Items where Community is "Janowitz lab"

Paper

Kwon, Young-Yon, Liang, Yanshan, Gomez-Jenkins, Maria, Ahmed, Mujmmail, Jiang, Guangru, Hsiang, Juliya, Lewis, David Y, Janowitz, Tobias, Goncalves, Marcus D, White, Eileen, Hui, Sheng (May 2025) Sustained Glucose Turnover Flux Distinguishes Cancer Cachexia from Nutrient Limitation. bioRxiv. ISSN 2692-8205 (Submitted)

Koh, Kexin, Scott, Rachel, Cespedes Feliciano, Elizabeth M, Janowitz, Tobias, Goncalves, Marcus D, White, Eileen P, Laird, Barry JA, Haase, Kerstin, Jamal-Hanjani, Mariam (April 2025) Cancer-Associated Cachexia: Bridging Clinical Findings with Mechanistic Insights in Human Studies. Cancer Discovery. OF1-OF26. ISSN 2159-8290

Zhu, Xiaoyue Aelita, Starosta, Sarah, Ferrer, Miriam, Hou, Junxiao, Chevy, Quentin, Lucantonio, Federica, Muñoz-Castañeda, Rodrigo, Zhang, Fengrui, Zang, Kaikai, Zhao, Xiang, Fiocchi, Francesca R, Bergstrom, Mason, Siebels, Aubrey A, Upin, Thomas, Wulf, Michael, Evans, Sarah, Kravitz, Alexxai V, Osten, Pavel, Janowitz, Tobias, Pignatelli, Marco, Kepecs, Adam (April 2025) A neuroimmune circuit mediates cancer cachexia-associated apathy. Science, 388 (6743). eadm8857. ISSN 0036-8075

Liu, Ying, Dantas, Ezequiel, Ferrer, Miriam, Miao, Ting, Qadiri, Mujeeb, Liu, Yifang, Comjean, Aram, Davidson, Emma E, Perrier, Tiffany, Ahmed, Tanvir, Hu, Yanhui, Goncalves, Marcus D, Janowitz, Tobias, Perrimon, Norbert (April 2025) Hepatic gluconeogenesis and PDK3 upregulation drive cancer cachexia in flies and mice. Nature Metabolism, 7 (4). pp. 823-841. ISSN 2522-5812 (Public Dataset)

Goncalves, Marcus D, Janowitz, Tobias (March 2025) Reply to: Overcoming Barriers to Cancer-Associated Cachexia Diagnosis and Management. JCO Oncology Practice. OP2500108. ISSN 2688-1527

Ibrahim, Maria, Gomez-Jenkins, Maria, Scheinfeld, Adina, Zhao, Zhengqiao, Lopes, Eduardo Cararo, Sawant, Akshada, Hu, Zhixian, Dharani, Aditya, Sun, Michael, Siddiqui, Sarah, Mirek, Emily T, Abram-Saliba, Johan, Lattime, Edmund C, Su, Xiaoyang, Janowitz, Tobias, Goncalves, Marcus D, Dunn, Steven M, Pritykin, Yuri, Anthony, Tracy G, Rabinowitz, Joshua D, White, Eileen (February 2025) Autophagy Suppresses CCL2 to Preserve Appetite and Prevent Lethal Cachexia. bioRxiv. ISSN 2692-8205 (Submitted)

Fuller, Sophia, Alexeeff, Stacey, Caan, Bette, Dasilva Goncalves, Marcus, Dunne, Richard F, Janowitz, Tobias, Jamal-Hanjani, Mariam, Sundaresan, Tilak K, Cespedes Feliciano, Elizabeth M (February 2025) Early identification of weight loss trajectories in advanced cancer and associations with survival. Journal of the National Cancer Institute. djaf030. ISSN 0027-8874

Altea-Manzano, Patricia, Decker-Farrell, Amanda, Janowitz, Tobias, Erez, Ayelet (January 2025) Metabolic interplays between the tumour and the host shape the tumour macroenvironment. Nature Reviews Cancer. ISSN 1474-175X

Goncalves, Marcus D, Dunne, Richard F, Moore, Amy C, Phillips, Wendy, Heymsfield, Steven B, Brown, Justin C, Talbert, Erin E, Janowitz, Tobias (January 2025) Call to Improve Coding of Cancer-Associated Cachexia. JCO Oncology Practice. OP2400781. ISSN 2688-1527

Swamynathan, Manojit M, Kuang, Shan, Watrud, Kaitlin E, Doherty, Mary R, Gineste, Charlotte, Mathew, Grinu, Gong, Grace Q, Cox, Hilary, Cheng, Eileen, Reiss, David, Kendall, Jude, Ghosh, Diya, Reczek, Colleen R, Zhao, Xiang, Herzka, Tali, Špokaitė, Saulė, Dessus, Antoine N, Kim, Seung Tea, Klingbeil, Olaf, Liu, Juan, Nowak, Dawid G, Alsudani, Habeeb, Wee, Tse-Luen, Park, Youngkyu, Minicozzi, Francesca, Rivera, Keith, Almeida, Ana S, Chang, Kenneth, Chakrabarty, Ram P, Wilkinson, John E, Gimotty, Phyllis A, Diermeier, Sarah D, Egeblad, Mikala, Vakoc, Christopher R, Locasale, Jason W, Chandel, Navdeep S, Janowitz, Tobias, Hicks, James B, Wigler, Michael, Pappin, Darryl J, Williams, Roger L, Cifani, Paolo, Tuveson, David A, Laporte, Jocelyn, Trotman, Lloyd C (October 2024) Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function. Science, 386 (6720). eadk9167. ISSN 0036-8075

Michalski, Kevin, Abdulla, Taha, Kleeman, Sam, Schmidl, Lars, Gómez, Ricardo, Simorowski, Noriko, Vallese, Francesca, Prüss, Harald, Heckmann, Manfred, Geis, Christian, Furukawa, Hiro (September 2024) Structural and functional mechanisms of anti-NMDAR autoimmune encephalitis. Nature Structural & Molecular Biology. ISSN 1545-9993 (Public Dataset)

Lee, Hassal, Palafox, Neal A, Janowitz, Tobias (August 2024) Inclusion of American Indian, Alaska Native, Native Hawaiian, and Pacific Islander Patients in Clinical Trial Travel Time-Reply. JAMA Oncology. ISSN 2374-2437

Boire, Adrienne, Burke, Katy, Cox, Thomas R, Guise, Theresa, Jamal-Hanjani, Mariam, Janowitz, Tobias, Kaplan, Rosandra, Lee, Rebecca, Swanton, Charles, Vander Heiden, Matthew G, Sahai, Erik (June 2024) Why do patients with cancer die? Nature Reviews Cancer. ISSN 1474-175X

Langer, Henning Tim, Ramsamooj, Shakti, Dantas, Ezequiel, Murthy, Anirudh, Ahmed, Mujmmail, Ahmed, Tanvir, Hwang, Seo-Kyoung, Grover, Rahul, Pozovskiy, Rita, Liang, Roger J, Queiroz, Andre Lima, Brown, Justin C, White, Eileen P, Janowitz, Tobias, Goncalves, Marcus D (May 2024) Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer. Acta Physiologica. e14167. ISSN 1748-1708

Dai, Enyong, Chen, Xin, Linkermann, Andreas, Jiang, Xuejun, Kang, Rui, Kagan, Valerian E, Bayir, Hülya, Yang, Wan Seok, Garcia-Saez, Ana J, Ioannou, Maria S, Janowitz, Tobias, Ran, Qitao, Gu, Wei, Gan, Boyi, Krysko, Dmitri V, Zhu, Xiaofeng, Wang, Jiayi, Krautwald, Stefan, Toyokuni, Shinya, Xie, Yangchun, Greten, Florian R, Yi, Qing, Schick, Joel, Liu, Jiao, Gabrilovich, Dmitry I, Liu, Jinbao, Zeh, Herbert J, Zhang, Donna D, Yang, Minghua, Iovanna, Juan, Kopf, Manfred, Adolph, Timon E, Chi, Jen-Tsan, Li, Changfeng, Ichijo, Hidenori, Karin, Michael, Sankaran, Vijay G, Zou, Weiping, Galluzzi, Lorenzo, Bush, Ashley I, Li, Binghui, Melino, Gerry, Baehrecke, Eric H, Lotze, Michael T, Klionsky, Daniel J, Stockwell, Brent R, Kroemer, Guido, Tang, Daolin (February 2024) A guideline on the molecular ecosystem regulating ferroptosis. Nature Cell Biology. ISSN 1465-7392

Ecker, DJ, Aiello, CD, Arron, JR, Bennett, CF, Bernard, A, Breakefield, XO, Broderick, TJ, Callier, SL, Canton, B, Chen, JS, Fishburn, CS, Garrett, B, Hecht, SM, Janowitz, T, Kliegman, M, Krainer, A, Louis, CU, Lowe, C, Sehgal, A, Tozan, Y, Tracey, KJ, Urnov, F, Wattendorf, D, Williams, TW, Zhao, X, Hayden, MR (February 2024) Opportunities and challenges for innovative and equitable healthcare. Nature Reviews Drug Discovery. ISSN 1474-1776

Wiberg, Akira, Lucey, Maria A, Kleeman, Sam, Kang, Youngjoo, Ng, Mike, Furniss, Dominic (August 2023) Genetic correlations between migraine and carpal tunnel syndrome. Plastic and Reconstructive Surgery. ISSN 0032-1052

Merrill, Joseph R, Inguscio, Alessandra, Chung, Taemoon, Demestichas, Breanna, Garcia, Libia A, Habel, Jill, Lewis, David Y, Janowitz, Tobias, Lyons, Scott K (August 2023) Sensitive, non-immunogenic in vivo imaging of cancer metastases and immunotherapy response. Cell Stress, 7 (8). pp. 59-68. ISSN 2523-0204

Kleeman, Sam O, Thakir, Tuba Mansoor, Demestichas, Breanna, Mourikis, Nicholas, Loiero, Dominik, Ferrer, Miriam, Bankier, Sean, Riazat-Kesh, Yosef JRA, Lee, Hassal, Chantzichristos, Dimitrios, Regan, Claire, Preall, Jonathan, Sinha, Sarthak, Rosin, Nicole, Yipp, Bryan, de Almeida, Luiz GN, Biernaskie, Jeff, Dufour, Antoine, Tober-Lau, Pinkus, Ruusalepp, Arno, Bjorkegren, Johan LM, Ralser, Markus, Kurth, Florian, Demichev, Vadim, Heywood, Todd, Gao, Qing, Johannsson, Gudmundur, Koelzer, Viktor H, Walker, Brian R, Meyer, Hannah V, Janowitz, Tobias (August 2023) Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy. Cell Genomics, 3 (8). p. 100347. ISSN 2666-979X

Langer, Henning Tim, Ramsamooj, Shakti, Dantas, Ezequiel, Murthy, Anirudh, Ahmed, Mujmmail, Hwang, Seo-Kyoung, Grover, Rahul, Pozovskiy, Rita, Liang, Roger J, Queiroz, Andre Lima, Brown, Justin C, White, Eileen P, Janowitz, Tobias, Goncalves, And Marcus D (August 2023) Restoring adiponectin via rosiglitazone ameliorates tissue wasting in mice with lung cancer. bioRxiv. (Submitted)

Liu, Ying, Dantas, Ezequiel, Ferrer, Miriam, Liu, Yifang, Comjean, Aram, Davidson, Emma E, Hu, Yanhui, Goncalves, Marcus D, Janowitz, Tobias, Perrimon, Norbert (May 2023) Tumor Cytokine-Induced Hepatic Gluconeogenesis Contributes to Cancer Cachexia: Insights from Full Body Single Nuclei Sequencing. bioRxiv. (Submitted)

Ferrer, Miriam, Anthony, Tracy G, Ayres, Janelle S, Biffi, Giulia, Brown, Justin C, Caan, Bette J, Cespedes Feliciano, Elizabeth M, Coll, Anthony P, Dunne, Richard F, Goncalves, Marcus D, Grethlein, Jonas, Heymsfield, Steven B, Hui, Sheng, Jamal-Hanjani, Mariam, Lam, Jie Min, Lewis, David Y, McCandlish, David, Mustian, Karen M, O'Rahilly, Stephen, Perrimon, Norbert, White, Eileen P, Janowitz, Tobias (April 2023) Cachexia: A systemic consequence of progressive, unresolved disease. Cell, 186 (9). pp. 1824-1845. ISSN 0092-8674

Lee, Hassal, Ciabatti, Ernesto, González-Rueda, Ana, Williams, Elena, Nugent, Fiona, Mookerjee, Souradip, Morgese, Fabio, Tripodi, Marco (March 2023) Combining long-term circuit mapping and network transcriptomics with SiR-N2c. Nature Methods. ISSN 1548-7091 (Public Dataset)

Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E, Kleeman, Sam O, Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Flint, Thomas R, Connell, Claire M, Lukey, Michael J, White, Eileen P, Coll, Anthony P, Venkitaraman, Ashok R, Janowitz, Tobias (February 2023) Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia. bioRxiv. (Submitted)

Mou, Haiwei, Eskiocak, Onur, Özler, Kadir A, Gorman, Megan, Yue, Junjiayu, Jin, Ying, Wang, Zhikai, Gao, Ya, Janowitz, Tobias, Meyer, Hannah V, Yu, Tianxiong, Wilkinson, John E, Kucukural, Alper, Ozata, Deniz M, Beyaz, Semir (January 2023) CRISPR-induced exon skipping of β-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer. Journal of Pathology. ISSN 0022-3417

Sun, Qingtao, van de Lisdonk, Daniëlle, Ferrer, Miriam, Gegenhuber, Bruno, Wu, Melody, Tollkuhn, Jessica, Janowitz, Tobias, Li, Bo (January 2023) Area postrema neurons mediate interleukin-6 function in cancer-associated cachexia. bioRxiv. (Unpublished)

Lee, Hassal, Bates, Alexander, Marshall, Andrea, Callier, Shawneequa, Chambwe, Nyasha, Janowitz, Tobias (2023) Analysis and optimization of equitable US cancer clinical trial center access by travel time. Journal of Clinical Oncology, 41 (16). ISSN 0732-183X

Furlan, Alessandro, Corona, Alberto, Boyle, Sara, Sharma, Radhashree, Rubino, Rachel, Habel, Jill, Gablenz, Eva Carlotta, Giovanniello, Jacqueline, Beyaz, Semir, Janowitz, Tobias, Shea, Stephen David, Li, Bo (October 2022) Neurotensin neurons in the extended amygdala control dietary choice and energy homeostasis. Nature Neuroscience. ISSN 1097-6256

Hashimoto, Taiki, Takayanagi, Daisuke, Yonemaru, Junpei, Naka, Tomoaki, Nagashima, Kengo, Yatabe, Yasushi, Shida, Dai, Hamamoto, Ryuji, Kleeman, Sam O, Leedham, Simon J, Maughan, Timothy, Takashima, Atsuo, Shiraishi, Kouya, Sekine, Shigeki (October 2022) Clinicopathological and molecular characteristics of RSPO fusion-positive colorectal cancer. British Journal of Cancer, 127 (6). pp. 1043-1050. ISSN 0007-0920

Kleeman, Sam O, Cordioli, Mattia, Timmers, Paul RHJ, Khan, Atlas, Tober-Lau, Pinkus, Kurth, Florian, Demichev, Vadim, Meyer, Hannah V, Wilson, James F, Ralser, Markus, Kiryluk, Krzysztof, Ganna, Andrea, Baillie, Kenneth, Janowitz, Tobias (October 2022) Cystatin C is associated with adverse COVID-19 outcomes in diverse populations. iScience, 25 (10). p. 105040. ISSN 2589-0042 (In Press)

Patel, B, Kleeman, SO, Neavin, D, Powell, J, Baskozos, G, Ng, M, Ahmed, WUR, Bennett, DL, Schmid, AB, Furniss, D, Wiberg, A (August 2022) Shared genetic susceptibility between trigger finger and carpal tunnel syndrome: a genome-wide association study. The Lancet Rheumatology, 4 (8). e556-e565. ISSN 2665-9913

Song, Dongyan, Adrover, Jose M, Felice, Christy, Christensen, Lisa N, He, Xue-Yan, Merrill, Joseph R, Wilkinson, John E, Janowitz, Tobias, Lyons, Scott K, Egeblad, Mikala, Tonks, Nicholas K (July 2022) PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils. JCI Insight, 7 (14). e158199. ISSN 2379-3708

Ferrer, Miriam, Janowitz, Tobias (June 2022) Training the host organism to enhance anti-cancer immunity. Cancer Cell. S1535-6108(22)00267. ISSN 1535-6108

Ahmed, Waheed-Ul-Rahman, Kleeman, Sam, Ng, Michael, Wang, Wei, Auton, Adam, 23andMe Research Team, Lee, Regent, Handa, Ashok, Zondervan, Krina T, Wiberg, Akira, Furniss, Dominic (June 2022) Genome-wide association analysis and replication in 810,625 individuals with varicose veins. Nature Communications, 13 (1). p. 3065. ISSN 2041-1723

Brennan, Christina M, Nadella, Sandeep, Zhao, Xiang, Dima, Richard J, Jordan-Martin, Nicole, Demestichas, Breanna R, Kleeman, Sam O, Ferrer, Miriam, von Gablenz, Eva Carlotta, Mourikis, Nicholas, Rubin, Michael E, Adnani, Harsha, Lee, Hassal, Ha, Taehoon, Prum, Soma, Schleicher, Cheryl B, Fox, Sharon S, Ryan, Michael G, Pili, Christina, Goldberg, Gary, Crawford, James M, Goodwin, Sara, Zhang, Xiaoyue, Preall, Jonathan B, Costa, Ana SH, Conigliaro, Joseph, Masci, Joseph R, Yang, Jie, Tuveson, David A, Tracey, Kevin J, Janowitz, Tobias (February 2022) Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial. Gut. ISSN 0017-5749

Petruzzelli, M, Ferrer, M, Schuijs, MJ, Kleeman, SO, Mourikis, N, Hall, Z, Perera, D, Raghunathan, S, Vacca, M, Gaude, E, Lukey, MJ, Jodrell, DI, Frezza, C, Wagner, EF, Venkitaraman, AR, Halim, TYF, Janowitz, T (February 2022) Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia. Cancers, 14 (4). p. 963. ISSN 2072-6694

Wang, Zhikai, Moresco, Philip, Yan, Ran, Li, Jiayun, Gao, Ya, Biasci, Daniele, Yao, Min, Pearson, Jordan, Hechtman, Jaclyn F, Janowitz, Tobias, Zaidi, Raza M, Weiss, Matthew J, Fearon, Douglas T (January 2022) Carcinomas assemble a filamentous CXCL12-keratin-19 coating that suppresses T cell-mediated immune attack. Proceedings of the National Academy of Sciences of USA, 119 (4). e2119463119-e2119463119. ISSN 0027-8424

Furlan, Alessandro, Corona, Alberto, Boyle, Sara, Sharma, Radhashree, Rubino, Rachel, Habel, Jill, Gablenz, Eva Carlotta, Giovanniello, Jacqueline, Beyaz, Semir, Janowitz, Tobias, Shea, Stephen D, Li, Bo (August 2021) Neurotensin neurons in the central extended amygdala control energy balance. bioRxiv. (Unpublished)

Kolamunnage-Dona, Ruwanthi, Berhane, Sarah, Potts, Harry, Williams, Edward H, Tanner, James, Janowitz, Tobias, Hoare, Matthew, Johnson, Philip (May 2021) Sorafenib is associated with a reduced rate of tumour growth and liver function deterioration in HCV-induced hepatocellular carcinoma. Journal of Hepatology. ISSN 0168-8278

Yang, Wen-Hsuan, Qiu, Yijian, Stamatatos, Olivia, Janowitz, Tobias, Lukey, Michael J (May 2021) Enhancing the Efficacy of Glutamine Metabolism Inhibitors in Cancer Therapy. Trends in Cancer. ISSN 2405-8033

Janowitz, Tobias, Kleeman, Sam, Vonderheide, Robert H (April 2021) Reconsidering Dexamethasone for Antiemesis when Combining Chemotherapy and Immunotherapy. The Oncologist, 26 (4). pp. 269-273. ISSN 1083-7159

Fearon, Douglas T, Janowitz, Tobias (March 2021) AMD3100/Plerixafor overcomes immune inhibition by the CXCL12-KRT19 coating on pancreatic and colorectal cancer cells. British Journal of Cancer. ISSN 0007-0920

Williams, Edward H, Flint, Thomas R, Connell, Claire M, Giglio, Daniel, Lee, Hassal, Ha, Taehoon, Gablenz, Eva, Bird, Nicholas J, Weaver, James MJ, Potts, Harry, Whitley, Cameron T, Bookman, Michael A, Lynch, Andy G, Meyer, Hannah V, Tavaré, Simon, Janowitz, Tobias (March 2021) CamGFR v2: A New Model for Estimating the Glomerular Filtration Rate from Standardized or Non-standardized Creatinine in Patients with Cancer. Clinical Cancer Research, 27 (5). pp. 1381-1390. ISSN 1078-0432

Munir, Hafsa, Jones, James O, Janowitz, Tobias, Hoffmann, Markus, Euler, Maximilien, Martins, Carla P, Welsh, Sarah J, Shields, Jacqueline D (January 2021) Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth. Nature Communications, 12 (1). p. 683. ISSN 2041-1723

Biasci, D., Smoragiewicz, M., Connell, C. M., Wang, Z., Gao, Y., Thaventhiran, J. E. D., Basu, B., Magiera, L., Johnson, T. I., Bax, L., Gopinathan, A., Isherwood, C., Gallagher, F. A., Pawula, M., Hudecova, I., Gale, D., Rosenfeld, N., Barmpounakis, P., Popa, E. C., Brais, R., Godfrey, E., Mir, F., Richards, F. M., Fearon, D. T., Janowitz, T., Jodrell, D. I. (November 2020) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. Proc Natl Acad Sci U S A, 117 (46). pp. 28960-28970. ISSN 0027-8424 (Print)0027-8424

Kleeman, Sam O, Leedham, Simon J (November 2020) Not All Wnt Activation Is Equal: Ligand-Dependent versus Ligand-Independent Wnt Activation in Colorectal Cancer. Cancers, 12 (11). pp. 1-16. ISSN 2072-6694

Weber, A. G., Chau, A. S., Egeblad, M., Barnes, B. J., Janowitz, T. (September 2020) Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series. Mol Med, 26 (1). p. 91. ISSN 1076-1551 (Print)1076-1551

Wang, Zhikai, Yan, Ran, Li, Jiayun, Gao, Ya, Moresco, Philip, Yao, Min, Hechtman, Jaclyn F, Weiss, Matthew J, Janowitz, Tobias, Fearon, Douglas T (September 2020) Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy. bioRxiv. (Unpublished)

Biasci, D., Smoragiewicz, M., Connell, C. M., Wang, Z., Gao, Y., Thaventhiran, J. E., Basu, B., Magiera, L., Johnson, I. T., Bax, L., Gopinathan, A., Isherwood, C., Gallagher, F., Pawula, M., Hudecova, I., Gale, D., Rosenfeld, N., Barmpounakis, P., Popa, E. C., Brais, R., Godfrey, E., Mir, F., Richards, F., Fearon, D. T., Janowitz, T., Jodrell, D. (July 2020) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. medRxiv. (Unpublished)

Janowitz, T., Gablenz, E., Pattinson, D., Wang, T.C., Conigliaro, J., Tracey, K., Tuveson, D. (June 2020) Famotidine Use and Quantitative Symptom Tracking for COVID-19 in Non-Hospitalised Patients: A Case Series. Gut, 69 (9). pp. 1592-1597. ISSN 1468-3288

Weber, Andrew G, Chau, Alice S, Egeblad, Mikala, Barnes, Betsy J, Janowitz, Tobias (May 2020) Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series. MedRxiv. (Unpublished)

Janowitz, T., Tuveson, D. A. (May 2020) The Era of COVID-19 and the Rise of Science Collectivism in Cancer Research. Cancer Discov, 10 (7). pp. 913-915. ISSN 2159-8274

Sahai, E., Astsaturov, I., Cukierman, E., DeNardo, D. G., Egeblad, M., Evans, R. M., Fearon, D., Greten, F. R., Hingorani, S. R., Hunter, T., Hynes, R. O., Jain, R. K., Janowitz, T., Jorgensen, C., Kimmelman, A. C., Kolonin, M. G., Maki, R. G., Powers, R. S., Pure, E., Ramirez, D. C., Scherz-Shouval, R., Sherman, M. H., Stewart, S., Tlsty, T. D., Tuveson, D. A., Watt, F. M., Weaver, V., Weeraratna, A. T., Werb, Z. (March 2020) A framework for advancing our understanding of cancer-associated fibroblasts. Nat Rev Cancer, 20 (3). pp. 174-186. ISSN 1474-175x

Connell, Claire M, Brais, Rebecca, Whitaker, Hayley, Upponi, Sara, Beh, Ian, Risdall, Jane, Corrie, Pippa, Janowitz, Tobias, Jodrell, Duncan I (January 2020) Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report. BMC Cancer, 20 (1). p. 38. ISSN 1471-2407

Munir, Hafsa, Jones, James O, Janowitz, Tobias, Martins, Carla P, Welsh, Sarah J, Shields, Jacqueline D (January 2020) Stromal Amyloid β drives Neutrophil extracellular trap formation to augment tumour growth. BioRxiv. (Unpublished)

Williams, Edward H, Connell, Claire M, Weaver, James MJ, Beh, Ian, Potts, Harry, Whitley, Cameron T, Bird, Nicholas, Al-Sayed, Tamer, Monaghan, Phillip J, Fehr, Martin, Cathomas, Richard, Bertelli, Gianfilippo, Quinton, Amy, Lewis, Paul, Shamash, Jonathan, Wilson, Peter, Dooley, Michael, Poole, Susan, Mark, Patrick B, Bookman, Michael A, Earl, Helena, Jodrell, Duncan, Tavaré, Simon, Lynch, Andy G, Janowitz, Tobias (December 2019) Multicenter Validation of the CamGFR Model for Estimated Glomerular Filtration Rate. JNCI Cancer Spectrum, 3 (4). pkz068. ISSN 2515-5091

Luo, Y., Yang, Y., Liu, M., Wang, D., Wang, F., Bi, Y., Ji, J., Li, S., Liu, Y., Chen, R., Huang, H., Wang, X., Swidnicka-Siergiejko, A. K., Janowitz, T., Beyaz, S., Wang, G., Xu, S., Bialkowska, A. B., Luo, C. K., Pin, C. L., Liang, G., Lu, X., Wu, M., Shroyer, K. R., Wolff, R. A., Plunkett, W., Ji, B., Li, Z., Li, E., Li, X., Yang, V. W., Logsdon, C. D., Abbruzzese, J. L., Lu, W. (July 2019) Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet. Gastroenterology, 157 (5). ISSN 0016-5085

Janowitz, T. (July 2018) Cancer: The Tumor-Driven Disease of the Host. Cell Metab, 28 (1). pp. 5-6. ISSN 1550-4131

Sng, C. C. T., O'Byrne, S., Prigozhin, D. M., Bauer, M. R., Harvey, J. C., Ruhle, M., Challis, B. G., Lear, S., Roberts, L. D., Workman, S., Janowitz, T., Magiera, L., Doffinger, R., Buckland, M. S., Jodrell, D. J., Semple, R. K., Wilson, T. J., Modis, Y., Thaventhiran, J. E. D. (July 2018) A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway. J Allergy Clin Immunol, 142 (1). 311-314.e6. ISSN 0091-6749

Flint, T. R., Jones, J. O., Ferrer, M., Colucci, F., Janowitz, T. (March 2018) A comparative analysis of immune privilege in pregnancy and cancer in the context of checkpoint blockade immunotherapy. Semin Oncol. ISSN 0093-7754

Connell, C. M., Raby, S. E. M., Beh, I., Flint, T. R., Williams, E. H., Fearon, D. T., Jodrell, D. I., Janowitz, T. (January 2018) Cancer Immunotherapy Trials Underutilize Immune Response Monitoring. Oncologist, 23 (1). pp. 116-117. ISSN 1083-7159

Connell, C. M., Raby, S., Beh, I., Flint, T., Williams, E., Fearon, D. T., Jodrell, D. I., Janowitz, T. (July 2017) Cancer immunotherapy trial registrations increase exponentially but chronic immunosuppressive glucocorticoid therapy may compromise outcomes. Ann Oncol, 28 (7). pp. 1678-1679. ISSN 0923-7534

Flint, Thomas R., Fearon, Douglas T., Janowitz, Tobias (May 2017) Connecting the Metabolic and Immune Responses to Cancer. Trends in Molecular Medicine, 23 (5). pp. 451-464. ISSN 1471-4914

Flint, T. R., Janowitz, T., Connell, C. M., Roberts, E. W., Denton, A. E., Coll, A. P., Jodrell, D. I., Fearon, D. T. (November 2016) Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity. Cell Metab, 24 (5). pp. 672-684. ISSN 1932-7420 (Electronic)1550-4131 (Linking)

Janowitz, T., Thuss-Patience, P., Marshall, A., Kang, J. H., Connell, C., Cook, N., Dunn, J., Park, S. H., Ford, H. (February 2016) Chemotherapy vs supportive care alone for relapsed gastric, gastroesophageal junction, and oesophageal adenocarcinoma: a meta-analysis of patient-level data. Br J Cancer, 114 (4). pp. 381-7. ISSN 0007-0920

Janowitz, T., Welsh, S., Warren, A. Y., Robson, J., Thomas, B., Shaw, A., Ainsworth, N. L., Neal, D. E., Mazhar, D. (October 2015) Prostatic relapse of an undifferentiated teratoma 24 years after orchidectomy. BMC Res Notes, 8. p. 524. ISSN 1756-0500

Lu, L., Yan, H., Shyam-Sundar, V., Janowitz, T. (September 2014) Cross-sectional and longitudinal analysis of cancer vaccination trials registered on the US Clinical Trials Database demonstrates paucity of immunological trial endpoints and decline in registration since 2008. Drug Des Devel Ther, 8. pp. 1539-53. ISSN 1177-8881

Ellul, M., Janowitz, T., Burnet, N. (May 2014) Panhypopituitarism secondary to a solitary hypothalamic metastasis. BMJ Case Rep, 2014. ISSN 1757-790x

Ford, H. E., Marshall, A., Bridgewater, J. A., Janowitz, T., Coxon, F. Y., Wadsley, J., Mansoor, W., Fyfe, D., Madhusudan, S., Middleton, G. W., Swinson, D., Falk, S., Chau, I., Cunningham, D., Kareclas, P., Cook, N., Blazeby, J. M., Dunn, J. A. (January 2014) Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial. Lancet Oncol, 15 (1). pp. 78-86. ISSN 1470-2045

Feig, C., Jones, J. O., Kraman, M., Wells, R. J. B., Deonarine, A., Chan, D. S., Connell, C. M., Roberts, E. W., Zhao, Q., Caballero, O. L., Teichmann, S. A., Janowitz, T., Jodrell, D. I., Tuveson, D. A., Fearon, D. T. (December 2013) Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 110 (50). pp. 20212-20217. ISSN 00278424 (ISSN)

Janowitz, T., Welsh, S. J., Zaki, K., Mulders, P., Eisen, T. (August 2013) Adjuvant therapy in renal cell carcinoma-past, present, and future. Semin Oncol, 40 (4). pp. 482-91. ISSN 0093-7754

Ubhi, B. K., Cheng, K. K., Dong, J., Janowitz, T., Jodrell, D., Tal-Singer, R., MacNee, W., Lomas, D. A., Riley, J. H., Griffin, J. L., Connor, S. C. (October 2012) Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Mol Biosyst, 8 (12). pp. 3125-33. ISSN 1742-2051

Janowitz, T. (January 2011) Biopharmaceuticals and monoclonal antibodies in oncology trials--a cross-sectional analysis. Protein Eng Des Sel, 24 (1-2). pp. 105-11. ISSN 1741-0126

Janowitz, T., Menon, D. K. (April 2010) Exploring new routes for neuroprotective drug development in traumatic brain injury. Sci Transl Med, 2 (27). 27rv1. ISSN 1946-6234

Oliynyk, Z., Briseno-Roa, L., Janowitz, T., Sondergeld, P., Fersht, A. R. (April 2004) Designing a metal-binding site in the scaffold of Escherichia coli KDO8PS. Protein Eng Des Sel, 17 (4). pp. 383-90. ISSN 1741-0126 (Print)1741-0126

Koulen, P., Janowitz, T., Johenning, F. W., Ehrlich, B. E. (October 2001) Characterization of the calcium-release channel/ryanodine receptor from zebrafish skeletal muscle. J Membr Biol, 183 (3). pp. 155-63. ISSN 0022-2631 (Print)0022-2631

Conference or Workshop Item

Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E, Kleeman, Sam O, Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Flint, Thomas R, Connell, Claire M, Lukey, Michael J, White, Eileen P, Coll, Anthony P, Venkitaraman, Ashok R, Janowitz, Tobias (2023) Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023, 2023 Apr 14-19, Orlando, FL.

Lee, Hassal, Bates, Alexander Shakeel, Dima, Richard, Nadella, Sandeep, Jordan-Martin, Nicole, Brennan, Christina, Janowitz, Tobias (2022) Analysis of methods to improve engagement of under-represented and socioeconomically deprived patients in clinical research. In: AACR Special Conference on Pancreatic Cancer.

Janowitz, Tobias, Gablenz, Eva C, Pattinson, David J, Wang, Timothy C, Conigliaro, Joseph, Tracey, Kevin J, Tuveson, David A (September 2020) Famotidine use and quantitative symptom tracking for COVID-19 in nonhospitalized patients: A case series. In: AACR Annual Meeting.

Yan, Ran, Wang, Zhikai, Gao, Ya, Janowitz, Tobias, Fearon, Douglas T (May 2020) Immunogenicity and the CXCL12-coat control T cell accumulation in murine pancreatic cancer. In: UNSPECIFIED. (Unpublished)

Williams, Edward, Whitley, Cameron, Weaver, Jamie, Connell, Claire, Geisler, Reed Stratton, Giglio, Daniel, Tavare, Simon, Jodrell, Duncan, Janowitz, Tobias (November 2018) The CamGFR model for renal function in patients with cancer: Validation and extension for use with data from isotope mass dilution spectrometry creatinine assays. In: National-Cancer-Research-Institute (NCRI) Cancer Conference.

Raby, S, Connell, C, Janowitz, T (April 2016) A comprehensive analysis of immuno- and immunoradiotherapy trial design developments from 2000-2014. In: ESTRO.