Items where Subject is "bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > p53"

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Number of items at this level: 102.

A

Alimonti, A., Nardella, C., Chen, Z., Clohessy, J. G., Carracedo, A., Trotman, L. C., Cheng, K., Varmeh, S., Kozma, S. C., Thomas, G., Rosivatz, E., Woscholski, R., Cognetti, F., Scher, H. I., Pandolfi, P. P. (2010) A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis. Journal of Clinical Investigation, 120 (3). pp. 681-693. ISSN 00219738 (ISSN)

Attardi, L. D., Reczek, E. E., Cosmas, C., Demicco, E. G., McCurrach, M. E., Lowe, S. W., Jacks, T. (2000) PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. Genes & Development, 14 (6). pp. 704-718. ISSN 0890-9369

Atwal, G. S., Bond, G. L., Metsuyanim, S., Papa, M., Friedman, E., Distelman-Menachem, T., Ben Asher, E., Lancet, D., Ross, D. A., Sninsky, J., White, T. J., Levine, A. J., Yarden, R. (2007) Haplotype structure and selection of the MDM2 oncogene in humans. Proc Natl Acad Sci U S A, 104 (11). pp. 4524-9. ISSN 0027-8424 (Print) 0027-8424 (Linking)

B

Bar-Sagi, D., Lees, J., Sherr, C., Weiss, W. (2010) MECHANISMS & MODELS OF CANCER. In: 2010 meeting of MECHANISMS & MODELS OF CANCER, August 17–August 21, 2010, Cold Spring Harbor Laboratory.

Bargonetti, J., Manfredi, J. J., Chen, X. B., Marshak, D. R., Prives, C. (1993) A Proteolytic Fragment from the Central Region of P53 Has Marked Sequence-Specific DNA-Binding Activity When Generated from Wild-Type but Not from Oncogenic Mutant P53-Protein. Genes Dev, 7 (12B). pp. 2565-2574. ISSN 0890-9369

Beausejour, C. M., Krtolica, A., Galimi, F., Narita, M., Lowe, S. W., Yaswen, P., Campisi, J. (2003) Reversal of human cellular senescence: roles of the p53 and p16 pathways. Embo Journal, 22 (16). pp. 4212-4222. ISSN 0261-4189

Bischoff, J. R., Casso, D., Beach, D. (1991) Expression of Human P53 in Fission Yeast. Journal of Cellular Biochemistry, 47 (Suppl ). p. 65.

Bischoff, J. R., Casso, D., Beach, D. (1992) Human p53 inhibits growth in Schizosaccharomyces pombe. Mol Cell Biol, 12 (4). pp. 1405-11. ISSN 0270-7306 (Print)0270-7306 (Linking)

Bischoff, J. R., Casso, D., Beach, D. (1991) A Yeast System to Study Human P53. In: Origins of human cancer: a comprehensive review. Cold Spring Harbor Laboratory Press, Plainview, N. Y., pp. 51-63. ISBN 0879694041

Bischoff, J. R., Friedman, P. N., Marshak, D. R., Prives, C., Beach, D. (1990) Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. Proc Natl Acad Sci U S A, 87 (12). pp. 4766-70. ISSN 0027-8424 (Print)0027-8424 (Linking)

Botcheva, K., McCorkle, S. R., McCombie, W. R., Dunn, J. J., Anderson, C. W. (2011) Distinct p53 genomic binding patterns in normal and cancer-derived human cells. Cell Cycle, 10 (24). pp. 4237-4249. ISSN 1538-4101

Bywater, M. J., Poortinga, G., Sanij, E., Hein, N., Peck, A., Cullinane, C., Wall, M., Cluse, L., Drygin, D., Anderes, K., Huser, N., Proffitt, C., Bliesath, J., Haddach, M., Schwaebe, M. K., Ryckman, D. M., Rice, W. G, Schmitt, C., Lowe, Scott W, Johnstone, R. W., Pearson, R. B., McArthur, G. A., Hannan, R. D. (2012) Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53. Cancer Cell, 22 (1). pp. 51-65. ISSN 1535-6108

C

Carnero, A., Hudson, J. D., Hannon, G. J., Beach, D. H. (2000) Loss-of-function genetics in mammalian cells: The p53 tumor suppressor model. Nucleic Acids Research, 28 (11). pp. 2234-2241. ISSN 03051048 (ISSN)

Casso, D., Beach, D. (1996) A mutation in a thioredoxin reductase homolog suppresses p53-induced growth inhibition in the fission yeast Schizosaccharomyces pombe. Mol Gen Genet, 252 (5). pp. 518-29. ISSN 0026-8925 (Print)

Chen, Z., Trotman, L. C., Shaffer, D., Lin, H. K., Dotan, Z. A., Niki, M., Koutcher, J. A., Scher, H. I., Ludwig, T., Gerald, W., Cordon-Cardo, C., Pandolfi, P. P. (2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 436 (7051). pp. 725-30. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Chen, Z., Trotman, L. C., Shaffer, D., Lin, H. K., Dotan, Z. A., Niki, M., Koutcher, J. A., Scher, H. I., Ludwig, T., Gerald, W., Cordon-Cardo, C., Pandolfi, P. P. (2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 436 (7051). pp. 725-30. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Chien, Y., Scuoppo, C., Wang, X., Fang, X., Balgley, B., Bolden, J. E., Premsrirut, P., Luo, W., Chicas, A., Lee, C. S., Kogan, S. C., Lowe, S. W. (2011) Control of the senescence-associated secretory phenotype by NF-kappaB promotes senescence and enhances chemosensitivity. Genes Dev, 25 (20). pp. 2125-36. ISSN 1549-5477 (Electronic) 0890-9369 (Linking)

D

Dickins, R. A., McJunkin, K., Hernando, E., Premsrirut, P. K., Krizhanovsky, V., Burgess, D. J., Kim, S. Y., Cordon-Cardo, C., Zender, L., Hannon, G. J., Lowe, S. W. (2007) Tissue-specific and reversible RNA interference in transgenic mice. Nat Genet, 39 (7). 914 - 921. ISSN 1061-4036 (Print)

Dickins, R. A., Premsrirut, P., McJunkin, K., Kim, S. Y., Hannon, G. J., Lowe, S. W. (2006) Tetracycline-regulated p53 knockdown in cells and transgenic mice. Toxicologic Pathology, 34 (7). p. 1006. ISSN 0192-6233

Duelli, D. M., Padilla-Nash, H. M., Berman, D., Murphy, K. M., Ried, T., Lazebnik, Y. (2007) A virus causes cancer by inducing massive chromosomal instability through cell fusion. Current Biology, 17 (5). pp. 431-7. ISSN 0960-9822 (Print)

de Stanchina, E., McCurrach, M. E., Zindy, F., Shieh, S. Y., Ferbeyre, G., Samuelson, A. V., Prives, C., Roussel, M. F., Sherr, C. J., Lowe, S. W. (1998) E1A signaling to p53 involves the p19(ARF) tumor suppressor. Genes Dev, 12 (15). pp. 2434-42. ISSN 0890-9369 (Print)

de Stanchina, E., Querido, E., Narita, M., Davuluri, R. V., Pandolfi, P. P., Ferbeyre, G., Lowe, S. W. (2004) PML is a direct p53 target that modulates p53 effector functions. Mol Cell, 13 (4). pp. 523-35. ISSN 1097-2765 (Print)

F

Feng, Z., Jin, S., Zupnick, A., Hoh, J., De Stanchina, E., Lowe, S. W., Prives, C., Levine, A. J. (2006) p53 tumor suppressor protein regulates the levels of huntingtin gene expression. Oncogene, 25 (1). pp. 1-7. ISSN 09509232

Feng, Z. H., Hu, W. W., De Stanchina, E., Teresky, A. K., Jin, S. K., Lowe, S. W., Levine, A. J. (2007) The regulation of AMPK beta 1, TSC2, and PTEN expression by p53: Stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Research, 67 (7). pp. 3043-3053. ISSN 0008-5472

Ferbeyre, G., De Stanchina, E., Lin, A. W., Querido, E., McCurrach, M. E., Hannon, G. J., Lowe, S. W. (2002) Oncogenic ras and p53 cooperate to induce cellular senescence. Molecular and Cellular Biology, 22 (10). pp. 3497-3508. ISSN 02707306 (ISSN)

Freed-Pastor, W. A., Mizuno, H., Zhao, X., Langerød, A., Moon, S. H., Rodriguez-Barrueco, R., Barsotti, A., Chicas, A., Li, W., Polotskaia, A., Bissell, M. J., Osborne, T. F., Tian, B., Lowe, S. W., Silva, J. M., Børresen-Dale, A. L., Levine, A. J., Bargonetti, J., Prives, C. (2012) Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway. Cell, 148 (1-2). pp. 244-258. ISSN 00928674 (ISSN)

Fregoso, O. I., Das, S., Akerman, M., Krainer, A. R. (2013) Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence. Molecular Cell, 50 (1). pp. 56-66. ISSN 1097-2765

Fridman, J. S., Hernando, E., Hemann, M. T., de Stanchina, E., Cordon-Cardo, C., Lowe, S. W. (2003) Tumor promotion by Mdm2 splice variants unable to bind p53. Cancer Research, 63 (18). pp. 5703-5706. ISSN 0008-5472

Fridman, J. S., Lowe, S. W. (2003) Control of apoptosis by p53. Oncogene, 22 (56). pp. 9030-9040. ISSN 0950-9232

G

Grochola, Lukasz F., Zeron-Medina, Jorge, Repapi, Emmanouela, Finlayson, Alexander E., Cai, Ying, Atwal, Gurinder Singh, Bond, Gareth L. (2013) The Inheritance of p53. In: p53 in the Clinics. Springer New York, pp. 25-46. ISBN 978-1-4614-3675-1

Guo, X. C., Mills, A. A. (2007) p63, cellular senescence and tumor development. Cell Cycle, 6 (3). pp. 305-11. ISSN 1538-4101

H

Ha, L., Ichikawa, T., Anver, M., Dickins, R. A., Lowe, S. W., Sharpless, N E., Krimpenfort, P , DePinho, R. A., Bennett, D. C., Sviderskaya, E. V., Merlino, G. (2007) ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence. Proc Natl Acad Sci U S A, 104 (26). 10968-10973 . ISSN 0027-8424 (Print)

Hannon, G. J., Sun, P., Carnero, A., Xie, L. Y., Maestro, R., Conklin, D. S., Beach, D. (1999) MaRX: an approach to genetics in mammalian cells. Science, 283 (5405). pp. 1129-30. ISSN 0036-8075

He, L., He, X., Lim, L. P., De Stanchina, E., Xuan, Z., Liang, Y., Xue, W., Zender, L., Magnus, J., Ridzon, D., Jackson, A. L., Linsley, P. S., Chen, C., Lowe, S. W., Cleary, M. A., Hannon, G. J. (2007) A microRNA component of the p53 tumour suppressor network. Nature, 447 (7148). pp. 1130-4. ISSN 1476-4687 (Electronic)

He, L., He, X., Lowe, S. W., Hannon, G. J. (2007) microRNAs join the p53 network - another piece in the tumour-suppression puzzle. Nat Rev Cancer, 7 (11). pp. 819-822. ISSN 1474-1768 (Electronic)

He, X., He, L., Hannon, G. J. (2007) The guardian's little helper: MicroRNAs in the p53 tumor suppressor network. Cancer Research, 67 (23). pp. 11099-11101. ISSN 00085472 (ISSN)

Hein, N., Bywater, M. J., Stanley, K., Verbrugge, I., Cullinane, C., Baker, A., Zuber, H., Rappaport, A., Drygin, D., Huser, N., Bliesath, J., Ryckman, D. M., Rice, W. G., Lowe, S. W., Johnstone, R. W., Pearson, R. B., McArthur, G. A., Hannan, R. D. (2011) Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias. Blood, 118 (21). p. 673. ISSN 0006-4971

Hemann, M. T., Bric, A., Teruya-Feldstein, J., Herbst, A., Nilsson, J. A., Cordon-Cardo, C., Cleveland, J. L., Tansey, W. P., Lowe, S. W. (2005) Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature, 436 (7052). pp. 807-11. ISSN 1476-4687 (Electronic)

Hemann, M. T., Fridman, J. S., Zilfou, J. T., Hernando, E., Paddison, P. J., Cordon-Cardo, C., Hannon, G. J., Lowe, S. W. (2003) An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo. Nature Genetics, 33 (3). pp. 396-400. ISSN 1061-4036

Hemann, M. T., Lowe, S. W. (2006) The p53-Bcl-2 connection. Cell Death Differ, 13 (8). pp. 1256-9. ISSN 1350-9047 (Print)

Hemann, M. T., Zilfou, J. T., Zhao, Z., Burgess, D. J., Hannon, G. J., Lowe, S. W. (2004) Suppression of tumorigenesis by the p53 target PUMA. Proc Natl Acad Sci U S A, 101 (25). pp. 9333-8. ISSN 0027-8424 (Print)

Hemish, J., Nakaya, N., Mittal, V., Enikolopov, G. (2003) Nitric oxide activates diverse signaling pathways to regulate gene expression. Journal of Biological Chemistry, 278 (43). pp. 42321-42329. ISSN 0021-9258

Holembowski, L., Kramer, D., Riedel, D., Sordella, R., Nemajerova, A., Dobbelstein, M., Moll, U. M. (2014) Tap73 is essential for germ cell adhesion and maturation in testis. Journal of Cell Biology, 204 (7). pp. 1173-1190. ISSN 15408140

Hu, W., Feng, Z., Atwal, G. S., Levine, A. J. (2008) p53: a new player in reproduction. Cell Cycle, 7 (7). pp. 848-52. ISSN 1551-4005 (Electronic)1551-4005 (Linking)

Hudson, J. D., Shoaibi, M. A., Maestro, R., Carnero, A., Hannon, G. J., Beach, D. H. (1999) A proinflammatory cytokine inhibits p53 tumor suppressor activity. Journal of Experimental Medicine, 190 (10). pp. 1375-1382. ISSN 00221007 (ISSN)

I

Italiano, A., Chen, C. L., Thomas, R., Breen, M., Bonnet, F., Sevenet, N., Longy, M., Maki, R. G., Coindre, J. M., Antonescu, C. R. (2012) Alterations of the p53 and PIK3CA/AKT/mTOR pathways in angiosarcomas: a pattern distinct from other sarcomas with complex genomics. Cancer, 118 (23). pp. 5878-87. ISSN 1097-0142 (Electronic)0008-543X (Linking)

K

Kang, H. J., Feng, Z., Sun, Y., Atwal, G., Murphy, M. E., Rebbeck, T. R., Rosenwaks, Z., Levine, A. J., Hu, W. (2009) Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humans. Proc Natl Acad Sci U S A, 106 (24). pp. 9761-6. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Kannabiran, C., Morris, G. F., Mathews, M. B. (1999) Dual action of the adenovirus E1A 243R oncoprotein on the human proliferating cell nuclear antigen promoter: repression of transcriptional activation by p53. Oncogene, 18 (54). pp. 7825-33. ISSN 0950-9232 (Print)

Kim, S. Y., Cordeiro, M. H., Serna, V. A., Ebbert, K., Butler, L. M., Sinha, S., Mills, A. A., Woodruff, T. K., Kurita, T. (2013) Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network. Cell Death and Differentiation, 20 (8). pp. 987-997.

Kirschner, K., Samarajiwa, S. A., Cairns, J. M., Menon, S., Perez-Mancera, P. A., Tomimatsu, K., Bermejo-Rodriguez, C., Ito, Y., Chandra, T., Narita, M., Lyons, S. K., Lynch, A. G., Kimura, H., Ohbayashi, T., Tavare, S., Narita, M. (2015) Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. PLoS Genet, 11 (3). e1005053. ISSN 1553-7390

Kondo, S., Lu, Y., Debbas, M., Lin, A. W., Sarosi, I., Itie, A., Wakeham, A., Tuan, J., Saris, C., Elliott, G., Ma, W. L., Benchimol, S., Lowe, S. W., Mak, T. W., Thukral, S. K. (2003) Characterization of cells and gene-targeted mice deficient for the p53-binding kinase homeodomain-interacting protein kinase 1 (HIPK1). Proceedings of the National Academy of Sciences of the United States of America, 100 (9). pp. 5431-5436. ISSN 0027-8424

Koumenis, C., Alarcon, R., Hammond, E., Sutphin, P., Hoffman, W., Murphy, M., Derr, J., Taya, Y., Lowe, S. W., Kastan, M., Giaccia, A. (2001) Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. Molecular and Cellular Biology, 21 (4). pp. 1297-1310. ISSN 0270-7306

Krizhanovsky, V., Lowe, S. W. (2009) Stem cells: The promises and perils of p53. Nature, 460 (7259). pp. 1085-1086.

L

Laska, M. J., Lowe, S. W., Zender, L., Hearn, S. A., Vogel, U., Jensen, U. B., Bric, A., Nexo, B. A. (2009) Enforced expression of PPP1R13L increases tumorigenesis and invasion through p53-dependent and p53-independent mechanisms. Mol Carcinog, 48 (9). pp. 832-42.

Lin, A. W., Barradas, M., Stone, J. C., Van Aelst, L., Serrano, M., Lowe, S. W. (1998) Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes & Development, 12 (19). pp. 3008-3019. ISSN 0890-9369

Lin, A. W., Lowe, S. W. (2001) Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation. Proceedings of the National Academy of Sciences of the United States of America, 98 (9). pp. 5025-5030. ISSN 0027-8424

Liu, Y., Chen, C., Xu, Z., Scuoppo, C., Rillahan, C. D., Gao, J., Spitzer, B., Bosbach, B., Kastenhuber, E. R., Baslan, T., Ackermann, S., Cheng, L., Wang, Q., Niu, T., Schultz, N., Levine, R. L., Mills, A. A., Lowe, S. W. (2016) Deletions linked to TP53 loss drive cancer through p53-independent mechanisms. Nature, 531 (7595). pp. 471-475. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Lowe, S. W. (1999) Activation of p53 by oncogenes. Endocr Relat Cancer, 6 (1). pp. 45-8. ISSN 1351-0088 (Print)

Lowe, S. W., Lin, A. W. (2000) Apoptosis in cancer. Carcinogenesis, 21 (3). pp. 485-495. ISSN 0143-3334

Lujambio, A., Akkari, L., Simon, J., Grace, D., Tschaharganeh, D. F., Bolden, J. E., Zhao, Z., Thapar, V., Joyce, J. A., Krizhanovsky, V., Lowe, S. W. (2013) Non-cell-autonomous tumor suppression by p53. Cell, 153 (2). pp. 449-460.

M

Ma, O., Cai, W. W., Zender, L., Dayaram, T., Shen, J. H., Herron, A. J., Lowe, S. W., Man, T. K., Lau, C. C., Donehower, L. A. (2009) MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), Amplified on Chromosome 9, Collaborate with p53 Deficiency in Mouse Osteosarcoma Progression. Cancer Res, 69 (6). pp. 2559-2567. ISSN 0008-5472

MacCallum, D. E., Hall, P. A., Wright, E. G. (2001) The TRP53 pathway is induced in vivo by low doses of gamma radiation. Radiation Research, 156 (3). pp. 324-327. ISSN 0033-7587

Macleod, K. F., Sherry, N., Hannon, G., Beach, D., Tokino, T., Kinzler, K., Vogelstein, B., Jacks, T. (1995) p53-Dependent and independent expression of p21 during cell growth, differentiation, and DNA damage. Genes and Development, 9 (8). pp. 935-944. ISSN 08909369

Mayo, L. D., Dixon, J. E., Durden, D. L., Tonks, N. K., Donner, D. B. (2002) PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. Journal of Biological Chemistry, 277 (7). pp. 5484-5489. ISSN 0021-9258

McCurrach, M. E., Connor, T. M., Knudson, C. M., Korsmeyer, S. J., Lowe, S. W. (1997) bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 94 (6). pp. 2345-9. ISSN 0027-8424

Miller, M., Shirole, N., Tian, R., Pal, D., Sordella, R. (2016) The Evolution of TP53 Mutations: From Loss-of-Function to Separation-of-Function Mutants. J Cancer Biol Res, 4 (4). ISSN 2373-9436

Mills, A. A. (2005) p53: link to the past, bridge to the future. Genes Dev, 19 (18). pp. 2091-9. ISSN 0890-9369 (Print)

Mills, A. A., Zheng, B., Wang, X. J., Vogel, H., Roop, D. R., Bradley, A. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature, 398 (6729). pp. 708-713. ISSN 00280836 (ISSN)

Moran, E. (1993) Interaction of adenoviral proteins with pRB and p53. Faseb J, 7 (10). pp. 880-5. ISSN 0892-6638 (Print)

Morris, G. F., Bischoff, J. R., Mathews, M. B. (1996) Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53. Proceedings of the National Academy of Sciences, 93 (2). pp. 895-9. ISSN 0027-8424 (Print)

Murray, S. A., Zheng, H. W., Gu, L., Xiao, Z. X. J. (2003) IGF-1 activates p21 to inhibit UV-induced cell death. Oncogene, 22 (11). pp. 1703-1711. ISSN 0950-9232

N

Naguib, A., Bencze, G., Engle, D. D., Chio, II, Herzka, T., Watrud, K., Bencze, S., Tuveson, D. A., Pappin, D. J., Trotman, L. C. (2014) P53 Mutations Change Phosphatidylinositol Acyl Chain Composition. Cell Reports, 10 (1). pp. 8-19. ISSN 2211-1247

Nakaya, N., Lowe, S. W., Taya, Y., Chenchik, A., Enikolopov, G. (2000) Specific pattern of p53 phosphorylation during nitric oxide-induced cell cycle arrest. Oncogene, 19 (54). pp. 6369-6375. ISSN 0950-9232

O

Okamoto, K., Beach, D. (1994) Cyclin G is a transcriptional target of the p53 tumor suppressor protein. Embo J, 13 (20). pp. 4816-22. ISSN 0261-4189 (Print)

Okamoto, K., Kamibayashi, C., Serrano, M., Prives, C., Mumby, M. C., Beach, D. (1996) p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A. Molecular and Cellular Biology, 16 (11). pp. 6593-602. ISSN 0270-7306

P

Papazoglu, C., Mills, A. A. (2007) p53: At the crossroad between cancer and ageing. Journal of Pathology, 211 (2). pp. 124-133. ISSN 0022-3417

Pardee, T., Zuber, J., Lowe, S. W. (2009) The Flt3 ITD Accelerates An Already Established Myeloid Leukemia and Alters Chemotherapy Response In Vitro and In Vivo in a p53 Dependent Manner. Blood, 114 (22). p. 685. ISSN 0006-4971

Pardee, T. S., Zuber, J., Lowe, S. W. (2011) Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner. Exp Hematol, 39 (4). 473-485 e4. ISSN 1873-2399 (Electronic)0301-472X (Linking)

R

Rocha, S., Soengas, M. S., Lowe, S. W., Glanzmann, C., Fabbro, D., Winterhalter, K., Bodis, S., Pruschy, M. (2000) Protein kinase C inhibitor and irradiation-induced apoptosis: Relevance of the cytochrome c-mediated caspase-9 death pathway. Cell Growth & Differentiation, 11 (9). pp. 491-499. ISSN 1044-9523

Ruppert, J. M., Stillman, B. (1993) Analysis of a protein-binding domain of p53. Mol Cell Biol, 13 (6). pp. 3811-20. ISSN 0270-7306 (Print)

S

Schmitt, C. A., Fridman, J. S., Yang, M., Baranov, E., Hoffman, R. M., Lowe, S. W. (2002) Dissecting p53 tumor suppressor functions in vivo. Cancer Cell, 1 (3). pp. 289-298. ISSN 1535-6108

Schmitt, C. A., Fridman, J. S., Yang, M., Lee, S., Baranov, E., Hoffman, R. M., Lowe, S. W. (2002) A senescence program controlled by p53 and p16(INK4a) contributes to the outcome of cancer therapy. Cell, 109 (3). pp. 335-346. ISSN 0092-8674

Schmitt, C. A., Lowe, S. W. (1999) Apoptosis and therapy. Journal of Pathology, 187 (1). pp. 127-37. ISSN 0022-3417 (Print)

Schmitt, C. A., McCurrach, M. E., de Stanchina, E., Wallace-Brodeur, R. R., Lowe, S. W. (1999) INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes and Development, 13 (20). pp. 2670-7. ISSN 0890-9369 (Print)

Senturk, S., Yao, Z., Camiolo, M., Stiles, B., Rathod, T., Walsh, A. M., Nemajerova, A., Lazzara, M. J., Altorki, N. K., Krainer, A., Moll, U. M., Lowe, S. W., Cartegni, L., Sordella, R. (2014) p53Psi is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proceedings of the National Academy of Sciences of the United States of America, 111 (32). E3287-E3296. ISSN 0027-8424

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Shirole, N. H., Pal, D., Kastenhuber, E. R., Senturk, S., Boroda, J., Pisterzi, P., Miller, M., Munoz, G., Anderluh, M., Ladanyi, M., Lowe, S. W., Sordella, R. (2016) TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions. Elife, 5. ISSN 2050-084X (Electronic)2050-084X (Linking)

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