Integration of Light and Photoperiodic Signaling in Transcriptional Nuclear Foci

Kaiserli, E., Paldi, K., O'Donnell, L., Batalov, O., Pedmale, U. V., Nusinow, D. A., Kay, S. A., Chory, J. (November 2015) Integration of Light and Photoperiodic Signaling in Transcriptional Nuclear Foci. Dev Cell, 35 (3). pp. 311-21. ISSN 1534-5807

DOI: 10.1016/j.devcel.2015.10.008


Light regulates major plant developmental transitions by orchestrating a series of nuclear events. This study uncovers the molecular function of the natural variant, TZP (Tandem Zinc-finger-Plus3), as a signal integrator of light and photoperiodic pathways in transcriptional nuclear foci. We report that TZP acts as a positive regulator of photoperiodic flowering via physical interactions with the red-light receptor phytochrome B (phyB). We demonstrate that TZP localizes in dynamic nuclear domains regulated by light quality and photoperiod. This study shows that phyB is indispensable not only for localizing TZP to transcriptionally active nuclear photobodies, but also for recruiting TZP on the promoter of the floral inducer FLOWERING LOCUS T (FT). Our findings signify a unique transcriptional regulatory role to the highly enigmatic plant nuclear photobodies, where TZP directly activates FT gene expression and promotes flowering.

Item Type: Paper
Uncontrolled Keywords: Arabidopsis/genetics/*metabolism Arabidopsis Proteins/*metabolism Cell Nucleus/*metabolism Circadian Rhythm/*physiology Gene Expression Regulation, Plant/*physiology *Light Photoperiod Signal Transduction/genetics Transcription Factors/*metabolism Transcription, Genetic
Subjects: organism description > plant > Arabidopsis
bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transcription
organism description > plant
organs, tissues, organelles, cell types and functions > tissues types and functions > signal transduction
CSHL Authors:
Communities: CSHL labs > Pedmale lab
Depositing User: Matt Covey
Date: 9 November 2015
Date Deposited: 13 Jun 2016 16:50
Last Modified: 13 Jun 2016 16:50
PMCID: PMC4654455
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