Items where Subject is "pancreatic cancer"

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Number of items at this level: 157.

A

Aguirre, A. J., Nowak, J. A., Camarda, N. D., Moffitt, R. A., Ghazani, A. A., Hazar-Rethinam, M., Raghavan, S., Kim, J., Brais, L. K., Ragon, D., Welch, M. W., Reilly, E., McCabe, D., Marini, L., Anderka, K., Helvie, K., Oliver, N., Babic, A., Da Silva, A., Nadres, B., Van Seventer, E. E., Shahzade, H. A., St Pierre, J. P., Burke, K. P., Clancy, T. E., Cleary, J. M., Doyle, L. A., Jajoo, K., McCleary, N. J., Meyerhardt, J. A., Murphy, J. E., Ng, K., Patel, A. K., Perez, K., Rosenthal, M. H., Rubinson, D. A., Ryou, M., Shapiro, G. I., Sicinska, E., Silverman, S. G., Nagy, R. J., Lanman, R. B., Knoerzer, D., Welsch, D. J., Yurgelun, M. B., Fuchs, C. S., Garraway, L. A., Getz, G., Hornick, J. L., Johnson, B. E., Kulke, M. H., Mayer, R. J., Miller, J. W., Shyn, P. B., Tuveson, D. A., Wagle, N., Yeh, J. J., Hahn, W. C., Corcoran, R. B., Carter, S. L., Wolpin, B. M. (June 2018) Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine. Cancer Discov, 8 (9). pp. 1096-1111. ISSN 2159-8274

Almeida, Ana S, Kees, Tim, Egeblad, Mikala (October 2015) Modulating innate-adaptive immune cell interactions to achieve tumor rejection. In: AACR Special Conference: Tumor Immunology and Immunotherapy: A New Chapter.

B

Baker, L. A., Tiriac, H., Tuveson, D. A. (2019) Generation and Culture of Human Pancreatic Ductal Adenocarcinoma Organoids from Resected Tumor Specimens. Methods Mol Biol, 1882. pp. 97-115. ISSN 1064-3745

Baker, L. A., Tuveson, D. A. (2019) Generation and Culture of Tumor and Metastatic Organoids from Murine Models of Pancreatic Ductal Adenocarcinoma. Methods Mol Biol, 1882. pp. 117-133. ISSN 1064-3745

Baker, Lindsey A., Tiriac, Hervé, Clevers, Hans, Tuveson, David A. (April 2016) Modeling Pancreatic Cancer with Organoids. Trends in Cancer, 2 (4). pp. 176-190. ISSN 2405-8033

Balachandran, V. P., Luksza, M., Zhao, J. N., Makarov, V., Moral, J. A., Remark, R., Herbst, B., Askan, G., Bhanot, U., Senbabaoglu, Y., Wells, D. K., Cary, C. I. O., Grbovic-Huezo, O., Attiyeh, M., Medina, B., Zhang, J., Loo, J., Saglimbeni, J., Abu-Akeel, M., Zappasodi, R., Riaz, N., Smoragiewicz, M., Kelley, Z. L., Basturk, O., Gonen, M., Levine, A. J., Allen, P. J., Fearon, D. T., Merad, M., Gnjatic, S., Iacobuzio-Donahue, C. A., Wolchok, J. D., DeMatteo, R. P., Chan, T. A., Greenbaum, B. D., Merghoub, T., Leach, S. D. (November 2017) Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer. Nature, 551 (7681). pp. 512-516. ISSN 0028-0836

Balachandran, Vinod, Luksza, Marta, Zhao, Julia N, Makarov, Vladimir, Moral, John Alec, Remark, Romain, Herbst, Brian, Askan, Gokce, Bhanot, Umeshkumar, Senbabaoglu, Yasin, Wells, Danny, Cary, Charles Ian Ormsby, Grbovic-Huezo, Olivera, Attiyeh, Marc, Medina, Benjamin, Zhang, Jennifer, Loo, Jennifer, Saglimbeni, Joseph, Abu-Akeel, Mohsen, Zappasodi, Roberta, Riaz, Nadeem, Smoragiewicz, Martin, Basturk, Olca, Gonen, Mithat, Levine, Arnold J, Allen, Peter J, Fearon, Douglas T, Merad, Miriam, Gnjatic, Sacha, Iacobuzio-Donahue, Christine, Wolchok, Jedd, DeMatteo, Ronald, Greenbaum, Benjamin, Merghoub, Taha, Leach, Steven (November 2017) Identification of unique neoantigen qualities in long-term pancreatic cancer survivors. In: UNSPECIFIED.

Bapiro, T. E., Frese, K. K., Courtin, A., Bramhall, J. L., Madhu, B., Cook, N., Neesse, A., Griffiths, J. R., Tuveson, D. A., Jodrell, D. I., Richards, F. M. (May 2014) Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo. British Journal of Cancer, 111 (2). pp. 318-325. ISSN 0007-0920

Baumgart, S., Chen, N. M., Siveke, J. T., Konig, A., Zhang, J. S., Singh, S. K., Wolf, E., Bartkuhn, M., Esposito, I., Hessmann, E., Reinecke, J., Nikorowitsch, J., Brunner, M., Singh, G., Fernandez-Zapico, M. E., Smyrk, T., Bamlet, W. R., Eilers, M., Neesse, A., Gress, T. M., Billadeau, D. D., Tuveson, D., Urrutia, R., Ellenrieder, V. (June 2014) Inflammation-Induced NFATc1-STAT3 Transcription Complex Promotes Pancreatic Cancer Initiation by Kras(G12D). Cancer Discovery, 4 (6). pp. 688-701. ISSN 2159-8274

Biasci, D., Smoragiewicz, M., Connell, C. M., Wang, Z., Gao, Y., Thaventhiran, J. E., Basu, B., Magiera, L., Johnson, I. T., Bax, L., Gopinathan, A., Isherwood, C., Gallagher, F., Pawula, M., Hudecova, I., Gale, D., Rosenfeld, N., Barmpounakis, P., Popa, E. C., Brais, R., Godfrey, E., Mir, F., Richards, F., Fearon, D. T., Janowitz, T., Jodrell, D. (July 2020) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. medRxiv. (Unpublished)

Biffi, G., Ohlund, D., Tuveson, D. (August 2016) Building up the tension between the epithelial and stromal compartment in pancreatic ductal adenocarcinoma. Cell Death Differ, 23 (8). pp. 1265-1266. ISSN 1476-5403 (Electronic)1350-9047 (Linking)

Biffi, G., Oni, T. E., Spielman, B., Hao, Y., Elyada, E., Park, Y., Preall, J., Tuveson, D. A. (October 2018) IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma. Cancer Discov, 9 (2). pp. 282-301. ISSN 2159-8274

Biffi, G., Tuveson, D. A. (February 2017) Cancer: Double trouble for tumours. Nature, 542 (7639). pp. 34-35. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Biffi, G., Tuveson, D. A. (May 2019) A FATal Combination: Fibroblast-Derived Lipids and Cancer-Derived Autotaxin Promote Pancreatic Cancer Growth. Cancer Discov, 9 (5). pp. 578-580. ISSN 2159-8274

Boj, S. F., Hwang, C. I., Baker, L. A., Engle, D. D., Tuveson, D. A., Clevers, H. (January 2016) Model organoids provide new research opportunities for ductal pancreatic cancer. Mol Cell Oncol, 3 (1). e1014757. ISSN 2372-3556 (Electronic)2372-3556 (Linking)

Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A, Chio, Iok In Christine, Engle, Dannielle D, Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S, Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H, van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D, Wilson, John P, Feigin, Michael E, Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M, Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N, Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H M., Molenaar, I.  Quintus, Borel Rinkes, Inne H, Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J, Iacobuzio-Donahue, Christine, Leach, Steven D, Pappin, Darryl J, Hammell, Molly, Klimstra, David S, Basturk, Olca, Hruban, Ralph H, Offerhaus, George Johan, Vries, Robert G J., Clevers, Hans, Tuveson, David A (January 2015) Organoid Models of Human and Mouse Ductal Pancreatic Cancer. Cell, 160 (1-2). pp. 324-338. ISSN 0092-8674

Bott, A. J., Shen, J., Tonelli, C., Zhan, L., Sivaram, N., Jiang, Y. P., Yu, X., Bhatt, V., Chiles, E., Zhong, H., Maimouni, S., Dai, W., Velasquez, S., Pan, J. A., Muthalagu, N., Morton, J., Anthony, T. G., Feng, H., Lamers, W. H., Murphy, D. J., Guo, J. Y., Jin, J., Crawford, H. C., Zhang, L., White, E., Lin, R. Z., Su, X., Tuveson, D. A., Zong, W. X. (October 2019) Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism. Cell Rep, 29 (5). 1287-1298.e6.

Bradley, Sherille D, Talukder, Amjad H, Lai, Ivy, Davis, Rebecca, Alvarez, Hector, Tiriac, Herve, Zhang, Minying, Chiu, Yulun, Melendez, Brenda, Jackson, Kyle R, Katailiha, Arjun, Sonnemann, Heather M, Li, Fenge, Kang, Yaan, Qiao, Na, Pan, Bih-Fang, Lorenzi, Philip L, Hurd, Mark, Mittendorf, Elizabeth A, Peterson, Christine B, Javle, Milind, Bristow, Christopher, Kim, Michael, Tuveson, David A, Hawke, David, Kopetz, Scott, Wolff, Robert A, Hwu, Patrick, Maitra, Anirban, Roszik, Jason, Yee, Cassian, Lizée, Gregory (October 2020) Vestigial-like 1 is a shared targetable cancer-placenta antigen expressed by pancreatic and basal-like breast cancers. Nature Communications, 11 (1). p. 5332. ISSN 2041-1723

Buscaglia, Jonathan M., Bucobo, Juan Carlos, Tiriac, Herve, Tzimas, Demetrios, Grewal, Suman, LaComb, Joseph, Rowehl, Leahana, Nagula, Satish, Wu, Maoxin, Kim, Joseph, Sasson, Aaron, Li, Ellen, Young, Candice M., Tuveson, David A. (May 2017) 111 Successful Creation of Pancreatic Cancer Organoids By Means of Eus-Guided Fine-Needle Biopsy (EUS-FNB) for Personalized Cancer Treatment. Gastrointestinal Endoscopy, 85 (5, Sup). AB50-AB51. ISSN 0016-5107

C

Carapua, E. F., Gemenetzidis, E., Feig, C., Tuveson, D., Kocher, H. (July 2015) Developing drug combinations to co-target pancreatic cancer and its supporting stroma. Cancer Research, 75 (Supple). B72. ISSN 0008-5472

Chan, K., Robert, F., Oertlin, C., Kapeller-Libermann, D., Avizonis, D., Gutierrez, J., Handly-Santana, A., Doubrovin, M., Park, J., Schoepfer, C., Da Silva, B., Yao, M., Gorton, F., Shi, J., Thomas, C. J., Brown, L. E., Porco, J. A., Pollak, M., Larsson, O., Pelletier, J., Chio, I. I. C. (November 2019) eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma. Nat Commun, 10 (1). p. 5151. ISSN 2041-1723

Chan-Seng-Yue, M., Kim, J. C., Wilson, G. W., Ng, K., Figueroa, E. F., O'Kane, G. M., Connor, A. A., Denroche, R. E., Grant, R. C., McLeod, J., Wilson, J. M., Jang, G. H., Zhang, A., Liang, S. B., Borgida, A., Chadwick, D., Kalimuthu, S., Lungu, I., Bartlett, J. M. S., Krzyzanowski, P. M., Sandhu, V., Tiriac, H., Froeling, F. E. M., Karasinska, J. M., Topham, J. T., Renouf, D. J., Schaeffer, D. F., Jones, S. J. M., Marra, M. A., Laskin, J., Chetty, R., Stein, L. D., Zogopoulos, G., Haibe-Kains, B., Campbell, P. J., Tuveson, D. A., Knox, J. J., Fischer, S. E., Gallinger, S., Notta, F. (January 2020) Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution. Nat Genet. ISSN 1061-4036 (Public Dataset)

Chen, S., Auletta, T., Dovirak, O., Hutter, C., Kuntz, K., El-Ftesi, S., Kendall, J., Han, H., Von Hoff, D. D., Ashfaq, R., Maitra, A., Iacobuzio-Donahue, C. A., Hruban, R. H., Lucito, R. (November 2008) Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification. Cancer Biol Ther, 7 (11). pp. 1793-1802.

Cheng, D., Tuveson, D. (January 2018) Kras in Organoids. Cold Spring Harb Perspect Med, 8 (10). ISSN 2157-1422

Cheng, D. K., Oni, T. E., Park, Y., Thalappillil, J. S, Ting, H.-C., Alagesan, B., Prasad, N. V., Rivera, K. D., Pappin, D. J., Van Aelst, L., Tuveson, D. A. (September 2020) Oncogenic KRAS engages an RSK1/NF1 complex in pancreatic cancer. BioRxiv. (Unpublished)

Cheng, Derek K, Oni, Tobiloba E, Thalappillil, Jennifer S, Park, Youngkyu, Ting, Hsiu-Chi, Alagesan, Brinda, Prasad, Nadia V, Addison, Kenneth, Rivera, Keith D, Pappin, Darryl J, Van Aelst, Linda, Tuveson, David A (May 2021) Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proceedings of the National Academy of Sciences of USA, 118 (21). e2016904118-e2016904118. ISSN 0027-8424

Cheung, E. C., DeNicola, G. M., Nixon, C., Blyth, K., Labuschagne, C. F., Tuveson, D. A., Vousden, K. H. (January 2020) Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. ISSN 1535-6108

Chio, I. I. C., Jafarnejad, S. M., Ponz-Sarvise, M., Park, Y., Rivera, K., Palm, W., Ohlund, D., Hammell, M., Crawford, H., Schmidt, E., Thompson, C., Pappin, D., Sonenberg, N., Tuveson, D. (March 2017) NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer. Cancer Research, 77 (Supple). ISSN 0008-54721538-7445

Chio, II, Tuveson, D. A. (January 2017) ROS in translation: Chink in the armor. Cell Cycle, 16 (4). pp. 297-298. ISSN 1551-4005

Chio, Iok In Christine, Jafarnejad, Seyed Mehdi, Ponz-Sarvise, Mariano, Park, Youngkyu, Rivera, Keith, Palm, Wilhelm, Wilson, John, Sangar, Vineet, Hao, Yuan, Öhlund, Daniel, Wright, Kevin, Filippini, Dea, Lee, Eun Jung, Da Silva, Brandon, Schoepfer, Christina, Wilkinson, John Erby, Buscaglia, Jonathan M, DeNicola, Gina M, Tiriac, Herve, Hammell, Molly, Crawford, Howard C, Schmidt, Edward E, Thompson, Craig B, Pappin, Darryl J, Sonenberg, Nahum, Tuveson, David A (August 2016) NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell, 166 (4). pp. 963-976. ISSN 0092-8674

Connell, Claire M, Brais, Rebecca, Whitaker, Hayley, Upponi, Sara, Beh, Ian, Risdall, Jane, Corrie, Pippa, Janowitz, Tobias, Jodrell, Duncan I (January 2020) Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report. BMC Cancer, 20 (1). p. 38. ISSN 1471-2407

Cook, N., Basu, B., Smith, D. M., Gopinathan, A., Evans, J., Steward, W. P., Palmer, D., Propper, D., Venugopal, B., Hategan, M., Anthoney, D. A., Hampson, L. V., Nebozhyn, M., Tuveson, D., Farmer-Hall, H., Turner, H., McLeod, R., Halford, S., Jodrell, D. (March 2018) A phase I trial of the gamma-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma. Br J Cancer, 118 (6). pp. 793-801. ISSN 0007-0920

Cook, N., Frese, K. K., Bapiro, T. E., Jacobetz, M. A., Gopinathan, A., Miller, J. L., Rao, S. S., Demuth, T., Howat, W. J., Jodrell, D. I., Tuveson, D. A. (March 2012) Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma. J Exp Med, 209 (3). pp. 437-44. ISSN 1540-9538 (Electronic)0022-1007 (Linking)

Corrie, P., Qian, W., Gopinathan, A., Williams, M., Brais, R., Valle, J. W., Basu, B., Falk, S., Iwuji, C., Wasan, H., Palmer, D., Scott-Brown, M., Wadsley, J., Arif, S., Bax, L., Bundi, P., Skells, R., Neesse, A., Tuveson, D., Jodrell, D. (September 2017) Strong tumour cytidine deaminase (CDA) staining predicts for improved survival associated with sequential nab-Paclitaxel (nabP) and gemcitabine (GEM) chemotherapy as first line treatment of patients (pts) with metastatic pancreatic adenocarcinoma (mPDAC). Annals of Oncology, 28 (Supple). 73P. ISSN 0923-7534

Corrie, P.G., Qian, W., Basu, B., Valle, J.W., Falk, S., Lwuji, C., Wasan, H., Palmer, D., Scott-Brown, M., Wadsley, J., Arif, S., Bridgewater, J., Propper, D., Gillmore, R., Gopinathan, A., Skells, R., Bundi, P., Brais, R., Dalchau, K., Bax, L., Chhabra, A., Machin, A., Dayim, A., McAdam, K., Cummins, S., Wall, L., Ellis, R., Anthoney, A., Evans, J., Ma, Y.T., Isherwood, C., Neesse, A., Tuveson, D., Jodrell, D. I. (April 2020) Scheduling Nab-Paclitaxel Combined With Gemcitabine as First-Line Treatment for Metastatic Pancreatic Adenocarcinoma. Br J Cancer. ISSN 0007-0920

D

Davies, C. C., Harvey, E., McMahon, R. F. T., Finegan, K. G., Connor, F., Davis, R. J., Tuveson, D. A., Tournier, C. (April 2014) Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Cancer Research, 74 (12). pp. 3344-3356. ISSN 15387445

Dent, P., Booth, L., Roberts, J. L., Liu, J., Poklepovic, A., Lalani, A. S., Tuveson, D., Martinez, J., Hancock, J. F. (June 2019) Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. Oncogene. ISSN 0950-9232

Dreyer, Stephan B, Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc, Moran-Jones, Kim, Wright, Derek W, Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J, McGregor, Grant A, Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L, Candido, Juliana, Balkwill, Frances, Barry, Simon T, Grützmann, Robert, Rahib, Lola, Glasgow Precision Oncology Laboratory,, , Australian Pancreatic Cancer Genome Initiative, , Johns, Amber, Pajic, Marina, Froeling, Fieke EM, Beer, Phillip, Musgrove, Elizabeth A, Petersen, Gloria M, Ashworth, Alan, Frame, Margaret C, Crawford, Howard C, Simeone, Diane M, Lord, Chris, Mukhopadhyay, Debabrata, Pilarsky, Christian, Tuveson, David A, Cooke, Susanna L, Jamieson, Nigel B, Morton, Jennifer P, Sansom, Owen J, Bailey, Peter J, Biankin, Andrew V, Chang, David K (January 2021) Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer. Gastroenterology, 160 (1). 362-377.e13. ISSN 0016-5085

E

Eberl, M., Klingler, S., Mangelberger, D., Loipetzberger, A., Damhofer, H., Zoidl, K., Schnidar, H., Hache, H., Bauer, H. C., Solca, F., Hauser-Kronberger, C., Ermilov, A. N., Verhaegen, M. E., Bichakjian, C. K., Dlugosz, A. A., Nietfeld, W., Sibilia, M., Lehrach, H., Wierling, C., Aberger, F. (2012) Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells. EMBO Molecular Medicine, 4 (3). pp. 218-233. ISSN 17574676 (ISSN)

Ebine, K., Kumar, K., Pham, T. N., Shields, M. A., Collier, K. A., Shang, M., DeCant, B. T., Urrutia, R., Hwang, R. F., Grimaldo, S., Principe, D. R., Grippo, P. J., Bentrem, D. J., Munshi, H. G. (September 2018) Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells. Sci Rep, 8 (1). p. 13225. ISSN 2045-2322

Engle, D., Tiriac, H., Pommier, A., Schoepfer, C., Da Silva, B., Yao, M., Park, Y., Hollingsworth, M. A., Tuveson, D. (May 2018) Exploring the role of glycosylation in pancreatic diseass. Cancer Research, 78 (10 Sup). p. 44. ISSN 0008-5472

Engle, D. D., Tiriac, H., Rivera, K. D., Pommier, A., Whalen, S., Oni, T. E., Alagesan, B., Lee, E. J., Yao, M. A., Lucito, M. S., Spielman, B., Da Silva, B., Schoepfer, C., Wright, K., Creighton, B., Afinowicz, L., Yu, K. H., Grutzmann, R., Aust, D., Gimotty, P. A., Pollard, K. S., Hruban, R. H., Goggins, M. G., Pilarsky, C., Park, Y., Pappin, D. J., Hollingsworth, M. A., Tuveson, D. A. (June 2019) The glycan CA19-9 promotes pancreatitis and pancreatic cancer in mice. Science, 364 (6446). pp. 1156-1162. ISSN 0036-8075

F

Fearon, Douglas, Wang, Zhikai (September 2020) Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy. In: Proceedings of the AACR Virtual Special Conference on Pancreatic Cancer; 2020.

Fearon, Douglas T, Janowitz, Tobias (March 2021) AMD3100/Plerixafor overcomes immune inhibition by the CXCL12-KRT19 coating on pancreatic and colorectal cancer cells. British Journal of Cancer. ISSN 0007-0920

Feig, C., Gopinathan, A., Neesse, A., Chan, D. S., Cook, N., Tuveson, D. A. (August 2012) The pancreas cancer microenvironment. Clin Cancer Res, 18 (16). pp. 4266-76. ISSN 1078-0432 (Print)1078-0432 (Linking)

Feig, C., Jones, J. O., Kraman, M., Wells, R. J. B., Deonarine, A., Chan, D. S., Connell, C. M., Roberts, E. W., Zhao, Q., Caballero, O. L., Teichmann, S. A., Janowitz, T., Jodrell, D. I., Tuveson, D. A., Fearon, D. T. (December 2013) Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 110 (50). pp. 20212-20217. ISSN 00278424 (ISSN)

Feigin, M. E., Garvin, T., Bailey, P., Waddell, N., Chang, D. K., Kelley, D. R., Shuai, S., Gallinger, S., McPherson, J. D., Grimmond, S. M., Khurana, E., Stein, L. D., Biankin, A. V., Schatz, M. C., Tuveson, D. A. (June 2017) Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma. Nat Genet, 49 (6). pp. 825-833. ISSN 1061-4036

Feigin, M. E., Tuveson, D. A. (2016) Challenges and Opportunities in Modeling Pancreatic Cancer. Cold Spring Harb Symp Quant Biol, 81. pp. 231-235. ISSN 0091-7451

Feigin, M. E., Tuveson, D. A. (April 2017) Organoid models to interrogate GPCR regulation of pancreatic tumorigenesis. Faseb Journal, 31 (Supple). Meeting Abstract: lb524 . ISSN 0892-6638

Frese, K. K., Neesse, A., Cook, N., Bapiro, T. E., Lolkema, M. P., Jodrell, D. I., Tuveson, D. A. (March 2012) nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer. Cancer Discov, 2 (3). pp. 260-9. ISSN 2159-8290 (Electronic)2159-8274 (Linking)

Froeling, F., Tuveson, D. (May 2018) Pancreatic cancer foiled by a switch of tumour subtype. Nature, 557 (7706). pp. 500-501. ISSN 0028-0836

Froeling, F. E. M., Mosur Swamynathan, M., Deschenes, A., Chio, I. I. C., Brosnan, E., Yao, M. A., Alagesan, P., Lucito, M. S., Li, J., Chang, A. Y., Trotman, L. C., Belleau, P., Park, Y., Rogoff, H. A., Watson, J. D., Tuveson, D. A. (September 2019) Bioactivation of napabucasin triggers reactive oxygen species-mediated cancer cell death. Clin Cancer Res, 25 (23). pp. 7162-7174. ISSN 1078-0432 (Print)1078-0432

Froeling, Fieke E.M., Plenker, Dennis, O’Kane, Grainne, Aguirre, Andrew J., Wolpin, Brian M., Laheru, Daniel A., Saif, M Wasif, Yu, Kenneth H., Fischer, Sandra, Gallinger, Steven, Knox, Jennifer J., Jaffee, Elizabeth M., Tuveson, David A. (September 2020) Organoid Personalized Therapeutics and the Pancreatic Adenocarcinoma Signature Stratification for treatment (PASS) – 01 trial. In: The London Pancreas Workshop 2020.

G

Gao, ChongFeng, Wisniewski, Luke, Liu, Ying, Staal, Ben, Beddows, Ian, Plenker, Dennis, Aldakkak, Mohammed, Hall, Johnathan, Barnett, Daniel, Gouda, Mirna Kheir, Allen, Peter, Drake, Richard, Zureikat, Amer, Huang, Ying, Evans, Douglas, Singhi, Aatur, Brand, Randall, Tuveson, David, Tsai, Susan, Haab, Brian (September 2020) Detection of chemotherapy-resistant pancreatic cancer using a glycan Biomarker. In: AACR Virtual Special Conference on Pancreatic Cancer.

Gao, ChongFeng, Wisniewski, Luke, Liu, Ying, Staal, Ben, Beddows, Ian, Plenker, Dennis, Aldakkak, Mohammed, Hall, Johnathan, Barnett, Daniel, Gouda, Mirna Kheir, Allen, Peter, Drake, Richard, Zureikat, Amer, Huang, Ying, Evans, Douglas, Singhi, Aatur, Brand, Randall E, Tuveson, David A, Tsai, Susan, Haab, Brian B (January 2021) Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA. Clinical Cancer Research, 27 (1). pp. 226-236. ISSN 1078-0432

H

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Rosati, A., Basile, A., D'Auria, R., d'Avenia, M., De Marco, M., Falco, A., Festa, M., Guerriero, L., Iorio, V., Parente, R., Pascale, M., Marzullo, L., Franco, R., Arra, C., Barbieri, A., Rea, D., Menichini, G., Hahne, M., Bijlsma, M., Barcaroli, D., Sala, G., di Mola, F. F., di Sebastiano, P., Todoric, J., Antonucci, L., Corvest, V., Jawhari, A., Firpo, M. A., Tuveson, D. A., Capunzo, M., Karin, M., De Laurenzi, V., Turco, M. C. (November 2015) BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages. Nat Commun, 6. p. 8695. ISSN 2041-1723 (Electronic)2041-1723 (Linking)

Rosati, A., Basile, A., D'Auria, R., d'Avenia, M., De Marco, M., Falco, A., Festa, M., Guerriero, L., Iorio, V., Pascale, M., Franco, R., Arra, C., Barbieri, A., Rea, D., Menichini, G., Hahne, M., Bijlsma, M., Barcaroli, D., Tuveson, D. A., Todoric, J., Karin, M., De Laurenzi, V., Turco, M. C. (August 2015) PDAC cells release BAG3 that activates a paracrine loop with stromal macrophages. Cancer Research, 75 (Supple). Abstract 2393. ISSN 0008-5472

Roy, I., McAllister, D., Gorse, E., Dixon, K., Cheng, G., Getschman, A., Engle, D., Tsai, S., Tuveson, D., Evans, D., Volkman, B., Kalyanaraman, B., Dwinell, M. (July 2015) Chemokine biased agonists regulate pancreatic cancer migration and metastasis through bioenergetic signaling. Cancer Research, 75 (Supple). B55. ISSN 0008-5472

Roy, I., McAllister, D. M., Gorse, E., Dixon, K., Piper, C. T., Zimmerman, N. P., Getschman, A. E., Tsai, S., Engle, D. D., Evans, D. B., Volkman, B. F., Kalyanaraman, B., Dwinell, M. B. (September 2015) Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling. Cancer Res, 75 (17). pp. 3529-42. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

S

Saiyin, H., Ardito-Abraham, C. M., Wu, Y., Wei, Y., Fang, Y., Han, X., Li, J., Zhou, P., Yi, Q., Maitra, A., Liu, J. O., Tuveson, D. A., Lou, W., Yu, L. (June 2015) Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma. J Pathol, 236 (2). pp. 142-154. ISSN 0022-3417

Salas-Benito, D., Melero, I., Ponz-Sarvise, M. (July 2019) Vaccination for pancreatic ductal adenocarcinoma: a hard nut to crack. Clin Cancer Res, 25 (18). pp. 5435-5437. ISSN 1078-0432 (Print)1078-0432

Schlomann, U., Koller, G., Conrad, C., Ferdous, T., Golfi, P., Garcia, A. M., Hofling, S., Parsons, M., Costa, P., Soper, R., Bossard, M., Hagemann, T., Roshani, R., Sewald, N., Ketchem, R. R., Moss, M. L., Rasmussen, F. H., Miller, M. A., Lauffenburger, D. A., Tuveson, D. A., Nimsky, C., Bartsch, J. W. (2015) ADAM8 as a drug target in pancreatic cancer. Nature Communications, 6. p. 6175. ISSN 2041-1723

Seifert, L., Werba, G., Tiwari, S., Giao Ly, N. N., Alothman, S., Alqunaibit, D., Avanzi, A., Barilla, R., Daley, D., Greco, S. H., Torres-Hernandez, A., Pergamo, M., Ochi, A., Zambirinis, C. P., Pansari, M., Rendon, M., Tippens, D., Hundeyin, M., Mani, V. R., Hajdu, C., Engle, D., Miller, G. (April 2016) The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature, 532 (7598). pp. 245-9. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Seppala, Toni T, Zimmerman, Jacquelyn W, Rozich, Noah, Blair, Alex, Javed, Ammar, Cameron, John L, Burns, William R, He, Jin, Tuveson, David, Wolfgang, Christopher L, Ryan, David P, Kimmelman, Alec, Herman, Joseph M, Messersmith, Wells, Hong, Theodore S, Ting, David T, Burkhart, Richard Andrew (August 2020) Patient-derived organoids may facilitate precision medicine in pancreatic cancer: Demonstrating feasibility in the context of a multi-center clinical trial. In: AACR Annual Meeting.

Seppälä, Toni T, Zimmerman, Jacquelyn W, Sereni, Elisabetta, Plenker, Dennis, Suri, Reecha, Rozich, Noah, Blair, Alex, Thomas, Dwayne L, Teinor, Jonathan, Javed, Ammar, Patel, Hardik, Cameron, John L, Burns, William R, He, Jin, Tuveson, David A, Jaffee, Elizabeth M, Eshleman, James, Szabolcs, Annamaria, Ryan, David P, Ting, David T, Wolfgang, Christopher L, Burkhart, Richard A (September 2020) Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer. Annals of Surgery, 272 (3). pp. 427-435. ISSN 0003-4932

Serrao, E. M., Kettunen, M. I., Rodrigues, T. B., Dzien, P., Wright, A. J., Gopinathan, A., Gallagher, F. A., Lewis, D. Y., Frese, K. K., Almeida, J., Howat, W. J., Tuveson, D. A., Brindle, K. M. (March 2016) MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model. Gut, 65 (3). pp. 465-75. ISSN 1468-3288 (Electronic)0017-5749 (Linking)

Sherman, Mara H, Yu, Ruth T, Engle, Dannielle D, Ding, Ning, Atkins, Annette R, Tiriac, Herve, Collisson, Eric A, Connor, Frances, Van Dyke, Terry, Kozlov, Serguei, Martin, Philip, Tseng, Tiffany W, Dawson, David W, Donahue, Timothy R, Masamune, Atsushi, Shimosegawa, Tooru, Apte, Minoti V, Wilson, Jeremy S, Ng, Beverly, Lau, Sue Lynn, Gunton, Jenny E, Wahl, Geoffrey M, Hunter, Tony, Drebin, Jeffrey A, O’Dwyer, Peter J, Liddle, Christopher, Tuveson, David A, Downes, Michael, Evans, Ronald M (September 2014) Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy. Cell, 159 (1). pp. 80-93. ISSN 0092-8674

Shields, M., Maguin, P., Giuliano, C., Dallas, S., Wilkinson, J. E., Egeblad, M. (May 2018) Lysyl oxidases suppress pancreatic cancer progression and inhibit FAK and ERK signaling. Cancer Research, 78 (10 Sup). pp. 76-77. ISSN 0008-5472

Shields, M. A., Maguin, P., Kumar, P., Dallas, S. L., Egeblad, M. (July 2015) Lysyl oxidases are poor therapeutic targets in pancreatic cancer. Cancer Research, 75 (Supple). A43. ISSN 0008-5472

Somerville, T. D. D., Xu, Y., Miyabayashi, K., Tiriac, H., Cleary, C. R., Maia-Silva, D., Milazzo, J. P., Tuveson, D. A., Vakoc, C. R. (November 2018) TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma. Cell Rep, 25 (7). 1741-1755.e7. ISSN 2211-1247 (Public Dataset)

Somerville, T. D. D., Biffi, G., DaBler-Plenker, J., Hur, S.K., He, X.-Y., Vance, K.E., Miyabayashi, K., Xu, Y., Maia-Silva, D., Klingbeil, O., Demerdash, O. E., Preall, J. B., Hollingsworth, M. A., Egeblad, M., Tuveson, D. A., Vakoc, C. R. (April 2020) Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. Elife, 9. e53381. ISSN 2050-084x (Public Dataset)

Somerville, T. D. D., Xu, Y., Wu, X. S., Maia-Silva, D., Hur, S. K., de Almeida, L. M. N., Preall, J. B., Koo, P. K., Vakoc, C. R. (May 2020) ZBED2 is an antagonist of interferon regulatory factor 1 and modifies cell identity in pancreatic cancer. Proc Natl Acad Sci U S A, 117 (21). pp. 11471-11482. ISSN 0027-8424 (Print)0027-8424

Steele, Nina G, Biffi, Giulia, Kemp, Samantha B, Zhang, Yaqing, Drouillard, Donovan, Syu, LiJyun, Hao, Yuan, Oni, Tobiloba E, Brosnan, Erin, Elyada, Ela, Doshi, Abhishek, Hansma, Christa, Espinoza, Carlos, Abbas, Ahmed, The, Stephanie, Irizarry-Negron, Valerie, Halbrook, Christopher J, Franks, Nicole E, Hoffman, Megan T, Brown, Kristee, Carpenter, Eileen S, Nwosu, Zeribe C, Johnson, Craig, Lima, Fatima, Anderson, Michelle A, Park, Youngkyu, Crawford, Howard C, Lyssiotis, Costas A, Frankel, Timothy L, Rao, Arvind, Bednar, Filip, Dlugosz, Andrzej A, Preall, Jonathan B, Tuveson, David A, Allen, Benjamin L, Pasca di Magliano, Marina (April 2021) Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer. Clinical Cancer Research, 27 (7). pp. 2023-2037. ISSN 1078-0432

Sugarman, R., Patel, R., Sharma, S., Plenker, D., Tuveson, D., Saif, M. W. (July 2019) Pharmacokinetics and pharmacodynamics of new drugs for pancreatic cancer. Expert Opin Drug Metab Toxicol, 15 (7). pp. 541-552. ISSN 1742-5255

T

Tamura, K., Yu, J., Hata, T., Suenaga, M., Shindo, K., Abe, T., MacGregor-Das, A., Borges, M., Wolfgang, C. L., Weiss, M. J., He, J., Canto, M. I., Petersen, G. M., Gallinger, S., Syngal, S., Brand, R. E., Rustgi, A., Olson, S. H., Stoffel, E., Cote, M. L., Zogopoulos, G., Potash, J. B., Goes, F. S., McCombie, R. W., Zandi, P. P., Pirooznia, M., Kramer, M., Parla, J., Eshleman, J. R., Roberts, N. J., Hruban, R. H., Klein, A. P., Goggins, M. (May 2018) Mutations in the pancreatic secretory enzymes CPA1 and CPB1 are associated with pancreatic cancer. Proc Natl Acad Sci U S A, 115 (18). pp. 4767-4772. ISSN 0027-8424

Tian, C., Clauser, K. R., Ohlund, D., Rickelt, S., Huang, Y., Gupta, M., Mani, D. R., Carr, S. A., Tuveson, D. A., Hynes, R. O. (September 2019) Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cells. Proc Natl Acad Sci U S A, 116 (39). pp. 19609-19618. ISSN 0027-8424

Tian, C. X., Ohlund, D., Clauser, K., Carr, S. A., Tuveson, D. A., Hynes, R. O. (August 2015) Profiling of extracellular matrix proteins in pancreatic ductal adenocarcinoma progression and metastasis. Cancer Research, 75 (Supple). ISSN 0008-5472

Tian, C. X., Olund, D., Tuveson, D., Hynes, R. O. (July 2015) Understanding the roles of extracellular matrix proteins in pancreatic ductal adenocarcinoma progression and metastasis. Cancer Research, 75 (Supple). A45. ISSN 0008-5472

Tian, C., Ohlund, D., Rickelt, S., Lidstrom, T., Huang, Y., Hao, L., Zhao, R. T., Franklin, O., Bhatia, S. N., Tuveson, D. A., Hynes, R. O. (February 2020) Cancer-cell-derived matrisome proteins promote metastasis in pancreatic ductal adenocarcinoma. Cancer Res, 80 (7). pp. 1461-1474. ISSN 0008-5472

Tiriac, H., Belleau, P., Engle, D. D., Plenker, D., Deschenes, A., Somerville, T., Froeling, F. E. M., Burkhart, R. A., Denroche, R. E., Jang, G. H., Miyabayashi, K., Young, C. M., Patel, H., Ma, M., LaComb, J. F., Palmaira, R. L. D., Javed, A. A., Huynh, J. A., Johnson, M., Arora, K., Robine, N., Shah, M., Sanghvi, R., Goetz, A. B., Lowder, C. Y., Martello, L., Driehuis, E., Lecomte, N., Askan, G., Iacobuzio-Donahue, C. A., Clevers, H., Wood, L. D., Hruban, R. H., Thompson, E. D., Aguirre, A. J., Wolpin, B. M., Sasson, A., Kim, J., Wu, M., Bucobo, J. C., Allen, P. J., Sejpal, D. V., Nealon, W., Sullivan, J. D., Winter, J. M., Gimotty, P. A., Grem, J. L., DiMaio, D. J., Buscaglia, J. M., Grandgenett, P. M., Brody, J. R., Hollingsworth, M. A., O'Kane, G. M., Notta, F., Kim, E. J., Crawford, J. M., Devoe, C. E., Ocean, A., Wolfgang, C. L., Yu, K. H., Li, E., Vakoc, C. R., Hubert, B., Fischer, S. E., Wilson, J. M., Moffitt, R. A., Knox, J. J., Krasnitz, A., Gallinger, S., Tuveson, D. A. (May 2018) Organoid profiling identifies common responders to chemotherapy in pancreatic cancer. Cancer Discovery, 8 (9). pp. 1112-1129. ISSN 21598274 (Public Dataset)

Tiriac, H., Bucobo, J. C., Tzimas, D., Grewel, S., Lacomb, J. F., Rowehl, L. M., Nagula, S., Wu, M., Kim, J., Sasson, A., Vignesh, S., Martello, L., Munoz-Sagastibelza, M., Somma, J., Tuveson, D. A., Li, E., Buscaglia, J. M. (June 2018) Successful creation of pancreatic cancer organoids by means of EUS-guided fine-needle biopsy sampling for personalized cancer treatment. Gastrointest Endosc, 87 (6). pp. 1474-1480. ISSN 0016-5107

Tiriac, H., Burkhart, R. A., Belleau, P., Young, M. C., Ma, M., Engle, D. D., Li, E., Yu, K. H., Tuveson, D. A. (May 2018) Pharmacotyping patients using pancreatic cancer organoids. Cancer Research, 78 (10, Su). ISSN 0008-5472

Tiriac, H., Plenker, D., Baker, L. A., Tuveson, D. A. (March 2019) Organoid models for translational pancreatic cancer research. Curr Opin Genet Dev, 54. pp. 7-11. ISSN 0959-437x

Tournier, Cathy, Davies, Clare C., Harvey, Emma, McMahon, Raymond F. T., Finegan, Katherine G., Connor, Frances, Davis, Roger J., Tuveson, David A. (June 2015) Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Pancreatology, 15 (3, Sup). S36. ISSN 1424-3903

Tuveson, D. (December 2014) Progress in pancreatic cancer modeling. Molecular Cancer Research, 12 (Supple). ISSN 1541-7786

Tuveson, D., Engle, D., Hwang, C., Vakoc, C., Roe, J. S. (May 2018) GEMMs and GEOs to characterize pancreatic cancer initiation and progression. Cancer Research. ISSN 0008-5472

Tuveson, D. A. (November 2016) Detecting and killing pancreatic cancer. Human Gene Therapy, 27 (11). A12-A12. ISSN 1043-0342

Tuveson, D. A. (November 2014) Modeling pancreatic cancer biology and medicine. Molecular Cancer Research, 12 (Supple). ISSN 1541-7786

Tuveson, D. A. (November 2012) Talk from David Tuveson at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Tuveson, David A, Neoptolemos, John P (January 2012) Understanding Metastasis in Pancreatic Cancer: A Call for New Clinical Approaches. Cell, 148 (1–2). pp. 21-23. ISSN 0092-8674

Tuveson, David (September 2020) Overcoming the seven deadly hallmarks of pancreatic cancer. In: Special Conference on Pancreatic Cancer of American-Association-for-Cancer-Research (AACR).

V

Vakoc, C. R., Tuveson, D. A. (October 2017) Soils and Seeds That Initiate Pancreatic Cancer Metastasis. Cancer Discov, 7 (10). pp. 1067-1068. ISSN 2159-8274

Vakoc, C. R., Tuveson, D. A. (February 2017) Untangling the genetics from the epigenetics in pancreatic cancer metastasis. Nat Genet, 49 (3). pp. 323-324. ISSN 1061-4036

W

Wang, Zhikai, Yan, Ran, Li, Jiayun, Gao, Ya, Moresco, Philip, Yao, Min, Hechtman, Jaclyn F, Weiss, Matthew J, Janowitz, Tobias, Fearon, Douglas T (September 2020) Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy. BioRxiv. (Unpublished)

Weissmueller, S., Manchado, E., Saborowski, M., Morris, J. P. th, Wagenblast, E., Davis, C. A., Moon, S. H., Pfister, N. T., Tschaharganeh, D. F., Kitzing, T., Aust, D., Markert, E. K., Wu, J., Grimmond, S. M., Pilarsky, C., Prives, C., Biankin, A. V., Lowe, S. W. (April 2014) Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor beta Signaling. Cell, 157 (2). pp. 382-94. ISSN 1097-4172 (Electronic)0092-8674 (Linking)

Wolff, R. A., Wang-Gillam, A., Alvarez, H., Tiriac, H., Engle, D., Hou, S., Groff, A. F., Lucas, A. S., Bernard, V., Allenson, K., Castillo, J., Kim, D., Mulu, F., Huang, J., Stephens, B., Wistuba, I. I., Katz, M., Varadhachary, G., Park, Y., Hicks, J., Chinnaiyan, A., Scampavia, L., Spicer, T., Gerhardinger, C., Maitra, A., Tuveson, D., Rinn, J., Lizee, G., Yee, C., Levine, A. J. (March 2018) Dynamic changes during the treatment of pancreatic cancer. Oncotarget, 9 (19). pp. 14764-14790. ISSN 1949-2553

Y

Yan, Ran, Wang, Zhikai, Gao, Ya, Janowitz, Tobias, Fearon, Douglas T (May 2020) Immunogenicity and the CXCL12-coat control T cell accumulation in murine pancreatic cancer. In: UNSPECIFIED. (Unpublished)

Ying, H. Q., Elpek, K. G., Vinjamoori, A., Zimmerman, S. M., Chu, G. C., Yan, H. Y., Fletcher-Sananikone, E., Zhang, H. L., Liu, Y. C., Wang, W., Ren, X. J., Zheng, H. W., Kimmelman, A. C., Paik, J. H., Lim, C., Perry, S. R., Jiang, S., Malinn, B., Protopopov, A., Colla, S., Xiao, Y. H., Hezel, A. F., Bardeesy, N., Turley, S. J., Wang, Y. A. A., Chin, L., Thayer, S. P., DePinho, R. A. (July 2011) PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-kappa B-Cytokine Network. Cancer Discovery, 1 (2). pp. 158-169. ISSN 2159-8274

Ying, H. Q., Kimmelman, A. C., Lyssiotis, C. A., Hua, S. J., Chu, G. C., Fletcher-Sananikone, E., Locasale, J. W., Son, J., Zhang, H. L., Coloff, J. L., Yan, H. Y., Wang, W., Chen, S. J., Viale, A., Zheng, H. W., Paik, J. H., Lim, C., Guimaraes, A. R., Martin, E. S., Chang, J., Hezel, A. F., Perry, S. R., Hu, J., Gan, B. Y., Xiao, Y. H., Asara, J. M., Weissleder, R., Wang, Y. A., Chin, L., Cantley, L. C., DePinho, R. A. (April 2012) Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism. Cell, 149 (3). pp. 656-670. ISSN 0092-8674

Z

Zambirinis, C. P., Levie, E., Nguy, S., Avanzi, A., Barilla, R., Xu, Y., Seifert, L., Daley, D., Greco, S. H., Deutsch, M., Jonnadula, S., Torres-Hernandez, A., Tippens, D., Pushalkar, S., Eisenthal, A., Saxena, D., Ahn, J., Hajdu, C., Engle, D. D., Tuveson, D., Miller, G. (October 2015) TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. J Exp Med. ISSN 1540-9538 (Electronic)0022-1007 (Linking)

Zhang, N., Lyons, S., Lim, E., Lassota, P. (August 2009) A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging. Clin Cancer Res, 15 (15). pp. 4915-24. ISSN 1078-0432 (Print)1078-0432 (Linking)

Ö

Öhlund, Daniel, Handly-Santana, Abram, Elyada, Ela, Biffi, Giulia, Tuveson, David A. (June 2016) Pancreatic stellate cell heterogeneity in cancer. Pancreatology, 16 (3, Sup). S15. ISSN 1424-3903

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