Items where Community is "Cellular Communication in Cancer Program"

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Paper

Eskiocak, Onur, Chowdhury, Saria, Shah, Vyom, Nnuji-John, Emmanuella, Chung, Charlie, Boyer, Jacob A, Harris, Alexander S, Habel, Jill, Sadelain, Michel, Beyaz, Semir, Amor, Corina (March 2024) Senolytic CAR T cells reverse aging-associated defects in intestinal regeneration and fitness. bioRxiv. (Submitted)

Homer, Joshua A, Koelln, Rebecca A, Barrow, Andrew S, Gialelis, Timothy L, Boiarska, Zlata, Steinohrt, Nikita S, Lee, Erinna F, Yang, Wen-Hsuan, Johnson, Robert M, Chung, Taemoon, Habowski, Amber N, Vishwakarma, Dharmendra S, Bhunia, Debmalya, Avanzi, Charlotte, Moorhouse, Adam D, Jackson, Mary, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Fairlie, W Douglas, Haider, Shozeb M, Steinmetz, Michel O, Prota, Andrea E, Moses, John E (March 2024) Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chemical Science, 15 (11). pp. 3879-3892. ISSN 2041-6520 (Public Dataset)

Ubhi, Tajinder, Zaslaver, Olga, Quaile, Andrew T, Plenker, Dennis, Cao, Pinjiang, Pham, Nhu-An, Békési, Angéla, Jang, Gun-Ho, O'Kane, Grainne M, Notta, Faiyaz, Moffat, Jason, Wilson, Julie M, Gallinger, Steven, Vértessy, Beáta G, Tuveson, David A, Röst, Hannes L, Brown, Grant W (March 2024) Cytidine deaminases APOBEC3C and APOBEC3D promote DNA replication stress resistance in pancreatic cancer cells. Nature Cancer. ISSN 2662-1347 (Public Dataset)

He, Xue-Yan, Gao, Yuan, Ng, David, Michalopoulou, Evdokia, George, Shanu, Adrover, Jose M, Sun, Lijuan, Albrengues, Jean, Daßler-Plenker, Juliane, Han, Xiao, Wan, Ledong, Wu, Xiaoli Sky, Shui, Longling S, Huang, Yu-Han, Liu, Bodu, Su, Chang, Spector, David L, Vakoc, Christopher R, Van Aelst, Linda, Egeblad, Mikala (February 2024) Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment. Cancer Cell. ISSN 1535-6108

Henry, Samantha, Lewis, Steven Macauley, Cyrill, Samantha Leeanne, Callaway, Mackenzie Kate, Chatterjee, Deeptiman, Hanasoge Somasundara, Amritha Varshini, Jones, Gina, He, Xue-Yan, Caligiuri, Giuseppina, Ciccone, Michael Francis, Diaz, Isabella Andrea, Biswas, Amelia, Hernandez, Evelyn, Ha, Taehoon, Wilkinson, John Erby, Egeblad, Mikala, Tuveson, David Arthur, Oresco dos Santos, Camila (February 2024) Host response during unresolved urinary tract infection alters mammary tissue homeostasis through collagen deposition and TIMP1. bioRxiv. (Public Dataset) (Submitted)

M. Swamynathan, Manojit, Mathew, Grinu, Aziz, Andrei, Gordon, Chris, Hillowe, Andrew, Wang, Hehe, Jhaveri, Aashna, Kendall, Jude, Cox, Hilary, Giarrizzo, Michael, Azabdaftari, Gissou, Rizzo, Robert C, Diermeier, Sarah D, Ojima, Iwao, Bialkowska, Agnieszka B, Kaczocha, Martin, Trotman, Lloyd C (2024) FABP5 Inhibition against PTEN-Mutant Therapy Resistant Prostate Cancer. Cancers, 16 (1). p. 60. ISSN 2072-6694

Yao, Min, Preall, Jonathan, Yeh, Johannes, Pappin, Darryl J, Cifani, Paolo, Zhao, Yixin, Shen, Sophia, Moresco, Philip, He, Brian, Patel, Hardik, Habowski, Amber N, King, Daniel A, Raphael, Kara L, Rishi, Arvind, Sejpal, Divyesh V, Weiss, Matthew, Tuveson, David, Fearon, Douglas T (September 2023) Plasma cells in human pancreatic ductal adenocarcinoma secrete antibodies to self-antigens. JCI Insight. e172449. ISSN 2379-3708 (Public Dataset)

Qian, Zhe, Song, Dongyan, Ipsaro, Jonathan J, Bautista, Carmelita, Joshua-Tor, Leemor, Yeh, Johannes T-H, Tonks, Nicholas K (September 2023) Manipulating PTPRD function with ectodomain antibodies. Genes and Development. ISSN 0890-9369

Sroka, Martyna W, Skopelitis, Damianos, Vermunt, Marit W, Preall, Jonathan B, El Demerdash, Osama, de Almeida, Larissa MN, Chang, Kenneth, Utama, Raditya, Gryder, Berkley, Caligiuri, Giuseppina, Ren, Diqiu, Nalbant, Benan, Milazzo, Joseph P, Tuveson, David A, Dobin, Alexander, Hiebert, Scott W, Stengel, Kristy R, Mantovani, Roberto, Khan, Javed, Kohli, Rahul M, Shi, Junwei, Blobel, Gerd A, Vakoc, Christopher R (September 2023) Myo-differentiation reporter screen reveals NF-Y as an activator of PAX3-FOXO1 in rhabdomyosarcoma. Proceedings of the National Academy of Sciences of USA, 120 (36). e2303859120. ISSN 0027-8424 (Public Dataset)

Lei, Pin-Ji, Pereira, Ethel R, Andersson, Patrik, Amoozgar, Zohreh, Van Wijnbergen, Jan Willem, O'Melia, Meghan J, Zhou, Hengbo, Chatterjee, Sampurna, Ho, William W, Posada, Jessica M, Kumar, Ashwin S, Morita, Satoru, Menzel, Lutz, Chung, Charlie, Ergin, Ilgin, Jones, Dennis, Huang, Peigen, Beyaz, Semir, Padera, Timothy P (September 2023) Cancer cell plasticity and MHC-II-mediated immune tolerance promote breast cancer metastasis to lymph nodes. Journal of Experimental Medicine, 220 (9). e20221847. ISSN 0022-1007 (Public Dataset)

de Ruiter Swain, Jed, Michalopoulou, Evdokia, Noch, Evan K, Lukey, Michael J, Van Aelst, Linda (August 2023) Metabolic partitioning in the brain and its hijacking by glioblastoma. Genes and Development, 37. pp. 681-702. ISSN 0890-9369

Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E, Kleeman, Sam O, Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Gao, Qing, Flint, Thomas R, Young, Lisa, Connell, Claire M, Lukey, Michael J, Goncalves, Marcus D, White, Eileen P, Venkitaraman, Ashok R, Janowitz, Tobias (July 2023) Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia. Cell Metabolism, 35 (7). 1147-1162.e7. ISSN 1550-4131

Wan, Ledong, Lin, Kuan-Ting, Rahman, Mohammad Alinoor, Ishigami, Yuma, Wang, Zhikai, Jensen, Mads A, Wilkinson, John E, Park, Youngkyu, Tuveson, David A, Krainer, Adrian R (July 2023) Splicing Factor SRSF1 Promotes Pancreatitis and KRASG12D-Mediated Pancreatic Cancer. Cancer Discovery, 13 (7). pp. 1678-1695. ISSN 2159-8274

Yoo, Hye-Been, Moon, Jin Woo, Kim, Hwa-Ryeon, Lee, Hee Seung, Miyabayashi, Koji, Park, Chan Hee, Ge, Sabrina, Zhang, Amy, Tae, Yoo Keung, Sub, Yujin, Park, Hyun-Woo, Gee, Heon Yung, Notta, Faiyaz, Tuveson, David A, Bang, Seungmin, Kim, Mi-Young, Roe, Jae-Seok (July 2023) A TEAD2-Driven Endothelial-Like Program Shapes Basal-Like Differentiation and Metastasis of Pancreatic Cancer. Gastroenterology, 165 (1). 133-148.e17. ISSN 0016-5085

Yan, Ran, Moresco, Philip, Gegenhuber, Bruno, Fearon, Douglas T (June 2023) T cell-Mediated Development of Stromal Fibroblasts with an Immune-Enhancing Chemokine Profile. Cancer Immunology Research. OF1-OF11. ISSN 2326-6066

Cable, Jennifer, Rathmell, Jeffrey C, Pearce, Erika L, Ho, Ping-Chih, Haigis, Marcia C, Mamedov, Murad R, Wu, Meng-Ju, Kaech, Susan M, Lynch, Lydia, Febbraio, Mark A, Bapat, Sagar P, Hong, Hanna S, Zou, Weiping, Belkaid, Yasmine, Sullivan, Zuri A, Keller, Andrea, Wculek, Stefanie K, Green, Douglas R, Postic, Catherine, Amit, Ido, Benitah, Salvador Aznar, Jones, Russell G, Reina-Campos, Miguel, Torres, Santiago Valle, Beyaz, Semir, Brennan, Donal, O'Neill, Luke AJ, Perry, Rachel J, Brenner, Dirk (May 2023) Immunometabolism at the crossroads of obesity and cancer-a Keystone Symposia report. Annals of the New York Academy of Sciences, 1523 (1). pp. 38-50. ISSN 0077-8923

Gialelis, Timothy L, Wang, Zifei, Homer, Joshua A, Yang, Wen-Hsuan, Chung, Taemoon, Hu, Qingting, Smedley, Christopher J, Pawar, Nitin J, Upadhyay, Nitinkumar S, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Moses, John E (April 2023) Inhibition of mitochondrial metabolism by (-)-jerantinine A: synthesis and biological studies in triple-negative breast cancer cells. MedChemComm, 14 (4). pp. 710-714. ISSN 2632-8682

Mousset, Alexandra, Lecorgne, Enora, Bourget, Isabelle, Lopez, Pascal, Jenovai, Kitti, Cherfils-Vicini, Julien, Dominici, Chloé, Rios, Géraldine, Girard-Riboulleau, Cédric, Liu, Bodu, Spector, David L, Ehmsen, Sidse, Renault, Shufang, Hego, Caroline, Mechta-Grigoriou, Fatima, Bidard, François-Clément, Terp, Mikkel Green, Egeblad, Mikala, Gaggioli, Cédric, Albrengues, Jean (April 2023) Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation. Cancer Cell, 41 (4). 757-775.e10. ISSN 1535-6108 (Public Dataset)

Chung, Taemoon, Garcia, Libia, Swamynathan, Manojit M, Froeling, Fieke EM, Trotman, Lloyd C, Tuveson, David A, Lyons, Scott K (April 2023) Internally Controlled and Dynamic Optical Measures of Functional Tumor Biology. Analytical Chemistry, 95 (13). pp. 5661-5670. ISSN 0003-2700

Tonks, Nicholas K (April 2023) Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow. IUBMB Life, 75 (4). pp. 337-352. ISSN 1521-6543

Caligiuri, Giuseppina, Tuveson, David A (March 2023) Activated fibroblasts in cancer: Perspectives and challenges. Cancer Cell, 41 (3). pp. 434-449. ISSN 1535-6108

Bonham, ChristopherA, Mandati, Vinay, Singh, RakeshK, Pappin, DarrylJ, Tonks, NicholasK (March 2023) Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks. Journal of Biological Chemistry. p. 104582. ISSN 0021-9258

Gao, Yuan, He, Xue-Yan, Wu, Xiaoli S, Huang, Yu-Han, Toneyan, Shushan, Ha, Taehoon, Ipsaro, Jonathan J, Koo, Peter K, Joshua-Tor, Leemor, Bailey, Kelly M, Egeblad, Mikala, Vakoc, Christopher R (January 2023) ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation. Nature Cell Biology. ISSN 1465-7392 (Public Dataset)

Mou, Haiwei, Eskiocak, Onur, Özler, Kadir A, Gorman, Megan, Yue, Junjiayu, Jin, Ying, Wang, Zhikai, Gao, Ya, Janowitz, Tobias, Meyer, Hannah V, Yu, Tianxiong, Wilkinson, John E, Kucukural, Alper, Ozata, Deniz M, Beyaz, Semir (January 2023) CRISPR-induced exon skipping of β-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer. Journal of Pathology. ISSN 0022-3417

Katcher, Arielle, Yueh, Brian, Ozler, Kadir, Nizam, Aaron, Kredentser, Ariel, Chung, Charlie, Frimer, Marina, Goldberg, Gary L, Beyaz, Semir (2023) Establishing patient-derived organoids from human endometrial cancer and normal endometrium. Frontiers in Endocrinology, 14. p. 1059228. ISSN 1664-2392

Burr, Ansen HP, Ji, Junyi, Ozler, Kadir, Mentrup, Heather L, Eskiocak, Onur, Yueh, Brian, Cumberland, Rachel, Menk, Ashley V, Rittenhouse, Natalie, Marshall, Chris W, Chiaranunt, Pailin, Zhang, Xiaoyi, Mullinax, Lauren, Overacre-Delgoffe, Abigail, Cooper, Vaughn S, Poholek, Amanda C, Delgoffe, Greg M, Mollen, Kevin P, Beyaz, Semir, Hand, Timothy W (2023) Excess Dietary Sugar Alters Colonocyte Metabolism and Impairs the Proliferative Response to Damage. Cellular and Molecular Gastroenterology and Hepatology, 16 (2). pp. 287-316. ISSN 2352-345X

Yu, Allen T, Aggarwal, Disha, Pappin, Darryl, Spector, David L (December 2022) Single Oligonucleotide Capture of RNA And Temperature Elution Series ( SOCRATES ) for Identification of RNA-binding Proteins. Bio-protocol, 12 (24). e4572. ISSN 2331-8325

Sun, Lijuan, Han, Xiao, Egeblad, Mikala (December 2022) Isolation of mouse mammary carcinoma-derived macrophages and cancer cells for co-culture assays. STAR Protocols, 3 (4). p. 101833. ISSN 2666-1667 (In Press)

Chen, Hsuan-An, Ho, Yu-Jui, Mezzadra, Riccardo, Adrover, Jose M, Smolkin, Ryan, Zhu, Changyu, Woess, Katharina, Bernstein, Nicholas, Schmitt, Georgia, Fong, Linda, Luan, Wei, Wuest, Alexandra, Tian, Sha, Li, Xiang, Broderick, Caroline, Hendrickson, Ronald C, Egeblad, Mikala, Chen, Zhenghao, Alonso-Curbelo, Direna, Lowe, Scott W (October 2022) Senescence rewires microenvironment sensing to facilitate anti-tumor immunity. Cancer Discovery. CD-22. ISSN 2159-8274

Demyan, Lyudmyla, Habowski, Amber N, Plenker, Dennis, King, Daniel A, Standring, Oliver J, Tsang, Caitlin, St Surin, Luce, Rishi, Arvind, Crawford, James M, Boyd, Jeff, Pasha, Shamsher A, Patel, Hardik, Galluzzo, Zachary, Metz, Christine, Gregersen, Peter K, Fox, Sharon, Valente, Cristina, Abadali, Sonya, Matadial-Ragoo, Steffi, DePeralta, Danielle K, Deutsch, Gary B, Herman, Joseph M, Talamini, Mark A, Tuveson, David A, Weiss, Matthew J (September 2022) Pancreatic Cancer Patient-derived Organoids Can Predict Response to Neoadjuvant Chemotherapy. Annals of Surgery, 276 (3). pp. 450-462. ISSN 0003-4932

Farrell, Brian M, Gerth, Fabian, Yang, Cheng-Hao R, Yeh, Johannes T-H (September 2022) A synthetic KLHL20 ligand to validate CUL3KLHL20 as a potent E3 ligase for targeted protein degradation. Genes and Development, 36 (17-18). pp. 1031-1042. ISSN 0890-9369

Song, Dongyan, Adrover, Jose M, Felice, Christy, Christensen, Lisa N, He, Xue-Yan, Merrill, Joseph R, Wilkinson, John E, Janowitz, Tobias, Lyons, Scott K, Egeblad, Mikala, Tonks, Nicholas K (July 2022) PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils. JCI Insight, 7 (14). e158199. ISSN 2379-3708

Wu, Yue, Berisha, Adrian, Borniger, Jeremy C (July 2022) Neuropeptides in Cancer: Friend and Foe? Advanced Biology. e2200111. ISSN 2701-0198

Berisha, Adrian, Shutkind, Kyle, Borniger, Jeremy C (May 2022) Sleep Disruption and Cancer: Chicken or the Egg? Frontiers in Neuroscience, 16. p. 856235. ISSN 1662-4548

Wu, Xiaoli S, He, Xue-Yan, Ipsaro, Jonathan J, Huang, Yu-Han, Preall, Jonathan B, Ng, David, Shue, Yan Ting, Sage, Julien, Egeblad, Mikala, Joshua-Tor, Leemor, Vakoc, Christopher R (May 2022) OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage. Nature. ISSN 0028-0836

Dmitrieva-Posocco, Oxana, Wong, Andrea C, Lundgren, Patrick, Golos, Aleksandra M, Descamps, Hélène C, Dohnalová, Lenka, Cramer, Zvi, Tian, Yuhua, Yueh, Brian, Eskiocak, Onur, Egervari, Gabor, Lan, Yemin, Liu, Jinping, Fan, Jiaxin, Kim, Jihee, Madhu, Bhoomi, Schneider, Kai Markus, Khoziainova, Svetlana, Andreeva, Natalia, Wang, Qiaohong, Li, Ning, Furth, Emma E, Bailis, Will, Kelsen, Judith R, Hamilton, Kathryn E, Kaestner, Klaus H, Berger, Shelley L, Epstein, Jonathan A, Jain, Rajan, Li, Mingyao, Beyaz, Semir, Lengner, Christopher J, Katona, Bryson W, Grivennikov, Sergei I, Thaiss, Christoph A, Levy, Maayan (April 2022) β-Hydroxybutyrate suppresses colorectal cancer. Nature, 605 (7908). pp. 160-165. ISSN 0028-0836

Fernandez-Vega, Virneliz, Hou, Shurong, Plenker, Dennis, Tiriac, Hervé, Baillargeon, Pierre, Shumate, Justin, Scampavia, Louis, Seldin, Jan, Souza, Glauco R, Tuveson, David A, Spicer, Timothy P (March 2022) Lead Identification using 3D Models of Pancreatic Cancer: Development of 3D Tumor Models for High-throughput Screening. Slas Discovery. ISSN 2472-5552

Gallo, Nicholas B, Berisha, Artan, Van Aelst, Linda (March 2022) Microglia regulate chandelier cell axo-axonic synaptogenesis. Proceedings of the National Academy of Sciences of USA, 119 (11). e2114476119. ISSN 0027-8424

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Plenker, Dennis, Tuveson, David A, Rishi, Arvind, Wilkinson, John E, McCombie, W Richard, Kostroff, Karen, Spector, David L (February 2022) Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics. Cancer Research. ISSN 0008-5472

Brennan, Christina M, Nadella, Sandeep, Zhao, Xiang, Dima, Richard J, Jordan-Martin, Nicole, Demestichas, Breanna R, Kleeman, Sam O, Ferrer, Miriam, von Gablenz, Eva Carlotta, Mourikis, Nicholas, Rubin, Michael E, Adnani, Harsha, Lee, Hassal, Ha, Taehoon, Prum, Soma, Schleicher, Cheryl B, Fox, Sharon S, Ryan, Michael G, Pili, Christina, Goldberg, Gary, Crawford, James M, Goodwin, Sara, Zhang, Xiaoyue, Preall, Jonathan B, Costa, Ana SH, Conigliaro, Joseph, Masci, Joseph R, Yang, Jie, Tuveson, David A, Tracey, Kevin J, Janowitz, Tobias (February 2022) Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial. Gut. ISSN 0017-5749

Adrover, Jose M, Carrau, Lucia, Daßler-Plenker, Juliane, Bram, Yaron, Chandar, Vasuretha, Houghton, Sean, Redmond, David, Merrill, Joseph R, Shevik, Margaret, tenOever, Benjamin R, Lyons, Scott K, Schwartz, Robert E, Egeblad, Mikala (February 2022) Disulfiram inhibits neutrophil extracellular trap formation protecting rodents from acute lung injury and SARS-CoV-2 infection. JCI Insight. ISSN 2379-3708

Lin, Xun, Gaudino, Stephen J, Jang, Kyung Ku, Bahadur, Tej, Singh, Ankita, Banerjee, Anirban, Beaupre, Michael, Chu, Timothy, Wong, Hoi Tong, Kim, Chang-Kyung, Kempen, Cody, Axelrad, Jordan, Huang, Huakang, Khalid, Saba, Shah, Vyom, Eskiocak, Onur, Parks, Olivia B, Berisha, Artan, McAleer, Jeremy P, Good, Misty, Hoshino, Miko, Blumberg, Richard, Bialkowska, Agnieszka B, Gaffen, Sarah L, Kolls, Jay K, Yang, Vincent W, Beyaz, Semir, Cadwell, Ken, Kumar, Pawan (January 2022) IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment. Immunity. ISSN 1074-7613

De Sanctis, Francesco, Lamolinara, Alessia, Boschi, Federico, Musiu, Chiara, Caligola, Simone, Trovato, Rosalinda, Fiore, Alessandra, Frusteri, Cristina, Anselmi, Cristina, Poffe, Ornella, Cestari, Tiziana, Canè, Stefania, Sartoris, Silvia, Giugno, Rosalba, Del Rosario, Giulia, Zappacosta, Barbara, Del Pizzo, Francesco, Fassan, Matteo, Dugnani, Erica, Piemonti, Lorenzo, Bottani, Emanuela, Decimo, Ilaria, Paiella, Salvatore, Salvia, Roberto, Lawlor, Rita Teresa, Corbo, Vincenzo, Park, Youngkyu, Tuveson, David A, Bassi, Claudio, Scarpa, Aldo, Iezzi, Manuela, Ugel, Stefano, Bronte, Vincenzo (January 2022) Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer. Journal for ImmunoTherapy of Cancer, 10 (1). e003549-e003549. ISSN 2051-1426

Maiorino, Laura, Shevik, Margaret, Adrover, José M, Han, Xiao, Georgas, Elias, Wilkinson, John Erby, Seidner, Harrison, Foerschner, Leonie, Tuveson, David A, Qin, Yi-Xian, Egeblad, Mikala (January 2022) Longitudinal Intravital Imaging Through Clear Silicone Windows. Journal of Visualized Experiments (179). ISSN 1940-087X

Hanasoge Somasundara, Amritha Varshini, Moss, Matthew A, Feigman, Mary J, Chen, Chen, Cyrill, Samantha L, Ciccone, Michael F, Trousdell, Marygrace C, Vollbrecht, Macy, Li, Siran, Kendall, Jude, Beyaz, Semir, Wilkinson, John E, Dos Santos, Camila O (December 2021) Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis. Cell Reports, 37 (10). p. 110099. ISSN 2211-1247

Deng, Hanfei, Xiao, Xiong, Yang, Tao, Ritola, Kimberly, Hantman, Adam, Li, Yulong, Huang, Z Josh, Li, Bo (December 2021) A genetically defined insula-brainstem circuit selectively controls motivational vigor. Cell. ISSN 0092-8674

Chu, Timothy H, Khairallah, Camille, Shieh, Jason, Cho, Rhea, Qiu, Zhijuan, Zhang, Yue, Eskiocak, Onur, Thanassi, David G, Kaplan, Mark H, Beyaz, Semir, Yang, Vincent W, Bliska, James B, Sheridan, Brian S (December 2021) γδ T cell IFNγ production is directly subverted by Yersinia pseudotuberculosis outer protein YopJ in mice and humans. PLoS Pathogens, 17 (12). e1010103. ISSN 1553-7374

Lee, Yu-Chen, Lin, Song-Chang, Yu, Guoyu, Zhu, Ming, Song, Jian H, Rivera, Keith, Pappin, Darryl J, Logothetis, Christopher J, Panaretakis, Theocharis, Wang, Guocan, Yu-Lee, Li-Yuan, Lin, Sue-Hwa (November 2021) Prostate tumor-induced stromal reprogramming generates Tenascin C that promotes prostate cancer metastasis through YAP/TAZ inhibition. Oncogene. ISSN 0950-9232

Taranda, Julian, Mathew, Grinu, Watrud, Kaitlin, El-Amine, Nour, Lee, Matthew F, Elowsky, Corey, Bludova, Anastasiia, Escobar Avelar, Sintia, Nowak, Dawid G, Wee, Tse-Luen, Wilkinson, John E, Trotman, Lloyd C, Osten, Pavel (November 2021) Combined whole-organ imaging at single-cell resolution and immunohistochemical analysis of prostate cancer and its liver and brain metastases. Cell Reports, 37 (7). p. 110027. ISSN 2211-1247

Barth, Nicole, Mendive-Tapia, Lorena, Subiros-Funosas, Ramon, Ghashghaie, Ouldouz, Lavilla, Rodolfo, Maiorino, Laura, He, Xue-Yan, Dransfield, Ian, Egeblad, Mikala, Vendrell, Marc (November 2021) A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-induced Cancer Cell Death. Angewandte Chemie International Edition. ISSN 1433-7851

Ge, Eva J, Bush, Ashley I, Casini, Angela, Cobine, Paul A, Cross, Justin R, DeNicola, Gina M, Dou, Q Ping, Franz, Katherine J, Gohil, Vishal M, Gupta, Sanjeev, Kaler, Stephen G, Lutsenko, Svetlana, Mittal, Vivek, Petris, Michael J, Polishchuk, Roman, Ralle, Martina, Schilsky, Michael L, Tonks, Nicholas K, Vahdat, Linda T, Van Aelst, Linda, Xi, Dan, Yuan, Peng, Brady, Donita C, Chang, Christopher J (November 2021) Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews Cancer. ISSN 1474-175X

Borniger, Jeremy C (September 2021) Cancer as a tool for preclinical psychoneuroimmunology. Brain, Behavior, & Immunity - Health. p. 100351. ISSN 2666-3546

Brägelmann, Johannes, Lorenz, Carina, Borchmann, Sven, Nishii, Kazuya, Wegner, Julia, Meder, Lydia, Ostendorp, Jenny, Ast, David F, Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A, Plenker, Dennis, Klein, Sebastian, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K, Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D'Rozario, Joshua, Thomas, Emily S, Li, Henry, Schmitt, Clemens A, George, Julie, Thomas, Roman K, von Karstedt, Silvia, Hartmann, Gunther, Büttner, Reinhard, Ullrich, Roland T, Siveke, Jens T, Ohashi, Kadoaki, Schlee, Martin, Sos, Martin L (September 2021) MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nature Communications, 12 (1). p. 5505. ISSN 2041-1723

Beyaz, Semir, Chung, Charlie, Mou, Haiwei, Bauer-Rowe, Khristian E, Xifaras, Michael E, Ergin, Ilgin, Dohnalova, Lenka, Biton, Moshe, Shekhar, Karthik, Eskiocak, Onur, Papciak, Katherine, Ozler, Kadir, Almeqdadi, Mohammad, Yueh, Brian, Fein, Miriam, Annamalai, Damodaran, Valle-Encinas, Eider, Erdemir, Aysegul, Dogum, Karoline, Shah, Vyom, Alici-Garipcan, Aybuke, Meyer, Hannah V, Özata, Deniz M, Elinav, Eran, Kucukural, Alper, Kumar, Pawan, McAleer, Jeremy P, Fox, James G, Thaiss, Christoph A, Regev, Aviv, Roper, Jatin, Orkin, Stuart H, Yilmaz, Ömer H (September 2021) Dietary suppression of MHC class II expression in intestinal epithelial cells enhances intestinal tumorigenesis. Cell Stem Cell. ISSN 1934-5909

Sun, Lijuan, Kees, Tim, Almeida, Ana Santos, Liu, Bodu, He, Xue-Yan, Ng, David, Han, Xiao, Spector, David L, McNeish, Iain A, Gimotty, Phyllis, Adams, Sylvia, Egeblad, Mikala (September 2021) Activating a collaborative innate-adaptive immune response to control metastasis. Cancer Cell. ISSN 1535-6108

Francis, Nikita, Borniger, Jeremy C (September 2021) Cancer as a homeostatic challenge: the role of the hypothalamus. Trends in Neurosciences. ISSN 0166-2236

Lyons, Scott K, Plenker, Dennis, Trotman, Lloyd C (July 2021) Advances in preclinical evaluation of experimental antibody-drug conjugates. Cancer Drug Resistance, 4. pp. 745-754. ISSN 2578-532X

Nielsen, Sebastian R, Strøbech, Jan E, Horton, Edward R, Jackstadt, Rene, Laitala, Anu, Bravo, Marina C, Maltese, Giorgia, Jensen, Adina RD, Reuten, Raphael, Rafaeva, Maria, Karim, Saadia A, Hwang, Chang-Il, Arnes, Luis, Tuveson, David A, Sansom, Owen J, Morton, Jennifer P, Erler, Janine T (June 2021) Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade. Nature Communications, 12 (1). p. 3414. ISSN 2041-1723

Almeida, Ana S, Fein, Miriam R, Egeblad, Mikala (June 2021) Multi-color Flow Cytometry for Comprehensive Analysis of the Tumor Immune Infiltrate in a Murine Model of Breast Cancer. Bio-protocol, 11 (11). e4012. ISSN 2331-8325

Cheng, Derek K, Oni, Tobiloba E, Thalappillil, Jennifer S, Park, Youngkyu, Ting, Hsiu-Chi, Alagesan, Brinda, Prasad, Nadia V, Addison, Kenneth, Rivera, Keith D, Pappin, Darryl J, Van Aelst, Linda, Tuveson, David A (May 2021) Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proceedings of the National Academy of Sciences of USA, 118 (21). e2016904118-e2016904118. ISSN 0027-8424

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Sun, Yu-Chi, Chen, Xiaoyin, Fischer, Stephan, Lu, Shaina, Zhan, Huiqing, Gillis, Jesse, Zador, Anthony M (May 2021) Integrating barcoded neuroanatomy with spatial transcriptional profiling enables identification of gene correlates of projections. Nature Neuroscience. ISSN 1097-6256

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Silva, Talita M, Borniger, Jeremy C, Alves, Michele Joana, Alzate Correa, Diego, Zhao, Jing, Fadda, Paolo, Toland, Amanda Ewart, Takakura, Ana C, Moreira, Thiago S, Czeisler, Catherine M, Otero, José Javier (April 2021) Machine learning approaches reveal subtle differences in breathing and sleep fragmentation in Phox2b-derived astrocytes ablated mice. Journal of Neurophysiology, 125 (4). pp. 1164-1179. ISSN 0022-3077

Wang, Minghui, Gallo, Nicholas B, Tai, Yilin, Li, Bo, Van Aelst, Linda (April 2021) Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex. Neuron. ISSN 0896-6273

Fearon, Douglas T, Janowitz, Tobias (March 2021) AMD3100/Plerixafor overcomes immune inhibition by the CXCL12-KRT19 coating on pancreatic and colorectal cancer cells. British Journal of Cancer. ISSN 0007-0920

Hoffmann, Markus, Hofmann-Winkler, Heike, Smith, Joan C, Krüger, Nadine, Arora, Prerna, Sørensen, Lambert K, Søgaard, Ole S, Hasselstrøm, Jørgen Bo, Winkler, Michael, Hempel, Tim, Raich, Lluís, Olsson, Simon, Danov, Olga, Jonigk, Danny, Yamazoe, Takashi, Yamatsuta, Katsura, Mizuno, Hirotaka, Ludwig, Stephan, Noé, Frank, Kjolby, Mads, Braun, Armin, Sheltzer, Jason M, Pöhlmann, Stefan (March 2021) Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine, 65. p. 103255. ISSN 2352-3964

Gao, ChongFeng, Wisniewski, Luke, Liu, Ying, Staal, Ben, Beddows, Ian, Plenker, Dennis, Aldakkak, Mohammed, Hall, Johnathan, Barnett, Daniel, Gouda, Mirna Kheir, Allen, Peter, Drake, Richard, Zureikat, Amer, Huang, Ying, Evans, Douglas, Singhi, Aatur, Brand, Randall E, Tuveson, David A, Tsai, Susan, Haab, Brian B (January 2021) Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA. Clinical Cancer Research, 27 (1). pp. 226-236. ISSN 1078-0432

Biffi, Giulia, Tuveson, David A (January 2021) Diversity and Biology of Cancer-Associated Fibroblasts. Physiological Reviews, 101 (1). pp. 147-176. ISSN 0031-9333

Borniger, Jeremy C, de Lecea, Luis (2021) Peripheral Lipopolyssacharide Rapidly Silences REM-Active LHGABA Neurons. Frontiers in Behavioral Neuroscience, 15. p. 649428. ISSN 1662-5153

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Lau, A. N., Li, Z., Danai, L. V., Westermark, A. M., Darnell, A. M., Ferreira, R., Gocheva, V., Sivanand, S., Lien, E. C., Sapp, K. M., Mayers, J. R., Biffi, G., Chin, C. R., Davidson, S. M., Tuveson, D. A., Jacks, T., Matheson, N. J., Yilmaz, O., Vander Heiden, M. G. (July 2020) Dissecting cell-type-specific metabolism in pancreatic ductal adenocarcinoma. Elife, 9. ISSN 2050-084x

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Dasgupta, A., Shukla, S.K., Vernucci, E., King, R.J., Abrego, J., Mulder, S.E., Mullen, N.J., Graves, G., Buettner, K., Thakur, R., Murthy, D., Attri, K.S., Wang, D., Chaika, N.V., Pacheco, C.G., Rai, I., Engle, D. D., Grandgenett, P. M., Punsoni, M., Reames, B.N., Teoh-Fitzgerald, M., Oberley-Deegan, R., Yu, F., Klute, K.A., Hollingsworth, M.A., Zimmerman, M.C., Mehla, K., Sadoshima, J., Tuveson, D. A., Singh, P.K. (July 2020) SIRT1-NOX4 Signaling Axis Regulates Cancer Cachexia. J Exp Med, 217 (7). e20190745. ISSN 0022-1007

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Janowitz, T., Gablenz, E., Pattinson, D., Wang, T.C., Conigliaro, J., Tracey, K., Tuveson, D. (June 2020) Famotidine Use and Quantitative Symptom Tracking for COVID-19 in Non-Hospitalised Patients: A Case Series. Gut, 69 (9). pp. 1592-1597. ISSN 1468-3288

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Feigman, M.J., Moss, M.A., Chen, C., Cyrill, S.L., Cicone, M.F., Trousdell, M.C., Yang, S.-T., Frey, W.D., Wilkinson, J.E., Dos Santos, C. O. (May 2020) Pregnancy Reprograms the Epigenome of Mammary Epithelial Cells and Blocks the Development of Premalignant Lesions. Nat Commun, 11 (1). p. 2649. ISSN 2041-1723

Weber, Andrew G, Chau, Alice S, Egeblad, Mikala, Barnes, Betsy J, Janowitz, Tobias (May 2020) Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series. MedRxiv. (Unpublished)

Janowitz, T., Tuveson, D. A. (May 2020) The Era of COVID-19 and the Rise of Science Collectivism in Cancer Research. Cancer Discov, 10 (7). pp. 913-915. ISSN 2159-8274

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Wilson, J.P., Ipsaro, J. J., Del Giudice, S.N., Turna, N. S., Gauss, C. M., Dusenbury, K.H., Marquart, K., Rivera, K. D., Pappin, D. J. (March 2020) Tryp-N: A Thermostable Protease for the Production of N-terminal Argininyl and Lysinyl Peptides. J Proteome Res, 19 (4). pp. 1459-1469. ISSN 1535-3893 (Public Dataset)

LaComb, J. F., Plenker, D., Tiriac, H., Bucobo, J. C., D'Souza, L.S., Khokhar, A.S., Patel, H., Channer, B., Joseph, D., Wu, M., Tuveson, D. A., Li, E., Buscaglia, J. M. (February 2020) Single-Pass vs 2-Pass Endoscopic Ultrasound-Guided Fine-Needle Biopsy Sample Collection for Creation of Pancreatic Adenocarcinoma Organoids. Clin Gastroenterol Hepatol. ISSN 1542-3565

Moral, J.A., Leung, J., Rojas, L.A., Ruan, J., Zhao, J., Sethna, Z., Ramnarain, A., Gasmi, B., Gururajan, M., Redmond, D., Askan, G., Bhanot, U., Elyada, E., Park, Y., Tuveson, D. A., Gonen, M., Leach, S.D., Wolchok, J.D., DeMatteo, R. P., Merghoub, T., Balachandran, V. P. (February 2020) ILC2s Amplify PD-1 Blockade by Activating Tissue-Specific Cancer Immunity. Nature, 579 (7797). pp. 130-135. ISSN 0028-0836 (Public Dataset)

Tian, C., Ohlund, D., Rickelt, S., Lidstrom, T., Huang, Y., Hao, L., Zhao, R. T., Franklin, O., Bhatia, S. N., Tuveson, D. A., Hynes, R. O. (February 2020) Cancer-cell-derived matrisome proteins promote metastasis in pancreatic ductal adenocarcinoma. Cancer Res, 80 (7). pp. 1461-1474. ISSN 0008-5472

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Connell, Claire M, Brais, Rebecca, Whitaker, Hayley, Upponi, Sara, Beh, Ian, Risdall, Jane, Corrie, Pippa, Janowitz, Tobias, Jodrell, Duncan I (January 2020) Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report. BMC Cancer, 20 (1). p. 38. ISSN 1471-2407

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Cheung, E. C., DeNicola, G. M., Nixon, C., Blyth, K., Labuschagne, C. F., Tuveson, D. A., Vousden, K. H. (January 2020) Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. ISSN 1535-6108

Chan-Seng-Yue, M., Kim, J. C., Wilson, G. W., Ng, K., Figueroa, E. F., O'Kane, G. M., Connor, A. A., Denroche, R. E., Grant, R. C., McLeod, J., Wilson, J. M., Jang, G. H., Zhang, A., Liang, S. B., Borgida, A., Chadwick, D., Kalimuthu, S., Lungu, I., Bartlett, J. M. S., Krzyzanowski, P. M., Sandhu, V., Tiriac, H., Froeling, F. E. M., Karasinska, J. M., Topham, J. T., Renouf, D. J., Schaeffer, D. F., Jones, S. J. M., Marra, M. A., Laskin, J., Chetty, R., Stein, L. D., Zogopoulos, G., Haibe-Kains, B., Campbell, P. J., Tuveson, D. A., Knox, J. J., Fischer, S. E., Gallinger, S., Notta, F. (January 2020) Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution. Nat Genet. ISSN 1061-4036 (Public Dataset)

Sindhwani, S., Syed, A.M., Ngai, J., Kingston, B.R., Maiorino, L., Rothschild, J., MacMillan, P., Zhang, Y., Rajesh, N.U., Hoang, T., Wu, J.L.Y., Wilhelm, S., Zilman, A., Gadde, S., Sulaiman, A., Ouyang, B., Lin, Z., Wang, L., Egeblad, M., Chan, W.C.W. (January 2020) The entry of nanoparticles into solid tumours. Nat Mater. ISSN 1476-1122 (Public Dataset)

Munir, Hafsa, Jones, James O, Janowitz, Tobias, Martins, Carla P, Welsh, Sarah J, Shields, Jacqueline D (January 2020) Stromal Amyloid β drives Neutrophil extracellular trap formation to augment tumour growth. BioRxiv. (Unpublished)

Londhe, A. D., Bergeron, A., Curley, S. M., Zhang, F., Rivera, K. D., Kannan, A., Coulis, G., Rizvi, S. H. M., Kim, S. J., Pappin, D. J., Tonks, N. K., Linhardt, R. J., Boivin, B. (December 2019) Regulation of PTP1B activation through disruption of redox-complex formation. Nat Chem Biol, 16 (2). pp. 122-125. ISSN 1552-4450

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Driehuis, E., Kolders, S., Spelier, S., Lohmussaar, K., Willems, S. M., Devriese, L. A., de Bree, R., de Ruiter, E. J., Korving, J., Begthel, H., Van Es, J. H., Geurts, V., He, G. W., van Jaarsveld, R. H., Oka, R., Muraro, M. J., Vivie, J., Zandvliet, Mmjm, Hendrickx, A. P. A., Iakobachvili, N., Sridevi, P., Kranenburg, O., van Boxtel, R., Kops, Gjpl, Tuveson, D. A., Peters, P. J., van Oudenaarden, A., Clevers, H. (May 2019) Oral mucosal organoids as a potential platform for personalized cancer therapy. Cancer Discov, 9 (7). pp. 852-871. ISSN 2159-8274

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Vakoc, C. R., Tuveson, D. A. (October 2017) Soils and Seeds That Initiate Pancreatic Cancer Metastasis. Cancer Discov, 7 (10). pp. 1067-1068. ISSN 2159-8274

Tonelli, C., Chio, I. I. C., Tuveson, D. A. (September 2017) Transcriptional regulation by Nrf2. Antioxid Redox Signal. ISSN 1523-0864

Roe, J. S., Hwang, C. I., Somerville, T. D. D., Milazzo, J. P., Lee, E. J., Da Silva, B., Maiorino, L., Tiriac, H., Young, C. M., Miyabayashi, K., Filippini, D., Creighton, B., Burkhart, R. A., Buscaglia, J. M., Kim, E. J., Grem, J. L., Lazenby, A. J., Grunkemeyer, J. A., Hollingsworth, M. A., Grandgenett, P. M., Egeblad, M., Park, Y., Tuveson, D. A., Vakoc, C. R. (August 2017) Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis. Cell, 170 (5). pp. 875-888. ISSN 0092-8674

Frey, W. D., Chaudhry, A., Slepicka, P. F., Ouellette, A. M., Kirberger, S. E., Pomerantz, W. C. K., Hannon, G. J., Dos Santos, C. O. (July 2017) BPTF Maintains Chromatin Accessibility and the Self-Renewal Capacity of Mammary Gland Stem Cells. Stem Cell Reports, 9 (1). pp. 23-31. ISSN 2213-6711 (Public Dataset)

Connell, C. M., Raby, S., Beh, I., Flint, T., Williams, E., Fearon, D. T., Jodrell, D. I., Janowitz, T. (July 2017) Cancer immunotherapy trial registrations increase exponentially but chronic immunosuppressive glucocorticoid therapy may compromise outcomes. Ann Oncol, 28 (7). pp. 1678-1679. ISSN 0923-7534

Feigin, M. E., Garvin, T., Bailey, P., Waddell, N., Chang, D. K., Kelley, D. R., Shuai, S., Gallinger, S., McPherson, J. D., Grimmond, S. M., Khurana, E., Stein, L. D., Biankin, A. V., Schatz, M. C., Tuveson, D. A. (June 2017) Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma. Nat Genet, 49 (6). pp. 825-833. ISSN 1061-4036

Calvert, A. E., Chalastanis, A., Wu, Y., Hurley, L. A., Kouri, F. M., Bi, Y., Kachman, M., May, J. L., Bartom, E., Hua, Y., Mishra, R. K., Schiltz, G. E., Dubrovskyi, O., Mazar, A. P., Peter, M. E., Zheng, H., James, C. D., Burant, C. F., Chandel, N. S., Davuluri, R. V., Horbinski, C., Stegh, A. H. (May 2017) Cancer-Associated IDH1 Promotes Growth and Resistance to Targeted Therapies in the Absence of Mutation. Cell Rep, 19 (9). pp. 1858-1873.

English, W. R., Lunt, S. J., Fisher, M., Lefley, D. V., Dhingra, M., Lee, Y. C., Bingham, K., Hurrell, J. E., Lyons, S. K., Kanthou, C., Tozer, G. M. (May 2017) Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma. Cancer Res, 77 (10). pp. 2633-2646. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Flint, Thomas R., Fearon, Douglas T., Janowitz, Tobias (May 2017) Connecting the Metabolic and Immune Responses to Cancer. Trends in Molecular Medicine, 23 (5). pp. 451-464. ISSN 1471-4914

Chio, Iok In Christine, Tuveson, David A. (May 2017) ROS in Cancer: The Burning Question. Trends in Molecular Medicine, 23 (5). pp. 411-429. ISSN 1471-4914

Gurung, Prajwal, Fan, Gaofeng, Lukens, John R., Vogel, Peter, Tonks, Nicholas K., Kanneganti, Thirumala-Devi (April 2017) Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease. Immunity, 46 (4). pp. 635-648. ISSN 1074-7613

Sinha, S., Fu, Y. Y., Grimont, A., Ketcham, M., Lafaro, K. J., Saglimbeni, J. A., Askan, G., Bailey, J. M., Melchor, J. P., Zhong, Y., Joo, M. G., Grbovic-Huezo, O., Yang, I. H., Basturk, O., Baker, L., Park, Y., Kurtz, R. C., Tuveson, D. A., Leach, S. D., Pasricha, P. (April 2017) PanIN neuroendocrine cells promote tumorigenesis via neuronal crosstalk. Cancer Res, 77 (8). pp. 1868-1879. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Fearon, D. T. (April 2017) Explaining the Paucity of Intratumoral T Cells: A Construction Out of Known Entities. Cold Spring Harb Symp Quant Biol, 81. pp. 219-226. ISSN 0091-7451

Tuveson, D. (April 2017) Waging war against pancreatic cancer: an interview with David Tuveson. Dis Model Mech, 10 (4). pp. 353-357. ISSN 1754-8403

Ohlund, D., Handly-Santana, A., Biffi, G., Elyada, E., Almeida, A. S., Ponz-Sarvise, M., Corbo, V., Oni, T. E., Hearn, S. A., Lee, E. J., Chio, II, Hwang, C. I., Tiriac, H., Baker, L. A., Engle, D. D., Feig, C., Kultti, A., Egeblad, M., Fearon, D. T., Crawford, J. M., Clevers, H., Park, Y., Tuveson, D. A. (March 2017) Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med, 214 (3). pp. 579-596. ISSN 0022-1007

Chen, M., Nowak, D. G., Narula, N., Robinson, B., Watrud, K., Ambrico, A., Herzka, T. M., Zeeman, M. E., Minderer, M., Zheng, W., Ebbesen, S. H., Plafker, K. S., Stahlhut, C., Wang, V. M., Wills, L., Nasar, A., Castillo-Martin, M., Cordon-Cardo, C., Wilkinson, J. E., Powers, S., Sordella, R., Altorki, N. K., Mittal, V., Stiles, B. M., Plafker, S. M., Trotman, L. C. (March 2017) The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol, 216 (3). pp. 641-656. ISSN 0021-9525

Vakoc, C. R., Tuveson, D. A. (February 2017) Untangling the genetics from the epigenetics in pancreatic cancer metastasis. Nat Genet, 49 (3). pp. 323-324. ISSN 1061-4036

Senturk, S., Shirole, N. H., Nowak, D. G., Corbo, V., Pal, D., Vaughan, A., Tuveson, D. A., Trotman, L. C., Kinney, J. B., Sordella, R. (February 2017) Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization. Nat Commun, 8. p. 14370. ISSN 2041-1723 (Public Dataset)

Chio, II, Tuveson, D. A. (January 2017) ROS in translation: Chink in the armor. Cell Cycle, 16 (4). pp. 297-298. ISSN 1551-4005

Singh, Dinesh K., Kollipara, Rahul K., Vemireddy, Vamsidara, Yang, Xiao-Li, Sun, Yuxiao, Regmi, Nanda, Klingler, Stefan, Hatanpaa, Kimmo J., Raisanen, Jack, Cho, Steve K., Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara, Mashimo, Tomoyuki, Wang, Shan, Humphries, Caroline G., Mickey, Bruce, Maher, Elizabeth A., Zheng, Hongwu, Kim, Ryung S., Kittler, Ralf, Bachoo, Robert M. (January 2017) Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. Cell Reports, 18 (4). pp. 961-976. ISSN 2211-1247

Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., Hermida, J., Lecanda, F. (January 2017) EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol, 10 (1). p. 23. ISSN 1756-8722 (Electronic)1756-8722 (Linking)

Pal, D., Pertot, A., Shirole, N. H., Yao, Z., Anaparthy, N., Garvin, T., Cox, H., Chang, K., Rollins, F., Kendall, J., Edwards, L., Singh, V. A., Stone, G. C., Schatz, M. C., Hicks, J., Hannon, G., Sordella, R. (January 2017) TGF-beta reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24- cancer cells. Elife, 6. ISSN 2050-084X (Electronic)2050-084X (Linking)

Koh, S. B., Mascalchi, P., Rodriguez, E., Lin, Y., Jodrell, D. I., Richards, F. M., Lyons, S. K. (January 2017) A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level. J Cell Sci, 130 (2). pp. 512-520. ISSN 0021-9533

Ireland, L., Santos, A., Ahmed, M. S., Rainer, C., Nielsen, S. R., Quaranta, V., Weyer-Czernilofsky, U., Engle, D. D., Perez-Mancera, P., Coupland, S. E., Taktak, A. F., Bogenrieder, T., Tuveson, D. A., Campbell, F., Schmid, M. C., Mielgo, A. (December 2016) Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors. Cancer Res, 76 (23). pp. 6851-6863. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Miller, M., Shirole, N., Tian, R., Pal, D., Sordella, R. (December 2016) The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants. J Cancer Biol Res, 4 (4). ISSN 2373-9436

Flint, T. R., Janowitz, T., Connell, C. M., Roberts, E. W., Denton, A. E., Coll, A. P., Jodrell, D. I., Fearon, D. T. (November 2016) Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity. Cell Metab, 24 (5). pp. 672-684. ISSN 1932-7420 (Electronic)1550-4131 (Linking)

Park, J., Wysocki, R. W., Amoozgar, Z., Maiorino, L., Fein, M. R., Jorns, J., Schott, A. F., Kinugasa-Katayama, Y., Lee, Y., Won, N. H., Nakasone, E. S., Hearn, S. A., Kuttner, V., Qiu, J., Almeida, A. S., Perurena, N., Kessenbrock, K., Goldberg, M. S., Egeblad, M. (October 2016) Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Sci Transl Med, 8 (361). 361ra138. ISSN 1946-6242 (Electronic)1946-6234 (Linking)

Shirole, N. H., Pal, D., Kastenhuber, E. R., Senturk, S., Boroda, J., Pisterzi, P., Miller, M., Munoz, G., Anderluh, M., Ladanyi, M., Lowe, S. W., Sordella, R. (October 2016) TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions. Elife, 5. ISSN 2050-084X (Electronic)2050-084X (Linking)

Chio, Iok In Christine, Jafarnejad, Seyed Mehdi, Ponz-Sarvise, Mariano, Park, Youngkyu, Rivera, Keith, Palm, Wilhelm, Wilson, John, Sangar, Vineet, Hao, Yuan, Öhlund, Daniel, Wright, Kevin, Filippini, Dea, Lee, Eun Jung, Da Silva, Brandon, Schoepfer, Christina, Wilkinson, John Erby, Buscaglia, Jonathan M, DeNicola, Gina M, Tiriac, Herve, Hammell, Molly, Crawford, Howard C, Schmidt, Edward E, Thompson, Craig B, Pappin, Darryl J, Sonenberg, Nahum, Tuveson, David A (August 2016) NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell, 166 (4). pp. 963-976. ISSN 0092-8674

Gerhard, D. S., Clemons, P. A., Shamji, A. F., Hon, C., Wagner, B. K., Schreiber, S. L., Krasnitz, A., Sordella, R., Sander, C., Lowe, S. W., Powers, S., Smith, K., Aburi, M., Iavarone, A., Lasorella, A., Silva, J., Stockwell, B. R., Califano, A., Boehm, J. S., Vazquez, F., Weir, B. A., Hahn, W. C., Khuri, F. R., Moreno, C. S., Johns, M., Fu, H., Nikolova, O., Mendez, E., Gadi, V. K., Margolin, A. A., Grandori, C., Kemp, C. J., Warren, E. H., Riddell, S. R., McIntosh, M. W., Gevaert, O., Kuo, C. J., Ji, H. P., Dhruv, H., Finlay, D., Kiefer, J., Kim, S., Vuori, K., Berens, M. E., Hangauer, M., Boettcher, M., Weissman, J. S., Bivona, T. G., Bandyopadhyay, S., McManus, M. T., McCormick, F., Aksoy, O., Simonds, E. F., Zheng, T., Chen, J., An, Z., Balmain, A., Weiss, W. A., Chen, K., Liang, H., Scott, K. L., Mills, G. B., Posner, B. A., MacMillan, J., Minna, J., White, M., Roth, M. G., Jagu, S., Mazerik, J. (July 2016) Transforming Big Data into cancer-relevant insight: An initial, multi-tier approach to assess reproducibility and relevance. Mol Cancer Res. ISSN 1557-3125 (Electronic)1541-7786 (Linking)

Fan, G., Zhang, S., Gao, Y., Greer, P. A., Tonks, N. K. (July 2016) HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer. Genes Dev, 30 (13). pp. 1542-57. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Li, J., Sordella, R., Powers, S. (June 2016) Effectors and potential targets selectively upregulated in human KRAS-mutant lung adenocarcinomas. Sci Rep, 6. p. 27891. ISSN 2045-2322 (Electronic)2045-2322 (Linking)

Herrera, V. L., Steffen, M., Moran, A. M., Tan, G. A., Pasion, K. A., Rivera, K., Pappin, D. J., Ruiz-Opazo, N. (June 2016) Confirmation of translatability and functionality certifies the dual endothelin1/VEGFsp receptor (DEspR) protein. BMC Mol Biol, 17 (1). p. 15. ISSN 1471-2199 (Electronic)1471-2199 (Linking)

Ohman, K. A., Hashim, Y. M., Vangveravong, S., Nywening, T. M., Cullinan, D. R., Goedegebuure, S. P., Liu, J., Van Tine, B. A., Tiriac, H., Tuveson, D. A., DeNardo, D. G., Spitzer, D., Mach, R. H., Hawkins, W. G. (June 2016) Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic. Oncotarget, 7 (23). pp. 33529-33541. ISSN 1949-2553 (Electronic)1949-2553 (Linking)

Labbe, D. P., Uetani, N., Vinette, V., Lessard, L., Aubry, I., Migon, E., Sirois, J., Haigh, J., Begin, L. R., Trotman, L. C., Paquet, M., Tremblay, M. L. (June 2016) PTP1B deficiency enables the ability of a high fat diet to drive the invasive character of PTEN-deficient prostate cancers. Cancer Res, 76 (11). pp. 3130-3135. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Asim, M., Massie, C. E., Orafidiya, F., Pertega-Gomes, N., Warren, A. Y., Esmaeili, M., Selth, L. A., Zecchini, H. I., Luko, K., Qureshi, A., Baridi, A., Menon, S., Madhu, B., Escriu, C., Lyons, S., Vowler, S. L., Zecchini, V. R., Shaw, G., Hessenkemper, W., Russell, R., Mohammed, H., Stefanos, N., Lynch, A. G., Grigorenko, E., D'Santos, C., Taylor, C., Lamb, A., Sriranjan, R., Yang, J., Stark, R., Dehm, S. M., Rennie, P. S., Carroll, J. S., Griffiths, J. R., Tavare, S., Mills, I. G., McEwan, I. J., Baniahmad, A., Tilley, W. D., Neal, D. E. (May 2016) Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target. J Natl Cancer Inst, 108 (5). ISSN 1460-2105 (Electronic)0027-8874 (Linking)

Nielsen, S. R., Quaranta, V., Linford, A., Emeagi, P., Rainer, C., Santos, A., Ireland, L., Sakai, T., Sakai, K., Kim, Y. S., Engle, D., Campbell, F., Palmer, D., Ko, J. H., Tuveson, D. A., Hirsch, E., Mielgo, A., Schmid, M. C. (April 2016) Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis. Nat Cell Biol, 18 (5). pp. 549-60. ISSN 1476-4679 (Electronic)1465-7392 (Linking)

Jenkinson, C., Elliott, V., Evans, A., Oldfield, L., Jenkins, R. E., O'Brien, D. P., Apostolidou, S., Gentry-Maharaj, A., Fourkala, E. O., Jacobs, I., Menon, U., Cox, T. F., Campbell, F., Pereira, S. P., Tuveson, D. A., Park, P. K., Greenhalf, W., Sutton, R. Professor, Timms, J. F., Neoptolemos, J., Costello, E. (April 2016) Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus. Clin Cancer Res, 22 (7). pp. 1734-43. ISSN 1078-0432 (Electronic)1078-0432 (Linking)

Baker, Lindsey A., Tiriac, Hervé, Clevers, Hans, Tuveson, David A. (April 2016) Modeling Pancreatic Cancer with Organoids. Trends in Cancer, 2 (4). pp. 176-190. ISSN 2405-8033

Serrao, E. M., Kettunen, M. I., Rodrigues, T. B., Dzien, P., Wright, A. J., Gopinathan, A., Gallagher, F. A., Lewis, D. Y., Frese, K. K., Almeida, J., Howat, W. J., Tuveson, D. A., Brindle, K. M. (March 2016) MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model. Gut, 65 (3). pp. 465-75. ISSN 1468-3288 (Electronic)0017-5749 (Linking)

Ho, J. M., Reynolds, N. M., Rivera, K., Connolly, M., Guo, L. T., Ling, J. Q., Pappin, D. J., Church, G. M., Soll, D. (February 2016) Efficient Reassignment of a Frequent Serine Codon in Wild-Type Escherichia coli. ACS Synthetic Biology, 5 (2). pp. 163-171. ISSN 2161-5063

Arun, G., Diermeier, S., Akerman, M., Chang, K. C., Wilkinson, J. E., Hearn, S., Kim, Y., MacLeod, A. R., Krainer, A. R., Norton, L., Brogi, E., Egeblad, M., Spector, D. L. (January 2016) Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes Dev, 30 (1). pp. 34-51. ISSN 1549-5477 (Electronic)0890-9369 (Linking) (Public Dataset)

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Feigin, M. E., Tuveson, D. A. (2016) Challenges and Opportunities in Modeling Pancreatic Cancer. Cold Spring Harb Symp Quant Biol, 81. pp. 231-235. ISSN 0091-7451

Shen, Chen, Ipsaro, Jonathan J, Shi, Junwei, Milazzo, Joseph P, Wang, Eric, Roe, Jae-Seok, Suzuki, Yutaka, Pappin, Darryl J, Joshua-Tor, Leemor, Vakoc, Christopher R (December 2015) NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler. Molecular Cell, 60 (6). pp. 847-859. ISSN 1097-2765

Yun, J., Mullarky, E., Lu, C., Bosch, K. N., Kavalier, A., Rivera, K., Roper, J., Chio, II, Giannopoulou, E. G., Rago, C., Muley, A., Asara, J. M., Paik, J., Elemento, O., Chen, Z., Pappin, D. J., Dow, L. E., Papadopoulos, N., Gross, S. S., Cantley, L. C. (December 2015) Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science, 350 (6266). pp. 1391-1396. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

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Book Section

Denton, A. E., Roberts, E. W., Fearon, D. T. (August 2018) Stromal Cells in the Tumor Microenvironment. In: Advances in Experimental Medicine and Biology. Springer International Publishing AG, pp. 99-114.

This list was generated on Thu Mar 28 21:36:43 2024 EDT.
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