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Wu, X., Wang, S. H., Sun, J., Krainer, A. R., Hua, Y., Prior, T. W. (2017) A-44G transition in SMN2 intron 6 protects patients with spinal muscular atrophy. Hum Mol Genet. ISSN 0964-6906

Jangi, M., Fleet, C., Cullen, P., Gupta, S. V., Mekhoubad, S., Chiao, E., Allaire, N., Bennett, C. F., Rigo, F., Krainer, A. R., Hurt, J. A., Carulli, J. P., Staropoli, J. F. (2017) SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage. Proc Natl Acad Sci U S A. ISSN 0027-8424

Doktor, T. K., Hua, Y., Andersen, H. S., Broner, S., Liu, Y. H., Wieckowska, A., Dembic, M., Bruun, G. H., Krainer, A. R., Andresen, B. S. (2017) RNA-sequencing of a mouse-model of spinal muscular atrophy reveals tissue-wide changes in splicing of U12-dependent introns. Nucleic Acids Res, 45 (1). pp. 395-416. ISSN 1362-4962 (Electronic)0305-1048 (Linking)

Allemand, E., Myers, M. P., Garcia-Bernardo, J., Harel-Bellan, A., Krainer, A. R., Muchardt, C. (2016) A Broad Set of Chromatin Factors Influences Splicing. PLoS Genet, 12 (9). e1006318. ISSN 1553-7404 (Electronic)1553-7390 (Linking)

Anczukow, O., Krainer, A. R. (2016) Splicing-factor alterations in cancers. RNA, 22 (9). pp. 1285-301. ISSN 1469-9001 (Electronic)1355-8382 (Linking)

Bruun, G. H., Doktor, T. K., Borch-Jensen, J., Masuda, A., Krainer, A. R., Ohno, K., Andresen, B. S. (2016) Global identification of hnRNP A1 binding sites for SSO-based splicing modulation. BMC Biol, 14 (1). p. 54. ISSN 1741-7007 (Electronic)1741-7007 (Linking)

Arun, G., Diermeier, S., Akerman, M., Chang, K. C., Wilkinson, J. E., Hearn, S., Kim, Y., MacLeod, A. R., Krainer, A. R., Norton, L., Brogi, E., Egeblad, M., Spector, D. L. (2016) Differentiation of mammary tumors and reduction in metastasis upon Malat1 LncRNA loss. Cancer Research, 76 (Supple). ISSN 0008-5472

Nomakuchi, T. T., Rigo, F., Aznarez, I., Krainer, A. R. (2016) Antisense oligonucleotide-directed inhibition of nonsense-mediated mRNA decay. Nat Biotechnol, 34 (2). pp. 164-166. ISSN 1546-1696 (Electronic)1087-0156 (Linking)

Arun, G., Diermeier, S., Akerman, M., Chang, K. C., Wilkinson, J. E., Hearn, S., Kim, Y., MacLeod, A. R., Krainer, A. R., Norton, L., Brogi, E., Egeblad, M., Spector, D. L. (2016) Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss. Genes Dev, 30 (1). pp. 34-51. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Anczukow, O., Krainer, A. R. (2015) The spliceosome, a potential Achilles heel of MYC-driven tumors. Genome Med, 7 (1). p. 107. ISSN 1756-994X (Electronic)1756-994X (Linking)

Anczukow, O., Akerman, M., Clery, A., Wu, J., Shen, C., Shirole, N. H., Raimer, A., Sun, S., Jensen, M. A., Hua, Y., Allain, F. H., Krainer, A. R. (2015) SRSF1-Regulated Alternative Splicing in Breast Cancer. Mol Cell, 60 (1). pp. 105-17. ISSN 1097-4164 (Electronic)1097-2765 (Linking)

Akerman, M., Fregoso, O. I., Das, S., Ruse, C., Jensen, M. A., Pappin, D. J., Zhang, M. Q., Krainer, A. R. (2015) Differential connectivity of splicing activators and repressors to the human spliceosome. Genome Biol, 16 (1). p. 119. ISSN 1465-6914 (Electronic)1465-6906 (Linking)

Krainer, A. R. (2015) Splicing: still so much to learn. RNA, 21 (4). pp. 500-1. ISSN 1355-8382

Staropoli, John F., Li, Huo, Chun, Seung J., Allaire, Norm, Cullen, Patrick, Thai, Alice, Fleet, Christina M., Hua, Yimin, Bennett, C. Frank, Krainer, Adrian R., Kerr, Doug, McCampbell, Alexander, Rigo, Frank, Carulli, John P. (2015) Rescue of gene-expression changes in an induced mouse model of spinal muscular atrophy by an antisense oligonucleotide that promotes inclusion of SMN2 exon 7. Genomics, 105 (4). pp. 220-228. ISSN 0888-7543

Hua, Y., Liu, Y. H., Sahashi, K., Rigo, F., Bennett, C. F., Krainer, A. R. (2015) Motor neuron cell-nonautonomous rescue of spinal muscular atrophy phenotypes in mild and severe transgenic mouse models. Genes Dev, 29 (3). pp. 288-297. ISSN 0890-9369

Guo, Ya, Xu, Quan, Canzio, Daniele, Shou, Jia, Li, Jinhuan, Gorkin, David U, Jung, Inkyung, Wu, Haiyang, Zhai, Yanan, Tang, Yuanxiao, Lu, Yichao, Wu, Yonghu, Jia, Zhilian, Li, Wei, Zhang, Michael Q, Ren, Bing, Krainer, Adrian R, Maniatis, Tom, Wu, Qiang (2015) CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell, 162 (4). pp. 900-910. ISSN 0092-8674

Xiong, H. Y., Alipanahi, B., Lee, L. J., Bretschneider, H., Merico, D., Yuen, R. K., Hua, Y., Gueroussov, S., Najafabadi, H. S., Hughes, T. R., Morris, Q., Barash, Y., Krainer, A. R., Jojic, N., Scherer, S. W., Blencowe, B. J., Frey, B. J. (2014) RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. Science, 347 (6218). ISSN 0036-8075

Paz, S., Krainer, A. R., Caputi, M. (2014) HIV-1 transcription is regulated by splicing factor SRSF1. Nucleic Acids Research, 42 (22). pp. 13812-13823. ISSN 0305-1048

Chen, Hsu-Hsin, Welling, Maaike, Bloch, Donald B, Muñoz, Javier, Mientjes, Edwin, Chen, Xinjie, Tramp, Cody, Wu, Jie, Yabuuchi, Akiko, Chou, Yu-Fen, Buecker, Christa, Krainer, Adrian, Willemsen, Rob, Heck, Albert J, Geijsen, Niels (2014) DAZL Limits Pluripotency, Differentiation, and Apoptosis in Developing Primordial Germ Cells. Stem Cell Reports, 3 (5). pp. 892-904. ISSN 2213-6711

Senturk, S., Yao, Z., Camiolo, M., Stiles, B., Rathod, T., Walsh, A. M., Nemajerova, A., Lazzara, M. J., Altorki, N. K., Krainer, A., Moll, U. M., Lowe, S. W., Cartegni, L., Sordella, R. (2014) p53Psi is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proceedings of the National Academy of Sciences of the United States of America, 111 (32). E3287-E3296. ISSN 0027-8424

Rigo, F., Chun, S. J., Norris, D. A., Hung, G., Lee, S., Matson, J., Fey, R. A., Gaus, H., Hua, Y., Grundy, J. S., Krainer, A. R., Henry, S. P., Bennett, C. F. (2014) Pharmacology of a central nervous system delivered 2′-O-methoxyethyl- modified survival of motor neuron splicing oligonucleotide in mice and nonhuman primates. Journal of Pharmacology and Experimental Therapeutics, 350 (1). pp. 46-55. ISSN 15210103

Das, S., Krainer, A. R. (2014) Emerging functions of SRSF1, splicing factor and oncoprotein, in RNA metabolism and cancer. Molecular Cancer Research, 12 (9). pp. 1195-1204. ISSN 1541-7786

Weyn-Vanhentenryck, Sebastien M., Mele, A., Yan, Q., Sun, S., Farny, N., Zhang, Z., Xue, C., Herre, M., Silver, Pamela A., Zhang, Michael Q., Krainer, Adrian R., Darnell, Robert B., Zhang, C. (2014) HITS-CLIP and Integrative Modeling Define the Rbfox Splicing-Regulatory Network Linked to Brain Development and Autism. Cell Reports, 6 (6). pp. 1139-1152. ISSN 22111247 (ISSN)

Jensen, M. A., Wilkinson, J. E., Krainer, A. R. (2014) Splicing factor SRSF6 promotes hyperplasia of sensitized skin. Nature Structural and Molecular Biology, 21. pp. 189-197. ISSN 15459993 (ISSN)

Steijger, T., Abril, J. F., Engström, P. G., Kokocinski, F., Akerman, M., Alioto, T., Ambrosini, G., Antonarakis, S. E., Behr, J., Bertone, P., Bohnert, R., Bucher, P., Cloonan, N., Derrien, T., Djebali, S., Du, J., Dudoit, S., Gerstein, M., Gingeras, T. R., Gonzalez, D., Grimmond, S. M., Guigó, R., Habegger, L., Harrow, J., Hubbard, T. J., Iseli, C., Jean, G., Kahles, A., Lagarde, J., Leng, J., Lefebvre, G., Lewis, S., Mortazavi, A., Niermann, P., Rätsch, G., Reymond, A., Ribeca, P., Richard, H., Rougemont, J., Rozowsky, J., Sammeth, M., Sboner, A., Schulz, M. H., Searle, S. M. J., Solorzano, N. D., Solovyev, V., Stanke, M., Stevenson, B. J., Stockinger, H., Valsesia, A., Weese, D., White, S., Wold, B. J., Wu, J., Wu, T. D., Zeller, G., Zerbino, D., Zhang, M. Q. (2013) Assessment of transcript reconstruction methods for RNA-seq. Nature Methods, 10 (12). pp. 1177-1184. ISSN 15487091 (ISSN)

Sahashi, K., Ling, K. K., Hua, Y., Wilkinson, J. E., Nomakuchi, T., Rigo, F., Hung, G., Xu, D., Jiang, Y. P., Lin, R. Z., Ko, C. P., Bennett, C. F., Krainer, A. R. (2013) Pathological impact of SMN2 mis-splicing in adult SMA mice. EMBO Molecular Medicine, 5 (10). pp. 1586-1601. ISSN 17574676 (ISSN)

Kamoun, Malek, Filali, Mohammed, Murray, Michael V., Awasthi, Sita, Wadzinski, Brian E. (2013) Protein phosphatase 2A family members (PP2A and PP6) associate with U1 snRNP and the spliceosome during pre-mRNA splicing. Biochemical and Biophysical Research Communications. ISSN 0006-291X

Cléry, A., Sinha, R., Anczuków, O., Corrionero, A., Moursy, A., Daubner, G. M., Valcárcel, J., Krainer, A. R., Allain, F. H. T. (2013) Isolated pseudo-RNA-recognition motifs of SR proteins can regulate splicing using a noncanonical mode of RNA recognition. Proceedings of the National Academy of Sciences of the United States of America, 110 (30). E2802-E2811. ISSN 00278424

Fregoso, O. I., Das, S., Akerman, M., Krainer, A. R. (2013) Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence. Molecular Cell, 50 (1). pp. 56-66. ISSN 1097-2765

Roca, X., Krainer, A. R., Eperon, I. C. (2013) Pick one, but be quick: 5′ splice sites and the problems of too many choices. Genes and Development, 27 (2). pp. 129-144. ISSN 08909369 (ISSN)

Ben-Hur, V., Denichenko, P., Siegfried, Z., Maimon, A., Krainer, A., Davidson, B., Karni, R. (2013) S6K1 Alternative Splicing Modulates Its Oncogenic Activity and Regulates mTORC1. Cell Reports, 3 (1). pp. 103-115. ISSN 22111247

Wu, J., Anczukow, O., Krainer, A. R., Zhang, M. Q., Zhang, C. (2013) OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds. Nucleic Acids Research, 41 (10). pp. 5149-5163. ISSN 03051048 (ISSN)

Das, S., Fregoso, O. I., Krainer, A. R. (2013) A new path to oncogene-induced senescence: At the cross-roads of splicing and translation. Cell Cycle, 12 (10). ISSN 1551-4005 (Electronic)1551-4005 (Linking)

Krainer, A. (2012) Pre-mRNA Splicing Mechanisms, Misregulation in Disease, and Therapeutic Strategies. Blood, 120 (21). ISSN 0006-4971

Rigo, F., Hua, Y. M., Krainer, A. R., Bennett, C. F. (2012) Antisense-based therapy for the treatment of spinal muscular atrophy. Journal of Cell Biology, 199 (1). pp. 21-25. ISSN 0021-9525

Wang, Z., Jeon, H. Y., Rigo, F., Bennett, C. F., Krainer, A. R. (2012) Manipulation of PK-M mutually exclusive alternative splicing by antisense oligonucleotides. Open Biol, 2 (10). p. 120133. ISSN 2046-2441 (Electronic)2046-2441 (Linking)

Sahashi, K., Hua, Y., Ling, K. K., Hung, G., Rigo, F., Horev, G., Katsuno, M., Sobue, G., Ko, C. P., Bennett, C. F., Krainer, A. R. (2012) TSUNAMI: an antisense method to phenocopy splicing-associated diseases in animals. Genes Dev, 26 (16). pp. 1874-84. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Kumar, A., Bhandari, A., Sinha, R., Sardar, P., Goyal, P., Goswami, C., Grapputo, A. (2012) Molecular Phylogeny of OVOL Genes Illustrates a Conserved C2H2 Zinc Finger Domain Coupled by Hypervariable Unstructured Regions. PLoS ONE, 7 (6). e39399. ISSN 1932-6203

Rigo, F., Hua, Y. M., Chun, S. J., Prakash, T. P., Krainer, A. R., Bennett, C. F. (2012) Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing. Nature Chemical Biology, 8 (6). pp. 555-561. ISSN 1552-4450

Roca, X., Akerman, M., Gaus, H., Berdeja, A., Bennett, C. F., Krainer, A. R. (2012) Widespread recognition of 5' splice sites by noncanonical base-pairing to U1 snRNA involving bulged nucleotides. Genes & Development, 26 (10). pp. 1098-109. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Sela, H., Spiridon, L. N., Petrescu, A. J., Akerman, M., Mandel-Gutfreund, Y., Nevo, E., Loutre, C., Keller, B., Schulman, A. H., Fahima, T. (2012) Ancient diversity of splicing motifs and protein surfaces in the wild emmer wheat (Triticum dicoccoides) LR10 coiled coil (CC) and leucine-rich repeat (LRR) domain. Molecular Plant Pathology, 13 (3). pp. 276-287. ISSN 14646722 (ISSN)

Sun, S. Y., Zhang, Z., Fregoso, O., Krainer, A. R. (2012) Mechanisms of activation and repression by the alternative splicing factors RBFOX1/2. RNA, 18 (2). pp. 274-283. ISSN 1355-8382

Kole, R., Krainer, A. R., Altman, S. (2012) RNA therapeutics: Beyond RNA interference and antisense oligonucleotides. Nature Reviews Drug Discovery, 11 (2). pp. 125-140. ISSN 14741776 (ISSN)

Anczukow, O., Rosenberg, A. Z., Akerman, M., Das, S., Zhan, L., Karni, R., Muthuswamy, S. K., Krainer, A. R. (2012) The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation. Nature Structural Molecular Biology, 19 (2). pp. 220-228. ISSN 1545-9985 (Electronic)1545-9985 (Linking)

Hua, Y., Krainer, A. R. (2012) Antisense-mediated exon inclusion. Methods Mol Biol, 867. pp. 307-323. ISSN 1940-6029 (Electronic)1064-3745 (Linking)

Wang, Z. X., Chatterjee, D., Jeon, H. Y., Akerman, M., Vander Heiden, M. G., Cantley, L. C., Krainer, A. R. (2012) Exon-centric regulation of pyruvate kinase M alternative splicing via mutually exclusive exons. Journal of Molecular Cell Biology, 4 (2). pp. 79-87.

Das, S., Anczuków, O., Akerman, M., Krainer, A. R (2012) Oncogenic Splicing Factor SRSF1 Is a Critical Transcriptional Target of MYC. Cell Reports, 1 (2). pp. 110-117. ISSN 2211-1247

Wu, J., Akerman, M., Sun, S., McCombie, W. R., Krainer, A. R., Zhang, M. Q. (2011) SpliceTrap: a method to quantify alternative splicing under single cellular conditions. Bioinformatics, 27 (21). 3010-3016 . ISSN 1367-4803

Hua, Y., Sahashi, K., Rigo, F., Hung, G., Horev, G., Bennett, C. F., Krainer, A. R. (2011) Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model. Nature, 478 (7367). pp. 123-6. ISSN 1476-4687 (Electronic) 0028-0836 (Linking)

Rigo, F., Hua, Y. M., Chun, S. J., Krainer, A. R., Bennett, C. F. (2011) Modulation of Gene Expression By Oligonucleotide Chemistry-Dependent Recruitment of Proteins to RNA Transcripts. Nucleic Acid Therapeutics, 21 (5). A53-A54. ISSN 2159-3337

Krainer, A. R., Hua, Y. M., Sahashi, K., Rigo, F., Hung, G. N., Horev, G., Bennett, C. F. (2011) Systemic Versus CNS Delivery Of MOE Antisense Oligonucleotide to Correct Defective Splicing in a Severe Mouse Model of Spinal Muscular Atrophy. Nucleic Acid Therapeutics, 21 (5). A57-A57. ISSN 2159-3337

Kumar, A., Bhandari, A., Sinha, R., Goyal, P., Grapputo, A. (2011) Spliceosomal Intron Insertions in Genome Compacted Ray-Finned Fishes as Evident from Phylogeny of MC Receptors, Also Supported by a Few Other GPCRs. PLoS ONE, 6 (8). ISSN 1932-6203

Kubota, T., Roca, X., Kimura, T., Kokunai, Y., Nishino, I., Sakoda, S., Krainer, A. R., Takahashi, M. P. (2011) A mutation in a rare type of intron in a sodium-channel gene results in aberrant splicing and causes myotonia. Human Mutation, 32 (7). pp. 773-782. ISSN 10597794 (ISSN)

Krainer, A. R. (2011) Oligonucleotide therapeutics for correcting defective RNA splicing. FEBS Journal, 278 (Issue ). p. 11. ISSN 1742-464X

Cho, S. Y., Hoang, A., Sinha, R., Zhong, X. Y., Fu, X. D., Krainer, A. R., Ghosh, G. (2011) Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly. Proceedings of the National Academy of Sciences of the United States of America, 108 (20). pp. 8233-8238. ISSN 0027-8424

Passini, M. A., Bu, J., Richards, A. M., Kinnecom, C., Sardi, S. P., Stanek, L. M., Hua,  Y., Rigo, F., Matson, J., Hung, G., Kaye, E. M., Shihabuddin, L. S., Krainer, A. R., Bennett, C. F., Cheng, S. H. (2011) Antisense oligonucleotides delivered to the mouse CNS ameliorate symptoms of severe spinal muscular atrophy. Science Translational Medicine, 3 (72). ISSN 19466234 (ISSN)

Thorsen, K., Mansilla, F., Schepeler, T., Oster, B., Rasmussen, M. H., Dyrskjot, L., Karni, R., Akerman, M., Krainer, A. R., Laurberg, S., Andersen, C. L., Orntoft, T. F. (2011) Alternative splicing of SLC39A14 in colorectal cancer is regulated by the Wnt pathway. Molecular and Cellular Proteomics, 10 (1).

Hua, Y., Sahashi, K., Hung, G., Rigo, F., Passini, M. A., Bennett, C. F., Krainer, A. R. (2010) Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model. Genes and Development, 24 (15). pp. 1634-44. ISSN 08909369 (ISSN)

Paz, I., Akerman, M., Dror, I., Kosti, I., Mandel-Gutfreund, Y. (2010) SFmap: a web server for motif analysis and prediction of splicing factor binding sites. Nucleic Acids Research, 38 (S2). W281-W285. ISSN 03051048 (ISSN)

Wu, H., Sun, S., Tu, K., Gao, Y., Xie, B., Krainer, A. R., Zhu, J. (2010) A Splicing-Independent Function of SF2/ASF in MicroRNA Processing. Molecular Cell, 38 (1). pp. 67-77.

Sinha, R., Allemand, E., Zhang, Z., Karni, R., Myers, M. P., Krainer, A. R. (2010) Arginine Methylation Controls the Subcellular Localization and Functions of the Oncoprotein Splicing Factor SF2/ASF. Molecular and Cellular Biology, 30 (11). pp. 2762-2774. ISSN 0270-7306

Sun, S., Zhang, Z., Sinha, R., Karni, R., Krainer, A. R. (2010) SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control. Nat Struct Mol Biol, 17 (3). pp. 306-12. ISSN 1545-9985 (Electronic) 1545-9985 (Linking)

Clower, C. V., Chatterjee, D., Wang, Z. X., Cantley, L. C., Heiden, M. G. V., Krainer, A. R. (2010) The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism. Proceedings of the National Academy of Sciences of the United States of America, 107 (5). pp. 1894-1899. ISSN 0027-8424

Manley, J. L., Krainer, A. R. (2010) A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). Genes and Development, 24 (11). pp. 1073-1074.

Hastings, M. L., Berniac, J., Liu, Y. H., Abato, P., Jodelka, F. M., Barthel, L., Kumar, S., Dudley, C., Nelson, M., Larson, K., Edmonds, J., Bowser, T., Draper, M., Higgins, P., Krainer, A. R. (2009) Tetracyclines That Promote SMN2 Exon 7 Splicing as Therapeutics for Spinal Muscular Atrophy. Science Translational Medicine, 1 (5). ISSN 1946-6234

Okunola, H. L., Krainer, A. R. (2009) Cooperative-binding and splicing-repressive properties of hnRNP A1. Mol Cell Biol, 29 (20). pp. 5620-5631.

Prior, T. W., Krainer, A. R., Hua, Y., Swoboda, K. J., Snyder, P. C., Bridgeman, S. J., Burghes, A. H. M., Kissel, J. T. (2009) A Positive Modifier of Spinal Muscular Atrophy in the SMN2 Gene. The American Journal of Human Genetics, 85 (3). pp. 408-413.

De Araújo, M. M., Bonnal, S., Hastings, M. L., Krainer, A. R., Valcárcel, J. (2009) Differential 3′ splice site recognition of SMN1 and SMN2 transcripts by U2AF and U2 snRNP. RNA, 15 (4). pp. 515-523.

Khoo, B., Krainer, A. R. (2009) Splicing therapeutics in SMN2 and APOB. Current Opinion in Molecular Therapeutics, 11 (2). pp. 108-115. ISSN 1464-8431

Roca, X., Krainer, A. R. (2009) A splicing component adapted to gene silencing. Nat Biotechnol, 27 (3). pp. 250-1. ISSN 1546-1696 (Electronic)1087-0156 (Linking)

Roca, X., Krainer, A. R. (2009) Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA. Nat Struct Mol Biol, 16 (2). pp. 176-182.

Karni, R., Hippo, Y., Lowe, S. W., Krainer, A. R. (2008) The splicing-factor oncoprotein SF2/ASF activates mTORC1. Proc Natl Acad Sci U S A, 105 (40). pp. 15323-7.

Zhang, C., Zhang, Z., Castle, J., Sun, S., Johnson, J., Krainer, A. R., Zhang, M. Q. (2008) Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes Dev, 22 (18). pp. 2550-63.

Thorsen, K., Sorensen, K. D., Brems-Eskildsen, A. S., Modin, C., Gaustadnes, M., Hein, A. M. K., Kruhoffer, M., Laurberg, S., Borre, M., Wang, K., Brunak, S., Krainer, A. R., Torring, N., Dyrskjot, L., Andersen, C. L., Orntoft, T. F. (2008) Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis. Molecular & Cellular Proteomics, 7 (7). pp. 1214-1224. ISSN 1535-9476

Steitz, J. A., Dreyfuss, G., Krainer, A. R., Lamond, A. I., Matera, A. G., Padgett, R. A. (2008) Where in the cell is the minor spliceosome? Proc Natl Acad Sci U S A, 105 (25). pp. 8485-6.

Zhang, C., Li, W. H., Krainer, A. R., Zhang, M. Q. (2008) RNA landscape of evolution for optimal exon and intron discrimination. Proc Natl Acad Sci U S A, 105 (15). 5797-5802 .

Hua, Y., Vickers, T. A., Okunola, H. L., Bennett, C. F., Krainer, A. R. (2008) Antisense Masking of an hnRNP A1/A2 Intronic Splicing Silencer Corrects SMN2 Splicing in Transgenic Mice. Am J Hum Genet, 82 (4). pp. 834-48.

Majerciak, V., Yamanegi, K., Allemand, E., Kruhlak, M., Krainer, A. R., Zheng, Z. M. (2008) Kaposi sarcoma-associated herpesvirus ORF57 functions as a viral splicing factor and promotes the expression of intron-containing viral lytic genes in spliceosome-mediated RNA splicing. J Virol, 82 (6). pp. 2792-2801.

Chen, G., Li, W., Zhang, Q. S. , Regulski, M. R., Sinha, N., Barditch, J., Tully, T. , Krainer, A. R., Zhang, M. Q., Dubnau, J. T. (2008) Identification of Synaptic Targets of Drosophila Pumilio. PLoS Computational Biology, 4 (2). e1000026. ISSN 1553734X

Roca, X., Olson, A. J., Rao, A. R., Enerly, E., Kristensen, V. N., Borresen-Dale, A. L., Andresen, B. S., Krainer, A. R., Sachidanandam, R. (2008) Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics. Genome Res, 18 (1). pp. 77-87.

Zhang, C., Krainer, A. R., Zhang, M. Q. (2007) Evolutionary impact of limited splicing fidelity in mammalian genes. Trends Genet, 23 (10). pp. 484-488. ISSN 0168-9525 (Print)

Zhang, C. L., Hastings, M. L., Krainer, A. R., Zhang, M. Q. (2007) Dual-specificity splice sites function alternatively as 5 ' and 3 ' splice sites. Proceedings of the National Academy of Sciences of the United States of America, 104 (38). pp. 15028-15033. ISSN 0027-8424

Caceres, J. F., Krainer, A. R., Kornblihtt, A. R. (2007) The pathology of pre-mRNA splicing: a meeting in the Italian Alps - Workshop on pre-mRNA processing and disease. Embo Reports, 8 (8). pp. 730-734. ISSN 1469-221X

Zhang, Z., Krainer, A. R. (2007) Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components. Proc Natl Acad Sci U S A, 104 (28). pp. 11574-9. ISSN 0027-8424 (Print)

Allemand, E., Hastings, M. L., Murray, M. V., Myers, M. P., Krainer, A. R. (2007) Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid-binding protein YB-1. Nat Struct Mol Biol, 14 (7). pp. 630-638. ISSN 1545-9993 (Print)

Hastings, M. L., Allemand, E., Duelli, D. M., Myers, M. P., Krainer, A. R. (2007) Control of Pre-mRNA Splicing by the General Splicing Factors PUF60 and U2AF65. PLoS ONE, 2 (6). e538. ISSN 1932-6203 (Electronic)

Buratti, E., Chivers, M., Královičová, J., Romano, M., Baralle, M., Krainer, Adrian R., Vořechovský, I. (2007) Aberrant 5' splice sites in human disease genes: mutation pattern, nucleotide structure and comparison of computational tools that predict their utilization. Nucleic Acids Res, 35 (13). pp. 4250-4263. ISSN 1362-4962 (Electronic)

Wimmer, K., Roca, X., Beiglbock, H., Callens, T., Etzler, J., Rao, A. R., Krainer, A. R., Fonatsch, C., Messiaen, L. (2007) Extensive in silico analysis of NF1 splicing defects uncovers determinants for splicing outcome upon 5 ' splice-site disruption. Human Mutation, 28 (6). pp. 599-612. ISSN 1059-7794

Das, R., Yu, J., Zhang, Z., Gygi, M. P., Krainer, A. R., Gygi, S. P., Reed, R. (2007) SR proteins function in coupling RNAP II transcription to pre-mRNA splicing. Molecular Cell, 26 (6). pp. 867-881. ISSN 1097-2765

Hua, Y. M., Vickers, T. A., Baker, B. F., Bennett, C. F., Krainer, A. R. (2007) Enhancement of SMN2 Exon 7 inclusion by antisense oligonucleotides targeting the exon. PLoS Biology, 5 (4). e73. ISSN 1544-9173

Nielsen, K. B., Sorensen, S., Cartegni, L., Corydon, T. J., Doktor, T. K., Schroeder, L. D., Reinert, L. S., Elpeleg, O., Krainer, A. R., Gregersen, N., Kjems, J., Andresen, B. S. (2007) Seemingly neutral polymorphic variants may confer immunity to splicing-inactivating mutations: A synonymous SNP in exon 5 of MCAD protects from deleterious mutations in a flanking exonic splicing enhancer. American Journal of Human Genetics, 80 (3). pp. 416-432. ISSN 0002-9297

Karni, R., de Stanchina, E., Lowe, S. W., Sinha, R., Mu, D., Krainer, A. R. (2007) The gene encoding the splicing factor SF2/ASF is a proto-oncogene. Nat Struct Mol Biol, 14 (3). pp. 185-93. ISSN 1545-9993 (Print)

Khoo, B., Roca, X., Chew, S. L., Krainer, A. R. (2007) Antisense oligonucleotide-induced alternative splicing of the APOB mRNA generates a novel isoform of APOB. BMC Molecular Biology, 8. ISSN 1471-2199

Shaw, S. D., Chakrabarti, S., Ghosh, G., Krainer, A. R. (2007) Deletion of the N-terminus of SF2/ASF permits RS-domain-independent pre-mRNA splicing. PLoS ONE, 2 (9). e854. ISSN 1932-6203 (Electronic)

Smith, P. J., Zhang, C., Wang, J., Chew, S. L., Zhang, M. Q., Krainer, A. R. (2006) An increased specificity score matrix for the prediction of SF2/ASF-specific exonic splicing enhancers. Hum Mol Genet, 15 (16). pp. 2490-508. ISSN 0964-6906 (Print)

Zhang, Q. S. , Manche, L., Xu, R. M. , Krainer, A. R. (2006) hnRNP A1 associates with telomere ends and stimulates telomerase activity. RNA, 12 (6). pp. 1116-28. ISSN 1355-8382 (Print)

Krainer, A. R., Karni, R. (2006) Oncogenic activity of alternative splicing factors. Faseb Journal, 20 (4). A456-A456. ISSN 0892-6638

Cartegni, L., Hastings, M. L., Calarco, J. A., de Stanchina, E., Krainer, A. R. (2006) Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2. Am J Hum Genet, 78 (1). pp. 63-77. ISSN 0002-9297 (Print)

Sheth, N., Roca, X., Hastings, M. L., Roeder, T., Krainer, A. R., Sachidanandam, R. (2006) Comprehensive splice-site analysis using comparative genomics. Nucleic Acids Res, 34 (14). pp. 3955-3967. ISSN 1362-4962 (Electronic)

Madsen, P. P., Kibæk, M., Roca, X., Sachidanandam, R., Krainer, A. R., Christensen, E., Steiner, R. D., Gibson, K. M., Corydon, T. J., Knudsen, I., Wanders, R. J. A., Ruiter, J. P. N., Gregersen, N., Andresen, B. S. (2006) Short/branched-chain acyl-CoA dehydrogenase deficiency due to an IVS3+3A>G mutation that causes exon skipping. Human Genetics, 118 (6). pp. 680-690. ISSN 03406717

Kimura, H., Takizawa, N., Allemand, E., Hori, T., Iborra, F. J., Nozaki, N., Muraki, M., Hagiwara, M., Krainer, A. R., Fukagawa, T., Okawa, K. (2006) A novel histone exchange factor, protein phosphatase 2Cgamma, mediates the exchange and dephosphorylation of H2A-H2B. Journal of Cell Biology, 175 (3). pp. 389-400. ISSN 00219525

Tyson-Capper, A. J., Bailey, J., Krainer, A. R., Robson, S. C., Europe-Finner, G. N. (2005) The switch in alternative splicing of cyclic AMP-response element modulator protein CREM tau(2)alpha (activator) to CREM alpha (repressor) in human myometrial cells is mediated by SRp40. Journal of Biological Chemistry, 280 (41). pp. 34521-34529. ISSN 0021-9258

Roca, Xavier, Sachidanandam, Ravi, Krainer, Adrian R. (2005) Determinants of the inherent strength of human 5' splice sites. Rna, 11 (5). pp. 683-98. ISSN 1355-8382 (Print)

Allemand, E., Guil, S., Myers, M., Moscat, J., Caceres, J. F., Krainer, A. R. (2005) Regulation of heterogenous nuclear ribonucleoprotein A1 transport by phosphorylation in cells stressed by osmotic shock. Proc Natl Acad Sci U S A, 102 (10). pp. 3605-10. ISSN 0027-8424 (Print)

Hastings, M. L., Resta, N., Traum, D., Stella, A., Guanti, G., Krainer, A. R. (2005) An LKB1 AT-AC intron mutation causes Peutz-Jeghers syndrome via splicing at noncanonical cryptic splice sites. Nat Struct Mol Biol, 12 (1). pp. 54-9. ISSN 1545-9993 (Print)

Wang, J., Smith, P. J., Krainer, A. R., Zhang, M. Q. (2005) Distribution of SR protein exonic splicing enhancer motifs in human protein-coding genes. Nucleic Acids Res, 33 (16). pp. 5053-62. ISSN 1362-4962 (Electronic)

Coutinho, G., Xie, J. Y., Du, L. T., Brusco, A., Krainer, A. R., Gatti, R. A. (2005) Functional significance of deep intronic mutation in the ATM gene and evidence for an alternative Exon 28a. Human Mutation, 25 (2). pp. 118-124. ISSN 1059-7794

Zhang, Z., Krainer, A. R. (2004) Involvement of SR proteins in mRNA surveillance. Molecular Cell, 16 (4). pp. 597-607. ISSN 1097-2765

Muraki, M., Ohkawara, B., Hosoya, T., Onogi, H., Koizumi, J., Koizumi, T., Sumi, K., Jun-ichiro, Y., Murray, M. V., Kimura, H., Furuichi, K., Shibuya, H., Krainer, A. R., Suzuki, M., Hagiwara, M. (2004) Manipulation of alternative splicing by a newly developed inhibitor of Clks. Journal of Biological Chemistry, 279 (23). pp. 24246-24254. ISSN 0021-9258

Zatkova, A., Messiaen, L., Vandenbroucke, I., Wieser, R., Fonatsch, C., Krainer, A. R., Wimmer, K. (2004) Disruption of exonic splicing enhancer elements is the principal cause of exon skipping associated with seven nonsense or missense alleles of NF1. Human Mutation, 24 (6). pp. 491-501. ISSN 1059-7794

Domsic, J. K., Wang, Y. B., Mayeda, A., Krainer, A. R., Stoltzfus, C. M. (2003) Human immunodeficiency virus type 1 hnRNP A/B-Dep endent exonic splicing silencer ESSV antagonizes binding of U2AF65 to viral polypyrimidine tracts. Molecular and Cellular Biology, 23 (23). pp. 8762-8772. ISSN 0270-7306

Roca, X., Sachidanandam, R., Krainer, A. R. (2003) Intrinsic differences between authentic and cryptic 5 ' splice sites. Nucleic Acids Research, 31 (21). pp. 6321-6333. ISSN 0305-1048

Cartegni, L., Wang, J. H., Zhu, Z. W., Zhang, M. Q., Krainer, A. R. (2003) ESEfinder: a web resource to identify exonic splicing enhancers. Nucleic Acids Research, 31 (13). pp. 3568-3571. ISSN 0305-1048

Cartegni, L., Krainer, A. R. (2003) Correction of disease-associated exon skipping by synthetic exon-specific activators. Nature Structural Biology, 10 (2). pp. 120-125. ISSN 1072-8368

Hou, V. C., Lersch, R., Gee, S. L., Ponthier, J. L., Lo, A. J., Wu, M., Turck, C. W., Koury, M., Krainer, A. R., Mayeda, A., Conboy, J. G. (2002) Decrease in hnRNP A/B expression during erythropoiesis mediates a pre-mRNA splicing switch. Embo Journal, 21 (22). pp. 6195-6204. ISSN 0261-4189

Cazalla, D., Zhu, J., Manche, L., Huber, E., Krainer, A. R., Caceres, J. F. (2002) Nuclear export and retention signals in the RS domain of SR proteins. Molecular and Cellular Biology, 22 (19). pp. 6871-6882. ISSN 0270-7306

Andresen, B. S., Nielsen, K. B., Madsen, P. P., Corydon, T. J., Kjems, J., Krainer, A. R., Elpeleg, O. N., Schroeder, L. D., Gregersen, N. (2002) Simple mutations in the coding region of three acyl-CoA dehydrogenase genes may lead to skipping of the constitutive exon due to disruption of potential splice enhancer sequences or mRNA secondary structures. American Journal of Human Genetics, 71 (4). p. 196. ISSN 0002-9297

Fackenthal, J. D., Cartegni, L., Krainer, A. R., Olopade, O. I. (2002) BRCA2 T2722R is a deleterious allele that causes exon skipping. American Journal of Human Genetics, 71 (3). pp. 625-631. ISSN 0002-9297

Pollard, A. J., Krainer, A. R., Robson, S. C., Europe-Finner, G. N. (2002) Alternative splicing of the adenylyl cyclase stimulatory G-protein G alpha(s) is regulated by SF2/ASF and heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) and involves the use of an unusual TG 3'-splice Site. Journal of Biological Chemistry, 277 (18). pp. 15241-51. ISSN 0021-9258 (Print)0021-9258

Vitali, J., Ding, J. Z., Jiang, J. Z., Zhang, Y., Krainer, A. R., Xu, R. M. (2002) Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1. Nucleic Acids Research, 30 (7). pp. 1531-1538. ISSN 0305-1048

Cartegni, L., Krainer, A. R. (2002) Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1. Nature Genetics, 30 (4). pp. 377-384. ISSN 1061-4036

Cartegni, L., Chew, S. L., Krainer, A. R. (2002) Listening to silence and understanding nonsense: Exonic mutations that affect splicing. Nature Reviews Genetics, 3 (4). pp. 285-298. ISSN 1471-0056

Dance, G. S. C., Sowden, M. P., Cartegni, L., Cooper, E., Krainer, A. R., Smith, H. C. (2002) Two proteins essential for apolipoprotein B mRNA editing are expressed from a single gene through alternative splicing. Journal of Biological Chemistry, 277 (15). pp. 12703-12709. ISSN 0021-9258

Smith, P. J., Spurrell, E. L., Coakley, J., Hinds, C. J., Ross, R. J. M., Krainer, A. R., Chew, S. L. (2002) An exonic splicing enhancer in human IGF-I pre-mRNA mediates recognition of alternative exon 5 by the serine-arginine protein splicing factor-2/alternative splicing factor. Endocrinology, 143 (1). pp. 146-154. ISSN 0013-7227

Zhu, J., Mayeda, A., Krainer, A. R. (2001) Exon identity established through differential antagonism between exonic splicing silencer-bound hnRNP A1 and enhancer-bound SR proteins. Molecular Cell, 8 (6). pp. 1351-1361. ISSN 1097-2765

Hou, V. C., Gee, S. L., Wu, M., Turck, C. W., Koury, M., Krainer, A. R., Mayeda, A., Conboy, J. G. (2001) Characterization of a second hnRNP A/B-dependent exonic splicing silencer in protein 4.1R exon 16. Blood, 98 (11). 436A-436A. ISSN 0006-4971

Bilodeau, P. S., Domsic, J. K., Mayeda, A., Krainer, A. R., Stoltzfus, C. M. (2001) RNA splicing at human immunodeficiency virus type 1 3 ' splice site A2 is regulated by binding of hnRNP A/B proteins to an exonic splicing silencer element. Journal of Virology, 75 (18). pp. 8487-8497. ISSN 0022-538X

Hastings, M. L., Krainer, A. R. (2001) Pre-mRNA splicing in the new millennium. Current Opinion in Cell Biology, 13 (3). pp. 302-309. ISSN 0955-0674

Hastings, M. L., Krainer, A. R. (2001) Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway. RNA, 7 (3). pp. 471-482. ISSN 1355-8382

Nilsson, C. E., Petersen-Mahrt, S., Durot, C., Shtrichman, R., Krainer, A. R., Kleinberger, T., Akusjarvi, G. (2001) The adenovirus E4-ORF4 splicing enhancer protein interacts with a subset of phosphorylated SR proteins. EMBO Journal, 20 (4). pp. 864-871. ISSN 0261-4189

Liu, H. X., Cartegni, L., Zhang, M. Q., Krainer, A. R. (2001) A mechanism for exon skipping caused by nonsense or missense mutations in BRCA1 and other genes. Nature Genetics, 27 (1). pp. 55-58. ISSN 1061-4036

Zhu, J., Krainer, A. R. (2000) Pre-mRNA splicing in the absence of an SR protein RS domain. Genes & Development, 14 (24). pp. 3166-3178. ISSN 0890-9369

Eperon, I. C., Makarova, O. V., Mayeda, A., Munroe, S. H., Caceres, J. F., Hayward, D. G., Krainer, A. R. (2000) Selection of alternative 5 ' splice sites: Role of U1 snRNP and models for the antagonistic effects of SF2/ASF and hnRNP A1. Molecular and Cellular Biology, 20 (22). pp. 8303-8318. ISSN 0270-7306

Van Scoy, S., Watakabe, I., Krainer, A. R., Hearing, J. (2000) Human p32: A coactivator for Epstein-Barr virus nuclear antigen-1-mediated transcriptional activation and possible role in viral latent cycle DNA replication. Virology, 275 (1). pp. 145-157. ISSN 0042-6822

Dirksen, W. P., Li, X. L., Mayeda, A., Krainer, A. R., Rottman, F. M. (2000) Mapping the SF2/ASF binding sites in the bovine growth hormone exonic splicing enhancer. Journal of Biological Chemistry, 275 (37). pp. 29170-29177. ISSN 0021-9258

Boudrez, A., Beullens, M., Groenen, P., Van Eynde, A., Vulsteke, V., Jagiello, I., Murray, M., Krainer, A. R., Stalmans, W., Bollen, M. (2000) NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry. Journal of Biological Chemistry, 275 (33). pp. 25411-25417. ISSN 0021-9258

Pollard, A. J., Sparey, C., Robson, S. C., Krainer, A. R., Europe-Finner, G. N. (2000) Spatio-temporal expression of the trans-acting splicing factors SF2/ASF and heterogeneous ribonuclear proteins A1/A1(B) in the myometrium of the pregnant human uterus: A molecular mechanism for regulating regional protein isoform expression in vivo. Journal of Clinical Endocrinology & Metabolism, 85 (5). pp. 1928-1936. ISSN 0021-972X

van Oordt, W. V., Diaz-Meco, M. T., Lozano, J., Krainer, A. R., Moscat, J., Caceres, J. F. (2000) The MKK3/6-p38-signaling cascade alters the subcellular distribution of hnRNP A1 and modulates alternative splicing regulation. Journal of Cell Biology, 149 (2). pp. 307-316. ISSN 0021-9525

Liu, H. X., Chew, S. L., Cartegni, L., Zhang, M. Q., Krainer, A. R. (2000) Exonic splicing enhancer motif recognized by human SC35 under splicing conditions. Molecular and Cellular Biology, 20 (3). pp. 1063-1071. ISSN 0270-7306

Burns, C. G., Ohi, R., Krainer, A. R., Gould, K. L. (1999) Evidence that Myb-related CDC5 proteins are required for pre-mRNA splicing. Proceedings of the National Academy of Sciences of the United States of America, 96 (24). pp. 13789-13794. ISSN 0027-8424

Chew, S. L., Liu, H. X., Mayeda, A., Krainer, A. R. (1999) Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing. Proceedings of the National Academy of Sciences of the United States of America, 96 (19). pp. 10655-10660. ISSN 0027-8424

Mayeda, A., Badolato, J., Kobayashi, R., Zhang, M. Q., Gardiner, E. M., Krainer, A. R. (1999) Purification and characterization of human RNPS1: a general activator of pre-mRNA splicing. EMBO Journal, 18 (16). pp. 4560-4570. ISSN 0261-4189

Ismaili, N., Perez-Morga, D., Walsh, P., Mayeda, A., Pays, A., Tebabi, P., Krainer, A. R., Pays, E. (1999) Characterization of a SR protein from Trypanosoma brucei with homology to RNA-binding cis-splicing proteins. Molecular and Biochemical Parasitology, 102 (1). pp. 103-115. ISSN 0166-6851

Caputi, M., Mayeda, A., Krainer, A. R., Zahler, A. M. (1999) hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing. EMBO Journal, 18 (14). pp. 4060-4067. ISSN 0261-4189

Wu, Q., Krainer, A. R. (1999) AT-AC Pre-mRNA splicing mechanisms and conservation of minor introns in voltage-gated ion channel genes. Molecular and Cellular Biology, 19 (5). pp. 3225-3236. ISSN 0270-7306

Ding, J. Z., Hayashi, M. K., Zhang, Y., Manche, L., Krainer, A. R., Xu, R. M. (1999) Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNA. Genes & Development, 13 (9). pp. 1102-1115. ISSN 0890-9369

Lopato, S., Kalyna, M., Dorner, S., Kobayashi, R., Krainer, A. R., Barta, A. (1999) atSRp30, one of two SF2/ASF-like proteins from Arabidopsis thaliana, regulates splicing of specific plant genes. Genes & Development, 13 (8). pp. 987-1001. ISSN 0890-9369

Koizumi, J., Okamoto, Y., Onogi, H., Mayeda, A., Krainer, A. R., Hagiwara, M. (1999) The subcellular localization of SF2/ASF is regulated by direct interaction with SR protein kinases (SRPKs). Journal of Biological Chemistry, 274 (16). pp. 11125-11131. ISSN 0021-9258

Jiang, J., Zhang, Y., Krainer, A. R., Xu, R. M. (1999) Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein. Proceedings of the National Academy of Sciences of the United States of America, 96 (7). pp. 3572-7. ISSN 0027-8424 (Print)0027-8424

Mayeda, A., Screaton, G. R., Chandler, S. D., Fu, X. D., Krainer, A. R. (1999) Substrate specificities of SR proteins in constitutive splicing are determined by their RNA recognition motifs and composite pre-mRNA exonic elements. Molecular and Cellular Biology, 19 (3). pp. 1853-1863. ISSN 0270-7306

Murray, M. V., Kobayashi, R., Krainer, A. R. (1999) The type 2C Ser/Thr phosphatase PP2C gamma is a pre-mRNA splicing factor. Genes & Development, 13 (1). pp. 87-97. ISSN 0890-9369

Mayeda, A., Krainer, A. R. (1999) Mammalian in vitro splicing assays. Methods in Molecular Biology, 118. pp. 315-21. ISSN 1064-3745 (Print)1064-3745

Mayeda, A., Krainer, A. R. (1999) Preparation of HeLa cell nuclear and cytosolic S100 extracts for in vitro splicing. Methods in Molecular Biology, 118. pp. 309-14. ISSN 1064-3745 (Print)1064-3745

Murray, M. V. (1999) Role of phosphorylation in pre-mRNA splicing. Frontiers of Hormone Research, 25. pp. 83-100. ISSN 0301-3073 (Print)

Wu, Q., Krainer, A. R. (1998) Purine-rich enhancers function in the AT-AC pre-mRNA splicing pathway and do so independently of intact U1 snRNP. RNA, 4 (12). pp. 1664-1673. ISSN 1355-8382

Mayeda, A., Munroe, S. H., Xu, R. M., Krainer, A. R. (1998) Distinct functions of the closely related tandem RNA-recognition motifs of hnRNP A1. RNA, 4 (9). pp. 1111-1123. ISSN 1355-8382

Liu, H. X., Zhang, M., Krainer, A. R. (1998) Identification of functional exonic splicing enhancer motifs recognized by individual SR proteins. Genes & Development, 12 (13). pp. 1998-2012. ISSN 0890-9369

Hanamura, A., Caceres, J. F., Mayeda, A., Franza, B. R., Krainer, A. R. (1998) Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors. RNA, 4 (4). pp. 430-444. ISSN 1355-8382

Caceres, J. F., Screaton, G. R., Krainer, A. R. (1998) A specific subset of SR proteins shuttles continuously between the nucleus and the cytoplasm. Genes & Development, 12 (1). pp. 55-66. ISSN 0890-9369

Misteli, T., Cáceres, J. F., Clement, J. Q., Krainer, A. R., Wilkinson, M. F., Spector, D. L. (1998) Serine phosphorylation of SR proteins is required for their recruitment to sites of transcription in vivo. Journal of Cell Biology, 143 (2). pp. 297-307. ISSN 0021-9525

Horowitz, D. S., Kobayashi, R., Krainer, A. R. (1997) A new cyclophilin and the human homologues of yeast Prp3 and Prp4 form a complex associated with U4/U6 snRNPs. Rna-a Publication of the Rna Society, 3 (12). pp. 1374-1387. ISSN 1355-8382

Misteli, T., Cáceres, J. F., Krainer, A. R., Spector, D. L. (1997) The control of splicing factor recruitment to sites of transcription in-vivo. Molecular Biology of the Cell, 8. p. 597. ISSN 1059-1524

Jokhan, L., Dong, A. P., Mayeda, A., Krainer, A. R., Xu, R. M. (1997) Crystallization and preliminary X-ray diffraction studies of UP1, the two-RRM domain of hnRNP A1. Acta Crystallographica Section D-Biological Crystallography, 53. pp. 615-618. ISSN 0907-4449

Cáceres, J. F., Misteli, T., Screaton, G. R., Spector, D. L., Krainer, A. R. (1997) Role of the modular domains of SR proteins in subnuclear localization and alternative splicing specificity. Journal of Cell Biology, 138 (2). pp. 225-38. ISSN 0021-9525

Wu, Q., Krainer, A. R. (1997) Splicing of a divergent subclass of AT-AC introns requires the major spliceosomal snRNAs. RNA, 3 (6). pp. 586-601. ISSN 13558382 (ISSN)

Xu, R. M., Jokhan, L., Cheng, X., Mayeda, A., Krainer, A. R. (1997) Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs. Structure, 5 (4). pp. 559-70. ISSN 0969-2126 (Print)0969-2126

Chandler, S. D., Mayeda, A., Yeakley, J. M., Krainer, A. R., Fu, X. D. (1997) RNA splicing specificity determined by the coordinated action of RNA recognition motifs in SR proteins. Proceedings of the National Academy of Sciences of the United States of America, 94 (8). pp. 3596-3601. ISSN 0027-8424

Basu, A., Dong, B., Krainer, A. R., Howe, C. C. (1997) The intracisternal A-particle proximal enhancer-binding protein activates transcription and is identical to the RNA- and DNA-binding protein p54nrb/NonO. Molecular and Cellular Biology, 17 (2). pp. 677-86. ISSN 0270-7306 (Print)0270-7306

Horowitz, D. S., Krainer, A. R. (1997) A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor. Genes & Development, 11 (1). pp. 139-151. ISSN 0890-9369

Huang, S., Mayeda, A., Krainer, A. R., Spector, D. L. (1997) RCC1 and nuclear organization. Molecular Biology of the Cell, 8 (6). pp. 1143-1157. ISSN 1059-1524

Tseng, T. I., Krainer, A. R. (1996) Defining and characterizing the functions of RS domains in yeast. Molecular Biology of the Cell, 7. p. 3661. ISSN 1059-1524

Wu, Q., Krainer, A. R. (1996) U1-mediated exon definition interactions between AT-AC and GT-AG introns. Science, 274 (5289). pp. 1005-1008. ISSN 0036-8075

Lopato, S., Mayeda, A., Krainer, A. R., Barta, A. (1996) Pre-mRNA splicing in plants: Characterization of Ser Arg splicing factors. Proceedings of the National Academy of Sciences of the United States of America, 93 (7). pp. 3074-3079. ISSN 0027-8424

Screaton, G. R., Caceres, J. F., Mayeda, A., Bell, M. V., Plebanski, M., Jackson, D. G., Bell, J. I., Krainer, A. R. (1995) Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. EMBO Journal, 14 (17). pp. 4336-4349. ISSN 0261-4189

Mayeda, A., Munroe, S. H., Caceres, J. F., Krainer, A. R. (1994) Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins. EMBO Journal, 13 (22). pp. 5483-5495. ISSN 0261-4189

Caceres, J. F., Stamm, S., Helfman, D. M., Krainer, A. R. (1994) Regulation of alternative splicing in vivo by overexpression of antagonistic splicing factors. Science, 265 (5179). pp. 1706-9. ISSN 0036-8075 (Print)0036-8075

Horowitz, D. S., Krainer, A. R. (1994) Mechanisms for selecting 5' splice sites in mammalian pre-mRNA splicing. Trends in Genetics, 10 (3). pp. 100-106. ISSN 0168-9525

Monroe, S. H., Mayeda, A., Krainer, A. R. (1994) Role of hnRNP A1 structural domains in messenger-RNA splicing and RNA-RNA annealing. Journal of Cellular Biochemistry. p. 116. ISSN 0730-2312

Huang, M., Rech, J. E., Northington, S. J., Flicker, P. F., Mayeda, A., Krainer, A. R., Lestourgeon, W. M. (1994) The C-protein tetramer binds 230 to 240 nucleotides of pre-mRNA and nucleates the assembly of 40S heterogeneous nuclear ribonucleoprotein particles. Molecular and Cellular Biology, 14 (1). pp. 518-533. ISSN 0270-7306

Stamm, S., Mulligan, G. J., Krainer, A. R., Helfman, D. M. (1994) Non-radioactive detection of m3G capped RNAs by immunoblotting. Nucleic Acids Research, 22 (2). pp. 252-253. ISSN 0305-1048

O'Keefe, R. T., Mayeda, A., Sadowski, C. L., Krainer, A. R., Spector, D. L. (1994) Disruption of pre-mRNA splicing in vivo results in reorganization of splicing factors. Journal of Cell Biology, 124 (3). pp. 249-260. ISSN 0021-9525

Birney, E., Kumar, S., Krainer, A. R. (1993) Analysis of the RNA-recognition motif and RS and RGG domains: conservation in metazoan pre-mRNA splicing factors. Nucleic Acids Research, 21 (25). pp. 5803-5816. ISSN 0305-1048

Caceres, J. F., Krainer, A. R. (1993) Functional analysis of pre-mRNA splicing factor SF2/ASF structural domains. EMBO Journal, 12 (12). pp. 4715-4726. ISSN 0261-4189

Sun, Q., Mayeda, A., Hampson, R. K., Krainer, A. R., Rottman, F. M. (1993) General splicing factor SF2/ASF promotes alternative splicing by binding to an exonic splicing enhancer. Genes & Development, 7 (12b). pp. 2598-608. ISSN 0890-9369 (Print)0890-9369

Eperon, I. C., Ireland, D. C., Smith, R. A., Mayeda, A., Krainer, A. R. (1993) Pathways for selection of 5' splice sites by U1 snRNPs and SF2/ASF. EMBO Journal, 12 (9). pp. 3607-3617. ISSN 0261-4189

Dong, B. H., Horowitz, D. S., Kobayashi, R., Krainer, A. R. (1993) Purification and cDNA cloning of HeLa cell p54nrb, a nuclear protein with two RNA recognition motifs and extensive homology to human splicing factor PSF and Drosophila NONA/BJ6. Nucleic Acids Research, 21 (17). pp. 4085-4092. ISSN 0305-1048

Mayeda, A., Helfman, D. M., Krainer, A. R. (1993) Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF. Molecular and Cellular Biology, 13 (5). pp. 2993-3001. ISSN 0270-7306 (Print)0270-7306

Fu, X. D., Mayeda, A., Maniatis, T., Krainer, A. R. (1992) General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection. Proceedings of the National Academy of Sciences of the United States of America, 89 (23). pp. 11224-8. ISSN 0027-8424 (Print)0027-8424

Amero, S. A., Raychaudhuri, G., Cass, C. L., Vanvenrooij, W. J., Habets, W. J., Krainer, A. R., Beyer, A. L. (1992) Independent deposition of heterogeneous nuclear ribonucleoproteins and small nuclear ribonucleoprotein particles at sites of transcription. Proceedings of the National Academy of Sciences of the United States of America, 89 (18). pp. 8409-8413. ISSN 0027-8424

Birney, E., Kumar, S., Krainer, A. R. (1992) A putative homolog of U2AF65 in S. cerevisiae. Nucleic Acids Research, 20 (17). p. 4663. ISSN 0305-1048

Mayeda, A., Zahler, A. M., Krainer, A. R., Roth, M. B. (1992) Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. Proceedings of the National Academy of Sciences of the United States of America, 89 (4). pp. 1301-1304. ISSN 0027-8424

Mayeda, A., Krainer, A. R. (1992) Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2. Cell, 68 (2). pp. 365-75. ISSN 0092-8674 (Print)0092-8674

Krainer, A. R., Mayeda, A., Kozak, D., Binns, G. (1991) Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U1 70K, and Drosophila splicing regulators. Cell, 66 (2). pp. 383-394. ISSN 0092-8674

Mayeda, A., Krainer, A. R. (1991) Long-term storage of concentrated tris-borate-EDTA electrophoresis buffers without precipitation. Biotechniques, 10 (2). p. 182. ISSN 0736-6205

Krainer, A. R., Mayeda, A., Helfman, D., Conway, G. C., Kozak, D. (1991) Biochemistry of Mammalian Nuclear Pre-Messenger Rna Splicing and Splice Site Selection. Journal of Cellular Biochemistry, 47 (Suppl ). p. 45.

Krainer, A. R., Conway, G. C., Kozak, D. (1990) Purification and characterization of pre-mRNA splicing factor SF2 from HeLa cells. Genes & Development, 4 (7). pp. 1158-1171. ISSN 0890-9369

Krainer, A. R., Conway, G. C., Kozak, D. (1990) The essential pre-mRNA splicing factor SF2 influences 5' splice site selection by activating proximal sites. Cell, 62 (1). pp. 35-42. ISSN 0092-8674

Conway, G. C., Krainer, A. R., Spector, D. L., Roberts, R. J. (1989) Multiple splicing factors are released from endogenous complexes during in vitro pre-mRNA splicing. Molecular & Cellular Biology, 9 (12). pp. 5273-80. ISSN 0270-7306

Tschudi, C., Krainer, A. R., Ullu, E. (1988) The U6 small nuclear RNA from Trypanosoma brucei. Nucleic Acids Research, 16 (23). p. 11375. ISSN 0305-1048

Krainer, A. R. (1988) Pre-mRNA splicing by complementation with purified human U1, U2, U4/U6 and U5 snRNPs. Nucleic Acids Research, 16 (20). pp. 9415-9429. ISSN 0305-1048

Krainer, A. R., Maniatis, T. (1985) Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro. Cell, 42 (3). pp. 725-36. ISSN 0092-8674 (Print)0092-8674

Ruskin, B., Krainer, A. R., Maniatis, T., Green, M. R. (1984) Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro. Cell, 38 (1). pp. 317-31. ISSN 0092-8674 (Print)0092-8674

Krainer, A. R., Maniatis, T., Ruskin, B., Green, M. R. (1984) Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro. Cell, 36 (4). pp. 993-1005. ISSN 0092-8674 (Print)0092-8674

Squires, C., Krainer, A., Barry, G., Shen, W. F., Squires, C. L. (1981) Nucleotide sequence at the end of the gene for the RNA polymerase beta' subunit (rpoC). Nucleic Acids Research, 9 (24). pp. 6827-40. ISSN 0305-1048 (Print)0305-1048

Book Section

Hua, Yimin, Sahashi, Kentaro, Rigo, Frank, Hung, Gene, Bennett, C. Frank, Krainer, AdrianR (2013) Correction of RNA Splicing with Antisense Oligonucleotides as a Therapeutic Strategy for a Neurodegenerative Disease. In: Chembiomolecular Science. Springer Japan, pp. 301-313. ISBN 978-4-431-54037-3

Roca, X., Krainer, A. R. (2013) RNA Splicing. In: Brenner's Encyclopedia of Genetics. Elsevier Science. ISBN 9780080961569

Mayeda, A., Krainer, A. R. (2012) In vitro splicing assays. In: Alternative pre-mRNA Splicing: Theory and Protocols. Wiley, pp. 321-330. ISBN 9783527636785

Andresen, B. S., Krainer, A. R. (2009) When the genetic code is not enough: How sequence variations can affect pre-mRNA splicing and cause (complex) disease. In: Genetics of Complex Human Diseases: A Laboratory Manual. Cold Spring Harbor Laboratory Press, pp. 165-182. ISBN 9780879698836

Zhang, Z., Krainer, A. R. (2006) Nonsense-Mediated Alternative Splicing. In: Nonsense-mediated mRNA decay. Landes Bioscience, Georgetown, TX, pp. 250-359. ISBN 9781587062964

Caceres, J. F., Krainer, A. R. (1997) Mammalian pre-mRNA splicing factors. In: Eukaryotic mRNA processing. IRL Press at Oxford University Press. ISBN 9780199634187

Eperon, I. C., Krainer, A. R. (1994) Splicing of mRNA precursors in mammalian cells. In: RNA Processing, a practical approach. IRL, Oxford, pp. 57-101. ISBN 9780199633432

Krainer, A. R., Maniatis, T. (1988) RNA splicing. In: Frontiers in Molecular Biology: Transcription and splicing. IRL Press, Oxford, pp. 131-206. ISBN 9781852210809

Krainer, A. R., Reed, R., Maniatis, T. (1985) Mechanisms of human β-globin pre-mRNA splicing. In: Proceedings of the Robert A. Welch Foundation Conferences on Chemical Research. Robert A. Welch Foundation, pp. 353-378. ISBN 0557-1588

Krainer, A. R., Reed, R., Maniatis, T. (1985) Sequences and factors involved in pre-mRNA splicing in vitro. In: Sequence specificity in transcription and translation: proceedings of a conference from a UCLA symposium held in Steamboat Springs, Colorado, April, 1985. A.R. Liss, New York, pp. 461-473. ISBN 9780845126295

Conference or Workshop Item

Kole, R., Krainer, A. R., Sullenger, B. (2010) RNA & OLIGONUCLEOTIDE THERAPEUTICS. In: 2010 meeting on RNA & OLIGONUCLEOTIDE THERAPEUTICS, April 7–April 10, 2010, Cold Spring Harbor.

Book

Krainer, Adrian (1997) Eukaryotic mRNA processing. IRL Press at Oxford University Press. ISBN 9780199634187

Thesis

Wang, Zhenxun (2012) The mechanism and manipulation of PK-M alternative splicing. PhD thesis, Cold Spring Harbor Laboratory.

Fregoso, O. I. (2010) Elucidating the Functions of Splicing Regulatory Proteins Through the Use of High-Throughput Proteomics. PhD thesis, Cold Spring Harbor Laboratory.

Video

Krainer, A. R. (2011) Talk from Adrian Krainer at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)

This list was generated on Wed Jul 26 20:44:30 2017 EDT.
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