Sulfur fluoride exchange

Homer, JA, Xu, L, Kayambu, N, Zheng, Q, Choi, EJ, Kim, BM, Sharpless, KB, Zuilhof, H, Dong, J, Moses, JE (December 2023) Sulfur fluoride exchange. Nature Reviews Methods Primers, 3 (1). ISSN 2662-8449 (In Press)

DOI: 10.1038/s43586-023-00241-y


Click chemistry is a conceptual strategy to rapidly synthesize and discover functional molecules. Sulfur fluoride exchange (SuFEx) is a click reaction that has revolutionized multiple research fields. In this Primer, we delve into the essential elements of SuFEx operation, catalysis and SuFExable connective hubs. We also explore the cutting-edge applications of SuFEx in drug development, polymer science and biochemistry. Additionally, we examine the potential limitations and promising prospects for this versatile click reaction.

Item Type: Paper
Subjects: chemistry > techniques > click chemistry > Accelerated SuFEx Click Chemistry
chemistry > techniques > click chemistry
CSHL Authors:
Communities: CSHL labs > Moses lab
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: 1 December 2023
Date Deposited: 12 Oct 2023 16:11
Last Modified: 12 Oct 2023 16:11
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