Items where Subject is "kinase"

A

Abate, C., Marshak, D. R., Curran, T. (December 1991) Fos is phosphorylated by p34cdc2, cAMP-dependent protein kinase and protein kinase C at multiple sites clustered within regulatory regions. Oncogene, 6 (12). pp. 2179-2185. ISSN 0950-9232

Alcorta, D. A., Xiong, Y., Phelps, D., Hannon, G., Beach, D., Barrett, J. C. (November 1996) Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 13742-13747. ISSN 00278424 (ISSN)

Allemand, E., Guil, S., Myers, M., Moscat, J., Caceres, J. F., Krainer, A. R. (March 2005) Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. Proc Natl Acad Sci U S A, 102 (10). pp. 3605-10. ISSN 0027-8424 (Print)

Allemand, E., Hastings, M. L., Murray, M. V., Myers, M. P., Krainer, A. R. (July 2007) Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid-binding protein YB-1. Nat Struct Mol Biol, 14 (7). pp. 630-638. ISSN 1545-9993 (Print)

Arrazola, M. S., Saquel, C., Catalan, R. J., Barrientos, S. A., Hernandez, D. E., Catenaccio, A., Court, F. A. (May 2019) Axonal degeneration is mediated by necroptosis activation Necroptosis mediates axonal degeneration. J Neurosci, 39 (20). pp. 3832-2844. ISSN 0270-6474

B

Bagrodia, S., Taylor, S. J., Jordon, K. A., Van Aelst, L., Cerione, R. A. (September 1998) A novel regulator of p21-activated kinases. Journal of Biological Chemistry, 273 (37). pp. 23633-23636. ISSN 0021-9258

Baker, S. J., Kerppola, T. K., Luk, D., Vandenberg, M. T., Marshak, D. R., Curran, T., Abate, C. (October 1992) Jun Is Phosphorylated by Several Protein-Kinases at the Same Sites That Are Modified in Serum-Stimulated Fibroblasts. Molecular and Cellular Biology, 12 (10). pp. 4694-4705. ISSN 0270-7306

Balbín, M., Hannon, G. J., Pendás, A. M., Ferrando, A. A., Vizoso, F., Fueyo, A., López-Otín, C. (1996) Functional analysis of a p21(WAF1,CIP1,SDI1) mutant (Arg 94 → Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases. Journal of Biological Chemistry, 271 (26). pp. 15782-15786. ISSN 00219258 (ISSN)

Bayer, M., Nawy, T., Giglione, C., Galli, M., Meinnel, T., Lukowitz, W. (March 2009) Paternal Control of Embryonic Patterning in Arabidopsis thaliana. Science, 323 (5920). pp. 1485-1488. ISSN 0036-8075

Beach, D., Serrano, M., Hannon, G. J. (February 1994) P16(Ink4) - an Specific Inhibitor of the Cdk4/Cyclin-D Kinase. Journal of Cellular Biochemistry, Supp (18C). p. 161. ISSN 0730-2312

Bivona, T. G., Hieronymus, H., Parker, J., Chang, K., Taron, M., Rosell, R., Moonsamy, P., Dahlman, K., Miller, V. A., Costa, C., Hannon, G. J., Sawyers, C. L. (March 2011) FAS and NF-kappa B signalling modulate dependence of lung cancers on mutant EGFR. Nature, 471 (7339). pp. 523-526. ISSN 0028-0836

Boato, Francesco, Guan, Xiaofei, Zhu, Yanjie, Ryu, Youngjae, Voutounou, Mariel, Rynne, Christopher, Freschlin, Chase R, Zumbo, Paul, Betel, Doron, Matho, Katie, Makarov, Sergey N, Wu, Zhuhao, Son, Young-Jin, Nummenmaa, Aapo, Huang, Josh Z, Edwards, Dylan J, Zhong, Jian (January 2023) Activation of MAP2K signaling by genetic engineering or HF-rTMS promotes corticospinal axon sprouting and functional regeneration. Science Translational Medicine, 15 (677). eabq6885. ISSN 1946-6234 (Public Dataset)

Bodineau, Clément, Tomé, Mercedes, Courtois, Sarah, Costa, Ana SH, Sciacovelli, Marco, Rousseau, Benoit, Richard, Elodie, Vacher, Pierre, Parejo-Pérez, Carlos, Bessede, Emilie, Varon, Christine, Soubeyran, Pierre, Frezza, Christian, Murdoch, Piedad Del Socorro, Villar, Victor H, Durán, Raúl V (August 2021) Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis. Nature Communications, 12 (1). p. 4814. ISSN 2041-1723

Boehm, J., Malinow, R. (December 2005) AMPA receptor phosphorylation during synaptic plasticity. Biochem Soc Trans, 33 (Pt 6). pp. 1354-6. ISSN 0300-5127 (Print)

Boivin, B., Chaudhary, F., Dickinson, B. C., Haque, A., Pero, S. C., Chang, C. J., Tonks, N. K. (November 2013) Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein mediated mammary epithelial cell motility. Journal of Biological Chemistry, 288 (52). pp. 36926-36935. ISSN 00219258 (ISSN)

Bommert, P., Lunde, C., Nardmann, J., Vollbrecht, E., Running, M., Jackson, D. P., Hake, S., Werr, W. (March 2005) Thick tassel dwarf1 encodes a putative maize ortholog of the Arabidopsis CLAVATA1 leucine-rich repeat receptor-like kinase. Development, 132 (6). pp. 1235-1245. ISSN 0950-1991

Bonham, ChristopherA, Mandati, Vinay, Singh, RakeshK, Pappin, DarrylJ, Tonks, NicholasK (March 2023) Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks. Journal of Biological Chemistry. p. 104582. ISSN 0021-9258

Boutchueng-Djidjou, M., Belleau, P., Bilodeau, N., Fortier, S., Bourassa, S., Droit, A., Elowe, S., Faure, R. L. (October 2018) A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes. PLoS One, 13 (10). e0205180. ISSN 1932-6203

Brondello, J. M., McKenzie, F. R., Sun, H., Tonks, N. K., Pouyssegur, J. (May 1995) Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts. Oncogene, 10 (10). pp. 1895-1904. ISSN 0950-9232

Broughton, S. J., Tully, T., Greenspan, R. J. (January 2003) Conditioning deficits of CaM-kinase transgenic Drosophila melanogaster in a new excitatory courtship assay. Journal of Neurogenetics, 17 (1). pp. 91-102. ISSN 0167-7063

Brägelmann, Johannes, Lorenz, Carina, Borchmann, Sven, Nishii, Kazuya, Wegner, Julia, Meder, Lydia, Ostendorp, Jenny, Ast, David F, Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A, Plenker, Dennis, Klein, Sebastian, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K, Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D'Rozario, Joshua, Thomas, Emily S, Li, Henry, Schmitt, Clemens A, George, Julie, Thomas, Roman K, von Karstedt, Silvia, Hartmann, Gunther, Büttner, Reinhard, Ullrich, Roland T, Siveke, Jens T, Ohashi, Kadoaki, Schlee, Martin, Sos, Martin L (September 2021) MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nature Communications, 12 (1). p. 5505. ISSN 2041-1723

C

Cameron, S., Levin, L., Zoller, M., Wigler, M. H. (May 1988) cAMP-independent control of sporulation, glycogen metabolism, and heat shock resistance in S. cerevisiae. Cell, 53 (4). pp. 555-66. ISSN 0092-8674

Carmel, G., Kuret, J. (June 1992) A solid-phase screen for protein kinase substrate selectivity. Anal Biochem, 203 (2). pp. 274-80. ISSN 0003-2697 (Print)0003-2697 (Linking)

Carmel, G., Leichus, B., Cheng, X., Patterson, S. D., Mirza, U., Chait, B. T., Kuret, J. (March 1994) Expression, purification, crystallization, and preliminary x-ray analysis of casein kinase-1 from Schizosaccharomyces pombe. J Biol Chem, 269 (10). pp. 7304-9. ISSN 0021-9258 (Print)

Carroll, D., Marshak, D. R. (May 1989) Serum-stimulated cell growth causes oscillations in casein kinase II activity. J Biol Chem, 264 (13). pp. 7345-8. ISSN 1083-351X

Chen, M. H., Pratt, C. P., Zeeman, M. E., Schultz, N., Taylor, B. S., O'Neill, A., Castillo-Martin, M., Nowak, D. G., Naguib, A., Grace, D. M., Murn, J., Navin, N., Atwal, G. S., Sander, C., Gerald, W. L., Cordon-Cardo, C., Newton, A. C., Carver, B. S., Trotman, L. C. (August 2011) Identification of PHLPP1 as a Tumor Suppressor Reveals the Role of Feedback Activation in PTEN-Mutant Prostate Cancer Progression. Cancer Cell, 20 (2). pp. 173-186. ISSN 1535-6108

Chester, N., Marshak, D. R. (April 1994) Characterization of Casein Kinase-Ii Isoforms in Hela-Cells. Faseb Journal, 8 (7). A1391-A1391. ISSN 0892-6638

Clark, J. W., Camidge, D. R., Kwak, E. L., Maki, R. G., Shapiro, G. I., Chen, I., Tan, W., Randolph, S., Christensen, J. G., Ozeck, M., Tang, Y., Wilner, K. D., Salgia, R. (January 2020) Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer. Future Oncol, 16 (1). pp. 4289-4301. ISSN 1479-6694

Clarke, P. A., Pe'ery, T., Ma, Y., Mathews, M. B. (October 1994) Structural features of adenovirus 2 virus-associated RNA required for binding to the protein kinase DAI. Nucleic Acids Res, 22 (21). pp. 4364-74. ISSN 0305-1048 (Print)

Cline, H. T., Constantine-Paton, M. (June 1990) The differential influence of protein kinase inhibitors on retinal arbor morphology and eye-specific stripes in the frog retinotectal system. Neuron, 4 (6). pp. 899-908. ISSN 0896-6273 (Print)0896-6273 (Linking)

Coghlan, V. M., Perrino, B. A., Howard, M., Langeberg, L. K., Hicks, J. B., Gallatin, W. M., Scott, J. D. (1995) Association of protein kinase A and protein phosphatase 2B with a common anchoring protein. Science, 267 (5195). pp. 108-111. ISSN 00368075 (ISSN)

Connell, L. E., Helfman, D. M. (June 2006) Myosin light chain kinase plays a role in the regulation of epithelial cell survival. J Cell Sci, 119 (Pt 11). pp. 2269-81. ISSN 0021-9533 (Print)

Connelly, Carla J, Vidal-Cardenas, Sofia, Goldsmith, Stephanie, Greider, Carol W (November 2021) The Bur1 cyclin-dependent kinase regulates telomere length in Saccharomyces cerevisiae. Yeast. ISSN 0749-503X

Connolly, T., Caligiuri, M., Beach, D. (June 1997) The Cdc2 protein kinase controls Cdc10/Sct1 complex formation. Molecular Biology of the Cell, 8 (6). pp. 1105-15. ISSN 1059-1524 (Print)

Crompton, J. G., Sukumar, M., Roychoudhuri, R., Clever, D., Gros, A., Eil, R. L., Tran, E., Hanada, K., Yu, Z., Palmer, D. C., Kerkar, S. P., Michalek, R. D., Upham, T., Leonardi, A., Acquavella, N., Wang, E., Marincola, F. M., Gattinoni, L., Muranski, P., Sundrud, M. S., Klebanoff, C. A., Rosenberg, S. A., Fearon, D. T., Restifo, N. P. (January 2015) Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics. Cancer Res, 75 (2). pp. 296-305. ISSN 0008-5472

D

Dagnell, M., Frijhoff, J., Pader, I., Augsten, M., Boivin, B., Xu, J., Mandal, P. K., Tonks, N. K., Hellberg, C., Conrad, M., Arnér, E. S. J., Östman, A. (August 2013) Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-ß receptor tyrosine kinase signaling. Proceedings of the National Academy of Sciences of the United States of America, 110 (33). pp. 13398-13403. ISSN 00278424

Davies, C. C., Harvey, E., McMahon, R. F. T., Finegan, K. G., Connor, F., Davis, R. J., Tuveson, D. A., Tournier, C. (April 2014) Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Cancer Research, 74 (12). pp. 3344-3356. ISSN 15387445

Davis, L. E., Bolejack, V., Ryan, C. W., Ganjoo, K. N., Loggers, E. T., Chawla, S., Agulnik, M., Livingston, M. B., Reed, D., Keedy, V., Rushing, D., Okuno, S., Reinke, D. K., Riedel, R. F., Attia, S., Mascarenhas, L., Maki, R. G. (June 2019) Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma. J Clin Oncol, 37 (16). pp. 1424-1431. ISSN 0732-183x

Degenhardt, Y. Y., Wooster, R., McCombie, R. W., Lucito, R., Powers, S. (February 2008) High-content analysis of cancer genome DNA alterations. Current Opinion in Genetics & Development, 18 (1). pp. 68-72.

Delas, M. J., Jackson, B. T., Kovacevic, T., Vangelisti, S., Munera Maravilla, E., Wild, S. A., Stork, E. M., Erard, N., Knott, S. R. V., Hannon, G. J. (April 2019) lncRNA Spehd Regulates Hematopoietic Stem and Progenitor Cells and Is Required for Multilineage Differentiation. Cell Rep, 27 (3). 719-729.e6.

Demetrick, D. J., Zhang, H., Beach, D. H. (1994) Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes. Cytogenet Cell Genet, 66 (1). pp. 72-4. ISSN 0301-0171 (Print)

Dent, P., Booth, L., Roberts, J. L., Liu, J., Poklepovic, A., Lalani, A. S., Tuveson, D., Martinez, J., Hancock, J. F. (June 2019) Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. Oncogene. ISSN 0950-9232

Diaz-Nido, J., Mizuno, K., Nawa, H., Marshak, D. R. (1994) Regulation of protein kinase CK2 isoform expression during rat brain development. Cell Mol Biol Res, 40 (5-6). pp. 581-5. ISSN 0968-8773 (Print)

Doria, M., Klein, N., Lucito, R., Schneider, R. J. (October 1995) The hepatitis B virus HBx protein is a dual specificity cytoplasmic activator of Ras and nuclear activator of transcription factors. Embo J, 14 (19). pp. 4747-57.

Draviam, V. M., Stegmeier, F., Nalepa, G., Sowa, M. E., Chen, J., Liang, A., Hannon, G. J., Sorger, P. K., Harper, J. W., Elledge, S. J. (May 2007) A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling. Nature Cell Biology, 9 (5). pp. 556-564. ISSN 1465-7392

Drier, E. A., Tello, M. K., Cowan, M., Wu, P., Blace, N., Sacktor, T. C., Yin, J. C. P. (April 2002) Memory enhancement and formation by atypical PKM activity in Drosophila melanogaster. Nature Neuroscience, 5 (4). pp. 316-324. ISSN 1097-6256

Du, J., Hannon, G. J. (June 2004) Suppression of p160ROCK bypasses cell cycle arrest after Aurora-A/STK15 depletion. Proc Natl Acad Sci U S A, 101 (24). pp. 8975-80. ISSN 0027-8424 (Print)

Du, J., Hannon, G. J. (2002) The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1. Nucleic Acids Research, 30 (24). pp. 5465-5475. ISSN 03051048 (ISSN)

Dutta, A., Din, S., Brill, S. J., Stillman, B. (1991) Phosphorylation of replication protein A: A role for cdc2 kinase in G1/S regulation. Cold Spring Harbor Symposia on Quantitative Biology, 56. pp. 315-324. ISSN 00917451 (ISSN)

E

Egeblad, M., Mortensen, O. H., van Kempen, L. C., Jaattela, M. (February 2001) BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells. Biochemical and biophysical research communications, 281 (1). pp. 25-31. ISSN 0006-291X (Print)0006-291x

Eifert, C., Wang, X., Kokabee, L., Kourtidis, A., Jain, R., Gerdes, M. J., Conklin, D. S. (October 2013) A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis. Genes Chromosomes and Cancer, 52 (10). pp. 961-975. ISSN 10452257

F

Fischer, E. H., Charbonneau, H., Cool, D. E., Tonks, N. K. (1992) Tyrosine phosphatases and their possible interplay with tyrosine kinases. Ciba Foundation Symposia, 164. pp. 132-144. ISSN 0300-5208

Foronda, M., Tarumoto, Y., Schatoff, E. M., Leach, B. I., Diaz, B. J., Zimmerman, J., Goswami, S., Shusterman, M., Vakoc, C. R., Dow, L. E. (December 2019) Tankyrase inhibition sensitizes cells to CDK4 blockade. PLoS One, 14 (12). e0226645. ISSN 1932-6203

Franchin, Cinzia, Cesaro, Luca, Salvi, Mauro, Millioni, Renato, Iori, Elisabetta, Cifani, Paolo, James, Peter, Arrigoni, Giorgio, Pinna, Lorenzo (June 2015) Quantitative analysis of a phosphoproteome readily altered by the protein kinase CK2 inhibitor quinalizarin in HEK-293T cells. BBA: Proteins and Proteomics, 1854 (6). pp. 609-623. ISSN 1570-9639

Funk, J. O., Waga, S., Harry, J. B., Espling, E., Stillman, B., Galloway, D. A. (August 1997) Inhibition of CDK activity and PCNA-dependent DNA replication by p21 is blocked by interaction with the HPV-16 E7 oncoprotein. Genes and Development, 11 (16). pp. 2090-2100. ISSN 08909369 (ISSN)

G

Gilman, M. (February 1993) Viral Transactivation - Pleiotropy and Henchman-X. Nature, 361 (6414). pp. 687-688. ISSN 0028-0836

Giordano, A., Scheppler, J., Lee, J., Ross, J., Mak, G., Franza, B. R. Jr (1991) Cell-Cycle Dependent Modulation of an E1a-Immune Complex Histone H1 Specific Kinase Activity. Journal of Cellular Biochemistry , 47 (Suppl ). p. 68.

Glass, D. B., Feller, M. J., Levin, L. R., Walsh, D. A. (February 1992) Structural basis for the low affinities of yeast cAMP-dependent and mammalian cGMP-dependent protein kinases for protein kinase inhibitor peptides. Biochemistry, 31 (6). pp. 1728-34. ISSN 0006-2960 (Print)0006-2960 (Linking)

Goldberg, M., Stucki, M., Falck, J., D'Amours, D., Rahman, D., Pappin, D., Bartek, J., Jackson, S. P. (February 2003) MDC1 is required for the intra-S-phase DNA damage checkpoint. Nature, 421 (6926). pp. 952-6. ISSN 0028-0836 (Print)0028-0836 (Linking)

Green, S. R., Mathews, M. B. (December 1992) Two RNA-binding motifs in the double-stranded RNA-activated protein kinase, DAI. Genes Dev, 6 (12B). pp. 2478-90. ISSN 0890-9369 (Print)0890-9369 (Linking)

H

Hannon, G. J., Casso, D., Beach, D. (1994) KAP: A dual specificity phosphatase that interacts with cyclin-dependent kinases. Proceedings of the National Academy of Sciences of the United States of America, 91 (5). pp. 1731-1735. ISSN 00278424 (ISSN)

Hayashi, Y., Shi, S. H., Esteban, J. A., Piccini, A., Poncer, J. C., Malinow, R. (March 2000) Driving AMPA receptors into synapses by LTP and CaMKII: Requirement for GluR1 and PDZ domain interaction. Science, 287 (5461). pp. 2262-2267. ISSN 0036-8075

Hemmings, B. A., Restuccia, D., Tonks, N. K. (April 2009) Targeting the Kinome II. Curr Opin Cell Biol, 21 (2). pp. 135-139.

Herrmann, C. H., Su, L. K., Harlow, E. (November 1991) Adenovirus E1A is associated with a serine/threonine protein kinase. Journal of Virology, 65 (11). pp. 5848-5859. ISSN 0022-538x

Hoekstra, M. F., Dhillon, N., Carmel, G., Demaggio, A. J., Lindberg, R. A., Hunter, T., Kuret, J. (August 1994) Budding and Fission Yeast Casein Kinase-I Isoforms Have Dual-Specificity Protein-Kinase Activity. Molecular Biology of the Cell, 5 (8). pp. 877-886. ISSN 1059-1524

Hossain, Manzar, Bhalla, Kuhulika, Stillman, Bruce (March 2021) Multiple, short protein binding motifs in ORC1 and CDC6 control the initiation of DNA replication. Molecular Cell. ISSN 1097-2765

Hu, Q. J., Lees, J. A., Buchkovich, K. J., Harlow, E. (March 1992) The retinoblastoma protein physically associates with the human cdc2 kinase. Mol Cell Biol, 12 (3). pp. 971-80. ISSN 0270-7306 (Print)0270-7306 (Linking)

Hudson, J. D., Feilotter, H., Lingner, C., Rowley, R., Young, P. G. (1991) stf1: a new suppressor of the mitotic control gene, cdc25, in Schizosaccharomyces pombe. Cold Spring Harb Symp Quant Biol, 56. pp. 599-604. ISSN 0091-7451 (Print)0091-7451 (Linking)

Hörmann, A., Hopfgartner, B., Köcher, T., Corcokovic, M., Krammer, T., Reiser, C., Bader, G., Shi, J., Ehrenhöfer, K., Wöhrle, S., Schweifer, N., Vakoc, C. R., Kraut, N., Pearson, M., Petronczki, M., Neumüller, R. A. (June 2018) RIOK1 kinase activity is required for cell survival irrespective of MTAP status. Oncotarget, 9 (47). pp. 28625-28637. ISSN 1949-2553

J

Janas, J. A., Van Aelst, L. (May 2011) Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Molecular and Cellular Biology, 31 (13). pp. 2552-2565. ISSN 0270-7306

Jia, H., Li, M., Li, W., Liu, L., Jian, Y., Yang, Z., Shen, X., Ning, Q., Du, Y., Zhao, R., Jackson, D., Yang, X., Zhang, Z. (February 2020) A Serine/Threonine Protein Kinase Encoding Gene KERNEL NUMBER PER ROW6 Regulates Maize Grain Yield. Nature Communications, 11 (988). pp. 1-11. ISSN 2041-1723 (Public Dataset)

Jimenez-Garcia, L. F., Green, S. R., Mathews, M. B., Spector, D. L. (1993) Organization of the double-stranded RNA-activated protein kinase DAI and virus-associated VA RNAI in adenovirus-2-infected HeLa cells. Journal of Cell Science, 106. pp. 11-22. ISSN 0021-9533 (ISSN)

Johnson, K. E., Cameron, S., Toda, T., Wigler, M. H., Zoller, M. J. (1987) Expression in Escherichia coli of BCY1, the regulatory subunit of cyclic AMP-dependent protein kinase from Saccharomyces cerevisiae. Journal of Biological Chemistry, 262 (18). pp. 8636-8642.

Joneson, T., McDonough, M., Bar-Sagi, D., Van Aelst, L. (November 1996) RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science, 274 (5291). pp. 1374-1376. ISSN 0036-8075

Joneson, T., White, M. A., Wigler, M. H., Bar-Sagi, D. (February 1996) Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS. Science, 271 (5250). pp. 810-812. ISSN 0036-8075

K

Kannan, N., Neuwald, A. F. (May 2004) Evolutionary clues to protein kinase structural mechanisms. Faseb Journal, 18 (8). C189-C189. ISSN 0892-6638

Kannan, N., Neuwald, A. F. (August 2004) Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2alpha. Protein Sci, 13 (8). pp. 2059-77. ISSN 0961-8368 (Print)

Karandikar, U. C., Trott, R. L., Yin, J. R., Bishop, C. P., Bidwai, A. P. (March 2004) Drosophila CK2 regulates eye morphogenesis via phosphorylation of E(spl)M8. Mechanisms of Development, 121 (3). pp. 273-286. ISSN 0925-4773

Karimi-Busheri, F., Daly, G., Robins, P., Canas, B., Pappin, D. J., Sgouros, J., Miller, G. G., Fakhrai, H., Davis, E. M., Le Beau, M. M., Weinfeld, M. (August 1999) Molecular characterization of a human DNA kinase. Journal of Biological Chemistry, 274 (34). pp. 24187-94. ISSN 0021-9258 (Print)0021-9258 (Linking)

Khosravi-Far, R., White, M. A., Westwick, J. K., Solski, P. A., Chrzanowska-Wodnicka, M., Van Aelst, L., Wigler, M. H., Der, C. J. (July 1996) Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol Cell Biol, 16 (7). pp. 3923-33. ISSN 0270-7306 (Print)

Kim, S., Telo-Ruiz, M., Yin, J., Wodarz, A. (March 2003) Functional analysis of atypical protein kinase C in Drosophila oogenesis. European Journal of Cell Biology, 82 (S53). p. 83. ISSN 0171-9335

Koizumi, J., Okamoto, Y., Onogi, H., Mayeda, A., Krainer, A. R., Hagiwara, M. (April 1999) The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs). Journal of Biological Chemistry, 274 (16). pp. 11125-11131. ISSN 0021-9258

Kondo, S., Lu, Y., Debbas, M., Lin, A. W., Sarosi, I., Itie, A., Wakeham, A., Tuan, J., Saris, C., Elliott, G., Ma, W. L., Benchimol, S., Lowe, S. W., Mak, T. W., Thukral, S. K. (April 2003) Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). Proceedings of the National Academy of Sciences of the United States of America, 100 (9). pp. 5431-5436. ISSN 0027-8424

Kostura, M., Mathews, M. B. (April 1989) Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAI. Molecular & Cellular Biology, 9 (4). pp. 1576-86. ISSN 0270-7306

Kuret, J., Pflugrath, J. W. (October 1991) Crystallization and preliminary X-ray analysis of the cAMP-dependent protein kinase catalytic subunit from Saccharomyces cerevisiae. Biochemistry, 30 (43). pp. 10595-600. ISSN 0006-2960 (Print)0006-2960 (Linking)

Kwoh, T. J., Zipser, D., Wigler, M. H. (1983) Mutational analysis of the cloned chicken thymidine kinase gene. J Mol Appl Genet, 2 (2). pp. 191-200. ISSN 0271-6801 (Print)

L

Lamb, N. J., Fernandez, A., Conti, M. A., Adelstein, R., Glass, D. B., Welch, W. J., Feramisco, J. R. (June 1988) Regulation of actin microfilament integrity in living nonmuscle cells by the cAMP-dependent protein kinase and the myosin light chain kinase. J Cell Biol, 106 (6). pp. 1955-71. ISSN 0021-9525

Lamb, N. J., Fernandez, A., Feramisco, J. R., Welch, W. J. (June 1989) Modulation of vimentin containing intermediate filament distribution and phosphorylation in living fibroblasts by the cAMP-dependent protein kinase. J Cell Biol, 108 (6). pp. 2409-22. ISSN 0021-9525

Lee, S. B., Green, S. R., Mathews, M. B., Esteban, M. (October 1994) Activation of the Double-Stranded-Rna (Dsrna)-Activated Human Protein-Kinase in-Vivo in the Absence of Its Dsrna Binding Domain. Proceedings of the National Academy of Sciences of the United States of America, 91 (22). pp. 10551-10555. ISSN 0027-8424

Levin, L. R., Kuret, J., Johnson, K. E., Powers, S., Cameron, S., Michaeli, T., Wigler, M. H., Zoller, M. J. (April 1988) A mutation in the catalytic subunit of cAMP-dependent protein kinase that disrupts regulation. Science, 240 (4848). pp. 68-70.

Levin, L. R., Zoller, M. J. (March 1990) Association of catalytic and regulatory subunits of cyclic AMP-dependent protein kinase requires a negatively charged side group at a conserved threonine. Mol Cell Biol, 10 (3). pp. 1066-75. ISSN 0270-7306 (Print)0270-7306 (Linking)

Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., Parsons, R. (December 1998) The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Research, 58 (24). pp. 5667-5672. ISSN 0008-5472

Li, K., Zhou, T., Liao, L., Yang, Z., Wong, C., Henn, F., Malinow, R., Yates Iii, J. R., Hu, H. (August 2013) βCaMKII in lateral habenula mediates core symptoms of depression. Science, 341 (6149). pp. 1016-1020. ISSN 00368075 (ISSN)

Li, Bing, An, Wenbin, Wang, Hua, Baslan, Timour, Mowla, Shoron, Krishnan, Aishwarya, Xiao, Wenbin, Koche, Richard Patrick, Liu, Ying, Cai, Sheng F, Xiao, Zhijian, Derkach, Andriy, Iacobucci, Ilaria, Mullighan, Charles G, Helin, Kristian, Lowe, Scott W, Levine, Ross L, Rampal, Raajit K (April 2022) BMP2/SMAD pathway activation in JAK2/p53-mutant Megakaryocyte/Erythroid Progenitors Promotes Leukemic Transformation. Blood. ISSN 0006-4971

Li, Xiang, Huang, Chun-Hao, Sánchez-Rivera, Francisco J, Kennedy, Margaret C, Tschaharganeh, Darjus F, Morris, John P, Montinaro, Antonella, O'Rourke, Kevin P, Banito, Ana, Wilkinson, John E, Chen, Chi-Chao, Ho, Yu-Jui, Dow, Lukas E, Tian, Sha, Luan, Wei, de Stanchina, Elisa, Zhang, Tinghu, Gray, Nathanael S, Walczak, Henning, Lowe, Scott W (April 2022) A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets. Proceedings of the National Academy of Sciences of USA, 119 (17). e2110557119. ISSN 0027-8424

Li, Zhengnian, Ishida, Ryosuke, Liu, Yan, Wang, Jinhua, Li, Yina, Gao, Yang, Jiang, Jie, Che, Jianwei, Sheltzer, Jason M, Robers, Matthew B, Zhang, Tinghu, Westover, Kenneth D, Nabet, Behnam, Gray, Nathanael S (May 2022) Synthesis and Structure-Activity relationships of cyclin-dependent kinase 11 inhibitors based on a diaminothiazole scaffold. European Journal of Medicinal Chemistry, 238. p. 114433. ISSN 0223-5234

Lin, A., Giuliano, C. J., Palladino, A., John, K. M., Abramowicz, C., Yuan, M. L., Sausville, E. L., Lukow, D. A., Liu, L., Chait, A. R., Galluzzo, Z. C., Tucker, C., Sheltzer, J. M. (September 2019) Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials. Sci Transl Med, 11 (509). ISSN 1946-6234

Lin, Shan, Tarumoto, Yusuke, Wang, Jinhua, Milazzo, Joseph, Xu, Yali, Gray, Nathanael, Vakoc, Christopher, Stegmaier, Kimberly (November 2019) Targeting Salt-Inducible Kinase 3 As a Therapeutic Approach for Acute Myeloid Leukemia. In: American Society of Hematology.

Lisman, J., Schulman, H., Cline, H. (March 2002) The molecular basis of CaMKII function in synaptic and behavioural memory. Nature Reviews Neuroscience, 3 (3). pp. 175-190. ISSN 1471-0048

Liu, P. H., Shah, R. B., Li, Y., Arora, A., Ung, P. M., Raman, R., Gorbatenko, A., Kozono, S., Zhou, X. Z., Brechin, V., Barbaro, J. M., Thompson, R., White, R. M., Aguirre-Ghiso, J. A., Heymach, J. V., Lu, K. P., Silva, J. M., Panageas, K. S., Schlessinger, A., Maki, R. G., Skinner, H. D., de Stanchina, E., Sidi, S. (January 2019) An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy. Nat Cell Biol, 21 (2). pp. 203-213. ISSN 1465-7392

Lowe, S. W., Sherr, C. J. (February 2003) Tumor suppression by Ink4a-Arf: progress and puzzles. Current Opinion in Genetics & Development, 13 (1). pp. 77-83. ISSN 0959-437X

Lu, Y. B., Lu, Y. S., Shuai, Y. C., Feng, C. H., Tully, T., Xie, Z. P., Zhong, Y., Zhou, H. M. (August 2007) The AKAP Yu is required for olfactory long-term memory formation in Drosophila. Proc Natl Acad Sci U S A, 104 (34). pp. 13792-13797. ISSN 0027-8424

Luckett, Kathleen A, Cracchiolo, Jennifer R, Krishnamoorthy, Gnana P, Leandro-Garcia, Luis Javier, Nagarajah, James, Saqcena, Mahesh, Lester, Rona, Im, Soo Y, Zhao, Zhen, Lowe, Scott W, de Stanchina, Elisa, Sherman, Eric J, Ho, Alan L, Leach, Steven D, Knauf, Jeffrey A, Fagin, James A (May 2021) Co-inhibition of SMAD and MAPK signaling enhances 124I uptake in BRAF-mutant thyroid cancers. Endocrine-Related Cancer, 28 (6). pp. 391-402. ISSN 1351-0088

Luke, J. J., D'Adamo, D. R., Dickson, M. A., Keohan, M. L., Carvajal, R. D., Maki, R. G., de Stanchina, E., Musi, E., Singer, S., Schwartz, G. K. (May 2012) The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial. Clin Cancer Res, 18 (9). pp. 2638-47. ISSN 1078-0432 (Print)1078-0432 (Linking)

Lundgren, K., Dembski, M., Beach, D. (1990) Identification and Characterization of a Novel Mitotic Inhibitory Kinase in Schizosaccharomyces-Pombe. Journal of Cell Biology, 111 (5 PART). 93A.

Luscher, B., Brizuela, L., Beach, D., Eisenman, R. N. (April 1991) A role for the p34cdc2 kinase and phosphatases in the regulation of phosphorylation and disassembly of lamin B2 during the cell cycle. EMBO J, 10 (4). pp. 865-75. ISSN 0261-4189 (Print)0261-4189 (Linking)

Lyon, G. J., Mayville, P., Muir, T. W., Novick, R. P. (2000) Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor-histidine kinase, AgrC. Proceedings of the National Academy of Sciences of the United States of America, 97 (24). pp. 13330-13335. ISSN 0027-8424

M

Ma, H. (July 1993) Protein phosphorylation in plants: enzymes, substrates and regulators. Trends Genet, 9 (7). pp. 228-30. ISSN 0168-9525 (Print)

Ma, Wai Kit, Voss, Dillon M, Scharner, Juergen, Costa, Ana SH, Lin, Kuang-Ting, Jeon, Hyun Yong, Wilkinson, John E, Jackson, Michaela, Rigo, Frank, Bennett, C Frank, Krainer, Adrian R (December 2021) ASO-based PKM splice-switching therapy inhibits hepatocellular carcinoma growth. Cancer Research. canres.0948.2020-canres.0948.2020. ISSN 0008-5472

Malinow, R., Madison, D. V., Tsien, R. W. (October 1988) Persistent protein kinase activity underlying long-term potentiation. Nature, 335 (6193). pp. 820-4. ISSN 0028-0836 (Print)

Malinow, R., Tsien, R. W. (1990) Identifying and localizing protein kinases necessary for LTP. Adv Exp Med Biol, 268. pp. 301-5. ISSN 0065-2598 (Print)0065-2598 (Linking)

Malinow, R., Tsien, R. W. (1991) Long-term potentiation: postsynaptic activation of Ca(2+)-dependent protein kinases with subsequent presynaptic enhancement. Progress in Brain Research, 89. pp. 271-89. ISSN 0079-6123 (Print)0079-6123

Manche, L., Green, S. R., Schmedt, C., Mathews, M. B. (November 1992) Interactions between Double-Stranded-Rna Regulators and the Protein-Kinase Dai. Molecular and Cellular Biology, 12 (11). pp. 5238-5248. ISSN 0270-7306

Maran, A., Mathews, M. B. (May 1988) Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA. Virology, 164 (1). pp. 106-13. ISSN 0042-6822

Marcus, S., Polverino, A., Barr, M., Wigler, M. H. (August 1994) Complexes between STE5 and components of the pheromone-responsive mitogen-activated protein kinase module. Proc Natl Acad Sci U S A, 91 (16). pp. 7762-6. ISSN 0027-8424 (Print)

Marcus, S., Polverino, A., Chang, E., Robbins, D., Cobb, M. H., Wigler, M. H. (June 1995) Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe. Proc Natl Acad Sci U S A, 92 (13). pp. 6180-4. ISSN 0027-8424 (Print)

Marcus, S., Polverino, A., Robbins, D., Cobb, M., Wigler, M. H. (April 1994) Conservation of Ste20-Related Protein-Kinases in Eukaryotes. Faseb Journal, 8 (7). A1431-A1431. ISSN 0892-6638

Marcus, S., Wigler, M. H., Xu, H. P., Ballester, R., Kawamukai, M., Polverino, A. (1993) RAS function and protein kinase cascades. Ciba Found Symp, 176. 53-61; discussion 61. ISSN 0300-5208 (Print)

Marshak, D. R., Carroll, D. (1991) Synthetic peptide substrates for casein kinase II. Methods Enzymol, 200. pp. 134-56. ISSN 0076-6879 (Print)0076-6879 (Linking)

Marshak, D. R., Pena, L. A. (1992) Potential role of S100 beta in Alzheimer's disease: an hypothesis involving mitotic protein kinases. Prog Clin Biol Res, 379. pp. 289-307. ISSN 0361-7742 (Print)0361-7742 (Linking)

Marshak, D. R., Russo, G. L. (1994) Regulation of protein kinase CKII during the cell division cycle. Cell Mol Biol Res, 40 (5-6). pp. 513-7. ISSN 0968-8773 (Print)

Marshak, D. R., Russo, G. L., Sutton, A. (April 1994) Mutation of the Casein Kinase-Ii Phosphorylation Site in Cdc28 Causes Premature Entry into S-Phase in the Budding Yeast Saccharomyces-Cerevisiae. Faseb Journal, 8 (7). A1239-A1239. ISSN 0892-6638

Marshak, D. R., Vandenberg, M. T., Bae, Y. S., Yu, I. J. (April 1991) Characterization of synthetic peptide substrates for p34cdc2 protein kinase. J Cell Biochem, 45 (4). pp. 391-400. ISSN 0730-2312 (Print)0730-2312 (Linking)

Mathews, M. B. (August 1993) Viral Evasion of Cellular Defense-Mechanisms - Regulation of the Protein-Kinase Dai by Rna Effectors. Seminars in Virology, 4 (4). pp. 247-257. ISSN 1044-5773

McDermott, U., Sharma, S. V., Dowell, L., Greninger, P., Montagut, C., Lamb, J., Archibald, H., Raudales, R., Tam, A., Lee, D., Rothenberg, S. M., Supko, J. G., Sordella, R., Ulkus, L. E., Iafrate, A. J., Maheswaran, S., Njauw, C. N., Tsao, H., Drew, L., Hanke, J. H., Ma, X. J., Erlander, M. G., Gray, N. S., Haber, D. A., Settleman, J. (December 2007) Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling. Proceedings of the National Academy of Sciences of the United States of America, 104 (50). pp. 19936-41. ISSN 0027-8424

McLeod, M. (July 1989) Regulation of Meiosis - from DNA-Binding Protein to Protein-Kinase. Bioessays, 11 (1). pp. 9-14. ISSN 0265-9247

McVey, D., Ray, S., Gluzman, Y., Berger, L., Wildeman, A. G., Marshak, D. R., Tegtmeyer, P. (September 1993) Cdc2 Phosphorylation of Threonine 124 Activates the Origin-Unwinding Functions of Simian-Virus 40-T Antigen. Journal of Virology, 67 (9). pp. 5206-5215. ISSN 0022-538X

Meijer, L., Arion, D., Golsteyn, R., Pines, J., Brizuela, L., Hunt, T., Beach, D. (August 1989) Cyclin Is a Component of the Sea-Urchin Egg M-Phase Specific Histone H-1 Kinase. Embo Journal, 8 (8). pp. 2275-2282. ISSN 0261-4189

Mellits, K. H., Kostura, M., Mathews, M. B. (June 1990) Interaction of adenovirus VA RNAl with the protein kinase DAI: nonequivalence of binding and function. Cell, 61 (5). pp. 843-52. ISSN 0092-8674 (Print)0092-8674 (Linking)

Minshull, J., Sun, H., Tonks, N. K., Murray, A. W. (November 1994) A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts. Cell, 79 (3). pp. 475-486. ISSN 0092-8674

Mok, J., Kim, P. M., Lam, H. Y. K., Piccirillo, S., Zhou, X., Jeschke, G. R., Sheridan, D. L., Parker, S. A., Desai, V., Jwa, M., Cameroni, E., Niu, H., Good, M., Remenyi, A., Ma, J. L. N., Sheu, Y. J., Sassi, H. E., Sopko, R., Chan, C. S. M., De Virgilio, C., Hollingsworth, N. M., Lim, W. A., Stern, D. F., Stillman, B., Andrews, B. J., Gerstein, M. B., Snyder, M., Turk, B. E. (2010) Deciphering protein kinase specificity through large-scale analysis of yeast phosphorylation site motifs. Science Signaling, 3 (109). ISSN 19450877 (ISSN)

Molz, L., Beach, D. (April 1993) Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity. Embo J, 12 (4). pp. 1723-32. ISSN 0261-4189 (Print)

Mulloy, R., Ferrand, A., Kim, Y., Sordella, R., Bell, D. W., Haber, D. A., Anderson, K. S., Settleman, J. (March 2007) Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib. Cancer Research, 67 (5). pp. 2325-30. ISSN 0008-5472

N

Naguib, Adam, Bencze, Gylua, Cho, Hyejin, Zheng, Wu, Tocilj, Ante, Elkayam, Elad, Faehnle, Christopher R, Jaber, Nadia, Pratt, Christopher, Chen, Muhan, Zong, Wei-Xing, Marks, Michael S, Joshua-Tor, Leemor, Pappin, Darryl J, Trotman, Lloyd C (August 2015) PTEN function is controlled by recruitment to cytoplasmic vesicles. In: AACR 106th Annual Meeting 2015.

Nakaya, N., Hemish, J., Krasnov, P., Kim, S. Y., Stasiv, Y., Michurina, T. V., Herman, D., Davidoff, M. S., Middendorff, R., Enikolopov, G. N. (August 2007) noxin, a novel stress-induced gene involved in cell cycle and apoptosis. Mol Cell Biol, 27 (15). pp. 5430-44. ISSN 0270-7306 (Print)

Neiman, A. M., Stevenson, B. J., Xu, H. P., Sprague, G. F., Herskowitz, I., Wigler, M. H., Marcus, S. (January 1993) Functional homology of protein kinases required for sexual differentiation in Schizosaccharomyces pombe and Saccharomyces cerevisiae suggests a conserved signal transduction module in eukaryotic organisms. Molecular Biology of the Cell, 4 (1). pp. 107-120. ISSN 1059-1524

Nowack, Moritz K., Harashima, Hirofumi, Dissmeyer, Nico, Zhao, Xin'Ai, Bouyer, Daniel, Weimer, Annika K., De Winter, Freya, Yang, Fang, Schnittger, Arp (May 2012) Genetic Framework of Cyclin-Dependent Kinase Function in Arabidopsis. Developmental Cell, 22 (5). pp. 1030-1040. ISSN 1534-5807

O

Osten, P., Hrabetova, S., Sacktor, T. C. (1996) Differential downregulation of protein kinase C isoforms in spreading depression. Neuroscience Letters, 221 (1). pp. 37-40. ISSN 03043940 (ISSN)

Osten, P., Valsamis, L., Harris, A., Sacktor, T. C. (1996) Protein synthesis-dependent formation of protein kinase Mζ in long-term potentiation. Journal of Neuroscience, 16 (8). pp. 2444-2451. ISSN 02706474 (ISSN)

P

Palka, H. L., Park, M., Tonks, N. K. (February 2003) Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1. Journal of Biological Chemistry, 278 (8). pp. 5728-35. ISSN 0021-9258

Pawlak, G., Helfman, D. M. (July 2002) MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway. Journal of Biological Chemistry, 277 (30). pp. 26927-26933. ISSN 0021-9258

Pellicer, A., Wigler, M. H., Axel, R., Silverstein, S. (1978) The transfer and stable integration of HSV thymidine kinase gene into mouse cells. Cell, 14 (1). pp. 133-141. ISSN 0092-8674

Perez, J. L., Khatri, L., Chang, C., Srivastava, S., Osten, P., Ziff, E. B. (2001) PICK1 targets activated protein kinase Cα to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. Journal of Neuroscience, 21 (15). pp. 5417-5428. ISSN 02706474 (ISSN)

Perucho, M., Hanahan, D., Lipsich, L., Wigler, M. H. (May 1980) Isolation of the chicken thymidine kinase gene by plasmid rescue. Nature, 285 (5762). pp. 207-210.

Petersen, M., Brodersen, P., Naested, H., Andreasson, E., Lindhart, U., Johansen, B., Nielsen, H. B., Lacy, M., Austin, M. J., Parker, J. E., Sharma, S. B., Klessig, D. F., Martienssen, R., Mattsson, O., Jensen, A. B., Mundy, J. (December 2000) Arabidopsis MAP kinase 4 negatively regulates systemic acquired resistance. Cell, 103 (7). pp. 1111-1120. ISSN 0092-8674

Polyanskaya, Sofya A (July 2020) A Nuclear Phosphatase-Kinase Signaling Complex That Supports Acute Myeloid Leukemia. PhD thesis, Cold Spring Harbor Laboratory.

Ptashne, M., Gann, A. (February 2003) Imposing specificity on kinases. Science, 299 (5609). pp. 1025-1027. ISSN 0036-8075

Q

Quelle, D. E., Ashmun, R. A., Shurtleff, S. A., Kato, J. Y., Barsagi, D., Roussel, M. F., Sherr, C. J. (August 1993) Overexpression of Mouse D-Type Cyclins Accelerates G(1) Phase in Rodent Fibroblasts. Genes Dev, 7 (8). pp. 1559-1571. ISSN 0890-9369

R

Rajah, Abira, Boudreau, Colton G, Ilie, Alina, Wee, Tse-Luen, Tang, Kaixi, Borisov, Aleksandar Z, Orlowski, John, Brown, Claire M (August 2019) Paxillin S273 Phosphorylation Regulates Adhesion Dynamics and Cell Migration through a Common Protein Complex with PAK1 and βPIX. Scientific Reports, 9 (1). p. 11430. ISSN 2045-2322

Riabowol, K. T., Fink, J. S., Gilman, M. Z., Walsh, D. A., Goodman, R. H., Feramisco, J. R. (November 1988) The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elements. Nature, 336 (6194). pp. 83-6. ISSN 0028-0836

Riabowol, K. T., Gilman, M. Z., Feramisco, J. R. (June 1988) Microinjection of the catalytic subunit of cAMP-dependent protein kinase induces expression of the c-fos gene. Cold Spring Harb Symp Quant Biol, 53 Pt . pp. 85-90. ISSN 1943-4456

Rossomando, A. J., Dent, P., Sturgill, T. W., Marshak, D. R. (March 1994) Mitogen-activated protein kinase kinase 1 (MKK1) is negatively regulated by threonine phosphorylation. Mol Cell Biol, 14 (3). pp. 1594-602. ISSN 0270-7306 (Print)

Roth, S. Y., Collini, M. P., Draetta, G., Beach, D., Allis, C. D. (August 1991) A cdc2-like kinase phosphorylates histone H1 in the amitotic macronucleus of Tetrahymena. EMBO J, 10 (8). pp. 2069-75. ISSN 0261-4189 (Print)0261-4189 (Linking)

Roush, C. L., Kennelly, P. J., Glaccum, M. B., Helfman, D. M., Scott, J. D., Krebs, E. G. (July 1988) Isolation of the Cdna-Encoding Rat Skeletal-Muscle Myosin Light Chain Kinase - Sequence and Tissue Distribution. Journal of Biological Chemistry, 263 (21). pp. 10510-10516. ISSN 0021-9258

Russo, G. L., Vandenberg, M. T., Yu, I. J., Bae, Y. S., Franza, B. R., Marshak, D. R. (October 1992) Casein Kinase-Ii Phosphorylates P34(Cdc2) Kinase in G1 Phase of the Hela-Cell Division Cycle. Journal of Biological Chemistry, 267 (28). pp. 20317-20325. ISSN 0021-9258

S

Sacktor, T. C., Osten, P., Valsamis, H., Jiang, X., Naik, M. U., Sublette, E. (1993) Persistent activation of the ζ isoform of protein kinase C in the maintenance of long-term potentiation. Proceedings of the National Academy of Sciences of the United States of America, 90 (18). pp. 8342-8346. ISSN 00278424 (ISSN)

Safaric Tepes, Polona, Pal, Debjani, Lindsted, Trine, Ibarra, Ingrid, Lujambio, Amaia, Jimenez Sabinina, Vilma, Senturk, Serif, Miller, Madison, Korimerla, Navya, Huang, Jiahao, Glassman, Lawrence, Lee, Paul, Zeltsman, David, Hyman, Kevin, Esposito, Michael, Hannon, Greg, Sordella, Raffaella (July 2021) An epigenetic switch regulates the ontogeny of AXL positive/EGFR-TKI resistant cells by modulating miR-335 expression. eLife, 10. ISSN 2050-084X

Scheffzek, K., Grunewald, P., Wohlgemuth, S., Kabsch, W., Tu, H., Wigler, M. H., Wittinghofer, A., Herrmann, C. (November 2001) The Ras-Byr2RBD complex: Structural basis for Ras effector recognition in yeast. Structure, 9 (11). pp. 1043-1050. ISSN 0969-2126

Schmedt, C., Green, S. R., Manche, L., Taylor, D. R., Ma, Y., Mathews, M. B. (May 1995) Functional characterization of the RNA-binding domain and motif of the double-stranded RNA-dependent protein kinase DAI (PKR). Journal of Molecular Biology, 249 (1). pp. 29-44. ISSN 0022-2836

Schumann, G., Rujescu, D., Kissling, C., Soyka, M., Dahmen, N., Preuss, U. W., Wieman, S., Depner, M., Wellek, S., Lascorz, J., Bondy, B., Giegling, I., Anghelescu, I., Cowen, M. S., Poustka, A., Spanagel, R., Mann, K., Henn, F. A., Szegedi, A. (December 2003) Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts. Biol Psychiatry, 54 (12). pp. 1422-6. ISSN 0006-3223 (Print)0006-3223 (Linking)

Schwertassek, U., Buckley, D. A., Xu, C. F., Lindsay, A. J., McCaffrey, M. W., Neubert, T. A., Tonks, N. K. (June 2010) Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis. Febs Journal, 277 (11). pp. 2463-2473. ISSN 1742-464X

Sheu, Y. J., Kinney, J. B., Stillman, B. (March 2016) Concerted activities of Mcm4, Sld3 and Dbf4 in control of origin activation and DNA replication fork progression. Genome Res, 26 (3). pp. 315-330. ISSN 1549-5469 (Electronic)1088-9051 (Linking) (Public Dataset)

Sheu, Y. J., Stillman, B. (October 2006) Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression. Mol Cell, 24 (1). pp. 101-13. ISSN 1097-2765 (Print)

Sheu, Yi-Jun, Kawaguchi, Risa Karakida, Gillis, Jesse, Stillman, Bruce (May 2021) Prevalent and Dynamic Binding of the Cell Cycle Checkpoint Kinase Rad53 to Gene Promoters. bioRxiv. (Unpublished)

Sheu, Yi-Jun, Kawaguchi, Risa Karakida, Gillis, Jesse, Stillman, Bruce (December 2022) Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters. eLife, 11. e84320. ISSN 2050-084X (Public Dataset)

Shibuya, E. K., Polverino, A. J., Chang, E., Wigler, M. H., Ruderman, J. V. (October 1992) Oncogenic Ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America, 89 (20). pp. 9831-9835. ISSN 0027-8424

Sivertsen, E. A., Galteland, E., Mu, D., Holte, H., Meza-Zepeda, L., Myklebost, O., Patzke, S., Smeland, E. B., Stokke, T. (January 2006) Gain of chromosome 6p is an infrequent cause of increased PIM1 expression in B-cell non-Hodgkin's lymphomas. Leukemia, 20 (3). pp. 539-542. ISSN 08876924

Skoulakis, E. M., Kalderon, D., Davis, R. L. (August 1993) Preferential expression in mushroom bodies of the catalytic subunit of protein kinase A and its role in learning and memory. Neuron, 11 (2). pp. 197-208. ISSN 0896-6273 (Print)

Smolen, G. A., Sordella, R., Muir, B., Mohapatra, G., Barmettler, A., Archibald, H., Kim, W. J., Okimoto, R. A., Bell, D. W., Sgroi, D. C., Christensen, J. G., Settleman, J., Haber, D. A. (February 2006) Amplification of MET may identify a subset of cancers with extreme sensitivity to the selective tyrosine kinase inhibitor PHA-665752. Proceedings of the National Academy of Sciences of the United States of America, 103 (7). pp. 2316-21. ISSN 0027-8424

Sublette, E., Naik, M. U., Jiang, X., Osten, P., Valsamis, H., Osada, S., Ohno, S., Sacktor, T. C. (1993) Evidence for a new, high-molecular weight isoform of protein kinase C in rat hippocampus. Neuroscience Letters, 159 (1-2). pp. 175-178. ISSN 03043940 (ISSN)

Sun, H., Tonks, N. K. (November 1994) The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends in Biochemical Sciences, 19 (11). pp. 480-485. ISSN 0968-0004

T

Tarumoto, Y., Lu, B., Somerville, T. D. D., Huang, Y. H., Milazzo, J. P., Wu, X. S., Klingbeil, O., El Demerdash, O., Shi, J., Vakoc, C. R. (March 2018) LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia. Mol Cell, 69 (6). pp. 1017-1027. ISSN 1097-2765

Taylor, L. K., Marshak, D. R., Landreth, G. E. (January 1993) Identification of a Nerve Growth Factor-Regulated and Epidermal Growth Factor-Regulated Protein-Kinase That Phosphorylates the Protooncogene Product C-Fos. Proc Natl Acad Sci U S A, 90 (2). pp. 368-372. ISSN 0027-8424

The, I., Hannigan, G. E., Cowley, G. S., Reginald, S., Zhong, Y., Gusella, J. F., Hariharan, I. K., Bernards, A. (1997) Rescue of a Drosophila NF1 mutant phenotype by protein kinase A. Science, 276 (5313). pp. 791-794. ISSN 00368075 (ISSN)

Toda, T., Cameron, S., Sass, P., Wigler, M. H. (May 1988) SCH9, a gene of Saccharomyces cerevisiae that encodes a protein distinct from, but functionally and structurally related to, cAMP-dependent protein kinase catalytic subunits. Genes Dev, 2 (5). pp. 517-27. ISSN 0890-9369

Toda, T., Cameron, S., Sass, P., Zoller, M., Scott, J. D., McMullen, B., Hurwitz, M., Krebs, E. G., Wigler, M. H. (April 1987) Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae. Molecular & Cellular Biology, 7 (4). pp. 1371-1377.

Toda, T., Cameron, S., Sass, P., Zoller, M., Wigler, M. H. (1987) Three different genes in Saccharomyces cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase. Cell, 50 (2). pp. 277-288.

Topp, W. C. (1981) Normal Rat-Cell Lines Deficient in Nuclear Thymidine Kinase. Virology, 113 (1). pp. 408-411.

Tournier, Cathy, Davies, Clare C., Harvey, Emma, McMahon, Raymond F. T., Finegan, Katherine G., Connor, Frances, Davis, Roger J., Tuveson, David A. (June 2015) Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Pancreatology, 15 (3, Sup). S36. ISSN 1424-3903

Truong, Thu H, Benner, Elizabeth A, Hagen, Kyla M, Temiz, Nuri A, Kerkvliet, Carlos Perez, Wang, Ying, Cortes-Sanchez, Emilio, Yang, Chieh-Hsiang, Trousdell, Marygrace C, Pengo, Thomas, Guillen, Katrin P, Welm, Bryan E, Dos Santos, Camila O, Telang, Sucheta, Lange, Carol A, Ostrander, Julie H (June 2021) PELP1/SRC-3-dependent regulation of metabolic PFKFB kinases drives therapy resistant ER+ breast cancer. Oncogene. ISSN 0950-9232

Tsien, R. W., Malinow, R. (1990) Long-term potentiation: presynaptic enhancement following postsynaptic activation of Ca(++)-dependent protein kinases. Cold Spring Harb Symp Quant Biol, 55. pp. 147-59. ISSN 0091-7451 (Print)0091-7451 (Linking)

Tu, H., Barr, M., Dong, D. L., Wigler, M. H. (October 1997) Multiple regulatory domains on the Byr2 protein kinase. Mol Cell Biol, 17 (10). pp. 5876-87. ISSN 0270-7306 (Print)

Tu, H., Wigler, M. H. (January 1999) Genetic evidence for Pak1 autoinhibition and its release by Cdc42. Mol Cell Biol, 19 (1). pp. 602-11. ISSN 0270-7306 (Print)

Tyers, M., Futcher, B. (March 1994) Far1 and Fus3 Link the Mating Pheromone Signal-Transduction Pathway to 3 G(1)-Phase Cdc28 Kinase Complexes. Molecular and Cellular Biology, 14 (3). p. 2222. ISSN 0270-7306

Tyers, M., Futcher, B. (September 1993) Far1 and Fus3 Link the Mating Pheromone Signal-Transduction Pathway to 3 G1-Phase Cdc28 Kinase Complexes. Mol Cell Biol, 13 (9). pp. 5659-5669. ISSN 0270-7306

Tyers, M., Tokiwa, G., Nash, R., Futcher, B. (May 1992) The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation. Embo Journal, 11 (5). pp. 1773-1784. ISSN 0261-4189

V

Vancura, A., Carmel, G., Kearney, P., Wang, P. C., Kuret, J. (September 1992) Molecular and Genetic-Analysis of Casein Kinase-I in Yeast. Molecular Biology of the Cell, 3. A337-A337. ISSN 1059-1524

Vancura, A., O'Connor, A., Patterson, S. D., Mirza, U., Chait, B. T., Kuret, J. (August 1993) Isolation and properties of YCK2, a Saccharomyces cerevisiae homolog of casein kinase-1. Arch Biochem Biophys, 305 (1). pp. 47-53. ISSN 0003-9861 (Print)

Vancura, A., Sessler, A., Leichus, B., Kuret, J. (July 1994) A Prenylation Motif Is Required for Plasma-Membrane Localization and Biochemical Function of Casein Kinase-I in Budding Yeast. Journal of Biological Chemistry, 269 (30). pp. 19271-19278. ISSN 0021-9258

Villanueva, A., Lozano, J., Morales, A., Lin, X. H., Deng, X. Z., Hengartner, M. O., Kolesnick, R. N. (September 2001) jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans. Embo Journal, 20 (18). pp. 5114-5128. ISSN 0261-4189

W

Waga, S., Hannon, G. J., Beach, D., Stillman, B. (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature, 369 (6481). pp. 574-578. ISSN 00280836 (ISSN)

Waga, S., Li, R., Stillman, B. (April 1997) p53-induced p21 controls DNA replication. Leukemia, 11 Sup. pp. 321-3. ISSN 0887-6924 (Print)

Walworth, N., Davey, S., Beach, D. (May 1993) Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. Nature, 363 (6427). pp. 368-71. ISSN 0028-0836 (Print)

Wang, H. G., Draetta, G., Moran, E. (August 1991) E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products. Mol Cell Biol, 11 (8). pp. 4253-65. ISSN 0270-7306 (Print)0270-7306 (Linking)

Wang, P. C., Vancura, A., Mitcheson, T. G., Kuret, J. (March 1992) Two genes in Saccharomyces cerevisiae encode a membrane-bound form of casein kinase-1. Mol Biol Cell, 3 (3). pp. 275-86. ISSN 1059-1524 (Print)1059-1524 (Linking)

Wang, S. E., Narasanna, A., Perez-Torres, M., Xiang, B., Wu, F. Y., Yang, S., Carpenter, G., Gazdar, A. F., Muthuswamy, S. K., Arteaga, C. L. (2006) HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell, 10 (1). pp. 25-38. ISSN 15356108

Wang, Y., Xu, H. P., Riggs, M., Rodgers, L., Wigler, M. H. (July 1991) byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype. Molecular & Cellular Biology, 11 (7). pp. 3554-63. ISSN 0270-7306

Wang, Minghui, Gallo, Nicholas B, Tai, Yilin, Li, Bo, Van Aelst, Linda (April 2021) Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex. Neuron. ISSN 0896-6273

Wendel, H. G., Malina, A., Zhao, Z., Zender, L., Kogan, S. C., Cordon-Cardo, C., Pelletier, J., Lowe, S. W. (August 2006) Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. Cancer Res, 66 (15). pp. 7639-46. ISSN 0008-5472 (Print)

Wigler, M. H., Pellicer, A., Silverstein, S., Axel, R. (July 1978) Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor. Cell, 14 (3). pp. 725-731.

Wigler, M. H., Silverstein, S., Lee, L. S., Pellicer, A., Cheng, Y. C., Axel, R. (1977) Transfer of Purified Herpes-Virus Thymidine Kinase Gene to Cultured Mouse Cells. Cell, 11 (1). pp. 223-232. ISSN 0092-8674

X

Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., Beach, D. (1993) p21 is a universal inhibitor of cyclin kinases. Nature, 366 (6456). pp. 701-704. ISSN 00280836 (ISSN)

Xiong, Y., Zhang, H., Beach, D. (October 1992) D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell, 71 (3). pp. 505-14. ISSN 0092-8674 (Print)0092-8674 (Linking)

Xiong, Y., Zhang, H., Beach, D. (August 1993) Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev, 7 (8). pp. 1572-83. ISSN 0890-9369 (Print)

Xu, H. P., White, M., Marcus, S., Wigler, M. H. (January 1994) Concerted action of RAS and G proteins in the sexual response pathways of Schizosaccharomyces pombe. Mol Cell Biol, 14 (1). pp. 50-8. ISSN 0270-7306 (Print)

Xu, M. Z., Chan, S. W., Liu, A. M., Wong, K. F., Fan, S. T., Chen, J., Poon, R. T., Zender, L., Lowe, S. W., Hong, W., Luk, J. M. (March 2011) AXL receptor kinase is a mediator of YAP-dependent oncogenic functions in hepatocellular carcinoma. Oncogene, 30 (10). pp. 1229-1240.

Y

Yang, Yang, Paul, Anirban, Bach, Thao Nguyen, Huang, Z Josh, Zhang, Michael Q (July 2021) Single-cell alternative polyadenylation analysis delineates GABAergic neuron types. BMC Biology, 19 (1). p. 144. ISSN 1741-7007

Yart, A., Roche, S., Wetzker, R., Laffargue, M., Tonks, N., Mayeux, P., Chap, H., Raynal, P. (June 2002) A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid. Journal of Biological Chemistry, 277 (24). pp. 21167-21178. ISSN 0021-9258

Yu, I. J., Spector, D. L., Bae, Y.-S., Marshak, D. R. (September 1991) Immunocytochemical localization of casein kinase II during interphase and mitosis. J Cell Biol, 114 (6). pp. 1217-32. ISSN 0021-9525

Z

Zhang, H., Hannon, G. J., Beach, D. (1994) p21-Containing cyclin kinases exist in both active and inactive states. Genes and Development, 8 (15). pp. 1750-1758. ISSN 08909369 (ISSN)

Zhang, H., Hannon, G. J., Casso, D., Beach, D. (1994) p21 is a component of active cell cycle kinases. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 21-29. ISSN 00917451 (ISSN)

Zhang, H., Kobayashi, R., Galaktionov, K., Beach, D. (September 1995) p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase. Cell, 82 (6). pp. 915-25. ISSN 0092-8674 (Print)

Zhang, H., Xiong, Y., Beach, D. (September 1993) Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Mol Biol Cell, 4 (9). pp. 897-906. ISSN 1059-1524 (Print)

Zhang, Jiali, Wang, Zuo, Zhang, Siwei, Chen, Yanxun, Xiong, Xuexue, Li, Xiaojuan, Tonks, Nicholas K., Fan, Gaofeng (June 2018) Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER. Cellular Signalling, 50. pp. 100-110. ISSN 0898-6568

Zhao, M., Janas, J. A. , Niki, M., Pandolfi, P. P., Van Aelst, L. (April 2006) Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Mol Cell Biol, 26 (7). pp. 2479-89. ISSN 0270-7306 (Print)

Zhong, H., Sia, G.-M., Sato, T. R., Gray, N. W., Mao, T., Khuchua, Z., Huganir, R. L., Svoboda, K. (May 2009) Subcellular Dynamics of Type II PKA in Neurons. Neuron, 62 (3). pp. 363-374.

Zhong, Y. (June 1995) Mediation of PACAP-like neuropeptide transmission by coactivation of Ras/Raf and cAMP signal transduction pathways in Drosophila. Nature, 375 (6532). pp. 588-92. ISSN 0028-0836 (Print)

Zoller, M. J., Yonemoto, W., Taylor, S. S., Johnson, K. E. (March 1991) Mammalian cAMP-dependent protein kinase functionally replaces its homolog in yeast. Gene, 99 (2). pp. 171-9. ISSN 0378-1119 (Print)0378-1119 (Linking)