Items where Subject is "diseases & disorders > cancer > cancer types > pancreatic cancer"

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Number of items at this level: 72.

B

Baker, Lindsey A., Tiriac, Hervé, Clevers, Hans, Tuveson, David A. (2016) Modeling Pancreatic Cancer with Organoids. Trends in Cancer, 2 (4). pp. 176-190. ISSN 2405-8033

Bapiro, T. E., Frese, K. K., Courtin, A., Bramhall, J. L., Madhu, B., Cook, N., Neesse, A., Griffiths, J. R., Tuveson, D. A., Jodrell, D. I., Richards, F. M. (2014) Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo. British Journal of Cancer, 111 (2). pp. 318-325. ISSN 0007-0920

Baumgart, S., Chen, N. M., Siveke, J. T., Konig, A., Zhang, J. S., Singh, S. K., Wolf, E., Bartkuhn, M., Esposito, I., Hessmann, E., Reinecke, J., Nikorowitsch, J., Brunner, M., Singh, G., Fernandez-Zapico, M. E., Smyrk, T., Bamlet, W. R., Eilers, M., Neesse, A., Gress, T. M., Billadeau, D. D., Tuveson, D., Urrutia, R., Ellenrieder, V. (2014) Inflammation-Induced NFATc1-STAT3 Transcription Complex Promotes Pancreatic Cancer Initiation by Kras(G12D). Cancer Discovery, 4 (6). pp. 688-701. ISSN 2159-8274

Biffi, G., Ohlund, D., Tuveson, D. (2016) Building up the tension between the epithelial and stromal compartment in pancreatic ductal adenocarcinoma. Cell Death Differ, 23 (8). pp. 1265-1266. ISSN 1476-5403 (Electronic)1350-9047 (Linking)

Biffi, G., Tuveson, D. A. (2017) Cancer: Double trouble for tumours. Nature, 542 (7639). pp. 34-35. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Boj, S. F., Hwang, C. I., Baker, L. A., Engle, D. D., Tuveson, D. A., Clevers, H. (2016) Model organoids provide new research opportunities for ductal pancreatic cancer. Mol Cell Oncol, 3 (1). e1014757. ISSN 2372-3556 (Electronic)2372-3556 (Linking)

Boj, Sylvia F, Hwang, Chang-Il, Baker, Lindsey A, Chio, Iok In Christine, Engle, Dannielle D, Corbo, Vincenzo, Jager, Myrthe, Ponz-Sarvise, Mariano, Tiriac, Hervé, Spector, Mona S, Gracanin, Ana, Oni, Tobiloba, Yu, Kenneth H, van Boxtel, Ruben, Huch, Meritxell, Rivera, Keith D, Wilson, John P, Feigin, Michael E, Öhlund, Daniel, Handly-Santana, Abram, Ardito-Abraham, Christine M, Ludwig, Michael, Elyada, Ela, Alagesan, Brinda, Biffi, Giulia, Yordanov, Georgi N, Delcuze, Bethany, Creighton, Brianna, Wright, Kevin, Park, Youngkyu, Morsink, Folkert H M., Molenaar, I.  Quintus, Borel Rinkes, Inne H, Cuppen, Edwin, Hao, Yuan, Jin, Ying, Nijman, Isaac J, Iacobuzio-Donahue, Christine, Leach, Steven D, Pappin, Darryl J, Hammell, Molly, Klimstra, David S, Basturk, Olca, Hruban, Ralph H, Offerhaus, George Johan, Vries, Robert G J., Clevers, Hans, Tuveson, David A (2015) Organoid Models of Human and Mouse Ductal Pancreatic Cancer. Cell, 160 (1-2). pp. 324-338. ISSN 0092-8674

C

Carapua, E. F., Gemenetzidis, E., Feig, C., Tuveson, D., Kocher, H. (2015) Developing drug combinations to co-target pancreatic cancer and its supporting stroma. Cancer Research, 75 (Supple). B72. ISSN 0008-5472

Chen, S., Auletta, T., Dovirak, O., Hutter, C., Kuntz, K., El-Ftesi, S., Kendall, J., Han, H., Von Hoff, D. D., Ashfaq, R., Maitra, A., Iacobuzio-Donahue, C. A., Hruban, R. H., Lucito, R. (2008) Copy number alterations in pancreatic cancer identify recurrent PAK4 amplification. Cancer Biol Ther, 7 (11). pp. 1793-1802.

Chio, I. I. C., Jafarnejad, S. M., Ponz-Sarvise, M., Park, Y., Rivera, K., Palm, W., Ohlund, D., Hammell, M., Crawford, H., Schmidt, E., Thompson, C., Pappin, D., Sonenberg, N., Tuveson, D. (2017) NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer. Cancer Research, 77 (Supple). ISSN 0008-54721538-7445

Chio, II, Tuveson, D. A. (2017) ROS in translation: Chink in the armor. Cell Cycle, 16 (4). pp. 297-298. ISSN 1551-4005

Chio, Iok In Christine, Jafarnejad, Seyed Mehdi, Ponz-Sarvise, Mariano, Park, Youngkyu, Rivera, Keith, Palm, Wilhelm, Wilson, John, Sangar, Vineet, Hao, Yuan, Öhlund, Daniel, Wright, Kevin, Filippini, Dea, Lee, Eun Jung, Da Silva, Brandon, Schoepfer, Christina, Wilkinson, John Erby, Buscaglia, Jonathan M, DeNicola, Gina M, Tiriac, Herve, Hammell, Molly, Crawford, Howard C, Schmidt, Edward E, Thompson, Craig B, Pappin, Darryl J, Sonenberg, Nahum, Tuveson, David A (2016) NRF2 Promotes Tumor Maintenance by Modulating mRNA Translation in Pancreatic Cancer. Cell, 166 (4). pp. 963-976. ISSN 0092-8674

Cook, N., Frese, K. K., Bapiro, T. E., Jacobetz, M. A., Gopinathan, A., Miller, J. L., Rao, S. S., Demuth, T., Howat, W. J., Jodrell, D. I., Tuveson, D. A. (2012) Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma. J Exp Med, 209 (3). pp. 437-44. ISSN 1540-9538 (Electronic)0022-1007 (Linking)

D

Davies, C. C., Harvey, E., McMahon, R. F. T., Finegan, K. G., Connor, F., Davis, R. J., Tuveson, D. A., Tournier, C. (2014) Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Cancer Research, 74 (12). pp. 3344-3356. ISSN 15387445

E

Eberl, M., Klingler, S., Mangelberger, D., Loipetzberger, A., Damhofer, H., Zoidl, K., Schnidar, H., Hache, H., Bauer, H. C., Solca, F., Hauser-Kronberger, C., Ermilov, A. N., Verhaegen, M. E., Bichakjian, C. K., Dlugosz, A. A., Nietfeld, W., Sibilia, M., Lehrach, H., Wierling, C., Aberger, F. (2012) Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells. EMBO Molecular Medicine, 4 (3). pp. 218-233. ISSN 17574676 (ISSN)

F

Feig, C., Gopinathan, A., Neesse, A., Chan, D. S., Cook, N., Tuveson, D. A. (2012) The pancreas cancer microenvironment. Clin Cancer Res, 18 (16). pp. 4266-76. ISSN 1078-0432 (Print)1078-0432 (Linking)

Feig, C., Jones, J. O., Kraman, M., Wells, R. J. B., Deonarine, A., Chan, D. S., Connell, C. M., Roberts, E. W., Zhao, Q., Caballero, O. L., Teichmann, S. A., Janowitz, T., Jodrell, D. I., Tuveson, D. A., Fearon, D. T. (2013) Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 110 (50). pp. 20212-20217. ISSN 00278424 (ISSN)

Feigin, M. E., Tuveson, D. A. (2017) Challenges and Opportunities in Modeling Pancreatic Cancer. Cold Spring Harb Symp Quant Biol. ISSN 0091-7451

Frese, K. K., Neesse, A., Cook, N., Bapiro, T. E., Lolkema, M. P., Jodrell, D. I., Tuveson, D. A. (2012) nab-Paclitaxel potentiates gemcitabine activity by reducing cytidine deaminase levels in a mouse model of pancreatic cancer. Cancer Discov, 2 (3). pp. 260-9. ISSN 2159-8290 (Electronic)2159-8274 (Linking)

H

Hwang, C. I., Boj, S. F., Clevers, H., Tuveson, D. A. (2016) Pre-clinical Models of Pancreatic Ductal Adenocarcinoma. J Pathol, 238 (2). pp. 197-204. ISSN 1096-9896 (Electronic)0022-3417 (Linking)

I

Ireland, L., Santos, A., Ahmed, M. S., Rainer, C., Nielsen, S. R., Quaranta, V., Weyer-Czernilofsky, U., Engle, D. D., Perez-Mancera, P., Coupland, S. E., Taktak, A. F., Bogenrieder, T., Tuveson, D. A., Campbell, F., Schmid, M. C., Mielgo, A. (2016) Chemoresistance in pancreatic cancer is driven by stroma-derived insulin-like growth factors. Cancer Res, 76 (23). pp. 6851-6863. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

J

Jacobetz, M. A., Chan, D. S., Neesse, A., Bapiro, T. E., Cook, N., Frese, K. K., Feig, C., Nakagawa, T., Caldwell, M. E., Zecchini, H. I., Lolkema, M. P., Jiang, P., Kultti, A., Thompson, C. B., Maneval, D. C., Jodrell, D. I., Frost, G. I., Shepard, H. M., Skepper, J. N., Tuveson, D. A. (2013) Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut, 62 (1). pp. 112-20. ISSN 1468-3288 (Electronic)0017-5749 (Linking)

Jenkinson, C., Elliott, V., Evans, A., Oldfield, L., Jenkins, R. E., O'Brien, D. P., Apostolidou, S., Gentry-Maharaj, A., Fourkala, E. O., Jacobs, I., Menon, U., Cox, T. F., Campbell, F., Pereira, S. P., Tuveson, D. A., Park, P. K., Greenhalf, W., Sutton, R. Professor, Timms, J. F., Neoptolemos, J., Costello, E. (2016) Decreased serum thrombospondin-1 levels in pancreatic cancer patients up to 24 months prior to clinical diagnosis: association with diabetes mellitus. Clin Cancer Res, 22 (7). pp. 1734-43. ISSN 1078-0432 (Electronic)1078-0432 (Linking)

Jenkinson, C., Elliott, V. L., Evans, A., Oldfield, L., Timms, J. F., Gentry-Maharaj, A., Menon, U., Cox, T., Campbell, F., Sutton, R., Pereira, S. P., Tuveson, D. A., Greenhalf, W., Neoptolemos, J. P., Costello, E. (2015) Decreased Serum Thrombospondin-1 Levels in Pancreatic Ductal Adenocarcinoma Patients: An Early Indicator of Cancer or Diabetes Development? Pancreas, 44 (8). p. 1383. ISSN 0885-3177

Jenkinson, Claire, Elliott, Victoria, Evans, Anthony, Oldfield, Lucy, O'Brien, Darragh, Apostolidou, Sophia, Gentry-Maharaj, Aleksandra, Fourkala, Evangelia- O., Jacobs, Ian, Menon, Usha, Cox, Trevor, Campbell, Fiona, Tuveson, David, Greenhalf, William, Sutton, Robert, Pereira, Stephen, Timms, John, Neoptolemos, John, Costello, Eithne (2015) Decreased serum thrombospondin-1 levels in pancreatic ductal adenocarcinoma patients: an early indicator of disease or diabetes mellitus development? Pancreatology, 15 (3, Sup). S28. ISSN 1424-3903

K

Kimmelman, A. C., Hezel, A. F., Aguirre, A. J., Zheng, H. W., Paik, J. H., Ying, H. Q., Chu, G. C., Zhang, J. X., Sahin, E., Yeo, G. M., Ponugoti, A., Nabioullin, R., Deroo, S., Yang, S. D., Wang, X. X., McGrath, J. P., Protopopova, M., Ivanova, E., Zhang, J. H., Feng, B., Tsao, M. S., Redston, M., Protopopov, A., Xiao, Y. H., Futreal, P. A., Hahn, W. C., Klimstra, D. S., Chin, L., DePinho, R. A. (2008) Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America, 105 (49). pp. 19372-19377. ISSN 0027-8424

Kleeff, J., Korc, M., Apte, M., La Vecchia, C., Johnson, C. D., Biankin, A. V., Neale, R. E., Tempero, M., Tuveson, D. A., Hruban, R. H., Neoptolemos, J. P. (2016) Pancreatic cancer. Nat Rev Dis Primers, 2. p. 16022. ISSN 2056-676X (Electronic)2056-676X (Linking)

Kultti, A., Zhao, C. M., Singha, N. C., Zimmerman, S., Osgood, R. J., Symons, R., Jiang, P., Li, X. M., Thompson, C. B., Infante, J. R., Jacobetz, M. A., Tuveson, D. A., Frost, G. I., Shepard, H. M., Huang, Z. D. (2014) Accumulation of Extracellular Hyaluronan by Hyaluronan Synthase 3 Promotes Tumor Growth and Modulates the Pancreatic Cancer Microenvironment. Biomed Research International. p. 15. ISSN 2314-6133

Kultti, A., Zhao, C. M., Zimmerman, S., Osgood, R. J., Chen, Y. L., Symons, R., Jiang, P., Thompson, C. B., Tuveson, D. A., Frost, G. I., Shepard, H. M., Huang, Z. D. (2014) Extracellular hyaluronan accumulation by hyaluronan synthase 3 promotes pancreatic cancer growth and modulates tumor microenvironment via epithelial-mesenchymal transition. Cancer Research, 74 (19). ISSN 0008-5472

L

Lucito, R., Suresh, S., Walter, K., Pandey, A., Lakshmi, B., Krasnitz, A., Sebat, J., Wigler, M. H., Klein, A. P., Brune, K., Palmisano, E., Maitra, A., Goggins, M., Hruban, R. H. (2007) Copy-Number Variants in Patients with a Strong Family History of Pancreatic Cancer. Cancer Biol Ther, 6 (10). pp. 1592-9. ISSN 1538-4047 (Print)

Ludwig, M. R., Kojima, K., Bowersock, G. J., Chen, D., Jhala, N. C., Buchsbaum, D. J., Grizzle, W. E., Klug, C. A., Mobley, J. A. (2016) Surveying the serologic proteome in a tissue specific kras(G12D) knockin mouse model of pancreatic cancer. Proteomics, 16 (3). pp. 516-31. ISSN 1615-9861 (Electronic)1615-9853 (Linking)

M

Mahajan, Ujwal Mukund, Teller, Steffen, Sendler, Matthias, Schwaiger, Theresa, Glöckl, Gunner, Aurich, Konstanze, Partecke, Lars Ivo, Hadlich, Steffen, Weiss, Frank Ulrich, Kühn, Jens P., Tuveson, David, Lerch, Markus M., Mayerle, Julia (2013) In vivo imaging and targeted siRNA delivery using superparamagnetic nanoparticles in pancreatic ductal adenocarcinoma. Pancreatology, 13 (3, Sup). S19. ISSN 1424-3903

Maki, R. G., Livingston, P. O., Lewis, J. J., Janetzki, S., Klimstra, D., Desantis, D., Srivastava, P. K., Brennan, M. F. (2007) A phase I pilot study of autologous heat shock protein vaccine HSPPC-96 in patients with resected pancreatic adenocarcinoma. Dig Dis Sci, 52 (8). pp. 1964-72. ISSN 0163-2116 (Print)0163-2116 (Linking)

N

Neesse, A., Algul, H., Tuveson, D. A., Gress, T. M. (2015) Stromal biology and therapy in pancreatic cancer: a changing paradigm. Gut, 64 (9). pp. 1476-1484. ISSN 1468-3288 (Electronic)0017-5749 (Linking)

Neesse, A., Frese, K. K., Bapiro, T. E., Nakagawa, T., Sternlicht, M. D., Seeley, T. W., Pilarsky, C., Jodrell, D. I., Spong, S. M., Tuveson, D. A. (2013) CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America, 110 (30). pp. 12325-30. ISSN 0027-8424

Neesse, A., Frese, K. K., Chan, D. S., Bapiro, T. E., Howat, W. J., Richards, F. M., Ellenrieder, V., Jodrell, D. I., Tuveson, D. A. (2013) SPARC independent drug delivery and antitumour effects of nab-paclitaxel in genetically engineered mice. Gut, 63 (6). pp. 974-983. ISSN 00175749 (ISSN)

Neesse, A., Krug, S., Gress, T. M., Tuveson, D. A., Michl, P. (2013) Emerging concepts in pancreatic cancer medicine: targeting the tumor stroma. Onco Targets Ther, 7. pp. 33-43. ISSN 1178-6930 (Print)1178-6930

Neesse, A., Michl, P., Tuveson, D. A., Ellenrieder, V. (2014) nab-Paclitaxel: Novel Clinical and Experimental Evidence in Pancreatic Cancer. Zeitschrift fur Gastroenterologie, 52 (4). pp. 360-366. ISSN 0044-2771

Nielsen, S. R., Quaranta, V., Linford, A., Emeagi, P., Rainer, C., Santos, A., Ireland, L., Sakai, T., Sakai, K., Kim, Y. S., Engle, D., Campbell, F., Palmer, D., Ko, J. H., Tuveson, D. A., Hirsch, E., Mielgo, A., Schmid, M. C. (2016) Macrophage-secreted granulin supports pancreatic cancer metastasis by inducing liver fibrosis. Nat Cell Biol, 18 (5). pp. 549-60. ISSN 1476-4679 (Electronic)1465-7392 (Linking)

O

Ohlund, D., Handly-Santana, A., Biffi, G., Elyada, E., Almeida, A. S., Ponz-Sarvise, M., Corbo, V., Oni, T. E., Hearn, S. A., Lee, E. J., Chio, II, Hwang, C. I., Tiriac, H., Baker, L. A., Engle, D. D., Feig, C., Kultti, A., Egeblad, M., Fearon, D. T., Crawford, J. M., Clevers, H., Park, Y., Tuveson, D. A. (2017) Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med, 214 (3). pp. 579-596. ISSN 0022-1007

Ohman, K. A., Hashim, Y. M., Vangveravong, S., Nywening, T. M., Cullinan, D. R., Goedegebuure, S. P., Liu, J., Van Tine, B. A., Tiriac, H., Tuveson, D. A., DeNardo, D. G., Spitzer, D., Mach, R. H., Hawkins, W. G. (2016) Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic. Oncotarget. ISSN 1949-2553 (Electronic)1949-2553 (Linking)

P

Perez-Mancera, P. A., Rust, A. G., van der Weyden, L., Kristiansen, G., Li, A., Sarver, A. L., Silverstein, K. A., Grutzmann, R., Aust, D., Rummele, P., Knosel, T., Herd, C., Stemple, D. L., Kettleborough, R., Brosnan, J. A., Li, A., Morgan, R., Knight, S., Yu, J., Stegeman, S., Collier, L. S., ten Hoeve, J. J., de Ridder, J., Klein, A. P., Goggins, M., Hruban, R. H., Chang, D. K., Biankin, A. V., Grimmond, S. M., Wessels, L. F., Wood, S. A., Iacobuzio-Donahue, C. A., Pilarsky, C., Largaespada, D. A., Adams, D. J., Tuveson, D. A. (2012) The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature, 486 (7402). pp. 266-70. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Peverley, L. V., Halbrook, C. J., Hall, J. C., Ardito, C. M., Crawford, H. C. (2015) Investigating the role of ADAM10 in pancreatic tumor differentiation. Cancer Research, 75 (Supple). A77. ISSN 0008-5472

Ponz-Sarvise, M., Corbo, V., Ohlund, D., Oni, T., Handly-Santana, A., Engle, D., Tiriac, H., Chio, C., Feigin, M., Baker, L., Ardito-Abraham, C., Park, Y., Hwang, C., Elyada, E., Yu, K., Clevers, H., Tuveson, D. A. (2014) Pancreatic ductal organoids as a new platform for drug discovery. European Journal of Cancer, 50. p. 63. ISSN 0959-8049

Ponz-Sarvise, Mariano, Tuveson, David A., Yu, Kenneth H. (2015) Mouse Models of Pancreatic Ductal Adenocarcinoma. Hematology/Oncology Clinics of North America, 29 (4). pp. 609-617. ISSN 0889-8588

R

Rindi, G., Efrat, S., Ghatei, M. A., Bloom, S. R., Solcia, E., Hanahan, D., Polak, J. M. (1990) Expression of General Neuroendocrine Markers and Hormones in Pancreatic Glucagonomas of Transgenic Mice. Journal of Pathology, 160 (2). A154-A154. ISSN 0022-3417

Rindi, G., Efrat, S., Ghatei, M. A., Bloom, S. R., Solcia, E., Polak, J. M. (1991) Glucagonomas of transgenic mice express a wide range of general neuroendocrine markers and bioactive peptides. Virchows Arch A Pathol Anat Histopathol, 419 (2). pp. 115-29. ISSN 0174-7398 (Print)0174-7398 (Linking)

Roberts, N. J., Norris, A. L., Petersen, G. M., Bondy, M. L., Brand, R., Gallinger, S., Kurtz, R. C., Olson, S. H., Rustgi, A. K., Schwartz, A. G., Stoffel, E. M., Syngal, S., Zogopoulos, G., Ali, S. Z., Axilbund, J., Chaffee, K. G., Chen, Y. C., Cote, M. L., Childs, E. J., Douville, C., Goes, F. S., Herman, J. M., Iacobuzio-Donahue, C., Kramer, M., Makohon-Moore, A., McCombie, R. W., McMahon, K. W., Niknafs, N., Parla, J., Pirooznia, M., Potash, J. B., Rhim, A. D., Smith, A. L., Wang, Y., Wolfgang, C. L., Wood, L. D., Zandi, P. P., Goggins, M., Karchin, R., Eshleman, J. R., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Hruban, R. H., Klein, A. P. (2016) Whole genome sequencing defines the genetic heterogeneity of familial pancreatic cancer. Cancer Discov, 6 (2). pp. 166-175. ISSN 2159-8290 (Electronic)2159-8274 (Linking)

Rosati, A., Basile, A., D'Auria, R., d'Avenia, M., De Marco, M., Falco, A., Festa, M., Guerriero, L., Iorio, V., Parente, R., Pascale, M., Marzullo, L., Franco, R., Arra, C., Barbieri, A., Rea, D., Menichini, G., Hahne, M., Bijlsma, M., Barcaroli, D., Sala, G., di Mola, F. F., di Sebastiano, P., Todoric, J., Antonucci, L., Corvest, V., Jawhari, A., Firpo, M. A., Tuveson, D. A., Capunzo, M., Karin, M., De Laurenzi, V., Turco, M. C. (2015) BAG3 promotes pancreatic ductal adenocarcinoma growth by activating stromal macrophages. Nat Commun, 6. p. 8695. ISSN 2041-1723 (Electronic)2041-1723 (Linking)

Rosati, A., Basile, A., D'Auria, R., d'Avenia, M., De Marco, M., Falco, A., Festa, M., Guerriero, L., Iorio, V., Pascale, M., Franco, R., Arra, C., Barbieri, A., Rea, D., Menichini, G., Hahne, M., Bijlsma, M., Barcaroli, D., Tuveson, D. A., Todoric, J., Karin, M., De Laurenzi, V., Turco, M. C. (2015) PDAC cells release BAG3 that activates a paracrine loop with stromal macrophages. Cancer Research, 75 (Supple). Abstract 2393. ISSN 0008-5472

Roy, I., McAllister, D., Gorse, E., Dixon, K., Cheng, G., Getschman, A., Engle, D., Tsai, S., Tuveson, D., Evans, D., Volkman, B., Kalyanaraman, B., Dwinell, M. (2015) Chemokine biased agonists regulate pancreatic cancer migration and metastasis through bioenergetic signaling. Cancer Research, 75 (Supple). B55. ISSN 0008-5472

Roy, I., McAllister, D. M., Gorse, E., Dixon, K., Piper, C. T., Zimmerman, N. P., Getschman, A. E., Tsai, S., Engle, D. D., Evans, D. B., Volkman, B. F., Kalyanaraman, B., Dwinell, M. B. (2015) Pancreatic Cancer Cell Migration and Metastasis Is Regulated by Chemokine-Biased Agonism and Bioenergetic Signaling. Cancer Res, 75 (17). pp. 3529-42. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

S

Saiyin, H., Ardito-Abraham, C. M., Wu, Y., Wei, Y., Fang, Y., Han, X., Li, J., Zhou, P., Yi, Q., Maitra, A., Liu, J. O., Tuveson, D. A., Lou, W., Yu, L. (2015) Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma. J Pathol, 236 (2). pp. 142-154. ISSN 0022-3417

Schlomann, U., Koller, G., Conrad, C., Ferdous, T., Golfi, P., Garcia, A. M., Hofling, S., Parsons, M., Costa, P., Soper, R., Bossard, M., Hagemann, T., Roshani, R., Sewald, N., Ketchem, R. R., Moss, M. L., Rasmussen, F. H., Miller, M. A., Lauffenburger, D. A., Tuveson, D. A., Nimsky, C., Bartsch, J. W. (2015) ADAM8 as a drug target in pancreatic cancer. Nature Communications, 6. p. 6175. ISSN 2041-1723

Seifert, L., Werba, G., Tiwari, S., Giao Ly, N. N., Alothman, S., Alqunaibit, D., Avanzi, A., Barilla, R., Daley, D., Greco, S. H., Torres-Hernandez, A., Pergamo, M., Ochi, A., Zambirinis, C. P., Pansari, M., Rendon, M., Tippens, D., Hundeyin, M., Mani, V. R., Hajdu, C., Engle, D., Miller, G. (2016) The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression. Nature, 532 (7598). pp. 245-9. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Serrao, E. M., Kettunen, M. I., Rodrigues, T. B., Dzien, P., Wright, A. J., Gopinathan, A., Gallagher, F. A., Lewis, D. Y., Frese, K. K., Almeida, J., Howat, W. J., Tuveson, D. A., Brindle, K. M. (2016) MRI with hyperpolarised [1-13C]pyruvate detects advanced pancreatic preneoplasia prior to invasive disease in a mouse model. Gut, 65 (3). pp. 465-75. ISSN 1468-3288 (Electronic)0017-5749 (Linking)

Sherman, Mara H, Yu, Ruth T, Engle, Dannielle D, Ding, Ning, Atkins, Annette R, Tiriac, Herve, Collisson, Eric A, Connor, Frances, Van Dyke, Terry, Kozlov, Serguei, Martin, Philip, Tseng, Tiffany W, Dawson, David W, Donahue, Timothy R, Masamune, Atsushi, Shimosegawa, Tooru, Apte, Minoti V, Wilson, Jeremy S, Ng, Beverly, Lau, Sue Lynn, Gunton, Jenny E, Wahl, Geoffrey M, Hunter, Tony, Drebin, Jeffrey A, O’Dwyer, Peter J, Liddle, Christopher, Tuveson, David A, Downes, Michael, Evans, Ronald M (2014) Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy. Cell, 159 (1). pp. 80-93. ISSN 0092-8674

Shields, M. A., Maguin, P., Kumar, P., Dallas, S. L., Egeblad, M. (2015) Lysyl oxidases are poor therapeutic targets in pancreatic cancer. Cancer Research, 75 (Supple). A43. ISSN 0008-5472

T

Tian, C. X., Ohlund, D., Clauser, K., Carr, S. A., Tuveson, D. A., Hynes, R. O. (2015) Profiling of extracellular matrix proteins in pancreatic ductal adenocarcinoma progression and metastasis. Cancer Research, 75 (Supple). ISSN 0008-5472

Tian, C. X., Olund, D., Tuveson, D., Hynes, R. O. (2015) Understanding the roles of extracellular matrix proteins in pancreatic ductal adenocarcinoma progression and metastasis. Cancer Research, 75 (Supple). A45. ISSN 0008-5472

Tournier, Cathy, Davies, Clare C., Harvey, Emma, McMahon, Raymond F. T., Finegan, Katherine G., Connor, Frances, Davis, Roger J., Tuveson, David A. (2015) Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Pancreatology, 15 (3, Sup). S36. ISSN 1424-3903

Tuveson, D. (2014) Progress in pancreatic cancer modeling. Molecular Cancer Research, 12. ISSN 1541-7786

Tuveson, D. A. (2016) Detecting and killing pancreatic cancer. Human Gene Therapy, 27 (11). A12-A12. ISSN 1043-0342

Tuveson, D. A. (2014) Modeling pancreatic cancer biology and medicine. Molecular Cancer Research, 12 (Supple). ISSN 1541-7786

Tuveson, D. A. (2012) Talk from David Tuveson at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Tuveson, David A, Neoptolemos, John P (2012) Understanding Metastasis in Pancreatic Cancer: A Call for New Clinical Approaches. Cell, 148 (1–2). pp. 21-23. ISSN 0092-8674

V

Vakoc, C. R., Tuveson, D. A. (2017) Untangling the genetics from the epigenetics in pancreatic cancer metastasis. Nat Genet, 49 (3). pp. 323-324. ISSN 1061-4036

W

Weissmueller, S., Manchado, E., Saborowski, M., Morris, J. P. th, Wagenblast, E., Davis, C. A., Moon, S. H., Pfister, N. T., Tschaharganeh, D. F., Kitzing, T., Aust, D., Markert, E. K., Wu, J., Grimmond, S. M., Pilarsky, C., Prives, C., Biankin, A. V., Lowe, S. W. (2014) Mutant p53 Drives Pancreatic Cancer Metastasis through Cell-Autonomous PDGF Receptor beta Signaling. Cell, 157 (2). pp. 382-94. ISSN 1097-4172 (Electronic)0092-8674 (Linking)

Y

Ying, H. Q., Elpek, K. G., Vinjamoori, A., Zimmerman, S. M., Chu, G. C., Yan, H. Y., Fletcher-Sananikone, E., Zhang, H. L., Liu, Y. C., Wang, W., Ren, X. J., Zheng, H. W., Kimmelman, A. C., Paik, J. H., Lim, C., Perry, S. R., Jiang, S., Malinn, B., Protopopov, A., Colla, S., Xiao, Y. H., Hezel, A. F., Bardeesy, N., Turley, S. J., Wang, Y. A. A., Chin, L., Thayer, S. P., DePinho, R. A. (2011) PTEN Is a Major Tumor Suppressor in Pancreatic Ductal Adenocarcinoma and Regulates an NF-kappa B-Cytokine Network. Cancer Discovery, 1 (2). pp. 158-169. ISSN 2159-8274

Ying, H. Q., Kimmelman, A. C., Lyssiotis, C. A., Hua, S. J., Chu, G. C., Fletcher-Sananikone, E., Locasale, J. W., Son, J., Zhang, H. L., Coloff, J. L., Yan, H. Y., Wang, W., Chen, S. J., Viale, A., Zheng, H. W., Paik, J. H., Lim, C., Guimaraes, A. R., Martin, E. S., Chang, J., Hezel, A. F., Perry, S. R., Hu, J., Gan, B. Y., Xiao, Y. H., Asara, J. M., Weissleder, R., Wang, Y. A., Chin, L., Cantley, L. C., DePinho, R. A. (2012) Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism. Cell, 149 (3). pp. 656-670. ISSN 0092-8674

Z

Zambirinis, C. P., Levie, E., Nguy, S., Avanzi, A., Barilla, R., Xu, Y., Seifert, L., Daley, D., Greco, S. H., Deutsch, M., Jonnadula, S., Torres-Hernandez, A., Tippens, D., Pushalkar, S., Eisenthal, A., Saxena, D., Ahn, J., Hajdu, C., Engle, D. D., Tuveson, D., Miller, G. (2015) TLR9 ligation in pancreatic stellate cells promotes tumorigenesis. J Exp Med. ISSN 1540-9538 (Electronic)0022-1007 (Linking)

Ö

Öhlund, Daniel, Handly-Santana, Abram, Elyada, Ela, Biffi, Giulia, Tuveson, David A. (2016) Pancreatic stellate cell heterogeneity in cancer. Pancreatology, 16 (3, Sup). S15. ISSN 1424-3903

This list was generated on Sun Apr 30 10:44:18 2017 EDT.
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