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Shao, L., Lu, B., Wen, Z., Teng, S., Wang, L., Zhao, Y., Wang, L., Ishizuka, K., Xu, X., Sawa, A., Song, H., Ming, G., Zhong, Y. (July 2017) Disrupted-in-Schizophrenia-1 (DISC1) protein disturbs neural function in multiple disease-risk pathways. Hum Mol Genet, 26 (14). pp. 2634-2648. ISSN 0964-6906

Beshel, J., Dubnau, J., Zhong, Y. (January 2017) A Leptin Analog Locally Produced in the Brain Acts via a Conserved Neural Circuit to Modulate Obesity-Linked Behaviors in Drosophila. Cell Metab, 25 (1). pp. 208-217. ISSN 1932-7420 (Electronic)1550-4131 (Linking)

Shuai, Y., Hirokawa, A., Ai, Y., Zhang, M., Li, W., Zhong, Y. (December 2015) Dissecting neural pathways for forgetting in Drosophila olfactory aversive memory. Proc Natl Acad Sci U S A, 112 (48). E6663-72. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Beshel, J., Zhong, Y. (September 2015) Alterations in Brain-derived Leptin-homolog Unpaired 1 Lead to Obesity Phenotypes in Drosophila through Regulation of Food Odor Value Signaling. Chemical Senses, 40 (7). pp. 549-550. ISSN 0379-864X

Lu, B. Y., Shao, L. S., Feng, S. X., Wang, T., Zhong, Y. (January 2014) The beta-alanyl-monoamine synthase ebony is regulated by schizophrenia susceptibility gene dysbindin in Drosophila. Science China-Life Sciences, 57 (1). pp. 46-51. ISSN 1674-7305

Beshel, J., Zhong, Y. (October 2013) Graded Encoding of Food Odor Value in the Drosophila Brain. Journal of Neuroscience, 33 (40). pp. 15693-15704. ISSN 0270-6474

Wang, L., Liang, B., Zhong, Y. (September 2013) Reduced EGFR level potentially mediates the A beta 42-induced neuronal loss in transgenic fruit fly and mouse. Protein & Cell, 4 (9). pp. 647-649. ISSN 1674-800X

Huang, C., Wang, P., Xie, Z., Wang, L., Zhong, Y. (July 2013) The differential requirement of mushroom body α/β subdivisions in long-term memory retrieval in Drosophila. Protein and Cell, 4 (7). pp. 512-519. ISSN 1674800X

Zhao, J., Lu, Y., Zhao, X., Yao, X., Shuai, Y., Huang, C., Wang, L., Jeong, S. H., Zhong, Y. (June 2013) Dissociation of rugose-dependent short-term memory component from memory consolidation in Drosophila. Genes, Brain and Behavior, 12 (6). pp. 626-632. ISSN 16011848

Huang, C. , Zheng, X., Zhao, H., Li, M., Wang, P. , Xie, Z., Wang, L., Zhong, Y. (November 2012) A Permissive Role of Mushroom Body α/β Core Neurons in Long-Term Memory Consolidation in Drosophila. Current Biology, 22 (21). pp. 1981-1989. ISSN 0960-9822

Wang, L., Chiang, H. C., Wu, W. J., Liang, B., Xie, Z. L., Yao, X. S., Ma, W. W., Du, S. W., Zhong, Y. (October 2012) Epidermal growth factor receptor is a preferred target for treating Amyloid-beta-induced memory loss. Proceedings of the National Academy of Sciences of the United States of America, 109 (41). pp. 16743-16748. ISSN 0027-8424

Lang, M. L., Wang, L., Fan, Q. W., Xiao, G. R., Wang, X. X., Zhong, Y., Zhou, B. (April 2012) Genetic Inhibition of Solute-Linked Carrier 39 Family Transporter 1 Ameliorates A beta Pathology in a Drosophila Model of Alzheimer's Disease. PLoS Genetics, 8 (4). pp. 623-639. ISSN 1553-7390

Shuai, Y. C., Hu, Y., Qin, H. T., Campbell, R. A. A., Zhong, Y. (December 2011) Distinct molecular underpinnings of Drosophila olfactory trace conditioning. Proceedings of the National Academy of Sciences of the United States of America, 108 (50). pp. 20201-20206. ISSN 0027-8424

Shuai, Y. C., Zhang, Y. S., Gao, L. W., Zhong, Y. (March 2011) Stress Resistance Conferred by Neuronal Expression of Dominant-Negative Rac in Adult Drosophila melanogaster. Journal of Neurogenetics, 25 (1-2). pp. 35-39. ISSN 0167-7063

Shao, L., Shuai, Y., Wang, J., Feng, S., Lu, B., Li, Z., Zhao, Y., Wang, L., Zhong, Y. (2011) Schizophrenia susceptibility gene dysbindin regulates glutamatergic and dopaminergic functions via distinctive mechanisms in Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 108 (46). pp. 18831-18836. ISSN 00278424 (ISSN)

Shuai, Y. C., Zhong, Y. (June 2010) Forgetting and small G protein Rac. Protein and Cell, 1 (6). pp. 503-506. ISSN 1674800X (ISSN)

Chiang, H-C., Wang, L., Xie, Z. L., Yau, A., Zhong, Y. (April 2010) PI3 kinase signaling is involved in A beta-induced memory loss in Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 107 (15). pp. 7060-7065. ISSN 0027-8424

Shuai, Y. C., Lu, B., Hu, Y., Wang, L., Sun, K., Zhong, Y. (February 2010) Forgetting Is Regulated through Rac Activity in Drosophila. Cell, 140 (4). pp. 579-589.

Pagani, M. R., Oishi, K., Gelb, B. D., Zhong, Y. (October 2009) The phosphatase SHP2 regulates the spacing effect for long-term memory induction. Cell, 139 (1). pp. 186-98. ISSN 1097-4172 (Electronic)

Song, Q., Sun, K., Shuai, Y. C., Lin, R., You, W., Wang, L., Zhong, Y. (July 2009) Suppressor of hairless is required for long-term memory formation in drosophila. Journal of Neurogenetics, 23 (4). pp. 405-411.

Chiang, H-C., Iijima, K., Hakker, I., Zhong, Y. (June 2009) Distinctive roles of different {beta}-amyloid 42 aggregates in modulation of synaptic functions. FASEB J., 23 (6). pp. 1969-1977.

de Bivort, B. L., Guo, H.- F., Zhong, Y. (April 2009) Notch signaling is required for activity-dependent synaptic plasticity at the Drosophila neuromuscular junction. J Neurogenet, 23 (4). pp. 395-404. ISSN 1563-5260 (Electronic)

Zhao, H., Zheng, X., Yuan, X., Wang, L., Wang, X., Zhong, Y., Xie, Z., Tully, T. (January 2009) ben Functions with Scamp during Synaptic Transmission and Long-Term Memory Formation in Drosophila. J Neurosci, 29 (2). pp. 414-424.

Mamiya, A., Beshel, J., Xu, C., Zhong, Y. (December 2008) Neural Representations of Airflow in Drosophila Mushroom Body. PLoS ONE, 3 (12). e4063. ISSN 1932-6203 (Electronic)

Iijima-Ando, K., Hearn, S. A., Granger, L., Shenton, C., Gatt, A., Chiang, H. C., Hakker, I., Zhong, Y., Iijima, K. (July 2008) Overexpression of neprilysin reduces Alzheimer amyloid-beta 42 (A beta 42)-induced neuron loss and intraneuronal A beta 42 deposits but causes a reduction in cAMP-responsive element-binding protein-mediated transcription, age-dependent axon pathology, and premature death in Drosophila. Journal of Biological Chemistry, 283 (27). pp. 19066-19076. ISSN 0021-9258

Wang, Y., Mamiya, A., Chiang, A. S., Zhong, Y. (April 2008) Imaging of an early memory trace in the Drosophila mushroom body. J Neurosci, 28 (17). pp. 4368-76. ISSN 1529-2401 (Electronic)

Iijima, K., Chiang, H. C., Hearn, S. A., Hakker, I., Gatt, A., Shenton, C., Granger, L., Leung, A., Iijima-Ando, K., Zhong, Y. (February 2008) A beta 42 Mutants with Different Aggregation Profiles Induce Distinct Pathologies in Drosophila. PLoS ONE, 3 (2). e1703. ISSN 1932-6203 (Electronic)

Lu, Y., Lv, Y., Ye, Y., Wang, Y., Hong, Y., Fortini, M. E., Zhong, Y., Xie, Z. (August 2007) A role for presenilin in post-stress regulation: effects of presenilin mutations on Ca2+ currents in Drosophila. Faseb Journal, 21 (10). pp. 2368-2378. ISSN 1530-6860 (Electronic)

Ho, I. S., Hannan, F., Guo, H.-F., Hakker, I., Zhong, Y. (June 2007) Distinct functional domains of neurofibromatosis type 1 regulate immediate versus long-term memory formation. J Neurosci, 27 (25). pp. 6852-7. ISSN 1529-2401 (Electronic)

Qian, M., Pan, G., Sun, L., Feng, C., Xie, Z., Tully, T., Zhong, Y. (2007) Receptor-like tyrosine phosphatase PTP10D is required for long-term memory in Drosophila. Journal of Neuroscience, 27 (16). pp. 4396-4402. ISSN 02706474 (ISSN)

Wang, Yalin, Zhong, Yi (July 2006) Imaging of learning & memory associated changes in the mushroom body within the adult brain of Drosophila. Journal of Neurogenetics, 20 (3-4). pp. 254-255. ISSN 0167-7063

Guo, H. F., Zhong, Y. (April 2006) Requirement of Akt to mediate long-term synaptic depression in Drosophila. J Neurosci, 26 (15). pp. 4004-14. ISSN 1529-2401 (Electronic)

Hannan, F., Ho, I., Tong, J. J., Zhu, Y., Nurnberg, P., Zhong, Y. (April 2006) Effect of neurofibromatosis type I mutations on a novel pathway for adenylyl cyclase activation requiring neurofibromin and Ras. Hum Mol Genet, 15 (7). pp. 1087-98. ISSN 0964-6906 (Print)

Ge, X. C., Hannan, F., Xie, Z. L., Feng, C. H., Tully, T., Zhou, H. M., Xie, Z. P., Zhong, Y. (July 2004) Notch signaling in Drosophila long-term memory formation. Proceedings of the National Academy of Sciences of the United States of America, 101 (27). pp. 10172-10176. ISSN 0027-8424

Wang, Y. L., Guo, H. F., Pologruto, T. A., Hannan, F., Hakker, I., Svoboda, K., Zhong, Y. (July 2004) Stereotyped odor-evoked activity in the mushroom body of Drosophila revealed by green fluorescent protein-based Ca2+ imaging. Journal of Neuroscience, 24 (29). pp. 6507-6514. ISSN 0270-6474

Iijima, K., Liu, H. P., Chiang, A. S., Hearn, S. A., Konsolaki, M., Zhong, Y. (April 2004) Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease. Proc Natl Acad Sci U S A, 101 (17). pp. 6623-8. ISSN 0027-8424 (Print)

Wang, Y., Zhong, Y. (February 2004) TARGETing "when" and "where". Sci STKE, 2004 (220). pe5. ISSN 1525-8882 (Electronic)

Zhong, Y., Wu, C. F. (February 2004) Neuronal activity and adenylyl cyclase in environment-dependent plasticity of axonal outgrowth in Drosophila. Journal of Neuroscience, 24 (6). pp. 1439-1445. ISSN 0270-6474

Wang, Y. L., Chiang, A. S., Xia, S. Z., Kitamoto, T., Tully, T., Zhong, Y. (October 2003) Blockade of neurotransmission in Drosophila mushroom bodies impairs odor attraction, but not repulsion. Current Biology, 13 (21). pp. 1900-1904. ISSN 0960-9822

Tong, J. Y., Hannan, F., Zhu, Y. H., Bernards, A., Zhong, Y. (February 2002) Neurofibromin regulates G protein-stimulated adenylyl cyclase activity. Nature Neuroscience, 5 (2). pp. 95-96. ISSN 1097-6256

Wang, Y. L., Wright, N. J. D., Guo, H. F., Xie, Z. P., Svoboda, K., Malinow, R., Smith, D. P., Zhong, Y. (January 2001) Genetic manipulation of the odor-evoked distributed neural activity in the Drosophila mushroom body. Neuron, 29 (1). pp. 267-276. ISSN 0896-6273

Guo, H. F., Tong, J. Y., Hannan, F., Luo, L., Zhong, Y. (February 2000) A neurofibromatosis-1-regulated pathway is required for learning in Drosophila. Nature, 403 (6772). pp. 895-898. ISSN 0028-0836

Hannan, F., Zhong, Y. (1999) Second messenger systems underlying plasticity at the neuromuscular junction. Int Rev Neurobiol, 43. pp. 119-38. ISSN 0074-7742 (Print)

Wright, N. J., Zhong, Y. (January 1998) Serotonin-sensitive leakage channel in Drosophila central neurons. J Neurobiol, 34 (1). pp. 83-95. ISSN 0022-3034 (Print)

Guo, H. F., The, I., Hannan, F., Bernards, A., Zhong, Y. (May 1997) Requirement of Drosophila NF1 for activation of adenylyl cyclase by PACAP38-like neuropeptides. Science, 276 (5313). pp. 795-8. ISSN 0036-8075 (Print)

The, I., Hannigan, G. E., Cowley, G. S., Reginald, S., Zhong, Y., Gusella, J. F., Hariharan, I. K., Bernards, A. (1997) Rescue of a Drosophila NF1 mutant phenotype by protein kinase A. Science, 276 (5313). pp. 791-794. ISSN 00368075 (ISSN)

Zhong, Y. (December 1996) Genetic dissection of signal transduction mechanisms underlying PACAP-like neuropeptide transmission in Drosophila: synergy of cAMP and Ras/Raf pathways. Ann N Y Acad Sci, 805. 67-79; discussion 79. ISSN 0077-8923 (Print)

Zhong, Y. (1996) Behavior-specific genes? Trends in Genetics, 12 (3). pp. 116-117. ISSN 01689525 (ISSN)

Zhong, Y., Shanley, J. (October 1995) Altered nerve terminal arborization and synaptic transmission in Drosophila mutants of cell adhesion molecule fasciclin I. J Neurosci, 15 (10). pp. 6679-87. ISSN 0270-6474 (Print)

Zhong, Y. (June 1995) Mediation of PACAP-like neuropeptide transmission by coactivation of Ras/Raf and cAMP signal transduction pathways in Drosophila. Nature, 375 (6532). pp. 588-92. ISSN 0028-0836 (Print)

Zhong, Y., Pena, L. A. (March 1995) A novel synaptic transmission mediated by a PACAP-like neuropeptide in Drosophila. Neuron, 14 (3). pp. 527-36. ISSN 0896-6273 (Print)

Wright, N. J., Zhong, Y. (February 1995) Characterization of K+ currents and the cAMP-dependent modulation in cultured Drosophila mushroom body neurons identified by lacZ expression. J Neurosci, 15 (2). pp. 1025-34. ISSN 0270-6474 (Print)

Griffith, L. C., Wang, J., Zhong, Y., Wu, C. F., Greenspan, R. J. (1994) Calcium/calmodulin-dependent protein kinase II and potassium channel subunit Eag similarly affect plasticity in Drosophila. Proceedings of the National Academy of Sciences of the United States of America, 91 (21). pp. 10044-10048. ISSN 00278424 (ISSN)

Zhong, Y., Wu, C. F. (November 1993) Modulation of different K+ currents in Drosophila: a hypothetical role for the Eag subunit in multimeric K+ channels. J Neurosci, 13 (11). pp. 4669-79. ISSN 0270-6474 (Print)

Zhong, Y., Wu Chun, F. (1993) Differential modulation of potassium currents by cAMP and its long-term and short-term effects: dunce and rutabaga mutants of Drosophila. J.NEUROGENET., 9 (1). pp. 15-27. ISSN 01677063 (ISSN)

Zhong, Y., Budnik, V., Wu, C. F. (February 1992) Synaptic plasticity in Drosophila memory and hyperexcitable mutants: role of cAMP cascade. J Neurosci, 12 (2). pp. 644-51. ISSN 0270-6474 (Print)

Zhong, Y., Wu, C. F. (June 1991) Alteration of four identified K+ currents in Drosophila muscle by mutations in eag. Science, 252 (5012). pp. 1562-4. ISSN 0036-8075 (Print)

Zhong, Y., Wu, C. F. (January 1991) Altered synaptic plasticity in Drosophila memory mutants with a defective cyclic AMP cascade. Science, 251 (4990). pp. 198-201. ISSN 0036-8075 (Print)

Budnik, V., Zhong, Y., Wu, C. F. (November 1990) Morphological plasticity of motor axons in Drosophila mutants with altered excitability. J Neurosci, 10 (11). pp. 3754-68. ISSN 0270-6474 (Print)

Wu, C. F., Tsai, M. C., Chen, M. L., Zhong, Y., Singh, S., Lee, C. Y. (November 1989) Actions of dendrotoxin on K+ channels and neuromuscular transmission in Drosophila melanogaster, and its effects in synergy with K+ channel-specific drugs and mutations. J Exp Biol, 147 (1). pp. 21-41. ISSN 0022-0949 (Print)

Book Section

Wang, Yalin, Dubnau, Josh, Tully, Tim, Zhong, Yi (2007) Chapter 3 - Genetics in learning and memory. In: Neurobiology of Learning and Memory (Second Edition). Academic Press, Burlington, pp. 103-127. ISBN 978-0-12-372540-0

Video

Zhong, Y. (November 2011) Talk from Yi Zhong at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)