SuFExable polymers with helical structures derived from thionyl tetrafluoride

Li, Suhua, Li, Gencheng, Gao, Bing, Pujari, Sidharam P, Chen, Xiaoyan, Kim, Hyunseok, Zhou, Feng, Klivansky, Liana M, Liu, Yi, Driss, Hafedh, Liang, Dong-Dong, Lu, Jianmei, Wu, Peng, Zuilhof, Han, Moses, John, Sharpless, K Barry (August 2021) SuFExable polymers with helical structures derived from thionyl tetrafluoride. Nature Chemistry. ISSN 1755-4330

DOI: 10.1038/s41557-021-00726-x


Sulfur(VI) fluoride exchange (SuFEx) is a category of click chemistry that enables covalent linking of modular units through sulfur(VI) connective hubs. The efficiency of SuFEx and the stability of the resulting bonds have led to polymer chemistry applications. Now, we report the SuFEx click chemistry synthesis of several structurally diverse SOF4-derived copolymers based on the polymerization of bis(iminosulfur oxydifluorides) and bis(aryl silyl ethers). This polymer class presents two key characteristics. First, the [-N=S(=O)F-O-] polymer backbone linkages are themselves SuFExable and undergo precise SuFEx-based post-modification with phenols or amines to yield branched functional polymers. Second, studies of individual polymer chains of several of these new materials indicate helical polymer structures. The robust nature of SuFEx click chemistry offers the potential for post-polymerization modification, enabling the synthesis of materials with control over composition and conformation.

Item Type: Paper
Subjects: chemistry > chemical synthesis
chemistry > techniques > click chemistry
chemistry > techniques
CSHL Authors:
Communities: CSHL labs > Moses lab
CSHL Cancer Center Program
CSHL Cancer Center Program > Gene Regulation and Inheritance Program
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: 16 August 2021
Date Deposited: 18 Aug 2021 13:26
Last Modified: 13 Feb 2024 18:43
PMCID: PMC8713280

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