Chemoselective palladium-catalyzed cyanation of alkenyl halides

Powell, K. J., Han, L. C., Sharma, P., Moses, J. E. (April 2014) Chemoselective palladium-catalyzed cyanation of alkenyl halides. Org Lett, 16 (8). pp. 2158-61. ISSN 1523-7052

DOI: 10.1021/ol500618w


A palladium-catalyzed cyanation of alkenyl halides using acetone cyanohydrin is described. A number of structurally diverse alkenylic nitrile containing compounds was prepared in one step under optimized conditions. The reaction proved to be efficient, chemoselective, easy to perform, and tolerant of a number of functional groups.

Item Type: Paper
Additional Information: 1523-7052 Powell, Kimberley J Han, Li-Chen Sharma, Pallavi Moses, John E Journal Article Research Support, Non-U.S. Gov't United States Org Lett. 2014 Apr 18;16(8):2158-61. doi: 10.1021/ol500618w. Epub 2014 Mar 27.
CSHL Authors:
Communities: CSHL labs > Moses lab
Depositing User: Matthew Dunn
Date: 18 April 2014
Date Deposited: 08 Jan 2021 18:21
Last Modified: 08 Jan 2021 18:21

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