Items where Subject is "signal transduction"

A

Albrengues, J., Shields, M. A., Ng, D., Park, C. G., Ambrico, A., Poindexter, M. E., Upadhyay, P., Uyeminami, D. L., Pommier, A., Kuttner, V., Bruzas, E., Maiorino, L., Bautista, C., Carmona, E. M., Gimotty, P. A., Fearon, D. T., Chang, K., Lyons, S. K., Pinkerton, K. E., Trotman, L. C., Goldberg, M. S., Yeh, J. T., Egeblad, M. (September 2018) Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science, 361 (6409). ISSN 0036-8075

Arun, G., Diermeier, S. D., Spector, D. L. (February 2018) Therapeutic Targeting of Long Non-Coding RNAs in Cancer. Trends Mol Med, 24 (3). pp. 257-277. ISSN 1471-4914

B

Ballouz, Sara, Mangala, Melissa M, Perry, Matthew D, Heitmann, Stewart, Gillis, Jesse A, Hill, Adam P, Vandenberg, Jamie I (October 2020) Co-expression of calcium and hERG potassium channels reduces the incidence of proarrhythmic events. Cardiovascular Research. ISSN 0008-6363

Bar-Sagi, D. (1995) Mammalian cell microinjection assay. Methods Enzymol, 255. pp. 436-42. ISSN 0076-6879 (Print)

Bar-Sagi, D., Rotin, D., Batzer, A., Mandiyan, V., Schlessinger, J. (July 1993) SH3 domains direct cellular localization of signaling molecules. Cell, 74 (1). pp. 83-91. ISSN 0092-8674 (Print)

Belousov, V. V., Enikolopov, G. N., Mishina, N. M. (July 2013) Compartmentalization of ROS-mediated signal transduction. Russian Journal of Bioorganic Chemistry, 39 (4). pp. 341-355. ISSN 10681620

Beyaz, S., Yilmaz, O. H. (December 2016) Molecular Pathways: Dietary Regulation of Stemness and Tumor Initiation by the PPAR-delta Pathway. Clin Cancer Res, 22 (23). pp. 5636-5641. ISSN 1078-0432 (Print)1078-0432 (Linking)

Bhatia, Sonam, Kramer, Melissa, Russo, Suzanne, Naik, Payal, Arun, Gayatri, Brophy, Kyle, Andrews, Peter, Fan, Cheng, Perou, Charles M, Preall, Jonathan, Ha, Taehoon, Plenker, Dennis, Tuveson, David A, Rishi, Arvind, Wilkinson, John E, McCombie, W Richard, Kostroff, Karen, Spector, David L (February 2022) Patient-derived triple-negative breast cancer organoids provide robust model systems that recapitulate tumor-intrinsic characteristics. Cancer Research. ISSN 0008-5472

Bianchi, C., Sellke, F. W., Del Vecchio, R. L., Tonks, N. K., Neel, B. G. (April 1999) Receptor-type protein-tyrosine phosphatase mu is expressed in specific vascular endothelial beds in vivo. Experimental Cell Research, 248 (1). pp. 329-338. ISSN 0014-4827

Biasci, D., Smoragiewicz, M., Connell, C. M., Wang, Z., Gao, Y., Thaventhiran, J. E. D., Basu, B., Magiera, L., Johnson, T. I., Bax, L., Gopinathan, A., Isherwood, C., Gallagher, F. A., Pawula, M., Hudecova, I., Gale, D., Rosenfeld, N., Barmpounakis, P., Popa, E. C., Brais, R., Godfrey, E., Mir, F., Richards, F. M., Fearon, D. T., Janowitz, T., Jodrell, D. I. (November 2020) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. Proc Natl Acad Sci U S A, 117 (46). pp. 28960-28970. ISSN 0027-8424 (Print)0027-8424

Bodineau, Clément, Tomé, Mercedes, Courtois, Sarah, Costa, Ana SH, Sciacovelli, Marco, Rousseau, Benoit, Richard, Elodie, Vacher, Pierre, Parejo-Pérez, Carlos, Bessede, Emilie, Varon, Christine, Soubeyran, Pierre, Frezza, Christian, Murdoch, Piedad Del Socorro, Villar, Victor H, Durán, Raúl V (August 2021) Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis. Nature Communications, 12 (1). p. 4814. ISSN 2041-1723

Bonham, ChristopherA, Mandati, Vinay, Singh, RakeshK, Pappin, DarrylJ, Tonks, NicholasK (March 2023) Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks. Journal of Biological Chemistry. p. 104582. ISSN 0021-9258

Boutchueng-Djidjou, M., Belleau, P., Bilodeau, N., Fortier, S., Bourassa, S., Droit, A., Elowe, S., Faure, R. L. (October 2018) A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes. PLoS One, 13 (10). e0205180. ISSN 1932-6203

Boyer, M. J., Gutmann, D. H., Collins, F. S., Bar-Sagi, D. (February 1994) Crosslinking of the surface immunoglobulin receptor in B lymphocytes induces a redistribution of neurofibromin but not p120-GAP. Oncogene, 9 (2). pp. 349-57. ISSN 0950-9232 (Print)

Brancolini, Claudio, Lazarevic, Dean, Rodriguez, Joe, Schneider, Claudio (November 1997) Dismantling Cell-Cell Contacts during Apoptosis Is Coupled to a Caspase-dependent Proteolytic Cleavage of beta -Catenin. Journal of Cell Biology, 139 (3). pp. 759-771. ISSN 0021-9525

Broderick, K. E., MacPherson, M. R., Regulski, M., Tully, T., Dow, J. A. T., Davies, S. A. (November 2003) Interactions between epithelial nitric oxide signaling and phosphodiesterase activity in Drosophila. American Journal of Physiology-Cell Physiology, 285 (5). C1207-C1218. ISSN 0363-6143

Brägelmann, Johannes, Lorenz, Carina, Borchmann, Sven, Nishii, Kazuya, Wegner, Julia, Meder, Lydia, Ostendorp, Jenny, Ast, David F, Heimsoeth, Alena, Nakasuka, Takamasa, Hirabae, Atsuko, Okawa, Sachi, Dammert, Marcel A, Plenker, Dennis, Klein, Sebastian, Lohneis, Philipp, Gu, Jianing, Godfrey, Laura K, Forster, Jan, Trajkovic-Arsic, Marija, Zillinger, Thomas, Haarmann, Mareike, Quaas, Alexander, Lennartz, Stefanie, Schmiel, Marcel, D'Rozario, Joshua, Thomas, Emily S, Li, Henry, Schmitt, Clemens A, George, Julie, Thomas, Roman K, von Karstedt, Silvia, Hartmann, Gunther, Büttner, Reinhard, Ullrich, Roland T, Siveke, Jens T, Ohashi, Kadoaki, Schlee, Martin, Sos, Martin L (September 2021) MAPK-pathway inhibition mediates inflammatory reprogramming and sensitizes tumors to targeted activation of innate immunity sensor RIG-I. Nature Communications, 12 (1). p. 5505. ISSN 2041-1723

C

Cable, Jennifer, Heard, Edith, Hirose, Tetsuro, Prasanth, Kannanganattu V, Chen, Ling-Ling, Henninger, Jonathan E, Quinodoz, Sofia A, Spector, David L, Diermeier, Sarah D, Porman, Allison M, Kumar, Dhiraj, Feinberg, Mark W, Shen, Xiaohua, Unfried, Juan Pablo, Johnson, Rory, Chen, Chun-Kan, Wilusz, Jeremy E, Lempradl, Adelheid, McGeary, Sean E, Wahba, Lamia, Pyle, Anna Marie, Hargrove, Amanda E, Simon, Matthew D, Marcia, Marco, Przanowska, Róża K, Chang, Howard Y, Jaffrey, Samie R, Contreras, Lydia M, Chen, Qi, Shi, Junchao, Mendell, Joshua T, He, Lin, Song, Erwei, Rinn, John L, Lalwani, Mukesh Kumar, Kalem, Murat Can, Chuong, Edward B, Maquat, Lynne E, Liu, Xuhang (November 2021) Noncoding RNAs: biology and applications-a Keystone Symposia report. Annals of the New York Academy of Sciences. ISSN 0077-8923

Chen, R. A., Michaeli, T., Van Aelst, L., Ballester, R. (April 2000) A role for the noncatalytic N terminus in the function of Cdc25, a Saccharomyces cerevisiae Ras-guanine nucleotide exchange factor. Genetics, 154 (4). pp. 1473-1484. ISSN 0016-6731

Cheng, Derek K, Oni, Tobiloba E, Thalappillil, Jennifer S, Park, Youngkyu, Ting, Hsiu-Chi, Alagesan, Brinda, Prasad, Nadia V, Addison, Kenneth, Rivera, Keith D, Pappin, Darryl J, Van Aelst, Linda, Tuveson, David A (May 2021) Oncogenic KRAS engages an RSK1/NF1 pathway to inhibit wild-type RAS signaling in pancreatic cancer. Proceedings of the National Academy of Sciences of USA, 118 (21). e2016904118-e2016904118. ISSN 0027-8424

Cifani, Paolo, Kentsis, Alex (October 2022) Quantitative Cell Proteomic Atlas: Pathway-Scale Targeted Mass Spectrometry for High-Resolution Functional Profiling of Cell Signaling. Journal of Proteome Research, 21 (10). pp. 2535-2544. ISSN 1535-3893

Conklin, D. S., Galaktionov, K., Beach, D. (August 1995) 14-3-3 proteins associate with cdc25 phosphatases. Proc Natl Acad Sci U S A, 92 (17). pp. 7892-6. ISSN 0027-8424 (Print)

Cook, N., Basu, B., Smith, D. M., Gopinathan, A., Evans, J., Steward, W. P., Palmer, D., Propper, D., Venugopal, B., Hategan, M., Anthoney, D. A., Hampson, L. V., Nebozhyn, M., Tuveson, D., Farmer-Hall, H., Turner, H., McLeod, R., Halford, S., Jodrell, D. (March 2018) A phase I trial of the gamma-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma. Br J Cancer, 118 (6). pp. 793-801. ISSN 0007-0920

Curran, T., Rauscher, F. J., Cohen, D. R., Franza, B. R. (May 1988) Beyond the 2nd Messenger - Oncogenes and Transcription Factors. Cold Spring Harbor Symposia on Quantitative Biology, 53. pp. 769-777. ISSN 0091-7451

D

Dasgupta, A., Shukla, S.K., Vernucci, E., King, R.J., Abrego, J., Mulder, S.E., Mullen, N.J., Graves, G., Buettner, K., Thakur, R., Murthy, D., Attri, K.S., Wang, D., Chaika, N.V., Pacheco, C.G., Rai, I., Engle, D. D., Grandgenett, P. M., Punsoni, M., Reames, B.N., Teoh-Fitzgerald, M., Oberley-Deegan, R., Yu, F., Klute, K.A., Hollingsworth, M.A., Zimmerman, M.C., Mehla, K., Sadoshima, J., Tuveson, D. A., Singh, P.K. (July 2020) SIRT1-NOX4 Signaling Axis Regulates Cancer Cachexia. J Exp Med, 217 (7). e20190745. ISSN 0022-1007

Davies, C. C., Harvey, E., McMahon, R. F. T., Finegan, K. G., Connor, F., Davis, R. J., Tuveson, D. A., Tournier, C. (April 2014) Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma. Cancer Research, 74 (12). pp. 3344-3356. ISSN 15387445

Demerec, Milislav, Goldman, Irving, Lahr, Ernest L. (1958) Genetic recombination by transduction in Salmonella. In: Cold Spring Harbor Symposia on Quantitative Biology XXIII: Exchange of genetic material : mechanisms and consequences, Cold Spring Harbor, NY.

Dent, P., Booth, L., Roberts, J. L., Liu, J., Poklepovic, A., Lalani, A. S., Tuveson, D., Martinez, J., Hancock, J. F. (June 2019) Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. Oncogene. ISSN 0950-9232

Dong, Ao, He, Kaikai, Dudok, Barna, Farrell, Jordan S, Guan, Wuqiang, Liput, Daniel J, Puhl, Henry L, Cai, Ruyi, Wang, Huan, Duan, Jiali, Albarran, Eddy, Ding, Jun, Lovinger, David M, Li, Bo, Soltesz, Ivan, Li, Yulong (November 2021) A fluorescent sensor for spatiotemporally resolved imaging of endocannabinoid dynamics in vivo. Nature Biotechnology. ISSN 1087-0156

Dynan, W. S., Gilman, M. Z. (May 1993) Transcriptional Control and Signal Transduction - of Soap-Opera and Reductionism. Trends Genet, 9 (5). pp. 154-156. ISSN 0168-9525

F

Fee, M. S., Mitra, P. P., Kleinfeld, D. (November 1996) Automatic sorting of multiple unit neuronal signals in the presence of anisotropic and non-Gaussian variability. Journal of Neuroscience Methods, 69 (2). pp. 175-188. ISSN 0165-0270

Ferro, Austin, Auguste, Yohan SS, Cheadle, Lucas (2021) Microglia, Cytokines, and Neural Activity: Unexpected Interactions in Brain Development and Function. Frontiers in Immunology, 12. p. 703527. ISSN 1664-3224

Fisher, M. L., Balinth, S., Mills, A. A. (September 2020) p63-related signaling at a glance. J Cell Sci, 133 (17). ISSN 0021-9533 (Print)0021-9533

G

Galaktionov, K., Jessus, C., Beach, D. (May 1995) Raf1 interaction with Cdc25 phosphatase ties mitogenic signal transduction to cell cycle activation. Genes Dev, 9 (9). pp. 1046-58. ISSN 0890-9369 (Print)

Gaudinier, A., Rodriguez-Medina, J., Zhang, L., Olson, A., Liseron-Monfils, C., Bagman, A. M., Foret, J., Abbitt, S., Tang, M., Li, B., Runcie, D. E., Kliebenstein, D. J., Shen, B., Frank, M. J., Ware, D., Brady, S. M. (October 2018) Transcriptional regulation of nitrogen-associated metabolism and growth. Nature, 563 (7730). pp. 259-264. ISSN 0028-0836

Gaudino, S. J., Beaupre, M., Lin, X., Joshi, P., Rathi, S., McLaughlin, P. A., Kempen, C., Mehta, N., Eskiocak, O., Yueh, B., Blumberg, R. S., van der Velden, A. W. M., Shroyer, K. R., Bialkowska, A. B., Beyaz, S., Kumar, P. (October 2020) IL-22 receptor signaling in Paneth cells is critical for their maturation, microbiota colonization, Th17-related immune responses, and anti-Salmonella immunity. Mucosal Immunol. ISSN 1933-0219

Ge, Eva J, Bush, Ashley I, Casini, Angela, Cobine, Paul A, Cross, Justin R, DeNicola, Gina M, Dou, Q Ping, Franz, Katherine J, Gohil, Vishal M, Gupta, Sanjeev, Kaler, Stephen G, Lutsenko, Svetlana, Mittal, Vivek, Petris, Michael J, Polishchuk, Roman, Ralle, Martina, Schilsky, Michael L, Tonks, Nicholas K, Vahdat, Linda T, Van Aelst, Linda, Xi, Dan, Yuan, Peng, Brady, Donita C, Chang, Christopher J (November 2021) Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews Cancer. ISSN 1474-175X

Gilman, M., Alexandre, C., Attar, R., Grueneberg, D., Lee, G., Natesan, S., Ryan, A., Sadowski, H., Simon, K. (January 1993) Serum Response Factor-Homeodomain Complexes and the Specificity of Nuclear Signal Transduction. Journal of Cellular Biochemistry, 53 (17B). p. 59. ISSN 0730-2312

Grueneberg, D. A., Simon, K. J., Brennan, K., Gilman, M. (June 1995) Sequence-specific targeting of nuclear signal transduction pathways by homeodomain proteins. Mol Cell Biol, 15 (6). pp. 3318-26. ISSN 0270-7306 (Print)

Gunner, G., Cheadle, L., Johnson, K. M., Ayata, P., Badimon, A., Mondo, E., Nagy, M. A., Liu, L., Bemiller, S. M., Kim, K. W., Lira, S. A., Lamb, B. T., Tapper, A. R., Ransohoff, R. M., Greenberg, M. E., Schaefer, A., Schafer, D. P. (July 2019) Sensory lesioning induces microglial synapse elimination via ADAM10 and fractalkine signaling. Nat Neurosci, 22 (7). pp. 1075-1088. ISSN 1097-6256 (Print)1097-6256

Gutch, M. J., Flint, A. J., Keller, J., Tonks, N. K., Hengartner, M. O. (February 1998) The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development. Genes & Development, 12 (4). pp. 571-585. ISSN 0890-9369

H

Hanasoge Somasundara, Amritha Varshini, Moss, Matthew A, Feigman, Mary J, Chen, Chen, Cyrill, Samantha L, Ciccone, Michael F, Trousdell, Marygrace C, Vollbrecht, Macy, Li, Siran, Kendall, Jude, Beyaz, Semir, Wilkinson, John E, Dos Santos, Camila O (December 2021) Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis. Cell Reports, 37 (10). p. 110099. ISSN 2211-1247

Hoeppner, D. J., Hengartner, M. O., Fisher, D. E. (March 1996) Programmed cell death: from development to disease. Meeting report. Biochimica et Biophysica Acta - Reviews on Cancer, 1242 (3). pp. 217-20. ISSN 0006-3002 (Print)

Hrvatin, S., Hochbaum, D. R., Nagy, M. A., Cicconet, M., Robertson, K., Cheadle, L., Zilionis, R., Ratner, A., Borges-Monroy, R., Klein, A. M., Sabatini, B. L., Greenberg, M. E. (January 2018) Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex. Nat Neurosci, 21 (1). pp. 120-129. ISSN 1097-6256 (Print)1097-6256

Hsu, Y. B., Huang, C. F., Lin, K. T., Kuo, Y. L., Lan, M. C., Lan, M. Y. (June 2019) Podoplanin, a Potential Therapeutic Target for Nasopharyngeal Carcinoma. Biomed Res Int, 2019. p. 7457013.

Hu, Tuo, Shukla, Surendra K, Vernucci, Enza, He, Chunbo, Wang, Dezhen, King, Ryan J, Jha, Kanupriya, Siddhanta, Kasturi, Mullen, Nicholas J, Attri, Kuldeep S, Murthy, Divya, Chaika, Nina V, Thakur, Ravi, Mulder, Scott E, Pacheco, Camila G, Fu, Xiao, High, Robin R, Yu, Fang, Lazenby, Audrey, Steegborn, Clemens, Lan, Ping, Mehla, Kamiya, Rotili, Dante, Chaudhary, Sarika, Valente, Sergio, Tafani, Marco, Mai, Antonello, Auwerx, Johan, Verdin, Eric, Tuveson, David, Singh, Pankaj K (July 2021) Metabolic Rewiring by Loss of Sirt5 Promotes Kras-induced Pancreatic Cancer Progression. Gastroenterology. ISSN 0016-5085

Huang, T. H., Wu, A. T. H., Cheng, T. S., Lin, K. T., Lai, C. J., Hsieh, H. W., Chang, P. M., Wu, C. W., Huang, C. F., Chen, K. Y. (October 2019) In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non-small-cell lung cancer. J Cell Mol Med. ISSN 1582-1838

Huang, T. H., Wu, A. T. H., Cheng, T. S., Lin, K. T., Lai, C. J., Hsieh, H. W., Chang, P. M. H., Wu, C. W., Huang, C. Y. F., Chen, K. Y. (December 2019) In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non–small-cell lung cancer. Journal of Cellular and Molecular Medicine, 23 (12). pp. 8184-8195. ISSN 15821838 (ISSN)

J

Je, B. I., Xu, F., Wu, Q., Liu, L., Meeley, R., Gallagher, J. P., Corcilius, L., Payne, R. J., Bartlett, M. E., Jackson, D. (March 2018) The CLAVATA receptor FASCIATED EAR2 responds to distinct CLE peptides by signaling through two downstream effectors. Elife, 7. ISSN 2050-084x

Jiao, Y., Lee, Y. K., Gladman, N., Chopra, R., Christensen, S. A., Regulski, M., Burow, G., Hayes, C., Burke, J., Ware, D., Xin, Z. (February 2018) MSD1 regulates pedicellate spikelet fertility in sorghum through the jasmonic acid pathway. Nat Commun, 9 (1). p. 822. ISSN 2041-1723

Johnson, L. N., Barford, D. (January 1993) The Effects of Phosphorylation on the Structure and Function of Proteins. Annual Review of Biophysics and Biomolecular Structure, 22. pp. 199-232. ISSN 1056-8700

K

Kaiserli, E., Paldi, K., O'Donnell, L., Batalov, O., Pedmale, U. V., Nusinow, D. A., Kay, S. A., Chory, J. (November 2015) Integration of Light and Photoperiodic Signaling in Transcriptional Nuclear Foci. Dev Cell, 35 (3). pp. 311-21. ISSN 1534-5807

Kitagawa, M., Balkunde, R., Bui, H., Jackson, D. (August 2019) An Aminoacyl tRNA Synthetase, OKI1, Is Required for Proper Shoot Meristem Size in Arabidopsis. Plant Cell Physiol, 60 (11). pp. 2597-2608. ISSN 0032-0781

Kressel, A. M., Tsaava, T., Levine, Y. A., Chang, E. H., Addorisio, M. E., Chang, Q., Burbach, B. J., Carnevale, D., Lembo, G., Zador, A. M., Andersson, U., Pavlov, V. A., Chavan, S. S., Tracey, K. J. (November 2020) Identification of a brainstem locus that inhibits tumor necrosis factor. Proc Natl Acad Sci U S A, 117 (47). pp. 29803-29810. ISSN 0027-8424 (Print)0027-8424

L

Lee, M. F., Trotman, L. C. (December 2019) PTEN: Bridging Endocytosis and Signaling. Cold Spring Harb Perspect Med. ISSN 2157-1422

Lewis, P. M., Dunn, M. P., McMahon, J. A., Logan, M., Martin, J. F., St-Jacques, B., McMahon, A. P. (June 2001) Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell, 105 (5). pp. 599-612. ISSN 0092-8674 (Print)0092-8674

Liao, S. C., Hsu, H. W., Chuang, K. L., Huang, Z. Y., Lin, K. T., Hsu, W. H., Chang, K. H., Huang, C. F., Su, C. L. (June 2019) Using the Pleiotropic Characteristics of Curcumin to Validate the Potential Application of a Novel Gene Expression Screening Platform. Nutrients, 11 (6). ISSN 2072-6643

Lisman, J., Malenka, R. C., Nicoll, R. A., Malinow, R. (June 1997) Learning mechanisms: the case for CaM-KII. Science, 276 (5321). pp. 2001-2.

Liu, P. H., Shah, R. B., Li, Y., Arora, A., Ung, P. M., Raman, R., Gorbatenko, A., Kozono, S., Zhou, X. Z., Brechin, V., Barbaro, J. M., Thompson, R., White, R. M., Aguirre-Ghiso, J. A., Heymach, J. V., Lu, K. P., Silva, J. M., Panageas, K. S., Schlessinger, A., Maki, R. G., Skinner, H. D., de Stanchina, E., Sidi, S. (January 2019) An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy. Nat Cell Biol, 21 (2). pp. 203-213. ISSN 1465-7392

Liu, Q. A., Hengartner, M. O. (June 1998) Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans. Cell, 93 (6). pp. 961-72. ISSN 0092-8674 (Print)

Liu, Lei, Gallagher, Joseph, Arevalo, Edgar Demesa, Chen, Richelle, Skopelitis, Tara, Wu, Qingyu, Bartlett, Madelaine, Jackson, David (March 2021) Enhancing grain-yield-related traits by CRISPR-Cas9 promoter editing of maize CLE genes. Nature Plants, 7 (3). pp. 287-294. ISSN 2055-026X

Lucas, C. L., Workman, C. J., Beyaz, S., LoCascio, S., Zhao, G., Vignali, D. A., Sykes, M. (May 2011) LAG-3, TGF-beta, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. Blood, 117 (20). pp. 5532-40. ISSN 1528-0020 (Electronic)0006-4971 (Linking)

Luo, Y., Yang, Y., Liu, M., Wang, D., Wang, F., Bi, Y., Ji, J., Li, S., Liu, Y., Chen, R., Huang, H., Wang, X., Swidnicka-Siergiejko, A. K., Janowitz, T., Beyaz, S., Wang, G., Xu, S., Bialkowska, A. B., Luo, C. K., Pin, C. L., Liang, G., Lu, X., Wu, M., Shroyer, K. R., Wolff, R. A., Plunkett, W., Ji, B., Li, Z., Li, E., Li, X., Yang, V. W., Logsdon, C. D., Abbruzzese, J. L., Lu, W. (July 2019) Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet. Gastroenterology, 157 (5). ISSN 0016-5085

Ly, M., Rentas, S., Vujovic, A., Wong, N., Moreira, S., Xu, J., Holzapfel, N., Bhatia, S., Tran, D., Minden, M. D., Draper, J. S., Hope, K. J. (September 2019) Diminished AHR signaling drives human acute myeloid leukemia stem cell maintenance. Cancer Res. ISSN 0008-5472

M

Malinauskas, Tomas, Furukawa, Hiro (May 2016) Production of Heteromeric Transmembrane Receptors with Defined Subunit Stoichiometry. Structure, 24 (5). pp. 653-655. ISSN 0969-2126

N

Navlakha, S., Gitter, A., Bar-Joseph, Z. (August 2012) A network-based approach for predicting missing pathway interactions. PLoS Comput Biol, 8 (8). e1002640. ISSN 1553-734x

Navlakha, S., Kingsford, C. (November 2010) Exploring biological network dynamics with ensembles of graph partitions. Pac Symp Biocomput. pp. 166-177. ISSN 2335-6928

Nedivi, E., Wu, G. Y., Cline, H. T. (September 1998) Promotion of dendritic growth by CPG15, an activity-induced signaling molecule. Science, 281 (5384). pp. 1863-6. ISSN 0036-8075 (Print)

Nowak, D. G., Katsenelson, K. C., Watrud, K. E., Chen, M., Mathew, G., D'Andrea, V. D., Lee, M. F., Swamynathan, M. M., Casanova-Salas, I., Jibilian, M. C., Buckholtz, C. L., Ambrico, A. J., Pan, C. H., Wilkinson, J. E., Newton, A. C., Trotman, L. C. (May 2019) The PHLPP2 phosphatase is a druggable driver of prostate cancer progression. J Cell Biol, 218 (6). pp. 1943-1957. ISSN 0021-9525

P

Palmer, R. H., Schonwasser, D. C., Rahman, D., Pappin, D. J., Herget, T., Parker, P. J. (January 1996) PRK1 phosphorylates MARCKS at the PKC sites: serine 152, serine 156 and serine 163. Febs Letters, 378 (3). pp. 281-5. ISSN 0014-5793

Pedmale, U. V., Liscum, E. (July 2007) Regulation of phototropic signaling in Arabidopsis via phosphorylation state changes in the phototropin 1-interacting protein NPH3. J Biol Chem, 282 (27). pp. 19992-20001. ISSN 0021-9258 (Print)0021-9258

Polyanskaya, Sofya A, Moreno, Rosamaria Y, Lu, Bin, Feng, Ruopeng, Yao, Yu, Irani, Seema, Klingbeil, Olaf, Yang, Zhaolin, Wei, Yiliang, Demerdash, Osama E, Benjamin, Lukas A, Weiss, Mitchell J, Zhang, Yan Jessie, Vakoc, Christopher R (January 2022) SCP4-STK35/PDIK1L complex is a dual phospho-catalytic signaling dependency in acute myeloid leukemia. Cell Reports, 38 (2). p. 110233. ISSN 2211-1247

Ponz-Sarvise, M., Corbo, V., Tiriac, H., Engle, D. D., Frese, K. K., Oni, T. E., Hwang, C. I., Ohlund, D., Chio, I. I. C., Baker, L. A., Filippini, D., Wright, K., Bapiro, T. E., Huang, P. S., Smith, P. D., Yu, K. H., Jodrell, D. I., Park, Y., Tuveson, D. A. (September 2019) Identification of Resistance Pathways Specific to Malignancy Using Organoid Models of Pancreatic Cancer. Clin Cancer Res, 25 (22). pp. 6742-6755. ISSN 1078-0432 (Print)1078-0432

Q

Qian, Zhe, Song, Dongyan, Ipsaro, Jonathan J, Bautista, Carmelita, Joshua-Tor, Leemor, Yeh, Johannes T-H, Tonks, Nicholas K (September 2023) Manipulating PTPRD function with ectodomain antibodies. Genes and Development. ISSN 0890-9369

R

Ramesh, M., Krishnan, N., Muthuswamy, S. K., Tonks, N. K. (April 2015) A Novel Phosphatidic Acid-Protein Tyrosine Phosphatase D2 Axis is Essential for ERBB2 Signaling in Mammary Epithelial Cells. Journal of Biological Chemistry, 290 (15). pp. 9646-9659. ISSN 0021-9258

Ren, Zuen, Liang, Huizhi, Galbo, Phillip M, Dharmaratne, Malindrie, Kulkarni, Ameya S, Fard, Atefeh Taherian, Aoun, Marie Louise, Martinez-Lopez, Nuria, Suyama, Kimita, Benard, Outhiriaradjou, Zheng, Wei, Liu, Yang, Albanese, Joseph, Zheng, Deyou, Mar, Jessica C, Singh, Rajat, Prystowsky, Michael B, Norton, Larry, Hazan, Rachel B (February 2022) Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer. Proceedings of the National Academy of Sciences of USA, 119 (8). e2107266119-e2107266119. ISSN 0027-8424

Rey-Suarez, Ivan, Wheatley, Brittany A, Koo, Peter, Bhanja, Anshuman, Shu, Zhou, Mochrie, Simon, Song, Wenxia, Shroff, Hari, Upadhyaya, Arpita (January 2020) WASP family proteins regulate the mobility of the B cell receptor during signaling activation. Nature Communications, 11 (1). p. 439. ISSN 2041-1723

Riabowol, K. T., Gilman, M. Z., Feramisco, J. R. (June 1988) Microinjection of the catalytic subunit of cAMP-dependent protein kinase induces expression of the c-fos gene. Cold Spring Harb Symp Quant Biol, 53 Pt . pp. 85-90. ISSN 1943-4456

Rodriguez-Leal, D., Xu, C., Kwon, C. T., Soyars, C., Demesa-Arevalo, E., Man, J., Liu, L., Lemmon, Z. H., Jones, D. S., Van Eck, J., Jackson, D. P., Bartlett, M. E., Nimchuk, Z. L., Lippman, Z. B. (April 2019) Evolution of buffering in a genetic circuit controlling plant stem cell proliferation. Nat Genet, 51 (5). pp. 786-792. ISSN 1061-4036

Ryan, W. A., Franza, B. R., Gilman, M. Z. (June 1989) Two distinct cellular phosphoproteins bind to the c-fos serum response element. Embo J, 8 (6). pp. 1785-92. ISSN 0261-4189

S

Sadowski, H. B., Shuai, K., Darnell, J. E., Gilman, M. Z. (September 1993) A common nuclear signal transduction pathway activated by growth factor and cytokine receptors. Science, 261 (5129). pp. 1739-44. ISSN 0036-8075 (Print)

Sadowski, Henry B., Gilman, Michael Z. (March 1993) Cell-free activation of a DNA-binding protein by epidermal growth factor. Nature, 362 (6415). pp. 79-83.

Sahai, E., Astsaturov, I., Cukierman, E., DeNardo, D. G., Egeblad, M., Evans, R. M., Fearon, D., Greten, F. R., Hingorani, S. R., Hunter, T., Hynes, R. O., Jain, R. K., Janowitz, T., Jorgensen, C., Kimmelman, A. C., Kolonin, M. G., Maki, R. G., Powers, R. S., Pure, E., Ramirez, D. C., Scherz-Shouval, R., Sherman, M. H., Stewart, S., Tlsty, T. D., Tuveson, D. A., Watt, F. M., Weaver, V., Weeraratna, A. T., Werb, Z. (March 2020) A framework for advancing our understanding of cancer-associated fibroblasts. Nat Rev Cancer, 20 (3). pp. 174-186. ISSN 1474-175x

Salmeron, A., Ahmad, T. B., Carlile, G. W., Pappin, D., Narsimhan, R. P., Ley, S. C. (February 1996) Activation of MEK-1 and SEK-1 by Tpl-2 proto-oncoprotein, a novel MAP kinase kinase kinase. Embo Journal, 15 (4). pp. 817-26. ISSN 0261-4189

Sever, R., Brugge, J. S. (April 2015) Signal Transduction in Cancer. Cold Spring Harbor Perspectives in Medicine, 5 (4). ISSN 19430264

Shakiba, Mojdeh, Zumbo, Paul, Espinosa-Carrasco, Gabriel, Menocal, Laura, Dündar, Friederike, Carson, Sandra E, Bruno, Emmanuel M, Sanchez-Rivera, Francisco J, Lowe, Scott W, Camara, Steven, Koche, Richard P, Reuter, Vincent P, Socci, Nicholas D, Whitlock, Benjamin, Tamzalit, Fella, Huse, Morgan, Hellmann, Matthew D, Wells, Daniel K, Defranoux, Nadine A, Betel, Doron, Philip, Mary, Schietinger, Andrea (February 2022) TCR signal strength defines distinct mechanisms of T cell dysfunction and cancer evasion. Journal of Experimental Medicine, 219 (2). ISSN 0022-1007

Shual, K., Ziemiecki, A., Wilks, A. F., Harpur, A. G., Sadowski, H. B., Gilman, M. Z., Darnell, J. E. (December 1993) Polypeptide Signaling to the Nucleus through Tyrosine Phosphorylation of Jak and Stat Proteins. Nature, 366 (6455). pp. 580-583. ISSN 0028-0836

Steele, Nina G, Biffi, Giulia, Kemp, Samantha B, Zhang, Yaqing, Drouillard, Donovan, Syu, LiJyun, Hao, Yuan, Oni, Tobiloba E, Brosnan, Erin, Elyada, Ela, Doshi, Abhishek, Hansma, Christa, Espinoza, Carlos, Abbas, Ahmed, The, Stephanie, Irizarry-Negron, Valerie, Halbrook, Christopher J, Franks, Nicole E, Hoffman, Megan T, Brown, Kristee, Carpenter, Eileen S, Nwosu, Zeribe C, Johnson, Craig, Lima, Fatima, Anderson, Michelle A, Park, Youngkyu, Crawford, Howard C, Lyssiotis, Costas A, Frankel, Timothy L, Rao, Arvind, Bednar, Filip, Dlugosz, Andrzej A, Preall, Jonathan B, Tuveson, David A, Allen, Benjamin L, Pasca di Magliano, Marina (April 2021) Inhibition of Hedgehog Signaling Alters Fibroblast Composition in Pancreatic Cancer. Clinical Cancer Research, 27 (7). pp. 2023-2037. ISSN 1078-0432

Sun, H., Wei, Y., Deng, H., Xiong, Q., Li, M., Lahiri, J., Fang, Y. (2014) Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel. Scientific Reports, 4. p. 4934. ISSN 20452322 (ISSN)

T

Tabaska, J. E., Zhang, M. Q. (April 1999) Detection of polyadenylation signals in human DNA sequences. Gene, 231 (1-2). pp. 77-86. ISSN 0378-1119 (Print)

Thome, J., Duman, R. S., Henn, F. A. (July 2002) Molecular aspects of antidepressive therapy. Transsynaptic effects on signal transduction, gene expression and neuronal plasticity. Nervenarzt, 73 (7). pp. 595-9. ISSN 0028-2804 (Print)0028-2804 (Linking)

Tonks, Nicholas K (April 2023) Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow. IUBMB Life, 75 (4). pp. 337-352. ISSN 1521-6543

Tonks, N. K. (July 2003) PTP1B: From the sidelines to the front lines! Febs Letters, 546 (1). pp. 140-148. ISSN 0014-5793

Tonks, N. K. (January 2013) Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction. Febs Journal, 280 (2). pp. 346-378. ISSN 1742464X

Tonks, N. K. (1996) Protein tyrosine phosphatases and the control of cellular signaling responses. Advances in Pharmacology, 36. pp. 91-119. ISSN 1054-3589 (Print)

Tonks, N. K., Flint, A. J., Gebbink, M. F., Sun, H., Yang, Q. (1993) Signal transduction and protein tyrosine dephosphorylation. Adv Second Messenger Phosphoprotein Res, 28. pp. 203-10. ISSN 1040-7952 (Print)

Tyers, M., Futcher, B. (March 1994) Far1 and Fus3 Link the Mating Pheromone Signal-Transduction Pathway to 3 G(1)-Phase Cdc28 Kinase Complexes. Molecular and Cellular Biology, 14 (3). p. 2222. ISSN 0270-7306

V

Van Aelst, L., D'Souza-Schorey, C. (September 1997) Rho GTPases and signaling networks. Genes and Development, 11 (18). pp. 2295-322. ISSN 08909369 (ISSN)

Van Aelst, L., Hohmann, S., Bulaya, B., Dekoning, W., Sierkstr, L., Neves, M. J., Luyten, K., Alijo, R., Ramos, J., Coccetti, P., Martegani, E., Demagalhaesrocha, N. M., Brandao, R. L., Vandijck, P., Vanhalewyn, M., Durnez, P., Jans, A. W. H., Thevelein, J. M. (May 1993) Molecular-Cloning of a Gene Involved in Glucose Sensing in the Yeast Saccharomyces-Cerevisiae. Molecular Microbiology, 8 (5). pp. 927-943. ISSN 0950-382X

Van Aelst, L., Joneson, T., Bar-Sagi, D. (August 1996) Identification of a novel Rac1-interacting protein involved in membrane ruffling. Embo Journal, 15 (15). pp. 3778-86. ISSN 0261-4189

Venkatasubramani, J.P., Subramanyam, P., Pal, R., Reddy, B.K., Srinivasan, D.J., Chattarji, S., Iossifov, I., Klann, E., Bhattacharya, S. (March 2020) N-terminal Variant Asp14Asn of the Human p70 S6 Kinase 1 Enhances Translational Signaling Causing Different Effects in Developing and Mature Neuronal Cells. Neurobiology of Learning and Memory, 171 (107203). ISSN 1074-7427

Vignais, M. L., Sadowski, H. B., Watling, D., Rogers, N. C., Gilman, M. (April 1996) Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins. Molecular and Cellular Biology, 16 (4). pp. 1759-69. ISSN 0270-7306

W

Walker, W. H., Borniger, J. C. (June 2019) Molecular Mechanisms of Cancer-Induced Sleep Disruption. Int J Mol Sci, 20 (11). ISSN 1422-0067

Weiss, C. A., White, E., Huang, H., Ma, H. (May 1997) The G protein alpha subunit (GP alpha1) is associated with the ER and the plasma membrane in meristematic cells of Arabidopsis and cauliflower. Febs Letters, 407 (3). pp. 361-7. ISSN 0014-5793

Wright, N. J., Zhong, Y. (January 1998) Serotonin-sensitive leakage channel in Drosophila central neurons. J Neurobiol, 34 (1). pp. 83-95. ISSN 0022-3034 (Print)

Wu, Q., Xu, F., Liu, L., Char, S. N., Ding, Y., Je, B. I., Schmelz, E., Yang, B., Jackson, D. (December 2019) The maize heterotrimeric G protein beta subunit controls shoot meristem development and immune responses. Proc Natl Acad Sci U S A, 117 (3). pp. 1799-1805. ISSN 0027-8424 (Public Dataset)

Wu, Yue, Berisha, Adrian, Borniger, Jeremy C (July 2022) Neuropeptides in Cancer: Friend and Foe? Advanced Biology. e2200111. ISSN 2701-0198

Y

Yaeger, Rona, Mezzadra, Riccardo, Sinopoli, Jenna, Bian, Yu, Marasco, Michelangelo, Kaplun, Esther, Gao, Yijun, Zhao, HuiYong, Paula, Arnaud Da Cruz, Zhu, Yingjie, Perez, Almudena Chaves, Chadalavada, Kalyani, Tse, Edison, Chowdhry, Sudhir, Bowker, Sydney, Chang, Qing, Qeriqi, Besnik, Weigelt, Britta, Nanjangud, Gouri J, Berger, Michael F, Der-Torossian, Hirak, Anderes, Kenna, Socci, Nicholas D, Shia, Jinru, Riely, Gregory J, Murciano-Goroff, Yonina R, Li, Bob T, Christensen, James G, Reis-Filho, Jorge S, Solit, David B, de Stanchina, Elisa, Lowe, Scott W, Rosen, Neal, Misale, Sandra (January 2023) Molecular Characterization of Acquired Resistance to KRASG12C-EGFR Inhibition in Colorectal Cancer. Cancer Discovery, 13 (1). pp. 41-55. ISSN 2159-8274

Yang, Huan, Lundbäck, Peter, Ottosson, Lars, Erlandsson-Harris, Helena, Venereau, Emilie, Bianchi, Marco E, Al-Abed, Yousef, Andersson, Ulf, Tracey, Kevin J (June 2021) Redox modifications of cysteine residues regulate the cytokine activity of HMGB1. Molecular Medicine, 27 (1). p. 58. ISSN 1076-1551