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Ramesh, M., Krishnan, N., Muthuswamy, S. K., Tonks, N. K. (2015) A Novel Phosphatidic Acid-Protein Tyrosine Phosphatase D2 Axis is Essential for ERBB2 Signaling in Mammary Epithelial Cells. Journal of Biological Chemistry, 290 (15). pp. 9646-9659. ISSN 0021-9258

Krishnan, N., Koveal, D., Miller, D. H., Xue, B., Akshinthala, S. D., Kragelj, J., Jensen, M. R., Gauss, C. M., Page, R., Blackledge, M., Muthuswamy, S. K., Peti, W., Tonks, N. K. (2014) Targeting the disordered C terminus of PTP1B with an allosteric inhibitor. Nature Chemical Biology, 10 (7). pp. 558-566. ISSN 15524450

Feigin, M. E., Akshinthala, S. D., Araki, K., Rosenberg, A. Z., Muthuswamy, L. B., Martin, B., Lehmann, B. D., Berman, H. K., Pietenpol, J. A., Cardiff, R. D., Muthuswamy, S. K. (2014) Mislocalization of the cell polarity protein Scribble promotes mammary tumorigenesis and is associated with basal breast cancer. Cancer Research, 74 (11). pp. 3180-3194. ISSN 0008-5472

Feigin, M. E., Xue, B., Hammell, M. C., Muthuswamy, S. K. (2014) G-protein-coupled receptor GPR161 is overexpressed in breast cancer and is a promoter of cell proliferation and invasion. Proceedings of the National Academy of Sciences of the United States of America, 111 (11). pp. 4191-6. ISSN 0027-8424

Feigin, M. E. (2013) Harnessing the genome for characterization of G-protein coupled receptors in cancer pathogenesis. FEBS J, 280 (19). pp. 4729-38. ISSN 1742-4658 (Electronic)1742-464X (Linking)

Wang, H., Lacoche, S., Huang, L., Xue, B., Muthuswamy, S. K. (2013) Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly. Proceedings of the National Academy of Sciences of the United States of America, 110 (1). pp. 163-168. ISSN 00278424

Xue, B., Krishnamurthy, K., Allred, D. C., Muthuswamy, S. K. (2013) Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion. Nature Cell Biology, 15 (2). pp. 189-200. ISSN 1465-7392

Xue, B., Krishnamurthy, K., Allred, D. C., Muthuswamy, S. K. (2012) Loss of Par3 promotes breast cancer metastasis by compromising cell-cell cohesion. Nat Cell Biol. ISSN 1476-4679 (Electronic)1465-7392 (Linking)

Muthuswamy, S. K. (2012) Autocrine prolactin: an emerging market for homegrown (prolactin) despite the imports. Genes Dev, 26 (20). pp. 2253-8. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Yu, M., Lin, G., Arshadi, N., Kalatskaya, I., Xue, B., Haider, S., Nguyen, F., Boutros, P. C., Elson, A., Muthuswamy, L. B., Tonks, N. K., Muthuswamy, S. K. (2012) Expression profiling during mammary epithelial cell 3D morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2 mediated transformation. Mol Cell Biol, 32 (19). pp. 3913-3924. ISSN 1098-5549 (Electronic)0270-7306 (Linking)

Yang, Z., Xue, B., Umitsu, M., Ikura, M., Muthuswamy, S. K., Neel, B. G. (2012) The Signaling Adaptor Gab1 Regulates Cell Polarity by Acting as a PAR Protein Scaffold. Molecular Cell, 47 (3). pp. 469-483.

Muthuswamy, S. K., Xue, B. (2012) Cell Polarity as a Regulator of Cancer Cell Behavior Plasticity. Annu Rev Cell Dev Biol, 28 (28). pp. 599-625. ISSN 1530-8995 (Electronic)1081-0706 (Linking)

Chatterjee, S., Seifried, L., Feigin, M. E., Gibbons, D. L., Scuoppo, C., Lin, W., Rizvi, Z. H., Lind, E., Dissanayake, D., Kurie, J., Ohashi, P., Muthuswamy, S. K. (2012) Dysregulation of Cell Polarity Proteins Synergize with Oncogenes or the Microenvironment to Induce Invasive Behavior in Epithelial Cells. PLoS ONE, 7 (4). ISSN 1932-6203

Anczukow, O., Rosenberg, A. Z., Akerman, M., Das, S., Zhan, L., Karni, R., Muthuswamy, S. K., Krainer, A. R. (2012) The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation. Nature Structural Molecular Biology, 19 (2). pp. 220-228. ISSN 1545-9985 (Electronic)1545-9985 (Linking)

Lin, G., Aranda, V., Muthuswamy, S. K., Tonks, N. K. (2011) Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'. Genes & Development, 25 (13). pp. 1412-1425. ISSN 0890-9369

Simpson, D. R., Yu, M., Zheng, S. Y., Zhao, Z. M., Muthuswamy, S. K., Tansey, W. P. (2011) Epithelial Cell Organization Suppresses Myc Function by Attenuating Myc Expression. Cancer Research, 71 (11). pp. 3822-3830. ISSN 0008-5472

Wang, G. H., Krishnamurthy, K., Tangpisuthipongsa, D. (2011) Protection of murine neural progenitor cells by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin in the low nanomolar concentration range. Journal of Neurochemistry, 117 (4). pp. 703-711. ISSN 0022-3042

Muthuswamy, S. K. (2011) Trastuzumab resistance: all roads lead to SRC. Nature Medicine, 17 (4). pp. 416-8. ISSN 1078-8956

Keyes, W. M. , Pecoraro, M., Aranda, V., Vernersson-Lindahl, E., Li, W., Vogel, H., Guo, X., Garcia, E. L., Michurina, T. V., Enikolopov, G. N., Muthuswamy, S. K., Mills, A. A. (2011) DeltaNp63alpha Is an Oncogene that Targets Chromatin Remodeler Lsh to Drive Skin Stem Cell Proliferation and Tumorigenesis. Cell Stem Cell, 8 (2). pp. 164-76. ISSN 1875-9777 (Electronic)

Muthuswamy, S. K. (2011) 3D culture reveals a signaling network. Breast Cancer Research, 13 (1). ISSN 1465-542X

Arias-Romero, L. E., Villamar-Cruz, O., Pacheco, A., Kosoff, R., Huang, M., Muthuswamy, S. K., Chernoff, J. (2010) A Rac-Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells. Oncogene, 29 (43). pp. 5839-49. ISSN 0950-9232

Cabodi, S., Tinnirello, A., Bisaro, B., Tornillo, G., Camacho-Leal, M. D., Forni, G., Cojoca, R., Iezzi, M., Amici, A., Montani, M., Eva, A., Di Stefano, P., Muthuswamy, S. K., Tarone, G., Turco, E., Defilippi, P. (2010) p130Cas is an essential transducer element in ErbB2 transformation. Faseb J. ISSN 1530-6860 (Electronic) 0892-6638 (Linking)

Huang, L., Muthuswamy, S. K. (2010) Polarity protein alterations in carcinoma: a focus on emerging roles for polarity regulators. Current Opinion in Genetics and Development, 20 (1). pp. 41-50.

Lucs, A. V., Muller, W. J., Muthuswamy, S. K. (2010) Shc is required for ErbB2-induced inhibition of apoptosis but is dispensable for cell proliferation and disruption of cell polarity. Oncogene, 29 (2). pp. 174-187. ISSN 0950-9232

Ling, C., Zuo, D., Xue, B., Muthuswamy, S. K., Muller, W. J. (2010) A novel role for 14-3-3σ in regulating epithelial cell polarity. Genes and Development, 24 (9). pp. 947-956.

Feigin, M. E., Muthuswamy, S. K. (2009) Polarity proteins regulate mammalian cell-cell junctions and cancer pathogenesis. Curr Opin Cell Biol, 21 (5). 694-700 .

Muthuswamy, S. K. (2009) A New Tumor Suppressor That Regulates Tissue Architecture. PLoS Medicine, 6 (5). e1000073.

Zavadil, J., Haley, J., Kalluri, R., Muthuswamy, S. K., Thompson, E. (2008) Epithelial-Mesenchymal Transition. Cancer Res, 68 (23). pp. 9574-9577.

Zhan, L., Rosenberg, A. , Bergami, K. C., Yu, M., Xuan, Z. Y., Jaffe, A. B., Allred, C., Muthuswamy, S. K. (2008) Deregulation of Scribble Promotes Mammary Tumorigenesis and Reveals a Role for Cell Polarity in Carcinoma. Cell, 135 (5). pp. 865-878.

Aranda, V., Nolan, M. E., Muthuswamy, S. K. (2008) Par complex in cancer: a regulator of normal cell polarity joins the dark side. Oncogene, 27 (55). pp. 6878-87.

Nolan, M. E., Aranda, V., Lee, S., Lakshmi, B., Basu, S., Allred, D. C., Muthuswamy, S. K. (2008) The polarity protein Par6 induces cell proliferation and is overexpressed in breast cancer. Cancer Res, 68 (20). pp. 8201-9.

Xiang, B., Chatti, K., Qiu, H., Lakshmi, B., Krasnitz, A., Hicks, J. B., Yu, M., Miller, W. T., Muthuswamy, S. K. (2008) Brk is coamplified with ErbB2 to promote proliferation in breast cancer. Proc Natl Acad Sci U S A, 105 (34). pp. 12463-8.

Guix, M., de Matos Granja, N., Meszoely, I., Adkins, T. B., Wieman, B. M., Frierson, K. E., Sanchez, V., Sanders, M. E., Grau, A. M., Mayer, I. A., Pestano, G., Shyr, Y., Muthuswamy, S., Calvo, B., Krontiras, H., Krop, I. E., Kelley, M. C., Arteaga, C. L. (2008) Short Preoperative Treatment With Erlotinib Inhibits Tumor Cell Proliferation in Hormone Receptor Positive Breast Cancers. J Clin Oncol, 26 (6). pp. 897-906.

Feigin, M. E., Muthuswamy, S. K. (2008) ErbB receptors and cell polarity: New pathways and paradigms for understanding cell migration and invasion. Experimental Cell Research, 315 (4). pp. 707-716. ISSN 0014-4827

Ibarra, I., Erlich, Y., Muthuswamy, S. K., Sachidanandam, R., Hannon, Gregory J. (2007) A role for microRNAs in maintenance of mouse mammary epithelial progenitor cells. Genes Dev, 21 (24). pp. 3238-43. ISSN 0890-9369 (Print)

Tonks, N. K., Muthuswamy, S. K. (2007) A Brake Becomes an Accelerator: PTP1B-A New Therapeutic Target for Breast Cancer. Cancer Cell, 11 (3). pp. 214-6. ISSN 1535-6108 (Print)

Aranda, V., Haire, T., Nolan, M. E., Calarco, J. P., Rosenberg, A. Z., Fawcett, J. P., Pawson, T., Muthuswamy, S. K. (2006) Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control. Nat Cell Biol, 8 (11). pp. 1235-45. ISSN 1465-7392 (Print)

Muthuswamy, S. K. (2006) ErbB2 makes beta 4 integrin an accomplice in tumorigenesis. Cell, 126 (3). pp. 443-5. ISSN 0092-8674 (Print)

Zhan, L., Xiang, B., Muthuswamy, S. K. (2006) Controlled activation of ErbB1/ErbB2 heterodimers promote invasion of three-dimensional organized epithelia in an ErbB1-dependent manner: implications for progression of ErbB2-overexpressing tumors. Cancer Res, 66 (10). pp. 5201-8. ISSN 0008-5472 (Print)

Wang, S. E., Narasanna, A., Perez-Torres, M., Xiang, B., Wu, F. Y., Yang, S., Carpenter, G., Gazdar, A. F., Muthuswamy, S. K., Arteaga, C. L. (2006) HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell, 10 (1). pp. 25-38. ISSN 15356108

Reginato, M. J., Muthuswamy, S. K. (2006) Illuminating the center: Mechanisms regulating lumen formation and maintenance in mammary morphogenesis. Journal of Mammary Gland Biology and Neoplasia, 11 (3-4). pp. 205-211. ISSN 10833021

Xiang, B., Muthuswamy, S. K. (2006) Using three-dimensional acinar structures for molecular and cell biological assays. Methods Enzymol, 406. pp. 692-701. ISSN 0076-6879 (Print)

Muthuswamy, S. K. (2005) Regulation of epithelial cell polarity during carcinogenesis. Breast Cancer Research, 7. S7-S7. ISSN 1465-5411

Debnath, J., Muthuswamy, S. K., Brugge, J. S. (2003) Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods, 30 (3). pp. 256-268. ISSN 1046-2023

Miranti, C. K., Bill, H. M., Modres, S. L., Rao, V. R., Knudsen, B., Muthuswamy, S. K., Brugge, J. S. (2003) Integrin-induced EGFR activation and control of the cell cycle in epithelial cells. Faseb Journal, 17 (5). A974-A974. ISSN 0892-6638

Reginato, M. J., Mills, K., Debnath, J., Paulus, J., Muthuswamy, S., Brugge, J. (2002) Bim regulation or lumen formation in epithelial acini is blocked by oncogenes. Molecular Biology of the Cell, 13. 4A-4A. ISSN 1059-1524

Muthuswamy, S. K., Li, D. M., Lelievre, S., Bissell, M. J., Brugge, J. S. (2001) ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini. Nature Cell Biology, 3 (9). pp. 785-792. ISSN 1465-7392

This list was generated on Tue Sep 26 04:05:40 2017 EDT.
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