Items where Community is "Cellular Communication in Cancer Program"

Paper

Tuveson, David, Allen, Peter (November 2024) The evolving role for surgery in pancreatic cancer. Carcinogenesis. ISSN 0143-3334

Swamynathan, Manojit M, Kuang, Shan, Watrud, Kaitlin E, Doherty, Mary R, Gineste, Charlotte, Mathew, Grinu, Gong, Grace Q, Cox, Hilary, Cheng, Eileen, Reiss, David, Kendall, Jude, Ghosh, Diya, Reczek, Colleen R, Zhao, Xiang, Herzka, Tali, Špokaitė, Saulė, Dessus, Antoine N, Kim, Seung Tea, Klingbeil, Olaf, Liu, Juan, Nowak, Dawid G, Alsudani, Habeeb, Wee, Tse-Luen, Park, Youngkyu, Minicozzi, Francesca, Rivera, Keith, Almeida, Ana S, Chang, Kenneth, Chakrabarty, Ram P, Wilkinson, John E, Gimotty, Phyllis A, Diermeier, Sarah D, Egeblad, Mikala, Vakoc, Christopher R, Locasale, Jason W, Chandel, Navdeep S, Janowitz, Tobias, Hicks, James B, Wigler, Michael, Pappin, Darryl J, Williams, Roger L, Cifani, Paolo, Tuveson, David A, Laporte, Jocelyn, Trotman, Lloyd C (October 2024) Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function. Science, 386 (6720). eadk9167. ISSN 0036-8075

Homer, Joshua A, Johnson, Robert M, Koelln, Rebecca A, Moorhouse, Adam D, Moses, John E (October 2024) Strategic re-engineering of antibiotics. Nature Reviews Bioengineering. ISSN 2731-6092

Zubiete-Franco, Imanol, Tonks, Nicholas K (September 2024) Famotidine increases cellular phospho-tyrosine levels. Biochemical and Biophysical Research Communications, 734. p. 150763. ISSN 0006-291X

Murga, Matilde, Lopez-Pernas, Gema, Soliva, Robert, Fueyo-Marcos, Elena, Amor, Corina, Faustino, Ignacio, Serna, Marina, Serrano, Alicia G, Díaz, Lucía, Martínez, Sonia, Blanco-Aparicio, Carmen, Antón, Marta Elena, Seashore-Ludlow, Brinton, Pastor, Joaquín, Jafari, Rozbeh, Lafarga, Miguel, Llorca, Oscar, Orozco, Modesto, Fernández-Capetillo, Oscar (September 2024) SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis. Cell Death and Disease, 15 (9). p. 694. ISSN 2041-4889 (Public Dataset)

Yang, Xiaochun, Bhowmick, Krishanu, Rao, Shuyun, Xiang, Xiyan, Ohshiro, Kazufumi, Amdur, Richard L, Hassan, Md Imtaiyaz, Mohammad, Taj, Crandall, Keith, Cifani, Paolo, Shetty, Kirti, Lyons, Scott K, Merrill, Joseph R, Vegesna, Anil K, John, Sahara, Latham, Patricia S, Crawford, James M, Mishra, Bibhuti, Dasarathy, Srinivasan, Wang, Xin Wei, Yu, Herbert, Wang, Zhanwei, Huang, Hai, Krainer, Adrian R, Mishra, Lopa (August 2024) Aldehydes alter TGF-β signaling and induce obesity and cancer. Cell Reports, 43 (9). p. 114676. ISSN 2211-1247 (Public Dataset)

Qiu, Yijian, Stamatatos, Olivia T, Hu, Qingting, Ruiter Swain, Jed, Russo, Suzanne, Sann, Ava, Costa, Ana SH, Violante, Sara, Spector, David L, Cross, Justin R, Lukey, Michael J (August 2024) The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade. Nature Metabolism, 6 (8). pp. 1529-1548. ISSN 2522-5812 (Public Dataset)

Klingbeil, Olaf, Skopelitis, Damianos, Tonelli, Claudia, Yoshimoto, Toyoki, Alpsoy, Aktan, Panepinto, Maria C, Minicozzi, Francesca, Merrill, Joseph R, Cafiero, Amanda M, Aggarwal, Disha, Russo, Suzanne, Ha, Taehoon, Demerdash, Osama E, Wee, Tse-Luen, Spector, David L, Lyons, Scott K, Tuveson, David A, Cifani, Paolo, Vakoc, Christopher R (July 2024) MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer. Cancer Discovery. ISSN 2159-8274 (Public Dataset)

Bermejo-Rodriguez, Camino, Araos Henríquez, Joaquín, Caligiuri, Giuseppina, Pinto Teles, Sara, Park, Youngkyu, Evans, Anthony, Barrera, Lawrence N, Neesse, Albrecht, Grutzmann, Robert, Aust, Daniela, Rümmele, Petra, Knösel, Thomas, Narita, Masako, Narita, Masashi, Campbell, Fiona, Öhlund, Daniel, Pilarsky, Christian, Dow, Lukas E, Humbert, Patrick O, Biffi, Giulia, Tuveson, David A, Perez-Mancera, Pedro A (July 2024) Scribble Deficiency Promotes Pancreatic Ductal Adenocarcinoma Development and Metastasis. Cancer Research. ISSN 0008-5472 (Public Dataset)

Benitz, Simone, Steep, Alec, Nasser, Malak M, Preall, Jonathan, Mahajan, Ujjwal Mukund, McQuithey, Holly, Loveless, Ian, Davis, Erick T, Wen, Hui-Ju, Long, Daniel W, Metzler, Thomas, Zwernik, Samuel, Louw, Michaela, Rempinski, Donald, Salas-Escabillas, Daniel J, Brender, Sydney M, Song, Linghao, Huang, Ling, Theisen, Brian K, Zhang, Zhenyu, Steele, Nina G, Regel, Ivonne, Bednar, Filip, Crawford, Howard C (July 2024) ROR2 Regulates Cellular Plasticity in Pancreatic Neoplasia and Adenocarcinoma. Cancer Discovery. ISSN 2159-8274 (Public Dataset)

Bojmar, Linda, Zambirinis, Constantinos P, Hernandez, Jonathan M, Chakraborty, Jayasree, Shaashua, Lee, Kim, Junbum, Johnson, Kofi Ennu, Hanna, Samer, Askan, Gokce, Burman, Jonas, Ravichandran, Hiranmayi, Zheng, Jian, Jolissaint, Joshua S, Srouji, Rami, Song, Yi, Choubey, Ankur, Kim, Han Sang, Cioffi, Michele, van Beek, Elke, Sigel, Carlie, Jessurun, Jose, Velasco Riestra, Paulina, Blomstrand, Hakon, Jönsson, Carolin, Jönsson, Anette, Lauritzen, Pernille, Buehring, Weston, Ararso, Yonathan, Hernandez, Dylanne, Vinagolu-Baur, Jessica P, Friedman, Madison, Glidden, Caroline, Firmenich, Laetitia, Lieberman, Grace, Mejia, Dianna L, Nasar, Naaz, Mutvei, Anders P, Paul, Doru M, Bram, Yaron, Costa-Silva, Bruno, Basturk, Olca, Boudreau, Nancy, Zhang, Haiying, Matei, Irina R, Hoshino, Ayuko, Kelsen, David, Sagi, Irit, Scherz, Avigdor, Scherz-Shouval, Ruth, Yarden, Yosef, Oren, Moshe, Egeblad, Mikala, Lewis, Jason S, Keshari, Kayvan, Grandgenett, Paul M, Hollingsworth, Michael A, Rajasekhar, Vinagolu K, Healey, John H, Björnsson, Bergthor, Simeone, Diane M, Tuveson, David A, Iacobuzio-Donahue, Christine A, Bromberg, Jaqueline, Vincent, C Theresa, O'Reilly, Eileen M, DeMatteo, Ronald P, Balachandran, Vinod P, D'Angelica, Michael I, Kingham, T Peter, Allen, Peter J, Simpson, Amber L, Elemento, Olivier, Sandström, Per, Schwartz, Robert E, Jarnagin, William R, Lyden, David (June 2024) Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer. Nature Medicine. ISSN 1078-8956 (Public Dataset)

Maia-Silva, Diogo, Cunniff, Patrick J, Schier, Allison C, Skopelitis, Damianos, Trousdell, Marygrace C, Moresco, Philip, Gao, Yuan, Kechejian, Vahag, He, Xue-Yan, Sahin, Yunus, Wan, Ledong, Alpsoy, Aktan, Liverpool, Jynelle, Krainer, Adrian R, Egeblad, Mikala, Spector, David L, Fearon, Douglas T, Dos Santos, Camila O, Taatjes, Dylan J, Vakoc, Christopher R (June 2024) Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature Genetics. ISSN 1061-4036

Guo, Guangran, Amor, Corina (June 2024) SGLT2 regulates immune-mediated senolysis. Nature Aging. ISSN 2662-8465

Segovia, Danilo, Adams, Dexter W, Hoffman, Nickolas, Safaric Tepes, Polona, Wee, Tse-Luen, Cifani, Paolo, Joshua-Tor, Leemor, Krainer, Adrian R (May 2024) SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23. Proceedings of the National Academy of Sciences of the United States of America, 121 (21). e2322974121. ISSN 0027-8424 (Public Dataset)

Lupo, Francesca, Pezzini, Francesco, Pasini, Davide, Fiorini, Elena, Adamo, Annalisa, Veghini, Lisa, Bevere, Michele, Frusteri, Cristina, Delfino, Pietro, D'agosto, Sabrina, Andreani, Silvia, Piro, Geny, Malinova, Antonia, Wang, Tian, De Sanctis, Francesco, Lawlor, Rita Teresa, Hwang, Chang-Il, Carbone, Carmine, Amelio, Ivano, Bailey, Peter, Bronte, Vincenzo, Tuveson, David, Scarpa, Aldo, Ugel, Stefano, Corbo, Vincenzo (April 2024) Axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC. Gut. gutjnl-2023. ISSN 0017-5749

Henry, Samantha, Lewis, Steven Macauley, Cyrill, Samantha Leeanne, Callaway, Mackenzie Kate, Chatterjee, Deeptiman, Hanasoge Somasundara, Amritha Varshini, Jones, Gina, He, Xue-Yan, Caligiuri, Giuseppina, Ciccone, Michael Francis, Diaz, Isabella Andrea, Biswas, Amelia Aumalika, Hernandez, Evelyn, Ha, Taehoon, Wilkinson, John Erby, Egeblad, Mikala, Tuveson, David Arthur, Dos Santos, Camila Oresco (April 2024) Host response during unresolved urinary tract infection alters female mammary tissue homeostasis through collagen deposition and TIMP1. Nature Communications, 15 (1). p. 3282. ISSN 2041-1723 (Public Dataset)

Michalski, Kevin, Furukawa, Hiro (April 2024) Structure and function of GluN1-3A NMDA receptor excitatory glycine receptor channel. Science Advances, 10 (15). eadl5952. ISSN 2375-2548

Boelaars, Kelly, Rodriguez, Ernesto, Huinen, Zowi R, Liu, Chang, Wang, Di, Springer, Babet O, Olesek, Katarzyna, Goossens-Kruijssen, Laura, van Ee, Thomas, Lindijer, Dimitri, Tak, Willemijn, de Haas, Aram, Wehry, Laetitia, Nugteren-Boogaard, Joline P, Mikula, Aleksandra, de Winde, Charlotte M, Mebius, Reina E, Tuveson, David A, Giovannetti, Elisa, Bijlsma, Maarten F, Wuhrer, Manfred, van Vliet, Sandra J, van Kooyk, Yvette (April 2024) Pancreatic cancer-associated fibroblasts modulate macrophage differentiation via sialic acid-Siglec interactions. Communications Biology, 7 (1). p. 430. ISSN 2399-3642 (Public Dataset)

Amit, Moran, Anastasaki, Corina, Dantzer, Robert, Demir, Ihsan Ekin, Deneen, Benjamin, Dixon, Karen O, Egeblad, Mikala, Gibson, Erin M, Hervey-Jumper, Shawn L, Hondermarck, Hubert, Magnon, Claire, Monje, Michelle, Na'ara, Shorook, Pan, Yuan, Repasky, Elizabeth A, Scheff, Nicole N, Sloan, Erica K, Talbot, Sebastien, Tracey, Kevin J, Trotman, Lloyd C, Valiente, Manuel, Van Aelst, Linda, Venkataramani, Varun, Venkatesh, Humsa S, Vermeer, Paola D, Winkler, Frank, Wong, Richard J, Gutmann, David H, Borniger, Jeremy C (April 2024) Next Directions in the Neuroscience of Cancers Arising outside the CNS. Cancer Discovery, 14 (4). pp. 669-673. ISSN 2159-8274

Damoci, Chris B, Merrill, Joseph R, Sun, Yanping, Lyons, Scott K, Olive, Kenneth P (March 2024) Addressing Biological Questions with Preclinical Cancer Imaging. Cold Spring Harbor Perspectives in Medicine. a041378-a041378. ISSN 2157-1422

Yashaswini, Chittampalli N, Qin, Tianyue, Bhattacharya, Dipankar, Amor, Corina, Lowe, Scott, Lujambio, Amaia, Wang, Shuang, Friedman, Scott L (March 2024) Phenotypes and ontogeny of senescent hepatic stellate cells in metabolic dysfunction-associated steatotic liver disease. Journal of Hepatology. S0168-8278(24)00197. ISSN 0168-8278

Homer, Joshua A, Koelln, Rebecca A, Barrow, Andrew S, Gialelis, Timothy L, Boiarska, Zlata, Steinohrt, Nikita S, Lee, Erinna F, Yang, Wen-Hsuan, Johnson, Robert M, Chung, Taemoon, Habowski, Amber N, Vishwakarma, Dharmendra S, Bhunia, Debmalya, Avanzi, Charlotte, Moorhouse, Adam D, Jackson, Mary, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Fairlie, W Douglas, Haider, Shozeb M, Steinmetz, Michel O, Prota, Andrea E, Moses, John E (March 2024) Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chemical Science, 15 (11). pp. 3879-3892. ISSN 2041-6520 (Public Dataset)

Ubhi, Tajinder, Zaslaver, Olga, Quaile, Andrew T, Plenker, Dennis, Cao, Pinjiang, Pham, Nhu-An, Békési, Angéla, Jang, Gun-Ho, O'Kane, Grainne M, Notta, Faiyaz, Moffat, Jason, Wilson, Julie M, Gallinger, Steven, Vértessy, Beáta G, Tuveson, David A, Röst, Hannes L, Brown, Grant W (March 2024) Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature Cancer. ISSN 2662-1347 (Public Dataset)

Colucci, Manuel, Zumerle, Sara, Bressan, Silvia, Gianfanti, Federico, Troiani, Martina, Valdata, Aurora, D'Ambrosio, Mariantonietta, Pasquini, Emiliano, Varesi, Angelica, Cogo, Francesca, Mosole, Simone, Dongilli, Cristina, Desbats, Maria Andrea, Contu, Liliana, Revankdar, Ajinkya, Chen, Jingjing, Kalathur, Madhuri, Perciato, Maria Luna, Basilotta, Rossella, Endre, Laczko, Schauer, Stefan, Othman, Alaa, Guccini, Ilaria, Saponaro, Miriam, Maraccani, Luisa, Bancaro, Nicolò, Lai, Ping, Liu, Lei, Pernigoni, Nicolò, Mele, Federico, Merler, Sara, Trotman, Lloyd C, Guarda, Greta, Calì, Bianca, Montopoli, Monica, Alimonti, Andrea (February 2024) Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells. Cancer Cell. S1535-6108(24)00048. ISSN 1535-6108 (Public Dataset)

He, Xue-Yan, Gao, Yuan, Ng, David, Michalopoulou, Evdokia, George, Shanu, Adrover, Jose M, Sun, Lijuan, Albrengues, Jean, Daßler-Plenker, Juliane, Han, Xiao, Wan, Ledong, Wu, Xiaoli Sky, Shui, Longling S, Huang, Yu-Han, Liu, Bodu, Su, Chang, Spector, David L, Vakoc, Christopher R, Van Aelst, Linda, Egeblad, Mikala (February 2024) Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment. Cancer Cell. ISSN 1535-6108

Amor, Corina, Fernández-Maestre, Inés, Chowdhury, Saria, Ho, Yu-Jui, Nadella, Sandeep, Graham, Courtenay, Carrasco, Sebastian E, Nnuji-John, Emmanuella, Feucht, Judith, Hinterleitner, Clemens, Barthet, Valentin JA, Boyer, Jacob A, Mezzadra, Riccardo, Wereski, Matthew G, Tuveson, David A, Levine, Ross L, Jones, Lee W, Sadelain, Michel, Lowe, Scott W (January 2024) Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction. Nature Aging. ISSN 2662-8465 (Public Dataset)

Homer, Joshua A, Sun, Shoujun, Koelln, Rebecca A, Moses, John E (January 2024) Protocol for producing phosphoramidate using phosphorus fluoride exchange click chemistry. STAR Protocols, 5 (1). p. 102824. ISSN 2666-1667

Leibold, Josef, Tsanov, Kaloyan M, Amor, Corina, Ho, Yu-Jui, Sánchez-Rivera, Francisco J, Feucht, Judith, Baslan, Timour, Chen, Hsuan-An, Tian, Sha, Simon, Janelle, Wuest, Alexandra, Wilkinson, John E, Lowe, Scott W (January 2024) Somatic mouse models of gastric cancer reveal genotype-specific features of metastatic disease. Nature Cancer. ISSN 2662-1347

Swamynathan, Manojit, Mathew, Grinu, Aziz, Andrei, Gordon, Chris, Hillowe, Andrew, Wang, Hehe, Jhaveri, Aashna, Kendall, Jude, Cox, Hilary, Giarrizzo, Michael, Azabdaftari, Gissou, Rizzo, Robert C, Diermeier, Sarah D, Ojima, Iwao, Bialkowska, Agnieszka B, Kaczocha, Martin, Trotman, Lloyd C (2024) FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate Cancer. Cancers, 16 (1). p. 60. ISSN 2072-6694

Xu, Jihao, Roe, Jae-Seok, Lee, EunJung, Tonelli, Claudia, Ji, Keely Y, Younis, Omar W, Somervile, Tim DD, Yao, Melissa, Milazzo, Joseph P, Tiriac, Herve, Kolarzyk, Anna M, Lee, Esak, Grem, Jean L, Lazenby, Audrey J, Grunkemeyer, James A, Hollingsworth, Michael A, Grandgenett, Paul M, Borowsky, Alexander D, Park, Youngkyu, Vakoc, Christopher R, Tuveson, David A, Hwang, Chang-Il (December 2023) Engrailed-1 Promotes Pancreatic Cancer Metastasis. Advanced Science. e2308537. ISSN 2198-3844

Perlee, Sarah, Kikuchi, Sota, Nakadai, Tomoyoshi, Masuda, Takeshi, Ohtsuki, Sumio, Matsumoto, Makoto, Rahmutulla, Bahityar, Fukuyo, Masaki, Cifani, Paolo, Kentsis, Alex, Roeder, Robert G, Kaneda, Atsushi, Hoshii, Takayuki (October 2023) SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3. EMBO Reports, 24 (10). e57108. ISSN 1469-221X

Yao, Min, Preall, Jonathan, Yeh, Johannes, Pappin, Darryl J, Cifani, Paolo, Zhao, Yixin, Shen, Sophia, Moresco, Philip, He, Brian, Patel, Hardik, Habowski, Amber N, King, Daniel A, Raphael, Kara L, Rishi, Arvind, Sejpal, Divyesh V, Weiss, Matthew, Tuveson, David, Fearon, Douglas T (September 2023) Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens. JCI Insight. e172449. ISSN 2379-3708 (Public Dataset)

Arteaga, Carlos L, Cleveland, John L, Foti, Margaret, Mesa, Ruben A, Weiner, Louis M, Willman, Cheryl L, Tuveson, David A (September 2023) AACR Cancer Centers Alliance: Fostering Collaboration and Innovation to Advance Lifesaving Scientific Discoveries for Patients. Molecular Cancer Research. OF1-OF3. ISSN 1541-7786

Qian, Zhe, Song, Dongyan, Ipsaro, Jonathan J, Bautista, Carmelita, Joshua-Tor, Leemor, Yeh, Johannes T-H, Tonks, Nicholas K (September 2023) Manipulating PTPRD function with ectodomain antibodies. Genes and Development. ISSN 0890-9369

Sroka, Martyna W, Skopelitis, Damianos, Vermunt, Marit W, Preall, Jonathan B, El Demerdash, Osama, de Almeida, Larissa MN, Chang, Kenneth, Utama, Raditya, Gryder, Berkley, Caligiuri, Giuseppina, Ren, Diqiu, Nalbant, Benan, Milazzo, Joseph P, Tuveson, David A, Dobin, Alexander, Hiebert, Scott W, Stengel, Kristy R, Mantovani, Roberto, Khan, Javed, Kohli, Rahul M, Shi, Junwei, Blobel, Gerd A, Vakoc, Christopher R (September 2023) Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of USA, 120 (36). e2303859120. ISSN 0027-8424 (Public Dataset)

de Ruiter Swain, Jed, Michalopoulou, Evdokia, Noch, Evan K, Lukey, Michael J, Van Aelst, Linda (August 2023) Metabolic partitioning in the brain and its hijacking by glioblastoma. Genes and Development, 37. pp. 681-702. ISSN 0890-9369

Merrill, Joseph R, Inguscio, Alessandra, Chung, Taemoon, Demestichas, Breanna, Garcia, Libia A, Habel, Jill, Lewis, David Y, Janowitz, Tobias, Lyons, Scott K (August 2023) Sensitive, non-immunogenic in vivo imaging of cancer metastases and immunotherapy response. Cell Stress, 7 (8). pp. 59-68. ISSN 2523-0204

Sun, S, Homer, JA, Smedley, CJ, Cheng, QQ, Sharpless, KB, Moses, JE (August 2023) Phosphorus fluoride exchange: Multidimensional catalytic click chemistry from phosphorus connective hubs. Chem, 9 (8). pp. 2128-2143. ISSN 2451-9308

Kleeman, Sam O, Thakir, Tuba Mansoor, Demestichas, Breanna, Mourikis, Nicholas, Loiero, Dominik, Ferrer, Miriam, Bankier, Sean, Riazat-Kesh, Yosef JRA, Lee, Hassal, Chantzichristos, Dimitrios, Regan, Claire, Preall, Jonathan, Sinha, Sarthak, Rosin, Nicole, Yipp, Bryan, de Almeida, Luiz GN, Biernaskie, Jeff, Dufour, Antoine, Tober-Lau, Pinkus, Ruusalepp, Arno, Bjorkegren, Johan LM, Ralser, Markus, Kurth, Florian, Demichev, Vadim, Heywood, Todd, Gao, Qing, Johannsson, Gudmundur, Koelzer, Viktor H, Walker, Brian R, Meyer, Hannah V, Janowitz, Tobias (August 2023) Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy. Cell Genomics, 3 (8). p. 100347. ISSN 2666-979X

Brina, Daniela, Ponzoni, Adele, Troiani, Martina, Calì, Bianca, Pasquini, Emiliano, Attanasio, Giuseppe, Mosole, Simone, Mirenda, Michela, D'Ambrosio, Mariantonietta, Colucci, Manuel, Guccini, Ilaria, Revandkar, Ajinkya, Alajati, Abdullah, Tebaldi, Toma, Donzel, Deborah, Lauria, Fabio, Parhizgari, Nahjme, Valdata, Aurora, Maddalena, Martino, Calcinotto, Arianna, Bolis, Marco, Rinaldi, Andrea, Barry, Simon, Rüschoff, Jan Hendrik, Sabbadin, Marianna, Sumanasuriya, Semini, Crespo, Mateus, Sharp, Adam, Yuan, Wei, Grinu, Mathew, Boyle, Alexandra, Miller, Cynthia, Trotman, Lloyd, Delaleu, Nicolas, Fassan, Matteo, Moch, Holger, Viero, Gabriella, de Bono, Johann, Alimonti, Andrea (August 2023) The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells. Nature Cancer, 4 (8). pp. 1102-1121. ISSN 2662-1347 (Public Dataset)

Nocini, Riccardo, Tondulli, Luca, D'Ambrosio, Consuelo, Luchini, Claudio, Biankin, Andrew V, Casolino, Raffaella, Scarpa, Aldo, ICGC-ARGO, Milella, Michele, Lawlor, Rita T (August 2023) ICGC ARGO precision medicine: genomic profiling-informed prediction of immunotherapy response in two patients with metastatic head and neck squamous cell carcinoma. The Lancet Oncology, 24 (8). pp. 851-853. ISSN 1470-2045

Smedley, Christopher J, Giel, Marie‐Claire, Fallon, Thomas, Moses, John E (July 2023) Ethene‐1,1‐disulfonyl Difluoride (EDSF) for SuFEx Click Chemistry: Synthesis of SuFExable 1,1‐Bissulfonylfluoride Substituted Cyclobutene Hubs. Angewandte Chemie International Edition, 135 (30). ISSN 0044-8249

Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E, Kleeman, Sam O, Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Gao, Qing, Flint, Thomas R, Young, Lisa, Connell, Claire M, Lukey, Michael J, Goncalves, Marcus D, White, Eileen P, Venkitaraman, Ashok R, Janowitz, Tobias (July 2023) Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia. Cell Metabolism, 35 (7). 1147-1162.e7. ISSN 1550-4131

Wan, Ledong, Lin, Kuan-Ting, Rahman, Mohammad Alinoor, Ishigami, Yuma, Wang, Zhikai, Jensen, Mads A, Wilkinson, John E, Park, Youngkyu, Tuveson, David A, Krainer, Adrian R (July 2023) Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer. Cancer Discovery, 13 (7). pp. 1678-1695. ISSN 2159-8274 (Public Dataset)

Yoo, Hye-Been, Moon, Jin Woo, Kim, Hwa-Ryeon, Lee, Hee Seung, Miyabayashi, Koji, Park, Chan Hee, Ge, Sabrina, Zhang, Amy, Tae, Yoo Keung, Sub, Yujin, Park, Hyun-Woo, Gee, Heon Yung, Notta, Faiyaz, Tuveson, David A, Bang, Seungmin, Kim, Mi-Young, Roe, Jae-Seok (July 2023) A TEAD2-Driven Endothelial-Like Program Shapes Basal-Like Differentiation and Metastasis of Pancreatic Cancer. Gastroenterology, 165 (1). 133-148.e17. ISSN 0016-5085

Gialelis, Timothy L, Wang, Zifei, Homer, Joshua A, Yang, Wen-Hsuan, Chung, Taemoon, Hu, Qingting, Smedley, Christopher J, Pawar, Nitin J, Upadhyay, Nitinkumar S, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Moses, John E (April 2023) Inhibition of mitochondrial metabolism by (-)-jerantinine A: synthesis and biological studies in triple-negative breast cancer cells. MedChemComm, 14 (4). pp. 710-714. ISSN 2632-8682

Herrejon Chavez, Florisela, Luo, Hanzhi, Cifani, Paolo, Pine, Alli, Chu, Karen L, Joshi, Suhasini, Barin, Ersilia, Schurer, Alexandra, Chan, Mandy, Chang, Kathryn, Han, Grace YQ, Pierson, Aspen J, Xiao, Michael, Yang, Xuejing, Kuehm, Lindsey M, Hong, Yuning, Nguyen, Diu TT, Chiosis, Gabriela, Kentsis, Alex, Leslie, Christina, Vu, Ly P, Kharas, Michael G (April 2023) RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells. Nature Communications, 14 (1). p. 2290. ISSN 2041-1723 (Public Dataset)

Ottonello, Alessandra, Wyllie, Jessica A, Yahiaoui, Oussama, Sun, Shoujun, Koelln, Rebecca A, Homer, Joshua A, Johnson, Robert M, Murray, Ewan, Williams, Paul, Bolla, Jani R, Robinson, Carol V, Fallon, Thomas, Soares da Costa, Tatiana P, Moses, John E (April 2023) Shapeshifting bullvalene-linked vancomycin dimers as effective antibiotics against multidrug-resistant gram-positive bacteria. Proceedings of the National Academy of Sciences of USA, 120 (15). e2208737120. ISSN 0027-8424

Abrams, Benjamin, Pengo, Thomas, Wee, Tse-Luen, Deagle, Rebecca C, Vuillemin, Nelly, Callahan, Linda M, Smith, Megan A, Kubow, Kristopher E, Girard, Anne-Marie, Rappoport, Joshua Z, Bayles, Carol J, Cameron, Lisa A, Cole, Richard, Brown, Claire M (April 2023) Tissue-Like 3D Standard and Protocols for Microscope Quality Management. Microscopy and Microanalysis, 29 (2). pp. 616-634. ISSN 1431-9276

Chung, Taemoon, Garcia, Libia, Swamynathan, Manojit M, Froeling, Fieke EM, Trotman, Lloyd C, Tuveson, David A, Lyons, Scott K (April 2023) Internally Controlled and Dynamic Optical Measures of Functional Tumor Biology. Analytical Chemistry, 95 (13). pp. 5661-5670. ISSN 0003-2700

Tonks, Nicholas K (April 2023) Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow. IUBMB Life, 75 (4). pp. 337-352. ISSN 1521-6543

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Almeida, Ana S, Fein, Miriam R, Egeblad, Mikala (June 2021) Multi-color Flow Cytometry for Comprehensive Analysis of the Tumor Immune Infiltrate in a Murine Model of Breast Cancer. Bio-protocol, 11 (11). e4012. ISSN 2331-8325

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Sun, Yu-Chi, Chen, Xiaoyin, Fischer, Stephan, Lu, Shaina, Zhan, Huiqing, Gillis, Jesse, Zador, Anthony M (May 2021) Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections. Nature Neuroscience. ISSN 1097-6256

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Silva, Talita M, Borniger, Jeremy C, Alves, Michele Joana, Alzate Correa, Diego, Zhao, Jing, Fadda, Paolo, Toland, Amanda Ewart, Takakura, Ana C, Moreira, Thiago S, Czeisler, Catherine M, Otero, José Javier (April 2021) Machine learning approaches reveal subtle differences in breathing and sleep fragmentation in Phox2b-derived astrocytes ablated mice. Journal of Neurophysiology, 125 (4). pp. 1164-1179. ISSN 0022-3077

Wang, Minghui, Gallo, Nicholas B, Tai, Yilin, Li, Bo, Van Aelst, Linda (April 2021) Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex. Neuron. ISSN 0896-6273

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Hoffmann, Markus, Hofmann-Winkler, Heike, Smith, Joan C, Krüger, Nadine, Arora, Prerna, Sørensen, Lambert K, Søgaard, Ole S, Hasselstrøm, Jørgen Bo, Winkler, Michael, Hempel, Tim, Raich, Lluís, Olsson, Simon, Danov, Olga, Jonigk, Danny, Yamazoe, Takashi, Yamatsuta, Katsura, Mizuno, Hirotaka, Ludwig, Stephan, Noé, Frank, Kjolby, Mads, Braun, Armin, Sheltzer, Jason M, Pöhlmann, Stefan (March 2021) Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine, 65. p. 103255. ISSN 2352-3964

Gao, ChongFeng, Wisniewski, Luke, Liu, Ying, Staal, Ben, Beddows, Ian, Plenker, Dennis, Aldakkak, Mohammed, Hall, Johnathan, Barnett, Daniel, Gouda, Mirna Kheir, Allen, Peter, Drake, Richard, Zureikat, Amer, Huang, Ying, Evans, Douglas, Singhi, Aatur, Brand, Randall E, Tuveson, David A, Tsai, Susan, Haab, Brian B (January 2021) Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA. Clinical Cancer Research, 27 (1). pp. 226-236. ISSN 1078-0432

Biffi, Giulia, Tuveson, David A (January 2021) Diversity and Biology of Cancer-Associated Fibroblasts. Physiological Reviews, 101 (1). pp. 147-176. ISSN 0031-9333

Borniger, Jeremy C, de Lecea, Luis (2021) Peripheral Lipopolyssacharide Rapidly Silences REM-Active LHGABA Neurons. Frontiers in Behavioral Neuroscience, 15. p. 649428. ISSN 1662-5153

Biasci, D., Smoragiewicz, M., Connell, C. M., Wang, Z., Gao, Y., Thaventhiran, J. E. D., Basu, B., Magiera, L., Johnson, T. I., Bax, L., Gopinathan, A., Isherwood, C., Gallagher, F. A., Pawula, M., Hudecova, I., Gale, D., Rosenfeld, N., Barmpounakis, P., Popa, E. C., Brais, R., Godfrey, E., Mir, F., Richards, F. M., Fearon, D. T., Janowitz, T., Jodrell, D. I. (November 2020) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. Proc Natl Acad Sci U S A, 117 (46). pp. 28960-28970. ISSN 0027-8424 (Print)0027-8424

Gaudino, S. J., Beaupre, M., Lin, X., Joshi, P., Rathi, S., McLaughlin, P. A., Kempen, C., Mehta, N., Eskiocak, O., Yueh, B., Blumberg, R. S., van der Velden, A. W. M., Shroyer, K. R., Bialkowska, A. B., Beyaz, S., Kumar, P. (October 2020) IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity. Mucosal Immunol. ISSN 1933-0219

Fein, Miriam R, He, Xue-Yan, Almeida, Ana S, Bružas, Emilis, Pommier, Arnaud, Yan, Ran, Eberhardt, Anaïs, Fearon, Douglas T, Van Aelst, Linda, Wilkinson, John Erby, Dos Santos, Camila O, Egeblad, Mikala (October 2020) Cancer cell CCR2 orchestrates suppression of the adaptive immune response. Journal of Experimental Medicine, 217 (10). ISSN 0022-1007

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Bencze, G., Bencze, S., Rivera, K. D., Watson, J. D., Orfi, L., Tonks, N. K., Pappin, D. J. (August 2020) Mito-oncology agent: fermented extract suppresses the Warburg effect, restores oxidative mitochondrial activity, and inhibits in vivo tumor growth. Sci Rep, 10 (1). p. 14174. ISSN 2045-2322

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Howard, T. S., Cohen, R. D., Nwajiobi, O., Muneeswaran, Z. P., Sim, Y. E., Lahankar, N. N., Yeh, J. T., Raj, M. (August 2018) Amino-Acid-Catalyzed Direct Aldol Bioconjugation. Org Lett. ISSN 1523-7052

Krishnan, N., Felice, C., Rivera, K., Pappin, D. J., Tonks, N. K. (July 2018) DPM-1001 decreased copper levels and ameliorated deficits in a mouse model of Wilson's disease. Genes Dev, 32 (13-14). pp. 944-952. ISSN 0890-9369

Huang, Y. H., Klingbeil, O., He, X. Y., Wu, X. S., Arun, G., Lu, B., Somerville, T. D. D., Milazzo, J. P., Wilkinson, J. E., Demerdash, O. E., Spector, D. L., Egeblad, M., Shi, J., Vakoc, C. R. (July 2018) POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes Dev, 32 (13-14). pp. 915-928. ISSN 0890-9369

Hou, Shurong, Tiriac, Hervé, Sridharan, Banu Priya, Scampavia, Louis, Madoux, Franck, Seldin, Jan, Souza, Glauco R, Watson, Donald, Tuveson, David, Spicer, Timothy P (July 2018) Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening. Slas Discovery, 23 (6). pp. 574-584. ISSN 2472-5552

Zhang, Jiali, Wang, Zuo, Zhang, Siwei, Chen, Yanxun, Xiong, Xuexue, Li, Xiaojuan, Tonks, Nicholas K., Fan, Gaofeng (June 2018) Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER. Cellular Signalling, 50. pp. 100-110. ISSN 0898-6568

Aguirre, A. J., Nowak, J. A., Camarda, N. D., Moffitt, R. A., Ghazani, A. A., Hazar-Rethinam, M., Raghavan, S., Kim, J., Brais, L. K., Ragon, D., Welch, M. W., Reilly, E., McCabe, D., Marini, L., Anderka, K., Helvie, K., Oliver, N., Babic, A., Da Silva, A., Nadres, B., Van Seventer, E. E., Shahzade, H. A., St Pierre, J. P., Burke, K. P., Clancy, T. E., Cleary, J. M., Doyle, L. A., Jajoo, K., McCleary, N. J., Meyerhardt, J. A., Murphy, J. E., Ng, K., Patel, A. K., Perez, K., Rosenthal, M. H., Rubinson, D. A., Ryou, M., Shapiro, G. I., Sicinska, E., Silverman, S. G., Nagy, R. J., Lanman, R. B., Knoerzer, D., Welsch, D. J., Yurgelun, M. B., Fuchs, C. S., Garraway, L. A., Getz, G., Hornick, J. L., Johnson, B. E., Kulke, M. H., Mayer, R. J., Miller, J. W., Shyn, P. B., Tuveson, D. A., Wagle, N., Yeh, J. J., Hahn, W. C., Corcoran, R. B., Carter, S. L., Wolpin, B. M. (June 2018) Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine. Cancer Discov, 8 (9). pp. 1096-1111. ISSN 2159-8274

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Quaranta, V., Rainer, C., Nielsen, S. R., Raymant, M. L., Ahmed, M. S., Engle, D. D., Taylor, A., Murray, T., Campbell, F., Palmer, D. H., Tuveson, D. A., Mielgo, A. (May 2018) Macrophage-derived granulin drives resistance to immune checkpoint inhibition in metastatic pancreatic cancer. Cancer Res, 78 (15). pp. 4253-4269. ISSN 0008-5472

Pommier, A., Anaparthy, N., Memos, N., Kelley, Z. L., Gouronnec, A., Yan, R., Auffray, C., Albrengues, J., Egeblad, M., Iacobuzio-Donahue, C. A., Lyons, S. K., Fearon, D. T. (May 2018) Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases. Science, 360 (394). ISSN 0036-8075

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Naguib, A., Mathew, G., Reczek, C. R., Watrud, K., Ambrico, A., Herzka, T., Salas, I. C., Lee, M. F., El-Amine, N., Zheng, W., Di Francesco, M. E., Marszalek, J. R., Pappin, D. J., Chandel, N. S., Trotman, L. C. (April 2018) Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells. Cell Rep, 23 (1). pp. 58-67. ISSN 2211-1247 (Electronic)

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Wolff, R. A., Wang-Gillam, A., Alvarez, H., Tiriac, H., Engle, D., Hou, S., Groff, A. F., Lucas, A. S., Bernard, V., Allenson, K., Castillo, J., Kim, D., Mulu, F., Huang, J., Stephens, B., Wistuba, I. I., Katz, M., Varadhachary, G., Park, Y., Hicks, J., Chinnaiyan, A., Scampavia, L., Spicer, T., Gerhardinger, C., Maitra, A., Tuveson, D., Rinn, J., Lizee, G., Yee, C., Levine, A. J. (March 2018) Dynamic changes during the treatment of pancreatic cancer. Oncotarget, 9 (19). pp. 14764-14790. ISSN 1949-2553

Krishnan, N., Konidaris, K. F., Gasser, G., Tonks, N. K. (February 2018) A potent, selective and orally bioavailable inhibitor of the protein tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models. J Biol Chem, 293 (5). pp. 1517-1525. ISSN 0021-9258

Goncalves, M. D., Hwang, S. K., Pauli, C., Murphy, C. J., Cheng, Z., Hopkins, B. D., Wu, D., Loughran, R. M., Emerling, B. M., Zhang, G., Fearon, D. T., Cantley, L. C. (January 2018) Fenofibrate prevents skeletal muscle loss in mice with lung cancer. Proc Natl Acad Sci U S A, 115 (4). E743-E752. ISSN 0027-8424

Krishnan, N., Bonham, C. A., Rus, I. A., Shrestha, O. K., Gauss, C. M., Haque, A., Tocilj, A., Joshua-Tor, L., Tonks, N. K. (January 2018) Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development. Nat Commun, 9 (1). p. 283. ISSN 2041-1723

Alexander, J., Kendall, J., McIndoo, J., Rodgers, L., Aboukhalil, R., Levy, D., Stepansky, A., Sun, G., Chobadjiev, L., Riggs, M., Cox, H., Hakker, I., Nowak, D. G., Laze, J., Llukani, E., Srivastava, A., Gruschow, S., Yadav, S. S., Robinson, B. D., Atwal, G., Trotman, L. C., Lepor, H., Hicks, J. B., Wigler, M., Krasnitz, A. (January 2018) Utility of single cell genomics in diagnostic evaluation of prostate cancer. Cancer Res, 78 (2). pp. 348-358. ISSN 0008-5472

Cheng, D., Tuveson, D. (January 2018) Kras in Organoids. Cold Spring Harb Perspect Med, 8 (10). ISSN 2157-1422

Connell, C. M., Raby, S. E. M., Beh, I., Flint, T. R., Williams, E. H., Fearon, D. T., Jodrell, D. I., Janowitz, T. (January 2018) Cancer Immunotherapy Trials Underutilize Immune Response Monitoring. Oncologist, 23 (1). pp. 116-117. ISSN 1083-7159

Aberle, M. R., Burkhart, R. A., Tiriac, H., Olde Damink, S. W. M., Dejong, C. H. C., Tuveson, D. A., van Dam, R. M. (January 2018) Patient-derived organoid models help define personalized management of gastrointestinal cancer. Br J Surg, 105 (2). e48-e60. ISSN 0007-1323

Nakamuta, S., Yang, Y. T., Wang, C. L., Gallo, N. B., Yu, J. R., Tai, Y., Van Aelst, L. (December 2017) Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. J Cell Biol, 216 (12). pp. 4313-4330. ISSN 0021-9525

Balachandran, V. P., Luksza, M., Zhao, J. N., Makarov, V., Moral, J. A., Remark, R., Herbst, B., Askan, G., Bhanot, U., Senbabaoglu, Y., Wells, D. K., Cary, C. I. O., Grbovic-Huezo, O., Attiyeh, M., Medina, B., Zhang, J., Loo, J., Saglimbeni, J., Abu-Akeel, M., Zappasodi, R., Riaz, N., Smoragiewicz, M., Kelley, Z. L., Basturk, O., Gonen, M., Levine, A. J., Allen, P. J., Fearon, D. T., Merad, M., Gnjatic, S., Iacobuzio-Donahue, C. A., Wolchok, J. D., DeMatteo, R. P., Chan, T. A., Greenbaum, B. D., Merghoub, T., Leach, S. D. (November 2017) Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer. Nature, 551 (7681). pp. 512-516. ISSN 0028-0836

Zhang, S., Fan, G., Hao, Y., Hammell, M., Wilkinson, J. E., Tonks, N. K. (October 2017) Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase. Genes Dev, 31 (19). pp. 1939-57. ISSN 0890-9369

Vakoc, C. R., Tuveson, D. A. (October 2017) Soils and Seeds That Initiate Pancreatic Cancer Metastasis. Cancer Discov, 7 (10). pp. 1067-1068. ISSN 2159-8274

Tonelli, C., Chio, I. I. C., Tuveson, D. A. (September 2017) Transcriptional regulation by Nrf2. Antioxid Redox Signal. ISSN 1523-0864

Roe, J. S., Hwang, C. I., Somerville, T. D. D., Milazzo, J. P., Lee, E. J., Da Silva, B., Maiorino, L., Tiriac, H., Young, C. M., Miyabayashi, K., Filippini, D., Creighton, B., Burkhart, R. A., Buscaglia, J. M., Kim, E. J., Grem, J. L., Lazenby, A. J., Grunkemeyer, J. A., Hollingsworth, M. A., Grandgenett, P. M., Egeblad, M., Park, Y., Tuveson, D. A., Vakoc, C. R. (August 2017) Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis. Cell, 170 (5). pp. 875-888. ISSN 0092-8674

Frey, W. D., Chaudhry, A., Slepicka, P. F., Ouellette, A. M., Kirberger, S. E., Pomerantz, W. C. K., Hannon, G. J., Dos Santos, C. O. (July 2017) BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells. Stem Cell Reports, 9 (1). pp. 23-31. ISSN 2213-6711 (Public Dataset)

Connell, C. M., Raby, S., Beh, I., Flint, T., Williams, E., Fearon, D. T., Jodrell, D. I., Janowitz, T. (July 2017) Cancer immunotherapy trial registrations increase exponentially but chronic immunosuppressive glucocorticoid therapy may compromise outcomes. Ann Oncol, 28 (7). pp. 1678-1679. ISSN 0923-7534

Feigin, M. E., Garvin, T., Bailey, P., Waddell, N., Chang, D. K., Kelley, D. R., Shuai, S., Gallinger, S., McPherson, J. D., Grimmond, S. M., Khurana, E., Stein, L. D., Biankin, A. V., Schatz, M. C., Tuveson, D. A. (June 2017) Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma. Nat Genet, 49 (6). pp. 825-833. ISSN 1061-4036

Calvert, A. E., Chalastanis, A., Wu, Y., Hurley, L. A., Kouri, F. M., Bi, Y., Kachman, M., May, J. L., Bartom, E., Hua, Y., Mishra, R. K., Schiltz, G. E., Dubrovskyi, O., Mazar, A. P., Peter, M. E., Zheng, H., James, C. D., Burant, C. F., Chandel, N. S., Davuluri, R. V., Horbinski, C., Stegh, A. H. (May 2017) Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation. Cell Rep, 19 (9). pp. 1858-1873.

English, W. R., Lunt, S. J., Fisher, M., Lefley, D. V., Dhingra, M., Lee, Y. C., Bingham, K., Hurrell, J. E., Lyons, S. K., Kanthou, C., Tozer, G. M. (May 2017) Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma. Cancer Res, 77 (10). pp. 2633-2646. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Flint, Thomas R., Fearon, Douglas T., Janowitz, Tobias (May 2017) Connecting the Metabolic and Immune Responses to Cancer. Trends in Molecular Medicine, 23 (5). pp. 451-464. ISSN 1471-4914

Chio, Iok In Christine, Tuveson, David A. (May 2017) ROS in Cancer: The Burning Question. Trends in Molecular Medicine, 23 (5). pp. 411-429. ISSN 1471-4914

Gurung, Prajwal, Fan, Gaofeng, Lukens, John R., Vogel, Peter, Tonks, Nicholas K., Kanneganti, Thirumala-Devi (April 2017) Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease. Immunity, 46 (4). pp. 635-648. ISSN 1074-7613

Sinha, S., Fu, Y. Y., Grimont, A., Ketcham, M., Lafaro, K. J., Saglimbeni, J. A., Askan, G., Bailey, J. M., Melchor, J. P., Zhong, Y., Joo, M. G., Grbovic-Huezo, O., Yang, I. H., Basturk, O., Baker, L., Park, Y., Kurtz, R. C., Tuveson, D. A., Leach, S. D., Pasricha, P. (April 2017) PanIN neuroendocrine cells promote tumorigenesis via neuronal crosstalk. Cancer Res, 77 (8). pp. 1868-1879. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Fearon, D. T. (April 2017) Explaining the Paucity of Intratumoral T Cells: A Construction Out of Known Entities. Cold Spring Harb Symp Quant Biol, 81. pp. 219-226. ISSN 0091-7451

Tuveson, D. (April 2017) Waging war against pancreatic cancer: an interview with David Tuveson. Dis Model Mech, 10 (4). pp. 353-357. ISSN 1754-8403

Ohlund, D., Handly-Santana, A., Biffi, G., Elyada, E., Almeida, A. S., Ponz-Sarvise, M., Corbo, V., Oni, T. E., Hearn, S. A., Lee, E. J., Chio, II, Hwang, C. I., Tiriac, H., Baker, L. A., Engle, D. D., Feig, C., Kultti, A., Egeblad, M., Fearon, D. T., Crawford, J. M., Clevers, H., Park, Y., Tuveson, D. A. (March 2017) Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med, 214 (3). pp. 579-596. ISSN 0022-1007

Chen, M., Nowak, D. G., Narula, N., Robinson, B., Watrud, K., Ambrico, A., Herzka, T. M., Zeeman, M. E., Minderer, M., Zheng, W., Ebbesen, S. H., Plafker, K. S., Stahlhut, C., Wang, V. M., Wills, L., Nasar, A., Castillo-Martin, M., Cordon-Cardo, C., Wilkinson, J. E., Powers, S., Sordella, R., Altorki, N. K., Mittal, V., Stiles, B. M., Plafker, S. M., Trotman, L. C. (March 2017) The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol, 216 (3). pp. 641-656. ISSN 0021-9525

Vakoc, C. R., Tuveson, D. A. (February 2017) Untangling the genetics from the epigenetics in pancreatic cancer metastasis. Nat Genet, 49 (3). pp. 323-324. ISSN 1061-4036

Senturk, S., Shirole, N. H., Nowak, D. G., Corbo, V., Pal, D., Vaughan, A., Tuveson, D. A., Trotman, L. C., Kinney, J. B., Sordella, R. (February 2017) Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization. Nat Commun, 8. p. 14370. ISSN 2041-1723 (Public Dataset)

Chio, II, Tuveson, D. A. (January 2017) ROS in translation: Chink in the armor. Cell Cycle, 16 (4). pp. 297-298. ISSN 1551-4005

Singh, Dinesh K., Kollipara, Rahul K., Vemireddy, Vamsidara, Yang, Xiao-Li, Sun, Yuxiao, Regmi, Nanda, Klingler, Stefan, Hatanpaa, Kimmo J., Raisanen, Jack, Cho, Steve K., Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara, Mashimo, Tomoyuki, Wang, Shan, Humphries, Caroline G., Mickey, Bruce, Maher, Elizabeth A., Zheng, Hongwu, Kim, Ryung S., Kittler, Ralf, Bachoo, Robert M. (January 2017) Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. Cell Reports, 18 (4). pp. 961-976. ISSN 2211-1247

Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., Hermida, J., Lecanda, F. (January 2017) EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol, 10 (1). p. 23. ISSN 1756-8722 (Electronic)1756-8722 (Linking)

Pal, D., Pertot, A., Shirole, N. H., Yao, Z., Anaparthy, N., Garvin, T., Cox, H., Chang, K., Rollins, F., Kendall, J., Edwards, L., Singh, V. A., Stone, G. C., Schatz, M. C., Hicks, J., Hannon, G., Sordella, R. (January 2017) TGF-beta reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells. Elife, 6. ISSN 2050-084X (Electronic)2050-084X (Linking)

Koh, S. B., Mascalchi, P., Rodriguez, E., Lin, Y., Jodrell, D. I., Richards, F. M., Lyons, S. K. (January 2017) A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level. J Cell Sci, 130 (2). pp. 512-520. ISSN 0021-9533

Ireland, L., Santos, A., Ahmed, M. S., Rainer, C., Nielsen, S. R., Quaranta, V., Weyer-Czernilofsky, U., Engle, D. D., Perez-Mancera, P., Coupland, S. E., Taktak, A. F., Bogenrieder, T., Tuveson, D. A., Campbell, F., Schmid, M. C., Mielgo, A. (December 2016) Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors. Cancer Res, 76 (23). pp. 6851-6863. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Miller, M., Shirole, N., Tian, R., Pal, D., Sordella, R. (December 2016) The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants. J Cancer Biol Res, 4 (4). ISSN 2373-9436

Flint, T. R., Janowitz, T., Connell, C. M., Roberts, E. W., Denton, A. E., Coll, A. P., Jodrell, D. I., Fearon, D. T. (November 2016) Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity. Cell Metab, 24 (5). pp. 672-684. ISSN 1932-7420 (Electronic)1550-4131 (Linking)

Park, J., Wysocki, R. W., Amoozgar, Z., Maiorino, L., Fein, M. R., Jorns, J., Schott, A. F., Kinugasa-Katayama, Y., Lee, Y., Won, N. H., Nakasone, E. S., Hearn, S. A., Kuttner, V., Qiu, J., Almeida, A. S., Perurena, N., Kessenbrock, K., Goldberg, M. S., Egeblad, M. (October 2016) Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Sci Transl Med, 8 (361). 361ra138. ISSN 1946-6242 (Electronic)1946-6234 (Linking)

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Book Section

Chung, Taemoon, Merrill, Joseph R, Lyons, Scott K (2024) CRISPR/Cas for PET Reporter Gene Engineering. In: Methods in Molecular Biology. UNSPECIFIED, pp. 285-301. ISBN 9781071634981

Denton, A. E., Roberts, E. W., Fearon, D. T. (August 2018) Stromal Cells in the Tumor Microenvironment. In: Advances in Experimental Medicine and Biology. Springer International Publishing AG, pp. 99-114.