Items where Community is "Moses lab"

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Number of items at this level: 94.

Paper

Homer, Joshua A, Koelln, Rebecca A, Barrow, Andrew S, Gialelis, Timothy L, Boiarska, Zlata, Steinohrt, Nikita S, Lee, Erinna F, Yang, Wen-Hsuan, Johnson, Robert M, Chung, Taemoon, Habowski, Amber N, Vishwakarma, Dharmendra S, Bhunia, Debmalya, Avanzi, Charlotte, Moorhouse, Adam D, Jackson, Mary, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Fairlie, W Douglas, Haider, Shozeb M, Steinmetz, Michel O, Prota, Andrea E, Moses, John E (March 2024) Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chemical Science, 15 (11). pp. 3879-3892. ISSN 2041-6520 (Public Dataset)

Homer, Joshua A, Sun, Shoujun, Koelln, Rebecca A, Moses, John E (January 2024) Protocol for producing phosphoramidate using phosphorus fluoride exchange click chemistry. STAR Protocols, 5 (1). p. 102824. ISSN 2666-1667

Homer, JA, Xu, L, Kayambu, N, Zheng, Q, Choi, EJ, Kim, BM, Sharpless, KB, Zuilhof, H, Dong, J, Moses, JE (December 2023) Sulfur fluoride exchange. Nature Reviews Methods Primers, 3 (1). ISSN 2662-8449 (In Press)

Sun, S, Homer, JA, Smedley, CJ, Cheng, QQ, Sharpless, KB, Moses, JE (August 2023) Phosphorus fluoride exchange: Multidimensional catalytic click chemistry from phosphorus connective hubs. Chem, 9 (8). pp. 2128-2143. ISSN 2451-9308

Moorhouse, AD, Homer, JA, Moses, JE (August 2023) The certainty of a few good reactions. Chem, 9 (8). pp. 2063-2077. ISSN 2451-9308

Smedley, Christopher J, Giel, Marie‐Claire, Fallon, Thomas, Moses, John E (July 2023) Ethene‐1,1‐disulfonyl Difluoride (EDSF) for SuFEx Click Chemistry: Synthesis of SuFExable 1,1‐Bissulfonylfluoride Substituted Cyclobutene Hubs. Angewandte Chemie International Edition, 135 (30). ISSN 0044-8249

Gialelis, Timothy L, Wang, Zifei, Homer, Joshua A, Yang, Wen-Hsuan, Chung, Taemoon, Hu, Qingting, Smedley, Christopher J, Pawar, Nitin J, Upadhyay, Nitinkumar S, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Moses, John E (April 2023) Inhibition of mitochondrial metabolism by (-)-jerantinine A: synthesis and biological studies in triple-negative breast cancer cells. MedChemComm, 14 (4). pp. 710-714. ISSN 2632-8682

Ottonello, Alessandra, Wyllie, Jessica A, Yahiaoui, Oussama, Sun, Shoujun, Koelln, Rebecca A, Homer, Joshua A, Johnson, Robert M, Murray, Ewan, Williams, Paul, Bolla, Jani R, Robinson, Carol V, Fallon, Thomas, Soares da Costa, Tatiana P, Moses, John E (April 2023) Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria. Proceedings of the National Academy of Sciences of USA, 120 (15). e2208737120. ISSN 0027-8424

Cheng, Yunfei, Li, Gencheng, Smedley, Christopher J, Giel, Marie-Claire, Kitamura, Seiya, Woehl, Jordan L, Bianco, Giulia, Forli, Stefano, Homer, Joshua A, Cappiello, John R, Wolan, Dennis W, Moses, John E, Sharpless, K Barry (September 2022) Diversity oriented clicking delivers β-substituted alkenyl sulfonyl fluorides as covalent human neutrophil elastase inhibitors. Proceedings of the National Academy of Sciences of USA, 119 (37). e2208540119. ISSN 0027-8424

Ottonello, Alessandra, Wyllie, Jessica A, Yahiaoui, Oussama, Murray, Ewan, Williams, Paul, Bolla, Jani R, Robinson, Carol V, Fallon, Thomas, Soares da Costa, Tatiana P, Moses, John E (April 2022) Shapeshifting Antibiotics: Bullvalene Linked Vancomycin Dimers are Effective Against Multidrug-Resistant Gram-Positive Bacteria. ChemRxiv. (Submitted)

Smedley, Christopher J, Homer, Joshua A, Gialelis, Timothy L, Barrow, Andrew S, Koelln, Rebecca A, Moses, John Edward (November 2021) Accelerated SuFEx Click Chemistry For Modular Synthesis. Angewandte Chemie International Edition. ISSN 1433-7851

Li, Suhua, Li, Gencheng, Gao, Bing, Pujari, Sidharam P, Chen, Xiaoyan, Kim, Hyunseok, Zhou, Feng, Klivansky, Liana M, Liu, Yi, Driss, Hafedh, Liang, Dong-Dong, Lu, Jianmei, Wu, Peng, Zuilhof, Han, Moses, John, Sharpless, K Barry (August 2021) SuFExable polymers with helical structures derived from thionyl tetrafluoride. Nature Chemistry. ISSN 1755-4330

Giel, Marie-Claire, Barrow, Andrew S, Smedley, Christopher J, Lewis, William, Moses, John E (June 2021) Aminium cation-radical catalysed selective hydration of (E)-aryl enynes. Chemical Communications. ISSN 1359-7345

Smedley, Christopher, Gialelis, Timothy, Moses, John (2021) Accelerated SuFEx Click Chemistry for Modular Synthesis. chemRxiv. (Submitted)

Smedley, C. J., Li, G., Barrow, A. S., Gialelis, T. L., Giel, M. C., Ottonello, A., Cheng, Y., Kitamura, S., Wolan, D. W., Sharpless, K. B., Moses, J. E. (April 2020) Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs. Angew Chem Int Ed Engl. ISSN 1433-7851

Giel, M. C., Smedley, C. J., Mackie, E. R. R., Guo, T., Dong, J., Soares da Costa, T. P., Moses, J. E. (January 2020) Metal-Free Synthesis of Functional 1-Substituted-1,2,3-Triazoles from Ethenesulfonyl Fluoride and Organic Azides. Angew Chem Int Ed Engl, 59 (3). pp. 1181-1186. ISSN 1433-7851

Suhua, Li, Gencheng, Li, Bing, Gao, Sidharam P., Pujari, Xiaoyan, Chen, Hyunseok, Kim, Feng, Zhou, Liana M., Klivansky, Yi, Liu, Hafedh, Driss, Rachael E., Impey, Tatiana P. Soares da, Costa, Jianmei, Lu, Peng, Wu, Han, Zuilhof, John E., Moses, K. Barry, Sharpless (October 2019) SuFExable Polymers with Helical Structures Derived from Thionyl Tetrafluoride (SOF4). chemRxiv. (Unpublished)

Zheng, Q., Woehl, J. L., Kitamura, S., Santos-Martins, D., Smedley, C. J., Li, G., Forli, S., Moses, J. E., Wolan, D. W., Sharpless, K. B. (September 2019) SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proc Natl Acad Sci U S A, 116 (38). pp. 18808-18814. ISSN 0027-8424 (Print)0027-8424

Barrow, A. S., Smedley, C. J., Zheng, Q., Li, S., Dong, J., Moses, J. E. (August 2019) The growing applications of SuFEx click chemistry. Chem Soc Rev, 48 (17). pp. 4731-4758. ISSN 0306-0012

Liu, F., Wang, H., Li, S., Bare, G. A. L., Chen, X., Wang, C., Moses, J. E., Wu, P., Sharpless, K. B. (June 2019) Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF(4) )-Derived Connective Hubs for Bioconjugation to DNA and Proteins. Angew Chem Int Ed Engl, 58 (24). pp. 8029-8033. ISSN 1433-7851 (Print)1433-7851

Smedley, C. J., Zheng, Q., Gao, B., Li, S., Molino, A., Duivenvoorden, H. M., Parker, B. S., Wilson, D. J. D., Sharpless, K. B., Moses, J. E. (March 2019) Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angew Chem Int Ed Engl, 58 (14). pp. 4552-4556. ISSN 1433-7851

Smedley, Christopher J, Zheng, Qinheng, Gao, Bing, Li, Suhua, Molino, Andrew, Duivenvoorden, Hendrika M, Parker, Belinda S, Wilson, David JD, Sharpless, K Barry, Moses, John E (March 2019) Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angewandte Chemie International Edition, 131 (14). pp. 4600-4604. ISSN 0044-8249

Qinheng, Zheng, Jordan L., Woehl, Seiya, Kitamura, Diogo, Santos-Martins, Christopher J., Smedley, Gencheng, Li, Stefano, Forli, John E., Moses, Dennis W., Wolan, K. Barry, Sharpless (March 2019) "Sleeping Beauty" Phenomenon: SuFEx-Enabled Discovery of Selective Covalent Inhibitors of Human Neutrophil Elastase. ChemRxiv. (Unpublished)

Giel, Marie-Claire, Smedley, Christopher, Mackie, Emily, Guo, Taijie, Dong, Jiajia, Costa, Tatiana Soares da, Moses, John (2019) Metal-Free Click Synthesis of Functional 1-Substituted-1,2,3-Triazoles. (Submitted)

Smedley, Christopher, Gao, Bing, Li, Suhua, Zheng, Qinheng, Molino, Andrew, Duivenvoorden, Hendrika, Parker, Belinda, Wilson, David, Sharpless, Barry, Moses, John (December 2018) Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. ChemRxiv. (Unpublished)

Smedley, Christopher J, Gao, Bing, Li, Suhua, Zheng, Qinheng, Molino, Andrew, Duivenvoorden, Hendrika M, Parker, Belinda S, Wilson, David JD, Sharpless, K Barry, Moses, John E (November 2018) Bifluoride Ion Catalyzed Late-Stage SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. (Submitted)

Randall, J. D., Eyckens, D. J., Stojcevski, F., Francis, P. S., Doeven, E. H., Barlow, A. J., Barrow, A. S., Arnold, C. L., Moses, J. E., Henderson, L. C. (September 2018) Modification of Carbon Fibre Surfaces by Sulfur-Fluoride Exchange Click Chemistry. Chemphyschem. ISSN 1439-4235

Gahtory, D., Sen, R., Pujari, S., Li, S., Zheng, Q., Moses, J. E., Sharpless, K. B., Zuilhof, H. (July 2018) Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms. Chemistry, 24 (41). pp. 10550-10556. ISSN 0947-6539 (Print)0947-6539

Sharma, P., Bhat, S. V., Prabhath, M. R. R., Molino, A., Nauha, E., Wilson, D. J. D., Moses, J. E. (July 2018) Synthesis of 1,2,4-Triazol-3-imines via Selective Stepwise Cycloaddition of Nitrile Imines with Organo-cyanamides. Org Lett, 20 (14). pp. 4263-4266. ISSN 1523-7052

Smedley, C. J., Stanley, P. A., Qazzaz, M. E., Prota, A. E., Olieric, N., Collins, H., Eastman, H., Barrow, A. S., Lim, K. H., Kam, T. S., Smith, B. J., Duivenvoorden, H. M., Parker, B. S., Bradshaw, T. D., Steinmetz, M. O., Moses, J. E. (July 2018) Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site. Sci Rep, 8 (1). p. 10617. ISSN 2045-2322

Smedley, C. J., Giel, M. C., Molino, A., Barrow, A. S., Wilson, D. J. D., Moses, J. E. (June 2018) 1-Bromoethene-1-sulfonyl fluoride (BESF) is another good connective hub for SuFEx click chemistry. Chem Commun (Camb), 54 (47). pp. 6020-6023. ISSN 1359-7345

Powell, Kimberley J., Richens, Joanna L., Bramble, Jonathan P., Han, Li-Chen, Sharma, Pallavi, O'Shea, Paul, Moses, John E. (March 2018) Photochemical activity of membrane-localised polyketide derived marine natural products. Tetrahedron, 74 (12). pp. 1191-1198. ISSN 0040-4020

Jenner, M., Kosol, S., Griffiths, D., Prasongpholchai, P., Manzi, L., Barrow, A. S., Moses, J. E., Oldham, N. J., Lewandowski, J. R., Challis, G. L. (March 2018) Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases. Nat Chem Biol, 14 (3). pp. 270-275. ISSN 1552-4450 (Print)1552-4450

Gao, B., Li, S., Wu, P., Moses, J. E., Sharpless, K. B. (February 2018) SuFEx Chemistry of Thionyl Tetrafluoride (SOF(4) ) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates. Angew Chem Int Ed Engl, 57 (7). pp. 1939-1943. ISSN 1433-7851 (Print)1433-7851

Manzi, L., Barrow, A. S., Hopper, J. T. S., Kaminska, R., Kleanthous, C., Robinson, C. V., Moses, J. E., Oldham, N. J. (November 2017) Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein. Angew Chem Int Ed Engl, 56 (47). pp. 14873-14877. ISSN 1433-7851

Manzi, Lucio, Barrow, Andrew S, Hopper, Jonathan TS, Kaminska, Renata, Kleanthous, Colin, Robinson, Carol V, Moses, John E, Oldham, Neil J (November 2017) Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane‐Spanning Protein. Angewandte Chemie International Edition, 129 (47). pp. 15069-15073. ISSN 0044-8249

Smedley, C. J., Barrow, A. S., Spiteri, C., Giel, M. C., Sharma, P., Moses, J. E. (July 2017) Sulfur-Fluoride Exchange (SuFEx)-Mediated Synthesis of Sterically Hindered and Electron-Deficient Secondary and Tertiary Amides via Acyl Fluoride Intermediates. Chemistry, 23 (42). pp. 9990-9995. ISSN 0947-6539

Li, S., Wu, P., Moses, J. E., Sharpless, K. B. (March 2017) Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF(4) Hub. Angew Chem Int Ed Engl, 56 (11). pp. 2903-2908. ISSN 1433-7851 (Print)1433-7851

Silverman, S. M., Moses, J. E., Sharpless, K. B. (January 2017) Reengineering Antibiotics to Combat Bacterial Resistance: Click Chemistry [1,2,3]-Triazole Vancomycin Dimers with Potent Activity against MRSA and VRE. Chemistry, 23 (1). pp. 79-83. ISSN 0947-6539

Moses, John E, Moorhouse, Adam D (December 2016) Correction: The growing applications of click chemistry. Chemical Society Reviews, 45 (24). p. 6888. ISSN 0306-0012

Manzi, L., Barrow, A. S., Scott, D., Layfield, R., Wright, T. G., Moses, J. E., Oldham, N. J. (November 2016) Carbene footprinting accurately maps binding sites in protein-ligand and protein-protein interactions. Nat Commun, 7. p. 13288. ISSN 2041-1723

Han, L. C., Stanley, P. A., Wood, P. J., Sharma, P., Kuruppu, A. I., Bradshaw, T. D., Moses, J. E. (August 2016) Horner-Wadsworth-Emmons approach to piperlongumine analogues with potent anti-cancer activity. Org Biomol Chem, 14 (31). pp. 7585-93. ISSN 1477-0520

Zhang, E., Tang, J., Li, S., Wu, P., Moses, J. E., Sharpless, K. B. (April 2016) Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates. Chemistry, 22 (16). pp. 5692-7. ISSN 0947-6539 (Print)0947-6539

Bhat, S. V., Robinson, D., Moses, J. E., Sharma, P. (March 2016) Synthesis of Oxadiazol-5-imines via the Cyclizative Capture of in Situ Generated Cyanamide Ions and Nitrile Oxides. Org Lett, 18 (5). pp. 1100-3. ISSN 1523-7052

Roe, S., Gunaratnam, M., Spiteri, C., Sharma, P., Alharthy, R. D., Neidle, S., Moses, J. E. (August 2015) Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors. Org Biomol Chem, 13 (31). pp. 8500-4. ISSN 1477-0520

Moore, J. C., Davies, E. S., Walsh, D. A., Sharma, P., Moses, J. E. (October 2014) Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels-Alder reaction.