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Qiu, Yijian, Stamatatos, Olivia T, Hu, Qingting, Ruiter Swain, Jed, Russo, Suzanne, Sann, Ava, Costa, Ana SH, Violante, Sara, Spector, David L, Cross, Justin R, Lukey, Michael J (August 2024) The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade. Nature Metabolism, 6 (8). pp. 1529-1548. ISSN 2522-5812 (Public Dataset)

Klingbeil, Olaf, Skopelitis, Damianos, Tonelli, Claudia, Yoshimoto, Toyoki, Alpsoy, Aktan, Panepinto, Maria C, Minicozzi, Francesca, Merrill, Joseph R, Cafiero, Amanda M, Aggarwal, Disha, Russo, Suzanne, Ha, Taehoon, Demerdash, Osama E, Wee, Tse-Luen, Spector, David L, Lyons, Scott K, Tuveson, David A, Cifani, Paolo, Vakoc, Christopher R (July 2024) MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer. Cancer Discovery. ISSN 2159-8274 (Public Dataset)

Maia-Silva, Diogo, Cunniff, Patrick J, Schier, Allison C, Skopelitis, Damianos, Trousdell, Marygrace C, Moresco, Philip, Gao, Yuan, Kechejian, Vahag, He, Xue-Yan, Sahin, Yunus, Wan, Ledong, Alpsoy, Aktan, Liverpool, Jynelle, Krainer, Adrian R, Egeblad, Mikala, Spector, David L, Fearon, Douglas T, Dos Santos, Camila O, Taatjes, Dylan J, Vakoc, Christopher R (June 2024) Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma. Nature Genetics. ISSN 1061-4036

Klingbeil, Olaf, Skopelitis, Damianos, Tonelli, Claudia, Alpsoy, Aktan, Minicozzi, Francesca, Aggarwal, Disha, Russo, Suzanne, Ha, Taehoon, Demerdash, Osama E, Spector, David L, Tuveson, David A, Cifani, Paolo, Vakoc, Christopher R (February 2024) MARK2/MARK3 kinases are catalytic co-dependencies of YAP/TAZ in human cancer. bioRxiv. (Submitted)

He, Xue-Yan, Gao, Yuan, Ng, David, Michalopoulou, Evdokia, George, Shanu, Adrover, Jose M, Sun, Lijuan, Albrengues, Jean, Daßler-Plenker, Juliane, Han, Xiao, Wan, Ledong, Wu, Xiaoli Sky, Shui, Longling S, Huang, Yu-Han, Liu, Bodu, Su, Chang, Spector, David L, Vakoc, Christopher R, Van Aelst, Linda, Egeblad, Mikala (February 2024) Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment. Cancer Cell. ISSN 1535-6108

Balasooriya, Gayan I, Wee, Tse-Luen, Spector, David L (October 2023) A sub-set of guanine- and cytosine-rich genes are actively transcribed at the nuclear Lamin B1 region. bioRxiv. (Public Dataset) (Submitted)

Hazra, Rasmani, Utama, Raditya, Naik, Payal, Dobin, Alexander, Spector, David L (October 2023) Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA sequencing datasets. Stem Cell Reports. ISSN 2213-6711

Mousset, Alexandra, Lecorgne, Enora, Bourget, Isabelle, Lopez, Pascal, Jenovai, Kitti, Cherfils-Vicini, Julien, Dominici, Chloé, Rios, Géraldine, Girard-Riboulleau, Cédric, Liu, Bodu, Spector, David L, Ehmsen, Sidse, Renault, Shufang, Hego, Caroline, Mechta-Grigoriou, Fatima, Bidard, François-Clément, Terp, Mikkel Green, Egeblad, Mikala, Gaggioli, Cédric, Albrengues, Jean (April 2023) Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation. Cancer Cell, 41 (4). 757-775.e10. ISSN 1535-6108 (Public Dataset)

Balasooriya, Gayan I, Spector, David L (April 2023) Allele pairing at Sun1-enriched domains at the nuclear periphery via T1A3 tandem DNA repeats. bioRxiv. (Public Dataset) (Submitted)

Aggarwal, Disha, Russo, Suzanne, Naik, Payal, Bhatia, Sonam, Spector, David L (February 2023) Establishment and Culture of Patient-Derived Breast Organoids. Journal of Visualized Experiments (192). ISSN 1940-087X

Hazra, Rasmani, Utama, Raditya, Naik, Payal, Dobin, Alexander, Spector, David L (January 2023) Identification of glioblastoma stem cell-associated lncRNAs using single-cell RNA-sequencing datasets. bioRxiv. (Submitted)

Mattick, John S, Amaral, Paulo P, Carninci, Piero, Carpenter, Susan, Chang, Howard Y, Chen, Ling-Ling, Chen, Runsheng, Dean, Caroline, Dinger, Marcel E, Fitzgerald, Katherine A, Gingeras, Thomas R, Guttman, Mitchell, Hirose, Tetsuro, Huarte, Maite, Johnson, Rory, Kanduri, Chandrasekhar, Kapranov, Philipp, Lawrence, Jeanne B, Lee, Jeannie T, Mendell, Joshua T, Mercer, Timothy R, Moore, Kathryn J, Nakagawa, Shinichi, Rinn, John L, Spector, David L, Ulitsky, Igor, Wan, Yue, Wilusz, Jeremy E, Wu, Mian (January 2023) Long non-coding RNAs: definitions, functions, challenges and recommendations. Nature Reviews Molecular Cell Biology. ISSN 1471-0072

Yu, Allen T, Aggarwal, Disha, Pappin, Darryl, Spector, David L (December 2022) Single Oligonucleotide Capture of RNA And Temperature Elution Series ( SOCRATES ) for Identification of RNA-binding Proteins. Bio-protocol, 12 (24). e4572. ISSN 2331-8325

Moravec, Jiří C, Lanfear, Robert, Spector, David L, Diermeier, Sarah D, Gavryushkin, Alex (December 2022) Testing for Phylogenetic Signal in Single-Cell RNA-Seq Data. Journal of Computational Biology. ISSN 1066-5277

Hazra, Rasmani, Brine, Lily, Garcia, Libia, Benz, Brian, Chirathivat, Napon, Shen, Michael M, Wilkinson, John Erby, Lyons, Scott K, Spector, David L (November 2022) Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment. Developmental Cell, 57 (21). 2450-2468.e7. ISSN 1534-5807

Balasooriya, Gayan I, Spector, David L (October 2022) Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage. Nature Communications, 13 (1). p. 5984. ISSN 2041-1723

Hazra, Rasmani, Spector, David L (October 2022) Simultaneous visualization of RNA transcripts and proteins in whole-mount mouse preimplantation embryos using single-molecule fluorescence in situ hybridization and immunofluorescence microscopy. Frontiers in Cell and Developmental Biology, 10. ISSN 2296-634X

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Plenker, Dennis, Tuveson, David A, Rishi, Arvind, Wilkinson, John E, McCombie, W Richard, Kostroff, Karen, Spector, David L (February 2022) Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics. Cancer Research. ISSN 0008-5472

Balasooriya, Gayan, Spector, David (2022) Allele-specific differential regulation of monoallelically expressed autosomal genes in the cardiac lineage. bioRxiv. (Submitted)

Cable, Jennifer, Heard, Edith, Hirose, Tetsuro, Prasanth, Kannanganattu V, Chen, Ling-Ling, Henninger, Jonathan E, Quinodoz, Sofia A, Spector, David L, Diermeier, Sarah D, Porman, Allison M, Kumar, Dhiraj, Feinberg, Mark W, Shen, Xiaohua, Unfried, Juan Pablo, Johnson, Rory, Chen, Chun-Kan, Wilusz, Jeremy E, Lempradl, Adelheid, McGeary, Sean E, Wahba, Lamia, Pyle, Anna Marie, Hargrove, Amanda E, Simon, Matthew D, Marcia, Marco, Przanowska, Róża K, Chang, Howard Y, Jaffrey, Samie R, Contreras, Lydia M, Chen, Qi, Shi, Junchao, Mendell, Joshua T, He, Lin, Song, Erwei, Rinn, John L, Lalwani, Mukesh Kumar, Kalem, Murat Can, Chuong, Edward B, Maquat, Lynne E, Liu, Xuhang (November 2021) Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences. ISSN 0077-8923

Sun, Lijuan, Kees, Tim, Almeida, Ana Santos, Liu, Bodu, He, Xue-Yan, Ng, David, Han, Xiao, Spector, David L, McNeish, Iain A, Gimotty, Phyllis, Adams, Sylvia, Egeblad, Mikala (September 2021) Activating a collaborative innate-adaptive immune response to control metastasis. Cancer Cell. ISSN 1535-6108

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter A, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Rishi, Arvind, Wilkinson, John Erby, McCombie, William Richard, Kostroff, Karen, Spector, David L (August 2021) Patient-derived triple negative breast cancer organoids provide robust model systems that recapitulate tumor intrinsic characteristics. BioRxiv.

Yu, Allen T, Berasain, Carmen, Bhatia, Sonam, Rivera, Keith, Liu, Bodu, Rigo, Frank, Pappin, Darryl J, Spector, David L (May 2021) PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR. eLife, 10. ISSN 2050-084X

Chang, KC, Spector, DL (January 2021) MaTAR25: a long non-coding RNA involved in breast cancer progression. Molecular and Cellular Oncology, 8 (2). p. 1882286. ISSN 2372-3556

Yu, Allen, Berasain, Carmen, Bhatia, Sonam, Rivera, Keith, Liu, Bodu, Rigo, Frank, Pappin, Darryl, Spector, David (2021) PHAROH lncRNA regulates c-Myc translation in hepatocellular carcinoma via sequestering TIAR. bioRxiv. (Submitted)

Moravec, Jiří, Lanfear, Rob, Spector, David, Diermeier, Sarah, Gavryushkin, Alex (2021) Testing for phylogenetic signal in single-cell RNA-seq data. (Submitted)

Chang, K. C., Diermeier, S. D., Yu, A. T., Brine, L. D., Russo, S., Bhatia, S., Alsudani, H., Kostroff, K., Bhuiya, T., Brogi, E., Pappin, D. J., Bennett, C. F., Rigo, F., Spector, D. L. (December 2020) MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression. Nat Commun, 11 (1). p. 6438. ISSN 2041-1723

Aganezov, S., Goodwin, S., Sherman, R. M., Sedlazeck, F. J., Arun, G., Bhatia, S., Lee, I., Kirsche, M., Wappel, R., Kramer, M., Kostroff, K., Spector, D. L., Timp, W., McCombie, W. R., Schatz, M. C. (September 2020) Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing. Genome Res, 30 (9). pp. 1258-1273. ISSN 1088-9051 (Print)1088-9051

Sun, Lijuan, Kees, Tim, Almeida, Ana Santos, Liu, Bodu, He, Xue-Yan, Ng, David, Spector, David, McNeish, Iain A, Gimotty, Phyllis, Adams, Sylvia, Egeblad, Mikala (July 2020) Activating a collaborative innate-adaptive immune response to control breast and ovarian cancer metastasis. BioRxiv. (Unpublished)

Arun, G., Aggarwal, D., Spector, D. L. (June 2020) MALAT1 Long Non-Coding RNA: Functional Implications. Noncoding RNA, 6 (2). E22.

Chang, K. C., Diermeier, S. D., Yu, A. T., Brine, L. D., Russo, S., Bhatia, S., Alsudani, H., Kostroff, K., Bhuiya, T., Brogi, E., Bennett, C. F., Rigo, F., Spector, D. L. (February 2020) MaTAR25 LncRNA Regulates the Tensin1 Gene to Impact Breast Cancer Progression. BioRxiv. (Unpublished)

Arun, G., Spector, D. L. (March 2019) MALAT1 Long Non-Coding RNA and Breast Cancer. RNA Biol, 16 (6). pp. 860-863. ISSN 1547-6286

Abulwerdi, F. A., Xu, W., Ageeli, A. A., Yonkunas, M. J., Arun, G., Nam, H., Schneekloth, J. S., Dayie, T. K., Spector, D., Baird, N., Le Grice, S. F. J. (February 2019) Selective Small-Molecule Targeting of a Triple Helix Encoded by the Long Noncoding RNA, MALAT1. ACS Chemical Biology, 14 (2). pp. 223-235. ISSN 15548929 (ISSN) (Public Dataset)

Huang, Y. H., Klingbeil, O., He, X. Y., Wu, X. S., Arun, G., Lu, B., Somerville, T. D. D., Milazzo, J. P., Wilkinson, J. E., Demerdash, O. E., Spector, D. L., Egeblad, M., Shi, J., Vakoc, C. R. (July 2018) POU2F3 is a master regulator of a tuft cell-like variant of small cell lung cancer. Genes Dev, 32 (13-14). pp. 915-928. ISSN 0890-9369

Arun, G., Diermeier, S. D., Spector, D. L. (February 2018) Therapeutic Targeting of Long Non-Coding RNAs in Cancer. Trends Mol Med, 24 (3). pp. 257-277. ISSN 1471-4914

Diermeier, S. D., Spector, D. L. (August 2017) Antisense Oligonucleotide-mediated Knockdown in Mammary Tumor Organoids. Bio Protoc, 7 (16). ISSN 2331-8325 (Print)2331-8325

Li, M. A., Amaral, P. P., Cheung, P., Bergmann, J. H., Kinoshita, M., Kalkan, T., Ralser, M., Robson, S., Meyenn, F. V., Paramor, M., Yang, F., Chen, C., Nichols, J., Spector, D. L., Kouzarides, T., He, L., Smith, A. (August 2017) A lncRNA fine tunes the dynamics of a cell state transition involving Lin28, let-7 and de novo DNA methylation. Elife, 6. ISSN 2050-084x

Spector, D. L. (April 2017) The Role of Long Non-Coding RNAs in Nuclear Organization and Disease. Faseb Journal, 31 (Supple). Meeting Abstract 255.2. ISSN 0892-66381530-6860

Zhang, Bin, Mao, Yuntao S., Diermeier, Sarah D., Novikova, Irina V., Nawrocki, Eric P., Jones, Tom A., Lazar, Zsolt, Tung, Chang-Shung, Luo, Weijun, Eddy, Sean R., Sanbonmatsu, Karissa Y., Spector, David L. (2017) Identification and Characterization of a Class of MALAT1-like Genomic Loci. Cell Reports, 19 (8). pp. 1723-1738. ISSN 2211-1247 (Public Dataset)

Yu, A. T., Bergmann, J. H., Berasain, C., Rigo, F., Spector, D. L. (December 2016) Probing the Role of a Highly Expressed Long Non-Coding RNA in Hepatocellular Carcinoma. Molecular Biology of the Cell, 27. Abstract P343. ISSN 1059-15241939-4586

Diermeier, Sarah D, Chang, Kung-Chi, Freier, Susan M, Song, Junyan, El Demerdash, Osama, Krasnitz, Alexander, Rigo, Frank, Bennett, C.  Frank, Spector, David L (September 2016) Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration. Cell Reports, 17 (1). pp. 261-274. ISSN 2211-1247 (Public Dataset)

Kumaran, R. I., Li, J. J., Dynan, W. S., Porteus, M. H., Spector, D. L. (May 2016) Analysis of DNA Repair Pathway Choice Upon Induction of Double-Strand Breaks by Engineered Nuclease. Molecular Therapy, 24 (Supple). S225-S225. ISSN 1525-0016

Arun, G., Diermeier, S., Akerman, M., Chang, K. C., Wilkinson, J. E., Hearn, S., Kim, Y., MacLeod, A. R., Krainer, A. R., Norton, L., Brogi, E., Egeblad, M., Spector, D. L. (March 2016) Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss. Cancer Research, 76 (Supple). ISSN 0008-5472

Diermeier, S. D., Chang, K. C., Freier, S. M., Rigo, F., Bennett, C. F., Spector, D. L. (March 2016) Long noncoding RNAs as targets of mammary tumor cell proliferation and migration. Cancer Research, 76. ISSN 0008-5472

Arun, G., Diermeier, S., Akerman, M., Chang, K. C., Wilkinson, J. E., Hearn, S., Kim, Y., MacLeod, A. R., Krainer, A. R., Norton, L., Brogi, E., Egeblad, M., Spector, D. L. (January 2016) Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes Dev, 30 (1). pp. 34-51. ISSN 1549-5477 (Electronic)0890-9369 (Linking) (Public Dataset)

Jordan, Shawn (2016) David Spector: Coordinating gene expression in space and time. The Journal of Cell Biology, 214 (7). pp. 786-787.

Zepeda-Mendoza, C. J., Mukhopadhyay, S., Wong, E. S., Harder, N., Splinter, E., de Wit, E., Eckersley-Maslin, M. A., Ried, T., Eils, R., Rohr, K., Mills, A., de Laat, W., Flicek, P., Sengupta, A. M., Spector, D. L. (November 2015) Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2. BMC Genomics, 16 (1). p. 982. ISSN 1471-2164 (Electronic)1471-2164 (Linking)

Bergmann, J. H., Li, J., Eckersley-Maslin, M. A., Rigo, F., Freier, S. M., Spector, D. L. (September 2015) Regulation of the ESC transcriptome by nuclear long non-coding RNAs. Genome Res, 25 (9). pp. 1336-1346. ISSN 1549-5469 (Electronic)1088-9051 (Linking)

Hogan, Megan S, Parfitt, David-Emlyn, Zepeda-Mendoza, Cinthya J, Shen, Michael M, Spector, David L (March 2015) Transient Pairing of Homologous Oct4 Alleles Accompanies the Onset of Embryonic Stem Cell Differentiation. Cell Stem Cell, 16 (3). pp. 275-288. ISSN 1934-5909

Tektonidis, Marco, Kim, Il-Han, Chen, Yi-Chun M., Eils, Roland, Spector, David L., Rohr, Karl (January 2015) Non-Rigid Multi-Frame registration of cell nuclei in live cell fluorescence microscopy image data. Medical Image Analysis, 19 (1). pp. 1-14. ISSN 1361-8415

Eckersley-Maslin, M. A., Spector, D. L. (June 2014) Random monoallelic expression: Regulating gene expression one allele at a time. Trends in Genetics, 30 (6). pp. 237-244. ISSN 13624555

Bell, R. D., Long, X., Lin, M., Bergmann, J. H., Nanda, V., Cowan, S. L., Zhou, Q., Han, Y., Spector, D. L., Zheng, D., Miano, J. M. (February 2014) Identification and Initial Functional Characterization of a Human Vascular Cell-Enriched Long Noncoding RNA. Arteriosclerosis, thrombosis, and vascular biology, 34 (6). pp. 1249-1259. ISSN 1079-5642

Eckersley-Maslin, M. A., Thybert, D., Bergmann, J. H., Marioni, J. C., Flicek, P., Spector, D. L. (February 2014) Random Monoallelic Gene Expression Increases upon Embryonic Stem Cell Differentiation. Developmental Cell, 28 (4). pp. 351-65. ISSN 1534-5807

Bergmann, Jan H., Spector, David L. (February 2014) Long non-coding RNAs: modulators of nuclear structure and function. Current Opinion in Cell Biology, 26. pp. 10-18. ISSN 0955-0674

Shi, J., Whyte, W. A., Zepeda-Mendoza, C. J., Milazzo, J. P., Shen, C., Roe, J. S., Minder, J. L., Mercan, F., Wang, E., Eckersley-Maslin, M. A., Campbell, A. E., Kawaoka, S., Shareef, S., Zhu, Z., Kendall, J., Muhar, M., Haslinger, C., Yu, M., Roeder, R. G., Wigler, M. A., Blobel, G. A., Zuber, J., Spector, D. L., Young, R. A., Vakoc, C. R. (November 2013) Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes and Development, 27 (24). pp. 264-273. ISSN 08909369 (ISSN)

Dowen, Jill M., Bilodeau, Steve, Orlando, David A., Hübner, Michael R., Abraham, Brian J., Spector, David L., Young, Richard A. (October 2013) Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements. Stem Cell Reports, 1 (5). pp. 371-378. ISSN 2213-6711

Chen, Z., Jaafar, L., Agyekum, D. G., Xiao, H., Wade, M. F., Kumaran, R. I., Spector, D. L., Bao, G., Porteus, M. H., Dynan, W. S., Meiler, S. E. (August 2013) Receptor-mediated delivery of engineered nucleases for genome modification. Nucleic Acids Research, 41 (19). ISSN 03051048 (ISSN)

Bodnar, M. S., Spector, D. L. (June 2013) Chromatin Meets Its Organizers. Cell, 153 (6). pp. 1187-1189. ISSN 0092-8674

Hubner, M. R., Eckersley-Maslin, M. A., Spector, D. L. (April 2013) Chromatin organization and transcriptional regulation. Current Opinion in Genetics & Development, 23 (2). pp. 89-95. ISSN 0959-437X

Gutschner, T., Hammerle, M., Eissmann, M., Hsu, J., Kim, Y., Hung, G. N., Revenko, A., Arun, G., Stentrup, M., Gross, M., Zornig, M., MacLeod, A. R., Spector, D. L., Diederichs, S. (April 2013) The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model. Cancer Research, 73 (8 (Sup). p. 1121. ISSN 0008-5472

Gutschner, T., Hammerle, M., Eißmann, M., Hsu, J., Kim, Y., Hung, G., Revenko, A., Arun, G., Stentrup, M., Groß, M., Zörnig, M., MacLeod, A. R., Spector, D. L., Diederichs, S. (February 2013) The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Research, 73 (3). pp. 1180-1189. ISSN 00085472 (ISSN)

Eckersley-Maslin, M. A., Bergmann, J. H., Lazar, Z., Spector, D. L. (January 2013) Lamin A/C is Expressed in Pluripotent Mouse Embryonic Stem Cells. Nucleus, 4 (1). pp. 53-60. ISSN 1949-1042 (Electronic)1949-1042 (Linking)

Zhang, B., Arun, G., Mao, Y. S., Lazar, Z., Hung, G., Bhattacharjee, G., Xiao, X., Booth, C. J., Wu, J., Zhang, C., Spector, D. L. (2012) The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult. Cell Reports, 2 (1). pp. 111-123. ISSN 2211-1247

Meiler, S. E., Dynan, W. S., Porteus, M., Spector, D. L., Bao, G., Chen, Z., Pandey, J., Goyal, D., Kumaran, R. I., Wade, M., Agyekum, D. G. (November 2011) A Biological Delivery Platform for Zinc Finger Nucleases Using Transferrin-Mediated Endocytosis. Blood, 118 (21). p. 1071. ISSN 0006-4971

Zhao, R., Nakamura, T., Fu, Y., Lazar, Z., Spector, D. L. (November 2011) Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation. Nature Cell Biology, 13 (11). 1295-1304 . ISSN 1465-7392

Spector, D. L., Lamond, A. I. (February 2011) Nuclear Speckles. Cold Spring Harbor Perspectives in Biology, 3 (2). ISSN 1943-0264 (Electronic)

Harder, N., Bodnar, M., Eils, R., Spector, D. L., Rohr, K. (2011) 3D segmentation and quantification of mouse embryonic stem cells in fluorescence microscopy images. 2011 IEEE International Symposium on Biomedical Imaging: From Nano to Macro. pp. 216-219.

Mao, Y. S., Zhang, B., Spector, D. L. (2011) Biogenesis and function of nuclear bodies. Trends in Genetics, 27. pp. 295-306. ISSN 0168-9525

Mao, Y. S., Sunwoo, H., Zhang, B., Spector, D. L. (2011) Direct visualization of the co-transcriptional assembly of a nuclear body by noncoding RNAs. Nature Cell Biology, 13 (1). pp. 95-9101. ISSN 1465-7392

Shi, L., Wang, J., Hong, F., Spector, D. L., Fang, Y. (2011) Four amino acids guide the assembly or disassembly of Arabidopsis histone H3.3-containing nucleosomes. Proceedings of the National Academy of Sciences of the United States of America, 108 (26). pp. 10574-10578. ISSN 0027-8424

Spector, David L. (2011) Immunofluorescence localization of nuclear proteins. Cold Spring Harbor Protocols, 2011 (10). pp. 1276-1280. ISSN 1559-6095

Kim, Il-Han, Chen, Yi-Chun M., Spector, David L., Eils, Roland, Rohr, Karl (2011) Nonrigid registration of 2-D and 3-D dynamic cell nuclei images for improved classification of subcellular particle motion. IEEE Trans Image Process., 20 (4). pp. 1011-1022. ISSN 1941-0042

Prasanth, K. V. , Camiolo, M., Chan, G., Tripathi, V., Denis, L., Nakamura, T., Hubner, M., Spector, D. L. (December 2010) Nuclear Organization and Dynamics of 7SK RNA in Regulating Gene Expression. Molecular Biology of the Cell, 21 (23). pp. 4184-4196. ISSN 1059-1524

Oda, H., Hübner, M. R. , Beck, D. B., Vermeulen, M., Hurwitz, J., Spector, D. L., Reinberg, D. (November 2010) Regulation of the Histone H4 Monomethylase PR-Set7 by CRL4 (Cdt2)-Mediated PCNA-Dependent Degradation during DNA Damage. Molecular Cell, 40 (3). pp. 364-376.

Spector, D. L., Goldman, R. D. (November 2010) Transfection of mammalian cells with fluorescent protein fusions. Cold Spring Harbor Protocols, 2010 (11). ISSN 1559-6095

Ben-Ari, Y., Brody, Y., Kinor, N., Mor, A., Tsukamoto, T., Spector, D. L., Singer, R. H., Shav-Tal, Y. (May 2010) The life of an mRNA in space and time. Journal of Cell Science, 123 (10). pp. 1761-1774. ISSN 0021-9533

Hüber, M. R., Spector, D. L. (April 2010) Chromatin dynamics. Annual Review of Biophysics, 39. pp. 471-489.

Fang, Y., Spector, D. L. (2010) BiFC imaging assay for plant protein-protein interactions. Cold Spring Harbor Protocols, 2010 (2). ISSN 1559-6095

Spector, D. L., Goldman, R. D. (2010) Constructing and expressing fluorescent protein fusions. Cold Spring Harbor Protocols, 2010 (11). ISSN 1559-6095

Fang, Y., Spector, D. L. (2010) Four-dimensional imaging of plant cells during the cell cycle. Cold Spring Harbor Protocols, 2010 (2). ISSN 1559-6095

Fang, Y., Spector, D. L. (2010) Live cell imaging of plants. Cold Spring Harbor Protocols, 2010 (2). ISSN 1559-6095

Hubner, M. R., Spector, D. L. (2010) Role of H3K27 Demethylases Jmjd3 and UTX in Transcriptional Regulation. Cold Spring Harbor Symposia on Quantitative Biology, 75. pp. 43-49. ISSN 00917451 (ISSN)

Bernard, D., Prasanth, K. V. , Tripathi, V., Colasse, S., Nakamura, T., Xuan, Z., Zhang, M. Q. , Sedel, F., Jourdren, L., Coulpier, F., Triller, A., Spector, D. L., Bessis, A. (2010) A long nuclear-retained non-coding RNA regulates synaptogenesis by modulating gene expression. EMBO Journal, 29 (18). pp. 3082-3093.

Wilusz, J. E., Spector, D. L. (2010) An unexpected ending: Noncanonical 3′ end processing mechanisms. RNA, 16 (2). pp. 259-266. ISSN 13558382 (ISSN)

Wilusz, J. E., Sunwoo, H., Spector, D. L. (July 2009) Long noncoding RNAs: functional surprises from the RNA world. Genes & Development, 23 (13). pp. 1494-1504. ISSN 0890-9369

Zhao, R., Bodnar, M. S., Spector, D. L. (April 2009) Nuclear neighborhoods and gene expression. Current Opinion in Genetics & Development, 19 (2). pp. 172-179. ISSN 0959-437X

Sunwoo, H., Dinger, M. E., Wilusz, J. E., Amaral, P. P., Mattick, J. S., Spector, D. L. (March 2009) MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Research, 19 (3). pp. 347-359. ISSN 10889051 (ISSN)

Dimitrova, N., Chen, Y. C. M., Spector, D. L., de Lange, T. (November 2008) 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature, 456 (7221). pp. 524-528.

Wilusz, J. E., Freier, S. M., Spector, D. L. (November 2008) 3' End Processing of a Long Nuclear-Retained Noncoding RNA Yields a tRNA-like Cytoplasmic RNA. Cell, 135 (5). pp. 919-932. ISSN 0092-8674

Chen, Y. C. M., Kappel, C., Beaudouin, J., Eils, R., Spector, D. L. (July 2008) Live Cell Dynamics of PML Nuclear Bodies upon Entry into and Exit from Mitosis. Molecular Biology of the Cell, 19 (7). pp. 3147-3162. ISSN 1059-1524

Kumaran, R. I., Thakar, R., Spector, D. L. (2008) Chromatin dynamics and gene positioning. Cell, 132 (6). pp. 929-934. ISSN 1097-4172 (Electronic) 0092-8674 (Linking)

Rosin, F. M., Watanabe, N., Cacas, Jean-Luc, Kato, N., Arroyo, J. M., Fang, Y., May, B., Vaughn, M., Simorowski, J., Ramu, U., McCombie, R., Spector, D. L., Martienssen, R. A., Lam, E. (2008) Genome-wide transposon tagging reveals location-dependent effects on transcription and chromatin organization in Arabidopsis. Plant Journal, 55 (3). pp. 514-525. ISSN 0960-7412

Kumaran, R. I., Spector, D. L. (2008) A genetic locus targeted to the nuclear periphery in living cells maintains its transcriptional competence. Journal of Cell Biology, 180. pp. 51-65. ISSN 0021-9525

Fang, Y., Spector, D. L. (May 2007) Identification of Nuclear Dicing Bodies Containing Proteins for MicroRNA Biogenesis in Living Arabidopsis Plants. Current Biology, 17 (9). pp. 818-823. ISSN 0960-9822 (Print)

Spector, D. L. (April 2007) Nuclear retained rnas regulating gene expression. Faseb Journal, 21 (5). A97. ISSN 0892-6638

Prasanth, K. V. , Spector, D. L. (2007) Eukaryotic regulatory RNAs: an answer to the 'genome complexity' conundrum. Genes & Development, 21 (1). pp. 11-42. ISSN 0890-9369

Lee, H., Quinn, J. C., Prasanth, K. V. , Swiss, V. A., Economides, K. D., Camacho, M. M., Spector, D. L., Abate-Shen, C. (December 2006) PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein. Genes and Development, 20 (7). pp. 784-794. ISSN 08909369

Spector, D. L. (December 2006) SnapShot: Cellular Bodies. Cell, 127 (5). p. 1070.

Politz, J. C. R., Tuft, R. A., Prasanth, K. V. , Baudendistel, N., Fogarty, K. E., Lifshitz, L. M., Langowski, J., Spector, D. L., Pederson, T. (March 2006) Rapid, diffusional shuttling of poly(A) RNA between nuclear speckles and the nucleoplasm. Molecular Biology of the Cell, 17 (3). pp. 1239-1249. ISSN 10591524

Spector, D. L., Goldman, R. D. (2006) Constructing and Expressing GFP Fusion Proteins. Cold Spring Harbor Protocols, 2006 (7). ISSN 1940-3402 (Print) 1559-6095 (Electronic)

Fang, Y., Spector, D. L. (December 2005) Centromere positioning and dynamics in living Arabidopsis plants. Mol Biol Cell, 16 (12). pp. 5710-8. ISSN 1059-1524 (Print)

May, B. P., Lippman, Z. B., Fang, Y., Spector, D. L., Martienssen, R. A. (December 2005) Differential regulation of strand-specific transcripts from Arabidopsis centromeric satellite repeats. PLoS Genet, 1 (6). e79. ISSN 1553-7404 (Electronic)

Zilfou, J. T., Spector, M. S., Lowe, S. W. (November 2005) Slugging it out: fine tuning the p53-PUMA death connection. Cell, 123 (4). pp. 545-8. ISSN 0092-8674 (Print)

Prasanth, K. V. , Prasanth, S. G., Xuan, Z. Y., Hearn, S., Freier, S. M., Bennett, C. F., Zhang, M. Q., Spector, D. L. (October 2005) Regulating gene expression through RNA nuclear retention. Cell, 123 (2). pp. 249-263. ISSN 0092-8674

Spector, D. L. (March 2005) Nuclear dynamics and gene expression. Faseb Journal, 19 (4). A792-A792. ISSN 0892-6638

Bubulya, P. A., Prasanth, K. V. , Deerinck, T. J., Gerlich, D., Beaudouin, J., Ellisman, M. H. , Ellenberg, J., Spector, D. L. (October 2004) Hypophosphorylated SR splicing factors transiently localize around active nucleolar organizing regions in telophase daughter nuclei. J Cell Biol, 167 (1). pp. 51-63. ISSN 0021-9525 (Print)

Spector, D. L. (September 2004) Stopping for FISH and chips along the chromatin fiber superhighway. Mol Cell, 15 (6). pp. 844-6. ISSN 1097-2765 (Print)

Saitoh, N., Spahr, C. S., Patterson, S. D., Bubulya, P., Neuwald, A. F., Spector, D. L. (August 2004) Proteomic analysis of interchromatin granule clusters. Mol Biol Cell, 15 (8). pp. 3876-90. ISSN 1059-1524 (Print)

Prasanth, S. G., Prasanth, K. V. , Siddiqui, K., Spector, D. L., Stillman, B. (July 2004) Human Orc2 localizes to centrosomes, centromeres and heterochromatin during chromosome inheritance. EMBO J, 23 (13). pp. 2651-63. ISSN 0261-4189 (Print)

Ono, T., Fang, Y., Spector, D. L., Hirano, T. (July 2004) Spatial and temporal regulation of Condensins I and II in mitotic chromosome assembly in human cells. Mol Biol Cell, 15 (7). pp. 3296-308.

Shav-Tal, Y., Darzacq, X., Shenoy, S. M., Fusco, D., Janicki, S. M., Spector, D. L., Singer, R. H. (June 2004) Dynamics of single mRNPs in nuclei of living cells. Science, 304 (5678). pp. 1797-1800. ISSN 0036-8075

Izaurralde, Elisa , Spector, David L. (June 2004) Nucleus and gene expression: The interplay of transcriptional mechanisms that regulate gene and post-transcriptional expression. Current Opinion in Cell Biology, 16 (3). pp. 219-222. ISSN 0955-0674

Fang, Y., Hearn, S., Spector, D. L. (June 2004) Tissue-specific expression and dynamic organization of SR splicing factors in Arabidopsis. Mol Biol Cell, 15 (6). pp. 2664-73. ISSN 1059-1524 (Print)

Bubulya, P. A., Spector, D. L. (May 2004) "On the move"ments of nuclear components in living cells. Exp Cell Res, 296 (1). pp. 4-11. ISSN 0014-4827 (Print)

Spector, D. L. (May 2004) Visualizing the central dogma in living cells: DNA -> RNA -> protein. Faseb Journal, 18 (8). C312-C312. ISSN 0892-6638

Janicki, S. M., Tsukamoto, T., Salghetti, S. E., Tansey, W. P., Sachidanandam, R., Prasanth, K. V. , Ried, T., Shav-Tal, Y., Bertrand, E., Singer, R. H., Spector, D. L. (March 2004) From silencing to gene expression: real-time analysis in single cells. Cell, 116 (5). pp. 683-98. ISSN 0092-8674 (Print)

Narita, M., Nunez, S., Heard, E., Narita, M., Lin, A. W., Hearn, S. A., Spector, D. L., Hannon, G. J., Lowe, S. W. (June 2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell, 113 (6). pp. 703-716. ISSN 0092-8674

Janicki, S. M., Spector, D. L. (2003) Nuclear choreography: interpretations from living cells. Current Opinion in Cell Biology, 15 (2). pp. 149-157. ISSN 0955-0674

Lamond, A. I., Spector, D. L. (2003) Nuclear speckles: a model for nuclear organelles. Nature Reviews Molecular Cell Biology, 4. pp. 605-612. ISSN 1471-0072

Prasanth, K. V. , Sacco-Bubulya, P. A., Prasanth, S. G., Spector, D. L. (2003) Sequential entry of components of the gene expression machinery into daughter nuclei. Molecular Biology of the Cell, 14 (3). pp. 1043-1057. ISSN 1059-1524

Spector, D. L. (2003) The dynamics of chromosome organization and gene regulation. Annual Review of Biochemistry, 72. pp. 573-608. ISSN 0066-4154

Spector, D. L., Gasser, S. M. (2003) A molecular dissection of nuclear function. Conference on the dynamic nucleus: questions and implications. Embo Reports, 4. pp. 18-23. ISSN 1469-221X

Janicki, S. M., Tsukamoto, T., Spector, D. L. (November 2002) Live-cell visualization of the dynamics of chromatin associated factors during the transition from a transcriptionally inactive to an active state. Molecular Biology of the Cell, 13. 238A-238A. ISSN 1059-1524

Sacco-Bubulya, P. A., Prasanth, K. V. , Spector, D. L. (November 2002) Pre-mRNA splicing factors initially localize around active NORs upon entry into daughter nuclei. Molecular Biology of the Cell, 13. 106A-106A. ISSN 1059-1524

Spector, D. L., Tsukamota, T., Bertrand, E., Fusco, D., Singer, R., Janicki, S. M. (November 2002) Visualizing the dynamics of gene expression in living cells. Molecular Biology of the Cell, 13. 2A-2A. ISSN 1059-1524

Boggs, B. A., Cheung, P., Heard, E., Spector, D. L., Chinault, A. C., Allis, C. D. (January 2002) Differentially methylated forms of histone H3 show unique association patterns with inactive human X chromosomes. Nature Genetics, 30 (1). pp. 73-76. ISSN 1061-4036

Sacco-Bubulya, P. A., Spector, D. L. (2002) Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing. Journal of Cell Biology, 156 (3). pp. 425-436. ISSN 0021-9525

Muratani, M., Gerlich, D., Janicki, S. M., Gebhard, M., Eils, R., Spector, D. L. (2002) Metabolic-energy-dependent movement of PML bodies within the mammalian cell nucleus. Nature Cell Biology, 4. pp. 106-110. ISSN 1465-7392

Sacco-Bubulya, P. A., Spector, D. L. (November 2001) Interchromatin granule clusters are essential for coordinating transcription and pre-mRNA splicing. Molecular Biology of the Cell, 12. 103A-103A. ISSN 1059-1524

Kannanganattu, P. K. V., Sacco-Bubulya, P. A., Spector, D. L. (November 2001) Sequential entry of transcription/RNA processing factors into post-mitotic daughter nuclei. Molecular Biology of the Cell, 12. 101A-101A. ISSN 1059-1524

Heard, E., Rougeulle, C., Arnaud, D., Avner, P., Allis, C. D., Spector, D. L. (2001) Methylation of histone H3 at Lys-9 is an early mark on the X chromosome during X inactivation. Cell, 107 (6). pp. 727-738. ISSN 0092-8674

Spector, D. L. (2001) Nuclear domains. Journal of Cell Science, 114. pp. 2891-2893. ISSN 0021-9533

Saitoh, N., Patterson, S. D., Spahr, C. S., Howard, T., Neuwald, A. F., Spector, D. L. (December 2000) Development of an in vitro system to recapitulate interchromatin granule cluster dynamics. Molecular Biology of the Cell, 11. 19A-19A. ISSN 1059-1524

Sacco-Bubulya, P. A., Howard, T. A., Spector, D. L. (December 2000) Probing the organization and function of interchromatin granule clusters. Molecular Biology of the Cell, 11. 18A-19A. ISSN 1059-1524

Tsukamoto, T., Hashiguchi, N., Janicki, S. M., Tumbar, T., Belmont, A. S., Spector, D. L. (December 2000) Visualization of gene activity in living cells. Nature Cell Biology, 2. pp. 871-878. ISSN 1465-7392

Mintz, P. J., Spector, D. L. (2000) Compartmentalization of RNA processing factors within nuclear speckles. Journal of Structural Biology, 129 (2-3). pp. 241-251. ISSN 1047-8477

Raska, I., Spector, D. L. (2000) An "Eclipse" over the cell nucleus at the turn of the century. Journal of Structural Biology, 129 (2-3). p. 101. ISSN 1095-8657

Lorenz, P., Misteli, T., Baker, B. F., Bennett, C. F., Spector, D. L. (2000) Nucleocytoplasmic shuttling: a novel in vivo property of antisense phosphorothioate oligodeoxynucleotides. Nucleic Acids Research, 28 (2). pp. 582-592. ISSN 03051048 (ISSN)

Eils, R., Gerlich, D., Tvarusko, W., Spector, D. L., Misteli, T. (2000) Quantitative imaging of pre-mRNA splicing factors in living cells. Molecular Biology of the Cell, 11 (2). pp. 413-418. ISSN 1059-1524

Spector, D. L., Misteli, T. (December 1999) 8 dynamics of gene expression. Journal of Histochemistry and Cytochemistry, 47 (12). 1644C-1644. ISSN 0022-1554

Tvarusko, W., Bentele, M., Misteli, Tom, Rudolf, R., Kaether, C., Spector, David L., Gerdes, H. H., Eils, R. (July 1999) Time-resolved analysis and visualization of dynamic processes in living cells. Proceedings of the National Academy of Sciences of the United States of America, 96 (14). pp. 7950-5. ISSN 0027-8424

Mintz, P. J., Patterson, S. D., Neuwald, A. F., Spahr, C. S., Spector, D. L. (1999) Purification and biochemical characterization of interchromatin granule clusters. Embo Journal, 18 (15). pp. 4308-4320. ISSN 0261-4189

Misteli, T., Spector, D. L. (1999) RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo. Molecular Cell, 3. pp. 697-705. ISSN 1097-2765

Lorenz, P., Baker, B. F., Bennett, C. F., Spector, D. L. (1998) Phosphorothioate antisense oligonucleotides induce the formation of nuclear bodies. Molecular Biology of the Cell, 9 (5). pp. 1007-1023. ISSN 1059-1524

Misteli, T., Cáceres, J. F., Clement, J. Q., Krainer, A. R., Wilkinson, M. F., Spector, D. L. (1998) Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. Journal of Cell Biology, 143 (2). pp. 297-307. ISSN 0021-9525

Misteli, T., Spector, D. L. (1998) The cellular organization of gene expression. Current Opinion in Cell Biology, 10. pp. 323-331. ISSN 0955-0674

Huang, S., Deerinck, T. J., Ellisman, M. H. , Spector, D. L. (1998) The perinucleolar compartment and transcription. Journal of Cell Biology, 143 (1). pp. 35-47. ISSN 0021-9525

Misteli, T., Cáceres, J. F., Krainer, A. R., Spector, D. L. (November 1997) The control of splicing factor recruitment to sites of transcription in-vivo. Molecular Biology of the Cell, 8. p. 597. ISSN 1059-1524

Cáceres, J. F., Misteli, T., Screaton, G. R., Spector, D. L., Krainer, A. R. (July 1997) Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity. Journal of Cell Biology, 138 (2). pp. 225-38. ISSN 0021-9525

Huang, S., Deerinck, T. J., Ellisman, M. H. , Spector, D. L. (June 1997) The dynamic organization of the perinucleolar compartment in the cell nucleus. Journal of Cell Biology, 137 (5). pp. 965-74. ISSN 0021-9525

Misteli, T., Spector, D. L. (1997) Applications of the green fluorescent protein in cell biology and biotechnology. Nature Biotechnology, 15 (10). pp. 961-964. ISSN 1546-1696 (Electronic) 1087-0156 (Linking)

Misteli, T., Spector, D. L. (1997) Protein phosphorylation and the nuclear organization of pre-mRNA splicing. Trends In Cell Biology, 7 (4). pp. 135-138. ISSN 0962-8924

Huang, S., Mayeda, A., Krainer, A. R., Spector, D. L. (1997) RCC1 and nuclear organization. Molecular Biology of the Cell, 8 (6). pp. 1143-1157. ISSN 1059-1524

Powell, R. D., Halsey, C. M., Spector, D. L., Kaurin, S. L., McCann, J., Hainfeld, J. F. (1997) A covalent fluorescent-gold immunoprobe: simultaneous detection of a pre-mRNA splicing factor by light and electron microscopy. Journal of Histochemistry and Cytochemistry, 45 (7). pp. 947-956. ISSN 0022-1554

Misteli, T., Cáceres, J. F., Spector, D. L. (1997) The dynamics of a pre-mRNA splicing factor in living cells. Nature, 387 (6632). pp. 523-527. ISSN 0028-0836

Henderson, S., Allsopp, R., Spector, D., Wang, S. S., Harley, C. (July 1996) In situ analysis of changes in telomere size during replicative aging and cell transformation. Journal of Cell Biology, 134 (1). pp. 1-12. ISSN 0021-9525 (Print)0021-9525

Huang, S., Spector, D. L. (1996) Dynamic organization of pre-mRNA splicing factors. Journal of Cellular Biochemistry, 62 (2). pp. 191-197. ISSN 0730-2312

Huang, S., Spector, D. L. (1996) Intron-dependent recruitment of pre-mRNA splicing factors to sites of transcription. Journal of Cell Biology, 133 (4). pp. 719-732. ISSN 0021-9525

Spector, D. L. (1996) Nuclear organization and gene expression. Experimental Cell Research, 229 (2). pp. 189-197. ISSN 0014-4827

Misteli, T., Spector, D. L. (1996) Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors. Molecular Biology of the Cell, 7. pp. 1559-1572. ISSN 1059-1524

Tani, T., Derby, R. J., Hiraoka, Y., Spector, D. L. (November 1995) Nucleolar accumulation of poly (A)+ RNA in heat-shocked yeast cells: implication of nucleolar involvement in mRNA transport. Molecular Biology of the Cell, 6 (11). pp. 1515-34. ISSN 1059-1524

Deerinck, T. J., Martone, M. E., Levram, V., Green, D. P. L., Tsien, R. Y., Spector, D. L., Huang, S., Ellisman, M. H. (August 1994) Fluorescence Photooxidation with Eosin - a Method for High-Resolution Immunolocalization and in-Situ Hybridization Detection for Light and Electron-Microscopy. Journal of Cell Biology, 126 (4). pp. 901-910. ISSN 0021-9525

Huang, S., Deerinck, T. J., Ellisman, M. H. , Spector, D. L. (August 1994) In vivo analysis of the stability and transport of nuclear poly(A)+ RNA. Journal of Cell Biology, 126 (4). pp. 877-99. ISSN 0021-9525

Spector, D. L., O'Keefe, R. T., Landon, S., Jimenez Garcia, L. F. (February 1994) Coordination of Transcription and Pre-Messenger-Rna Splicing within the Cell-Nucleus. Journal of Cellular Biochemistry, 56 (S18C). p. 85. ISSN 0730-2312

O'Keefe, R. T., Mayeda, A., Sadowski, C. L., Krainer, A. R., Spector, D. L. (1994) Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. Journal of Cell Biology, 124 (3). pp. 249-260. ISSN 0021-9525

Jimenez-Garcia, L. F., Segura-Valdez, M. L., Ochs, R. L., Rothblum, L. I., Hannan, R., Spector, D. L. (1994) Nucleologenesis: U3 snRNA-containing prenucleolar bodies move to sites of active pre-rRNA transcription after mitosis. Molecular Biology of the Cell, 5 (9). pp. 955-966. ISSN 1059-1524

Spector, D. L. (1994) RNA processing. Cycling splicing factors. Nature, 369 (6482). p. 604. ISSN 0028-0836

Spector, D. L., O'Keefe, R. T., Jimenez-Garcia, L. F. (1993) Dynamics of transcription and pre-mRNA splicing within the mammalian cell nucleus. Cold Spring Harbor Symposia on Quantitative Biology, 58. pp. 799-805. ISSN 00917451 (ISSN)

Jimenez-Garcia, L. F., Spector, D. L. (1993) In vivo evidence that transcription and splicing are coordinated by a recruiting mechanism. Cell, 73 (1). pp. 47-59. ISSN 0092-8674

Spector, D. L. (1993) Macromolecular domains within the cell nucleus. Annual Review of Cell and Developmental Biology, 9. pp. 265-315. ISSN 0743-4634

Spector, D. L. (1993) Nuclear organization of pre-mRNA processing. Current Opinion in Cell Biology, 5 (3). pp. 442-447. ISSN 0955-0674

Spector, D. L., Landon, S., O'Keefe, R. T. (1993) Organization of RNA polymerase II transcription and pre-mRNA splicing within the mammalian cell nucleus. Biochemical Society Transactions, 21 (4). pp. 918-920. ISSN 03005127 (ISSN)

Jimenez-Garcia, L. F., Green, S. R., Mathews, M. B., Spector, D. L. (1993) Organization of the double-stranded RNA-activated protein kinase DAI and virus-associated VA RNAI in adenovirus-2-infected HeLa cells. Journal of Cell Science, 106. pp. 11-22. ISSN 0021-9533 (ISSN)

Henderson, S. C., Spector, D. L. (September 1992) Nonrandom Arrangement of DNA-Sequences in Diploid Human-Cells. Molecular Biology of the Cell, 3 (Suppl). A137-A137. ISSN 1059-1524

Jimenez-Garcia, L. F., Spector, D. L. (September 1992) Reorganization of the Pre-Messenger-Rna Splicing Apparatus Upon Adenovirus Infection. Molecular Biology of the Cell, 3. A322-A322. ISSN 1059-1524

Spector, D. L., Lark, G., Huang, S. (1992) Differences in snRNP localization between transformed and nontransformed cells. Molecular Biology of the Cell, 3 (5). pp. 555-569. ISSN 1059-1524

O'Keefe, R. T., Henderson, S. C., Spector, D. L. (1992) Dynamic organization of DNA replication in mammalian cell nuclei: spatially and temporally defined replication of chromosome-specific alpha-satellite DNA sequences. Journal of Cell Biology, 116 (5). pp. 1095-1110. ISSN 0021-9525

Huang, S., Spector, D. L. (1992) U1 and U2 small nuclear RNAs are present in nuclear speckles. Proceedings of the National Academy of Sciences of the United States of America, 89 (1). pp. 305-308. ISSN 0027-8424

Huang, S., Spector, D. L. (1992) Will the real splicing sites please light up? Current Biology, 2 (4). pp. 188-190. ISSN 0960-9822

Sui, H., Spector, D. L. (December 1991) Nascent Pre-Messenger-Rna Transcripts Are Associated with Nuclear Regions Enriched in Splicing Factors. Genes & Development, 5 (12A). pp. 2288-2302. ISSN 0890-9369

Yu, I. J., Spector, D. L., Bae, Y.-S., Marshak, D. R. (September 1991) Immunocytochemical localization of casein kinase II during interphase and mitosis. J Cell Biol, 114 (6). pp. 1217-32. ISSN 0021-9525

Spector, D. L., Fu, X. D., Maniatis, T. (1991) Associations between distinct pre-mRNA splicing components and the cell nucleus. Embo Journal, 10 (11). pp. 3467-3481. ISSN 0261-4189

Powers, A. C., Efrat, S., Mojsov, S., Spector, D., Habener, J. F., Hanahan, D. (April 1990) Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor. Diabetes, 39 (4). pp. 406-14. ISSN 0012-1797 (Print)0012-1797

Spector, D. L. (1990) Higher order nuclear organization: three-dimensional distribution of small nuclear ribonucleoprotein particles. Proceedings of the National Academy of Sciences of the United States of America, 87 (1). pp. 147-151. ISSN 0027-8424

Conway, G. C., Krainer, A. R., Spector, D. L., Roberts, R. J. (December 1989) Multiple splicing factors are released from endogenous complexes during in vitro pre-mRNA splicing. Molecular & Cellular Biology, 9 (12). pp. 5273-80. ISSN 0270-7306

Spector, D. L., Sovak, M. (November 1989) 3-Dimensional Distribution of Small Nuclear Rnps and Reorganization of Small Nuclear Rnp-Enriched Nuclear Regions Upon Alterations in the Level of Transcription. Journal of Cell Biology, 109 (4 PART). 39A. ISSN 0021-95251540-8140

Chan, W. K., Chang, E., Carroll, D., Anderson, J. E., Marshak, D. R., Spector, D. L. (1989) The Structural Domains of the C-Myc Oncoprotein. Journal of Cell Biology, 109 (4 PART). 118A.

Efrat, S., Linde, S., Kofod, H., Spector, D., Delannoy, M., Grant, S., Hanahan, D., Baekkeskov, S. (December 1988) Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene. Proceedings of the National Academy of Sciences of the United States of America, 85 (23). pp. 9037-41. ISSN 0027-8424 (Print)0027-8424

White, E., Spector, D. L., Welch, W. (November 1988) Differential distribution of the adenovirus E1A proteins and colocalization of E1A with the 70-kilodalton cellular heat shock protein in infected cells. Journal of Virology, 62 (11). pp. 4153-66. ISSN 0022-538X

Scolnik, P. A., Hinton, P., Greenblatt, I. M., Giuliano, G., Delanoy, M. R., Spector, D. L., Pollock, D. (May 1987) Somatic instability of carotenoid biosynthesis in the tomato ghost mutant and its effect on plastid development. Planta, 171 (1). pp. 11-8. ISSN 0032-0935 (Print)0032-0935

Spector, D. L., Watt, R. A., Sullivan, N. F. (March 1987) The v- and c-myc oncogene proteins colocalize in situ with small nuclear ribonucleoprotein particles. Oncogene, 1 (1). pp. 5-12. ISSN 0950-9232

Sullivan, N. F., Spector, D. L., Watt, R. A. (1987) Association between the Myc-Oncogene Protein and Ribonucleoprotein-Particles. Journal of Cellular Biochemistry, 35 (S11C). p. 42. ISSN 0730-2312

Spector, D. L., White, E., Welch, W. J. (1987) Association of the Hsp70 Heat Shock Protein with Adenovirus E1a Proteins in Infected Cells. Journal of Cell Biology, 105 (4 PART). 108A.

Spector, D. L., Smith, H. C. (March 1986) Redistribution of U-snRNPs during mitosis. Experimental Cell Research, 163 (1). pp. 87-94.

Bennett, C. F., Spector, D. L., Yeoman, L. C. (February 1986) Nonhistone protein BA is a glutathione S-transferase localized to interchromatinic regions of the cell nucleus. Journal of Cell Biology, 102 (2). pp. 600-9. ISSN 0021-9525

Sullivan, N. F., Watt, R. A., Delannoy, M. R., Green, C. L., Spector, D. L. (1986) Colocalization of the Myc Oncogene Protein and Small Nuclear Ribonucleoprotein Particles. Cold Spring Harbor Symposia on Quantitative Biology, 51. pp. 943-948. ISSN 00917451 (ISSN)

Smith, H. C., Ochs, R. L., Fernandez, E. A., Spector, D. L. (1986) Macromolecular domains containing nuclear protein p107 and U-snRNP protein p28: further evidence for an in situ nuclear matrix. Molecular and Cellular Biology, 70 (2). pp. 151-168. ISSN 0270-7306

Reddy, R., Henning, D., Liu, M. H., Spector, D., Busch, H. (March 1985) Identification and characterization of a polyadenylated small RNA (s-poly A+ RNA) in dinoflagellates. Biochemical and Biophysical Research Communications, 127 (2). pp. 552-7. ISSN 0006-291X (Print)0006-291x

Smith, H. C., Spector, D. L., Woodcock, C. L., Ochs, R. L., Bhorjee, J. (1985) Alterations in chromatin conformation are accompanied by reorganization of nonchromatin domains that contain U-snRNP protein p28 and nuclear protein p107. Journal of Cell Biology, 101 (2). pp. 560-567. ISSN 0021-9525

Busch, H., Ochs, R. L., Smith, H. C., Spector, D. L. (1985) Nuclear Antigenic Structures. Scandinavian Journal of Rheumatology, 14 (S56). pp. 10-21. ISSN 0300-9742

Liu, M. H., Reddy, R., Henning, D., Spector, D., Busch, H. (February 1984) Primary and secondary structure of dinoflagellate U5 small nuclear RNA. Nucleic Acids Research, 12 (3). pp. 1529-42. ISSN 0305-1048 (Print)0305-1048

Spector, D. L. (1984) Colocalization of U1 and U2 small nuclear RNPs by immunocytochemistry. Biology of the Cell, 51 (1). pp. 109-112. ISSN 0248-4900

Spector, D. L., Schrier, W. H., Busch, H. (1984) Immunoelectron microscopic localization of snRNPs. Biology of the Cell, 49 (1). pp. 1-10. ISSN 0248-4900

Spector, D. L., Ochs, R. L., Busch, H. (1984) Silver staining, immunofluorescence, and immunoelectron microscopic localization of nucleolar phosphoproteins B23 and C23. Chromosoma, 90 (2). pp. 139-48. ISSN 0009-5915 (Print)

Spector, D. L., Triemer, R. E. (1981) Chromosome structure and mitosis in the dinoflagellates: an ultrastructural approach to an evolutionary problem. Biosystems, 14. pp. 289-298. ISSN 0303-2647

Spector, D. L., Vasconcelos, A. C., Triemer, R. E. (1981) DNA duplication and chromosome structure in the dinoflagellates. Protoplasm, 105 (3-4). pp. 185-194. ISSN 0033-183X

Book Section

Spector, D. L. (2007) Nuclear Organization and Gene Expression. In: From DNA to Proteins: The Multiple Levels of Regulation, The Biomedical & Life Sciences Collection. Henry Stewart Talks Ltd, London.

Prasanth, K. V. , Spector, D. L. (2005) The cell nucleus. In: Encyclopedia of life sciences. John Wiley & Sons, London ; New York. ISBN 0470016175

Spector, David L. (1997) Genes and transcripts in the interphase nucleus. In: Nuclear organization, chromatin structure and gene expression. Oxford University Press, Oxford, pp. 169-184. ISBN 0198549237

Huang, S., Spector, D. L. (1997) Pre-mRNA splicing: Nuclear organization of factors and substrates. In: Eukaryotic mRNA processing. Frontiers in Molecular Biology . IRL Press at Oxford University Press, pp. 37-67. ISBN 9780199634187

Spector, D. L., Lark, G., Sovak, M., Huang, S. (1991) Autoantibodies as probes for the molecular architecture of the nucleus. In: Proceedings, forty-ninth annual meeting, Electron Microscopy Society of America, San Jose, California, 4-9 August 1991. San Francisco Press, Inc., San Francisco, pp. 18-19.

Spector, D. L. (1990) The nucleus. In: Essential cell biology. Williams & Wilkins, Baltimore, pp. 39-73. ISBN 0683090518 9780683090512 0683094092 9780683094091

Spector, D. L. (1984) The Dinoflagellate Nucleus. In: Dinoflagellates. Elsevier Science, pp. 107-147. ISBN 9780323138130

Spector, D. L. (1984) Introduction to the Dinoflagellates. In: Dinoflagellates. Elsevier Science, pp. 1-15. ISBN 9780323138130

Spector, D. L. (1984) Unusual inclusions. In: Dinoflagellates. Elsevier Science, pp. 365-390. ISBN 9780323138130

Busch, H., Reddy, R., Henning, D., Spector, D. L., Epstein, P., Domae, N., Liu, M. H., Subrahmanyam, C. S., Schrier, W. H., Rothblum, L. (1982) Small nuclear RNPs and RNA processing. In: Gene Regulation: proceedings of the symposium on gene regulation held March 28-April 4, 1982, Keystone, Colorado. UCLA symposia on molecular and cellular biology, 26 . Academic Press, New York, pp. 167-187. ISBN 0125259603

Conference or Workshop Item

He, Xue-Yan, Gao, Yuan, Ng, David, Michalopoulou, Evdokia, George, Shanu, Adrover, Jose M, Sun, Lijuan, Albrengues, Jean, Dassler-Plenker, Juliane, Han, Xiao, Wan, Ledong, Wu, Xiaoli S, Shui, Longling S, Huang, Yu-Han, Liu, Bodu, Su, Chang, Spector, David L, Vakoc, Christopher R, VanAelst, Linda, Egeblad, Mikala (March 2024) Chronic stress causes metastasis via neutrophil-mediated changes to the microenvironment. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024, 2024 Apr 5-10, San Diego, CA.

Kumaran, RI, Li, J, Dynan, WS, Porteus, MH, Spector, DL (2015) Analysis of DNA repair pathway choice upon zinc finger nuclease induced double-strand breaks. In: UNSPECIFIED.

Grodzicker, T., Spector, D. L., Stewart, D., Stillman, B. (June 2010) Nuclear Organization & Function. In: Cold Spring Harbor Symposia on Quantitative Biology LXXV: Nuclear Organization and Function, June 2–June 7, 2010.

Book

Misteli, T., Spector, D. L., eds. (2011) The Nucleus. Cold Spring Harbor Perspectives in Biology, 3 (2). Cold Spring Harbor Laboratory Press. ISBN 1943-0264 (Electronic)

Goldman, R. D., Swedlow, J. R., Spector, D. L. (2010) Live Cell Imaging: A Laboratory Manual. Cold Spring Harbor Laboratory Press. ISBN 9780879698935

Spector, D. L., Godlman, R. D. (2006) Basic methods in microscopy : a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.. ISBN 0879697474

Goldman, R. D., Spector, D. L. (2005) Live cell imaging : a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York. ISBN 0879696834

Spector, David L., Goldman, Robert D. (2003) Essentials from cells: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N. Y.. ISBN 0879696672

Spector, D. L., Goldman, R. D., Leinwand, L. A. (1999) Cells: Basic Principles of Microscopy, a companion slide set. Cold Spring Harbor Laboratory Press. ISBN 9780879695224

Spector, D. L., Goldman, R. D., Leinwand, L. A. (1998) Cells: a laboratory manual. Cold Spring Harbor Laboratory Press. ISBN 9780879695224

Spector, David L., Goldman, Robert D., Leinwand, Leslie A. (1997) Cells: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York. ISBN 0879695226

Spector, D. L., Derby, R. J. (1990) Immunolocalization of nuclear antigens in cryofixed cells which have been prepared by molecular distillation drying or freeze-substitution. Electron Microscopy 1990: Proceedings of the XIIth International Congress for Electron Microscopy Held in Seattle, Washington, USA - 48th Annual Meeting of the Electron Microscopy Society of America and 25th Annual Meeting of the Microbeam Analysis Societ . San Francisco Press.

Spector, D. L. (1984) Dinoflagellates. Elsevier Science. ISBN 9780323138130

Video

Spector, D. L. (November 2012) Talk from David Spector at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Dataset

Zhang, B., Mao, Y. S., Diermeier, S. D., Novikova, I. V., Nawrocki, E. P., Jones, T. A., Lazar, Z., Tung, CS, Luo, W., Eddy, S. R., Sanbonmatsu, K. Y., Spector, D. L. (2017) Supplemental Dataset from Zhang, Bin, Mao, Yuntao S., Diermeier, Sarah D., Novikova, Irina V., Nawrocki, Eric P., Jones, Tom A., Lazar, Zsolt, Tung, Chang-Shung, Luo, Weijun, Eddy, Sean R., Sanbonmatsu, Karissa Y., Spector, David L. (2017) Identification and Characterization of a Class of MALAT1-like Genomic Loci. Cell Reports. [Dataset]