 | Up a level |
Alpert, S., Hanahan, D., Bautch, V. L. (1989) Targeted Expression of Viral Genes to Pancreatic Beta Cells in Transgenic Mice. In: Concepts in viral pathogenesis III. Springer-Verlag, New York, pp. 177-186. ISBN 9780387969749
Atwal, G. S., Kirchhoff, T., Bond, E. E., Montagna, M., Menin, C., Bertorelle, R., Scaini, M. C., Bartel, F., Böhnke, A., Pempe, C., Gradhand, E., Hauptmann, S., Offit, K., Levine, A. J., Bond, G. L. (June 2009) Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene. Proc Natl Acad Sci U S A, 106 (25). pp. 10236-10241. ISSN 1091-6490 (Electronic)0027-8424 (Linking)
Bagrodia, S., Taylor, S. J., Jordon, K. A., Van Aelst, L., Cerione, R. A. (September 1998) A novel regulator of p21-activated kinases. Journal of Biological Chemistry, 273 (37). pp. 23633-23636. ISSN 0021-9258
Balbín, M., Hannon, G. J., Pendás, A. M., Ferrando, A. A., Vizoso, F., Fueyo, A., López-Otín, C. (1996) Functional analysis of a p21(WAF1,CIP1,SDI1) mutant (Arg 94 → Trp) identified in a human breast carcinoma. Evidence that the mutation impairs the ability of p21 to inhibit cyclin-dependent kinases. Journal of Biological Chemistry, 271 (26). pp. 15782-15786. ISSN 00219258 (ISSN)
Ballard, D. W., Lowenthal, J. W., Bohnlein, E., Franza, B. R., Greene, W. C. (April 1989) Transcriptional Activation of the Interleukin-2 Receptor-Alpha Gene Is Coordinately Regulated by Multiple Inducible and Constitutive DNA-Binding Proteins. Clinical Research, 37 (2). A555-A555. ISSN 0009-9279
Bar-Sagi, Dafna (September 1989) ras proteins: biological effects and biochemical targets (review). Anticancer Res, 9 (5). pp. 1427-37. ISSN 0250-7005
Bardot, E. S., Valdes, V. J., Zhang, J., Perdigoto, C. N., Nicolis, S., Hearn, S. A., Silva, J. M., Ezhkova, E. (May 2013) Polycomb subunits Ezh1 and Ezh2 regulate the Merkel cell differentiation program in skin stem cells. Embo Journal, 32 (14). pp. 1990-2000. ISSN 02614189
Beausejour, C. M., Krtolica, A., Galimi, F., Narita, M., Lowe, S. W., Yaswen, P., Campisi, J. (August 2003) Reversal of human cellular senescence: roles of the p53 and p16 pathways. Embo Journal, 22 (16). pp. 4212-4222. ISSN 0261-4189
Belling, John (1932) "Genes" - the units of heredity. Carnegie Institution of Washington News Service Bulletin, 2 (31). pp. 207-211.
Ben-Hur, V., Denichenko, P., Siegfried, Z., Maimon, A., Krainer, A., Davidson, B., Karni, R. (January 2013) S6K1 Alternative Splicing Modulates Its Oncogenic Activity and Regulates mTORC1. Cell Reports, 3 (1). pp. 103-115. ISSN 22111247
Berger, A. H., Chen, M., Morotti, A., Janas, J. A., Niki, M., Bronson, R. T., Taylor, B. S., Ladanyi, M., Van Aelst, L., Politi, K., Varmus, H. E., Pandolfi, P. P. (2013) DOK2 inhibits EGFR-mutated lung adenocarcinoma. PLoS One, 8 (11). e79526. ISSN 1932-6203
Botcheva, K., McCorkle, S. R., McCombie, W. R., Dunn, J. J., Anderson, C. W. (December 2011) Distinct p53 genomic binding patterns in normal and cancer-derived human cells. Cell Cycle, 10 (24). pp. 4237-4249. ISSN 1538-4101
Bruarolas, J., Chandrasekaran, C., Gordon, J. I., Beach, D., Jacks, T., Hannon, G. J. (1995) Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature, 377 (6549). pp. 552-557. ISSN 00280836 (ISSN)
Buchkovich, K., Dyson, N., Whyte, P., Harlow, E. (1989) Cellular Proteins Implicated in Transformation by Adenovirus and Other DNA Tumor Viruses. In: Common Mechanisms of Transformation by Small DNA Tumor Viruses. American Society for Microbiology, pp. 51-63. ISBN 97815558101391555810136
Bywater, M. J., Poortinga, G., Sanij, E., Hein, N., Peck, A., Cullinane, C., Wall, M., Cluse, L., Drygin, D., Anderes, K., Huser, N., Proffitt, C., Bliesath, J., Haddach, M., Schwaebe, M. K., Ryckman, D. M., Rice, W. G, Schmitt, C., Lowe, Scott W, Johnstone, R. W., Pearson, R. B., McArthur, G. A., Hannan, R. D. (July 2012) Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53. Cancer Cell, 22 (1). pp. 51-65. ISSN 1535-6108
Cai, C. L., Rajaram, M., Zhou, X., Liu, Q., Marchica, J., Li, J. Y., Powers, R. S. (May 2012) Activation of multiple cancer pathways and tumor maintenance function of the 3q amplified oncogene FNDC3B. Cell Cycle, 11 (9). pp. 1773-1781. ISSN 1538-4101
Carnero, A., Hudson, J. D., Hannon, G. J., Beach, D. H. (2000) Loss-of-function genetics in mammalian cells: The p53 tumor suppressor model. Nucleic Acids Research, 28 (11). pp. 2234-2241. ISSN 03051048 (ISSN)
Chakraborty, A. A., Tansey, W. P. (January 2009) Adenoviral E1A Function through Myc. Cancer Res, 69 (1). pp. 6-9.
Charles, C. H., Sun, H., Lau, L. F., Tonks, N. K. (June 1993) The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 90 (11). pp. 5292-5296. ISSN 0027-8424
Chatterjee, S., Seifried, L., Feigin, M. E., Gibbons, D. L., Scuoppo, C., Lin, W., Rizvi, Z. H., Lind, E., Dissanayake, D., Kurie, J., Ohashi, P., Muthuswamy, S. K. (April 2012) Dysregulation of Cell Polarity Proteins Synergize with Oncogenes or the Microenvironment to Induce Invasive Behavior in Epithelial Cells. PLoS ONE, 7 (4). ISSN 1932-6203
Chen, M. H., Herzka, T. M., Zeeman, M. E., Plafker, K. S., Minderer, M., Castillo-Martin, M., Cordon-Cardo, C., Plafker, S. M., Trotman, L. C. (April 2013) PTEN levels are controlled by a nuclear transport receptor in lung cancer. Cancer Research, 73 (8 (Sup). p. 5258. ISSN 0008-5472
Chen, Z., Trotman, L. C., Shaffer, D., Lin, H. K., Dotan, Z. A., Niki, M., Koutcher, J. A., Scher, H. I., Ludwig, T., Gerald, W., Cordon-Cardo, C., Pandolfi, P. P. (August 2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 436 (7051). pp. 725-30. ISSN 1476-4687 (Electronic)0028-0836 (Linking)
Cohen, D. R., Ferreira, P. C. P., Gentz, R., Franza, B. R., Curran, T. (February 1989) The Product of a Fos-Related Gene, Fra-1, Binds Cooperatively to the Ap-1 Site with Jun - Transcription Factor Ap-1 Is Comprised of Multiple Protein Complexes. Genes & Development, 3 (2). pp. 173-184. ISSN 0890-9369
Das, S., Anczuków, O., Akerman, M., Krainer, A. R (2012) Oncogenic Splicing Factor SRSF1 Is a Critical Transcriptional Target of MYC. Cell Reports, 1 (2). pp. 110-117. ISSN 2211-1247
Das, S., Fregoso, O. I., Krainer, A. R. (2013) A new path to oncogene-induced senescence: At the cross-roads of splicing and translation. Cell Cycle, 12 (10). ISSN 1551-4005 (Electronic)1551-4005 (Linking)
Demetrick, D. J., Matsumoto, S., Hannon, G. J., Okamoto, K., Xiong, Y., Zhang, H., Beach, D. H. (1995) Chromosomal mapping of the genes for the human cell cycle proteins cyclin C (CCNC), cyclin E (CCNE), p21 (CDKN1) and KAP (CDKN3). Cytogenetics and Cell Genetics, 69 (3-4). pp. 190-192. ISSN 03010171 (ISSN)
Duelli, D. M., Lazebnik, Y. A. (2000) Primary cells suppress oncogene-dependent apoptosis. Nature Cell Biology, 2 (11). pp. 859-862. ISSN 1465-7392
Eifert, C., Powers, R. S. (June 2012) From cancer genomes to oncogenic drivers, tumour dependencies and therapeutic targets. Nat Rev Cancer, 12 (8). pp. 572-578. ISSN 1474-1768 (Electronic)1474-175X (Linking)
Fearnhead, H. O., McCurrach, M. E., O'Neill, J., Zhang, K., Lowe, S. W., Lazebnik, Y. A. (1997) Oncogene-dependent apoptosis in extracts from drug-resistant cells. Genes Dev, 11 (10). pp. 1266-1276. ISSN 0890-9369
Ferbeyre, G., De Stanchina, E., Lin, A. W., Querido, E., McCurrach, M. E., Hannon, G. J., Lowe, S. W. (2002) Oncogenic ras and p53 cooperate to induce cellular senescence. Molecular and Cellular Biology, 22 (10). pp. 3497-3508. ISSN 02707306 (ISSN)
Fischer, Stephan, Gillis, Jesse (October 2022) Defining the extent of gene function using ROC curvature. Bioinformatics. btac692. ISSN 1367-4803
Freed-Pastor, W. A., Mizuno, H., Zhao, X., Langerød, A., Moon, S. H., Rodriguez-Barrueco, R., Barsotti, A., Chicas, A., Li, W., Polotskaia, A., Bissell, M. J., Osborne, T. F., Tian, B., Lowe, S. W., Silva, J. M., Børresen-Dale, A. L., Levine, A. J., Bargonetti, J., Prives, C. (January 2012) Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell, 148 (1-2). pp. 244-258. ISSN 00928674 (ISSN)
Fregoso, O. I., Das, S., Akerman, M., Krainer, A. R. (March 2013) Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence. Molecular Cell, 50 (1). pp. 56-66. ISSN 1097-2765
Fridman, J. S., Hernando, E., Hemann, M. T., de Stanchina, E., Cordon-Cardo, C., Lowe, S. W. (September 2003) Tumor promotion by Mdm2 splice variants unable to bind p53. Cancer Research, 63 (18). pp. 5703-5706. ISSN 0008-5472
Fridman, J. S., Lowe, S. W. (December 2003) Control of apoptosis by p53. Oncogene, 22 (56). pp. 9030-9040. ISSN 0950-9232
Gunnery, S., Maivali, U., Mathews, M. B. (August 1997) Translation of an uncapped mRNA involves scanning. Journal of Biological Chemistry, 272 (34). pp. 21642-6. ISSN 0021-9258 (Print)
Guo, X., Keyes, W. M., Papazoglu, C., Zuber, J., Li, W., Lowe, S. W., Vogel, H., Mills, A. A. (December 2009) TAp63 induces senescence and suppresses tumorigenesis in vivo. Nat Cell Biol, 11 (12). 1451–1457.
He, X., He, L., Hannon, G. J. (2007) The guardian's little helper: MicroRNAs in the p53 tumor suppressor network. Cancer Research, 67 (23). pp. 11099-11101. ISSN 00085472 (ISSN)
Hein, N., Bywater, M. J., Stanley, K., Verbrugge, I., Cullinane, C., Baker, A., Zuber, H., Rappaport, A., Drygin, D., Huser, N., Bliesath, J., Ryckman, D. M., Rice, W. G., Lowe, S. W., Johnstone, R. W., Pearson, R. B., McArthur, G. A., Hannan, R. D. (November 2011) Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias. Blood, 118 (21). p. 1548. ISSN 0006-4971
Hemish, J., Nakaya, N., Mittal, V., Enikolopov, G. (October 2003) Nitric oxide activates diverse signaling pathways to regulate gene expression. Journal of Biological Chemistry, 278 (43). pp. 42321-42329. ISSN 0021-9258
Hirao, A., Cheung, A., Duncan, G., Girard, P. M., Elia, A. J., Wakeham, A., Okada, H., Sarkissian, T., Wong, J. A., Sakai, T., de Stanchina, E., Bristow, R. G., Suda, T., Lowe, S. W., Jeggo, P. A., Elledge, S. J., Mak, T. W. (September 2002) Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Molecular and Cellular Biology, 22 (18). pp. 6521-6532. ISSN 0270-7306
Hu, W., Feng, Z., Atwal, G. S., Levine, A. J. (April 2008) p53: a new player in reproduction. Cell Cycle, 7 (7). pp. 848-52. ISSN 1551-4005 (Electronic)1551-4005 (Linking)
Hudson, J. D., Shoaibi, M. A., Maestro, R., Carnero, A., Hannon, G. J., Beach, D. H. (1999) A proinflammatory cytokine inhibits p53 tumor suppressor activity. Journal of Experimental Medicine, 190 (10). pp. 1375-1382. ISSN 00221007 (ISSN)
Humbey, O., Pimkina, J., Zilfou, J. T., Jarnik, M., Dominguez-Brauer, C., Burgess, D. J., Eischen, C. M., Murphy, M. E. (December 2008) The ARF Tumor Suppressor Can Promote the Progression of Some Tumors. Cancer Res, 68 (23). pp. 9608-9613.
Issa, G. C., Delmore, J. E., McKeown, M. R., Lemieux, M. E., Rahl, P. B., Jacobs, H. M., Kastritis, E., Gilpatrick, T., Paranal, R. M., Qi, J., Shi, J. W., Chesi, M., Schinzel, A. C., Vakoc, C. R., Bergsagel, P. L., Richardson, P. G., Young, R., Hahn, W. C., Ghobrial, I. M., Anderson, K. C., Kung, A. L., Mitsiades, C. S., Bradner, J. E. (November 2011) Inhibition of c-Myc Expression and Function in Hematologic Malignancies. Blood, 118 (21). p. 1409. ISSN 0006-4971
Janas, J. A., Van Aelst, L. (May 2011) Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Molecular and Cellular Biology, 31 (13). pp. 2552-2565. ISSN 0270-7306
Jones, L., Sevcikova, S., Phan, V., Jain, S., Shieh, A., Dubansky, J., Li, M., Maunakea, M. L., Zhu, G., Tennant, T. R., Lowe, S. W., Le Beau, M. M., Kogan, S. C. (November 2008) Myc Drives Chromosomal Gain in Acute Myeloid Leukemia. Blood, 112 (11). p. 294. ISSN 0006-4971
Kang, H. J., Feng, Z., Sun, Y., Atwal, G., Murphy, M. E., Rebbeck, T. R., Rosenwaks, Z., Levine, A. J., Hu, W. (June 2009) Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans. Proc Natl Acad Sci U S A, 106 (24). pp. 9761-6. ISSN 1091-6490 (Electronic)0027-8424 (Linking)
Kannabiran, C., Morris, G. F., Mathews, M. B. (December 1999) Dual action of the adenovirus E1A 243R oncoprotein on the human proliferating cell nuclear antigen promoter: repression of transcriptional activation by p53. Oncogene, 18 (54). pp. 7825-33. ISSN 0950-9232 (Print)
Karginov, F. V., Hannon, G. J. (July 2013) Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates. Genes and Development, 27 (14). pp. 1624-32. ISSN 08909369 (ISSN)
Karni-Schmidt, O., Castillo-Martin, M., HuaiShen, T., Gladoun, N., Domingo-Domenech, J., Sanchez-Carbayo, M., Li, Y., Lowe, S. W., Prives, C., Cordon-Cardo, C. (2011) Distinct Expression Profiles of p63 Variants during Urothelial Development and Bladder Cancer Progression. The American Journal of Pathology, 178 (3). pp. 1350-1360. ISSN 0002-9440
Keyes, W. M., Mills, A. A. (February 2006) p63: a new link between senescence and aging. Cell Cycle, 5 (3). pp. 260-265. ISSN 15384101
Keyes, W. M. , Pecoraro, M., Aranda, V., Vernersson-Lindahl, E., Li, W., Vogel, H., Guo, X., Garcia, E. L., Michurina, T. V., Enikolopov, G. N., Muthuswamy, S. K., Mills, A. A. (February 2011) DeltaNp63alpha Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis. Cell Stem Cell, 8 (2). pp. 164-76. ISSN 1875-9777 (Electronic)
Kim, S. Y., Cordeiro, M. H., Serna, V. A., Ebbert, K., Butler, L. M., Sinha, S., Mills, A. A., Woodruff, T. K., Kurita, T. (August 2013) Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network. Cell Death and Differentiation, 20 (8). pp. 987-997.
Kim, S. Y., Herbst, A., Tworkowski, K. A., Salghetti, S. E., Tansey, W. P. (May 2003) Skp2 regulates Myc protein stability and activity. Molecular Cell, 11 (5). pp. 1177-1188. ISSN 1097-2765
King, Bryan, Trimarchi, Thomas, Reavie, Linsey, Xu, Luyao, Mullenders, Jasper, Ntziachristos, Panagiotis, Aranda-Orgilles, Beatriz, Perez-Garcia, Arianne, Shi, Junwei, Vakoc, Christopher, Sandy, Peter, Shen, Steven S, Ferrando, Adolfo, Aifantis, Iannis (June 2013) The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability. Cell, 153 (7). pp. 1552-1566. ISSN 0092-8674
Kitzing, T., Xue, W., Roessler, S., Krasnitz, A., Schultz, N., Wang, X. W., Wigler, M., Lowe, S. W. (July 2012) Cooperating Tumor Suppressor Genes on Chromosome 8p Predict Survival Outcome in Hepatocellular Carcinoma. European Journal of Cancer, 48. S139-S139. ISSN 0959-8049
Kondo, S., Lu, Y., Debbas, M., Lin, A. W., Sarosi, I., Itie, A., Wakeham, A., Tuan, J., Saris, C., Elliott, G., Ma, W. L., Benchimol, S., Lowe, S. W., Mak, T. W., Thukral, S. K. (April 2003) Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). Proceedings of the National Academy of Sciences of the United States of America, 100 (9). pp. 5431-5436. ISSN 0027-8424
Krizhanovsky, V., Lowe, S. W. (2009) Stem cells: The promises and perils of p53. Nature, 460 (7259). pp. 1085-1086.
Kurland, J. F., Tansey, W. P. (May 2008) Myc-mediated transcriptional repression by recruitment of histone deacetylase. Cancer Res, 68 (10). pp. 3624-9.
Laska, M. J., Lowe, S. W., Zender, L., Hearn, S. A., Vogel, U., Jensen, U. B., Bric, A., Nexo, B. A. (September 2009) Enforced expression of PPP1R13L increases tumorigenesis and invasion through p53-dependent and p53-independent mechanisms. Mol Carcinog, 48 (9). pp. 832-42.
Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., Parsons, R. (December 1998) The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Research, 58 (24). pp. 5667-5672. ISSN 0008-5472
Li, Z. R., Van Calcar, S., Qu, C. X., Cavenee, W. K., Zhang, M. Q., Ren, B. (July 2003) A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proceedings of the National Academy of Sciences of the United States of America, 100 (14). pp. 8164-8169. ISSN 0027-8424
Li, Rong, Hannon, G. J., Beach, D., Stillman, B. (1996) Subcellular distribution of p21 and PCNA in normal and repair-deficient cells following DNA damage. Current Biology, 6 (2). pp. 189-199. ISSN 09609822 (ISSN)
Lin, A. W., Barradas, M., Stone, J. C., Van Aelst, L., Serrano, M., Lowe, S. W. (October 1998) Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes & Development, 12 (19). pp. 3008-3019. ISSN 0890-9369
Lin, C. J., Nasr, Z., Premsrirut, P. K., Porco Jr, J. A., Hippo, Y., Lowe, S. W., Pelletier, J. (April 2012) Targeting Synthetic Lethal Interactions between Myc and the eIF4F Complex Impedes Tumorigenesis. Cell Reports, 1 (4). pp. 325-333. ISSN 2211-1247
Lo Iacono, N., Mantero, S., Chiarelli, A., Garcia, E. L., Mills, A. A., Morasso, M. I., Costanzo, A., Levi, G., Guerrini, L., Merlo, G. R. (April 2008) Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects. Development, 135 (7). pp. 1377-1388. ISSN 0950-1991
Lovén, J., Hoke, H. A, Lin, C. Y., Lau, A. W., Orlando, D. A., Vakoc, C. R., Bradner, J. E., Lee, T. I., Young, R. A. (April 2013) Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers. Cell, 153 (2). pp. 320-334. ISSN 0092-8674
Lowe, S. (November 2002) Roles of oncogenes and tumor suppressor genes in apoptosis. European Journal of Cancer, 38. S15-S15. ISSN 0959-8049
Lowe, S. W. (March 1999) Activation of p53 by oncogenes. Endocr Relat Cancer, 6 (1). pp. 45-8. ISSN 1351-0088 (Print)
Lujambio, A., Akkari, L., Simon, J., Grace, D., Tschaharganeh, D. F., Bolden, J. E., Zhao, Z., Thapar, V., Joyce, J. A., Krizhanovsky, V., Lowe, S. W. (2013) Non-cell-autonomous tumor suppression by p53. Cell, 153 (2). pp. 449-460.
Ma, O., Cai, W. W., Zender, L., Dayaram, T., Shen, J. H., Herron, A. J., Lowe, S. W., Man, T. K., Lau, C. C., Donehower, L. A. (March 2009) MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), Amplified on Chromosome 9, Collaborate with p53 Deficiency in Mouse Osteosarcoma Progression. Cancer Res, 69 (6). pp. 2559-2567. ISSN 0008-5472
Man, A. K., Young, L. J. T., Tynan, J. A., Lesperance, J., Egeblad, M., Werb, Z., Hauser, C. A., Muller, W. J., Cardiff, R. D., Oshima, R. G. (2003) Ets2-Dependent Stromal Regulation of Mouse Mammary Tumors. Molecular and Cellular Biology, 23 (23). pp. 8614-8625. ISSN 02707306 (ISSN)
Mayo, L. D., Dixon, J. E., Durden, D. L., Tonks, N. K., Donner, D. B. (February 2002) PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. Journal of Biological Chemistry, 277 (7). pp. 5484-5489. ISSN 0021-9258
Miething, C., Scuoppo, C., Lindqvist, L., Reyes, J., Ruse, C., Appelmann, I., Yoon, S., Krasnitz, A., Teruya-Feldstein, J., Pappin, D., Pelletier, J., Lowe, S. (October 2012) An oncogenome-based RNAi screen identifies a tumour suppressor network in B-cell lymphoma relying on the polyamine-hypusine axis. Onkologie, 35. p. 104. ISSN 0378-584X
Mills, A. A., Qi, Y., Bradley, A. (February 2002) Conditional inactivation of p63 by Cre-mediated excision. Genesis, 32 (2). pp. 138-141. ISSN 1526-954X
Mills, A. A., Zheng, B., Wang, X. J., Vogel, H., Roop, D. R., Bradley, A. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature, 398 (6729). pp. 708-713. ISSN 00280836 (ISSN)
Molz, L., Booher, R., Young, P., Beach, D. (August 1989) cdc2 and the regulation of mitosis: six interacting mcs genes. Genetics, 122 (4). pp. 773-82. ISSN 0016-6731
Moretti, F., Marinari, B., Iacono, N. L., Botti, E., Giunta, A., Spallone, G., Garaffo, G., Vernersson-Lindahl, E., Merlo, G., Mills, A. A., Ballaro, C., Alema, S., Chimenti, S., Guerrini, L., Costanzo, A. (May 2010) A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. Journal of Clinical Investigation, 120 (5). pp. 1570-1577.
Moretti, F., Spallone, G., Botti, E., Giunta, A., Lo Iacono, N., Merlo, G., Mills, A. A., Alema, S., Chimenti, S., Guerrini, L., Costanzo, A. (April 2010) p63 and IRF6 are components of a common molecular pathway disrupted in ectodermal dysplasias. Journal of Investigative Dermatology, 130. p. 626. ISSN 0022-202X
Murn, J., Mlinaric-Rascan, I., Vaigot, P., Alibert, O., Frouin, V., Gidrol, X. (July 2009) A Myc-regulated transcriptional network controls B-cell fate in response to BCR triggering. BMC Genomics, 10. p. 323.
Muthuswamy, S. K., Li, D. M., Lelievre, S., Bissell, M. J., Brugge, J. S. (September 2001) ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nature Cell Biology, 3 (9). pp. 785-792. ISSN 1465-7392
Naguib, A., Bencze, G., Faehnle, C. R., Schalch, T., Lazar, Z., Ruse, C. I., Joshua-Tor, L., Pappin, D. J., Trotman, L. C. (April 2013) Upstream activation of PTEN. Cancer Research, 73 (8 (Sup). p. 5156. ISSN 0008-5472
Okamoto, A., Hussain, S. P., Hagiwara, K., Spillare, E. A., Rusin, M. R., Demetrick, D. J., Serrano, M., Hannon, G. J., Shiseki, M., Zariwala, M., Xiong, Y., Beach, D. H., Yokota, J., Harris, C. C. (1995) Mutations in the p16(INK4)/MTS1/CDKN2, p15(INK4B)/MTS2, and p18 genes in primary and metastatic lung cancer. Cancer Research, 55 (7). pp. 1448-1451. ISSN 00085472 (ISSN)
Olson, A. J., Tully, T., Sachidanandam, R. (2005) GeneSeer: a sage for gene names and genomic resources. BMC Genomics, 6 (1). p. 134. ISSN 1471-2164 (Electronic)
Pardee, T., Zuber, J., Lowe, S. W. (November 2009) The Flt3 ITD Accelerates An Already Established Myeloid Leukemia and Alters Chemotherapy Response In Vitro and In Vivo in a p53 Dependent Manner. Blood, 114 (22). p. 685. ISSN 0006-4971
Park, E., Kim, H., Kim, J. M., Primack, B., Vidal-Cardenas, S., Xu, Y., Price, B. D., Mills, A. A., D’Andrea, A. D. (June 2013) FANCD2 Activates Transcription of TAp63 and Suppresses Tumorigenesis. Molecular Cell, 50 (6). pp. 908-918. ISSN 1097-2765
Piccini, A., Malinow, R. (July 2002) Critical postsynaptic density 95/disc large/zonula occludens-1 interactions by glutamate receptor 1 (GluR1) and GluR2 required at different subcellular sites. Journal of Neuroscience, 22 (13). pp. 5387-5392. ISSN 0270-6474
Reginato, M. J., Mills, K., Debnath, J., Paulus, J., Muthuswamy, S., Brugge, J. (November 2002) Bim regulation or lumen formation in epithelial acini is blocked by oncogenes. Molecular Biology of the Cell, 13. 4A-4A. ISSN 1059-1524
Roe, J. S., Vakoc, C. R. (2013) Oncogene interference through targeting of chromatin regulators. Cell Cycle, 12 (10). pp. 1475-1476. ISSN 1551-4005 (Electronic)1551-4005 (Linking)
Saborowski, A., Saborowski, M., Davare, M. A., Druker, B. J., Klimstra, D. S., Lowe, S. W. (November 2013) Mouse model of intrahepatic cholangiocarcinoma validates FIG-ROS as a potent fusion oncogene and therapeutic target. Proceedings of the National Academy of Sciences of the United States of America, 110 (48). pp. 19513-19518. ISSN 00278424 (ISSN)
Schmitt, C. A., Fridman, J. S., Yang, M., Baranov, E., Hoffman, R. M., Lowe, S. W. (April 2002) Dissecting p53 tumor suppressor functions in vivo. Cancer Cell, 1 (3). pp. 289-298. ISSN 1535-6108
Schmitt, C. A., Fridman, J. S., Yang, M., Lee, S., Baranov, E., Hoffman, R. M., Lowe, S. W. (May 2002) A senescence program controlled by p53 and p16(INK4a) contributes to the outcome of cancer therapy. Cell, 109 (3). pp. 335-346. ISSN 0092-8674
Schmitt, C. A., McCurrach, M. E., de Stanchina, E., Wallace-Brodeur, R. R., Lowe, S. W. (October 1999) INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes and Development, 13 (20). pp. 2670-7. ISSN 0890-9369 (Print)
Scott, C. L., Gil, J., Hernando, E., Teruya-Feldstein, J., Narita, M., Martinez, D., Visakorpi, T., Mu, D., Cordon-Cardo, C., Peters, G., Beach, D., Lowe, S. W. (March 2007) Role of the chromobox protein CBX7 in lymphomagenesis. Proc Natl Acad Sci U S A, 104 (13). pp. 5389-94. ISSN 0027-8424 (Print)
Shi, J., Whyte, W. A., Zepeda-Mendoza, C. J., Milazzo, J. P., Shen, C., Roe, J. S., Minder, J. L., Mercan, F., Wang, E., Eckersley-Maslin, M. A., Campbell, A. E., Kawaoka, S., Shareef, S., Zhu, Z., Kendall, J., Muhar, M., Haslinger, C., Yu, M., Roeder, R. G., Wigler, M. A., Blobel, G. A., Zuber, J., Spector, D. L., Young, R. A., Vakoc, C. R. (November 2013) Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes and Development, 27 (24). pp. 264-273. ISSN 08909369 (ISSN)
Simpson, D. R., Yu, M., Zheng, S. Y., Zhao, Z. M., Muthuswamy, S. K., Tansey, W. P. (June 2011) Epithelial Cell Organization Suppresses Myc Function by Attenuating Myc Expression. Cancer Research, 71 (11). pp. 3822-3830. ISSN 0008-5472
Storm, P., Aits, S., Puthia, M. K., Urbano, A., Northen, T., Powers, S., Bowen, B., Chao, Y., Reindl, W., Lee, D. Y., Sullivan, N. L., Zhang, J., Trulsson, M., Yang, H., Watson, J. D., Svanborg, C. (June 2011) Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis. Oncogene, 30 (48). pp. 4765-4779. ISSN 09509232 (ISSN)
Streppel, M. M., Lata, S., Delabastide, M., Montgomery, E. A., Wang, J. S., Canto, M. I., Macgregor-Das, A. M., Pai, S., Morsink, F. H., Offerhaus, G. J., Antoniou, E., Maitra, A., McCombie, W. R. (January 2014) Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett's esophagus. Oncogene, 33 (3). pp. 347-57. ISSN 0950-9232
Sun, H., Tonks, N. K. (November 1994) The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends in Biochemical Sciences, 19 (11). pp. 480-485. ISSN 0968-0004
Tai, Y., Janas, J. A., Wang, C. L., Van Aelst, L. (January 2014) Regulation of Chandelier Cell Cartridge and Bouton Development via DOCK7-Mediated ErbB4 Activation. Cell Reports, 6 (2). pp. 254-63. ISSN 22111247 (ISSN)
Thorburn, A., Thorburn, J., Chen, S. Y., Powers, S., Shubeita, H. E., Feramisco, J. R., Chien, K. R. (January 1993) HRas-dependent pathways can activate morphological and genetic markers of cardiac muscle cell hypertrophy. Journal of Biological Chemistry, 268 (3). pp. 2244-9. ISSN 0021-9258
Timmermans, M. C. P., Hudson, A., Becraft, P. W., Nelson, T. (April 1999) ROUGH SHEATH2: A Myb protein that represses knox homeobox genes in maize lateral organ primordia. Science, 284 (5411). pp. 151-153. ISSN 0036-8075
Tonks, N. K., Myers, M. P. (December 1999) Structural assets of a tumor suppressor. Science, 286 (5447). pp. 2096-2097. ISSN 0036-8075
Tully, T. (November 1996) Discovery of genes involved with learning and memory: an experimental synthesis of Hirschian and Benzerian perspectives. Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 13460-7. ISSN 0027-8424
Tworkowski, K. A., Chakraborty, A. A., Samuelson, A. V., Seger, Y. R., Narita, M., Hannon, G. J., Lowe, S. W., Tansey, W. P. (April 2008) Adenovirus E1A targets p400 to induce the cellular oncoprotein Myc. Proc Natl Acad Sci U S A, 105 (16). pp. 6103-6108.
Van Stry, M., Oguin Iii, T. H., Cheloufi, S., Vogel, P., Watanabe, M., Pillai, M. R., Dash, P., Thomas, P. G., Hannon, G. J., Bix, M. (2012) Enhanced susceptibility of Ago1/3 double-null mice to influenza a virus infection. Journal of Virology, 86 (8). pp. 4151-4157. ISSN 0022538X (ISSN)
Vernersson Lindahl, E., Garcia, E. L., Mills, A. A. (June 2013) An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. American Journal of Medical Genetics Part A, 161 (8). pp. 1961-1971. ISSN 1552-4825
Vestin, A., Mills, A. A. (October 2013) The tumor suppressor Chd5 is induced during neuronal differentiation, in the developing mouse brain. Gene Expression Patterns, 13 (8). pp. 482-489. ISSN 1872-7298 (Electronic)1567-133X (Linking)
Vignais, M. L., Gilman, M. (May 1999) Distinct mechanisms of activation of Stat1 and Stat3 by platelet-derived growth factor receptor in a cell-free system. Molecular and Cellular Biology, 19 (5). pp. 3727-35. ISSN 0270-7306 (Print)
Wall, M., Poortinga, G., Stanley, K. L., Lindemann, R. K., Bots, M., Chan, C. J., Bywater, M. J., Kinross, K. M., Astle, M. V., Waldeck, K., Hannan, K. M., Shortt, J., Smyth, M. J., Lowe, S. W., Hannan, R. D., Pearson, R. B., Johnstone, R. W., McArthur, G. A. (January 2013) The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence. Cancer Discovery, 3 (1). pp. 82-95. ISSN 21598274
Wang, J., Xie, L. Y., Allan, S., Beach, D., Hannon, G. J. (1998) Myc activates telomerase. Genes and Development, 12 (12). pp. 1769-1774. ISSN 08909369 (ISSN)
Xiang, B., Chatti, K., Qiu, H., Lakshmi, B., Krasnitz, A., Hicks, J. B., Yu, M., Miller, W. T., Muthuswamy, S. K. (August 2008) Brk is coamplified with ErbB2 to promote proliferation in breast cancer. Proc Natl Acad Sci U S A, 105 (34). pp. 12463-8.
Zhang, H., Hannon, G. J., Casso, D., Beach, D. (1994) p21 is a component of active cell cycle kinases. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 21-29. ISSN 00917451 (ISSN)
Zhang, Y., Shin, S. J., Liu, D., Ivanova, E., Foerster, F., Ying, H., Zheng, H., Xiao, Y., Chen, Z., Protopopov, A., Depinho, R. A., Paik, J. H. (June 2013) ZNF365 Promotes Stability of Fragile Sites and Telomeres. Cancer Discovery, 3 (7). pp. 798-811. ISSN 21598274
