Items where Subject is "bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function > genes: types > tumor suppressor"

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Number of items at this level: 45.

B

Barretina, J., Taylor, B. S., Banerji, S., Ramos, A. H., Lagos-Quintana, M., Decarolis, P. L., Shah, K., Socci, N. D., Weir, B. A., Ho, A., Chiang, D. Y., Reva, B., Mermel, C. H., Getz, G., Antipin, Y., Beroukhim, R., Major, J. E., Hatton, C., Nicoletti, R., Hanna, M., Sharpe, T., Fennell, T. J., Cibulskis, K., Onofrio, R. C., Saito, T., Shukla, N., Lau, C., Nelander, S., Silver, S. J., Sougnez, C., Viale, A., Winckler, W., Maki, R. G., Garraway, L. A., Lash, A., Greulich, H., Root, D. E., Sellers, W. R., Schwartz, G. K., Antonescu, C. R., Lander, E. S., Varmus, H. E., Ladanyi, M., Sander, C., Meyerson, M., Singer, S. (2010) Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy. Nat Genet, 42 (8). pp. 715-21. ISSN 1546-1718 (Electronic)1061-4036 (Linking)

Berger, A. H., Chen, M., Morotti, A., Janas, J. A., Niki, M., Bronson, R. T., Taylor, B. S., Ladanyi, M., Van Aelst, L., Politi, K., Varmus, H. E., Pandolfi, P. P. (2013) DOK2 inhibits EGFR-mutated lung adenocarcinoma. PLoS One, 8 (11). e79526. ISSN 1932-6203

Biffi, G., Tuveson, D. A. (2017) Cancer: Double trouble for tumours. Nature, 542 (7639). pp. 34-35. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Bolden, J. E., Tasdemir, N., Dow, L. E., van Es, J. H., Wilkinson, J. E., Zhao, Z., Clevers, H., Lowe, S. W. (2014) Inducible In Vivo Silencing of Brd4 Identifies Potential Toxicities of Sustained BET Protein Inhibition. Cell Rep, 8 (6). pp. 1919-1929. ISSN 2211-1247

C

Carnero, A., Hannon, G. J. (1998) The INK4 family of CDK inhibitors. Current Topics in Microbiology and Immunology, 227. pp. 43-55. ISSN 0070-217X (Print)

Chen, C., Liu, Y., Rappaport, A. R., Kitzing, T., Schultz, N., Zhao, Z., Shroff, A. S., Dickins, R. A., Vakoc, C. R., Bradner, J. E., Stock, W., Lebeau, M. M., Shannon, K. M., Kogan, S., Zuber, J., Lowe, S. W. (2014) MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia. Cancer Cell, 25 (5). pp. 652-665. ISSN 1878-3686 (Electronic)1535-6108 (Linking)

Chen, M., Nowak, D. G., Narula, N., Robinson, B., Watrud, K., Ambrico, A., Herzka, T. M., Zeeman, M. E., Minderer, M., Zheng, W., Ebbesen, S. H., Plafker, K. S., Stahlhut, C., Wang, V. M., Wills, L., Nasar, A., Castillo-Martin, M., Cordon-Cardo, C., Wilkinson, J. E., Powers, S., Sordella, R., Altorki, N. K., Mittal, V., Stiles, B. M., Plafker, S. M., Trotman, L. C. (2017) The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. J Cell Biol, 216 (3). pp. 641-656. ISSN 0021-9525

Chen, M. H., Herzka, T. M., Zeeman, M. E., Plafker, K. S., Minderer, M., Castillo-Martin, M., Cordon-Cardo, C., Plafker, S. M., Trotman, L. C. (2013) PTEN levels are controlled by a nuclear transport receptor in lung cancer. Cancer Research, 73 (8 (Sup). p. 5258. ISSN 0008-5472

Chien, Y., Lowe, S. W. (2008) Secreting tumor suppression. Cell, 132 (3). pp. 339-41. ISSN 0092-8674

Cho, Hyejin, Herzka, Tali, Stahlhut, Carlos, Watrud, Kaitlin, Robinson, Brian D., Trotman, Lloyd C. (2015) Rapid in vivo validation of candidate drivers derived from the PTEN-mutant prostate metastasis genome. Methods, 77-78. pp. 197-204. ISSN 1046-2023

D

de Stanchina, E., Lowe, S. W. (2002) Tumour suppression: something for nothing? Nature Cell Biology, 4 (12). E275-E276. ISSN 1465-7392

F

Ferbeyre, G., Lowe, S. W. (2002) Ageing: The price of tumour suppression? Nature, 415 (6867). pp. 26-27. ISSN 0028-0836

H

Halevy, O., Novitch, B. G., Spicer, D. B., Skapek, S. X., Rhee, J., Hannon, G. J., Beach, D., Lassar, A. B. (1995) Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD. Science, 267 (5200). pp. 1018-1021. ISSN 00368075 (ISSN)

Hirao, A., Cheung, A., Duncan, G., Girard, P. M., Elia, A. J., Wakeham, A., Okada, H., Sarkissian, T., Wong, J. A., Sakai, T., de Stanchina, E., Bristow, R. G., Suda, T., Lowe, S. W., Jeggo, P. A., Elledge, S. J., Mak, T. W. (2002) Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Molecular and Cellular Biology, 22 (18). pp. 6521-6532. ISSN 0270-7306

Hu, Q. J., Bautista, C., Edwards, G. M., Defeo-Jones, D., Jones, R. E., Harlow, E. (1991) Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides. Mol Cell Biol, 11 (11). pp. 5792-9. ISSN 0270-7306 (Print)0270-7306 (Linking)

K

Kitzing, T., Xue, W., Roessler, S., Krasnitz, A., Schultz, N., Wang, X. W., Wigler, M., Lowe, S. W. (2012) Cooperating Tumor Suppressor Genes on Chromosome 8p Predict Survival Outcome in Hepatocellular Carcinoma. European Journal of Cancer, 48. S139-S139. ISSN 0959-8049

Kraman, M., Bambrough, P. J., Arnold, J. N., Roberts, E. W., Magiera, L., Jones, J. O., Gopinathan, A., Tuveson, D. A., Fearon, D. T. (2010) Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha. Science, 330 (6005). pp. 827-30. ISSN 1095-9203 (Electronic)0036-8075 (Linking)

L

Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., Parsons, R. (1998) The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Research, 58 (24). pp. 5667-5672. ISSN 0008-5472

Liu, Y., Chen, C., Xu, Z., Scuoppo, C., Rillahan, C. D., Gao, J., Spitzer, B., Bosbach, B., Kastenhuber, E. R., Baslan, T., Ackermann, S., Cheng, L., Wang, Q., Niu, T., Schultz, N., Levine, R. L., Mills, A. A., Lowe, S. W. (2016) Deletions linked to TP53 loss drive cancer through p53-independent mechanisms. Nature, 531 (7595). pp. 471-475. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Lowe, S. (2002) Roles of oncogenes and tumor suppressor genes in apoptosis. European Journal of Cancer, 38. S15-S15. ISSN 0959-8049

Lowe, S. W. (2002) Premature senescence in tumor suppression. Cancer Epidemiology Biomarkers & Prevention, 11 (10). 1259S-1259S. ISSN 1055-9965

M

McCurrach, M. E., Connor, T. M., Knudson, C. M., Korsmeyer, S. J., Lowe, S. W. (1997) bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 94 (6). pp. 2345-9. ISSN 0027-8424

Miething, C., Scuoppo, C., Lindqvist, L., Reyes, J., Ruse, C., Appelmann, I., Yoon, S., Krasnitz, A., Teruya-Feldstein, J., Pappin, D., Pelletier, J., Lowe, S. (2012) An oncogenome-based RNAi screen identifies a tumour suppressor network in B-cell lymphoma relying on the polyamine-hypusine axis. Onkologie, 35. p. 104. ISSN 0378-584X

Moran, E. (1991) Cycles within cycles. Curr Biol, 1 (5). pp. 281-3. ISSN 0960-9822 (Print)0960-9822 (Linking)

Myers, M. P., Tonks, N. K. (1997) PTEN: Sometimes taking it off can be better than putting it on. American Journal of Human Genetics, 61 (6). pp. 1234-1238. ISSN 0002-9297

N

Naguib, A., Bencze, G., Faehnle, C. R., Schalch, T., Lazar, Z., Ruse, C. I., Joshua-Tor, L., Pappin, D. J., Trotman, L. C. (2013) Upstream activation of PTEN. Cancer Research, 73 (8 (Sup). p. 5156. ISSN 0008-5472

O

Okamoto, K., Beach, D. (1994) Cyclin G is a transcriptional target of the p53 tumor suppressor protein. Embo J, 13 (20). pp. 4816-22. ISSN 0261-4189 (Print)

Okamoto, K., Kamibayashi, C., Serrano, M., Prives, C., Mumby, M. C., Beach, D. (1996) p53-dependent association between cyclin G and the B' subunit of protein phosphatase 2A. Molecular and Cellular Biology, 16 (11). pp. 6593-602. ISSN 0270-7306

R

Rappaport, A. R. (2011) Dissecting tumor suppressor and tumor maintenance genes in poor prognosis AML. PhD thesis, Cold Spring Harbor Laboratory.

Rocha, S., Soengas, M. S., Lowe, S. W., Glanzmann, C., Fabbro, D., Winterhalter, K., Bodis, S., Pruschy, M. (2000) Protein kinase C inhibitor and irradiation-induced apoptosis: Relevance of the cytochrome c-mediated caspase-9 death pathway. Cell Growth & Differentiation, 11 (9). pp. 491-499. ISSN 1044-9523

S

Samuelson, A. V., Lowe, S. W. (1997) Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins. Proceedings of the National Academy of Sciences, 94 (22). pp. 12094-9. ISSN 0027-8424 (Print)

Scuoppo, C. (2011) Architectural Models of Tumor Suppression in Lymphoma. PhD thesis, Cold Spring Harbor Laboratory.

Sdek, P., Ying, H. Q., Zheng, H. W., Margulis, A., Tang, X. R., Tian, K., Xiao, Z. X. J. (2004) The central acidic domain of MDM2 is critical in inhibition of retinoblastoma-mediated suppression of E2F and cell growth. Journal of Biological Chemistry, 279 (51). pp. 53317-53322. ISSN 0021-9258

Serrano, M., Lee, H., Chin, L., Cordon-Cardo, C., Beach, D., DePinho, R. A. (1996) Role of the INK4a locus in tumor suppression and cell mortality. Cell, 85 (1). pp. 27-37. ISSN 0092-8674 (Print)

Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., Lowe, S. W. (1997) Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell, 88 (5). pp. 593-602. ISSN 0092-8674 (Print)

Sheltzer, J. (2016) Single-chromosome aneuploidy commonly functions as a tumor suppressor. Molecular Biology of the Cell, 27. A10. ISSN 1059-1524

Sheltzer, Jason M., Ko, Julie H., Replogle, John M., Habibe Burgos, Nicole C., Chung, Erica S., Meehl, Colleen M., Sayles, Nicole M., Passerini, Verena, Storchova, Zuzana, Amon, Angelika (2017) Single-chromosome Gains Commonly Function as Tumor Suppressors. Cancer Cell, 31 (2). pp. 240-255. ISSN 1535-6108

Soengas, M. S., Lowe, S. W. (2000) p53 and p73: seeing double? Nature Genetics, 26 (4). pp. 391-392. ISSN 1061-4036

Streppel, M. M., Lata, S., Delabastide, M., Montgomery, E. A., Wang, J. S., Canto, M. I., Macgregor-Das, A. M., Pai, S., Morsink, F. H., Offerhaus, G. J., Antoniou, E., Maitra, A., McCombie, W. R. (2014) Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett's esophagus. Oncogene, 33 (3). pp. 347-57. ISSN 0950-9232

T

Tonks, N. K., Myers, M. P. (1999) Structural assets of a tumor suppressor. Science, 286 (5447). pp. 2096-2097. ISSN 0036-8075

Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., Huang, C. H., Lechel, A., Andersen, J. B., Capper, D., Zender, L., Longerich, T., Enikolopov, G., Lowe, S. W. (2014) p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer. Cell, 158 (3). pp. 579-92. ISSN 0092-8674

V

Vestin, A., Mills, A. A. (2013) The tumor suppressor Chd5 is induced during neuronal differentiation, in the developing mouse brain. Gene Expression Patterns, 13 (8). pp. 482-489. ISSN 1872-7298 (Electronic)1567-133X (Linking)

W

Wagner, A. J., Malinowska-Kolodziej, I., Morgan, J. A., Qin, W., Fletcher, C. D., Vena, N., Ligon, A. H., Antonescu, C. R., Ramaiya, N. H., Demetri, G. D., Kwiatkowski, D. J., Maki, R. G. (2010) Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors. J Clin Oncol, 28 (5). pp. 835-40. ISSN 1527-7755 (Electronic)0732-183X (Linking)

X

Xiong, Y., Zhang, H., Beach, D. (1993) Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev, 7 (8). pp. 1572-83. ISSN 0890-9369 (Print)

Y

Ying, H. Q., Elpek, K. G., Vinjamoori, A., Zimmerman, S. M., Chu, G. C., Yan, H. Y., Fletcher-Sananikone, E., Zhang, H. L., Liu, Y. C., Wang, W., Ren, X. J., Zheng, H. W., Kimmelman, A. C., Paik, J. H., Lim, C., Perry, S. R., Jiang, S., Malinn, B., Protopopov, A., Colla, S., Xiao, Y. H., Hezel, A. F., Bardeesy, N., Turley, S. J., Wang, Y. A. A., Chin, L., Thayer, S. P., DePinho, R. A. (2011) PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-kappa B-Cytokine Network. Cancer Discovery, 1 (2). pp. 158-169. ISSN 2159-8274

This list was generated on Thu Jun 29 00:02:24 2017 EDT.
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