3D visualization of the regional differences

Ellegood, J., Anagnostou, E., Babineau, B. A., Crawley, J. N., Lin, L., Genestine, M., DiCicco-Bloom, E., Lai, J. K., Foster, J. A., Penagarikano, O., Geschwind, D. H., Pacey, L. K., Hampson, D. R., Laliberte, C. L., Mills, A. A., Tam, E., Osborne, L. R., Kouser, M., Espinosa-Becerra, F., Xuan, Z., Powell, C. M., Raznahan, A., Robins, D. M., Nakai, N., Nakatani, J., Takumi, T., van Eede, M. C., Kerr, T. M., Muller, C., Blakely, R. D., Veenstra-VanderWeele, J., Henkelman, R. M., Lerch, J. P. (February 2015) 3D visualization of the regional differences. Mol Psychiatry, 20 (1). p. 1. ISSN 1359-4184

URL: http://www.ncbi.nlm.nih.gov/pubmed/25648202
DOI: 10.1038/mp.2014.168


We examined 26 different mouse models related to autism and identified three groups that shared similar neuroanatomical phenotypes. These three groups and their regional differences are shown here. Anything highlighted in red was determined to be larger in that group (median effect size for group >0.5) and anything highlighted in blue was determined to be smaller in that group (median effect size for group < − 0.5). These differences are shown in 3D in an axial representation either looking from above (a) or below (b) the mouse brain. For more information on this topic, please refer to the article by Ellegood et al on pages 118–125.

Item Type: Paper
Uncontrolled Keywords: Animals Brain/*anatomy & histology Imaging, Three-Dimensional/*methods Mice *Neuroimaging
Subjects: diseases & disorders > mental disorders > personality disorders > autism
Investigative techniques and equipment > brain atlas
Investigative techniques and equipment > imaging
CSHL Authors:
Communities: CSHL labs > Mills lab
Depositing User: Matt Covey
Date: February 2015
Date Deposited: 02 Apr 2015 14:38
Last Modified: 02 Feb 2017 16:17
PMCID: PMC5131793
Related URLs:
URI: https://repository.cshl.edu/id/eprint/31308

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