Items where Subject is "apoptosis"

A

Aguirre-Chen, C., Hammell, C. M. (2014) Cell death machinery makes life more robust. Elife, 3. e05816. ISSN 2050-084X (Electronic)2050-084X (Linking)

Anczukow, O., Rosenberg, A. Z., Akerman, M., Das, S., Zhan, L., Karni, R., Muthuswamy, S. K., Krainer, A. R. (January 2012) The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation. Nature Structural Molecular Biology, 19 (2). pp. 220-228. ISSN 1545-9985 (Electronic)1545-9985 (Linking)

Aranda, V., Haire, T., Nolan, M. E., Calarco, J. P., Rosenberg, A. Z., Fawcett, J. P., Pawson, T., Muthuswamy, S. K. (November 2006) Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nat Cell Biol, 8 (11). pp. 1235-45. ISSN 1465-7392 (Print)

Arrazola, M. S., Saquel, C., Catalan, R. J., Barrientos, S. A., Hernandez, D. E., Catenaccio, A., Court, F. A. (May 2019) Axonal degeneration is mediated by necroptosis activation Necroptosis mediates axonal degeneration. J Neurosci, 39 (20). pp. 3832-2844. ISSN 0270-6474

Attardi, L. D., Reczek, E. E., Cosmas, C., Demicco, E. G., McCurrach, M. E., Lowe, S. W., Jacks, T. (March 2000) PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. Genes & Development, 14 (6). pp. 704-718. ISSN 0890-9369

B

Barth, N. D., Subiros-Funosas, R., Mendive-Tapia, L., Duffin, R., Shields, M. A., Cartwright, J. A., Henriques, S. T., Sot, J., Goñi, F. M., Lavilla, R., Marwick, J. A., Vermeren, S., Rossi, A. G., Egeblad, M., Dransfield, I., Vendrell, M. (August 2020) A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis. Nat Commun, 11 (1). p. 4027. ISSN 2041-1723

Barth, Nicole, Mendive-Tapia, Lorena, Subiros-Funosas, Ramon, Ghashghaie, Ouldouz, Lavilla, Rodolfo, Maiorino, Laura, He, Xue-Yan, Dransfield, Ian, Egeblad, Mikala, Vendrell, Marc (November 2021) A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-induced Cancer Cell Death. Angewandte Chemie International Edition. ISSN 1433-7851

Bellows, D. S., Chau, B. N., Lee, P., Lazebnik, Y., Burns, W. H., Hardwick, J. M. (2000) Antiapoptotic herpesvirus Bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteins. Journal of Virology, 74 (11). pp. 5024-5031. ISSN 0022-538X

Belov, George A., Romanova, Lyudmila I., Tolskaya, Elena A., Kolesnikova, Marina S., Lazebnik, Yuri A., Agol, Vadim I. (2003) The major apoptotic pathway activated and suppressed by poliovirus. Journal of Virology, 77 (1). pp. 45-56. ISSN 0022-538X

Bencze, G., Bencze, S., Rivera, K. D., Watson, J. D., Orfi, L., Tonks, N. K., Pappin, D. J. (August 2020) Mito-oncology agent: fermented extract suppresses the Warburg effect, restores oxidative mitochondrial activity, and inhibits in vivo tumor growth. Sci Rep, 10 (1). p. 14174. ISSN 2045-2322

Biffi, G., Oni, T. E., Spielman, B., Hao, Y., Elyada, E., Park, Y., Preall, J., Tuveson, D. A. (October 2018) IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma. Cancer Discov, 9 (2). pp. 282-301. ISSN 2159-8274

Bivona, T. G., Hieronymus, H., Parker, J., Chang, K., Taron, M., Rosell, R., Moonsamy, P., Dahlman, K., Miller, V. A., Costa, C., Hannon, G. J., Sawyers, C. L. (March 2011) FAS and NF-kappa B signalling modulate dependence of lung cancers on mutant EGFR. Nature, 471 (7339). pp. 523-526. ISSN 0028-0836

Bodineau, Clément, Tomé, Mercedes, Courtois, Sarah, Costa, Ana SH, Sciacovelli, Marco, Rousseau, Benoit, Richard, Elodie, Vacher, Pierre, Parejo-Pérez, Carlos, Bessede, Emilie, Varon, Christine, Soubeyran, Pierre, Frezza, Christian, Murdoch, Piedad Del Socorro, Villar, Victor H, Durán, Raúl V (August 2021) Two parallel pathways connect glutamine metabolism and mTORC1 activity to regulate glutamoptosis. Nature Communications, 12 (1). p. 4814. ISSN 2041-1723

Brancolini, Claudio, Lazarevic, Dean, Rodriguez, Joe, Schneider, Claudio (November 1997) Dismantling Cell-Cell Contacts during Apoptosis Is Coupled to a Caspase-dependent Proteolytic Cleavage of beta -Catenin. Journal of Cell Biology, 139 (3). pp. 759-771. ISSN 0021-9525

C

Carroll, D. K., Carroll, J. S., Leong, C. O., Cheng, F., Brown, M., Mills, A. A., Brugge, J. S., Ellisen, L. W. (June 2006) p63 regulates an adhesion programme and cell survival in epithelial cells. Nature Cell Biology, 8 (6). pp. 551-561. ISSN 14657392

Catizone, Allison N, Good, Charly Ryan, Alexander, Katherine A, Berger, Shelley L, Sammons, Morgan A (April 2019) Comparison of genotoxic versus nongenotoxic stabilization of p53 provides insight into parallel stress-responsive transcriptional networks. Cell Cycle, 18 (8). pp. 809-823. ISSN 1538-4101

Chen, Hsu-Hsin, Welling, Maaike, Bloch, Donald B, Muñoz, Javier, Mientjes, Edwin, Chen, Xinjie, Tramp, Cody, Wu, Jie, Yabuuchi, Akiko, Chou, Yu-Fen, Buecker, Christa, Krainer, Adrian, Willemsen, Rob, Heck, Albert J, Geijsen, Niels (October 2014) DAZL Limits Pluripotency, Differentiation, and Apoptosis in Developing Primordial Germ Cells. Stem Cell Reports, 3 (5). pp. 892-904. ISSN 2213-6711

Cheng, J., Zhu, Y., He, S., Lu, Y., Chen, J., Han, B., Petrillo, M., Wrzeszczynski, K. O., Yang, S., Dai, P., Zhai, S., Han, D., Zhang, M. Q., Li, W., Liu, X., Li, H., Chen, Z. Y., Yuan, H. (July 2011) Functional Mutation of SMAC/DIABLO, Encoding a Mitochondrial Proapoptotic Protein, Causes Human Progressive Hearing Loss DFNA64. The American Journal of Human Genetics, 89 (1). pp. 56-66. ISSN 0002-9297

Cheung, E. C., DeNicola, G. M., Nixon, C., Blyth, K., Labuschagne, C. F., Tuveson, D. A., Vousden, K. H. (January 2020) Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer. Cancer Cell. ISSN 1535-6108

Chung, S. B., Gumienny, T. L., Hengartner, M. O., Driscoll, M. (December 2000) A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C-elegans. Nature Cell Biology, 2 (12). pp. 931-937. ISSN 1465-7392

Cifra, A., Lowe, S.W (November 2015) Exploring cell apoptosis and senescence to understand and treat cancer: an interview with Scott Lowe. Dis Model Mech, 8 (11). pp. 1345-8. ISSN 1754-8411 (Electronic)1754-8403 (Linking)

Connell, L. E., Helfman, D. M. (June 2006) Myosin light chain kinase plays a role in the regulation of epithelial cell survival. J Cell Sci, 119 (Pt 11). pp. 2269-81. ISSN 0021-9533 (Print)

Connell, L. E., Helfman, D. M. (November 2001) Role of actin and myosin in apoptosis in normal and Ras-transformed MDCK cells. Molecular Biology of the Cell, 12. 194A-195A. ISSN 1059-1524

Cormier, C. (2006) Alternative Apoptotic Pathways in Cancer Cells. PhD thesis, Cold Spring Harbor Laboratory.

D

Davey, S., Beach, D. (October 1995) RACH2, a novel human gene that complements a fission yeast cell cycle checkpoint mutation. Mol Biol Cell, 6 (10). pp. 1411-21. ISSN 1059-1524 (Print)

Desnoyers, S., Hengartner, M. O. (1997) Genetics of apoptosis. Advances in Pharmacology, 41. pp. 35-56. ISSN 1054-3589 (Print)

Dorstyn, L., Mills, K., Lazebnik, Y., Kumar, S. (November 2004) The two cytochrome c species, DC3 and DC4, are not required for caspase activation and apoptosis in Drosophila cells. Journal of Cell Biology, 167 (3). pp. 405-410. ISSN 0021-9525

Duelli, D. M., Lazebnik, Y. A. (2000) Primary cells suppress oncogene-dependent apoptosis. Nature Cell Biology, 2 (11). pp. 859-862. ISSN 1465-7392

da Fonseca, R. R., Kosiol, C., Vinar, T., Siepel, A., Nielsen, R. (February 2010) Positive selection on apoptosis related genes. FEBS Lett, 584 (3). pp. 469-76. ISSN 0014-5793

de Stanchina, E., Querido, E., Narita, M., Davuluri, R. V., Pandolfi, P. P., Ferbeyre, G., Lowe, S. W. (February 2004) PML is a direct p53 target that modulates p53 effector functions. Mol Cell, 13 (4). pp. 523-35. ISSN 1097-2765 (Print)

E

Eifert, C., Wang, X., Kokabee, L., Kourtidis, A., Jain, R., Gerdes, M. J., Conklin, D. S. (October 2013) A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis. Genes Chromosomes and Cancer, 52 (10). pp. 961-975. ISSN 10452257

Ellis, L., Bots, M., Lindemann, R. K., Bolden, J. E., Newbold, A., Cluse, L. A., Scott, C. L., Strasser, A., Atadja, P., Lowe, S. W., Johnstone, R. W. (July 2009) The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy. Blood, 114 (2). pp. 380-393.

Ellis, L., Lindemann, R., Newbold, A., Whitecross, K., Cluse, L., Pelligrini, M., Wei, A., Scott, C., Atadja, P., Lowe, S. W., Johnstone, R. W. (December 2007) Characterization of the apoptotic and therapeutic activities of the histone deacetylase inhibitors LAQ824 and LBH589 using a mouse model of B cell lymphoma. Molecular Cancer Therapeutics, 6 (11). 3475S-3476S. ISSN 1535-7163

F

Faleiro, L., Kobayashi, R., Fearnhead, H., Lazebnik, Y. (1997) Multiple species of CPP32 and Mch2 are the major active caspases present in apoptotic cells. Embo Journal, 16 (9). pp. 2271-2281. ISSN 0261-4189

Faleiro, L., Lazebnik, Y. (2000) Caspases disrupt the nuclear-cytoplasmic barrier. J Cell Biol, 151 (5). pp. 951-959. ISSN 0021-9525

Fearnhead, H. O., McCurrach, M. E., O'Neill, J., Zhang, K., Lowe, S. W., Lazebnik, Y. A. (1997) Oncogene-dependent apoptosis in extracts from drug-resistant cells. Genes Dev, 11 (10). pp. 1266-1276. ISSN 0890-9369

Fearnhead, H. O., Rodriguez, J., Govek, E. E., Guo, W., Kobayashi, R., Hannon, G., Lazebnik, Y. A. (1998) Oncogene-dependent apoptosis is mediated by caspase-9. Proc Natl Acad Sci U S A, 95 (23). pp. 13664-13669. ISSN 0027-8424

Fein, Miriam R, He, Xue-Yan, Almeida, Ana S, Bružas, Emilis, Pommier, Arnaud, Yan, Ran, Eberhardt, Anaïs, Fearon, Douglas T, Van Aelst, Linda, Wilkinson, John Erby, Dos Santos, Camila O, Egeblad, Mikala (October 2020) Cancer cell CCR2 orchestrates suppression of the adaptive immune response. Journal of Experimental Medicine, 217 (10). ISSN 0022-1007

Finnberg, N., Gruber, J. J., Fei, P. W., Rudolph, D., Bric, A., Kim, S. H., Burns, T. F., Ajuha, H., Page, R., Wu, G. S., Chen, Y. H., McKenna, W. G., Bernhard, E., Lowe, S., Mak, T., El-Deiry, W. S. (March 2005) DR5 knockout mice are compromised in radiation-induced apoptosis. Molecular and Cellular Biology, 25 (5). pp. 2000-2013. ISSN 0270-7306

Fisher, Matthew L, Balinth, Seamus, Hwangbo, Yon, Wu, Caizhi, Ballon, Carlos, Wilkinson, John E, Goldberg, Gary L, Mills, Alea A (October 2021) BRD4 REGULATES TRANSCRIPTION FACTOR ∆Np63αTO DRIVE A CANCER STEM CELL PHENOTYPE IN SQUAMOUS CELL CARCINOMAS. Cancer Research. canres.0707.2021-canres.0707.2021. ISSN 0008-5472

Flinterman, M. B., Mymryk, J. S., Klanrit, P., Yousef, A. F., Lowe, S. W., Caldas, C., Gaken, J., Farzaneh, F., Tavassoli, M. (November 2007) p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing. Oncogene, 26 (48). pp. 6863-6874. ISSN 0950-9232

Franchin, Cinzia, Cesaro, Luca, Salvi, Mauro, Millioni, Renato, Iori, Elisabetta, Cifani, Paolo, James, Peter, Arrigoni, Giorgio, Pinna, Lorenzo (June 2015) Quantitative analysis of a phosphoproteome readily altered by the protein kinase CK2 inhibitor quinalizarin in HEK-293T cells. BBA: Proteins and Proteomics, 1854 (6). pp. 609-623. ISSN 1570-9639

Fraser, A., James, C. (June 1998) Fermenting debate: do yeast undergo apoptosis? Trends In Cell Biology, 8 (6). pp. 219-21. ISSN 0962-8924

Fridman, J. S., Lowe, S. W. (December 2003) Control of apoptosis by p53. Oncogene, 22 (56). pp. 9030-9040. ISSN 0950-9232

Froeling, F. E. M., Mosur Swamynathan, M., Deschenes, A., Chio, I. I. C., Brosnan, E., Yao, M. A., Alagesan, P., Lucito, M. S., Li, J., Chang, A. Y., Trotman, L. C., Belleau, P., Park, Y., Rogoff, H. A., Watson, J. D., Tuveson, D. A. (September 2019) Bioactivation of napabucasin triggers reactive oxygen species-mediated cancer cell death. Clin Cancer Res, 25 (23). pp. 7162-7174. ISSN 1078-0432 (Print)1078-0432

G

Galaktionov, K., Chen, X., Beach, D. (August 1996) Cdc25 cell-cycle phosphatase as a target of c-myc. Nature, 382 (6591). pp. 511-7. ISSN 0028-0836 (Print)

Gartner, A., Milstein, S., Ahmed, S., Hodgkin, J., Hengartner, M. O. (March 2000) A conserved checkpoint pathway mediates DNA damage-induced apoptosis and cell cycle arrest in C. elegans. Molecular Cell, 5 (3). pp. 435-443. ISSN 1097-2765

Glaser, S. P., Lee, E. F., Trounson, E., Bouillet, P., Wei, A., Fairlie, W. D., Izon, D. J., Zuber, J., Rappaport, A. R., Herold, M. J., Alexander, W. S., Lowe, S. W., Robb, L., Strasser, A. (January 2012) Anti-apoptotic mcl-1 is essential for the development and sustained growth of acute myeloid leukemia. Genes and Development, 26 (2). pp. 120-125. ISSN 08909369 (ISSN)

Gu, L., Zheng, H. W., Murray, S. A., Ying, H. Q., Xiao, Z. X. J. (March 2003) Deregulation of Cdc2 kinase induces caspase-3 activation and apoptosis. Biochemical and Biophysical Research Communications, 302 (2). pp. 384-391. ISSN 0006-291X

Gumienny, T. L., Hengartner, M. O. (June 2001) How the worm removes corpses: the nematode C-elegans as a model system to study engulfment. Cell Death and Differentiation, 8 (6). pp. 564-568. ISSN 1350-9047

Gumienny, T. L., Lambie, E., Hartwieg, E., Horvitz, H. R., Hengartner, M. O. (February 1999) Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline. Development, 126 (5). pp. 1011-22. ISSN 0950-1991 (Print)

Guo, T., Hajdu, M., Agaram, N. P., Shinoda, H., Veach, D., Clarkson, B. D., Maki, R. G., Singer, S., Dematteo, R. P., Besmer, P., Antonescu, C. R. (November 2009) Mechanisms of sunitinib resistance in gastrointestinal stromal tumors harboring KITAY502-3ins mutation: an in vitro mutagenesis screen for drug resistance. Clin Cancer Res, 15 (22). pp. 6862-70. ISSN 1078-0432 (Print)1078-0432 (Linking)

Guo, X. C., Mills, A. A. (February 2007) p63, cellular senescence and tumor development. Cell Cycle, 6 (3). pp. 305-11. ISSN 1538-4101

H

Hegde, Ramesh, Srinivasula, Srinivasa M., Zhang, ZhiJia, Wassell, Richard, Mukattash, Rula, Cilenti, Lucia, DuBois, Garrett, Lazebnik, Yuri, Zervos, Antonis S., Fernandes-Alnemri, Teresa, Alnemri, Emad S. (2002) Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction. Journal of Biological Chemistry, 277 (1). pp. 432-438. ISSN 0021-9258

Hemann, M. T., Bric, A., Teruya-Feldstein, J., Herbst, A., Nilsson, J. A., Cordon-Cardo, C., Cleveland, J. L., Tansey, W. P., Lowe, S. W. (August 2005) Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants. Nature, 436 (7052). pp. 807-11. ISSN 1476-4687 (Electronic)

Hemann, M. T., Lowe, S. W. (August 2006) The p53-Bcl-2 connection. Cell Death Differ, 13 (8). pp. 1256-9. ISSN 1350-9047 (Print)

Hemish, J., Nakaya, N., Mittal, V., Enikolopov, G. (October 2003) Nitric oxide activates diverse signaling pathways to regulate gene expression. Journal of Biological Chemistry, 278 (43). pp. 42321-42329. ISSN 0021-9258

Hengartner, M. (August 1998) Apoptosis. Death by crowd control. Science, 281 (5381). pp. 1298-9. ISSN 0036-8075 (Print)

Hengartner, M. O. (1997) Apoptosis and the shape of death. Developmental Genetics, 21 (4). pp. 245-8. ISSN 0192-253X (Print)

Hengartner, M. O. (February 2001) Apoptosis: Corralling the corpses. Cell, 104 (3). pp. 325-328. ISSN 0092-8674

Hengartner, M. O. (July 1997) Genetic control of programmed cell death and aging in the nematode Caenorhabditis elegans. Experimental Gerontology, 32 (4-5). pp. 363-74. ISSN 0531-5565 (Print)

Hengartner, M. O. (June 1995) Out-of body experiences: cell-free cell death. Bioessays, 17 (6). pp. 549-52. ISSN 0265-9247 (Print)

Hengartner, M. O. (November 1995) Pharmacia Biotech & Science prize. Grand prize winner. Life and death decisions: ced-9 and programmed cell death in Caenorhabditis elegans. Science, 270 (5238). pp. 930-1. ISSN 0036-8075 (Print)

Hengartner, M. O. (February 1996) Programmed cell death in invertebrates. Curr Opin Genet Dev, 6 (1). pp. 34-8. ISSN 0959-437X (Print)

Hengartner, M. O. (1999) Programmed cell death in the nematode C. elegans. Recent Progress in Hormone Research, 54. 213-22; discussion 222. ISSN 0079-9963 (Print)

Hengartner, M. O. (October 2000) The biochemistry of apoptosis. Nature, 407 (6805). pp. 770-776. ISSN 0028-0836

Hengartner, M. O., Bryant, J. A. (2000) Apoptotic cell death: from worms to wombats ... but what about the weeds? In: Symp Soc Exp Biol. Symposia of the Society for Experimental Biology, 52 . The Company of Biologists Limited, Cambridge, pp. 1-12. ISBN 0081-1386 (Print)

Hengartner, M. O., Horvitz, H. R. (August 1994) Programmed cell death in Caenorhabditis elegans. Curr Opin Genet Dev, 4 (4). pp. 581-6. ISSN 0959-437X (Print)

Hengartner, Michael O. (October 1994) Programmed cell death. A rich harvest. Curr Biol, 4 (10). pp. 950-2. ISSN 0960-9822 (Print)

Herbst, A., Hemann, M. T., Tworkowski, K. A., Salghetti, S. E., Lowe, S. W., Tansey, W. P. (February 2005) A conserved element in Myc that negatively regulates its proapoptotic activity. EMBO Rep, 6 (2). pp. 177-83. ISSN 1469-221X (Print)

Hirao, A., Cheung, A., Duncan, G., Girard, P. M., Elia, A. J., Wakeham, A., Okada, H., Sarkissian, T., Wong, J. A., Sakai, T., de Stanchina, E., Bristow, R. G., Suda, T., Lowe, S. W., Jeggo, P. A., Elledge, S. J., Mak, T. W. (September 2002) Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Molecular and Cellular Biology, 22 (18). pp. 6521-6532. ISSN 0270-7306

Hoeppner, D. J., Hengartner, M. O., Fisher, D. E. (March 1996) Programmed cell death: from development to disease. Meeting report. Biochimica et Biophysica Acta - Reviews on Cancer, 1242 (3). pp. 217-20. ISSN 0006-3002 (Print)

Hoeppner, D. J., Hengartner, M. O., Schnabel, R. (July 2001) Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans. Nature, 412 (6843). pp. 202-206. ISSN 0028-0836

Hoeppner, D. J., Spector, M. S., Ratliff, T. M., Kinchen, J. M., Granat, S., Lin, S. C., Bhusri, S. S., Conradt, B., Herman, M. A., Hengartner, M. O. (October 2004) eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans. Dev Biol, 274 (1). pp. 125-38. ISSN 0012-1606 (Print)

Hofmann, E. R., Milstein, S., Boulton, S. J., Ye, M. J., Hofmann, J. J., Stergiou, L., Gartner, A., Vidal, M., Hengartner, M. O. (November 2002) Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis. Current Biology, 12 (22). pp. 1908-1918. ISSN 0960-9822

Houwing, S., Kamminga, L. M., Berezikov, E., Cronembold, D., Girard, A., van den Elst, H., Filippov, D. V., Blaser, H., Raz, E., Moens, C. B., Plasterk, R. H. A., Hannon, G. J., Draper, B. W., Ketting, R. F. (April 2007) A role for Piwi and piRNAs in germ cell maintenance and transposon silencing in zebrafish. Cell, 129 (1). pp. 69-82. ISSN 0092-8674

J

Jaattela, M., Wissing, D., Kokholm, K., Kallunki, T., Egeblad, M. (November 1998) Hsp70 exerts its anti-apoptotic function downstream of caspase-3-like proteases. EMBO Journal, 17 (21). pp. 6124-34. ISSN 0261-4189 (Print)0261-4189

Jacobs, W. B., Govoni, G., Ho, D., Atwal, J. K., Barnabe-Heider, F., Keyes, W. M., Mills, A. A., Miller, F. D., Kaplan, D. R. (December 2005) p63 is an essential proapoptotic protein during neural development. Neuron, 48 (5). pp. 743-756. ISSN 0896-6273

Johnstone, R. W., Ruefli, A. A., Lowe, S. W. (January 2002) Apoptosis: A link between cancer genetics and chemotherapy. Cell, 108 (2). pp. 153-164. ISSN 0092-8674

K

Kerr, J. B., Hutt, K. J, Michalak, E. M., Cook, M., Vandenberg, C. J., Liew, S. H., Bouillet, P., Mills, A., Scott, C. L., Findlay, J. K., Strasser, A. (November 2012) DNA Damage-Induced Primordial Follicle Oocyte Apoptosis and Loss of Fertility Require TAp63-Mediated Induction of Puma and Noxa. Molecular Cell, 48 (3). pp. 343-352. ISSN 1097-2765

Kirsch, D. G., Doseff, A., Chau, B. N., Lim, D. S., de Souza-Pinto, N. C., Hansford, R., Kastan, M. B., Lazebnik, Y. A., Hardwick, J. M. (1999) Caspase-3-dependent cleavage of Bcl-2 promotes release of cytochrome c. Journal of Biological Chemistry, 274 (30). pp. 21155-21161. ISSN 0021-9258

Klein, Harry, Gallagher, Joseph, Demesa-Arevalo, Edgar, Abraham-Juárez, María Jazmín, Heeney, Michelle, Feil, Regina, Lunn, John E, Xiao, Yuguo, Chuck, George, Whipple, Clinton, Jackson, David, Bartlett, Madelaine (January 2022) Recruitment of an ancient branching program to suppress carpel development in maize flowers. Proceedings of the National Academy of Sciences of USA, 119 (2). e2115871119-e2115871119. ISSN 0027-8424

Koumenis, C., Alarcon, R., Hammond, E., Sutphin, P., Hoffman, W., Murphy, M., Derr, J., Taya, Y., Lowe, S. W., Kastan, M., Giaccia, A. (February 2001) Regulation of p53 by hypoxia: Dissociation of transcriptional repression and apoptosis from p53-dependent transactivation. Molecular and Cellular Biology, 21 (4). pp. 1297-1310. ISSN 0270-7306

Kulkarni, S., Micci, M. A., Leser, J., Shin, C., Tang, S. C., Fu, Y. Y., Liu, L., Li, Q., Saha, M., Li, C., Enikolopov, G., Becker, L., Rakhilin, N., Anderson, M., Shen, X., Dong, X., Butte, M. J., Song, H., Southard-Smith, E. M., Kapur, R. P., Bogunovic, M., Pasricha, P. J. (May 2017) Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis. Proc Natl Acad Sci U S A, 114 (18). E3709-E3718. ISSN 0027-8424

L

Lalanne, E., Honys, D., Johnson, A., Borner, G. H. H., Lilley, K. S., Dupree, P., Grossniklaus, U., Twell, D. (January 2004) SETH1 and SETH2, two components of the glycosylphosphatidylinositol anchor biosynthetic pathway, are required for pollen germination and tube growth in arabidopsis. Plant Cell, 16 (1). pp. 229-240. ISSN 1040-4651

Lassus, Patrice, Opitz-Araya, Ximena, Lazebnik, Yuri (2002) Requirement for caspase-2 in stress-induced apoptosis before mitochondrial permeabilization. Science, 297 (5585). pp. 1352-1354. ISSN 1095-9203

Lazarev, D., Miller, R. L., Dimango, E., Fu, X. D., Li, H. R., Logan, C. J., Manley, J. L. (May 2014) CFLIP expression is altered in severe corticosteroid-resistant asthma. Genomics Data, 2. pp. 99-104. ISSN 22135960

Lazebnik, Y. (2001) Why do regulators of apoptosis look like bacterial toxins? Current Biology, 11 (19). pp. 767-768. ISSN 0960-9822

Lazebnik, Y. A., Cole, S., Cooke, C. A., Nelson, W. G., Earnshaw, W. C. (1993) Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis. Journal of Cell Biology, 123 (1). pp. 7-22. ISSN 0021-9525

Lazebnik, Y. A., Takahashi, A., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H., Earnshaw, W. C. (1995) Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution. Proc Natl Acad Sci U S A, 92 (20). pp. 9042-9046. ISSN 0027-8424

Lazebnik, Yuri (2002) Can a biologist fix a radio?--Or, what I learned while studying apoptosis. Cancer Cell, 2 (3). pp. 179-182. ISSN 1535-6108

Li, Zhen, Huang, Xiaoqian, Zhan, Huiqing, Zeng, Zhiqiang, Li, Caixia, Spitsbergen, Jan M, Meierjohann, Svenja, Schartl, Manfred, Gong, Zhiyuan (February 2012) Inducible and repressable oncogene-addicted hepatocellular carcinoma in Tet-on xmrk transgenic zebrafish. Journal of Hepatology, 56 (2). pp. 419-425. ISSN 0168-8278

Li, Zhengnian, Ishida, Ryosuke, Liu, Yan, Wang, Jinhua, Li, Yina, Gao, Yang, Jiang, Jie, Che, Jianwei, Sheltzer, Jason M, Robers, Matthew B, Zhang, Tinghu, Westover, Kenneth D, Nabet, Behnam, Gray, Nathanael S (May 2022) Synthesis and Structure-Activity relationships of cyclin-dependent kinase 11 inhibitors based on a diaminothiazole scaffold. European Journal of Medicinal Chemistry, 238. p. 114433. ISSN 0223-5234

Liao, S. C., Hsu, H. W., Chuang, K. L., Huang, Z. Y., Lin, K. T., Hsu, W. H., Chang, K. H., Huang, C. F., Su, C. L. (June 2019) Using the Pleiotropic Characteristics of Curcumin to Validate the Potential Application of a Novel Gene Expression Screening Platform. Nutrients, 11 (6). ISSN 2072-6643

Liao, S. C., Hsu, W. H., Huang, Z. Y., Chuang, K. L., Lin, K. T., Tseng, C. L., Tsai, T. H., Dao, A. H., Su, C. L., Huang, C. F. (December 2019) Bioactivity Evaluation of a Novel Formulated Curcumin. Nutrients, 11 (12). ISSN 2072-6643 (Public Dataset)

Lindemann, R., Newbold, A., Whitecross, K., Cluse, L., Frew, A., Ellis, L., Williams, S., Wiegmans, A., Dear, A., Scott, C., Pelligrini, M., Wei, A., Richon, V., Marks, P., Lowe, S. W., Smyth, M., Johnstone, R. (February 2008) Defining the apoptotic pathways underlying HDAC inhibitor-mediated tumor therapy in vivo. Onkologie, 31 (Suppl.). pp. 69-70. ISSN 0378-584X

Lindemann, R. K., Newbold, A., Whitecross, K. F., Cluse, L. A., Frew, A. J., Ellis, L., Williams, S., Wiegmans, A. P., Dear, A. E., Scott, C. L., Pellegrini, M., Wei, A., Richon, V. M., Marks, P. A., Lowe, S. W., Smyth, M. J., Johnstone, R. W. (May 2007) Analysis of the apoptotic and therapeutic activities of histone deacetylase inhibitors by using a mouse model of B cell lymphoma. Proc Natl Acad Sci U S A, 104 (19). pp. 8071-6. ISSN 0027-8424

Liu, Q. A., Hengartner, M. O. (June 1998) Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans. Cell, 93 (6). pp. 961-72. ISSN 0092-8674 (Print)

Liu, Q. A., Hengartner, M. O. (November 1999) Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6. Current Biology, 9 (22). pp. 1347-50. ISSN 0960-9822 (Print)

Liu, Q. A., Hengartner, M. O. (December 1999) The molecular mechanism of programmed cell death in C. elegans. Annals of the New York Academy of Sciences, 887. pp. 92-104. ISSN 0077-8923 (Print)

Lobo, Anandi, Mishra, Sourav K, Jha, Shilpy, Tiwari, Ankit, Kapoor, Rahul, Sharma, Shivani, Kaushal, Seema, Kiranmai, N Sri, Das, M Rakshitha, Peddinti, Kamal P, Sharma, Shailendra K, Bhardwaj, Nitin, Arora, Samriti, Jain, Deepika, Jain, Ekta, Munjal, Gauri, Shinde, Sayali, Malik, Vipra, Singh, Hena, Varshney, Juhi, Pradhan, Dinesh, Dixit, Mallika, Pattnaik, Niharika, Sharma, Ashish K, Barapatre, Yogesh R, Pradhan, Manas, Satapathy, Kaliprasad, Rath, Debadarshi, Jaiswal, Sunil, Das, Stithi, Khadenga, Chiraranjan, Routa, Sudhasmita, Baisakh, Manas R, Tiwari, Romila, Sampat, Nakul Y, Chakrabarti, Indranil, Parwani, Anil V, Mohanty, Sambit K (January 2024) Evaluation of programmed cell death ligand 1 expression in a contemporary cohort of penile squamous cell carcinoma and its correlation with clinicopathologic and survival parameters: A study of 134 patients. American Journal of Clinical Pathology. aqad107. ISSN 0002-9173

Lowe, S. (November 2002) Roles of oncogenes and tumor suppressor genes in apoptosis. European Journal of Cancer, 38. S15-S15. ISSN 0959-8049

Lowe, S. W., Cepero, E., Evan, G. (November 2004) Intrinsic tumour suppression. Nature, 432 (7015). pp. 307-15. ISSN 1476-4687 (Electronic)

Lowe, S. W., Lin, A. W. (March 2000) Apoptosis in cancer. Carcinogenesis, 21 (3). pp. 485-495. ISSN 0143-3334

Lucs, A. V., Muller, W. J., Muthuswamy, S. K. (January 2010) Shc is required for ErbB2-induced inhibition of apoptosis but is dispensable for cell proliferation and disruption of cell polarity. Oncogene, 29 (2). pp. 174-187. ISSN 0950-9232

Lyons, S. K., Clarke, A. R. (1997) Apoptosis and carcinogenesis. Br Med Bull, 53 (3). pp. 554-69. ISSN 0007-1420 (Print)0007-1420 (Linking)

M

Ma, O., Cai, W. W., Zender, L., Dayaram, T., Shen, J. H., Herron, A. J., Lowe, S. W., Man, T. K., Lau, C. C., Donehower, L. A. (March 2009) MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), Amplified on Chromosome 9, Collaborate with p53 Deficiency in Mouse Osteosarcoma Progression. Cancer Res, 69 (6). pp. 2559-2567. ISSN 0008-5472

Maestro, R., Dei Tos, A. P., Hamamori, Y., Krasnokutsky, S., Sartorelli, V., Kedes, L., Doglioni, C., Beach, D. H., Hannon, G. J. (September 1999) Twist is a potential oncogene that inhibits apoptosis. Genes and Development, 13 (17). pp. 2207-17. ISSN 0890-9369

Matapurkar, A., Lazebnik, Y. (December 2006) Requirement of cytochrome c for apoptosis in human cells. Cell Death Differ, 13 (12). pp. 2062-7. ISSN 1350-9047 (Print)

McCurrach, M. E., Connor, T. M., Knudson, C. M., Korsmeyer, S. J., Lowe, S. W. (March 1997) bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 94 (6). pp. 2345-9. ISSN 0027-8424

McCurrach, M. E., Lowe, S. W. (2001) Methods for studying pro- and antiapoptotic genes in nonimmortal cells. In: Methods in Cell Biology. Methods in Cell Biology, 66 . Academic Press Inc, San Diego, pp. 197-227. ISBN 0091-679X

Mills, A. A. (February 2006) p63: oncogene or tumor suppressor? Curr Opin Genet Dev, 16 (1). pp. 38-44. ISSN 0959-437X (Print)

Mills, J. R., Malina, A., Lee, T., Di Paola, D., Larsson, O., Miething, C., Grosse, F., Tang, H. L., Zannis-Hadjopoulos, M., Lowe, S. W., Pelletier, J. (April 2013) RNAi screening uncovers Dhx9 as a modifier of ABT-737 resistance in an E mu-myc/Bcl-2 mouse model. Blood, 121 (17). pp. 3402-3412. ISSN 0006-4971

Moran, E. (July 1993) Interaction of adenoviral proteins with pRB and p53. Faseb J, 7 (10). pp. 880-5. ISSN 0892-6638 (Print)

Murray, S. A., Zheng, H. W., Gu, L., Xiao, Z. X. J. (March 2003) IGF-1 activates p21 to inhibit UV-induced cell death. Oncogene, 22 (11). pp. 1703-1711. ISSN 0950-9232

N

Nicholson, D. W., Ali, A., Thornberry, N. A., Vaillancourt, J. P., Ding, C. K., Gallant, M., Gareau, Y., Griffin, P. R., Labelle, M., Lazebnik, Y. A. (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature, 376 (6535). pp. 37-43. ISSN 0028-0836

O

Okada, H., Suh, W. K., Jin, J., Woo, M., Du, C., Elia, A., Duncan, G. S., Wakeham, A., Itie, A., Lowe, S. W., Wang, X., Mak, T. W. (May 2002) Generation and characterization of Smac/DIABLO-deficient mice. Molecular and Cellular Biology, 22 (10). pp. 3509-3517. ISSN 0270-7306

Ortiz, Michael V, Ahmed, Saima, Burns, Melissa, Henssen, Anton G, Hollmann, Travis J, MacArthur, Ian, Gunasekera, Shehana, Gaewsky, Lyvia, Bradwin, Gary, Ryan, Jeremy, Letai, Anthony, He, Ying, Naranjo, Arlene, Chi, Yueh-Yun, LaQuaglia, Michael, Heaton, Todd, Cifani, Paolo, Dome, Jeffrey S, Gadd, Samantha, Perlman, Elizabeth, Mullen, Elizabeth, Steen, Hanno, Kentsis, Alex (August 2019) Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms’ tumor. JCI Insight, 4 (15). ISSN 2379-3708

P

Pai, E. L., Vogt, D., Clemente-Perez, A., McKinsey, G. L., Cho, F. S., Hu, J. S., Wimer, M., Paul, A., Fazel Darbandi, S., Pla, R., Nowakowski, T. J., Goodrich, L. V., Paz, J. T., Rubenstein, J. L. R. (January 2019) Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function. Cell Rep, 26 (5). 1157-1173.e5. ISSN 2211-1247

Papazoglu, C., Mills, A. A. (January 2007) p53: At the crossroad between cancer and ageing. Journal of Pathology, 211 (2). pp. 124-133. ISSN 0022-3417

Patterson, S. D., Grossman, J. S., D'Andrea, P., Latter, G. I. (April 1995) Reduced numatrin/B23/nucleophosmin labeling in apoptotic Jurkat T-lymphoblasts. J Biol Chem, 270 (16). pp. 9429-36. ISSN 0021-9258 (Print)

Pawlak, G., Helfman, D. M. (February 2001) Cytoskeletal changes in cell transformation and tumorigenesis. Current Opinion in Genetics & Development, 11 (1). pp. 41-47. ISSN 0959-437X

Pei, L., Wiser, O., Slavin, A., Mu, D., Powers, S., Jan, L. Y., Hoey, T. (June 2003) Oncogenic potential of TASK3 (Kcnk9) depends on K+ channel function. Proceedings of the National Academy of Sciences of the United States of America, 100 (13). pp. 7803-7. ISSN 0027-8424

Pistritto, G., Jost, M., Srinivasula, S. M., Baffa, R., Poyet, J. L., Kari, C., Lazebnik, Y., Rodeck, U., Alnemri, E. S. (2002) Expression and transcriptional regulation of caspase-14 in simple and complex epithelia. Cell Death and Differentiation, 9 (9). pp. 995-991006. ISSN 1350-9047

R

Rao, L., Debbas, M., Sabbatini, P., Hockenbery, D., Korsmeyer, S., White, E. (August 1992) The adenovirus E1A proteins induce apoptosis, which is inhibited by the E1B 19-kDa and Bcl-2 proteins. Proceedings of the National Academy of Sciences of the United States of America, 89 (16). pp. 7742-7746. ISSN 0027-8424

Reginato, M. J., Muthuswamy, S. K. (2006) Illuminating the center: Mechanisms regulating lumen formation and maintenance in mammary morphogenesis. Journal of Mammary Gland Biology and Neoplasia, 11 (3-4). pp. 205-211. ISSN 10833021

Replogle, J. M., Zhou, W., Amaro, A. E., McFarland, J. M., Villalobos-Ortiz, M., Ryan, J., Letai, A., Yilmaz, O., Sheltzer, J., Lippard, S. J., Ben-David, U., Amon, A. (December 2020) Aneuploidy increases resistance to chemotherapeutics by antagonizing cell division. Proc Natl Acad Sci U S A, 117 (48). pp. 30566-30576. ISSN 0027-8424 (Print)0027-8424

Rocha, S., Soengas, M. S., Lowe, S. W., Glanzmann, C., Fabbro, D., Winterhalter, K., Bodis, S., Pruschy, M. (September 2000) Protein kinase C inhibitor and irradiation-induced apoptosis: Relevance of the cytochrome c-mediated caspase-9 death pathway. Cell Growth & Differentiation, 11 (9). pp. 491-499. ISSN 1044-9523

Rodriguez, J., Lazebnik, Y. (1999) Caspase-9 and APAF-1 form an active holoenzyme. Genes & Development, 13 (24). pp. 3179-3184. ISSN 0890-9369

Rodriguez, Joe, Chen, Hsu-Hsin, Lin, Shih-Chieh, Lazebnik, Yuri (February 2000) Caspase Phosphorylation, Cell Death, and Species Variability. Science, 287 (5457). p. 1363.

Ryu, S., Lin, S. c., Ugel, N., Antoniotti, M., Mishra, B. (June 2008) Mathematical modeling of the formation of apoptosome in intrinsic pathway of apoptosis. Systems and Synthetic Biology, 2 (1). pp. 49-66.

S

Samuelson, A. V., Lowe, S. W. (October 1997) Selective induction of p53 and chemosensitivity in RB-deficient cells by E1A mutants unable to bind the RB-related proteins. Proceedings of the National Academy of Sciences, 94 (22). pp. 12094-9. ISSN 0027-8424 (Print)

Samuelson, A. V., Narita, M., Chan, H. M., Jin, J., de Stanchina, E., McCurrach, M. E., Narita, M., Fuchs, M., Livingston, D. M., Lowe, S. W. (June 2005) p400 is required for E1A to promote apoptosis. J Biol Chem, 280 (23). pp. 21915-23. ISSN 0021-9258 (Print)

Schmitt, C. A., Lowe, S. W. (January 1999) Apoptosis and therapy. Journal of Pathology, 187 (1). pp. 127-37. ISSN 0022-3417 (Print)

Schmitt, C. A., Lowe, S. W. (April 2001) Apoptosis is critical for drug response in vivo. Drug Resistance Updates, 4 (2). pp. 132-134. ISSN 1368-7646

Schmitt, C. A., McCurrach, M. E., de Stanchina, E., Wallace-Brodeur, R. R., Lowe, S. W. (October 1999) INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53. Genes and Development, 13 (20). pp. 2670-7. ISSN 0890-9369 (Print)

Schmitt, C. A., Yang, M., Fridman, J. S., Baranov, E., Hoffman, R. M., Lowe, S. W. (November 2001) Myc-driven lymphomas respond with both apoptosis and senescence to anticancer treatment in vivo. Blood, 98 (11). 172B-172B. ISSN 0006-4971

Schwertassek, U., Buckley, D. A., Xu, C. F., Lindsay, A. J., McCaffrey, M. W., Neubert, T. A., Tonks, N. K. (June 2010) Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis. Febs Journal, 277 (11). pp. 2463-2473. ISSN 1742-464X

Sendoel, A., Kohler, I., Fellmann, C., Lowe, S. W., Hengartner, M. O. (June 2010) HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase. Nature, 465 (7298). 577-U69. ISSN 0028-0836

Sierra, A., Encinas, J. M., Deudero, J. J. P., Chancey, J. H., Enikolopov, G. N., Overstreet-Wadiche, L. S., Tsirka, S. E., Maletic-Savatic, M. (October 2010) Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis. Cell Stem Cell, 7 (4). pp. 483-495.

Simhal, Anish K, Maclachlan, Kylee H, Elkin, Rena, Zhu, Jiening, Norton, Larry, Deasy, Joseph O, Oh, Jung Hun, Usmani, Saad Z, Tannenbaum, Allen (November 2023) Gene interaction network analysis in multiple myeloma detects complex immune dysregulation associated with shorter survival. Blood Cancer Journal, 13 (1). p. 175. ISSN 2044-5385

Simhal, Anish Kumar, Maclachlan, Kylee H, Usmani, Saad Z, Norton, Larry, Deasy, Joseph O, Oh, Jung Hun, Tannenbaum, Allen (November 2023) Network Modeling of Apoptosis-Related Genes Reveal a High-Risk Cluster in Multiple Myeloma. In: UNSPECIFIED.

Simpson, D. R. (February 2010) Regulation of Myc-induced apoptosis in the mammary epithelia. PhD thesis, Cold Spring Harbor Laboratory.

Soengas, M. S., Alarcon, R. M., Yoshida, H., Giaccia, A. J., Hakem, R., Mak, T. W., Lowe, S. W. (April 1999) Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition. Science, 284 (5411). pp. 156-9. ISSN 0036-8075 (Print)

Soengas, M. S., Capodieci, P., Polsky, D., Mora, J., Esteller, M., Opitz-Araya, X., McCombie, R., Herman, J. G., Gerald, W. L., Lazebnik, Y. A., Cordon-Cardo, C., Lowe, S. W. (2001) Inactivation of the apoptosis effector Apaf-1 in malignant melanoma. Nature, 409 (6817). pp. 207-211. ISSN 0028-0836

Soengas, M. S., Lowe, S. W. (May 2003) Apoptosis and melanoma chemoresistance. Oncogene, 22 (20). pp. 3138-3151. ISSN 0950-9232

Soengas, M. S., Lowe, S. W. (December 2000) p53 and p73: seeing double? Nature Genetics, 26 (4). pp. 391-392. ISSN 1061-4036

Song, Dongyan, Cen, Yuxin, Qian, Zhe, Wu, Xiaoli S, Rivera, Keith, Wee, Tse-Luen, Demerdash, Osama E, Chang, Kenneth, Pappin, Darryl, Vakoc, Christopher R, Tonks, Nicholas K (November 2024) PTPN23-dependent ESCRT machinery functions as a cell death checkpoint. Nature Communications, 15 (1). p. 10364. ISSN 2041-1723 (Public Dataset)

Spector, M. S., Desnoyers, S., Hoeppner, D. J., Hengartner, M. O. (February 1997) Interaction between the C. elegans cell-death regulators CED-9 and CED-4. Nature, 385 (6617). pp. 653-6. ISSN 0028-0836 (Print)

Spector, M. S., Hengartner, M. O. (1997) Orderly dismantling of a cell. Apoptosis, 2 (3). pp. 343-6. ISSN 1360-8185 (Print)

Srinivasula, S. M., Ahmad, M., Guo, Y., Zhan, Y., Lazebnik, Y., Fernandes-Alnemri, T., Alnemri, E. S. (1999) Identification of an endogenous dominant-negative short isoform of caspase-9 that can regulate apoptosis. Cancer Research, 59 (5). pp. 999-1002. ISSN 0008-5472

Stegh, A. H., Kim, H., Bachoo, R. M., Forloney, K. L., Zhang, J., Schulze, H., Park, K., Hannon, G. J., Yuan, J. Y., Louis, D. N., DePinho, R. A., Chin, L. (January 2007) Bcl2L12 inhibits post-mitochondrial apoptosis signaling in glioblastoma. Genes Dev, 21 (1). pp. 98-111. ISSN 0890-9369

Su, H. P., Brugnera, E., Van Criekinge, W., Smits, E., Hengartner, M., Bogaert, T., Ravichandran, K. S. (March 2000) Identification and characterization of a dimerization domain in CED-6, an adapter protein involved in engulfment of apoptotic cells. Journal of Biological Chemistry, 275 (13). pp. 9542-9549. ISSN 0021-9258

Svingen, P. A., Karp, J. E., Krajewski, S., Mesner, P. W., Gore, S. D., Burke, P. J., Reed, J. C., Lazebnik, Y. A., Kaufmann, S. H. (2000) Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia. Blood, 96 (12). pp. 3922-3931. ISSN 0006-4971

T

Takahashi, A., Alnemri, E. S., Lazebnik, Y. A., Fernandes-Alnemri, T., Litwack, G., Moir, R. D., Goldman, R. D., Poirier, G. G., Kaufmann, S. H., Earnshaw, W. C. (1996) Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis. Proc Natl Acad Sci U S A, 93 (16). pp. 8395-8400. ISSN 0027-8424

Tamori, Y., Bialucha, C. U., Tian, A. G., Kajita, M., Huang, Y. C., Norman, M., Harrison, N., Poulton, J., Ivanovitch, K., Disch, L., Liu, T., Deng, W. M., Fujita, Y. (2010) Involvement of Lgl and mahjong/VprBP in cell competition. PLoS biology, 8 (7).

Tansey, W. P. (July 2004) Death, destruction, and the proteasome. N Engl J Med, 351 (4). pp. 393-4. ISSN 1533-4406 (Electronic)

Tarumoto, Y., Lin, S., Wang, J., Milazzo, J. P., Xu, Y., Lu, B., Yang, Z., Wei, Y., Polyanskaya, S., Wunderlich, M., Gray, N. S., Stegmaier, K., Vakoc, C. R. (November 2019) Salt-Inducible Kinase inhibition suppresses acute myeloid leukemia progression in vivo. Blood. ISSN 0006-4971

Thornberry, N. A., Lazebnik, Y. (1998) Caspases: enemies within. Science, 281 (5381). pp. 1312-1316. ISSN 0036-8075

V

Vasudevan, A., Baruah, P.S., Smith, J.C., Wang, Z., Sayles, N. M., Andrews, P., Kendall, J., Leu, J., Chunduri, N.K., Levy, D., Wigler, M., Storchova, Z., Sheltzer, J. M. (February 2020) Single-Chromosomal Gains Can Function as Metastasis Suppressors and Promoters in Colon Cancer. Developmental Cell, 52 (4). pp. 413-428. ISSN 1534-5807

Vaughn, D. E., Rodriguez, J., Lazebnik, Y., Joshua-Tor, L. (1999) Crystal structure of Apaf-1 caspase recruitment domain: an alpha-helical Greek key fold for apoptotic signaling. Journal of Molecular Biology, 293 (3). pp. 439-447. ISSN 0022-2836 (Public Dataset)

W

Walsh, T., Pierce, S. B., Lenz, D. R., Brownstein, Z., Dagan-Rosenfeld, O., Shahin, H., Roeb, W., McCarthy, S. E., Nord, A. S., Gordon, C. R., Ben-Neriah, Z., Sebat, J., Kanaan, M., Lee, M. K., Frydman, M., King, M. C., Avraham, K. B. (July 2010) Genomic Duplication and Overexpression of TJP2/ZO-2 Leads to Altered Expression of Apoptosis Genes in Progressive Nonsyndromic Hearing Loss DFNA51. American Journal of Human Genetics, 87 (1). 101-109 .

Wang, E., Kawaoka, S., Roe, J. S., Shi, J., Hohmann, A. F., Xu, Y., Bhagwat, A. S., Suzuki, Y., Kinney, J. B., Vakoc, C. R. (April 2015) The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer. Elife, 4. ISSN 2050-084X (Electronic)2050-084X (Linking)

Wang, G. H., Krishnamurthy, K., Tangpisuthipongsa, D. (May 2011) Protection of murine neural progenitor cells by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin in the low nanomolar concentration range. Journal of Neurochemistry, 117 (4). pp. 703-711. ISSN 0022-3042

Wang, Y., Leonard, M. K., Snyder, D. E., Fisher, M. L., Eckert, R. L., Kaetzel, D. M. (August 2019) NME1 Drives Expansion of Melanoma Cells with Enhanced Tumor Growth and Metastatic Properties. Mol Cancer Res, 17 (8). pp. 1665-1674. ISSN 1541-7786

Wang, Bor-Shuen, Bernardez Sarria, Maria Sol, An, Xu, He, Miao, Alam, Nazia M, Prusky, Glen T, Crair, Michael C, Huang, Z Josh (February 2021) Retinal and Callosal Activity-Dependent Chandelier Cell Elimination Shapes Binocularity in Primary Visual Cortex. Neuron, 109 (3). 502-515.e7. ISSN 0896-6273

Wendel, H. G., De Stanchina, E., Fridman, J. S., Malina, A., Ray, S., Kogan, S., Cordon-Cardo, C., Pelletier, J., Lowe, S. W. (March 2004) Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. Nature, 428 (6980). pp. 332-7. ISSN 1476-4687 (Electronic)

Wendel, H. G., Lowe, S. W. (July 2004) Reversing drug resistance in vivo. Cell Cycle, 3 (7). pp. 847-9. ISSN 1551-4005 (Electronic)

White, E., Sabbatini, P., Debbas, M., Wold, W. S., Kusher, D. I., Gooding, L. R. (June 1992) The 19-kilodalton adenovirus E1B transforming protein inhibits programmed cell death and prevents cytolysis by tumor necrosis factor alpha. Mol Cell Biol, 12 (6). pp. 2570-80. ISSN 0270-7306 (Print)0270-7306 (Linking)

Wissing, D., Mouritzen, H., Egeblad, M., Poirier, G. G., Jaattela, M. (May 1997) Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis. Proceedings of the National Academy of Sciences of the United States of America, 94 (10). pp. 5073-7. ISSN 0027-8424 (Print)0027-8424

Wu, C., Liu, T., Chen, W., Oka, S., Fu, C. X., Jain, M. R., Parrott, A. M., Baykal, A. T., Sadoshima, J., Li, H. (October 2010) Redox Regulatory Mechanism of Transnitrosylation by Thioredoxin. Molecular & Cellular Proteomics, 9 (10). pp. 2262-2275. ISSN 1535-9476

Wu, Q., Jackson, D. (January 2018) Detection of MAPK3/6 Phosphorylation During Hypersensitive Response (HR)-Associated Programmed Cell Death in Plants. Methods Mol Biol, 1743. pp. 153-161. ISSN 1064-3745

Y

Ye, S., Ponz-Sarvise, M., Chang, S. S., Chang, W. C., Chen, C. H., Hsu, J. L., Hung, M. C. (April 2015) Proteasome inhibition enhances the killing effect of BikDD gene therapy. American Journal of Translational Research, 7 (2). pp. 319-327. ISSN 19438141

Z

Zheng, T. S., Hunot, S., Kuida, K., Momoi, T., Srinivasan, A., Nicholson, D. W., Lazebnik, Y., Flavell, R. A. (2000) Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nature Medicine, 6 (11). pp. 1241-1247. ISSN 1078-8956

Zilfou, J. T., Spector, M. S., Lowe, S. W. (November 2005) Slugging it out: fine tuning the p53-PUMA death connection. Cell, 123 (4). pp. 545-8. ISSN 0092-8674 (Print)