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Paper

Carnero, A., Hudson, J. D., Hannon, G. J., Beach, D. H. (2000) Loss-of-function genetics in mammalian cells: The p53 tumor suppressor model. Nucleic Acids Research, 28 (11). pp. 2234-2241. ISSN 03051048 (ISSN)

Hammond, S. M., Bernstein, E., Beach, D., Hannon, G. J. (2000) An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature, 404 (6775). pp. 293-296. ISSN 00280836 (ISSN)

Wang, J., Hannon, G. J., Beach, D. H. (2000) Risky immortalization by telomerase. Nature, 405 (6788). pp. 755-756. ISSN 00280836 (ISSN)

Hannon, G. J., Sun, P., Carnero, A., Xie, L. Y., Maestro, R., Conklin, D. S., Beach, D. (February 1999) MaRX: an approach to genetics in mammalian cells. Science, 283 (5405). pp. 1129-30. ISSN 0036-8075

Hudson, J. D., Shoaibi, M. A., Maestro, R., Carnero, A., Hannon, G. J., Beach, D. H. (1999) A proinflammatory cytokine inhibits p53 tumor suppressor activity. Journal of Experimental Medicine, 190 (10). pp. 1375-1382. ISSN 00221007 (ISSN)

Sun, P., Dong, P., Dai, K., Hannon, G. J., Beach, D. (December 1998) p53-independent role of MDM2 in TGF-beta1 resistance. Science, 282 (5397). pp. 2270-2. ISSN 0036-8075 (Print)

Wang, J., Xie, L. Y., Allan, S., Beach, D., Hannon, G. J. (1998) Myc activates telomerase. Genes and Development, 12 (12). pp. 1769-1774. ISSN 08909369 (ISSN)

Connolly, T., Caligiuri, M., Beach, D. (June 1997) The Cdc2 protein kinase controls Cdc10/Sct1 complex formation. Molecular Biology of the Cell, 8 (6). pp. 1105-15. ISSN 1059-1524 (Print)

Caligiuri, M., Connolly, T., Beach, D. (June 1997) Ran1 functions to control the Cdc10/Sct1 complex through Puc1. Molecular Biology of the Cell, 8 (6). pp. 1117-28. ISSN 1059-1524 (Print)

Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., Lowe, S. W. (March 1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 88 (5). pp. 593-602. ISSN 0092-8674 (Print)

Alcorta, D. A., Xiong, Y., Phelps, D., Hannon, G., Beach, D., Barrett, J. C. (November 1996) Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 13742-13747. ISSN 00278424 (ISSN)

Okamoto, K., Kamibayashi, C., Serrano, M., Prives, C., Mumby, M. C., Beach, D. (November 1996) p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A. Molecular and Cellular Biology, 16 (11). pp. 6593-602. ISSN 0270-7306

Casso, D., Beach, D. (October 1996) A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet, 252 (5). pp. 518-29. ISSN 0026-8925 (Print)

Galaktionov, K., Chen, X., Beach, D. (August 1996) Cdc25 cell-cycle phosphatase as a target of c-myc. Nature, 382 (6591). pp. 511-7. ISSN 0028-0836 (Print)

Lundgren, K., Allan, S., Urushiyama, S., Tani, T., Ohshima, Y., Frendewey, D., Beach, D. (July 1996) A connection between pre-mRNA splicing and the cell cycle in fission yeast: cdc28+ is allelic with prp8+ and encodes an RNA-dependent ATPase/helicase. Molecular Biology of the Cell, 7 (7). pp. 1083-94. ISSN 1059-1524

Serrano, M., Lee, H., Chin, L., Cordon-Cardo, C., Beach, D., DePinho, R. A. (April 1996) Role of the INK4a locus in tumor suppression and cell mortality. Cell, 85 (1). pp. 27-37. ISSN 0092-8674 (Print)

Nefsky, B., Beach, D. (March 1996) Pub1 acts as an E6-AP-like protein ubiquitiin ligase in the degradation of cdc25. Embo J, 15 (6). pp. 1301-12. ISSN 0261-4189 (Print)

Demetrick, D. J., Zhang, H., Beach, D. H. (1996) Chromosomal mapping of the genes for the human CDK2/cyclin A-associated proteins p19 (SKP1A and SKP1B) and p45 (SKP2). Cytogenet Cell Genet, 73 (1-2). pp. 104-7. ISSN 0301-0171 (Print)

Demetrick, D. J., Zhang, H., Beach, D. H. (1996) Chromosomal mapping of the human genes CKS1 to 8q21 and CKS2 to 9q22. Cytogenet Cell Genet, 73 (3). pp. 250-4. ISSN 0301-0171 (Print)

Terry, L. A., Boyd, J., Alcorta, D., Lyon, T., Solomon, G., Hannon, G., Berchuck, A., Beach, D., Barrett, J. C. (1996) Mutational analysis of the p21/WAF1/CIP1/SDI1 coding region in human tumor cell lines. Molecular Carcinogenesis, 16 (4). pp. 221-228. ISSN 08991987 (ISSN)

Li, Rong, Hannon, G. J., Beach, D., Stillman, B. (1996) Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage. Current Biology, 6 (2). pp. 189-199. ISSN 09609822 (ISSN)

Davey, S., Beach, D. (October 1995) RACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutation. Mol Biol Cell, 6 (10). pp. 1411-21. ISSN 1059-1524 (Print)

Zhang, H., Kobayashi, R., Galaktionov, K., Beach, D. (September 1995) p19Skp1 and p45Skp2 are essential elements of the cyclin A-CDK2 S phase kinase. Cell, 82 (6). pp. 915-25. ISSN 0092-8674 (Print)

Galaktionov, K., Lee, A. K., Eckstein, J., Draetta, G., Meckler, J., Loda, M., Beach, D. (September 1995) CDC25 phosphatases as potential human oncogenes. Science, 269 (5230). pp. 1575-7. ISSN 0036-8075 (Print)

Conklin, D. S., Galaktionov, K., Beach, D. (August 1995) 14-3-3 proteins associate with cdc25 phosphatases. Proc Natl Acad Sci U S A, 92 (17). pp. 7892-6. ISSN 0027-8424 (Print)

Galaktionov, K., Jessus, C., Beach, D. (May 1995) Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation. Genes Dev, 9 (9). pp. 1046-58. ISSN 0890-9369 (Print)

Serrano, M., Gomez-Lahoz, E., DePinho, R. A., Beach, D., Bar-Sagi, D. (January 1995) Inhibition of ras-induced proliferation and cellular transformation by p16INK4. Science, 267 (5195). pp. 249-52. ISSN 0036-8075 (Print)

Demetrick, D. J., Matsumoto, S., Hannon, G. J., Okamoto, K., Xiong, Y., Zhang, H., Beach, D. H. (1995) Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3). Cytogenetics and Cell Genetics, 69 (3-4). pp. 190-192. ISSN 03010171 (ISSN)

Quelle, D. E., Ashmun, R. A., Hannon, G. J., Rehberger, P. A., Trono, D., Richter, K. H., Walker, C., Beach, D., Sherr, C. J., Serrano, M. (1995) Cloning and characterization of murine p16(INK4a) and p15(INK4b) genes. Oncogene, 11 (4). pp. 635-645. ISSN 09509232 (ISSN)

Halevy, O., Novitch, B. G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., Beach, D., Lassar, A. B. (1995) Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science, 267 (5200). pp. 1018-1021. ISSN 00368075 (ISSN)

Orlow, I., Lacombe, L., Hannon, G. J., Serrano, M., Pellicer, I., Dalbagni, G., Reuter, V. E., Zhang, Z. F., Beach, D., Cordon-Cardo, C. (1995) Deletion of the p16 and p15 genes in human bladder tumors. Journal of the National Cancer Institute, 87 (20). pp. 1524-1529. ISSN 00278874 (ISSN)

Ranade, K., Hussussian, C. J., Sikorski, R. S., Varmus, H. E., Goldstein, A. M., Tucker, M. A., Serrano, M., Hannon, G. J., Beach, D., Dracopoli, N. C. (1995) Mutations associated with familial melanoma impair p16(INK4) function. Nature Genetics, 10 (1). pp. 114-116. ISSN 10614036 (ISSN)

Okamoto, A., Hussain, S. P., Hagiwara, K., Spillare, E. A., Rusin, M. R., Demetrick, D. J., Serrano, M., Hannon, G. J., Shiseki, M., Zariwala, M., Xiong, Y., Beach, D. H., Yokota, J., Harris, C. C. (1995) Mutations in the p16(INK4)/MTS1/CDKN2, p15(INK4B)/MTS2, and p18 genes in primary and metastatic lung cancer. Cancer Research, 55 (7). pp. 1448-1451. ISSN 00085472 (ISSN)

Bruarolas, J., Chandrasekaran, C., Gordon, J. I., Beach, D., Jacks, T., Hannon, G. J. (1995) Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature, 377 (6549). pp. 552-557. ISSN 00280836 (ISSN)

Okuda, T., Valentine, M. B., Shurtleff, S. A., Hulshof, M. G., Komuro, H., Raimondi, S. C., Pui, C. H., Beach, D., Sherr, C. J., Look, A. T., Downing, J. R. (November 1994) Frequent Deletion of Ink4a/Mts1 in Pediatric Acute Lymphoblastic-Leukemia. Blood, 84 (10). A298-A298. ISSN 0006-4971

Okamoto, A., Demetrick, D. J., Spillare, E. A., Hagiwara, K., Hussain, S. P., Bennett, W. P., Forrester, K., Gerwin, B., Serrano, M., Beach, D. H., Harris, C. C. (November 1994) Mutations and altered expression of p16INK4 in human cancer. Proceedings of the National Academy of Sciences of the United States of America, 91 (23). pp. 11045-11049. ISSN 0027-8424

Okamoto, K., Beach, D. (October 1994) Cyclin G is a transcriptional target of the p53 tumor suppressor protein. Embo J, 13 (20). pp. 4816-22. ISSN 0261-4189 (Print)

Philipp, A., Schneider, A., Vasrik, I., Finke, K., Xiong, Y., Beach, D., Alitalo, K., Eilers, M. (June 1994) Repression of Cyclin D1 - a Novel Function of Myc. Molecular and Cellular Biology, 14 (6). pp. 4032-4043. ISSN 0270-7306

Beach, D., Serrano, M., Hannon, G. J. (February 1994) P16(Ink4) - an Specific Inhibitor of the Cdk4/Cyclin-D Kinase. Journal of Cellular Biochemistry, Supp (18C). p. 161. ISSN 0730-2312

Hofmann, J. F., Beach, D. (January 1994) cdt1 is an essential target of the Cdc10/Sct1 transcription factor: requirement for DNA replication and inhibition of mitosis. Embo J, 13 (2). pp. 425-34. ISSN 0261-4189 (Print)

Connolly, T., Beach, D. (January 1994) Interaction between the Cig1 and Cig2 B-type cyclins in the fission yeast cell cycle. Mol Cell Biol, 14 (1). pp. 768-76. ISSN 0270-7306 (Print)

Demetrick, D. J., Zhang, H., Beach, D. H. (1994) Chromosomal mapping of human CDK2, CDK4, and CDK5 cell cycle kinase genes. Cytogenet Cell Genet, 66 (1). pp. 72-4. ISSN 0301-0171 (Print)

Feilotter, H. E., Hannon, G. J., Ruddell, C. J., Beach, D. (1994) Construction of an improved host strain for two hybrid screening. Nucleic Acids Research, 22 (8). pp. 1502-1503. ISSN 03051048 (ISSN)

Li, R., Waga, S., Hannon, G. J., Beach, D., Stillman, B. (1994) Differential effects by the p21 CDK inhibitor on PCNA-dependent DNA replication and repair. Nature, 371 (6497). pp. 534-537. ISSN 00280836 (ISSN)

Hannon, G. J., Casso, D., Beach, D. (1994) KAP: A dual specificity phosphatase that interacts with cyclin-dependent kinases. Proceedings of the National Academy of Sciences of the United States of America, 91 (5). pp. 1731-1735. ISSN 00278424 (ISSN)

Hannon, G. J., Beach, D. (1994) p15(INK4B) is a potential effector of TGF-β-induced cell cycle arrest. Nature, 371 (6494). pp. 257-261. ISSN 00280836 (ISSN)

Waga, S., Hannon, G. J., Beach, D., Stillman, B. (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature, 369 (6481). pp. 574-578. ISSN 00280836 (ISSN)

Zhang, H., Hannon, G. J., Casso, D., Beach, D. (1994) p21 is a component of active cell cycle kinases. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 21-29. ISSN 00917451 (ISSN)

Zhang, H., Hannon, G. J., Beach, D. (1994) p21-Containing cyclin kinases exist in both active and inactive states. Genes and Development, 8 (15). pp. 1750-1758. ISSN 08909369 (ISSN)

Demetrick, D. J., Beach, D. H. (October 1993) Chromosome mapping of human CDC25A and CDC25B phosphatases. Genomics, 18 (1). pp. 144-7. ISSN 0888-7543 (Print)

Zhang, H., Xiong, Y., Beach, D. (September 1993) Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes. Mol Biol Cell, 4 (9). pp. 897-906. ISSN 1059-1524 (Print)

Xiong, Y., Zhang, H., Beach, D. (August 1993) Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev, 7 (8). pp. 1572-83. ISSN 0890-9369 (Print)

Walworth, N., Davey, S., Beach, D. (May 1993) Fission yeast chk1 protein kinase links the rad checkpoint pathway to cdc2. Nature, 363 (6427). pp. 368-71. ISSN 0028-0836 (Print)

Cottarel, G., Beach, D., Deuschle, U. (May 1993) 2 New Multipurpose Multicopy Schizosaccharomyces-Pombe Shuttle Vectors, Psp1 and Psp2. Current Genetics, 23 (5-6). pp. 547-548. ISSN 0172-8083

Samejima, I., Matsumoto, T., Nakaseko, Y., Beach, D., Yanagida, M. (May 1993) Identification of 7 New Cut Genes Involved in Schizosaccharomyces-Pombe Mitosis. Journal of Cell Science, 105. pp. 135-143. ISSN 0021-95331477-9137

Mizukami, T., Chang, W. I., Garkavtsev, I., Kaplan, N., Lombardi, D., Matsumoto, T., Niwa, O., Kounosu, A., Yanagida, M., Marr, T. G., Beach, D. (April 1993) A 13-Kb Resolution Cosmid Map of the 14-Mb Fission Yeast Genome by Nonrandom Sequence-Tagged Site Mapping. Cell, 73 (1). pp. 121-132. ISSN 0092-8674

Molz, L., Beach, D. (April 1993) Characterization of the fission yeast mcs2 cyclin and its associated protein kinase activity. Embo J, 12 (4). pp. 1723-32. ISSN 0261-4189 (Print)

Matsumoto, T., Beach, D. (March 1993) Interaction of the pim1/spi1 mitotic checkpoint with a protein phosphatase. Mol Biol Cell, 4 (3). pp. 337-45. ISSN 1059-1524 (Print)

Caligiuri, M., Beach, D. (February 1993) Sct1 functions in partnership with Cdc10 in a transcription complex that activates cell cycle START and inhibits differentiation. Cell, 72 (4). pp. 607-19. ISSN 0092-8674 (Print)

Hannon, G. J., Demetrick, D., Beach, D. (1993) Isolation of the Rb-related p130 through its interaction with CDK2 and cyclins. Genes and Development, 7 (12 A). pp. 2378-2391. ISSN 08909369 (ISSN)

Serrano, M., Hannon, G. J., Beach, D. (1993) A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4. Nature, 366 (6456). pp. 704-707. ISSN 00280836 (ISSN)

Xiong, Y., Hannon, G. J., Zhang, H., Casso, D., Kobayashi, R., Beach, D. (1993) p21 is a universal inhibitor of cyclin kinases. Nature, 366 (6456). pp. 701-704. ISSN 00280836 (ISSN)

Xiong, Y., Zhang, H., Beach, D. (October 1992) D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell, 71 (3). pp. 505-14. ISSN 0092-8674 (Print)0092-8674 (Linking)

Won, K. A., Xiong, Y., Beach, D., Gilman, M. Z. (October 1992) Growth-regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc Natl Acad Sci U S A, 89 (20). pp. 9910-4. ISSN 0027-8424 (Print)0027-8424 (Linking)

Xiong, Y., Menninger, J., Beach, D., Ward, D. C. (July 1992) Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins. Genomics, 13 (3). pp. 575-84. ISSN 0888-7543 (Print)0888-7543 (Linking)

Baratte, B., Meijer, L., Galaktionov, K., Beach, D. (May 1992) Screening for antimitotic compounds using the cdc25 tyrosine phosphatase, an activator of the mitosis-inducing p34cdc2/cyclin Bcdc13 protein kinase. Anticancer Research, 12 (3). pp. 873-880. ISSN 0250-7005

Bischoff, J. R., Casso, D., Beach, D. (April 1992) Human p53 inhibits growth in Schizosaccharomyces pombe. Mol Cell Biol, 12 (4). pp. 1405-11. ISSN 0270-7306 (Print)0270-7306 (Linking)

Jessus, C., Beach, D. (January 1992) Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B. Cell, 68 (2). pp. 323-32. ISSN 0092-8674 (Print)0092-8674 (Linking)

Beach, D. (January 1992) Cell Cycle Control. Faseb Journal, 6 (1). A126-A126. ISSN 0892-6638

Beach, D. (1992) Genetic Dissection of Cell Cycle Dependency. Harvey Lectures, 86. pp. 19-31. ISSN 0073-0874

Galaktionov, K., Beach, D. (December 1991) Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: evidence for multiple roles of mitotic cyclins. Cell, 67 (6). pp. 1181-94. ISSN 0092-8674 (Print)0092-8674 (Linking)

Xiong, Y., Beach, D. (December 1991) Population explosion in the cyclin family. Curr Biol, 1 (6). pp. 362-4. ISSN 0960-9822 (Print)0960-9822 (Linking)

Jans, D. A., Ackermann, M. J., Bischoff, J. R., Beach, D. H., Peters, R. (December 1991) p34cdc2-mediated phosphorylation at T124 inhibits nuclear import of SV-40 T antigen proteins. Journal of Cell Biology, 115 (5). pp. 1203-1212. ISSN 0021-9525

Giordano, A., Lee, J. H., Scheppler, J. A., Herrmann, C., Harlow, E., Deuschle, U., Beach, D., Franza, B. R. (September 1991) Cell cycle regulation of histone H1 kinase activity associated with the adenoviral protein E1A. Science, 253 (5025). pp. 1271-5. ISSN 0036-8075 (Print)0036-8075 (Linking)

Roth, S. Y., Collini, M. P., Draetta, G., Beach, D., Allis, C. D. (August 1991) A cdc2-like kinase phosphorylates histone H1 in the amitotic macronucleus of Tetrahymena. EMBO J, 10 (8). pp. 2069-75. ISSN 0261-4189 (Print)0261-4189 (Linking)

Matsumoto, T., Beach, D. (July 1991) Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase. Cell, 66 (2). pp. 347-60. ISSN 0092-8674 (Print)0092-8674 (Linking)

Xiong, Y., Connolly, T., Futcher, B., Beach, D. (May 1991) Human D-type cyclin. Cell, 65 (4). pp. 691-9. ISSN 0092-8674 (Print)0092-8674 (Linking)

Luscher, B., Brizuela, L., Beach, D., Eisenman, R. N. (April 1991) A role for the p34cdc2 kinase and phosphatases in the regulation of phosphorylation and disassembly of lamin B2 during the cell cycle. EMBO J, 10 (4). pp. 865-75. ISSN 0261-4189 (Print)0261-4189 (Linking)

Lundgren, K., Walworth, N., Booher, R., Dembski, M., Kirschner, M., Beach, D. (March 1991) mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2. Cell, 64 (6). pp. 1111-22. ISSN 0092-8674 (Print)0092-8674 (Linking)

Dessev, G., Iovcheva-Dessev, C., Bischoff, J. R., Beach, D., Goldman, R. (February 1991) A complex containing p34cdc2 and cyclin B phosphorylates the nuclear lamin and disassembles nuclei of clam oocytes in vitro. J Cell Biol, 112 (4). pp. 523-33. ISSN 0021-9525 (Print)0021-9525 (Linking)

Bischoff, J. R., Casso, D., Beach, D. (1991) Expression of Human P53 in Fission Yeast. Journal of Cellular Biochemistry, 47 (Suppl ). p. 65.

Connolly, T., Molz, L., Futcher, B., Beach, D. (1991) Fission Yeast Cyclins. Journal of Cellular Biochemistry, 47 (Suppl ). p. 92.

Galaktionov, K., Beach, D. (1991) Human Homolog of the Fission Yeast Cdc25 Gene Is Essential for Mitosis. Journal of Cell Biology, 115 (3 PART). 424A.

Lundgren, K., Beach, D. (1991) Mik1 and Wee1 Mitotic Inhibitors Cooperate in Cdc2 Tyrosine Phosphorylation. Journal of Cell Biology, 115 (3 PART). 423A.

Matsumoto, T., Beach, D. (1991) Spi1 GTPase interacts with RCC1 to maintain interdependency of cell cycle events. Princess Takamatsu Symp, 22. pp. 145-52.

Matsumoto, T., Beach, D. (1991) The spil GTPase interacts with RCCl in cell cycle dependency. Cold Spring Harb Symp Quant Biol, 56. pp. 385-98. ISSN 0091-7451 (Print)0091-7451 (Linking)

Alfa, C. E., Ducommun, B., Beach, D., Hyams, J. S. (October 1990) Distinct nuclear and spindle pole body population of cyclin-cdc2 in fission yeast. Nature, 347 (6294). pp. 680-2. ISSN 0028-0836 (Print)0028-0836 (Linking)

Chou, Y. H., Bischoff, J. R., Beach, D., Goldman, R. D. (September 1990) Intermediate Filament Reorganization during Mitosis Is Mediated by P34cdc2 Phosphorylation of Vimentin. Cell, 62 (6). pp. 1063-1071. ISSN 0092-8674

Ducommun, B., Tollon, Y., Gares, M., Beach, D., Wright, M. (August 1990) Cell cycle regulation of p34cdc2 kinase activity in Physarum polycephalum. J Cell Sci, 96 ((Pt 4)). pp. 683-9. ISSN 0021-9533 (Print)0021-9533 (Linking)

Jessus, C., Ducommun, B., Beach, D. (June 1990) Direct activation of cdc2 with phosphatase: identification of p13suc1-sensitive and insensitive steps. FEBS Lett, 266 (1-2). pp. 4-8. ISSN 0014-5793 (Print)0014-5793 (Linking)

Bischoff, J. R., Friedman, P. N., Marshak, D. R., Prives, C., Beach, D. (June 1990) Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. Proc Natl Acad Sci U S A, 87 (12). pp. 4766-70. ISSN 0027-8424 (Print)0027-8424 (Linking)

Ducommun, B., Beach, D. (May 1990) A versatile microtiter assay for the universal cdc2 cell cycle regulator. Anal Biochem, 187 (1). pp. 94-7. ISSN 0003-2697 (Print)0003-2697 (Linking)

Ducommun, B., Draetta, G., Young, P., Beach, D. (February 1990) Fission yeast cdc25 is a cell-cycle regulated protein. Biochem Biophys Res Commun, 167 (1). pp. 301-9. ISSN 0006-291X (Print)0006-291X (Linking)

Pondaven, P., Meijer, L., Beach, D. (January 1990) Activation of M-phase-specific histone H1 kinase by modification of the phosphorylation of its p34cdc2 and cyclin components. Genes Dev, 4 (1). pp. 9-17. ISSN 0890-9369 (Print)0890-9369 (Linking)

Beach, D. (1990) Genetic dissection of cell cycle dependency. Harvey Lect, 86. pp. 19-31. ISSN 0073-0874 (Print)0073-0874 (Linking)

Lundgren, K., Dembski, M., Beach, D. (1990) Identification and Characterization of a Novel Mitotic Inhibitory Kinase in Schizosaccharomyces-Pombe. Journal of Cell Biology, 111 (5 PART). 93A.

Beach, D., Draetta, G. (1990) Regulation of the Cell Cycle by Cdc2 and Its Associated Cyclins. Journal of Cellular Biochemistry, 44 (S14E). p. 132.

McVey, D., Brizuela, L., Mohr, I., Marshak, D. R., Gluzman, Y., Beach, D. (October 1989) Phosphorylation of large tumour antigen by cdc2 stimulates SV40 DNA replication. Nature, 341 (6242). pp. 503-7. ISSN 1476-4687

Giordano, A., Whyte, P., Harlow, E., Franza, B. R., Beach, D., Draetta, G. (September 1989) A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells. Cell, 58 (5). pp. 981-90. ISSN 0092-8674

Booher, R. N., Alfa, C. E., Hyams, J. S., Beach, D. H. (August 1989) The fission yeast cdc2/cdc13/suc1 protein kinase: regulation of catalytic activity and nuclear localization. Cell, 58 (3). pp. 485-97. ISSN 1097-4172

Meijer, L., Arion, D., Golsteyn, R., Pines, J., Brizuela, L., Hunt, T., Beach, D. (August 1989) Cyclin Is a Component of the Sea-Urchin Egg M-Phase Specific Histone H-1 Kinase. Embo Journal, 8 (8). pp. 2275-2282. ISSN 0261-4189

Molz, L., Booher, R., Young, P., Beach, D. (August 1989) cdc2 and the regulation of mitosis: six interacting mcs genes. Genetics, 122 (4). pp. 773-82. ISSN 0016-6731

Morla, A. O., Draetta, G., Beach, D., Wang, J. Y. J. (July 1989) Reversible Tyrosine Phosphorylation of Cdc2 - Dephosphorylation Accompanies Activation During Entry into Mitosis. Cell, 58 (1). pp. 193-203. ISSN 0092-8674

Booher, R., Beach, D. (June 1989) Involvement of a type 1 protein phosphatase encoded by bws1+ in fission yeast mitotic control. Cell, 57 (6). pp. 1009-16. ISSN 1097-4172

Brizuela, L., Draetta, G., Beach, D. (June 1989) Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit. Proc Natl Acad Sci U S A, 86 (12). pp. 4362-6. ISSN 1091-6490

Riabowol, K., Draetta, G., Brizuela, L., Vandre, D., Beach, D. (May 1989) The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells. Cell, 57 (3). pp. 393-401. ISSN 0092-8674

Draetta, G., Luca, F., Westendorf, J., Brizuela, L., Ruderman, J., Beach, D. (March 1989) Cdc2 protein kinase is complexed with both cyclin A and B: evidence for proteolytic inactivation of MPF. Cell, 56 (5). pp. 829-38. ISSN 0092-8674

Draetta, G., Beach, D. (February 1989) The mammalian cdc2 protein kinase: mechanisms of regulation during the cell cycle. J Cell Sci Suppl, 92 (2, Sup). pp. 21-7. ISSN ‎0021-9533

Alfa, C. E., Booher, R., Beach, D., Hyams, J. S. (1989) Fission Yeast Cyclin - Subcellular-Localization and Cell-Cycle Regulation. Journal of Cell Science , Supple (12). pp. 9-19. ISSN 0021-9533

Draetta, G., Piwnica-Worms, H., Morrison, D., Druker, B., Roberts, T., Beach, D. (December 1988) Human cdc2 protein kinase is a major cell-cycle regulated tyrosine kinase substrate. Nature, 336 (6201). pp. 738-44. ISSN 0028-0836

Solomon, M., Booher, R., Kirschner, M., Beach, D. (September 1988) Cyclin in Fission Yeast. Cell, 54 (6). pp. 738-739. ISSN 0092-8674

Potashkin, J. A., Beach, D. H. (September 1988) Multiple phosphorylated forms of the product of the fission yeast cell division cycle gene cdc2+. Curr Genet, 14 (3). pp. 235-40. ISSN 0172-8083

Dunphy, W. G., Brizuela, L., Beach, D., Newport, J. (July 1988) The Xenopus Cdc2 Protein Is a Component of Mpf, a Cytoplasmic Regulator of Mitosis. Cell, 54 (3). pp. 423-431. ISSN 0092-8674

Draetta, G., Beach, D. (July 1988) Activation of cdc2 protein kinase during mitosis in human cells: cell cycle-dependent phosphorylation and subunit rearrangement. Cell, 54 (1). pp. 17-26. ISSN 0092-8674

Draetta, G., Brizuela, L., Moran, B., Beach, D. (June 1988) Regulation of the vertebrate cell cycle by the cdc2 protein kinase. Cold Spring Harb Symp Quant Biol, 53 Pt . pp. 195-201. ISSN 0091-7451

Draetta, G., Beach, D., Moran, E. (June 1988) Synthesis of p34, the mammalian homolog of the yeast cdc2+/CDC28 protein kinase, is stimulated during adenovirus-induced proliferation of primary baby rat kidney cells. Oncogene, 2 (6). pp. 553-7. ISSN 0950-9232

Kelly, M., Burke, J., Smith, M., Klar, A., Beach, D. (May 1988) Four mating-type genes control sexual differentiation in the fission yeast. Embo J, 7 (5). pp. 1537-47. ISSN 0261-4189

Draetta, G., Brizuela, L., Beach, D. (January 1988) p34, a protein kinase involved in cell cycle regulation in eukaryotic cells. Adv Exp Med Biol, 231. pp. 453-7. ISSN 0065-2598

Book Section

Bischoff, J. R., Casso, D., Beach, D. (1991) A Yeast System to Study Human P53. In: Origins of human cancer: a comprehensive review. Cold Spring Harbor Laboratory Press, Plainview, N. Y., pp. 51-63. ISBN 0879694041

This list was generated on Mon Dec 9 08:37:01 2024 EST.