Waging war against pancreatic cancer: an interview with David Tuveson

Tuveson, D. (April 2017) Waging war against pancreatic cancer: an interview with David Tuveson. Dis Model Mech, 10 (4). pp. 353-357. ISSN 1754-8403

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URL: https://www.ncbi.nlm.nih.gov/pubmed/28381597
DOI: 10.1242/dmm.029975


David Tuveson, Director of the Cancer Center at Cold Spring Harbor Laboratory, is a clinician-scientist with a longstanding interest in understanding and treating pancreatic cancer. Since developing the first mouse model of pancreatic cancer in 2002, the Tuveson lab has made a series of discoveries that shed light on the molecular drivers of this disease and provide promising therapeutic avenues for a malignancy that is notoriously challenging to treat. In collaboration with Hans Clevers, David developed the first pancreatic cancer organoids, which revolutionized the field by providing a powerful model system for basic discoveries and advancement of personalized medicine. Here, David talks to Ross Cagan about his path from chemistry student to world-renowned oncologist, highlighting how his colleagues, mentors and patient interactions shaped his research interests and unique approach to scientific discovery. As well as discussing the story behind some of his breakthroughs, he provides tips on running a lab and succeeding in or outside academia.

Item Type: Paper
Subjects: educational material
CSHL Authors:
Communities: CSHL Cancer Center Program > Signal Transduction
CSHL Cancer Center Program > Cellular Communication in Cancer Program
CSHL labs > Tuveson lab
Depositing User: Matt Covey
Date: 1 April 2017
Date Deposited: 12 Apr 2017 16:03
Last Modified: 07 Jul 2021 18:54
PMCID: PMC5399573
Related URLs:
URI: https://repository.cshl.edu/id/eprint/34471

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