Items where Community is "Moses lab"

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Smedley, C. J., Li, G., Barrow, A. S., Gialelis, T. L., Giel, M. C., Ottonello, A., Cheng, Y., Kitamura, S., Wolan, D. W., Sharpless, K. B., Moses, J. E. (April 2020) Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2-Substituted-Alkynyl-1-Sulfonyl Fluoride (SASF) Hubs. Angew Chem Int Ed Engl. ISSN 1433-7851

Giel, M. C., Smedley, C. J., Mackie, E. R. R., Guo, T., Dong, J., Soares da Costa, T. P., Moses, J. E. (January 2020) Metal-Free Synthesis of Functional 1-Substituted-1,2,3-Triazoles from Ethenesulfonyl Fluoride and Organic Azides. Angew Chem Int Ed Engl, 59 (3). pp. 1181-1186. ISSN 1433-7851

Suhua, Li, Gencheng, Li, Bing, Gao, Sidharam P., Pujari, Xiaoyan, Chen, Hyunseok, Kim, Feng, Zhou, Liana M., Klivansky, Yi, Liu, Hafedh, Driss, Rachael E., Impey, Tatiana P. Soares da, Costa, Jianmei, Lu, Peng, Wu, Han, Zuilhof, John E., Moses, K. Barry, Sharpless (October 2019) SuFExable Polymers with Helical Structures Derived from Thionyl Tetrafluoride (SOF4). chemRxiv. (Unpublished)

Zheng, Q., Woehl, J. L., Kitamura, S., Santos-Martins, D., Smedley, C. J., Li, G., Forli, S., Moses, J. E., Wolan, D. W., Sharpless, K. B. (September 2019) SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase. Proc Natl Acad Sci U S A, 116 (38). pp. 18808-18814. ISSN 0027-8424 (Print)0027-8424

Barrow, A. S., Smedley, C. J., Zheng, Q., Li, S., Dong, J., Moses, J. E. (August 2019) The growing applications of SuFEx click chemistry. Chem Soc Rev, 48 (17). pp. 4731-4758. ISSN 0306-0012

Liu, F., Wang, H., Li, S., Bare, G. A. L., Chen, X., Wang, C., Moses, J. E., Wu, P., Sharpless, K. B. (June 2019) Biocompatible SuFEx Click Chemistry: Thionyl Tetrafluoride (SOF(4) )-Derived Connective Hubs for Bioconjugation to DNA and Proteins. Angew Chem Int Ed Engl, 58 (24). pp. 8029-8033. ISSN 1433-7851 (Print)1433-7851

Smedley, C. J., Zheng, Q., Gao, B., Li, S., Molino, A., Duivenvoorden, H. M., Parker, B. S., Wilson, D. J. D., Sharpless, K. B., Moses, J. E. (March 2019) Bifluoride Ion Mediated SuFEx Trifluoromethylation of Sulfonyl Fluorides and Iminosulfur Oxydifluorides. Angew Chem Int Ed Engl, 58 (14). pp. 4552-4556. ISSN 1433-7851

Randall, J. D., Eyckens, D. J., Stojcevski, F., Francis, P. S., Doeven, E. H., Barlow, A. J., Barrow, A. S., Arnold, C. L., Moses, J. E., Henderson, L. C. (September 2018) Modification of Carbon Fibre Surfaces by Sulfur-Fluoride Exchange Click Chemistry. Chemphyschem. ISSN 1439-4235

Gahtory, D., Sen, R., Pujari, S., Li, S., Zheng, Q., Moses, J. E., Sharpless, K. B., Zuilhof, H. (July 2018) Quantitative and Orthogonal Formation and Reactivity of SuFEx Platforms. Chemistry, 24 (41). pp. 10550-10556. ISSN 0947-6539 (Print)0947-6539

Sharma, P., Bhat, S. V., Prabhath, M. R. R., Molino, A., Nauha, E., Wilson, D. J. D., Moses, J. E. (July 2018) Synthesis of 1,2,4-Triazol-3-imines via Selective Stepwise Cycloaddition of Nitrile Imines with Organo-cyanamides. Org Lett, 20 (14). pp. 4263-4266. ISSN 1523-7052

Smedley, C. J., Stanley, P. A., Qazzaz, M. E., Prota, A. E., Olieric, N., Collins, H., Eastman, H., Barrow, A. S., Lim, K. H., Kam, T. S., Smith, B. J., Duivenvoorden, H. M., Parker, B. S., Bradshaw, T. D., Steinmetz, M. O., Moses, J. E. (July 2018) Sustainable Syntheses of (-)-Jerantinines A & E and Structural Characterisation of the Jerantinine-Tubulin Complex at the Colchicine Binding Site. Sci Rep, 8 (1). p. 10617. ISSN 2045-2322

Smedley, C. J., Giel, M. C., Molino, A., Barrow, A. S., Wilson, D. J. D., Moses, J. E. (June 2018) 1-Bromoethene-1-sulfonyl fluoride (BESF) is another good connective hub for SuFEx click chemistry. Chem Commun (Camb), 54 (47). pp. 6020-6023. ISSN 1359-7345

Powell, Kimberley J., Richens, Joanna L., Bramble, Jonathan P., Han, Li-Chen, Sharma, Pallavi, O'Shea, Paul, Moses, John E. (March 2018) Photochemical activity of membrane-localised polyketide derived marine natural products. Tetrahedron, 74 (12). pp. 1191-1198. ISSN 0040-4020

Jenner, M., Kosol, S., Griffiths, D., Prasongpholchai, P., Manzi, L., Barrow, A. S., Moses, J. E., Oldham, N. J., Lewandowski, J. R., Challis, G. L. (March 2018) Mechanism of intersubunit ketosynthase-dehydratase interaction in polyketide synthases. Nat Chem Biol, 14 (3). pp. 270-275. ISSN 1552-4450 (Print)1552-4450

Gao, B., Li, S., Wu, P., Moses, J. E., Sharpless, K. B. (February 2018) SuFEx Chemistry of Thionyl Tetrafluoride (SOF(4) ) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates. Angew Chem Int Ed Engl, 57 (7). pp. 1939-1943. ISSN 1433-7851 (Print)1433-7851

Manzi, L., Barrow, A. S., Hopper, J. T. S., Kaminska, R., Kleanthous, C., Robinson, C. V., Moses, J. E., Oldham, N. J. (November 2017) Carbene Footprinting Reveals Binding Interfaces of a Multimeric Membrane-Spanning Protein. Angew Chem Int Ed Engl, 56 (47). pp. 14873-14877. ISSN 1433-7851

Smedley, C. J., Barrow, A. S., Spiteri, C., Giel, M. C., Sharma, P., Moses, J. E. (July 2017) Sulfur-Fluoride Exchange (SuFEx)-Mediated Synthesis of Sterically Hindered and Electron-Deficient Secondary and Tertiary Amides via Acyl Fluoride Intermediates. Chemistry, 23 (42). pp. 9990-9995. ISSN 0947-6539

Li, S., Wu, P., Moses, J. E., Sharpless, K. B. (March 2017) Multidimensional SuFEx Click Chemistry: Sequential Sulfur(VI) Fluoride Exchange Connections of Diverse Modules Launched From An SOF(4) Hub. Angew Chem Int Ed Engl, 56 (11). pp. 2903-2908. ISSN 1433-7851 (Print)1433-7851

Silverman, S. M., Moses, J. E., Sharpless, K. B. (January 2017) Reengineering Antibiotics to Combat Bacterial Resistance: Click Chemistry [1,2,3]-Triazole Vancomycin Dimers with Potent Activity against MRSA and VRE. Chemistry, 23 (1). pp. 79-83. ISSN 0947-6539

Manzi, L., Barrow, A. S., Scott, D., Layfield, R., Wright, T. G., Moses, J. E., Oldham, N. J. (November 2016) Carbene footprinting accurately maps binding sites in protein-ligand and protein-protein interactions. Nat Commun, 7. p. 13288. ISSN 2041-1723

Han, L. C., Stanley, P. A., Wood, P. J., Sharma, P., Kuruppu, A. I., Bradshaw, T. D., Moses, J. E. (August 2016) Horner-Wadsworth-Emmons approach to piperlongumine analogues with potent anti-cancer activity. Org Biomol Chem, 14 (31). pp. 7585-93. ISSN 1477-0520

Zhang, E., Tang, J., Li, S., Wu, P., Moses, J. E., Sharpless, K. B. (April 2016) Chemoselective Synthesis of Polysubstituted Pyridines from Heteroaryl Fluorosulfates. Chemistry, 22 (16). pp. 5692-7. ISSN 0947-6539 (Print)0947-6539

Bhat, S. V., Robinson, D., Moses, J. E., Sharma, P. (March 2016) Synthesis of Oxadiazol-5-imines via the Cyclizative Capture of in Situ Generated Cyanamide Ions and Nitrile Oxides. Org Lett, 18 (5). pp. 1100-3. ISSN 1523-7052

Roe, S., Gunaratnam, M., Spiteri, C., Sharma, P., Alharthy, R. D., Neidle, S., Moses, J. E. (August 2015) Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors. Org Biomol Chem, 13 (31). pp. 8500-4. ISSN 1477-0520

Moore, J. C., Davies, E. S., Walsh, D. A., Sharma, P., Moses, J. E. (October 2014) Formal synthesis of kingianin A based upon a novel electrochemically-induced radical cation Diels-Alder reaction. Chem Commun (Camb), 50 (83). pp. 12523-5. ISSN 1359-7345

Dempster, S., Harper, S., Moses, J. E., Dreveny, I. (May 2014) Structural characterization of the apo form and NADH binary complex of human lactate dehydrogenase. Acta Crystallogr D Biol Crystallogr, 70 (Pt 5). pp. 1484-90. ISSN 0907-4449 (Print)0907-4449

Powell, K. J., Han, L. C., Sharma, P., Moses, J. E. (April 2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Org Lett, 16 (8). pp. 2158-61. ISSN 1523-7052

Carbone, G., Burnley, J., Moses, J. E. (April 2013) A catalytic and tert-butoxide ion-mediated amidation of aldehydes with para-nitro azides. Chem Commun (Camb), 49 (27). pp. 2759-61. ISSN 1359-7345

Sharma, P., Ritson, D. J., Burnley, J., Moses, J. E. (October 2011) A synthetic approach to kingianin A based on biosynthetic speculation. Chem Commun (Camb), 47 (38). pp. 10605-7. ISSN 1359-7345

Ritson, D. J., Spiteri, C., Moses, J. E. (May 2011) A silver-mediated one-step synthesis of oxazoles. J Org Chem, 76 (9). pp. 3519-22. ISSN 0022-3263

Moorhouse, A. D., Spiteri, C., Sharma, P., Zloh, M., Moses, J. E. (January 2011) Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5. Chem Commun (Camb), 47 (1). pp. 230-2. ISSN 1359-7345

Lombardo, C. M., Martínez, I. S., Haider, S., Gabelica, V., De Pauw, E., Moses, J. E., Neidle, S. (December 2010) Structure-based design of selective high-affinity telomeric quadruplex-binding ligands. Chem Commun (Camb), 46 (48). pp. 9116-8. ISSN 1359-7345

Spiteri, C., Keeling, S., Moses, J. E. (August 2010) New synthesis of 1-substituted-1H-indazoles via 1,3-dipolar cycloaddition of in situ generated nitrile imines and benzyne. Org Lett, 12 (15). pp. 3368-71. ISSN 1523-7052

Roe, S., Ritson, D. J., Garner, T., Searle, M., Moses, J. E. (June 2010) Tuneable DNA-based asymmetric catalysis using a G-quadruplex supramolecular assembly. Chem Commun (Camb), 46 (24). pp. 4309-11. ISSN 1359-7345

Sharma, P., Moses, J. E. (June 2010) Ethynyldiisopropylsilyl: a new alkynylsilane protecting group and "click" linker. Org Lett, 12 (12). pp. 2860-3. ISSN 1523-7052

Spiteri, C., Mason, C., Zhang, F., Ritson, D. J., Sharma, P., Keeling, S., Moses, J. E. (June 2010) An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne. Org Biomol Chem, 8 (11). pp. 2537-42. ISSN 1477-0520

Sharma, P., Moses, J. E. (March 2010) Photochemical Studies of the Tridachiahydropyrones in Seawater. Synlett (4). pp. 525-528. ISSN 0936-5214

Garner, T. P., Williams, H. E., Gluszyk, K. I., Roe, S., Oldham, N. J., Stevens, M. F., Moses, J. E., Searle, M. S. (October 2009) Selectivity of small molecule ligands for parallel and anti-parallel DNA G-quadruplex structures. Org Biomol Chem, 7 (20). pp. 4194-200. ISSN 1477-0520

Moses, John E., Rueping, Magnus, Cronin, Leroy (September 2009) Highlights from the 44th EUCHEM Conference on Stereochemistry, Bürgenstock, Switzerland, May 2009. Chemical Communications (41). pp. 6125-6128. ISSN 1359-7345

Gunaratnam, M., Green, C., Moreira, J. B., Moorhouse, A. D., Kelland, L. R., Moses, J. E., Neidle, S. (July 2009) G-quadruplex compounds and cis-platin act synergistically to inhibit cancer cell growth in vitro and in vivo. Biochem Pharmacol, 78 (2). pp. 115-22. ISSN 0006-2952

Sharma, P., Lygo, B., Lewis, W., Moses, J. E. (April 2009) Biomimetic synthesis and structural reassignment of the tridachiahydropyrones. J Am Chem Soc, 131 (16). pp. 5966-72. ISSN 0002-7863

Zhang, F., Moses, J. E. (April 2009) Benzyne click chemistry with in situ generated aromatic azides. Org Lett, 11 (7). pp. 1587-90. ISSN 1523-7052

Sharma, P., Griffiths, N., Moses, J. E. (September 2008) Biomimetic synthesis and structural revision of (+/-)-tridachiahydropyrone. Org Lett, 10 (18). pp. 4025-7. ISSN 1523-7052

Moorhouse, A. D., Moses, J. E. (August 2008) Microwave enhancement of a 'one-pot' tandem azidation-'click' cycloaddition of anilines. Synlett (14). pp. 2089-2092. ISSN 0936-5214

Eade, S. J., Walter, M. W., Byrne, C., Odell, B., Rodriguez, R., Baldwin, J. E., Adlington, R. M., Moses, J. E. (July 2008) Biomimetic synthesis of pyrone-derived natural products: exploring chemical pathways from a unique polyketide precursor. J Org Chem, 73 (13). pp. 4830-9. ISSN 0022-3263

Moorhouse, A. D., Haider, S., Gunaratnam, M., Munnur, D., Neidle, S., Moses, J. E. (June 2008) Targeting telomerase and telomeres: a click chemistry approach towards highly selective G-quadruplex ligands. Mol Biosyst, 4 (6). pp. 629-42. ISSN 1742-2051

Moorhouse, A. D., Moses, J. E. (May 2008) Click chemistry and medicinal chemistry: a case of "cyclo-addiction". ChemMedChem, 3 (5). pp. 715-23. ISSN 1860-7179

Barral, K., Moorhouse, A. D., Moses, J. E. (April 2007) Efficient conversion of aromatic amines into azides: a one-pot synthesis of triazole linkages. Org Lett, 9 (9). pp. 1809-11. ISSN 1523-7060 (Print)1523-7052

Moorhouse, A. D., Santos, A. M., Gunaratnam, M., Moore, M., Neidle, S., Moses, J. E. (December 2006) Stabilization of G-quadruplex DNA by highly selective ligands via click chemistry. J Am Chem Soc, 128 (50). pp. 15972-3. ISSN 0002-7863 (Print)0002-7863

Rodriguez, R., Moses, J. E., Adlington, R. M., Baldwin, J. E. (October 2005) A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of the benzopyran derived natural products (+/-)-lucidene and (+/-)-alboatrin. Org Biomol Chem, 3 (19). pp. 3488-95. ISSN 1477-0520 (Print)1477-0520

Jacobsen, M. F., Moses, J. E., Adlington, R. M., Baldwin, J. E. (June 2005) The total synthesis of spectinabilin and its biomimetic conversion to SNF4435C and SNF4435D. Org Lett, 7 (12). pp. 2473-6. ISSN 1523-7060 (Print)1523-7052

Moses, J. E., Adlington, R. M., Rodriguez, R., Eade, S. J., Baldwin, J. E. (April 2005) Biomimetic synthesis of (+/-)-9,10-deoxytridachione. Chem Commun (Camb) (13). pp. 1687-9. ISSN 1359-7345 (Print)1359-7345

Jacobsen, M. F., Moses, J. E., Adlington, R. M., Baldwin, J. E. (February 2005) A short total synthesis of aureothin and N-acetylaureothamine. Org Lett, 7 (4). pp. 641-4. ISSN 1523-7060 (Print)1523-7052

Rodriguez, R., Adlington, R. M., Moses, J. E., Cowley, A., Baldwin, J. E. (September 2004) A new and efficient method for o-quinone methide intermediate generation: application to the biomimetic synthesis of (+/-)-Alboatrin. Org Lett, 6 (20). pp. 3617-9. ISSN 1523-7060 (Print)1523-7052

Moses, J. E., Commeiras, L., Baldwin, J. E., Adlington, R. M. (August 2003) Total synthesis of panepophenanthrin. Org Lett, 5 (17). pp. 2987-8. ISSN 1523-7060 (Print)1523-7052

Moses, J. E., Baldwin, J. E., Marquez, R., Adlington, R. M., Claridge, T. D., Odell, B. (March 2003) Biomimetic synthesis of the crispatene core. Org Lett, 5 (5). pp. 661-3. ISSN 1523-7060 (Print)1523-7052

Moses, J. E., Baldwin, J. E., Marquez, R., Adlington, R. M., Cowley, A. R. (October 2002) Studies on the biomimetic synthesis of SNF4435 C and D. Org Lett, 4 (21). pp. 3731-4. ISSN 1523-7060 (Print)1523-7052

Conference or Workshop Item

Abdullah, Nurul Akmaryanti, Moses, John, Han, Li Chen, Storr, Sarah, Ammar, Aula, Martin, Stewart G. (July 2017) Abstract 5210: Differential cytotoxic effects of Piperlongumine analogues and their radiotherapeutic response in breast cancer. In: UNSPECIFIED.

Book

Qinheng, Zheng, Jordan L., Woehl, Seiya, Kitamura, Diogo, Santos-Martins, Christopher J., Smedley, Gencheng, Li, Stefano, Forli, John E., Moses, Dennis W., Wolan, K. Barry, Sharpless (March 2019) "Sleeping Beauty" Phenomenon: SuFEx-Enabled Discovery of Selective Covalent Inhibitors of Human Neutrophil Elastase. UNSPECIFIED. (Unpublished)

This list was generated on Thu May 6 09:20:24 2021 EDT.
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