Janowitz, Tobias Publications

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Janowitz, Tobias

https://facultyprofiles.cshl.edu/tobias.janowitz
Number of items at this level: 47.

Paper

Kolamunnage-Dona, Ruwanthi, Berhane, Sarah, Potts, Harry, Williams, Edward H, Tanner, James, Janowitz, Tobias, Hoare, Matthew, Johnson, Philip (May 2021) Sorafenib is associated with a reduced rate of tumour growth and liver function deterioration in HCV-induced hepatocellular carcinoma. Journal of Hepatology. ISSN 0168-8278

Yang, Wen-Hsuan, Qiu, Yijian, Stamatatos, Olivia, Janowitz, Tobias, Lukey, Michael J (May 2021) Enhancing the Efficacy of Glutamine Metabolism Inhibitors in Cancer Therapy. Trends in Cancer. ISSN 2405-8033

Janowitz, Tobias, Kleeman, Sam, Vonderheide, Robert H (April 2021) Reconsidering Dexamethasone for Antiemesis when Combining Chemotherapy and Immunotherapy. The Oncologist, 26 (4). pp. 269-273. ISSN 1083-7159

Fearon, Douglas T, Janowitz, Tobias (March 2021) AMD3100/Plerixafor overcomes immune inhibition by the CXCL12-KRT19 coating on pancreatic and colorectal cancer cells. British Journal of Cancer. ISSN 0007-0920

Williams, Edward H, Flint, Thomas R, Connell, Claire M, Giglio, Daniel, Lee, Hassal, Ha, Taehoon, Gablenz, Eva, Bird, Nicholas J, Weaver, James MJ, Potts, Harry, Whitley, Cameron T, Bookman, Michael A, Lynch, Andy G, Meyer, Hannah V, Tavaré, Simon, Janowitz, Tobias (March 2021) CamGFR v2: A New Model for Estimating the Glomerular Filtration Rate from Standardized or Non-standardized Creatinine in Patients with Cancer. Clinical Cancer Research, 27 (5). pp. 1381-1390. ISSN 1078-0432

Munir, Hafsa, Jones, James O, Janowitz, Tobias, Hoffmann, Markus, Euler, Maximilien, Martins, Carla P, Welsh, Sarah J, Shields, Jacqueline D (January 2021) Stromal-driven and Amyloid β-dependent induction of neutrophil extracellular traps modulates tumor growth. Nature Communications, 12 (1). p. 683. ISSN 2041-1723

Biasci, D., Smoragiewicz, M., Connell, C. M., Wang, Z., Gao, Y., Thaventhiran, J. E. D., Basu, B., Magiera, L., Johnson, T. I., Bax, L., Gopinathan, A., Isherwood, C., Gallagher, F. A., Pawula, M., Hudecova, I., Gale, D., Rosenfeld, N., Barmpounakis, P., Popa, E. C., Brais, R., Godfrey, E., Mir, F., Richards, F. M., Fearon, D. T., Janowitz, T., Jodrell, D. I. (November 2020) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. Proc Natl Acad Sci U S A, 117 (46). pp. 28960-28970. ISSN 0027-8424 (Print)0027-8424

Weber, A. G., Chau, A. S., Egeblad, M., Barnes, B. J., Janowitz, T. (September 2020) Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: a case series. Mol Med, 26 (1). p. 91. ISSN 1076-1551 (Print)1076-1551

Wang, Zhikai, Yan, Ran, Li, Jiayun, Gao, Ya, Moresco, Philip, Yao, Min, Hechtman, Jaclyn F, Weiss, Matthew J, Janowitz, Tobias, Fearon, Douglas T (September 2020) Pancreatic cancer cells assemble a CXCL12-keratin 19 coating to resist immunotherapy. BioRxiv. (Unpublished)

Biasci, D., Smoragiewicz, M., Connell, C. M., Wang, Z., Gao, Y., Thaventhiran, J. E., Basu, B., Magiera, L., Johnson, I. T., Bax, L., Gopinathan, A., Isherwood, C., Gallagher, F., Pawula, M., Hudecova, I., Gale, D., Rosenfeld, N., Barmpounakis, P., Popa, E. C., Brais, R., Godfrey, E., Mir, F., Richards, F., Fearon, D. T., Janowitz, T., Jodrell, D. (July 2020) CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response. medRxiv. (Unpublished)

Janowitz, T., Gablenz, E., Pattinson, D., Wang, T.C., Conigliaro, J., Tracey, K., Tuveson, D. (June 2020) Famotidine Use and Quantitative Symptom Tracking for COVID-19 in Non-Hospitalised Patients: A Case Series. Gut, 69 (9). pp. 1592-1597. ISSN 1468-3288

Weber, Andrew G, Chau, Alice S, Egeblad, Mikala, Barnes, Betsy J, Janowitz, Tobias (May 2020) Nebulized in-line endotracheal dornase alfa and albuterol administered to mechanically ventilated COVID-19 patients: A case series. MedRxiv. (Unpublished)

Janowitz, T., Tuveson, D. A. (May 2020) The Era of COVID-19 and the Rise of Science Collectivism in Cancer Research. Cancer Discov, 10 (7). pp. 913-915. ISSN 2159-8274

Sahai, E., Astsaturov, I., Cukierman, E., DeNardo, D. G., Egeblad, M., Evans, R. M., Fearon, D., Greten, F. R., Hingorani, S. R., Hunter, T., Hynes, R. O., Jain, R. K., Janowitz, T., Jorgensen, C., Kimmelman, A. C., Kolonin, M. G., Maki, R. G., Powers, R. S., Pure, E., Ramirez, D. C., Scherz-Shouval, R., Sherman, M. H., Stewart, S., Tlsty, T. D., Tuveson, D. A., Watt, F. M., Weaver, V., Weeraratna, A. T., Werb, Z. (March 2020) A framework for advancing our understanding of cancer-associated fibroblasts. Nat Rev Cancer, 20 (3). pp. 174-186. ISSN 1474-175x

Connell, Claire M, Brais, Rebecca, Whitaker, Hayley, Upponi, Sara, Beh, Ian, Risdall, Jane, Corrie, Pippa, Janowitz, Tobias, Jodrell, Duncan I (January 2020) Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report. BMC Cancer, 20 (1). p. 38. ISSN 1471-2407

Munir, Hafsa, Jones, James O, Janowitz, Tobias, Martins, Carla P, Welsh, Sarah J, Shields, Jacqueline D (January 2020) Stromal Amyloid β drives Neutrophil extracellular trap formation to augment tumour growth. BioRxiv. (Unpublished)

Williams, Edward H, Connell, Claire M, Weaver, James MJ, Beh, Ian, Potts, Harry, Whitley, Cameron T, Bird, Nicholas, Al-Sayed, Tamer, Monaghan, Phillip J, Fehr, Martin, Cathomas, Richard, Bertelli, Gianfilippo, Quinton, Amy, Lewis, Paul, Shamash, Jonathan, Wilson, Peter, Dooley, Michael, Poole, Susan, Mark, Patrick B, Bookman, Michael A, Earl, Helena, Jodrell, Duncan, Tavaré, Simon, Lynch, Andy G, Janowitz, Tobias (December 2019) Multicenter Validation of the CamGFR Model for Estimated Glomerular Filtration Rate. JNCI Cancer Spectrum, 3 (4). pkz068. ISSN 2515-5091

Luo, Y., Yang, Y., Liu, M., Wang, D., Wang, F., Bi, Y., Ji, J., Li, S., Liu, Y., Chen, R., Huang, H., Wang, X., Swidnicka-Siergiejko, A. K., Janowitz, T., Beyaz, S., Wang, G., Xu, S., Bialkowska, A. B., Luo, C. K., Pin, C. L., Liang, G., Lu, X., Wu, M., Shroyer, K. R., Wolff, R. A., Plunkett, W., Ji, B., Li, Z., Li, E., Li, X., Yang, V. W., Logsdon, C. D., Abbruzzese, J. L., Lu, W. (July 2019) Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet. Gastroenterology, 157 (5). ISSN 0016-5085

Janowitz, T. (July 2018) Cancer: The Tumor-Driven Disease of the Host. Cell Metab, 28 (1). pp. 5-6. ISSN 1550-4131

Sng, C. C. T., O'Byrne, S., Prigozhin, D. M., Bauer, M. R., Harvey, J. C., Ruhle, M., Challis, B. G., Lear, S., Roberts, L. D., Workman, S., Janowitz, T., Magiera, L., Doffinger, R., Buckland, M. S., Jodrell, D. J., Semple, R. K., Wilson, T. J., Modis, Y., Thaventhiran, J. E. D. (July 2018) A type III complement factor D deficiency: Structural insights for inhibition of the alternative pathway. J Allergy Clin Immunol, 142 (1). 311-314.e6. ISSN 0091-6749

Casey, R. T., Giger, O., Seetho, I., Marker, A., Pitfield, D., Boyle, L. H., Gurnell, M., Shaw, A., Tischowitz, M., Maher, E. R., Chatterjee, V. K., Janowitz, T., Mells, G., Corrie, P., Challis, B. G. (June 2018) Rapid disease progression in a patient with mismatch repair-deficient and cortisol secreting adrenocortical carcinoma treated with pembrolizumab. Semin Oncol. ISSN 0093-7754

Flint, T. R., Jones, J. O., Ferrer, M., Colucci, F., Janowitz, T. (March 2018) A comparative analysis of immune privilege in pregnancy and cancer in the context of checkpoint blockade immunotherapy. Semin Oncol. ISSN 0093-7754

Connell, C. M., Raby, S. E. M., Beh, I., Flint, T. R., Williams, E. H., Fearon, D. T., Jodrell, D. I., Janowitz, T. (January 2018) Cancer Immunotherapy Trials Underutilize Immune Response Monitoring. Oncologist, 23 (1). pp. 116-117. ISSN 1083-7159

Janowitz, T., Williams, E. H., Marshall, A., Ainsworth, N., Thomas, P. B., Sammut, S. J., Shepherd, S., White, J., Mark, P. B., Lynch, A. G., Jodrell, D. I., Tavare, S., Earl, H. (August 2017) New Model for Estimating Glomerular Filtration Rate in Patients With Cancer. J Clin Oncol, 35 (24). pp. 2798-2805. ISSN 0732-183x

Connell, C. M., Raby, S., Beh, I., Flint, T., Williams, E., Fearon, D. T., Jodrell, D. I., Janowitz, T. (July 2017) Cancer immunotherapy trial registrations increase exponentially but chronic immunosuppressive glucocorticoid therapy may compromise outcomes. Ann Oncol, 28 (7). pp. 1678-1679. ISSN 0923-7534

Flint, Thomas R., Fearon, Douglas T., Janowitz, Tobias (May 2017) Connecting the Metabolic and Immune Responses to Cancer. Trends in Molecular Medicine, 23 (5). pp. 451-464. ISSN 1471-4914

Fessas, P., Lee, H., Ikemizu, S., Janowitz, T. (April 2017) A molecular and preclinical comparison of the PD-1-targeted T-cell checkpoint inhibitors nivolumab and pembrolizumab. Semin Oncol, 44 (2). pp. 136-140. ISSN 0093-7754

Flint, T. R., Janowitz, T., Connell, C. M., Roberts, E. W., Denton, A. E., Coll, A. P., Jodrell, D. I., Fearon, D. T. (November 2016) Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity. Cell Metab, 24 (5). pp. 672-684. ISSN 1932-7420 (Electronic)1550-4131 (Linking)

Janowitz, T., Thuss-Patience, P., Marshall, A., Kang, J. H., Connell, C., Cook, N., Dunn, J., Park, S. H., Ford, H. (February 2016) Chemotherapy vs supportive care alone for relapsed gastric, gastroesophageal junction, and oesophageal adenocarcinoma: a meta-analysis of patient-level data. Br J Cancer, 114 (4). pp. 381-7. ISSN 0007-0920

Janowitz, T., Welsh, S., Warren, A. Y., Robson, J., Thomas, B., Shaw, A., Ainsworth, N. L., Neal, D. E., Mazhar, D. (October 2015) Prostatic relapse of an undifferentiated teratoma 24 years after orchidectomy. BMC Res Notes, 8. p. 524. ISSN 1756-0500

Gill, A. B., Anandappa, G., Patterson, A. J., Priest, A. N., Graves, M. J., Janowitz, T., Jodrell, D. I., Eisen, T., Lomas, D. J. (February 2015) The use of error-category mapping in pharmacokinetic model analysis of dynamic contrast-enhanced MRI data. Magn Reson Imaging, 33 (2). pp. 246-51. ISSN 0730-725x

Lu, L., Yan, H., Shyam-Sundar, V., Janowitz, T. (September 2014) Cross-sectional and longitudinal analysis of cancer vaccination trials registered on the US Clinical Trials Database demonstrates paucity of immunological trial endpoints and decline in registration since 2008. Drug Des Devel Ther, 8. pp. 1539-53. ISSN 1177-8881

Ellul, M., Janowitz, T., Burnet, N. (May 2014) Panhypopituitarism secondary to a solitary hypothalamic metastasis. BMJ Case Rep, 2014. ISSN 1757-790x

Li, L. M., Menon, D. K., Janowitz, T. (January 2014) Cross-sectional analysis of data from the U.S. clinical trials database reveals poor translational clinical trial effort for traumatic brain injury, compared with stroke. PLoS One, 9 (1). e84336. ISSN 1932-6203

Ford, H. E., Marshall, A., Bridgewater, J. A., Janowitz, T., Coxon, F. Y., Wadsley, J., Mansoor, W., Fyfe, D., Madhusudan, S., Middleton, G. W., Swinson, D., Falk, S., Chau, I., Cunningham, D., Kareclas, P., Cook, N., Blazeby, J. M., Dunn, J. A. (January 2014) Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial. Lancet Oncol, 15 (1). pp. 78-86. ISSN 1470-2045

Feig, C., Jones, J. O., Kraman, M., Wells, R. J. B., Deonarine, A., Chan, D. S., Connell, C. M., Roberts, E. W., Zhao, Q., Caballero, O. L., Teichmann, S. A., Janowitz, T., Jodrell, D. I., Tuveson, D. A., Fearon, D. T. (December 2013) Targeting CXCL12 from FAP-expressing carcinoma-associated fibroblasts synergizes with anti-PD-L1 immunotherapy in pancreatic cancer. Proceedings of the National Academy of Sciences of the United States of America, 110 (50). pp. 20212-20217. ISSN 00278424 (ISSN)

Janowitz, T., Welsh, S. J., Zaki, K., Mulders, P., Eisen, T. (August 2013) Adjuvant therapy in renal cell carcinoma-past, present, and future. Semin Oncol, 40 (4). pp. 482-91. ISSN 0093-7754

Ubhi, B. K., Cheng, K. K., Dong, J., Janowitz, T., Jodrell, D., Tal-Singer, R., MacNee, W., Lomas, D. A., Riley, J. H., Griffin, J. L., Connor, S. C. (October 2012) Targeted metabolomics identifies perturbations in amino acid metabolism that sub-classify patients with COPD. Mol Biosyst, 8 (12). pp. 3125-33. ISSN 1742-2051

Janowitz, T. (January 2011) Biopharmaceuticals and monoclonal antibodies in oncology trials--a cross-sectional analysis. Protein Eng Des Sel, 24 (1-2). pp. 105-11. ISSN 1741-0126

Janowitz, T., Menon, D. K. (April 2010) Exploring new routes for neuroprotective drug development in traumatic brain injury. Sci Transl Med, 2 (27). 27rv1. ISSN 1946-6234

Oliynyk, Z., Briseno-Roa, L., Janowitz, T., Sondergeld, P., Fersht, A. R. (April 2004) Designing a metal-binding site in the scaffold of Escherichia coli KDO8PS. Protein Eng Des Sel, 17 (4). pp. 383-90. ISSN 1741-0126 (Print)1741-0126

Koulen, P., Janowitz, T., Johenning, F. W., Ehrlich, B. E. (October 2001) Characterization of the calcium-release channel/ryanodine receptor from zebrafish skeletal muscle. J Membr Biol, 183 (3). pp. 155-63. ISSN 0022-2631 (Print)0022-2631

Koulen, P., Janowitz, T., Johnston, L. D., Ehrlich, B. E. (September 2000) Conservation of localization patterns of IP(3) receptor type 1 in cerebellar Purkinje cells across vertebrate species. J Neurosci Res, 61 (5). pp. 493-9. ISSN 0360-4012 (Print)0360-4012

Conference or Workshop Item

Janowitz, Tobias, Gablenz, Eva C, Pattinson, David J, Wang, Timothy C, Conigliaro, Joseph, Tracey, Kevin J, Tuveson, David A (September 2020) Famotidine use and quantitative symptom tracking for COVID-19 in nonhospitalized patients: A case series. In: AACR Annual Meeting.

Yan, Ran, Wang, Zhikai, Gao, Ya, Janowitz, Tobias, Fearon, Douglas T (May 2020) Immunogenicity and the CXCL12-coat control T cell accumulation in murine pancreatic cancer. In: UNSPECIFIED. (Unpublished)

Williams, Edward, Whitley, Cameron, Weaver, Jamie, Connell, Claire, Geisler, Reed Stratton, Giglio, Daniel, Tavare, Simon, Jodrell, Duncan, Janowitz, Tobias (November 2018) The CamGFR model for renal function in patients with cancer: Validation and extension for use with data from isotope mass dilution spectrometry creatinine assays. In: National-Cancer-Research-Institute (NCRI) Cancer Conference.

Raby, S, Connell, C, Janowitz, T (April 2016) A comprehensive analysis of immuno- and immunoradiotherapy trial design developments from 2000-2014. In: ESTRO.

This list was generated on Sun Sep 19 22:59:54 2021 EDT.
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