Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5

Moorhouse, A. D., Spiteri, C., Sharma, P., Zloh, M., Moses, J. E. (January 2011) Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5. Chem Commun (Camb), 47 (1). pp. 230-2. ISSN 1359-7345

URL: https://pubmed.ncbi.nlm.nih.gov/20676418/

DOI: 10.1039/c0cc01166e

Abstract

hLDH-5 has emerged as a promising target for anti-glycolytic cancer chemotherapy. Here we report a first generation of bifunctional inhibitors, which show promising activity against hLDH-5.

Item Type:	Paper
Additional Information:	1364-548x Moorhouse, Adam D Spiteri, Christian Sharma, Pallavi Zloh, Mire Moses, John E Journal Article Research Support, Non-U.S. Gov't England Chem Commun (Camb). 2011 Jan 7;47(1):230-2. doi: 10.1039/c0cc01166e. Epub 2010 Jul 30.
CSHL Authors:	Moses, John E.
Communities:	CSHL labs > Moses lab
Depositing User:	Matthew Dunn
Date:	7 January 2011
Date Deposited:	08 Jan 2021 18:37
Last Modified:	08 Jan 2021 18:37
URI:	https://repository.cshl.edu/id/eprint/39547

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