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Amit, Moran, Anastasaki, Corina, Dantzer, Robert, Demir, Ihsan Ekin, Deneen, Benjamin, Dixon, Karen O, Egeblad, Mikala, Gibson, Erin M, Hervey-Jumper, Shawn L, Hondermarck, Hubert, Magnon, Claire, Monje, Michelle, Na'ara, Shorook, Pan, Yuan, Repasky, Elizabeth A, Scheff, Nicole N, Sloan, Erica K, Talbot, Sebastien, Tracey, Kevin J, Trotman, Lloyd C, Valiente, Manuel, Van Aelst, Linda, Venkataramani, Varun, Venkatesh, Humsa S, Vermeer, Paola D, Winkler, Frank, Wong, Richard J, Gutmann, David H , Borniger, Jeremy C (2024) Next Directions in the Neuroscience of Cancers Arising outside the CNS. Cancer Discovery, 14(4) pp. 669-673.

He, Xue-Yan, Gao, Yuan, Ng, David, Michalopoulou, Evdokia, George, Shanu, Adrover, Jose M, Sun, Lijuan, Albrengues, Jean, Daßler-Plenker, Juliane, Han, Xiao, Wan, Ledong, Wu, Xiaoli Sky, Shui, Longling S, Huang, Yu-Han, Liu, Bodu, Su, Chang, Spector, David L, Vakoc, Christopher R, Van Aelst, Linda , Egeblad, Mikala (2024) Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment. Cancer Cell,

Ogawa, Yuki, Lim, Brian C, George, Shanu, Oses-Prieto, Juan A, Rasband, Joshua M, Eshed-Eisenbach, Yael, Hamdan, Hamdan, Nair, Supna, Boato, Francesco, Peles, Elior, Burlingame, Alma L, Van Aelst, Linda , Rasband, Matthew N (2023) Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments. Nature Communications, 14(1) pp. 6797.

de Ruiter Swain, Jed, Michalopoulou, Evdokia, Noch, Evan K, Lukey, Michael J , Van Aelst, Linda (2023) Metabolic partitioning in the brain and its hijacking by glioblastoma. Genes and Development, 37 pp. 681-702.

Ogawa, Yuki, Lim, Brian C, George, Shanu, Oses-Prieto, Juan A, Rasband, Joshua M, Eshed-Eisenbach, Yael, Nair, Supna, Boato, Francesco, Peles, Elior, Burlingame, Alma L, Van Aelst, Linda , Rasband, Matthew N (2023) Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments.

Gallo, Nicholas B, Berisha, Artan , Van Aelst, Linda (2022) Microglia regulate chandelier cell axo-axonic synaptogenesis. Proceedings of the National Academy of Sciences of USA, 119(11) pp. e2114476119.

Ge, Eva J, Bush, Ashley I, Casini, Angela, Cobine, Paul A, Cross, Justin R, DeNicola, Gina M, Dou, Q Ping, Franz, Katherine J, Gohil, Vishal M, Gupta, Sanjeev, Kaler, Stephen G, Lutsenko, Svetlana, Mittal, Vivek, Petris, Michael J, Polishchuk, Roman, Ralle, Martina, Schilsky, Michael L, Tonks, Nicholas K, Vahdat, Linda T, Van Aelst, Linda, Xi, Dan, Yuan, Peng, Brady, Donita C , Chang, Christopher J (2021) Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews Cancer,

Cheng, Derek K, Oni, Tobiloba E, Thalappillil, Jennifer S, Park, Youngkyu, Ting, Hsiu-Chi, Alagesan, Brinda, Prasad, Nadia V, Addison, Kenneth, Rivera, Keith D, Pappin, Darryl J, Van Aelst, Linda , Tuveson, David A (2021) Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer.. Proceedings of the National Academy of Sciences of USA, 118(21) pp. e2016904118-e2016904118.

Ango, Fabrice, Gallo, Nicholas Biron , Van Aelst, Linda (2021) Molecular mechanisms of axo-axonic innervation.. Current Opinion in Neurobiology, 69 pp. 105-112.

Wang, Minghui, Gallo, Nicholas B, Tai, Yilin, Li, Bo , Van Aelst, Linda (2021) Oligophrenin-1 moderates behavioral responses to stress by regulating parvalbumin interneuron activity in the medial prefrontal cortex. Neuron,

Fein, Miriam R, He, Xue-Yan, Almeida, Ana S, Bružas, Emilis, Pommier, Arnaud, Yan, Ran, Eberhardt, Anaïs, Fearon, Douglas T, Van Aelst, Linda, Wilkinson, John Erby, Dos Santos, Camila O , Egeblad, Mikala (2020) Cancer cell CCR2 orchestrates suppression of the adaptive immune response.. Journal of Experimental Medicine, 217(10)

Cheng, D. K., Oni, T. E., Park, Y., Thalappillil, J. S, Ting, H.-C., Alagesan, B., Prasad, N. V., Rivera, K. D., Pappin, D. J., Van Aelst, L. , Tuveson, D. A. (2020) Oncogenic KRAS engages an RSK1/NF1 complex in pancreatic cancer. BioRxiv,

Gallo, N. B., Paul, A. , Van Aelst, L. (2020) Shedding Light on Chandelier Cell Development, Connectivity, and Contribution to Neural Disorders. Trends in Neurosciences, 43(8) pp. 565-580. Cell Press.

He, X. Y., Ng, D., Van Aelst, L. , Egeblad, M. (2019) Stressing Out about Cancer Immunotherapy. Cancer Cell, 36(5) pp. 468-470.

Tai, Y., Gallo, N. B., Wang, M., Yu, J. R. , Van Aelst, L. (2019) Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron, 102(2) pp. 267-270. Cell Press.

Fein, Miriam, He, Xue-Yan, Almeida, Ana, Bružas, Emilis, Pommier, Arnaud, Yan, Ran, Eberhardt, Anaïs, Fearon, Douglas, Van Aelst, Linda, Wilkinson, John, dos Santos, Camila , Egeblad, Mikala (2018) Cancer cell CCR2 orchestrates suppression of the adaptive immune response. bioRxiv,

Nakamuta, S., Yang, Y. T., Wang, C. L., Gallo, N. B., Yu, J. R., Tai, Y. , Van Aelst, L. (2017) Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain. J Cell Biol, 216(12) pp. 4313-4330.

Krishnan, N., Krishnan, K., Connors, C. R., Choy, M. S., Page, R., Peti, W., Van Aelst, L., Shea, S. D. , Tonks, N. K. (2015) PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest, 125(8) pp. 3163-3177.

Penzo, M. A., Robert, V., Tucciarone, J., De Bundel, D., Wang, M., Van Aelst, L., Darvas, M., Parada, L. F., Palmiter, R. D., He, M., Huang, Z. J. , Li, B. (2015) The paraventricular thalamus controls a central amygdala fear circuit. Nature, 519(7544) pp. 455-459.

Yu, J. R., Tai, Y., Jin, Y., Hammell, M. C., Wilkinson, J. E., Roe, J. S., Vakoc, C. R. , Van Aelst, L. (2015) TGF-beta/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis. Genes Dev, 29(3) pp. 250-61.

Nakano-Kobayashi, A., Tai, Y., Nadif Kasri, N. , Van Aelst, L. (2014) The X-linked Mental Retardation Protein OPHN1 Interacts with Homer1b/c to Control Spine Endocytic Zone Positioning and Expression of Synaptic Potentiation. Journal of Neuroscience, 34(26) pp. 8665-71.

Murray, D. W., Didier, S., Chan, A., Paulino, V., Van Aelst, L., Ruggieri, R., Tran, N. L., Byrne, A. T. , Symons, M. (2014) Guanine nucleotide exchange factor Dock7 mediates HGF-induced glioblastoma cell invasion via Rac activation. British Journal of Cancer, 110(5) pp. 1307-1315.

Tai, Y., Janas, J. A., Wang, C. L. , Van Aelst, L. (2014) Regulation of Chandelier Cell Cartridge and Bouton Development via DOCK7-Mediated ErbB4 Activation. Cell Reports, 6(2) pp. 254-63.

Boettner, B. , Van Aelst, L. (2013) Introduction to the ECR special issue on the roles of small GTPases. Experimental Cell Research, 319(15) pp. 2309.

Anne, S. L., Govek, E. E., Ayrault, O., Kim, J. H., Zhu, X., Murphy, D. A., Van Aelst, L., Roussel, M. F. , Hatten, M. E. (2013) WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation. PLoS ONE, 8(11)

Berger, A. H., Chen, M., Morotti, A., Janas, J. A., Niki, M., Bronson, R. T., Taylor, B. S., Ladanyi, M., Van Aelst, L., Politi, K., Varmus, H. E. , Pandolfi, P. P. (2013) DOK2 inhibits EGFR-mutated lung adenocarcinoma. PLoS One, 8(11) pp. e79526.

Yang, Y. T., Wang, C. L. , Van Aelst, L. (2012) DOCK7 interacts with TACC3 to regulate interkinetic nuclear migration and cortical neurogenesis. Nature Neuroscience, 15(9) pp. 1201-10.

Zhang, X. C., Piccini, A., Myers, M. P., Van Aelst, L. , Tonks, N. K. (2012) Functional analysis of the protein phosphatase activity of PTEN. Biochem J, 444(3) pp. 457-64.

Hill, C. S. , Van Aelst, L. (2012) Signaling and gradients: what's going down?. Current Opinion in Cell Biology, 24(2) pp. 155-157.

Kang, H., Davis-Dusenbery, B. N., Nguyen, P. H., Lal, A., Lieberman, J., Van Aelst, L., Lagna, G. , Hata, A. (2012) Bone morphogenetic protein 4 promotes vascular smooth muscle contractility by activating microRNA-21 (miR-21), which down-regulates expression of family of dedicator of cytokinesis (DOCK) proteins. Journal of Biological Chemistry, 287(6) pp. 3976-3986.

Nadif Kasri, N., Nakano-Kobayashi, A. , Van Aelst, L. (2011) Rapid Synthesis of the X-Linked Mental Retardation Protein OPHN1 Mediates mGluR-Dependent LTD through Interaction with the Endocytic Machinery. Neuron, 72(2) pp. 300-315.

Govek, E. E., Hatten, M. E. , Van Aelst, L. (2011) The role of Rho GTPase proteins in CNS neuronal migration. Developmental Neurobiology, 71(6) pp. 528-553.

Janas, J. A. , Van Aelst, L. (2011) Oncogenic tyrosine kinases target Dok-1 for ubiquitin-mediated proteasomal degradation to promote cell transformation. Molecular and Cellular Biology, 31(13) pp. 2552-2565.

Svitkina, T., Lin, W. H., Webb, D. J., Yasuda, R., Wayman, G. A., Van Aelst, L. , Soderling, S. H. (2010) Regulation of the Postsynaptic Cytoskeleton: Roles in Development, Plasticity, and Disorders. J Neurosci, 30(45) pp. 14937-14942.

Van Aelst, L. , Caroni, P. (2010) Signaling mechanisms. Curr Opin Neurobiol, 20 pp. 1-3.

Boettner, B. , Van Aelst, L. (2009) Control of cell adhesion dynamics by Rap1 signaling. Curr Opin Cell Biol, 21(5) pp. 684-693 .

Nakano-Kobayashi, A., Nadif Kasri, N., Newey, S. E. , Van Aelst, L. (2009) The Rho-Linked Mental Retardation Protein OPHN1 Controls Synaptic Vesicle Endocytosis via Endophilin A1. Curr Biol, 19(13) pp. 1133-1139 .

Nadif Kasri, N., Nakano-Kobayashi, A., Malinow, R., Li, B. , Van Aelst, L. (2009) The Rho-linked mental retardation protein oligophrenin-1 controls synapse maturation and plasticity by stabilizing AMPA receptors. Genes Dev, 23(11) pp. 1289-1302.

Hu, H. L., Qin, Y., Bochorishvili, G., Zhu, Y. H., Van Aelst, L. , Zhu, J. J. (2008) Ras signaling mechanisms underlying impaired GluR1-dependent plasticity associated with fragile X syndrome. Journal of Neuroscience, 28(31) pp. 7847-7862.

Xue, W., Krasnitz, A., Lucito, R., Sordella, R., Van Aelst, L., Cordon-Cardo, C., Singer, S., Kuehnel, F., Wigler, M. H., Powers, S., Zender, L. , Lowe, S. W. (2008) DLC1 is a chromosome 8p tumor suppressor whose loss promotes hepatocellular carcinoma. Genes & Development, 22(11) pp. 1439-44.

Nadif Kasri, N., Govek, E. E. , Van Aelst, L. (2008) Characterization of Oligophrenin -1, a RhoGAP Lost in Patients Affected with Mental Retardation: Lentiviral Injection in Organotypic Brain Slice Cultures. Methods Enzymol, 439 pp. 255-266.

Nadif Kasri, N. , Van Aelst, L. (2008) Rho-linked genes and neurological disorders. Pflügers Archiv European Journal of Physiology, 455(5) pp. 787-797.

Sordella, R. , Van Aelst, L. (2008) Dialogue between RhoA/ROCK and Members of the Par Complex in Cell Polarity. Developmental Cell, 14(2) pp. 150-2.

Boettner, B. , Van Aelst, L. (2007) The Rap GTPase Activator Drosophila PDZ-GEF Regulates Cell Shape in Epithelial Migration and Morphogenesis. Mol Cell Biol, 27(22) pp. 7966-7980.

Watabe-Uchida, M., Govek, E. E. , Van Aelst, L. (2006) Regulators of Rho GTPases in neuronal development. J Neurosci, 26(42) pp. 10633-5.

Watabe-Uchida, M., John, K. A., Janas, J. A., Newey, S. E. , Van Aelst, L. (2006) The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18. Neuron, 51(6) pp. 727-39.

Zhao, M., Janas, J. A., Niki, M., Pandolfi, P. P. , Van Aelst, L. (2006) Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis. Mol Cell Biol, 26(7) pp. 2479-89.

Janas, J. A., Skowronski, J. , Van Aelst, L. (2006) Lentiviral delivery of RNAi in hippocampal neurons. Methods Enzymol, 406 pp. 593-605.

Sordella, R. , Van Aelst, L. (2006) Driving Actin Dynamics under the Influence of Alcohol. Cell, 127(1) pp. 37-39.

Yasuda, Ryohei, Harvey, Christopher D., Zhong, Haining, Sobczyk, Aleksander, Van Aelst, Linda , Svoboda, Karel (2006) Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging. Nature Neuroscience, 9(2) pp. 283-291.

Qin, Y., Zhu, Y. H., Baumgart, J. P., Stornetta, R. L., Seidenman, K., Mack, V., van Aelst, L. , Zhu, J. J. (2005) State-dependent Ras signaling and AMPA receptor trafficking. Genes & Development, 19(17) pp. 2000-2015.

Newey, S. E., Velamoor, V., Govek, E.-E. , Van Aelst, L. (2005) Rho GTPases, dendritic structure, and mental retardation. J Neurobiol, 64(1) pp. 58-74.

Govek, E. E., Newey, S. E. , Van Aelst, L. (2005) The role of the Rho GTPases in neuronal development. Genes Dev, 19(1) pp. 1-49.

Zhu, Y., Pak, D., Qin, Y., McCormack, S. G., Kim, M. J., Baumgart, J. P., Velamoor, V., Auberson, Y. P., Osten, P., Van Aelst, L., Sheng, M. , Zhu, J. J. (2005) Rap2-JNK removes synaptic AMPA receptors during depotentiation. Neuron, 46(6) pp. 905-916.

Benitah, S. A., Valeron, P. F., Van Aelst, L., Marshall, C. J. , Lacal, J. C. (2004) Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation. Biochimica Et Biophysica Acta-Reviews on Cancer, 1705(2) pp. 121-132.

Niki, M., Di Cristofano, A., Zhao, M. M., Honda, H., Hirai, H., Van Aelst, L., Cordon-Cardo, C. , Pandolfi, P. P. (2004) Role of Dok-1 and Dok-2 in leukemia suppression. Journal of Experimental Medicine, 200(12) pp. 1689-1695.

Niki, M., Di Cristofano, A., Zhao, M. M., Hirai, H., Van Aelst, L., Cordon-Cardo, C. , Pandolfi, P. P. (2004) Critical role of Dok-1 and Dok-2 in leukemia suppression. Blood, 104(11) pp. 807A-807A.

Jakubiec, A., Notaise, J., Tournier, V., Hericourt, F., Block, M. A., Drugeon, G., van Aelst, L. , Jupin, I. (2004) Assembly of turnip yellow mosaic virus replication complexes: Interaction between the proteinase and polymerase domains of the replication proteins. Journal of Virology, 78(15) pp. 7945-7957.

Van Aelst, L. , Cline, H. T. (2004) Rho GTPases and activity-dependent dendrite development. Curr Opin Neurobiol, 14(3) pp. 297-304.

Govek, E. E., Newey, S. , Van Aelst, L. (2004) Knockdown of the X-linked mental retardation protein, oligophrenin-1, affects dendritic spine morphology. Faseb Journal, 18(8) pp. C310-C310.

Govek, E. E., Newey, S. E., Akerman, C. J., Cross, J. R., Van der Veken, L. , Van Aelst, L. (2004) The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nat Neurosci, 7(4) pp. 364-72.

Boettner, B., Harjes, P., Ishimaru, S., Heke, M., Fan, H. Q., Qin, Y., Van Aelst, L. , Gaul, U. (2003) The AF-6 homolog Canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics, 165(1) pp. 159-169.

Boettner, B. , Van Aelst, L. (2002) The RASputin effect. Genes & Development, 16(16) pp. 2033-2038.

Zhu, J. J., Qin, Y., Zhao, M. M., Van Aelst, L. , Malinow, R. (2002) Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell, 110(4) pp. 443-455.

Van Aelst, L. , Symons, M. (2002) Role of Rho family GTPases in epithelial morphogenesis. Genes & Development, 16(9) pp. 1032-1054.

Schmitz, A. A., Lucito, R. , Van Aelst, L. (2002) Using cDNA-representational difference analysis (cDNA-RDA) in combination with microarrays to identify Rac regulated genes. In: GTPase Protocols: the Ras superfamily. Methods Mol Biol. Methods Mol Biol, 189 pp. 25-43.

Boettner, B., Harjes, P., Gaul, U. , Van Aelst, L. (2001) Functional interaction of the small Rap GTPase and the junctional Canoe protein during embryonic dorsal closure in Drosophila melanogaster. Molecular Biology of the Cell, 12 pp. 370A-370A.

Gumienny, T. L., Brugnera, E., Tosello-Trampont, A. C., Kinchen, J. M., Haney, L. B., Nishiwaki, K., Walk, S. F., Nemergut, M. E., Macara, I. G., Francis, R., Schedl, T., Qin, Y., Van Aelst, L., Hengartner, M. O. , Ravichandran, K. S. (2001) CED-12/ELMO, a novel member of the crkII/dock180/rac pathway, is required for phagocytosis and cell migration. Cell, 107(1) pp. 27-41.

Di Cristofano, A., Niki, M., Zhao, M. M., Karnell, F. G., Clarkson, B., Pear, W. S., Van Aelst, L. , Pandolfi, P. P. (2001) p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl). Journal of Experimental Medicine, 194(3) pp. 275-284.

Zhao, M. M., Schmitz, A. A. P., Qin, Y., Di Cristofano, A., Pandolfi, P. P. , Van Aelst, L. (2001) Phosphoinositide 3-kinase-dependent membrane recruitment of p62(dok) is essential for its negative effect on mitogen-activated protein (MAP) kinase activation. Journal of Experimental Medicine, 194(3) pp. 265-274.

Niki, M., Di Cristofano, A., Zhao, M., Karnell, F. G., Clarkson, B., Pear, W. S., Van Aelst, L. , Pandolfi, P. P. (2000) Role of p65(dok) in leukemogenesis by p210(bcr-abl). Blood, 96(11) pp. 510A-510A.

Schmitz, A. A. P., Govek, E. E., Bottner, B. , Van Aelst, L. (2000) Rho GTPases: Signaling, migration, and invasion. Experimental Cell Research, 261(1) pp. 1-12.

Boettner, B., Govek, E. E., Cross, J. , Van Aelst, L. (2000) The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proceedings of the National Academy of Sciences of the United States of America, 97(16) pp. 9064-9069.

Boshans, R. L., Szanto, S., Van Aelst, L. , D'Souza-Schorey, C. (2000) ADP-ribosylation factor 6 regulates actin cytoskeleton remodeling in coordination with Rac1 and RhoA. Molecular and Cellular Biology, 20(10) pp. 3685-3694.

Chen, R. A., Michaeli, T., Van Aelst, L. , Ballester, R. (2000) A role for the noncatalytic N terminus in the function of Cdc25, a Saccharomyces cerevisiae Ras-guanine nucleotide exchange factor. Genetics, 154(4) pp. 1473-1484.

Li, Z., Van Aelst, L. , Cline, H. T. (2000) Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo. Nature Neuroscience, 3(3) pp. 217-225.

Boettner, B. , Van Aelst, L. (1999) Rac and Cdc42 effectors. Progress in molecular and subcellular biology, 22 pp. 135-58.

Boettner, B., Govek, E. , Van Aelst, L. (1998) AF6: A binding partner and putative effector of Ras oncoproteins. Molecular Biology of the Cell, 9 pp. 462A-462A.

D'Souza-Schorey, C., Boettner, B. , Van Aelst, L. (1998) Rac1 regulates integrin-mediated cell spreading and adhesion of T lymphocytes. Molecular Biology of the Cell, 9 pp. 299A-299A.

Lin, A. W., Barradas, M., Stone, J. C., Van Aelst, L., Serrano, M. , Lowe, S. W. (1998) Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes & Development, 12(19) pp. 3008-3019.

Bagrodia, S., Taylor, S. J., Jordon, K. A., Van Aelst, L. , Cerione, R. A. (1998) A novel regulator of p21-activated kinases. Journal of Biological Chemistry, 273(37) pp. 23633-23636.

Webb, C. P., Van Aelst, L., Wigler, M. H. , Woude, G. F. (1998) Signaling pathways in Ras-mediated tumorigenicity and metastasis. Proc Natl Acad Sci U S A, 95(15) pp. 8773-8.

D'Souza-Schorey, C., Boettner, B. , Van Aelst, L. (1998) Rac regulates integrin-mediated spreading and increased adhesion of T lymphocytes. Molecular and Cellular Biology, 18(7) pp. 3936-3946.

Antonarakis, S. E. , Van Aelst, L. (1998) Mind the GAP, Rho, Rab and GDI. Nature Genetics, 19(2) pp. 106-108.

Van Aelst, L. (1998) Two-hybrid analysis of Ras-Raf interactions. Methods in Molecular Biology, 84 pp. 201-22.

Van Aelst, L. , D'Souza-Schorey, C. (1997) Rho GTPases and signaling networks. Genes and Development, 11(18) pp. 2295-322.

Joneson, T., McDonough, M., Bar-Sagi, D. , Van Aelst, L. (1996) RAC regulation of actin polymerization and proliferation by a pathway distinct from Jun kinase. Science, 274(5291) pp. 1374-1376.

Barr, M. M., Tu, H., Van Aelst, L. , Wigler, M. H. (1996) Identification of Ste4 as a potential regulator of Byr2 in the sexual response pathway of Schizosaccharomyces pombe. Mol Cell Biol, 16(10) pp. 5597-603.

Van Aelst, L., Joneson, T. , Bar-Sagi, D. (1996) Identification of a novel Rac1-interacting protein involved in membrane ruffling. Embo Journal, 15(15) pp. 3778-86.

Khosravi-Far, R., White, M. A., Westwick, J. K., Solski, P. A., Chrzanowska-Wodnicka, M., Van Aelst, L., Wigler, M. H. , Der, C. J. (1996) Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation. Mol Cell Biol, 16(7) pp. 3923-33.

White, M. A., Nicolette, C., Minden, A., Polverino, A., Van Aelst, L., Karin, M. , Wigler, M. H. (1995) Multiple Ras functions can contribute to mammalian cell transformation. Cell, 80(4) pp. 533-41.

Jung, V., Wei, W., Ballester, R., Camonis, J., Mi, S., Van Aelst, L., Wigler, M. H. , Broek, D. (1994) Two types of RAS mutants that dominantly interfere with activators of RAS. Mol Cell Biol, 14(6) pp. 3707-18.

Van Aelst, L., White, M. , Wigler, M. H. (1994) Ras partners. Cold Spring Harbor Symposia on Quantitative Biology, 59 pp. 181-186.

Van Aelst, L., Barr, M., Marcus, S., Polverino, A. , Wigler, M. H. (1993) Complex formation between RAS and RAF and other protein kinases. Proc Natl Acad Sci U S A, 90(13) pp. 6213-7.

Chardin, P., Camonis, J. H., Gale, N. W., van Aelst, L., Schlessinger, J., Wigler, M. H. , Bar-Sagi, D. (1993) Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2. Science, 260(5112) pp. 1338-1343.

Van Aelst, L., Hohmann, S., Bulaya, B., Dekoning, W., Sierkstr, L., Neves, M. J., Luyten, K., Alijo, R., Ramos, J., Coccetti, P., Martegani, E., Demagalhaesrocha, N. M., Brandao, R. L., Vandijck, P., Vanhalewyn, M., Durnez, P., Jans, A. W. H. , Thevelein, J. M. (1993) Molecular-Cloning of a Gene Involved in Glucose Sensing in the Yeast Saccharomyces-Cerevisiae. Molecular Microbiology, 8(5) pp. 927-943.