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Paper

Ohlund, D., Handly-Santana, A., Biffi, G., Elyada, E., Almeida, A. S., Ponz-Sarvise, M., Corbo, V., Oni, T. E., Hearn, S. A., Lee, E. J., Chio, II, Hwang, C. I., Tiriac, H., Baker, L. A., Engle, D. D., Feig, C., Kultti, A., Egeblad, M., Fearon, D. T., Crawford, J. M., Clevers, H., Park, Y., Tuveson, D. A. (2017) Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med, 214 (3). pp. 579-596. ISSN 0022-1007

Perurena, N., Zandueta, C., Martinez-Canarias, S., Moreno, H., Vicent, S., Almeida, A. S., Guruceaga, E., Gomis, R. R., Santisteban, M., Egeblad, M., Hermida, J., Lecanda, F. (2017) EPCR promotes breast cancer progression by altering SPOCK1/testican 1-mediated 3D growth. J Hematol Oncol, 10 (1). p. 23. ISSN 1756-8722 (Electronic)1756-8722 (Linking)

Park, J., Wysocki, R. W., Amoozgar, Z., Maiorino, L., Fein, M. R., Jorns, J., Schott, A. F., Kinugasa-Katayama, Y., Lee, Y., Won, N. H., Nakasone, E. S., Hearn, S. A., Kuttner, V., Qiu, J., Almeida, A. S., Perurena, N., Kessenbrock, K., Goldberg, M. S., Egeblad, M. (2016) Cancer cells induce metastasis-supporting neutrophil extracellular DNA traps. Sci Transl Med, 8 (361). 361ra138. ISSN 1946-6242 (Electronic)1946-6234 (Linking)

Arun, G., Diermeier, S., Akerman, M., Chang, K. C., Wilkinson, J. E., Hearn, S., Kim, Y., MacLeod, A. R., Krainer, A. R., Norton, L., Brogi, E., Egeblad, M., Spector, D. L. (2016) Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss. Cancer Research, 76 (Supple). ISSN 0008-5472

Arun, G., Diermeier, S., Akerman, M., Chang, K. C., Wilkinson, J. E., Hearn, S., Kim, Y., MacLeod, A. R., Krainer, A. R., Norton, L., Brogi, E., Egeblad, M., Spector, D. L. (2016) Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes Dev, 30 (1). pp. 34-51. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Shields, M. A., Maguin, P., Kumar, P., Dallas, S. L., Egeblad, M. (2015) Lysyl oxidases are poor therapeutic targets in pancreatic cancer. Cancer Research, 75 (Supple). A43. ISSN 0008-5472

Park, Jae-Hyun, Rasch, Morten Grønbech, Qiu, Jing, Lund, Ida Katrine, Egeblad, Mikala (2015) Presence of Insulin-Like Growth Factor Binding Proteins Correlates With Tumor-Promoting Effects of Matrix Metalloproteinase 9 in Breast Cancer. Neoplasia, 17 (5). pp. 421-433. ISSN 1476-5586

Egeblad, M., Nakasone, E., Askautrud, H., Wysocki, R., Fein, M., Kees, T., Park, J., Park, J. H. (2014) Understanding drug responses and resistance mechanisms using imaging in live mice. Molecular Cancer Research, 12 (Supple). ISSN 1541-7786

Ewald, A. J., Egeblad, M. (2014) Cancer: Sugar-coated cell signalling. Nature, 511 (7509). pp. 298-9. ISSN 0028-0836

Rose, S., Egeblad, M. (2014) Q&A: Mikala Egeblad on Tumor Microenvironment. Cancer Discovery, 4 (5). p. 503. ISSN 2159-8274

Rajaram, M., Li, J., Egeblad, M., Powers, R. S. (2013) System-wide analysis reveals a complex network of tumor-fibroblast interactions involved in tumorigenicity. PLoS Genetics, 9 (9). e1003789. ISSN 1553-7404 (Electronic)1553-7390 (Linking)

Youmans, S. J., Fein, M. R., Wirkowski, E., Maesaka, J. K. (2013) Demonstration of natriuretic activity in urine of neurosurgical patients with renal salt wasting. F1000 Research, 2. p. 126. ISSN 20461402 (ISSN)

Fein, M. R., Egeblad, M. (2013) Caught in the act: revealing the metastatic process by live imaging. Disease Models and Mechanisms, 6 (3). pp. 580-93. ISSN 1754-8411 (Electronic)1754-8403 (Linking)

Chin, L., De Sauvage, F., Egeblad, M., Olive, K. P., Tuveson, D., Weiss, W. (2013) Recapitulating human cancer in a mouse. Nature Biotechnology, 31 (5). pp. 392-395. ISSN 10870156

Nakasone, E., Askautrud, H., Kees, T., Park, J., Fein, M., Egeblad, M. (2013) Imaging contributions of the microenvironment to chemoresistance. Journal of Nuclear Medicine, 54 (Supple). p. 31. ISSN 0161-5505

Nakasone, E. S., Askautrud, H. A., Egeblad, M. (2013) Live imaging of drug responses in the tumor microenvironment in mouse models of breast cancer. Journal of Visualized Experiments (73). ISSN 1940-087X (Electronic)1940-087X (Linking)

Nakasone, E. S., Askautrud, H. A., Kees, T., Park, J. H., Plaks, V., Ewald, A. J., Fein, M., Rasch, M. G., Tan, Y. X., Qiu, J., Park, J., Sinha, P., Bissell, M. J., Frengen, E., Werb, Z., Egeblad, M. (2012) Imaging Tumor-Stroma Interactions during Chemotherapy Reveals Contributions of the Microenvironment to Resistance. Cancer Cell, 21 (4). pp. 488-503. ISSN 1535-6108

Engelhardt, J. J., Boldajipour, B., Beemiller, P., Pandurangi, P., Sorensen, C., Werb, Z., Egeblad, M., Krummel, M. F (2012) Marginating Dendritic Cells of the Tumor Microenvironment Cross-Present Tumor Antigens and Stably Engage Tumor-Specific T Cells. Cancer Cell, 21 (3). pp. 402-417. ISSN 1535-6108

Kees, T., Egeblad, M. (2011) Innate Immune Cells in Breast Cancer - From Villains to Heroes? Journal of Mammary Gland Biology and Neoplasia, 16 (3). pp. 189-203. ISSN 1573-7039 (Electronic)1083-3021 (Linking)

Ewald, A. J., Werb, Z., Egeblad, M. (2011) Dynamic, Long-Term In Vivo Imaging of Tumor–Stroma Interactions in Mouse Models of Breast Cancer Using Spinning-Disk Confocal Microscopy. Cold Spring Harbor Protocols, 2011 (2).

Ewald, A. J., Werb, Z., Egeblad, M. (2011) Monitoring of vital signs for long-term survival of mice under anesthesia. Cold Spring Harbor Protocols, 2011 (2). ISSN 1559-6095

Ewald, A. J., Werb, Z., Egeblad, M. (2011) Preparation of mice for long-term intravital imaging of the mammary gland. Cold Spring Harbor Protocols, 2011 (2). ISSN 1559-6095

Egeblad, M., Rasch, M. G., Weaver, V. M. (2010) Dynamic interplay between the collagen scaffold and tumor evolution. Current Opinion in Cell Biology, 22 (5). pp. 697-706. ISSN 0955-0674

Egeblad, M., Nakasone, E. S., Werb, Z. (2010) Tumors as Organs: Complex Tissues that Interface with the Entire Organism. Developmental Cell, 18 (6). pp. 884-901. ISSN 1534-5807

Sounni, N. E., Dehne, K., Van Kempen, L., Egeblad, M., Affara, N. I., Cuevas, I., Wiesen, J., Junankar, S., Korets, L., Lee, J., Shen, J., Morrison, C. J., Overall, C. M., Krane, S. M., Werb, Z., Boudreau, N., Coussens, L. M. (2010) Stromal regulation of vessel stability by MMP14 and TGFbeta. Disease Models and Mechanisms, 3 (5-6). pp. 317-332. ISSN 17548403 (ISSN)

Levental, K. R., Yu, H., Kass, L., Lakins, J. N., Egeblad, M., Erler, J. T., Fong, S. F. T., Csiszar, K., Giaccia, A., Weninger, W., Yamauchi, M., Gasser, D. L., Weaver, V. M. (2009) Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling. Cell, 139 (5). pp. 891-906. ISSN 00928674 (ISSN)

Kouros-Mehr, H., Bechis, S. K., Slorach, E. M., Littlepage, L. E., Egeblad, M., Ewald, A. J., Pai, S. Y., Ho, I. C., Werb, Z. (2008) GATA-3 Links Tumor Differentiation and Dissemination in a Luminal Breast Cancer Model. Cancer Cell, 13 (2). pp. 141-152. ISSN 15356108 (ISSN)

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy. Disease Models and Mechanisms, 1 (2-3). pp. 155-167. ISSN 17548403 (ISSN)

Egeblad, M., Shen, H. C. J., Behonick, D. J., Wilmes, L., Eichten, A., Korets, L. V., Kheradmand, F., Werb, Z., Coussens, L. M. (2007) Type I collagen is a genetic modifier of matrix metalloproteinase 2 in murine skeletal development. Developmental Dynamics, 236 (6). pp. 1683-1693. ISSN 10588388 (ISSN)

Määttä, J. A., Sundvall, M., Junttila, T. T., Peri, L., Laine, V. J. O., Isola, J., Egeblad, M., Elenius, K. (2006) Proteolytic cleavage and phosphorylation of a tumor-associated ErbB4 isoform promote ligand-independent survival and cancer cell growth. Molecular Biology of the Cell, 17 (1). pp. 67-79. ISSN 10591524 (ISSN)

Littlepage, L. E., Egeblad, M., Werb, Z. (2005) Coevolution of cancer and stromal cellular responses. Cancer Cell, 7 (6). pp. 499-500. ISSN 15356108 (ISSN)

Morimoto-Tomita, M., Uchimura, K., Bistrup, A., Lum, D. H., Egeblad, M., Boudreau, N., Werb, Z., Rosen, S. D. (2005) Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer. Neoplasia, 7 (11). pp. 1001-1010. ISSN 15228002 (ISSN)

Egeblad, M., Littlepage, L. E., Werb, Z. (2005) The fibroblastic coconspirator in cancer progression. Cold Spring Harbor Symposia on Quantitative Biology, 70. pp. 383-388. ISSN 00917451 (ISSN)

Sundvall, M., Maatta, J. A., Peri, L., Junttila, T. T., Egeblad, M., Elenius, K. (2004) Ligand-independent signaling by a tumor-associated isoform of ErbB4. Cancer Research, 64 (7 Supp). p. 23. ISSN 1078-0432

Van Kempen, L. C. L. T., Meier, F., Egeblad, M., Kersten-Niessen, M. J. F., Garbe, C., Weidle, U. H., Van Muijen, G. N. P., Herlyn, M., Bloemers, H. P. J., Swart, G. W. M. (2004) Truncation of activated leukocyte cell adhesion molecule: A gateway to melanoma metastasis. Journal of Investigative Dermatology, 122 (5). pp. 1293-1301. ISSN 0022202X (ISSN)

Man, A. K., Young, L. J. T., Tynan, J. A., Lesperance, J., Egeblad, M., Werb, Z., Hauser, C. A., Muller, W. J., Cardiff, R. D., Oshima, R. G. (2003) Ets2-Dependent Stromal Regulation of Mouse Mammary Tumors. Molecular and Cellular Biology, 23 (23). pp. 8614-8625. ISSN 02707306 (ISSN)

Li, Y., Welm, B., Podsypanina, K., Huang, S., Chamorro, M., Zhang, X., Rowlands, T., Egeblad, M., Cowin, P., Werb, Z., Tan, L. K., Rosen, J. M., Varmus, H. E. (2003) Evidence that transgenes encoding components of the Wnt signaling pathway preferentially induce mammary cancers from progenitor cells. Proceedings of the National Academy of Sciences of the United States of America, 100 (26). pp. 15853-15858. ISSN 00278424 (ISSN)

Egeblad, M., Kouros-Mehr, H., Welm, B. E., Ortega, N., Cunha, G. R., Werb, Z. (2002) MMP-9 in mouse mammary cancer. Molecular Biology of the Cell, 13. 209A-210A. ISSN 1059-1524

Egeblad, M., Werb, Z. (2002) New functions for the matrix metalloproteinases in cancer progression. Nature Reviews Cancer, 2 (3). pp. 161-174. ISSN 1474175X (ISSN)

Egeblad, M., Mortensen, O. H., Jaattela, M. (2001) Truncated ErbB2 receptor enhances ErbB1 signaling and induces reversible, ERK-independent loss of epithelial morphology. International Journal of Cancer, 94 (2). pp. 185-91. ISSN 0020-7136 (Print)0020-7136

Karpanen, T., Egeblad, M., Karkkainen, M. J., Kubo, H., Yla-Herttuala, S., Jaattela, M., Alitalo, K. (2001) Vascular endothelial growth factor C promotes tumor lymphangiogenesis and intralymphatic tumor growth. Cancer Research, 61 (5). pp. 1786-90. ISSN 0008-5472 (Print)0008-5472

Egeblad, M., Mortensen, O. H., van Kempen, L. C., Jaattela, M. (2001) BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells. Biochemical and biophysical research communications, 281 (1). pp. 25-31. ISSN 0006-291X (Print)0006-291x

Egeblad, M., Jaattela, M. (2000) Cell death induced by TNF or serum starvation is independent of ErbB receptor signaling in MCF-7 breast carcinoma cells. International Journal of Cancer, 86 (5). pp. 617-25. ISSN 0020-7136 (Print)0020-7136

Larsen, S. S., Egeblad, M., Jaattela, M., Lykkesfeldt, A. E. (1999) Acquired antiestrogen resistance in MCF-7 human breast cancer sublines is not accomplished by altered expression of receptors in the ErbB-family. Breast cancer research and treatment, 58 (1). pp. 41-56. ISSN 0167-6806 (Print)0167-6806

Jaattela, M., Wissing, D., Kokholm, K., Kallunki, T., Egeblad, M. (1998) Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases. EMBO Journal, 17 (21). pp. 6124-34. ISSN 0261-4189 (Print)0261-4189

Wissing, D., Mouritzen, H., Egeblad, M., Poirier, G. G., Jaattela, M. (1997) Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 94 (10). pp. 5073-7. ISSN 0027-8424 (Print)0027-8424

Book Section

Ewald, A., Werb, Z., Egeblad, M. (2009) Dynamic, Long-Term, In Vivo Imaging of Tumor-Stroma Interactions in Mouse Models of Breast Cancer Using Spinning-Disk Confocal Microscopy. In: Live Cell Imaging: A Laboratory Manual, Second Edition. Cold Spring Harbor Laboratory Press, New York, pp. 419-439. ISBN 9780879698935

Thesis

Nakasone, Elizabeth (2012) A Stromal CCL2/CCR2 Signaling Axis Regulates Chemotherapeutic Response in a Mouse Model of Breast Cancer. PhD thesis, Cold Spring Harbor Laboratory.

Video

Egeblad, M. (2012) c-fms+ myeloid cells respond to injection of E. coli in a mammary gland. [Video] (Unpublished)

Egeblad, M. (2011) Talk from Mikala Egeblad at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)

Sounni, N. E., Dehne, K., Van Kempen, L., Egeblad, M., Affara, N. I., Cuevas, I., Wiesen, J., Junankar, S., Korets, L., Lee, J., Shen, J., Morrison, C. J., Overall, C. M., Krane, S. M., Werb, Z., Boudreau, N., Coussens, L. M. (2010) Extravasation and stromal cell uptake of fluorescent dextran in tumors. [Video]

Egeblad, M., Nakasone, E. S., Werb, Z. (2010) Migration of CXCR6+ activated/memory T-cells in the tumor microenvironment. [Video]

Egeblad, M., Nakasone, E. S., Werb, Z. (2010) Migration of CXCR6+ activated/memory T-cells is stopped in response to hypoxia. [Video]

Ewald, A. J., Werb, Z., Egeblad, M. (2009) Myeloid cells extravasate and infiltrate late carcinoma lesions. [Video]

Ewald, A. J., Werb, Z., Egeblad, M. (2009) c-fms+ myeloid cells migrate in response to wounding on the surface of a normal mammary gland. [Video]

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) CD11c+ dendritic-like cells migrate at the tumor-stroma border. [Video]

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) Carcinoma-associated fibroblasts in different tumor microenvironments. [Video]

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) Foxp3+ regulatory T cells migrate along blood vessels and at the tumor-stroma border. [Video]

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) Gr1+ myeloid cells are a patrolling subpopulation of the tumor-infiltrating myeloid cells. [Video]

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) Infiltration and migration of c-fms+ myeloid cells in the tumor microenvironment. [Video]

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) Migration of Foxp3+ regulatory T-lymphocytes is stopped in response to hypoxia. [Video]

Egeblad, M., Ewald, A. J., Askautrud, H. A., Truitt, M. L., Welm, B. E., Bainbridge, E., Peeters, G., Krummel, M. F., Werb, Z. (2008) c-fms+ myeloid cells migrate in the normal mammary gland. [Video]

This list was generated on Wed Apr 26 01:57:03 2017 EDT.
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