The certainty of a few good reactions

Moorhouse, AD, Homer, JA, Moses, JE (August 2023) The certainty of a few good reactions. Chem, 9 (8). pp. 2063-2077. ISSN 2451-9308

DOI: 10.1016/j.chempr.2023.03.017

Abstract

The impact of click chemistry was recently recognized with the 2022 Nobel Prize in Chemistry. The breadth of areas where click chemistry has accelerated discovery is extensive. In one of the most written-about subjects in Chemistry over recent years, this short perspective zones in on a small fragment of what we consider to be some of the most critical developments in synthetic chemistry, which have expanded access to the click chemistry toolbox. In addition, we touch upon areas within medicinal chemistry and novel approaches to drug discovery enabled by click chemistry, where we believe there is untapped potential for biological functions to be found and exploited.

Item Type: Paper
Subjects: chemistry > techniques > click chemistry
CSHL Authors:
Communities: CSHL labs > Moses lab
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: 10 August 2023
Date Deposited: 12 Oct 2023 19:38
Last Modified: 12 Oct 2023 19:40
Related URLs:
URI: https://repository.cshl.edu/id/eprint/41213

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