Items where Community is "Mills lab"

Paper

Fisher, Matthew L, Balinth, Seamus, Hwangbo, Yon, Wu, Caizhi, Ballon, Carlos, Goldberg, Gary L, Mills, Alea A (August 2023) Cancer-associated fibroblasts promote cancer stemness by inducing expression of the chromatin-modifying protein CBX4 in squamous cell carcinoma. Carcinogenesis, 44 (6). pp. 485-496. ISSN 0143-3334

Brina, Daniela, Ponzoni, Adele, Troiani, Martina, Calì, Bianca, Pasquini, Emiliano, Attanasio, Giuseppe, Mosole, Simone, Mirenda, Michela, D'Ambrosio, Mariantonietta, Colucci, Manuel, Guccini, Ilaria, Revandkar, Ajinkya, Alajati, Abdullah, Tebaldi, Toma, Donzel, Deborah, Lauria, Fabio, Parhizgari, Nahjme, Valdata, Aurora, Maddalena, Martino, Calcinotto, Arianna, Bolis, Marco, Rinaldi, Andrea, Barry, Simon, Rüschoff, Jan Hendrik, Sabbadin, Marianna, Sumanasuriya, Semini, Crespo, Mateus, Sharp, Adam, Yuan, Wei, Grinu, Mathew, Boyle, Alexandra, Miller, Cynthia, Trotman, Lloyd, Delaleu, Nicolas, Fassan, Matteo, Moch, Holger, Viero, Gabriella, de Bono, Johann, Alimonti, Andrea (August 2023) The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells. Nature Cancer, 4 (8). pp. 1102-1121. ISSN 2662-1347 (Public Dataset)

Shrestha, Padmina, Jaganathan, Anbalagan, Huilgol, Dhananjay, Ballon, Carlos, Hwangbo, Yon, Mills, Alea A (January 2023) Chd5 regulates the transcription factor Six3 to promote neuronal differentiation. Stem Cells. sxad002. ISSN 1066-5099 (Public Dataset)

Sun, Xueqin, Klingbeil, Olaf, Lu, Bin, Wu, Caizhi, Ballon, Carlos, Ouyang, Meng, Wu, Xiaoli S, Jin, Ying, Hwangbo, Yon, Huang, Yu-Han, Somerville, Tim DD, Chang, Kenneth, Park, Jung, Chung, Taemoon, Lyons, Scott K, Shi, Junwei, Vogel, Hannes, Schulder, Michael, Vakoc, Christopher R, Mills, Alea A (December 2022) BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network. Nature. ISSN 0028-0836

Fisher, Matthew L, Balinth, Seamus, Mills, Alea A (September 2022) ΔNp63α in cancer: importance and therapeutic opportunities. Trends in Cell Biology. S0962-8924(22)00194. ISSN 0962-8924

Balinth, Seamus, Fisher, Matthew L, Hwangbo, Yon, Wu, Caizhi, Ballon, Carlos, Sun, Xueqin, Mills, Alea A (July 2022) EZH2 regulates a SETDB1/ΔNp63α axis via RUNX3 to drive a cancer stem cell phenotype in squamous cell carcinoma. Oncogene. ISSN 0950-9232 (Public Dataset)

Stefanski, Heather E, Xing, Yan, Nicholls, Jemma, Jonart, Leslie, Goren, Emily, Taylor, Patricia A, Mills, Alea A, Riddle, Megan, McGrath, John, Tolar, Jakub, Hollander, Georg A, Blazar, Bruce R (January 2022) P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss. PLoS One, 17 (1). ISSN 1932-6203

Fisher, Matthew L, Balinth, Seamus, Hwangbo, Yon, Wu, Caizhi, Ballon, Carlos, Wilkinson, John E, Goldberg, Gary L, Mills, Alea A (October 2021) BRD4 REGULATES TRANSCRIPTION FACTOR ∆Np63αTO DRIVE A CANCER STEM CELL PHENOTYPE IN SQUAMOUS CELL CARCINOMAS. Cancer Research. canres.0707.2021-canres.0707.2021. ISSN 0008-5472

Fisher, M. L., Balinth, S., Mills, A. A. (September 2020) p63-related signaling at a glance. J Cell Sci, 133 (17). ISSN 0021-9533 (Print)0021-9533

Rein, B., Tan, T., Yang, F., Wang, W., Williams, J., Zhang, F., Mills, A., Yan, Z. (February 2020) Reversal of Synaptic and Behavioral Deficits in a 16p11.2 Duplication Mouse Model via Restoration of the GABA Synapse Regulator Npas4. Mol Psychiatry. ISSN 1359-4184

Hershlag, A., Peyser, A., Bristow, S. L., Puig, O., Pollock, A., Niknazar, M., Mills, A. A. (December 2019) The potential impact of tumor suppressor genes on human gametogenesis: a case-control study. J Assist Reprod Genet. ISSN 1058-0468

Wang, Y., Leonard, M. K., Snyder, D. E., Fisher, M. L., Eckert, R. L., Kaetzel, D. M. (August 2019) NME1 Drives Expansion of Melanoma Cells with Enhanced Tumor Growth and Metastatic Properties. Mol Cancer Res, 17 (8). pp. 1665-1674. ISSN 1541-7786

Lu, H. C., Pollack, H., Lefante, J. J., Mills, A. A., Tian, D. (December 2018) Altered sleep architecture, rapid eye movement (REM) sleep, and neural oscillation in a mouse model of human chromosome 16p11.2 microdeletion. Sleep, 42 (3). ISSN 0161-8105

Hwang, D. W., Jaganathan, A., Shrestha, P., Jin, Y., El-Amine, N., Wang, S. H., Hammell, M., Mills, A. A. (August 2018) Chromatin-mediated translational control is essential for neural cell fate specification. Life Sci Alliance, 1 (4). e201700016. ISSN 2575-1077

Lu, H. C., Mills, A. A., Tian, D. (March 2018) Altered synaptic transmission and maturation of hippocampal CA1 neurons in a mouse model of human chr16p11.2 microdeletion. J Neurophysiol, 119 (3). pp. 1005-1018. ISSN 0022-3077

Peyser, A., Bristow, S. L., Puig, O., Pollock, A., Mills, A., Niknazar, M., Hershlag, A. (September 2017) Do mutations in CHD5 cause male infertility? Fertility and Sterility, 108 (3, Sup). e140-e141. ISSN 0015-0282

Peyser, A., Bristow, S. L., Puig, O., Pollock, A., Mills, A., Niknazar, M., Hershlag, A. (September 2017) Do tumor suppressor genes (TSG) play a role in diminished ovarian reserve (DOR). Fertility and Sterility, 108 (3, Sup). e220. ISSN 0015-0282

Taniguchi, Y., Kawata, M., Ho Chang, S., Mori, D., Okada, K., Kobayashi, H., Sugita, S., Hosaka, Y., Inui, H., Taketomi, S., Yano, F., Ikeda, T., Akiyama, H., Mills, A. A., Chung, U. I., Tanaka, S., Kawaguchi, H., Saito, T. (March 2017) Regulation of Chondrocyte Survival in Mouse Articular Cartilage by p63. Arthritis and Rheumatology, 69 (3). pp. 598-609. ISSN 2326-5205

Mills, A. A. (January 2017) The Chromodomain Helicase DNA-Binding Chromatin Remodelers: Family Traits that Protect from and Promote Cancer. Cold Spring Harb Perspect Med. ISSN 2157-1422 (Electronic)2157-1422 (Linking)

Kawata, M., Taniguchi, Y., Mori, D., Yano, F., Ohba, S., Chung, U. I., Shimogori, T., Mills, A. A., Tanaka, S., Saito, T. (2017) Different regulation of limb development by p63 transcript variants. PLoS One, 12 (3). e0174122. ISSN 1932-6203

Zhu, J., Peng, T., Chang, Y., Layton, E., Sun, S. J., Phasouk, K., Johnston, C., Halford, W. P., Wald, A., Corey, L. (May 2016) Tissue resident memory CD8 T cells augment innate immunity for tissue-wide antiviral protection. Journal of Immunology, 196 (Supple). 148.7. ISSN 0022-17671550-6606

Liu, Y., Chen, C., Xu, Z., Scuoppo, C., Rillahan, C. D., Gao, J., Spitzer, B., Bosbach, B., Kastenhuber, E. R., Baslan, T., Ackermann, S., Cheng, L., Wang, Q., Niu, T., Schultz, N., Levine, R. L., Mills, A. A., Lowe, S. W. (March 2016) Deletions linked to TP53 loss drive cancer through p53-independent mechanisms. Nature, 531 (7595). pp. 471-475. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Zepeda-Mendoza, C. J., Mukhopadhyay, S., Wong, E. S., Harder, N., Splinter, E., de Wit, E., Eckersley-Maslin, M. A., Ried, T., Eils, R., Rohr, K., Mills, A., de Laat, W., Flicek, P., Sengupta, A. M., Spector, D. L. (November 2015) Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2. BMC Genomics, 16 (1). p. 982. ISSN 1471-2164 (Electronic)1471-2164 (Linking)

Brunner, D., Kabitzke, P., He, D., Cox, K., Thiede, L., Hanania, T., Sabath, E., Alexandrov, V., Saxe, M., Peles, E., Mills, A., Spooren, W., Ghosh, A., Feliciano, P., Benedetti, M., Luo Clayton, A., Biemans, B. (August 2015) Comprehensive Analysis of the 16p11.2 Deletion and Null Cntnap2 Mouse Models of Autism Spectrum Disorder. PLoS One, 10 (8). e0134572. ISSN 1932-6203 (Electronic)1932-6203 (Linking)

Yu, C., Horev, G., Rubin, N., Derdikman, D., Haidarliu, S., Ahissar, E. (March 2015) Coding of object location in the vibrissal thalamocortical system. Cereb Cortex, 25 (3). pp. 563-77. ISSN 1460-2199 (Electronic)1047-3211 (Linking)

Ellegood, J., Anagnostou, E., Babineau, B. A., Crawley, J. N., Lin, L., Genestine, M., DiCicco-Bloom, E., Lai, J. K., Foster, J. A., Penagarikano, O., Geschwind, D. H., Pacey, L. K., Hampson, D. R., Laliberte, C. L., Mills, A. A., Tam, E., Osborne, L. R., Kouser, M., Espinosa-Becerra, F., Xuan, Z., Powell, C. M., Raznahan, A., Robins, D. M., Nakai, N., Nakatani, J., Takumi, T., van Eede, M. C., Kerr, T. M., Muller, C., Blakely, R. D., Veenstra-VanderWeele, J., Henkelman, R. M., Lerch, J. P. (February 2015) Clustering autism: using neuroanatomical differences in 26 mouse models to gain insight into the heterogeneity. Mol Psychiatry, 20 (1). pp. 118-125. ISSN 1359-4184

Ellegood, J., Anagnostou, E., Babineau, B. A., Crawley, J. N., Lin, L., Genestine, M., DiCicco-Bloom, E., Lai, J. K., Foster, J. A., Penagarikano, O., Geschwind, D. H., Pacey, L. K., Hampson, D. R., Laliberte, C. L., Mills, A. A., Tam, E., Osborne, L. R., Kouser, M., Espinosa-Becerra, F., Xuan, Z., Powell, C. M., Raznahan, A., Robins, D. M., Nakai, N., Nakatani, J., Takumi, T., van Eede, M. C., Kerr, T. M., Muller, C., Blakely, R. D., Veenstra-VanderWeele, J., Henkelman, R. M., Lerch, J. P. (February 2015) 3D visualization of the regional differences. Mol Psychiatry, 20 (1). p. 1. ISSN 1359-4184

Tian, D., Stoppel, L. J., Heynen, A. J., Lindemann, L., Jaeschke, G., Mills, A. A., Bear, M. F. (January 2015) Contribution of mGluR5 to pathophysiology in a mouse model of human chromosome 16p11.2 microdeletion. Nature Neuroscience, 18. pp. 182-184. ISSN 1097-6256

Yu, S., Yehia, G., Wang, J., Stypulkowski, E., Sakamori, R., Jiang, P., Hernandez-Enriquez, E. B., Tran, T. S., Bonder, E. M., Guo, W., Gao, N. (September 2014) Global Ablation of Mouse Rab11a Impairs Early Embryogenesis and Matrix Metalloproteinase Secretion. Journal of Biological Chemistry, 289 (46). pp. 32030-32043. ISSN 0021-9258

Li, Wanhe, Mills, Alea A. (August 2014) Architects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromes. Epigenomics, 6 (4). pp. 381-95. ISSN 1750-192x

Li, W., Wu, J., Kim, S. Y., Zhao, M., Hearn, S. A., Zhang, M. Q., Meistrich, M. L., Mills, A. A. (May 2014) Chd5 orchestrates chromatin remodelling during sperm development. Nature Communications, 5. p. 3812. ISSN 20411723

Vestin, A., Mills, A. A. (October 2013) The tumor suppressor Chd5 is induced during neuronal differentiation, in the developing mouse brain. Gene Expression Patterns, 13 (8). pp. 482-489. ISSN 1872-7298 (Electronic)1567-133X (Linking)

Ramsey, M. R., Wilson, C., Ory, B., Rothenberg, S. M., Faquin, W., Mills, A. A., Ellisen, L. W. (August 2013) FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma. Journal of Clinical Investigation, 123 (8). pp. 3525-3538. ISSN 0021-9738

Kim, S. Y., Cordeiro, M. H., Serna, V. A., Ebbert, K., Butler, L. M., Sinha, S., Mills, A. A., Woodruff, T. K., Kurita, T. (August 2013) Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network. Cell Death and Differentiation, 20 (8). pp. 987-997.

Laronda, Monica M., Unno, Kenji, Ishi, Kazutomo, Serna, Vanida A., Butler, Lindsey M., Mills, Alea A., Orvis, Grant D., Behringer, Richard R., Deng, Chuxia, Sinha, Satrajit, Kurita, Takeshi (July 2013) Diethylstilbestrol induces vaginal adenosis by disrupting SMAD/RUNX1-mediated cell fate decision in the Müllerian duct epithelium. Developmental Biology, 381 (1). pp. 5-16. ISSN 0012-1606

Park, E., Kim, H., Kim, J. M., Primack, B., Vidal-Cardenas, S., Xu, Y., Price, B. D., Mills, A. A., D’Andrea, A. D. (June 2013) FANCD2 Activates Transcription of TAp63 and Suppresses Tumorigenesis. Molecular Cell, 50 (6). pp. 908-918. ISSN 1097-2765

Vernersson Lindahl, E., Garcia, E. L., Mills, A. A. (June 2013) An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. American Journal of Medical Genetics Part A, 161 (8). pp. 1961-1971. ISSN 1552-4825

Kim, M. K., Kim, S. Y. (February 2013) Ascorbic acid enhances the generation of germline chimeras from C57BL/6 ES cells using tetraploid complementation. Transgenic Research, 22 (1). pp. 222-223. ISSN 0962-8819

Paul, S., Kuo, A., Schalch, T., Vogel, H., Joshua-Tor, L., McCombie, W. R., Gozani, O., Hammell, M., Mills, A. A. (January 2013) Chd5 Requires PHD-Mediated Histone 3 Binding for Tumor Suppression. Cell Reports, 3 (1). pp. 92-102. ISSN 2211-1247 (Public Dataset)

Kerr, J. B., Hutt, K. J, Michalak, E. M., Cook, M., Vandenberg, C. J., Liew, S. H., Bouillet, P., Mills, A., Scott, C. L., Findlay, J. K., Strasser, A. (November 2012) DNA Damage-Induced Primordial Follicle Oocyte Apoptosis and Loss of Fertility Require TAp63-Mediated Induction of Puma and Noxa. Molecular Cell, 48 (3). pp. 343-352. ISSN 1097-2765

Nemajerova, A., Kim, S. Y., Petrenko, O., Moll, U. M. (August 2012) Two-factor reprogramming of somatic cells to pluripotent stem cells reveals partial functional redundancy of Sox2 and Klf4. Cell Death and Differentiation, 19 (8). pp. 1268-1276. ISSN 1350-9047

Stadtfeld, M., Apostolou, E., Ferrari, F., Choi, J., Walsh, R. M., Chen, T., Oi, S., Kim, S. Y., Bestor, T., Shioda, T., Park, P. J., Hochedlinger, K. (March 2012) Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nature Genetics, 44. pp. 398-405. ISSN 10614036 (ISSN)

Horev, G., Saig, A., Knutsen, P. M., Pietr, M., Yu, C. X., Ahissar, E. (November 2011) Motor-sensory convergence in object localization: a comparative study in rats and humans. Philosophical Transactions of the Royal Society B-Biological Sciences, 366 (1581). pp. 3070-3076. ISSN 0962-8436

Horev, G., Ellegood, J., Lerch, J. P., Son, Y. E., Muthuswamy, L., Vogel, H., Krieger, A. M., Buja, A., Henkelman, R. M., Wigler, M. H., Mills, A. A. (October 2011) Dosage-dependent phenotypes in models of 16p11.2 lesions found in autism. Proceedings of the National Academy of Sciences of the United States of America, 108 (41). pp. 17076-81. ISSN 0027-8424

Keyes, W. M. , Pecoraro, M., Aranda, V., Vernersson-Lindahl, E., Li, W., Vogel, H., Guo, X., Garcia, E. L., Michurina, T. V., Enikolopov, G. N., Muthuswamy, S. K., Mills, A. A. (February 2011) DeltaNp63alpha Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis. Cell Stem Cell, 8 (2). pp. 164-76. ISSN 1875-9777 (Electronic)

Mills, A. A. (October 2010) Throwing the cancer switch: reciprocal roles of polycomb and trithorax proteins. Nat Rev Cancer, 10 (10). pp. 669-82. ISSN 1474-1768 (Electronic) 1474-175X (Linking)

Moretti, F., Marinari, B., Iacono, N. L., Botti, E., Giunta, A., Spallone, G., Garaffo, G., Vernersson-Lindahl, E., Merlo, G., Mills, A. A., Ballaro, C., Alema, S., Chimenti, S., Guerrini, L., Costanzo, A. (May 2010) A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. Journal of Clinical Investigation, 120 (5). pp. 1570-1577.

Moretti, F., Spallone, G., Botti, E., Giunta, A., Lo Iacono, N., Merlo, G., Mills, A. A., Alema, S., Chimenti, S., Guerrini, L., Costanzo, A. (April 2010) p63 and IRF6 are components of a common molecular pathway disrupted in ectodermal dysplasias. Journal of Investigative Dermatology, 130. p. 626. ISSN 0022-202X

Vernersson-Lindahl, E., Mills, A. A. (March 2010) ΔNp73β puts the brakes on DNA repair. Genes Dev, 24 (6). pp. 517-20. ISSN 1549-5477 (Electronic) 0890-9369 (Linking)

Guo, X., Keyes, W. M., Papazoglu, C., Zuber, J., Li, W., Lowe, S. W., Vogel, H., Mills, A. A. (December 2009) TAp63 induces senescence and suppresses tumorigenesis in vivo. Nat Cell Biol, 11 (12). 1451–1457.

Boles, M. K., Wilkinson, B. M., Maxwell, A., Lai, L., Mills, A. A., Nishijima, I., Salinger, A. P., Moskowitz, I., Hirschi, K. K., Liu, B., Bradley, A., Justice, M. J. (March 2009) A mouse chromosome 4 balancer ENU-mutagenesis screen isolates eleven lethal lines. BMC Genet, 10 (1). p. 12.

Bohland, Jason W, Wu, Caizhi, Barbas, Helen, Bokil, Hemant, Bota, Mihail, Breiter, Hans C, Cline, Hollis T, Doyle, John C, Freed, Peter J, Greenspan, Ralph J, Haber, Suzanne N, Hawrylycz, Michael, Herrera, Daniel G, Hilgetag, Claus C, Huang, Z Josh, Jones, Allan, Jones, Edward G, Karten, Harvey J, Kleinfeld, David, Kotter, Rolf, Lester, Henry A, Lin, John M, Mensh, Brett D, Mikula, Shawn, Panksepp, Jaak, Price, Joseph L, Safdieh, Joseph, Saper, Clifford B, Schiff, Nicholas D, Schmahmann, Jeremy D, Stillman, Bruce W, Svoboda, Karel, Swanson, Larry W, Toga, Arthur W, Essen, David C Van, Watson, James D, Mitra, Partha P (January 2009) A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale. PLoS Computational Biology. (Submitted)

Stark, K. L., Xu, B., Bagchi, A., Lai, W. S., Liu, H., Hsu, R., Wan, X., Pavlidis, P., Mills, A. A., Karayiorgou, M., Gogos, J. A. (June 2008) Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model. Nat Genet, 40 (6). pp. 751-760.

Bagchi, A., Mills, A. A. (April 2008) The quest for the 1p36 tumor suppressor. Cancer Res, 68 (8). pp. 2551-6.

Lo Iacono, N., Mantero, S., Chiarelli, A., Garcia, E. L., Mills, A. A., Morasso, M. I., Costanzo, A., Levi, G., Guerrini, L., Merlo, G. R. (April 2008) Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects. Development, 135 (7). pp. 1377-1388. ISSN 0950-1991

Suzuki, K., Haraguchi, R., Ogata, T., Barbieri, O., Alegria, O., Vieux-Rochas, M., Nakagata, N., Ito, M., Mills, A. A., Kurita, T., Levi, G., Yamada, G. (January 2008) Abnormal urethra formation in mouse models of Split-hand/split-foot malformation type 1 and type 4. Eur J Hum Genet, 16 (1). pp. 36-44.

Mignone, J. L., Roig-Lopez, J. L., Fedtsova, N., Schones, D. E., Manganas, L. N., Maletic-Savatic, M., Keyes, W. M., Mills, A. A., Gleiberman, A., Zhang, M. Q., Enikolopov, G. N. (September 2007) Neural Potential of a Stem Cell Population in the Hair Follicle. Cell Cycle, 6 (17). 2161 - 2170 . ISSN 1551-4005 (Electronic)

Guo, X. C., Mills, A. A. (February 2007) p63, cellular senescence and tumor development. Cell Cycle, 6 (3). pp. 305-11. ISSN 1538-4101

Papazoglu, C., Mills, A. A. (January 2007) p53: At the crossroad between cancer and ageing. Journal of Pathology, 211 (2). pp. 124-133. ISSN 0022-3417

Bagchi, A., Papazoglu, C., Wu, Y., Capurso, D., Brodt, M., Francis, D., Bredel, M., Vogel, H., Mills, A. A. (2007) CHD5 Is a Tumor Suppressor at Human 1p36. Cell, 128 (3). pp. 459-475.

Carroll, D. K., Carroll, J. S., Leong, C. O., Cheng, F., Brown, M., Mills, A. A., Brugge, J. S., Ellisen, L. W. (June 2006) p63 regulates an adhesion programme and cell survival in epithelial cells. Nature Cell Biology, 8 (6). pp. 551-561. ISSN 14657392

Keyes, W. M., Vogel, H., Koster, M. I., Guo, X., Qi, Y., Petherbridge, K. M., Roop, D. R., Bradley, A., Mills, A. A. (May 2006) p63 heterozygous mutant mice are not prone to spontaneous or chemically induced tumors. Proc Natl Acad Sci U S A, 103 (22). pp. 8435-40. ISSN 0027-8424 (Print)

Keyes, W. M., Mills, A. A. (February 2006) p63: a new link between senescence and aging. Cell Cycle, 5 (3). pp. 260-265. ISSN 15384101

Mills, A. A. (February 2006) p63: oncogene or tumor suppressor? Curr Opin Genet Dev, 16 (1). pp. 38-44. ISSN 0959-437X (Print)

Yang, L. V., Wan, J., Ge, Y., Fu, Z., Kim, S. Y., Fujiwara, Y., Taub, J. W., Matherly, L. H., Eliason, J., Li, L. (2006) The GATA site-dependent hemogen promoter is transcriptionally regulated by GATA1 in hematopoietic and leukemia cells. Leukemia, 20 (3). pp. 417-425. ISSN 08876924

Laurikkala, J., Mikkola, M. L., James, M., Tummers, M., Mills, A. A., Thesleff, I. (2006) p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development, 133 (8). pp. 1553-1563. ISSN 09501991

Jacobs, W. B., Govoni, G., Ho, D., Atwal, J. K., Barnabe-Heider, F., Keyes, W. M., Mills, A. A., Miller, F. D., Kaplan, D. R. (December 2005) p63 is an essential proapoptotic protein during neural development. Neuron, 48 (5). pp. 743-756. ISSN 0896-6273

Mills, A. A. (September 2005) p53: link to the past, bridge to the future. Genes Dev, 19 (18). pp. 2091-9. ISSN 0890-9369 (Print)

Keyes, William M., Wu, Ying, Vogel, Hannes, Guo, Xuecui, Lowe, Scott W., Mills, Alea A. (September 2005) p63 deficiency activates a program of cellular senescence and leads to accelerated aging. Genes Dev, 19 (17). pp. 1986-99. ISSN 0890-9369 (Print)

Kurita, T., Cunha, G. R., Robboy, S. J., Mills, A. A., Medina, R. T. (September 2005) Differential expression of p63 isoforms in female reproductive organs. Mechanisms of Development, 122 (9). pp. 1043-1055. ISSN 0925-4773

Ihrie, R. A., Marques, M. R., Nguyen, B. T., Horner, J. S., Papazoglu, C., Bronson, R. T., Mills, A. A., Attardi, L. D. (March 2005) Perp is a p63-regulated gene essential for epithelial integrity. Cell, 120 (6). pp. 843-856. ISSN 0092-8674

Kurita, T., Medina, R. T., Mills, A. A., Cunha, G. R. (October 2004) Role of p63 and basal cells in the prostate. Development, 131 (20). pp. 4955-4964. ISSN 0950-1991

Kurita, T., Mills, A. A., Cunha, G. R. (April 2004) Roles of p63 in the diethylstilbestrol-induced cervicovaginal adenosis. Development, 131 (7). pp. 1639-1649. ISSN 0950-1991

Koster, M. I., Kim, S., Mills, A. A., DeMayo, F. J., Roop, D. R. (January 2004) p63 is the molecular switch for initiation of an epithelial stratification program. Genes & Development, 18 (2). pp. 126-131. ISSN 0890-9369

Nishijima, I., Mills, A., Qi, Y., Mills, M., Bradley, A. (July 2003) Two new balancer chromosomes on mouse chromosome 4 to facilitate functional annotation of human chromosome 1p. Genesis, 36 (3). pp. 142-148. ISSN 1526-954X

Keyes, W. M., Mills, A. A. (February 2003) Inducible systems see the light. Trends in Biotechnology, 21 (2). pp. 53-55. ISSN 0167-7799

Mills, A. (April 2002) Conducting the exploration of gene function. Seminars in Cell & Developmental Biology, 13 (2). p. 107. ISSN 1084-9521

Garcia, E. L., Mills, A. A. (April 2002) Getting around lethality with inducible Cre-mediated excision. Seminars in Cell & Developmental Biology, 13 (2). pp. 151-158. ISSN 1084-9521

Mills, A. A., Qi, Y., Bradley, A. (February 2002) Conditional inactivation of p63 by Cre-mediated excision. Genesis, 32 (2). pp. 138-141. ISSN 1526-954X

Su, H., Mills, A. A., Wang, X. Z., Bradley, A. (February 2002) A targeted X-linked CMV-Cre line. Genesis, 32 (2). pp. 187-188. ISSN 1526-954X

Mills, A. A. (June 2001) Changing colors in mice: an inducible system that delivers. Genes & Development, 15 (12). pp. 1461-1467. ISSN 0890-9369

Mills, A. A., Bradley, A. (June 2001) From mouse to man: generating megabase chromosome rearrangements. Trends in Genetics, 17 (6). pp. 331-339. ISSN 0168-9525

Zheng, B., Mills, A. A., Bradley, A. (2001) Introducing defined chromosomal rearrangements into the mouse genome. Methods, 24 (1). pp. 81-94. ISSN 10462023 (ISSN)

Mills, A. A., Mills, M. J., Gardiner, D. M., Bryant, S. V., Stanbridge, E. J. (1999) Analysis of the pattern of QM expression during mouse development. Differentiation, 64 (3). pp. 161-171. ISSN 03014681 (ISSN)

Mills, A. A., Zheng, B., Wang, X. J., Vogel, H., Roop, D. R., Bradley, A. (1999) p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature, 398 (6729). pp. 708-713. ISSN 00280836 (ISSN)

Zheng, B., Mills, A. A., Bradley, A. (1999) A system for rapid generation of coat color-tagged knockouts and defined chromosomal rearrangements in mice. Nucleic Acids Research, 27 (11). pp. 2354-2360. ISSN 03051048 (ISSN)

Nguyen, Y. H., Mills, A. A., Stanbridge, E. J. (1998) Assembly of the QM protein onto the 60S ribosomal subunit occurs in the cytoplasm. Journal of Cellular Biochemistry, 68 (2). pp. 281-285. ISSN 07302312 (ISSN)

Farmer, A. A., Loftus, T. M., Mills, A. A., Sato, K. Y., Neill, J. D., Tron, T., Yang, M., Trumpower, B. L., Stanbridge, E. J. (1994) Extreme evolutionary conservation of QM, a novel c-Jun associated transcription factor. Human Molecular Genetics, 3 (5). pp. 723-728. ISSN 09646906 (ISSN)

Stanbridge, E., Farmer, A., Mills, A., Loftus, T., Kongkasuriyachai, D., Dowdy, S., Weissman, B. (1994) Molecular characterization of QM, a novel gene with properties consistent with tumor suppressor function. Cold Spring Harbor Symposia on Quantitative Biology, 59. pp. 573-576. ISSN 00917451 (ISSN)

Harth, G., Andrews, N., Mills, A. A., Engel, J. C., Smith, R., McKerrow, J. H. (1993) Peptide-fluoromethyl ketones arrest intracellular replication and intercellular transmission of Trypanosoma cruzi. Molecular and Biochemical Parasitology, 58 (1). pp. 17-24. ISSN 01666851 (ISSN)

Eakin, A. E., Mills, A. A., Harth, G., McKerrow, J. H., Craik, C. S. (1992) The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi. Journal of Biological Chemistry, 267 (11). pp. 7411-7420. ISSN 00219258 (ISSN)

Conference or Workshop Item

Sun, Sherine Xueqin, Klingbeil, Olaf, Vakoc, Christopher, Mills, Alea (2023) BRD8-driven EP400 complex hijacks H2AZ to maintain proliferation in glioblastoma. In: American Association for Cancer Research Annual Meeting 2023, 2023 Apr 14-19, Orlando, FL.

Mills, Alea A, Hwang, Dong-Woo (October 2014) The tumor suppressor CHD5 is an epigenetic regulator of neuronal cell fate. In: AACR Annual Meeting.

Thesis

Johnson, David (July 2022) ELUCIDATING THE EFFECTS OF DEPLETING BRPF1 IN HUMAN GBM. PhD thesis, Cold Spring Harbor Laboratory.

Video

Mills, A. A. (November 2011) Talk from Alea Mills at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)