Items where Subject is "bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > oncogene"

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Number of items at this level: 146.

A

Abate, C., Baker, S. J., Lees-Miller, S. P., Anderson, C. W., Marshak, D. R., Curran, T. (1993) Dimerization and DNA-Binding Alter Phosphorylation of Fos and Jun. Proc Natl Acad Sci U S A, 90 (14). pp. 6766-6770. ISSN 0027-8424

Atwal, G. S., Kirchhoff, T., Bond, E. E., Montagna, M., Menin, C., Bertorelle, R., Scaini, M. C., Bartel, F., Böhnke, A., Pempe, C., Gradhand, E., Hauptmann, S., Offit, K., Levine, A. J., Bond, G. L. (2009) Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene. Proc Natl Acad Sci U S A, 106 (25). pp. 10236-10241. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

B

Bargonetti, J., Manfredi, J. J., Chen, X. B., Marshak, D. R., Prives, C. (1993) A Proteolytic Fragment from the Central Region of P53 Has Marked Sequence-Specific DNA-Binding Activity When Generated from Wild-Type but Not from Oncogenic Mutant P53-Protein. Genes Dev, 7 (12B). pp. 2565-2574. ISSN 0890-9369

Barker, D., McCoy, M., Weinberg, R., Goldfarb, M., Wigler, M. H., Burt, R., Gardner, E., White, R. (1983) A test of the role of two oncogenes in inherited predisposition to colon cancer. Mol Biol Med, 1 (2). pp. 199-206. ISSN 0735-1313 (Print)

Ben-Hur, V., Denichenko, P., Siegfried, Z., Maimon, A., Krainer, A., Davidson, B., Karni, R. (2013) S6K1 Alternative Splicing Modulates Its Oncogenic Activity and Regulates mTORC1. Cell Reports, 3 (1). pp. 103-115. ISSN 22111247

Birchmeier, C., Birnbaum, D., Waitches, G., Fasano, O., Wigler, M. H. (1986) Characterization of an activated human ros gene. Molecular & Cellular Biology, 6 (9). pp. 3109-3116.

Birchmeier, C., Young, D., Wigler, M. H. (1986) Characterization of two new human oncogenes. Cold Spring Harbor Symposia on Quantitative Biology, 51 (2). pp. 993-1000. ISSN 00917451 (ISSN)

Boettner, B., Van Aelst, L. (2002) The RASputin effect. Genes & Development, 16 (16). pp. 2033-2038. ISSN 0890-9369

Boivin, B., Chaudhary, F., Dickinson, B. C., Haque, A., Pero, S. C., Chang, C. J., Tonks, N. K. (2013) Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein mediated mammary epithelial cell motility. Journal of Biological Chemistry, 288 (52). pp. 36926-36935. ISSN 00219258 (ISSN)

Buchkovich, K., Dyson, N., Whyte, P., Harlow, E. (1990) Cellular proteins that are targets for transformation by DNA tumour viruses. Ciba Found Symp, 150. 262-71; discussion 271. ISSN 0300-5208 (Print)0300-5208 (Linking)

C

Cai, C. L., Rajaram, M., Zhou, X., Liu, Q., Marchica, J., Li, J. Y., Powers, R. S. (2012) Activation of multiple cancer pathways and tumor maintenance function of the 3q amplified oncogene FNDC3B. Cell Cycle, 11 (9). pp. 1773-1781. ISSN 1538-4101

Catanzaro, J. M., Sheshadri, N., Pan, J. A., Sun, Y., Shi, C., Li, J., Powers, R. S., Crawford, H. C., Zong, W. X. (2014) Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4. Nature Communications, 5. p. 3729. ISSN 20411723

Chatterjee, S., Seifried, L., Feigin, M. E., Gibbons, D. L., Scuoppo, C., Lin, W., Rizvi, Z. H., Lind, E., Dissanayake, D., Kurie, J., Ohashi, P., Muthuswamy, S. K. (2012) Dysregulation of Cell Polarity Proteins Synergize with Oncogenes or the Microenvironment to Induce Invasive Behavior in Epithelial Cells. PLoS ONE, 7 (4). ISSN 1932-6203

Chi, P., Chen, Y., Zhang, L., Guo, X., Wongvipat, J., Shamu, T., Fletcher, J. A., Dewell, S., Maki, R. G., Zheng, D., Antonescu, C. R., Allis, C. D., Sawyers, C. L. (2010) ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours. Nature, 467 (7317). pp. 849-53. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Cockcroft, S., Bar-Sagi, D. (1990) Effect of H-ras proteins on the activity of polyphosphoinositide phospholipase C in HL60 membranes. Cell Signal, 2 (3). pp. 227-34. ISSN 0898-6568 (Print)0898-6568 (Linking)

D

Das, S., Anczuków, O., Akerman, M., Krainer, A. R (2012) Oncogenic Splicing Factor SRSF1 Is a Critical Transcriptional Target of MYC. Cell Reports, 1 (2). pp. 110-117. ISSN 2211-1247

Das, S., Fregoso, O. I., Krainer, A. R. (2013) A new path to oncogene-induced senescence: At the cross-roads of splicing and translation. Cell Cycle, 12 (10). ISSN 1551-4005 (Electronic)1551-4005 (Linking)

DeNicola, G. M., Karreth, F. A., Humpton, T. J., Gopinathan, A., Wei, C., Frese, K., Mangal, D., Yu, K. H., Yeo, C. J., Calhoun, E. S., Scrimieri, F., Winter, J. M., Hruban, R. H., Iacobuzio-Donahue, C., Kern, S. E., Blair, I. A., Tuveson, D. A. (2011) Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis. Nature, 475 (7354). pp. 106-9. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Duelli, D. M., Lazebnik, Y. A. (2000) Primary cells suppress oncogene-dependent apoptosis. Nature Cell Biology, 2 (11). pp. 859-862. ISSN 1465-7392

Dyson, N., Buchkovich, K., Hu, Q., Harlow, E. (1990) Cellular Targets for Transformation by DNA Tumor Viruses. Journal of Cellular Biochemistry, 44 (S14C). p. 257.

Dyson, N., Guida, P., McCall, C., Harlow, E. (1992) Adenovirus E1A makes two distinct contacts with the retinoblastoma protein. J Virol, 66 (7). pp. 4606-11. ISSN 0022-538X (Print)0022-538X (Linking)

de Stanchina, E., McCurrach, M. E., Zindy, F., Shieh, S. Y., Ferbeyre, G., Samuelson, A. V., Prives, C., Roussel, M. F., Sherr, C. J., Lowe, S. W. (1998) E1A signaling to p53 involves the p19(ARF) tumor suppressor. Genes Dev, 12 (15). pp. 2434-42. ISSN 0890-9369 (Print)

E

Efrat, S., Fleischer, N., Hanahan, D. (1990) Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cells. Mol Cell Biol, 10 (4). pp. 1779-83. ISSN 0270-7306 (Print)0270-7306 (Linking)

Efrat, S., Linde, S., Kofod, H., Spector, D., Delannoy, M., Grant, S., Hanahan, D., Baekkeskov, S. (1988) Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proceedings of the National Academy of Sciences of the United States of America, 85 (23). pp. 9037-41. ISSN 0027-8424 (Print)0027-8424

Eifert, C., Powers, R. S. (2012) From cancer genomes to oncogenic drivers, tumour dependencies and therapeutic targets. Nat Rev Cancer, 12 (8). pp. 572-578. ISSN 1474-1768 (Electronic)1474-175X (Linking)

Errani, C., Zhang, L., Sung, Y. S., Hajdu, M., Singer, S., Maki, R. G., Healey, J. H., Antonescu, C. R. (2011) A novel WWTR1-CAMTA1 gene fusion is a consistent abnormality in epithelioid hemangioendothelioma of different anatomic sites. Genes Chromosomes Cancer, 50 (8). pp. 644-53. ISSN 1098-2264 (Electronic)1045-2257 (Linking)

F

Fasano, O., Birnbaum, D., Edlund, L., Fogh, J., Wigler, M. H. (1984) New human transforming genes detected by a tumorigenicity assay. Molecular & Cellular Biology, 4 (9). pp. 1695-1705.

Fasano, O., Taparowsky, E., Fiddes, J., Wigler, M. H., Goldfarb, M. (1983) Sequence and Structure of the Coding Regions of the Human H-Ras-1 Gene from T-24 Bladder Carcinoma Cells. Journal of Molecular & Applied Genetics, 2 (2). pp. 173-180. ISSN 0271-6801

Fearnhead, H. O., McCurrach, M. E., O'Neill, J., Zhang, K., Lowe, S. W., Lazebnik, Y. A. (1997) Oncogene-dependent apoptosis in extracts from drug-resistant cells. Genes Dev, 11 (10). pp. 1266-1276. ISSN 0890-9369

Fearnhead, H. O., Rodriguez, J., Govek, E. E., Guo, W., Kobayashi, R., Hannon, G., Lazebnik, Y. A. (1998) Oncogene-dependent apoptosis is mediated by caspase-9. Proc Natl Acad Sci U S A, 95 (23). pp. 13664-13669. ISSN 0027-8424

Feramisco, J., Sullivan, N., Kamata, T., Barsagi, D., Welch, W., Gross, M., Sweet, R., Rosenberg, M., Sathe, G., Fasano, O., Goldfarb, M., Wigler, M. H., Nitecki, D., Clark, R., Arnheim, N., McCormick, F. (1985) Microinjection of Ras Oncogene Proteins and Inhibitory Antibodies Specific for the Ras Oncogene Proteins into Living Normal and Transformed-Cells. Federation Proceedings, 44 (5). p. 1768. ISSN 0014-9446

Ferbeyre, G., De Stanchina, E., Lin, A. W., Querido, E., McCurrach, M. E., Hannon, G. J., Lowe, S. W. (2002) Oncogenic ras and p53 cooperate to induce cellular senescence. Molecular and Cellular Biology, 22 (10). pp. 3497-3508. ISSN 02707306 (ISSN)

Ferbeyre, G., de Stanchina, E., Querido, E., Baptiste, N., Prives, C., Lowe, S. W. (2000) PML is induced by oncogenic ras and promotes premature senescence. Genes & Development, 14 (16). pp. 2015-2027. ISSN 0890-9369

Field, J., Broek, D., Kataoka, T., Wigler, M. H. (1987) Guanine nucleotide activation of, and competition between, RAS proteins from Saccharomyces cerevisiae. Molecular & Cellular Biology, 7 (6). pp. 2128-2133.

Field, J., Nikawa, J., Broek, D., MacDonald, B., Rodgers, L., Wilson, I. A., Lerner, R. A., Wigler, M. H. (1988) Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method. Molecular & Cellular Biology, 8 (5). pp. 2159-65. ISSN 0270-7306

G

Galaktionov, K., Chen, X., Beach, D. (1996) Cdc25 cell-cycle phosphatase as a target of c-myc. Nature, 382 (6591). pp. 511-7. ISSN 0028-0836 (Print)

Galaktionov, K., Lee, A. K., Eckstein, J., Draetta, G., Meckler, J., Loda, M., Beach, D. (1995) CDC25 phosphatases as potential human oncogenes. Science, 269 (5230). pp. 1575-7. ISSN 0036-8075 (Print)

Garrels, J. I., Franza, B. R., Chang, C., Latter, G. (1990) Quantitative exploration of the REF52 protein database: cluster analysis reveals the major protein expression profiles in responses to growth regulation, serum stimulation, and viral transformation. Electrophoresis, 11 (12). pp. 1114-30. ISSN 0173-0835 (Print)0173-0835 (Linking)

Goldfarb, M., Shimizu, K., Perucho, M., Wigler, M. H. (1982) Isolation and Preliminary Characterization of a Human Transforming Gene from T24 Bladder-Carcinoma Cells. Nature, 296 (5856). pp. 404-409. ISSN 0028-0836

Guo, T., Zhang, L., Chang, N. E., Singer, S., Maki, R. G., Antonescu, C. R. (2011) Consistent MYC and FLT4 gene amplification in radiation-induced angiosarcoma but not in other radiation-associated atypical vascular lesions. Genes Chromosomes Cancer, 50 (1). pp. 25-33. ISSN 1098-2264 (Electronic)1045-2257 (Linking)

H

Hamaguchi, M., O'Connor, E. A., Chen, T., Parnell, L., McCombie, R. W., Wigler, M. H. (1998) Rapid isolation of cDNA by hybridization. Proceedings of the National Academy of Sciences of the United States of America, 95 (7). pp. 3764-9. ISSN 0027-8424

Harrison, M., Li, J., Degenhardt, Y., Hoey, T., Powers, S. (2004) Wip1-deficient mice are resistant to common cancer genes. Trends in Molecular Medicine, 10 (8). pp. 359-361. ISSN 1471-4914

Hu, Q. J., Bautista, C., Edwards, G. M., Defeo-Jones, D., Jones, R. E., Harlow, E. (1991) Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides. Mol Cell Biol, 11 (11). pp. 5792-9. ISSN 0270-7306 (Print)0270-7306 (Linking)

J

Janas, J. A., Van Aelst, L. (2011) Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Molecular and Cellular Biology, 31 (13). pp. 2552-2565. ISSN 0270-7306

K

Kannabiran, C., Morris, G. F., Mathews, M. B. (1999) Dual action of the adenovirus E1A 243R oncoprotein on the human proliferating cell nuclear antigen promoter: repression of transcriptional activation by p53. Oncogene, 18 (54). pp. 7825-33. ISSN 0950-9232 (Print)

Kaplan, S., Bar-Sagi, D. (1991) Association of p21ras with cellular polypeptides. J Biol Chem, 266 (28). pp. 18934-41. ISSN 0021-9258 (Print)0021-9258 (Linking)

Keyes, W. M. , Pecoraro, M., Aranda, V., Vernersson-Lindahl, E., Li, W., Vogel, H., Guo, X., Garcia, E. L., Michurina, T. V., Enikolopov, G. N., Muthuswamy, S. K., Mills, A. A. (2011) DeltaNp63alpha Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis. Cell Stem Cell, 8 (2). pp. 164-76. ISSN 1875-9777 (Electronic)

Khosravi-Far, R., White, M. A., Westwick, J. K., Solski, P. A., Chrzanowska-Wodnicka, M., Van Aelst, L., Wigler, M. H., Der, C. J. (1996) Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol Cell Biol, 16 (7). pp. 3923-33. ISSN 0270-7306 (Print)

Kolman, J. L., Taylor, N., Marshak, D. R., Miller, G. (1993) Serine-173 of the Epstein-Barr-Virus Zebra Protein Is Required for DNA-Binding and Is a Target for Casein Kinase-Ii Phosphorylation. Proc Natl Acad Sci U S A, 90 (21). pp. 10115-10119. ISSN 0027-8424

Krainer, A. R., Karni, R. (2006) Oncogenic activity of alternative splicing factors. Faseb Journal, 20 (4). A456-A456. ISSN 0892-6638

Kraus, V. B., Moran, E., Nevins, J. R. (1992) Promoter-Specific Transactivation by the Adenovirus-E1a12s Product Involves Separate E1a Domains. Molecular and Cellular Biology, 12 (10). pp. 4391-4399. ISSN 0270-7306

Kumar, S., Pena, L. A., Devellis, J. (1993) Cns Glial-Cells Express Neurotrophin Receptors Whose Levels Are Regulated by Ngf. Molecular Brain Research, 17 (1-2). pp. 163-168. ISSN 0169-328X

L

La Montagne, K. R., Flint, A. J., Franza, B. R., Pendergast, A. M., Tonks, N. K. (1998) Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo. Molecular and Cellular Biology, 18 (5). pp. 2965-2975. ISSN 0270-7306

Lee, J. H., Li, Y. C., Doerre, S., Sista, P., Ballard, D. W., Greene, W. C., Franza, B. R. (1991) A member of the set of kappa B binding proteins, HIVEN86A, is a product of the human c-rel proto-oncogene. Oncogene, 6 (4). pp. 665-7.

Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., Parsons, R. (1998) The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Research, 58 (24). pp. 5667-5672. ISSN 0008-5472

Li, J., Yang, Y., Peng, Y., Austin, R. J., van Eyndhoven, G., Nguyen, K. C. Q., Gabriele, T., McCurrach, M. E., Marks, J. R., Hoey, T., Lowe, S. W., Powers, S. (2002) Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23. Nature Genetics, 31 (2). pp. 133-134. ISSN 1061-4036

Li, Y., Lee, J., Mak, G., Ross, J., Franza, B. R. Jr (1991) The Role of the Human Rel Oncogene Product in Control of Transcription by the Human Immunodeficiency Virus Long-Terminal Repeat Hiv1-Ltr Kappab Elements. Journal of Cellular Biochemistry, 47 (Suppl ). p. 58.

Li, Y. C., Niu, G., Franza, B. R. (1994) Transcriptional Activation of Human Cdc2 Gene by an Oncogene, E1a 12s. Journal of Cellular Biochemistry. p. 34. ISSN 0730-2312

Lin, A. W., Lowe, S. W. (2001) Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation. Proceedings of the National Academy of Sciences of the United States of America, 98 (9). pp. 5025-5030. ISSN 0027-8424

Lito, P., Saborowski, A., Yue, J., Solomon, M., Joseph, E., Gadal, S., Saborowski, M., Kastenhuber, E., Fellmann, C., Ohara, K., Morikami, K., Miura, T., Lukacs, C., Ishii, N., Lowe, S., Rosen, N. (2014) Disruption of CRAF-Mediated MEK Activation Is Required for Effective MEK Inhibition in KRAS Mutant Tumors. Cancer Cell, 25 (5). pp. 697-710. ISSN 1878-3686 (Electronic)1535-6108 (Linking)

Lito, P., Saborowski, A., Yue, J. Y., Solomon, M., Joseph, E., Fellman, C., Ohara, K., Morikami, K., Miura, T., Lucas, C., Ishii, N., Lowe, S., Rosen, N. (2014) Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors. Cancer Research, 74 (19). ISSN 0008-5472

Lovén, J., Hoke, H. A, Lin, C. Y., Lau, A. W., Orlando, D. A., Vakoc, C. R., Bradner, J. E., Lee, T. I., Young, R. A. (2013) Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers. Cell, 153 (2). pp. 320-334. ISSN 0092-8674

Lowe, S. (2002) Roles of oncogenes and tumor suppressor genes in apoptosis. European Journal of Cancer, 38. S15-S15. ISSN 0959-8049

Lowe, S. W. (1999) Activation of p53 by oncogenes. Endocr Relat Cancer, 6 (1). pp. 45-8. ISSN 1351-0088 (Print)

Lowe, S. W., Cepero, E., Evan, G. (2004) Intrinsic tumour suppression. Nature, 432 (7015). pp. 307-15. ISSN 1476-4687 (Electronic)

Lowe, S. W., Lin, A. W. (2000) Apoptosis in cancer. Carcinogenesis, 21 (3). pp. 485-495. ISSN 0143-3334

M

Maestro, R., Dei Tos, A. P., Hamamori, Y., Krasnokutsky, S., Sartorelli, V., Kedes, L., Doglioni, C., Beach, D. H., Hannon, G. J. (1999) Twist is a potential oncogene that inhibits apoptosis. Genes and Development, 13 (17). pp. 2207-17. ISSN 0890-9369

Marcus, S., Polverino, A., Chang, E., Robbins, D., Cobb, M. H., Wigler, M. H. (1995) Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast Schizosaccharomyces pombe. Proc Natl Acad Sci U S A, 92 (13). pp. 6180-4. ISSN 0027-8424 (Print)

Martin, K. A., Grant, S. G. N., Hockfield, S. (1992) The mas proto-oncogene is developmentally regulated in the rat central nervous system. Developmental Brain Research, 68 (1). pp. 75-82. ISSN 0165-3806

Mechali, M., Vandewoude, G. F., Hunter, T., Harlow, E., McMahon, A. P., Nurse, P., Verma, I. M. (1990) General Discussion .1. the Role of Protooncogenes in Amphibian Development. Ciba Foundation Symposia, 150. pp. 163-167. ISSN 0300-5208

Moran, E. (1993) DNA tumor virus transforming proteins and the cell cycle. Curr Opin Genet Dev, 3 (1). pp. 63-70. ISSN 0959-437X (Print)

Myers, M. P., Pass, I., Batty, I. H., Van der Kaay, J., Stolarov, J. P., Hemmings, B. A., Wigler, M. H., Downes, C. P., Tonks, N. K. (1998) The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A, 95 (23). pp. 13513-8. ISSN 0027-8424 (Print)

Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., Tonks, N. K. (1997) P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A, 94 (17). pp. 9052-7. ISSN 0027-8424 (Print)

N

Narita, M., Lowe, S. W. (2005) Senescence comes of age. Nature Medicine, 11 (9). pp. 920-922. ISSN 1078-8956

O

Ou, S. H., Bazhenova, L., Camidge, D. R., Solomon, B. J., Herman, J., Kain, T., Bang, Y. J., Kwak, E. L., Shaw, A. T., Salgia, R., Maki, R. G., Clark, J. W., Wilner, K. D., Iafrate, A. J. (2010) Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer. J Thorac Oncol, 5 (12). pp. 2044-6. ISSN 1556-1380 (Electronic)1556-0864 (Linking)

P

Pei, L., Peng, Y., Yang, Y., Ling, X. B., Van Eyndhoven, W. G., Nguyen, K. C., Rubin, M., Hoey, T., Powers, S., Li, J. (2002) PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. Cancer Res, 62 (19). pp. 5420-4. ISSN 0008-5472 (Print)0008-5472

Pei, L., Wiser, O., Slavin, A., Mu, D., Powers, S., Jan, L. Y., Hoey, T. (2003) Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function. Proceedings of the National Academy of Sciences of the United States of America, 100 (13). pp. 7803-7. ISSN 0027-8424

Perna, D., Karreth, F. A., Rust, A. G., Perez-Mancera, P. A., Rashid, M., Iorio, F., Alifrangis, C., Arends, M. J., Bosenberg, M. W., Bollag, G., Tuveson, D. A., Adams, D. J. (2015) BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model. Proceedings of the National Academy of Sciences of the United States of America, 112 (6). E536-E545. ISSN 0027-8424

Perucho, M., Goldfarb, M., Shimizu, K., Lama, C., Fogh, J., Wigler, M. H. (1981) Human-tumor-derived cell lines contain common and different transforming genes. Cell, 27 (3 Pt 2). pp. 467-76. ISSN 0092-8674

Pietenpol, J. A., Stein, R. W., Moran, E., Yaciuk, P., Schlegel, R., Lyons, R. M., Pittelkow, M. R., Munger, K., Howley, P. M., Moses, H. L. (1990) TGF-beta 1 inhibition of c-myc transcription and growth in keratinocytes is abrogated by viral transforming proteins with pRB binding domains. Cell, 61 (5). pp. 777-785. ISSN 0092-8674

Q

Quelle, D. E., Ashmun, R. A., Shurtleff, S. A., Kato, J. Y., Barsagi, D., Roussel, M. F., Sherr, C. J. (1993) Overexpression of Mouse D-Type Cyclins Accelerates G(1) Phase in Rodent Fibroblasts. Genes Dev, 7 (8). pp. 1559-1571. ISSN 0890-9369

R

Rabin, M., Birnbaum, D., Young, D., Birchmeier, C., Wigler, M. H., Ruddle, F. H. (1987) Human ROS1 and MAS1 oncogenes located in regions of chromosome 6 associated with tumor-specific rearrangements. Oncogene Res, 1 (2). pp. 169-78. ISSN 0890-6467 (Print)

Ramsey, M. R., Wilson, C., Ory, B., Rothenberg, S. M., Faquin, W., Mills, A. A., Ellisen, L. W. (2013) FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma. Journal of Clinical Investigation, 123 (8). pp. 3525-3538. ISSN 0021-9738

Rao, L., Debbas, M., Sabbatini, P., Hockenbery, D., Korsmeyer, S., White, E. (1992) The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins. Proceedings of the National Academy of Sciences of the United States of America, 89 (16). pp. 7742-7746. ISSN 0027-8424

Raychaudhuri, P., Bagchi, S., Devoto, S. H., Kraus, V. B., Moran, E., Nevins, J. R. (1991) Domains of the adenovirus E1A protein required for oncogenic activity are also required for dissociation of E2F transcription factor complexes. Genes & Development, 5 (7). pp. 1200-1211. ISSN 0890-9369

Reginato, M. J., Mills, K., Debnath, J., Paulus, J., Muthuswamy, S., Brugge, J. (2002) Bim regulation or lumen formation in epithelial acini is blocked by oncogenes. Molecular Biology of the Cell, 13. 4A-4A. ISSN 1059-1524

Rikitake, Y., Moran, E. (1992) DNA-binding properties of the E1A-associated 300-kilodalton protein. Mol Cell Biol, 12 (6). pp. 2826-36. ISSN 0270-7306 (Print)0270-7306 (Linking)

Roe, J. S., Vakoc, C. R. (2013) Oncogene interference through targeting of chromatin regulators. Cell Cycle, 12 (10). pp. 1475-1476. ISSN 1551-4005 (Electronic)1551-4005 (Linking)

Ryan, J., Barker, P. E., Shimizu, K., Wigler, M. H., Ruddle, F. H. (1983) Chromosomal Assignment of a Family of Human Oncogenes. Proc Natl Acad Sci U S A, 80 (14). pp. 4460-4463. ISSN 0027-8424

S

Saborowski, A., Saborowski, M., Davare, M. A., Druker, B. J., Klimstra, D. S., Lowe, S. W. (2013) Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target. Proceedings of the National Academy of Sciences of the United States of America, 110 (48). pp. 19513-19518. ISSN 00278424 (ISSN)

Scheffzek, K., Grunewald, P., Wohlgemuth, S., Kabsch, W., Tu, H., Wigler, M. H., Wittinghofer, A., Herrmann, C. (2001) The Ras-Byr2RBD complex: Structural basis for Ras effector recognition in yeast. Structure, 9 (11). pp. 1043-1050. ISSN 0969-2126

Schneider, B. L., Bowden, G. T., Sutter, C., Schweizer, J., Han, K. A., Kuleszmartin, M. F. (1993) 7,12-Dimethylbenz[a]Anthracene-Induced Mouse Keratinocyte Malignant Transformation Independent of Harvey Ras Activation. Journal of Investigative Dermatology, 101 (4). pp. 595-599. ISSN 0022-202X

Sdek, P., Ying, H. Q., Zheng, H. W., Margulis, A., Tang, X. R., Tian, K., Xiao, Z. X. J. (2004) The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth. Journal of Biological Chemistry, 279 (51). pp. 53317-53322. ISSN 0021-9258

Seifert, L., Werba, G., Tiwari, S., Giao Ly, N. N., Alothman, S., Alqunaibit, D., Avanzi, A., Barilla, R., Daley, D., Greco, S. H., Torres-Hernandez, A., Pergamo, M., Ochi, A., Zambirinis, C. P., Pansari, M., Rendon, M., Tippens, D., Hundeyin, M., Mani, V. R., Hajdu, C., Engle, D., Miller, G. (2016) The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature, 532 (7598). pp. 245-9. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Sharma, S., Birchmeier, C., Nikawa, J., O'Neill, K., Rodgers, L., Wigler, M. H. (1989) Characterization of the ros1-gene products expressed in human glioblastoma cell lines. Oncogene Res, 5 (2). pp. 91-100. ISSN 0890-6467

Shibuya, E. K., Polverino, A. J., Chang, E., Wigler, M. H., Ruderman, J. V. (1992) Oncogenic Ras triggers the activation of 42-kDa mitogen-activated protein kinase in extracts of quiescent Xenopus oocytes. Proceedings of the National Academy of Sciences of the United States of America, 89 (20). pp. 9831-9835. ISSN 0027-8424

Shimizu, K., Birnbaum, D., Ruley, M. A., Fasano, O., Suard, Y., Edlund, L., Taparowsky, E., Goldfarb, M., Wigler, M. H. (1983) Structure of the Ki-Ras Gene of the Human-Lung Carcinoma Cell-Line Calu-1. Nature, 304 (5926). pp. 497-500. ISSN 0028-0836

Shimizu, K., Goldfarb, M., Perucho, M., Wigler, M. H. (1983) Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line. Proc Natl Acad Sci U S A, 80 (2). pp. 383-387.

Shimizu, K., Goldfarb, M., Suard, Y., Perucho, M., Li, Y., Kamata, T., Feramisco, J., Stavnezer, E., Fogh, J., Wigler, M. H. (1983) Three human transforming genes are related to the viral ras oncogenes. Proceedings of the National Academy of Sciences of the United States of America, 80 (8). pp. 2112-2116. ISSN 0027-8424

Shimizu, K., Taparowsky, E., Fasano, O., Suard, Y., Birnbaum, D., Ruley, M. A., Goldfarb, M., Wigler, M. H. (1983) Structures of 3 Ras Genes Activated in Human-Tumor Cell-Lines. Journal of Cell Biology, 97 (5). A69-A69. ISSN 0021-9525

Singh, Dinesh K., Kollipara, Rahul K., Vemireddy, Vamsidara, Yang, Xiao-Li, Sun, Yuxiao, Regmi, Nanda, Klingler, Stefan, Hatanpaa, Kimmo J., Raisanen, Jack, Cho, Steve K., Sirasanagandla, Shyam, Nannepaga, Suraj, Piccirillo, Sara, Mashimo, Tomoyuki, Wang, Shan, Humphries, Caroline G., Mickey, Bruce, Maher, Elizabeth A., Zheng, Hongwu, Kim, Ryung S., Kittler, Ralf, Bachoo, Robert M. (2017) Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma. Cell Reports, 18 (4). pp. 961-976. ISSN 2211-1247

Spector, D. L., Watt, R. A., Sullivan, N. F. (1987) The v- and c-myc oncogene proteins colocalize in situ with small nuclear ribonucleoprotein particles. Oncogene, 1 (1). pp. 5-12. ISSN 0950-9232

Stein, R. W., Corrigan, M., Yaciuk, P., Whelan, J., Moran, E. (1990) Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity. J Virol, 64 (9). pp. 4421-7. ISSN 0022-538X (Print)0022-538X (Linking)

Sullivan, N. F., Spector, D. L., Watt, R. A. (1987) Association between the Myc-Oncogene Protein and Ribonucleoprotein-Particles. Journal of Cellular Biochemistry, 35 (S11C). p. 42. ISSN 0730-2312

Sullivan, N. F., Watt, R. A., Delannoy, M. R., Green, C. L., Spector, D. L. (1986) Colocalization of the Myc Oncogene Protein and Small Nuclear Ribonucleoprotein Particles. Cold Spring Harbor Symposia on Quantitative Biology, 51. pp. 943-948. ISSN 00917451 (ISSN)

T

Tamanoi, F., Walsh, M., Kataoka, T., Wigler, M. H. (1984) A product of yeast RAS-2 gene is a guanine nucleotide binding protein. Proceedings of the National Academy of Sciences of the United States of America, 81 (22). pp. 6924-6928.

Taparowsky, E., Shimizu, K., Goldfarb, M., Wigler, M. H. (1983) Structure and Activation of the Human N-Ras Gene. Cell, 34 (2). pp. 581-586.

Tasdemir, N., Banito, A., Roe, J. S., Alonso-Curbelo, D., Camiolo, M., Tschaharganeh, D. F., Huang, C. H., Aksoy, O., Bolden, J. E., Chen, C. C., Fennell, M., Thapar, V., Chicas, A., Vakoc, C. R., Lowe, S. W. (2016) BRD4 connects enhancer remodeling to senescence immune surveillance. Cancer Discov, 6 (6). pp. 612-629. ISSN 2159-8290 (Electronic)2159-8274 (Linking)

Taylor, L. K., Marshak, D. R., Landreth, G. E. (1993) Identification of a Nerve Growth Factor-Regulated and Epidermal Growth Factor-Regulated Protein-Kinase That Phosphorylates the Protooncogene Product C-Fos. Proc Natl Acad Sci U S A, 90 (2). pp. 368-372. ISSN 0027-8424

Thorburn, A., Thorburn, J., Chen, S. Y., Powers, S., Shubeita, H. E., Feramisco, J. R., Chien, K. R. (1993) HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. Journal of Biological Chemistry, 268 (3). pp. 2244-9. ISSN 0021-9258

Toda, T., Broek, D., Field, J., Michaeli, T., Cameron, S., Nikawa, J., Sass, P., Birchmeier, C., Powers, S., Wigler, M. H. (1987) Exploring the function of RAS oncogenes by studying the yeast Saccharomyces cerevisiae. In: Oncogenes and cancer : proceedings of the 17th International Symposium of the Princess Takamatsu Cancer Research Fund, Tokyo, 1986. Princess Takamatsu Symposia , 17 . Japan Scientific Societies Press, Tokyo, pp. 253-260. ISBN 4762205176

Toda, T., Uno, I., Ishikawa, T., Powers, S., Kataoka, T., Broek, D., Cameron, S., Broach, J., Matsumoto, K., Wigler, M. H. (1985) In yeast, RAS proteins are controlling elements of adenylate cyclase. Cell, 40 (1). pp. 27-36.

Trotman, L. C., Nowak, D. G., Cho, H., Herzka, T., Watrud, K., DeMarco, D. V., Wang, V. M., Senturk, S., Fellmann, C., Ding, D., Beinortas, T., Kleinman, D., Chen, M., Sordella, R., Wilkinson, J. E., Castillo-Martin, M., Cordon-Cardo, C., Robinson, B. D. (2015) Myc drives Pten/trp53-deficient proliferation and metastasis due to Il6-secretion and Akt-suppression via Phlpp2. Cancer Discovery, 5 (6). pp. 636-651. ISSN 21598274

V

Van Aelst, L. (1998) Two-hybrid analysis of Ras-Raf interactions. Methods in Molecular Biology, 84. pp. 201-22. ISSN 1064-3745 (Print)

Van Aelst, L., Barr, M., Marcus, S., Polverino, A., Wigler, M. H. (1993) Complex formation between RAS and RAF and other protein kinases. Proc Natl Acad Sci U S A, 90 (13). pp. 6213-7. ISSN 0027-8424 (Print)

Van Aelst, L., White, M., Wigler, M. H. (1994) Ras partners. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 181-186. ISSN 00917451 (ISSN)

Vojtek, A., Field, J., Gerst, J., Wigler, M. H. (1991) The Ras Signalling Pathway in Yeast. Journal of Cellular Biochemistry - Supplement.(15 PART B). p. 84.

W

Wagner, E., Noble, M., Heath, J. K., Land, H., Vandewoude, G. F., Harlow, E., Brugge, J. S., Nusse, P., McMahon, A. P. (1990) Cellular Proteins that are Targets for Transformation by DNA Tumour Viruses. In: Proto-Oncogenes in Cell Development. Ciba Foundation Symposium, 150 (150). Wiley, pp. 279-284.

Wang, H. G., Draetta, G., Moran, E. (1991) E1A induces phosphorylation of the retinoblastoma protein independently of direct physical association between the E1A and retinoblastoma products. Mol Cell Biol, 11 (8). pp. 4253-65. ISSN 0270-7306 (Print)0270-7306 (Linking)

Wang, H. G., Yaciuk, P., Ricciardi, R. P., Green, M., Yokoyama, K., Moran, E. (1993) The E1A products of oncogenic adenovirus serotype 12 include amino-terminally modified forms able to bind the retinoblastoma protein but not p300. J Virol, 67 (8). pp. 4804-13. ISSN 0022-538X (Print)

Wang, Y., Boguski, M., Riggs, M., Rodgers, L., Wigler, M. (1991) sar1, a gene from Schizosaccharomyces pombe encoding a protein that regulates ras1. Cell Regulation, 2 (6). pp. 453-465. ISSN 10442030 (ISSN)

Watson, J. D. (1991) Reflections on Oncogenes and Antioncogenes. In: Biology and medicine into the 21st century. Issues in biomedicine, 15 (ED.). S. Karger AG, Basel, pp. 117-126. ISBN 3805553927

Webb, C. P., Van Aelst, L., Wigler, M. H., Woude, G. F. (1998) Signaling pathways in Ras-mediated tumorigenicity and metastasis. Proc Natl Acad Sci U S A, 95 (15). pp. 8773-8. ISSN 0027-8424 (Print)

White, E., Cipriani, R. (1990) Role of adenovirus E1B proteins in transformation: altered organization of intermediate filaments in transformed cells that express the 19-kilodalton protein. Molecular and Cellular Biology, 10 (1). pp. 120-130. ISSN 0270-7306

White, E., Cipriani, R. (1990) Specific Disruption of Intermediate Filaments and the Nuclear Lamina by the 19-Kilodalton Product of the Adenovirus E1b Oncogene. Journal of Cellular Biochemistry, 44 (S14A). p. 233.

White, E., Sabbatini, P., Debbas, M., Wold, W. S., Kusher, D. I., Gooding, L. R. (1992) The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor alpha. Mol Cell Biol, 12 (6). pp. 2570-80. ISSN 0270-7306 (Print)0270-7306 (Linking)

White, M. A., Nicolette, C., Minden, A., Polverino, A., Van Aelst, L., Karin, M., Wigler, M. H. (1995) Multiple Ras functions can contribute to mammalian cell transformation. Cell, 80 (4). pp. 533-41. ISSN 0092-8674 (Print)

White, M. A., Vale, T., Camonis, J. H., Schaefer, E., Wigler, M. H. (1996) A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation. J Biol Chem, 271 (28). pp. 16439-42. ISSN 0021-9258 (Print)

Wigler, M. H. (1990) Oncoproteins. Gaps in Understanding Ras. Nature, 346 (6286). pp. 696-697. ISSN 0028-0836

Wigler, M. H., Ballester, R., Chang, E., Colicelli, J., Field, J., Gerst, J., Kawamukai, M., Michaeli, T., Nicolette, C. (1991) The Ways of Ras. Proceedings American Association for Cancer Research Annual Meeting. p. 435.

Wigler, M. H., Cameron, S., Powers, S., Field, J., Toda, T., Broek, D., Nikawa, J., Michaelis, T., Colicelli, J. (1988) Integration of Ras and Adenylate Cyclase Pathways in Yeast. Journal of Cell Biology, 107 (6 PART). 4A.

Wigler, M. H., Fasano, O., Taparowsky, E., Powers, S., Kataoka, T., Birnbaum, D., Shimizu, K., Goldfarb, M. (1984) Structure and Activation of Ras Genes. In: Oncogenes and viral genes. Cancer cells, 2 (ED.). Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, pp. 419-424. ISBN 0879691697

Wigler, M. H., Field, J., Powers, S., Broek, D., Toda, T., Cameron, S., Nikawa, J., Michaeli, T., Colicelli, J., Ferguson, K. (1988) Studies of RAS function in the yeast Saccharomyces cerevisiae. Cold Spring Harbor Symposia on Quantitative Biology, 53 (2). pp. 649-55. ISSN 00917451 (ISSN)

Wigler, M. H., Goldfarb, M., Shimizu, K., Perucho, M., Suard, Y., Fasano, O., Taparowsky, E., Fogh, J. (1983) Identification Isolation and Characterization of 3 Distinct Human Transforming Genes. In: Genes and proteins in oncogenesis. P & S biomedical sciences symposia series (ED.). Academic Press, New York, pp. 285-292. ISBN 0127424202

Wigler, M. H., Powers, S., Kataoka, T., Toda, T., Fasano, O., Matsumoto, K., Uno, I., Ishikawa, T., Broach, J. (1985) Function of Yeast Ras Genes. In: Genetics, cell differentiation, and cancer. Bristol-Myers cancer symposia, 7 (ED.). Academic Press, Orlando, pp. 153-164.

Wigler, M. H., Xu, H. P., Vanaelst, L., Jung, V., Marcus, S., Polverino, T., Oneill, K., Chang, E., Camonis, J., Nicolette, C., White, M., Ballester, R. (1993) Evolution of Ras Signal Transduction Pathways. Faseb Journal, 7 (7). A1124-A1124. ISSN 0892-6638

Wong, M. W., Henry, R. W., Ma, B., Kobayashi, R., Klages, N., Matthias, P., Strubin, M., Hernandez, N. (1998) The large subunit of basal transcription factor SNAPc is a Myb domain protein that interacts with Oct-1. Molecular and Cellular Biology, 18 (1). pp. 368-77. ISSN 0270-7306 (Print)

X

Xiong, Y., Zhang, H., Beach, D. (1993) Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev, 7 (8). pp. 1572-83. ISSN 0890-9369 (Print)

Xu, H. P., White, M., Marcus, S., Wigler, M. H. (1994) Concerted action of RAS and G proteins in the sexual response pathways of Schizosaccharomyces pombe. Mol Cell Biol, 14 (1). pp. 50-8. ISSN 0270-7306 (Print)

Y

Yaciuk, P., Moran, E. (1991) Analysis with specific polyclonal antiserum indicates that the E1A-associated 300-kDa product is a stable nuclear phosphoprotein that undergoes cell cycle phase-specific modification. Mol Cell Biol, 11 (11). pp. 5389-97. ISSN 0270-7306 (Print)0270-7306 (Linking)

Yang, X. H., Sham, J. S. T., Ng, M. H., Tsao, S. W., Zhang, D. K., Lowe, S. W., Cao, L. (2000) LMP1 of Epstein-Barr virus induces proliferation of primary mouse embryonic fibroblasts and cooperatively transforms the cells with a p16-insensitive CDK4 oncogene. Journal of Virology, 74 (2). pp. 883-891. ISSN 0022-538X

Ying, H. Q., Kimmelman, A. C., Lyssiotis, C. A., Hua, S. J., Chu, G. C., Fletcher-Sananikone, E., Locasale, J. W., Son, J., Zhang, H. L., Coloff, J. L., Yan, H. Y., Wang, W., Chen, S. J., Viale, A., Zheng, H. W., Paik, J. H., Lim, C., Guimaraes, A. R., Martin, E. S., Chang, J., Hezel, A. F., Perry, S. R., Hu, J., Gan, B. Y., Xiao, Y. H., Asara, J. M., Weissleder, R., Wang, Y. A., Chin, L., Cantley, L. C., DePinho, R. A. (2012) Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism. Cell, 149 (3). pp. 656-670. ISSN 0092-8674

Young, D., O'Neill, K., Jessell, T., Wigler, M. H. (1988) Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain. Proc Natl Acad Sci U S A, 85 (14). pp. 5339-42. ISSN 0027-8424

Young, D., Waitches, G., Birchmeier, C., Fasano, O., Wigler, M. H. (1986) Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains. Cell, 45 (5). pp. 711-720.

Z

Zender, L., Spector, M. S., Xue, W., Flemming, P., Cordon-Cardo, C., Silke, J., Fan, S. T., Luk, J. M., Wigler, M. H., Hannon, G. J., Mu, D., Lucito, R., Powers, S., Lowe, S. W. (2006) Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach. Cell, 125 (7). pp. 1253-67. ISSN 0092-8674 (Print)

Zender, L., Spector, M. S., Xue, W., Flemming, P., Mu, D., Cordon-Cardo, C., Powers, S., Hannon, G. J., Lucito, R., Lowe, S. W. (2005) Representational oligonucleotide microarray (ROMA) identifies cIAP1/cIAP2 as candidate oncogenes in mouse and human hepatocarcinogenesis-validation of cIAP1 as a therapeutic target in liver cancer in a new mouse model of hepatocellular carcinoma. Hepatology, 42 (4). 244A-244A. ISSN 0270-9139

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