. 1412-1425. ISSN 0890-9369

Lindtner, C., Scherer, T., Zielinski, E., Filatova, N., Fasshauer, M., Tonks, N. K., Puchowicz, M., Buettner, C. (2013) Binge Drinking Induces Whole-Body Insulin Resistance by Impairing Hypothalamic Insulin Action. Science Translational Medicine, 5 (170). ISSN 1946-6234

Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B. J., Skiba, B., Ooms, L. M., Stepto, N., Wu, B., Mitchell, C. A., Tonks, N. K., Watt, M. J., Febbraio, M. A., Crack, P. J., Andrikopoulos, S., Tiganis, T. (2009) Reactive Oxygen Species Enhance Insulin Sensitivity. Cell Metabolism, 10 (4). pp. 260-272.

Lou, Y.-W., Chen, Y.-Y., Hsu, S.-F., Chen, R.-K., Lee, C.-L., Khoo, K.-H., Tonks, N. K., Meng, T.-C. (2008) Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells. FEBS Journal, 275 (1). pp. 69-88.

M

MacKintosh, C., Garton, A. J., McDonnell, A., Barford, D., Cohen, P. T. W., Tonks, N. K., Cohen, P. (1996) Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation. Febs Letters, 397 (2-3). pp. 235-238. ISSN 0014-5793

McGuire, M. C., Fields, R. M., Nyomba, B. L., Raz, I., Bogardus, C., Tonks, N. K., Sommercorn, J. (1991) Abnormal regulation of protein tyrosine phosphatase activities in skeletal muscle of insulin-resistant humans. Diabetes, 40 (7). pp. 939-942. ISSN 0012-1797

Meng, T. C., Buckley, D. A., Galic, S., Tiganis, T., Tonks, N. K. (2004) Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J Biol Chem, 279 (36). pp. 37716-25. ISSN 0021-9258 (Print)

Meng, T. C., Fukada, T., Tonks, N. K. (2002) Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Molecular Cell, 9 (2). pp. 387-399. ISSN 1097-2765

Meng, T. C., Hsu, S. F., Tonks, N. K. (2005) Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo. Methods, 35 (1). pp. 28-36. ISSN 1046-2023

Meng, T. C., Tonks, N. K. (2003) Analysis of the regulation of protein tyrosine phosphatases in vivo by reversible oxidation. In: Protein Phosphatases. Methods in Enzymology, 366 . Academic Press Inc, San Diego, pp. 304-318. ISBN 0076-6879

Mondol, A. S., Tonks, N. K., Kamata, T. (2014) Nox4 redox regulation of PTP1B contributes to the proliferation and migration of glioblastoma cells by modulating tyrosine phosphorylation of coronin-1C. Free Radical Biology and Medicine, 67. pp. 285-91. ISSN 0891-5849

Moskal, D., Tonks, N. K., Lucito, R. (2015) Alteration of the protein tyrosine phosphatome in cancer. Cancer Research, 75 (Supple). Abstract 1933. ISSN 0008-5472

Myers, M. P., Andersen, J. N., Cheng, A., Tremblay, M. L., Horvath, C. M., Parisien, J. P., Salmeen, A., Barford, D., Tonks, N. K. (2001) TYK2 and JAR2 are substrates of protein-tyrosine phosphatase 1B. Journal of Biological Chemistry, 276 (51). pp. 47771-47774. ISSN 0021-9258

Myers, M. P., Pass, I., Batty, I. H., Van der Kaay, J., Stolarov, J. P., Hemmings, B. A., Wigler, M. H., Downes, C. P., Tonks, N. K. (1998) The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A, 95 (23). pp. 13513-8. ISSN 0027-8424 (Print)

Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., Tonks, N. K. (1997) P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A, 94 (17). pp. 9052-7. ISSN 0027-8424 (Print)

Myers, M. P., Tonks, N. K. (1997) PTEN: Sometimes taking it off can be better than putting it on. American Journal of Human Genetics, 61 (6). pp. 1234-1238. ISSN 0002-9297

N

Neel, B. G., Tonks, N. K. (1997) Protein tyrosine phosphatases in signal transduction. Current Opinion in Cell Biology, 9 (2). pp. 193-204. ISSN 0955-0674

Nelson, K., Meng, T. C., Tonks, N., Melendez, J. A. (2002) Mitochondrial H2O2 enhances matrix metalloproteinase expression by protein tyrosine phosphatase inactivation. Free Radical Biology and Medicine, 33. S355-S355. ISSN 0891-5849

O

Ostman, A., Yang, Q., Tonks, N. K. (1994) Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density. Proceedings of the National Academy of Sciences of the United States of America, 91 (21). pp. 9680-9684. ISSN 0027-8424

P

Palka, H. L., Park, M., Tonks, N. K. (2003) Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1. Journal of Biological Chemistry, 278 (8). pp. 5728-35. ISSN 0021-9258

Pannifer, A. D. B., Flint, A. J., Tonks, N. K., Barford, D. (1998) Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by X-ray crystallography. Journal of Biological Chemistry, 273 (17). pp. 10454-10462. ISSN 0021-9258

Park, C. Y., La Montagne, K. R., Tonks, N. K., Hayman, M. J. (1996) Cloning and expression of the chicken protein tyrosine phosphatase SH-PTP2. Gene, 177 (1-2). pp. 93-97. ISSN 0378-1119

Potts, M., Sun, H., Mockaitis, K., Kennelly, P. J., Reed, D., Tonks, N. K. (1993) A protein-tyrosine/serine phosphatase encoded by the genome of the cyanobacterium Nostoc commune UTEX 584. Journal of Biological Chemistry, 268 (11). pp. 7632-7635. ISSN 0021-9258

Q

Qian, M., Pan, G., Sun, L., Feng, C., Xie, Z., Tully, T., Zhong, Y. (2007) Receptor-like tyrosine phosphatase PTP10D is required for long-term memory in Drosophila. Journal of Neuroscience, 27 (16). pp. 4396-4402. ISSN 02706474 (ISSN)

R

Ramachandran, C., Aebersold, R., Tonks, N. K., Pot, D. A. (1992) Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases. Biochemistry, 31 (17). pp. 4232-4238. ISSN 0006-2960

Ramesh, M., Krishnan, N., Muthuswamy, S. K., Tonks, N. K. (2015) A Novel Phosphatidic Acid-Protein Tyrosine Phosphatase D2 Axis is Essential for ERBB2 Signaling in Mammary Epithelial Cells. Journal of Biological Chemistry, 290 (15). pp. 9646-9659. ISSN 0021-9258

Ruzinova, M. B., Schoer, R. A., Gerald, W., Egan, J. E., Pandolfi, P. P., Rafii, S., Manova, K., Mittal, V., Benezra, R. (2003) Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell, 4 (4). pp. 277-289. ISSN 1535-6108

S

Salmeen, A., Andersen, J. N., Myers, M. P., Meng, T. C., Hinks, J. A., Tonks, N. K., Barford, D. (2003) Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate. Nature, 423 (6941). pp. 769-773. ISSN 0028-0836

Salmeen, A., Andersen, J. N., Myers, M. P., Tonks, N. K., Barford, D. (2000) Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B. Molecular Cell, 6 (6). pp. 1401-1412. ISSN 1097-2765

Schwertassek, U., Haque, A., Krishnan, N., Greiner, R., Weingarten, L., Dick, T. P., Tonks, N. K. (2014) Reactivation of oxidized PTP1B and PTEN by Thioredoxin 1. Febs Journal, 281 (16). pp. 3545-3558. ISSN 1742-464X

Shen, Y., Luche, R., Wei, B., Gordon, M. L., Diltz, C. D., Tonks, N. K. (2001) Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1. Proceedings of the National Academy of Sciences of the United States of America, 98 (24). pp. 13613-13618. ISSN 0027-8424

Shual, K., Ziemiecki, A., Wilks, A. F., Harpur, A. G., Sadowski, H. B., Gilman, M. Z., Darnell, J. E. (1993) Polypeptide Signaling to the Nucleus through Tyrosine Phosphorylation of Jak and Stat Proteins. Nature, 366 (6455). pp. 580-583. ISSN 0028-0836

Stover, D. R., Charbonneau, H., Tonks, N. K., Walsh, K. A. (1991) Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells. Proceedings of the National Academy of Sciences of the United States of America, 88 (17). pp. 7704-7707. ISSN 0027-8424

Sui, X., Hyun, S. W., Kiser, T. D., Del Vecchio, R. L., Tonks, N. K., Passaniti, A., Goldblum, S. E. (2004) Receptor protein tyrosine phosphatase (PTP) mu regulates the endothelial paracellular pathway. Molecular Biology of the Cell, 15. 428A-428A. ISSN 1059-1524

Sui, X., Kiser, T. D., Del Vecchio, R. L., Young, B. A., Gregoryev, D., Garcia, J. G. N., Tonks, N. K., Goldblum, S. E. (2001) PTP mu regulates the tyrosine phosphorylation state of VE-cadherin and the pulmonary microvascular endothelial paracellular pathway. Molecular Biology of the Cell, 12. 158A-158A. ISSN 1059-1524

Sui, X. F., Kiser, T. D., Hyun, S. W., Angelini, D. J., Del Vecchio, R. L., Young, B. A., Hasday, J. D., Romer, L. H., Passaniti, A., Tonks, N. K., Goldblum, S. E. (2005) Receptor protein tyrosine phosphatase mu regulates the paracellular pathway in human lung microvascular endothelia. American Journal of Pathology, 166 (4). pp. 1247-1258. ISSN 0002-9440

Sun, H., Tonks, N. K. (1994) The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends in Biochemical Sciences, 19 (11). pp. 480-485. ISSN 0968-0004

T

Tabet, F., Schiffrin, E. L., Callera, G., He, Y., Yao, G., Ostman, A., Kappert, K., Tonks, N. K., Touyz, R. M. (2008) Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR. Circ Res, 103 (2). pp. 149-158.

Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Lees, E. K., Tonks, N. K., Mody, N., Wilson, H. M., Delibegovic, M. (2017) Genetic deletion and pharmacological inhibition of macrophage protein tyrosine phosphatase 1B (PTP1B) improves global glucose and lipid homeostasis and protects against atherosclerotic plaque formation in mouse models of atherosclerosis. Diabetic Medicine, 34 (Supple). pp. 26-27. ISSN 0742-3071

Tiganis, T., Bennett, A. M., Ravichandran, K. S., Tonks, N. K. (1998) Epidermal growth factor receptor and the adaptor protein p52(Shc) are specific substrates of T-cell protein tyrosine phosphatase. Molecular and Cellular Biology, 18 (3). pp. 1622-1634. ISSN 0270-7306

Tiganis, T., Flint, A. J., Adam, S. A., Tonks, N. K. (1997) Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97. Journal of Biological Chemistry, 272 (34). pp. 21548-21557. ISSN 0021-9258

Tiganis, T., Kemp, B. E., Tonks, N. K. (1999) The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling. Journal of Biological Chemistry, 274 (39). pp. 27768-27775. ISSN 0021-9258

Tonks, N. (2012) HARNESSING REDOX REGULATION OF PROTEIN TYROSINE PHOSPHATASES. Free Radical Biology and Medicine, 53 (Supple). S3-S3. ISSN 0891-5849

Tonks, N., Krishnan, N. (2008) Regulation of Protein Tyrsoine Phosphatase by Hydrogen Sulphide. Free Radical Biology and Medicine, 45 (Suppl.). S18-S19. ISSN 0891-5849

Tonks, N., Krishnan, N. (2008) Unraveling the Mechanism of Redox Regulation in Protein Tyrosine Phosphatases. Free Radical Biology and Medicine, 45 (Suppl.). S62-S62. ISSN 0891-5849

Tonks, N., Lucito, R. (2014) Global assessment of the protein tyrosine phosphatome in cancer. Cancer Research, 74 (19). ISSN 0008-5472

Tonks, N. K. (1997) From structure to function of protein tyrosine phosphatases. Faseb Journal, 11 (9). A1012-A1012. ISSN 0892-6638

Tonks, N. K. (1998) From structure to function of protein tyrosine phosphatases. Naunyn-Schmiedebergs Archives of Pharmacology, 358 (1). R377-R377. ISSN 0028-1298

Tonks, N. K. (2000) From structure to function of protein tyrosine phosphatases. Abstracts of Papers of the American Chemical Society, 219. U7-U7. ISSN 0065-7727

Tonks, N. K. (2003) PTP1B: From the sidelines to the front lines! Febs Letters, 546 (1). pp. 140-148. ISSN 0014-5793

Tonks, N. K. (1991) Plague, pox and tyrosine dephosphorylation. Curr Biol, 1 (4). pp. 259-61.

Tonks, N. K. (2013) Protein Tyrosine Phosphatases: Critical Regulators of Signaling in Cancer. Faseb Journal, 27 (1). ISSN 0892-6638

Tonks, N. K. (2013) Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction. Febs Journal, 280 (2). pp. 346-378. ISSN 1742464X

Tonks, N. K. (1994) Protein tyrosine phosphatases and the control of the cellular signalling responses. Faseb Journal, 8 (7). A1377-A1377. ISSN 0892-6638

Tonks, N. K. (1996) Protein tyrosine phosphatases and the control of the cellular signalling responses. Faseb Journal, 10 (6). P13-P13. ISSN 0892-6638

Tonks, N. K. (2006) Protein tyrosine phosphatases: from genes, to function, to disease. Nat Rev Mol Cell Biol, 7 (11). pp. 833-46. ISSN 1471-0072 (Print)

Tonks, N. K. (2005) Redox redux: revisiting PTPs and the control of cell signaling. Cell, 121 (5). pp. 667-70. ISSN 0092-8674 (Print)

Tonks, N. K. (2007) The protein tyrosine phosphatase superfamily of enzymes. Toxicology Letters, 172 (Supple). S10-S11. ISSN 0378-4274

Tonks, N. K., Diltz, C. D., Fischer, E. H. (1991) Purification and assay of CD45: an integral membrane protein-tyrosine phosphatase. Methods in Enzymology, 201. pp. 442-451. ISSN 0076-6879

Tonks, N. K., Diltz, C. D., Fischer, E. H. (1991) Purification of protein-tyrosine phosphatases from human placenta. Methods in Enzymology, 201. pp. 427-442. ISSN 0076-6879

Tonks, N. K., Flint, A. J., Gebbink, M. F., Sun, H., Yang, Q. (1993) Signal transduction and protein tyrosine dephosphorylation. Adv Second Messenger Phosphoprotein Res, 28. pp. 203-10. ISSN 1040-7952 (Print)

Tonks, N. K., Muthuswamy, S. K. (2007) A Brake Becomes an Accelerator: PTP1B-A New Therapeutic Target for Breast Cancer. Cancer Cell, 11 (3). pp. 214-6. ISSN 1535-6108 (Print)

Tonks, N. K., Neel, B. G. (2001) Combinatorial control of the specificity of protein tyrosine phosphatases. Current Opinion in Cell Biology, 13 (2). pp. 182-195. ISSN 0955-0674

Tonks, N. K., Neel, B. G. (1996) From form to function: Signaling by protein tyrosine phosphatases. Cell, 87 (3). pp. 365-368. ISSN 0092-8674

Tonks, N. K., Yang, Q., Flint, A. J., Gebbink, M. F., Franza, B. R., Hill, D. E., Sun, H., Brady-Kalnay, S. M. (1992) Protein tyrosine phosphatases: the problems of a growing family. Cold Spring Harbor Symposia on Quantitative Biology, 57. pp. 87-94. ISSN 0091-7451

Tonks, N. K., Yang, Q., Guida, P. (1991) Structure, regulation, and function of protein tyrosine phosphatases. Cold Spring Harbor Symposia on Quantitative Biology, 56. pp. 265-273. ISSN 0091-7451

Tonks, N. K. (2012) Talk from Nick Tonks at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Y

Yang, M., Haase, A. D., Huang, F. K., Coulis, G., Rivera, K. D., Dickinson, B. C., Chang, C. J., Pappin, D. J., Neubert, T. A., Hannon, G. J., Boivin, B., Tonks, N. K. (2014) Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence. Mol Cell, 55 (5). pp. 782-790. ISSN 1097-2765

Yang, Q., Co, D., Sommercorn, J., Tonks, N. K. (1993) Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase. Journal of Biological Chemistry, 268 (9). pp. 6622-6628. ISSN 0021-9258

Yang, Q., Tonks, N. K. (1991) Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin. Proceedings of the National Academy of Sciences of the United States of America, 88 (14). pp. 5949-5953. ISSN 0027-8424

Z

Zander, N. F., Lorenzen, J. A., Cool, D. E., Tonks, N. K., Daum, G., Krebs, E. G., Fischer, E. H. (1991) Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system. Biochemistry, 30 (28). pp. 6964-6970. ISSN 0006-2960

Zhang, S., Fan, G., Hao, Y., Hammell, M., Wilkinson, J. E., Tonks, N. K. (2017) Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase. Genes Dev, 31 (19). pp. 1939-57. ISSN 0890-9369

Zhang, S. H., Eckberg, W. R., Yang, Q., Samatar, A. A., Tonks, N. K. (1995) Biochemical characterization of a human band 4.1-related protein-tyrosine phosphatase, PTPH1. Journal of Biological Chemistry, 270 (34). pp. 20067-20072. ISSN 0021-9258

Zhang, S. H., Kobayashi, R., Graves, P. R., Piwnica-Worms, H., Tonks, N. K. (1997) Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3 beta protein. Journal of Biological Chemistry, 272 (43). pp. 27281-27287. ISSN 0021-9258

Zhang, S. H., Liu, J. P., Kobayashi, R., Tonks, N. K. (1999) Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1. Journal of Biological Chemistry, 274 (25). pp. 17806-17812. ISSN 0021-9258

Zhang, S. H., Tonks, N. K. (1996) Phosphorylation-dependent association of band 4.1-related protein tyrosine phosphatase PTPH1 and 14-3-3B. Molecular Biology of the Cell, 7. p. 83. ISSN 1059-1524

This list was generated on Sat Dec 16 23:22:57 2017 EST.
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