Items where Subject is "KRAS"

A

Arbour, KC, Manchado, E, Bott, MJ, Ahn, L, Tobi, Y, Ni, AA, Yu, HA, Shannon, A, Ladanyi, M, Perron, V, Ginsberg, MS, Johnson, A, Holodny, A, Kris, MG, Rudin, CM, Lito, P, Rosen, N, Lowe, S, Riely, GJ (January 2022) Phase 1 Clinical Trial of Trametinib and Ponatinib in Patients With NSCLC Harboring KRAS Mutations. JTO Clinical and Research Reports, 3 (1). p. 100256. ISSN 2666-3643 (In Press)

C

Cheng, D., Tuveson, D. (January 2018) Kras in Organoids. Cold Spring Harb Perspect Med, 8 (10). ISSN 2157-1422

H

Humpton, T. J., Alagesan, B., DeNicola, G. M., Lu, D., Yordanov, G. N., Leonhardt, C. S., Yao, M. A., Alagesan, P., Zaatari, M. N., Park, Y., Skepper, J. N., Macleod, K. F., Perez-Mancera, P. A., Murphy, M. P., Evan, G. I., Vousden, K. H., Tuveson, D. A. (July 2019) Oncogenic Kras induces Nix-mediated mitophagy to promote pancreatic cancer. Cancer Discov, 99 (9). pp. 1268-1298. ISSN 2159-8274

L

Li, J., Sordella, R., Powers, S. (June 2016) Effectors and potential targets selectively upregulated in human KRAS-mutant lung adenocarcinomas. Sci Rep, 6. p. 27891. ISSN 2045-2322 (Electronic)2045-2322 (Linking)

Ludwig, M. R., Kojima, K., Bowersock, G. J., Chen, D., Jhala, N. C., Buchsbaum, D. J., Grizzle, W. E., Klug, C. A., Mobley, J. A. (February 2016) Surveying the serologic proteome in a tissue specific kras(G12D) knockin mouse model of pancreatic cancer. Proteomics, 16 (3). pp. 516-31. ISSN 1615-9861 (Electronic)1615-9853 (Linking)

M

Manchado, E., Weissmueller, S., Morris, J. P., Chen, C. C., Wullenkord, R., Lujambio, A., de Stanchina, E., Poirier, J. T., Gainor, J. F., Corcoran, R. B., Engelman, J. A., Rudin, C. M., Rosen, N., Lowe, S. W. (June 2016) A combinatorial strategy for treating KRAS-mutant lung cancer. Nature, 534. pp. 647-51. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

McFadden, D. G., Politi, K., Bhutkar, A., Chen, F. K., Song, X., Pirun, M., Santiago, P. M., Kim-Kiselak, C., Platt, J. T., Lee, E., Hodges, E., Rosebrock, A. P., Bronson, R. T., Socci, N. D., Hannon, G. J., Jacks, T., Varmus, H. (October 2016) Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma. Proc Natl Acad Sci U S A, 113 (42). E6409-E6417. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

R

Ruscetti, M., Leibold, J., Bott, M. J., Shields, M., Chen, C. C., Fennell, M., Chen, H. C., Baslan, T., Salgado, N. R., Manchado, E., Low, V., Poirier, J. T., Rudin, C. M., de Stanchina, E., Egeblad, M., Sherr, C. J., Lowe, S. W. (May 2018) Targeted therapy-induced senescence enhances immune surveillance of KRAS mutant lung cancers. Cancer Research, 78 (10 Sup). ISSN 0008-5472

W

Wan, Ledong, Lin, Kuan-Ting, Rahman, Mohammad Alinoor, Wang, Zhikai, Jensen, Mads, Park, Youngkyu, Tuveson, David, Krainer, Adrian (2021) Loss of KRAS G12D feedback regulation involving splicing factor SRSF1 accelerates pancreatic cancer. bioRxiv. (Submitted)

Y

Yuan, T. L., Amzallag, A., Bagni, R., Yi, M., Afghani, S., Burgan, W., Fer, N., Strathern, L. A., Powell, K., Smith, B., Waters, A. M., Drubin, D., Thomson, T., Liao, R., Greninger, P., Stein, G. T., Murchie, E., Cortez, E., Egan, R. K., Procter, L., Bess, M., Cheng, K. T., Lee, C. S., Lee, L. C., Fellmann, C., Stephens, R., Luo, J., Lowe, S. W., Benes, C. H., McCormick, F. (February 2018) Differential Effector Engagement by Oncogenic KRAS. Cell Rep, 22 (7). pp. 1889-1902.

Yun, J., Mullarky, E., Lu, C., Bosch, K. N., Kavalier, A., Rivera, K., Roper, J., Chio, II, Giannopoulou, E. G., Rago, C., Muley, A., Asara, J. M., Paik, J., Elemento, O., Chen, Z., Pappin, D. J., Dow, L. E., Papadopoulos, N., Gross, S. S., Cantley, L. C. (December 2015) Vitamin C selectively kills KRAS and BRAF mutant colorectal cancer cells by targeting GAPDH. Science, 350 (6266). pp. 1391-1396. ISSN 1095-9203 (Electronic)0036-8075 (Linking)