Items where Subject is "chemotherapy"

Paper

Abera, M., Sordella, R., Kazanietz, M. (April 2013) PKC alpha is implicated in epithelial to mesenchymal transition and erlotinib resistance in non-small cell lung carcinoma cells. Cancer Research, 73 (8 (Sup). p. 5261. ISSN 0008-5472

Anderson, S. E., Keohan, M. L., D'Adamo, D. R., Maki, R. G. (2006) A retrospective analysis of vinorelbine chemotherapy for patients with previously treated soft-tissue sarcomas. Sarcoma, 2006. p. 15947. ISSN 1357-714X (Print)1357-714X (Linking)

Bharathy, N., Berlow, N. E., Wang, E., Abraham, J., Settelmeyer, T. P., Hooper, J. E., Svalina, M. N., Ishikawa, Y., Zientek, K., Bajwa, Z., Goros, M. W., Hernandez, B. S., Wolff, J. E., Rudek, M. A., Xu, L., Anders, N. M., Pal, R., Harrold, A. P., Davies, A. M., Ashok, A., Bushby, D., Mancini, M., Noakes, C., Goodwin, N. C., Ordentlich, P., Keck, J., Hawkins, D. S., Rudzinski, E. R., Chatterjee, B., Bachinger, H. P., Barr, F. G., Liddle, J., Garcia, B. A., Mansoor, A., Perkins, T. J., Vakoc, C. R., Michalek, J. E., Keller, C. (November 2018) The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma. Sci Signal, 11 (557). ISSN 1945-0877

Bhattacharjee, S., Nandi, S. (December 2016) Choices have consequences: the nexus between DNA repair pathways and genomic instability in cancer. Clin Transl Med, 5 (1). p. 45. ISSN 2001-1326

Blay, J. Y., Schoffski, P., Bauer, S., Krarup-Hansen, A., Benson, C., D'Adamo, D. R., Jia, Y., Maki, R. G. (May 2019) Eribulin versus dacarbazine in patients with leiomyosarcoma: subgroup analysis from a phase 3, open-label, randomised study. Br J Cancer, 120 (11). pp. 1026-1032. ISSN 0007-0920

Borniger, J. C., Gaudier-Diaz, M. M., Zhang, N., Nelson, R. J., DeVries, A. C. (July 2015) Cytotoxic chemotherapy increases sleep and sleep fragmentation in non-tumor-bearing mice. Brain Behav Immun, 47. pp. 218-27. ISSN 1090-2139 (Electronic)0889-1591 (Linking)

Borniger, J. C., Walker Ii, W. H., Gaudier-Diaz, M. M., Stegman, C. J., Zhang, N., Hollyfield, J. L., Nelson, R. J., DeVries, A. C. (January 2017) Time-of-Day Dictates Transcriptional Inflammatory Responses to Cytotoxic Chemotherapy. Sci Rep, 7. p. 41220. ISSN 2045-2322 (Electronic)2045-2322 (Linking)

Caiado, F., Maia-Silva, D., Jardim, C., Schmolka, N., Carvalho, T., Reforco, C., Faria, R., Kolundzija, B., Simoes, A. E., Baubec, T., Vakoc, C. R., da Silva, M. G., Manz, M. G., Schumacher, T. N., Norell, H., Silva-Santos, B. (November 2019) Lineage tracing of acute myeloid leukemia reveals the impact of hypomethylating agents on chemoresistance selection. Nat Commun, 10 (1). p. 4986. ISSN 2041-1723

Canter, R. J., Qin, L. X., Downey, R. J., Brennan, M. F., Singer, S., Maki, R. G. (November 2007) Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft-tissue sarcoma of the extremity : a retrospective analysis. Cancer, 110 (9). pp. 2050-60. ISSN 0008-543X (Print)0008-543X (Linking)

Canter, R. J., Qin, L. X., Maki, R. G., Brennan, M. F., Ladanyi, M., Singer, S. (December 2008) A synovial sarcoma-specific preoperative nomogram supports a survival benefit to ifosfamide-based chemotherapy and improves risk stratification for patients. Clin Cancer Res, 14 (24). pp. 8191-7. ISSN 1078-0432 (Print)1078-0432 (Linking)

Clark, J. W., Camidge, D. R., Kwak, E. L., Maki, R. G., Shapiro, G. I., Chen, I., Tan, W., Randolph, S., Christensen, J. G., Ozeck, M., Tang, Y., Wilner, K. D., Salgia, R. (January 2020) Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer. Future Oncol, 16 (1). pp. 4289-4301. ISSN 1479-6694

Connell, Claire M, Brais, Rebecca, Whitaker, Hayley, Upponi, Sara, Beh, Ian, Risdall, Jane, Corrie, Pippa, Janowitz, Tobias, Jodrell, Duncan I (January 2020) Early relapse on adjuvant gemcitabine associated with an exceptional response to 2nd line capecitabine chemotherapy in a patient with pancreatic adenosquamous carcinoma with strong intra-tumoural expression of cytidine deaminase: a case report. BMC Cancer, 20 (1). p. 38. ISSN 1471-2407

Cook, N., Basu, B., Smith, D. M., Gopinathan, A., Evans, J., Steward, W. P., Palmer, D., Propper, D., Venugopal, B., Hategan, M., Anthoney, D. A., Hampson, L. V., Nebozhyn, M., Tuveson, D., Farmer-Hall, H., Turner, H., McLeod, R., Halford, S., Jodrell, D. (March 2018) A phase I trial of the gamma-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma. Br J Cancer, 118 (6). pp. 793-801. ISSN 0007-0920

Cormier, J. N., Huang, X., Xing, Y., Thall, P. F., Wang, X., Benjamin, R. S., Pollock, R. E., Antonescu, C. R., Maki, R. G., Brennan, M. F., Pisters, P. W. (November 2004) Cohort analysis of patients with localized, high-risk, extremity soft tissue sarcoma treated at two cancer centers: chemotherapy-associated outcomes. J Clin Oncol, 22 (22). pp. 4567-74. ISSN 0732-183X (Print)0732-183X (Linking)

Corrie, P., Qian, W., Gopinathan, A., Williams, M., Brais, R., Valle, J. W., Basu, B., Falk, S., Iwuji, C., Wasan, H., Palmer, D., Scott-Brown, M., Wadsley, J., Arif, S., Bax, L., Bundi, P., Skells, R., Neesse, A., Tuveson, D., Jodrell, D. (September 2017) Strong tumour cytidine deaminase (CDA) staining predicts for improved survival associated with sequential nab-Paclitaxel (nabP) and gemcitabine (GEM) chemotherapy as first line treatment of patients (pts) with metastatic pancreatic adenocarcinoma (mPDAC). Annals of Oncology, 28 (Supple). 73P. ISSN 0923-7534

Corrie, P.G., Qian, W., Basu, B., Valle, J.W., Falk, S., Lwuji, C., Wasan, H., Palmer, D., Scott-Brown, M., Wadsley, J., Arif, S., Bridgewater, J., Propper, D., Gillmore, R., Gopinathan, A., Skells, R., Bundi, P., Brais, R., Dalchau, K., Bax, L., Chhabra, A., Machin, A., Dayim, A., McAdam, K., Cummins, S., Wall, L., Ellis, R., Anthoney, A., Evans, J., Ma, Y.T., Isherwood, C., Neesse, A., Tuveson, D., Jodrell, D. I. (April 2020) Scheduling Nab-Paclitaxel Combined With Gemcitabine as First-Line Treatment for Metastatic Pancreatic Adenocarcinoma. Br J Cancer. ISSN 0007-0920

Davis, L. E., Bolejack, V., Ryan, C. W., Ganjoo, K. N., Loggers, E. T., Chawla, S., Agulnik, M., Livingston, M. B., Reed, D., Keedy, V., Rushing, D., Okuno, S., Reinke, D. K., Riedel, R. F., Attia, S., Mascarenhas, L., Maki, R. G. (June 2019) Randomized Double-Blind Phase II Study of Regorafenib in Patients With Metastatic Osteosarcoma. J Clin Oncol, 37 (16). pp. 1424-1431. ISSN 0732-183x

Dent, P., Booth, L., Roberts, J. L., Liu, J., Poklepovic, A., Lalani, A. S., Tuveson, D., Martinez, J., Hancock, J. F. (June 2019) Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells. Oncogene. ISSN 0950-9232

Driehuis, E., Kolders, S., Spelier, S., Lohmussaar, K., Willems, S. M., Devriese, L. A., de Bree, R., de Ruiter, E. J., Korving, J., Begthel, H., Van Es, J. H., Geurts, V., He, G. W., van Jaarsveld, R. H., Oka, R., Muraro, M. J., Vivie, J., Zandvliet, Mmjm, Hendrickx, A. P. A., Iakobachvili, N., Sridevi, P., Kranenburg, O., van Boxtel, R., Kops, Gjpl, Tuveson, D. A., Peters, P. J., van Oudenaarden, A., Clevers, H. (May 2019) Oral mucosal organoids as a potential platform for personalized cancer therapy. Cancer Discov, 9 (7). pp. 852-871. ISSN 2159-8274

Drilon, A. D., Popat, S., Bhuchar, G., D'Adamo, D. R., Keohan, M. L., Fisher, C., Antonescu, C. R., Singer, S., Brennan, M. F., Judson, I., Maki, R. G. (December 2008) Extraskeletal myxoid chondrosarcoma: a retrospective review from 2 referral centers emphasizing long-term outcomes with surgery and chemotherapy. Cancer, 113 (12). pp. 3364-71. ISSN 0008-543X (Print)0008-543X (Linking)

Early Breast Cancer Trialists' Collaborative Group (EBCTCG) (February 2022) Aromatase inhibitors versus tamoxifen in premenopausal women with oestrogen receptor-positive early-stage breast cancer treated with ovarian suppression: a patient-level meta-analysis of 7030 women from four randomised trials. The Lancet Oncology. ISSN 1470-2045

Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Ele, Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) (April 2023) Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials. The Lancet, 401 (10384). pp. 1277-1292. ISSN 0140-6736

Eilber, F. C., Brennan, M. F., Eilber, F. R., Eckardt, J. J., Grobmyer, S. R., Riedel, E., Forscher, C., Maki, R. G., Singer, S. (July 2007) Chemotherapy is associated with improved survival in adult patients with primary extremity synovial sarcoma. Ann Surg, 246 (1). pp. 105-13. ISSN 0003-4932 (Print)0003-4932 (Linking)

Eilber, F. C., Eilber, F. R., Eckardt, J., Rosen, G., Riedel, E., Maki, R. G., Brennan, M. F., Singer, S. (October 2004) The impact of chemotherapy on the survival of patients with high-grade primary extremity liposarcoma. Ann Surg, 240 (4). 686-95; discussion 695. ISSN 0003-4932 (Print)0003-4932 (Linking)

Ferraro, Emanuela, Singh, Jasmeet, Patil, Sujata, Razavi, Pedram, Modi, Shanu, Chandarlapaty, Sarat, Barrio, Andrea V, Malani, Rachna, Mellinghoff, Ingo K, Boire, Adrienne, Wen, Hannah Y, Brogi, Edi, Seidman, Andrew D, Norton, Larry, Robson, Mark E, Dang, Chau T (March 2022) Incidence of brain metastases in patients with early HER2-positive breast cancer receiving neoadjuvant chemotherapy with trastuzumab and pertuzumab. npj Breast Cancer, 8 (1). p. 37. ISSN 2374-4677

Ford, H. E., Marshall, A., Bridgewater, J. A., Janowitz, T., Coxon, F. Y., Wadsley, J., Mansoor, W., Fyfe, D., Madhusudan, S., Middleton, G. W., Swinson, D., Falk, S., Chau, I., Cunningham, D., Kareclas, P., Cook, N., Blazeby, J. M., Dunn, J. A. (January 2014) Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR-02): an open-label, phase 3 randomised controlled trial. Lancet Oncol, 15 (1). pp. 78-86. ISSN 1470-2045

Frezza, A. M., Assi, T., Lo Vullo, S., Ben-Ami, E., Dufresne, A., Yonemori, K., Noguchi, E., Siontis, B., Ferraro, R., Teterycz, P., Duffaud, F., Ravi, V., Vincenzi, B., Gelderblom, H., Pantaleo, M. A., Baldi, G. G., Desar, I., Fedenko, A., Maki, R. G., Jones, R. L., Benjamin, R. S., Blay, J. Y., Kawai, A., Gounder, M., Gronchi, A., Le Cesne, A., Mir, O., Czarnecka, A. M., Schuetze, S., Wagner, A. J., Adam, J., Barisella, M., Sbaraglia, M., Hornick, J. L., Meurgey, A., Mariani, L., Casali, P. G., Thornton, K., Stacchiotti, S. (September 2019) Systemic treatments in MDM2 positive intimal sarcoma: A multicentre experience with anthracycline, gemcitabine, and pazopanib within the World Sarcoma Network. Cancer. ISSN 0008-543x

Fury, M. G., Antonescu, C. R., Van Zee, K. J., Brennan, M. F., Maki, R. G. (May 2005) A 14-year retrospective review of angiosarcoma: clinical characteristics, prognostic factors, and treatment outcomes with surgery and chemotherapy. Cancer J, 11 (3). pp. 241-7. ISSN 1528-9117 (Print)1528-9117 (Linking)

Garcia-Carbonero, R., Supko, J. G., Maki, R. G., Manola, J., Ryan, D. P., Harmon, D., Puchalski, T. A., Goss, G., Seiden, M. V., Waxman, A., Quigley, M. T., Lopez, T., Sancho, M. A., Jimeno, J., Guzman, C., Demetri, G. D. (August 2005) Ecteinascidin-743 (ET-743) for chemotherapy-naive patients with advanced soft tissue sarcomas: multicenter phase II and pharmacokinetic study. J Clin Oncol, 23 (24). pp. 5484-92. ISSN 0732-183X (Print)0732-183X (Linking)

Garcia-Carbonero, R., Supko, J. G., Manola, J., Seiden, M. V., Harmon, D., Ryan, D. P., Quigley, M. T., Merriam, P., Canniff, J., Goss, G., Matulonis, U., Maki, R. G., Lopez, T., Puchalski, T. A., Sancho, M. A., Gomez, J., Guzman, C., Jimeno, J., Demetri, G. D. (April 2004) Phase II and pharmacokinetic study of ecteinascidin 743 in patients with progressive sarcomas of soft tissues refractory to chemotherapy. J Clin Oncol, 22 (8). pp. 1480-90. ISSN 0732-183X (Print)0732-183X (Linking)

Gholami, Sepideh, Colby, Sarah, Horowitz, David P, Guthrie, Katherine A, Ben-Josef, Edgar, El-Khoueiry, Anthony B, Blanke, Charles D, Philip, Philip A, Kachnic, Lisa A, Ahmad, Syed A, Rocha, Flavio G (March 2023) Adjuvant Chemoradiation in Patients with Lymph Node-Positive Biliary Tract Cancers: Secondary Analysis of a Single-Arm Clinical Trial (SWOG 0809). Annals of Surgical Oncology, 30 (3). pp. 1354-1363. ISSN 1068-9265

Gholami, Sepideh, Kemeny, Nancy E, Boucher, Taryn M, Gönen, Mithat, Cercek, Andrea, Kingham, T Peter, Balachandran, Vinod, Allen, Peter, DeMatteo, Ronald, Drebin, Jeffrey, Jarnagin, William, D'Angelica, Michael (August 2020) Adjuvant Hepatic Artery Infusion Chemotherapy is Associated With Improved Survival Regardless of KRAS Mutation Status in Patients With Resected Colorectal Liver Metastases: A Retrospective Analysis of 674 Patients. Annals of Surgery, 272 (2). pp. 352-356. ISSN 0003-4932

Gholami, Sepideh, Stewart, Susan, Kemeny, Nancy, Gönen, Mithat, Groot Koerkamp, Bas, Cercek, Andrea, Kingham, Peter, Balachandran, Vinod, Allen, Peter, DeMatteo, Ronald, Wei, Alice, Connell, Louise, Drebin, Jeffrey, Jarnagin, William, D'Angelica, Michael (July 2021) Impact of Primary Tumor Laterality on Adjuvant Hepatic Artery Infusion Pump Chemotherapy in Resected Colon Cancer Liver Metastases: Analysis of 487 Patients. Annals of Surgical Oncology, 28 (7). pp. 3685-3694. ISSN 1068-9265

Ghosh, D., Nandi, S., Bhattacharjee, S. (October 2018) Combination therapy to checkmate Glioblastoma: clinical challenges and advances. Clin Transl Med, 7 (1). p. 33. ISSN 2001-1326 (Print)

Gounder, M. M., Mahoney, M. R., Van Tine, B. A., Ravi, V., Attia, S., Deshpande, H. A., Gupta, A. A., Milhem, M. M., Conry, R. M., Movva, S., Pishvaian, M. J., Riedel, R. F., Sabagh, T., Tap, W. D., Horvat, N., Basch, E., Schwartz, L. H., Maki, R. G., Agaram, N. P., Lefkowitz, R. A., Mazaheri, Y., Yamashita, R., Wright, J. J., Dueck, A. C., Schwartz, G. K. (December 2018) Sorafenib for Advanced and Refractory Desmoid Tumors. N Engl J Med, 379 (25). pp. 2417-2428. ISSN 0028-4793

Grabenstetter, Anne, Brogi, Edi, Thompson, Donna M, Blinder, Victoria S, Norton, Larry, Morrow, Monica, Robson, Mark E, Wen, Hannah Y (September 2023) Impact of reactive changes on multigene testing: histopathologic analysis of low-grade breast cancers with high-risk 21-gene recurrence scores. Breast Cancer Research and Treatment. ISSN 0167-6806

Grobmyer, S. R., Maki, R. G., Demetri, G. D., Mazumdar, M., Riedel, E., Brennan, M. F., Singer, S. (November 2004) Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma. Ann Oncol, 15 (11). pp. 1667-72. ISSN 0923-7534 (Print)0923-7534 (Linking)

Guix, M., de Matos Granja, N., Meszoely, I., Adkins, T. B., Wieman, B. M., Frierson, K. E., Sanchez, V., Sanders, M. E., Grau, A. M., Mayer, I. A., Pestano, G., Shyr, Y., Muthuswamy, S., Calvo, B., Krontiras, H., Krop, I. E., Kelley, M. C., Arteaga, C. L. (February 2008) Short Preoperative Treatment With Erlotinib Inhibits Tumor Cell Proliferation in Hormone Receptor Positive Breast Cancers. J Clin Oncol, 26 (6). pp. 897-906.

Hensley, M. L., Wathen, J. K., Maki, R. G., Araujo, D. M., Sutton, G., Priebat, D. A., George, S., Soslow, R. A., Baker, L. H. (April 2013) Adjuvant therapy for high-grade, uterus-limited leiomyosarcoma: results of a phase 2 trial (SARC 005). Cancer, 119 (8). pp. 1555-61. ISSN 1097-0142 (Electronic)0008-543X (Linking)

Hu, Tuo, Shukla, Surendra K, Vernucci, Enza, He, Chunbo, Wang, Dezhen, King, Ryan J, Jha, Kanupriya, Siddhanta, Kasturi, Mullen, Nicholas J, Attri, Kuldeep S, Murthy, Divya, Chaika, Nina V, Thakur, Ravi, Mulder, Scott E, Pacheco, Camila G, Fu, Xiao, High, Robin R, Yu, Fang, Lazenby, Audrey, Steegborn, Clemens, Lan, Ping, Mehla, Kamiya, Rotili, Dante, Chaudhary, Sarika, Valente, Sergio, Tafani, Marco, Mai, Antonello, Auwerx, Johan, Verdin, Eric, Tuveson, David, Singh, Pankaj K (July 2021) Metabolic Rewiring by Loss of Sirt5 Promotes Kras-induced Pancreatic Cancer Progression. Gastroenterology. ISSN 0016-5085

Huang, T. H., Wu, A. T. H., Cheng, T. S., Lin, K. T., Lai, C. J., Hsieh, H. W., Chang, P. M. H., Wu, C. W., Huang, C. Y. F., Chen, K. Y. (December 2019) In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non–small-cell lung cancer. Journal of Cellular and Molecular Medicine, 23 (12). pp. 8184-8195. ISSN 15821838 (ISSN)

Italiano, A., Garbay, D., Cioffi, A., Maki, R. G., Bui, B. (August 2012) Advanced pleomorphic liposarcomas: clinical outcome and impact of chemotherapy. Ann Oncol, 23 (8). pp. 2205-6. ISSN 1569-8041 (Electronic)0923-7534 (Linking)

Italiano, A., Mir, O., Cioffi, A., Palmerini, E., Piperno-Neumann, S., Perrin, C., Chaigneau, L., Penel, N., Duffaud, F., Kurtz, J. E., Collard, O., Bertucci, F., Bompas, E., Le Cesne, A., Maki, R. G., Ray Coquard, I., Blay, J. Y. (November 2013) Advanced chondrosarcomas: role of chemotherapy and survival. Ann Oncol, 24 (11). pp. 2916-22. ISSN 1569-8041 (Electronic)0923-7534 (Linking)

Italiano, A., Toulmonde, M., Cioffi, A., Penel, N., Isambert, N., Bompas, E., Duffaud, F., Patrikidou, A., Lortal, B., Le Cesne, A., Blay, J. Y., Maki, R. G., Schwartz, G. K., Antonescu, C. R., Singer, S., Coindre, J. M., Bui, B. (June 2012) Advanced well-differentiated/dedifferentiated liposarcomas: role of chemotherapy and survival. Ann Oncol, 23 (6). pp. 1601-7. ISSN 1569-8041 (Electronic)0923-7534 (Linking)

Izumchenko, E., Paz, K., Ciznadija, D., Sloma, I., Katz, A., Vasquez-Dunddel, D., Ben-Zvi, I., Stebbing, J., McGuire, W., Harris, W., Maki, R., Gaya, A., Bedi, A., Zacharoulis, S., Ravi, R., Wexler, L. H., Hoque, M. O., Rodriguez-Galindo, C., Pass, H., Peled, N., Davies, A., Morris, R., Hidalgo, M., Sidransky, D. (October 2017) Patient-derived xenografts effectively capture responses to oncology therapy in a heterogeneous cohort of patients with solid tumors. Ann Oncol, 28 (10). pp. 2595-2605. ISSN 0923-7534

Janowitz, T., Thuss-Patience, P., Marshall, A., Kang, J. H., Connell, C., Cook, N., Dunn, J., Park, S. H., Ford, H. (February 2016) Chemotherapy vs supportive care alone for relapsed gastric, gastroesophageal junction, and oesophageal adenocarcinoma: a meta-analysis of patient-level data. Br J Cancer, 114 (4). pp. 381-7. ISSN 0007-0920

Janowitz, T., Welsh, S., Warren, A. Y., Robson, J., Thomas, B., Shaw, A., Ainsworth, N. L., Neal, D. E., Mazhar, D. (October 2015) Prostatic relapse of an undifferentiated teratoma 24 years after orchidectomy. BMC Res Notes, 8. p. 524. ISSN 1756-0500

Janowitz, Tobias, Kleeman, Sam, Vonderheide, Robert H (April 2021) Reconsidering Dexamethasone for Antiemesis when Combining Chemotherapy and Immunotherapy. The Oncologist, 26 (4). pp. 269-273. ISSN 1083-7159

Johnstone, R. W., Ruefli, A. A., Lowe, S. W. (January 2002) Apoptosis: A link between cancer genetics and chemotherapy. Cell, 108 (2). pp. 153-164. ISSN 0092-8674

Jones, R. L., Chawla, S. P., Attia, S., Schoffski, P., Gelderblom, H., Chmielowski, B., Le Cesne, A., Van Tine, B. A., Trent, J. C., Patel, S., Wagner, A. J., Chugh, R., Heyburn, J. W., Weil, S. C., Wang, W., Viele, K., Maki, R. G. (April 2019) A phase 1 and randomized controlled phase 2 trial of the safety and efficacy of the combination of gemcitabine and docetaxel with ontuxizumab (MORAb-004) in metastatic soft-tissue sarcomas. Cancer, 125 (14). pp. 2445-2454. ISSN 0008-543x

Jones, R. L., Constantinidou, A., Thway, K., Ashley, S., Scurr, M., Al-Muderis, O., Fisher, C., Antonescu, C. R., D'Adamo, D. R., Keohan, M. L., Maki, R. G., Judson, I. R. (September 2011) Chemotherapy in clear cell sarcoma. Med Oncol, 28 (3). pp. 859-63. ISSN 1559-131X (Electronic)1357-0560 (Linking)

Jones, R. L., Demetri, G. D., Schuetze, S. M., Milhem, M., Elias, A., Van Tine, B. A., Hamm, J., McCarthy, S., Wang, G., Parekh, T., Knoblauch, R., Hensley, M. L., Maki, R. G., Patel, S., von Mehren, M. (August 2018) Efficacy and tolerability of trabectedin in elderly patients with sarcoma: subgroup analysis from a phase 3, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma. Ann Oncol, 29 (9). pp. 1995-2002. ISSN 0923-7534

Judge, Sean J, Cho, May, Gholami, Sepideh (November 2022) Genomic Predictors of Recurrence Patterns After Complete Resection of Colorectal Liver Metastases and Adjuvant Hepatic Artery Infusion Chemotherapy by Narayan et al. Annals of Surgical Oncology, 29 (12). pp. 7246-7247. ISSN 1068-9265

Kemper, E. M., Leenders, W., Kusters, B., Lyons, S., Buckle, T., Heerschap, A., Boogerd, W., Beijnen, J. H., van Tellingen, O. (December 2006) Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies. Eur J Cancer, 42 (18). pp. 3294-303. ISSN 0959-8049 (Print)0959-8049 (Linking)

Kim, S. Y., Cordeiro, M. H., Serna, V. A., Ebbert, K., Butler, L. M., Sinha, S., Mills, A. A., Woodruff, T. K., Kurita, T. (August 2013) Rescue of platinum-damaged oocytes from programmed cell death through inactivation of the p53 family signaling network. Cell Death and Differentiation, 20 (8). pp. 987-997.

Lin, A., Giuliano, C. J., Palladino, A., John, K. M., Abramowicz, C., Yuan, M. L., Sausville, E. L., Lukow, D. A., Liu, L., Chait, A. R., Galluzzo, Z. C., Tucker, C., Sheltzer, J. M. (September 2019) Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials. Sci Transl Med, 11 (509). ISSN 1946-6234

Lowe, S. W., Schmitt, C., Fridman, J., Rosenthal, C. (November 2001) Genetics of drug sensitivity and resistance in a mouse lymphoma model. Clinical Cancer Research, 7 (11). 3828S-3829S. ISSN 1078-0432

MacDiarmid, J. A., Langova, V., Bailey, D., Pattison, S. T., Pattison, S. L., Christensen, N., Armstrong, L. R., Brahmbhatt, V. N., Smolarczyk, K., Harrison, M. T., Costa, M., Mugridge, N. B., Sedliarou, I., Grimes, N. A., Kiss, D. L., Stillman, B., Hann, C. L., Gallia, G. L., Graham, R. M., Brahmbhatt, H. (April 2016) Targeted Doxorubicin Delivery to Brain Tumors via Minicells: Proof of Principle Using Dogs with Spontaneously Occurring Tumors as a Model. PLoS One, 11 (4). e0151832. ISSN 1932-6203 (Electronic)1932-6203 (Linking)

Mayo, L. D., Dixon, J. E., Durden, D. L., Tonks, N. K., Donner, D. B. (February 2002) PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. Journal of Biological Chemistry, 277 (7). pp. 5484-5489. ISSN 0021-9258

Morris, Van K, Kennedy, Erin B, Baxter, Nancy N, Benson, Al B, Cercek, Andrea, Cho, May, Ciombor, Kristen K, Cremolini, Chiara, Davis, Anjee, Deming, Dustin A, Fakih, Marwan G, Gholami, Sepideh, Hong, Theodore S, Jaiyesimi, Ishmael, Klute, Kelsey, Lieu, Christopher, Sanoff, Hanna, Strickler, John H, White, Sarah, Willis, Jason A, Eng, Cathy (January 2023) Treatment of Metastatic Colorectal Cancer: ASCO Guideline. Journal of Clinical Oncology, 41 (3). pp. 678-700. ISSN 0732-183X

Mousset, Alexandra, Lecorgne, Enora, Bourget, Isabelle, Lopez, Pascal, Jenovai, Kitti, Cherfils-Vicini, Julien, Dominici, Chloé, Rios, Géraldine, Girard-Riboulleau, Cédric, Liu, Bodu, Spector, David L, Ehmsen, Sidse, Renault, Shufang, Hego, Caroline, Mechta-Grigoriou, Fatima, Bidard, François-Clément, Terp, Mikkel Green, Egeblad, Mikala, Gaggioli, Cédric, Albrengues, Jean (April 2023) Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation. Cancer Cell, 41 (4). 757-775.e10. ISSN 1535-6108 (Public Dataset)

Mulloy, R., Ferrand, A., Kim, Y., Sordella, R., Bell, D. W., Haber, D. A., Anderson, K. S., Settleman, J. (March 2007) Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib. Cancer Research, 67 (5). pp. 2325-30. ISSN 0008-5472

Nakasone, E., Askautrud, H., Kees, T., Park, J., Fein, M., Egeblad, M. (February 2013) Imaging contributions of the microenvironment to chemoresistance. Journal of Nuclear Medicine, 54 (Supple). p. 31. ISSN 0161-5505

Nakasone, E. S., Askautrud, H. A., Kees, T., Park, J. H., Plaks, V., Ewald, A. J., Fein, M., Rasch, M. G., Tan, Y. X., Qiu, J., Park, J., Sinha, P., Bissell, M. J., Frengen, E., Werb, Z., Egeblad, M. (April 2012) Imaging Tumor-Stroma Interactions during Chemotherapy Reveals Contributions of the Microenvironment to Resistance. Cancer Cell, 21 (4). pp. 488-503. ISSN 1535-6108

Neesse, A., Frese, K. K., Bapiro, T. E., Nakagawa, T., Sternlicht, M. D., Seeley, T. W., Pilarsky, C., Jodrell, D. I., Spong, S. M., Tuveson, D. A. (July 2013) CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America, 110 (30). pp. 12325-30. ISSN 0027-8424

Neesse, A., Michl, P., Tuveson, D. A., Ellenrieder, V. (April 2014) nab-Paclitaxel: Novel Clinical and Experimental Evidence in Pancreatic Cancer. Zeitschrift fur Gastroenterologie, 52 (4). pp. 360-366. ISSN 0044-2771

Nielsen, Sebastian R, Strøbech, Jan E, Horton, Edward R, Jackstadt, Rene, Laitala, Anu, Bravo, Marina C, Maltese, Giorgia, Jensen, Adina RD, Reuten, Raphael, Rafaeva, Maria, Karim, Saadia A, Hwang, Chang-Il, Arnes, Luis, Tuveson, David A, Sansom, Owen J, Morton, Jennifer P, Erler, Janine T (June 2021) Suppression of tumor-associated neutrophils by lorlatinib attenuates pancreatic cancer growth and improves treatment with immune checkpoint blockade. Nature Communications, 12 (1). p. 3414. ISSN 2041-1723

Ortiz, Michael V, Ahmed, Saima, Burns, Melissa, Henssen, Anton G, Hollmann, Travis J, MacArthur, Ian, Gunasekera, Shehana, Gaewsky, Lyvia, Bradwin, Gary, Ryan, Jeremy, Letai, Anthony, He, Ying, Naranjo, Arlene, Chi, Yueh-Yun, LaQuaglia, Michael, Heaton, Todd, Cifani, Paolo, Dome, Jeffrey S, Gadd, Samantha, Perlman, Elizabeth, Mullen, Elizabeth, Steen, Hanno, Kentsis, Alex (August 2019) Prohibitin is a prognostic marker and therapeutic target to block chemotherapy resistance in Wilms’ tumor. JCI Insight, 4 (15). ISSN 2379-3708

Pardee, T., Zuber, J., Lowe, S. W. (November 2009) The Flt3 ITD Accelerates An Already Established Myeloid Leukemia and Alters Chemotherapy Response In Vitro and In Vivo in a p53 Dependent Manner. Blood, 114 (22). p. 685. ISSN 0006-4971

Pardee, T. S., Zuber, J., Lowe, S. W. (May 2009) Effects of the Flt3 ITD on response to chemotherapy in a murine model of acute myeloid leukemia. Journal of Clinical Oncology, 27 (15). p. 7060. ISSN 0732-183X

Pardee, T. S., Zuber, J., Lowe, S. W. (April 2011) Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner. Exp Hematol, 39 (4). 473-485 e4. ISSN 1873-2399 (Electronic)0301-472X (Linking)

Patel, S., von Mehren, M., Reed, D. R., Kaiser, P., Charlson, J., Ryan, C. W., Rushing, D., Livingston, M., Singh, A., Seth, R., Forscher, C., D'Amato, G., Chawla, S. P., McCarthy, S., Wang, G., Parekh, T., Knoblauch, R., Hensley, M. L., Maki, R. G., Demetri, G. D. (August 2019) Overall survival and histology-specific subgroup analyses from a phase 3, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarcoma or leiomyosarcoma. Cancer, 125 (15). pp. 2610-2620. ISSN 0008-543x

Piccart, Martine J, Hilbers, Florentine S, Bliss, Judith M, Caballero, Carmela, Frank, Elizabeth S, Renault, Patrick, Naït Kaoudjt, Rachida, Schumacher, Eva, Spears, Patricia A, Regan, Meredith M, Gelber, Richard D, Davidson, Nancy E, Norton, Larry, Winer, Eric P, BIG-NABCG Collaboration (December 2020) Road Map to Safe and Well-Designed De-escalation Trials of Systemic Adjuvant Therapy for Solid Tumors. Journal of Clinical Oncology, 38 (34). pp. 4120-4129. ISSN 0732-183X

Schmidt, Michael J, Naghdloo, Amin, Prabakar, Rishvanth K, Kamal, Mohamed, Cadaneanu, Radu, Garraway, Isla P, Lewis, Michael, Aparicio, Ana, Zurita-Saavedra, Amado, Corn, Paul, Kuhn, Peter, Pienta, Kenneth J, Amend, Sarah R, Hicks, James (November 2024) Polyploid cancer cells reveal signatures of chemotherapy resistance. Oncogene. ISSN 0950-9232 (Public Dataset)

Schmitt, C. A., Fridman, J., Lowe, S. W. (July 2000) Molecular genetics of drug sensitivity and resistance in a mouse lymphoma model. British Journal of Cancer, 83. p. 4. ISSN 0007-0920

Schmitt, C. A., Lowe, S. W. (April 2001) Apoptosis is critical for drug response in vivo. Drug Resistance Updates, 4 (2). pp. 132-134. ISSN 1368-7646

Schmitt, C. A., Wallace-Brodeur, R. R., Rosenthal, C. T., McCurrach, M. E., Lowe, S. W. (2000) DNA damage responses and chemosensitivity in the E mu-myc mouse lymphoma model. Cold Spring Harbor Symposia on Quantitative Biology, 65. pp. 499-510. ISSN 0091-7451

Schmitt, C. A., Yang, M., Fridman, J. S., Baranov, E., Hoffman, R. M., Lowe, S. W. (November 2001) Myc-driven lymphomas respond with both apoptosis and senescence to anticancer treatment in vivo. Blood, 98 (11). 172B-172B. ISSN 0006-4971

Seppälä, Toni T, Zimmerman, Jacquelyn W, Sereni, Elisabetta, Plenker, Dennis, Suri, Reecha, Rozich, Noah, Blair, Alex, Thomas, Dwayne L, Teinor, Jonathan, Javed, Ammar, Patel, Hardik, Cameron, John L, Burns, William R, He, Jin, Tuveson, David A, Jaffee, Elizabeth M, Eshleman, James, Szabolcs, Annamaria, Ryan, David P, Ting, David T, Wolfgang, Christopher L, Burkhart, Richard A (September 2020) Patient-derived Organoid Pharmacotyping is a Clinically Tractable Strategy for Precision Medicine in Pancreatic Cancer. Annals of Surgery, 272 (3). pp. 427-435. ISSN 0003-4932

Seppälä, Toni T, Zimmerman, Jacquelyn W, Suri, Reecha, Zlomke, Haley, Ivey, Gabriel D, Szabolcs, Annamaria, Shubert, Christopher R, Cameron, John L, Burns, William R, Lafaro, Kelly J, He, Jin, Wolfgang, Christopher L, Zou, Ying S, Zheng, Lei, Tuveson, David A, Eshlemann, James R, Ryan, David P, Kimmelman, Alec C, Hong, Theodore S, Ting, David T, Jaffee, Elizabeth M, Burkhart, Richard A (April 2022) Precision medicine in pancreatic cancer: Patient derived organoid pharmacotyping is a predictive biomarker of clinical treatment response. Clinical Cancer Research. ISSN 1078-0432

Sharib, Jeremy M, Creasy, John M, Wildman-Tobriner, Benjamin, Kim, Charles, Uronis, Hope, Hsu, Shiaowen David, Strickler, John H, Gholami, Sepideh, Cavnar, Michael, Merkow, Ryan P, Kingham, Peter, Kemeny, Nancy, Zani, Sabino, Jarnagin, William R, Allen, Peter J, D'Angelica, Michael I, Lidsky, Michael E (December 2022) Hepatic Artery Infusion Pumps: A Surgical Toolkit for Intraoperative Decision-Making and Management of Hepatic Artery Infusion-Specific Complications. Annals of Surgery, 276 (6). pp. 943-956. ISSN 0003-4932

Stacchiotti, S., Mir, O., Le Cesne, A., Vincenzi, B., Fedenko, A., Maki, R. G., Somaiah, N., Patel, S., Brahmi, M., Blay, J. Y., Boye, K., Sundby Hall, K., Gelderblom, H., Hindi, N., Martin-Broto, J., Kosela, H., Rutkowski, P., Italiano, A., Duffaud, F., Kobayashi, E., Casali, P. G., Provenzano, S., Kawai, A. (January 2018) Activity of Pazopanib and Trabectedin in Advanced Alveolar Soft Part Sarcoma. Oncologist, 23 (1). pp. 62-70. ISSN 1083-7159

Standring, Oliver, Gholami, Sepideh (September 2023) Adjuvant hepatic artery infusion pump chemotherapy for resected colorectal cancer liver metastases. Surgery, 174 (3). pp. 747-749. ISSN 0039-6060

Stebbing, J., Paz, K., Schwartz, G. K., Wexler, L. H., Maki, R., Pollock, R. E., Morris, R., Cohen, R., Shankar, A., Blackman, G., Harding, V., Vasquez, D., Krell, J., Zacharoulis, S., Ciznadija, D., Katz, A., Sidransky, D. (July 2014) Patient-derived xenografts for individualized care in advanced sarcoma. Cancer, 120 (13). pp. 2006-15. ISSN 1097-0142 (Electronic)0008-543X (Linking)

Sugarman, R., Patel, R., Sharma, S., Plenker, D., Tuveson, D., Saif, M. W. (July 2019) Pharmacokinetics and pharmacodynamics of new drugs for pancreatic cancer. Expert Opin Drug Metab Toxicol, 15 (7). pp. 541-552. ISSN 1742-5255

Szybalski, Waclaw T. (1953) Multiple chemotherapy and antagonism between antimicrobial agents. Proceedings of the Sixth International Congress on Microbiology, 1 (213).

Tawbi, H. A., Burgess, M., Bolejack, V., Van Tine, B. A., Schuetze, S. M., Hu, J., D'Angelo, S., Attia, S., Riedel, R. F., Priebat, D. A., Movva, S., Davis, L. E., Okuno, S. H., Reed, D. R., Crowley, J., Butterfield, L. H., Salazar, R., Rodriguez-Canales, J., Lazar, A. J., Wistuba, II, Baker, L. H., Maki, R. G., Reinke, D., Patel, S. (November 2017) Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial. Lancet Oncol, 18 (11). pp. 1493-1501. ISSN 1470-2045

Williams, Edward H, Flint, Thomas R, Connell, Claire M, Giglio, Daniel, Lee, Hassal, Ha, Taehoon, Gablenz, Eva, Bird, Nicholas J, Weaver, James MJ, Potts, Harry, Whitley, Cameron T, Bookman, Michael A, Lynch, Andy G, Meyer, Hannah V, Tavaré, Simon, Janowitz, Tobias (March 2021) CamGFR v2: A New Model for Estimating the Glomerular Filtration Rate from Standardized or Non-standardized Creatinine in Patients with Cancer. Clinical Cancer Research, 27 (5). pp. 1381-1390. ISSN 1078-0432

Wong, Willard, Brogi, Edi, Reis-Filho, Jorge S, Plitas, George, Robson, Mark, Norton, Larry, Morrow, Monica, Wen, Hannah Y (July 2021) Poor response to neoadjuvant chemotherapy in metaplastic breast carcinoma. npj Breast Cancer, 7 (1). p. 96. ISSN 2374-4677

Wrzeszczynski, K. O., Fan, G. F., Fu, C. X., Pappin, D. J., Lucito, R., Tonks, N. K. (April 2013) Proteomic identification of carboplatin resistance in ovarian cancer cells. Cancer Research, 73 (8 Supp). p. 2502. ISSN 0008-5472

Yin, Bin, Kogan, Scott C., Dickins, Ross A., Lowe, Scott W., Largaespada, David A. (2006) Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia. Experimental Hematology, 34 (5). pp. 631-641. ISSN 0301472X

Yohe, M. E., Heske, C. M., Stewart, E., Adamson, P. C., Ahmed, N., Antonescu, C. R., Chen, E., Collins, N., Ehrlich, A., Galindo, R. L., Gryder, B. E., Hahn, H., Hammond, S., Hatley, M. E., Hawkins, D. S., Hayes, M. N., Hayes-Jordan, A., Helman, L. J., Hettmer, S., Ignatius, M. S., Keller, C., Khan, J., Kirsch, D. G., Linardic, C. M., Lupo, P. J., Rota, R., Shern, J. F., Shipley, J., Sindiri, S., Tapscott, S. J., Vakoc, C. R., Wexler, L. H., Langenau, D. M. (June 2019) Insights into pediatric rhabdomyosarcoma research: Challenges and goals. Pediatr Blood Cancer, 66 (10). article no. e27869. ISSN 1545-5009

Zuber, J., Radtke, I., Pardee, T. S., Zhao, Z., Rappaport, A. R., Luo, W., McCurrach, M. E., Yang, M. M., Dolan, M. E., Kogan, S. C., Downing, J. R., Lowe, S. W. (April 2009) Mouse models of human AML accurately predict chemotherapy response. Genes Dev, 23 (7). pp. 877-89.

Conference or Workshop Item

Chawla, S. P., Van Tine, B. A., Pollack, S., Ganjoo, K. N., Elias, A. D., Riedel, R. F., Attia, S., Choy, E., Okuno, S. H., Agulnik, M., von Mehren, M., Livingston, M. B., Keedy, V. L., Verschraegen, C. F., Philip, T., Bohac, G. C., Yurasov, S., Lu, H. L., Chen, M., Maki, R. G. (May 2019) A phase II randomized study of CMB305 and atezolizumab versus atezolizumab in NY-ESO-1(+) soft tissue sarcoma: Analysis of immunogenicity, tumor control, and patient survival. In: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO).

Demyan, Lyudmyla, Standring, Oliver, Chung, Taemoon, Gazzara, Emma, Lyons, Scott, Park, Youngkyu, King, Daniel, Jonas, Oliver, Tuveson, David, Weiss, Matthew (2023) Feasibility of Implantable Microdosing Devices to Perform in vivo Pharmacotyping in Pancreatic Cancer. In: Annual International Conference of the Society-of-Surgical-Oncology (SSO) on Surgical Cancer Care, MAR 22-25, 2023, Boston, MA.

Gao, ChongFeng, Wisniewski, Luke, Liu, Ying, Staal, Ben, Beddows, Ian, Plenker, Dennis, Aldakkak, Mohammed, Hall, Johnathan, Barnett, Daniel, Gouda, Mirna Kheir, Allen, Peter, Drake, Richard, Zureikat, Amer, Huang, Ying, Evans, Douglas, Singhi, Aatur, Brand, Randall, Tuveson, David, Tsai, Susan, Haab, Brian (September 2020) Detection of chemotherapy-resistant pancreatic cancer using a glycan Biomarker. In: AACR Virtual Special Conference on Pancreatic Cancer.

Khosravi, Pegah, Sutton, Elizabeth J, Jee, Justin, Dalfonso, Timothy, Fong, Christopher J, Rose, Doori, Da Silva, Edaise M, Kohli, Armaan, Ho, David Joon, Ahmed, Mehnaj S, Martinez, Danny, Begum, Anika, Zakszewski, Elizabeth, Aukerman, Andrew, Tazi, Yanis, Pinker-Domenig, Katja, Eskreis-Winkler, Sarah, Khan, Atif J, Brogi, Edi, Morris, Elizabeth, Chandarlapaty, Sarat, Plitas, George, Powell, Simon, Morrow, Monica, Norton, Larry, Gao, Jianjiong, Robson, Mark, Zhang, Hong, Shah, Sohrab, Razavi, Pedram (2022) Prediction of neoadjuvant treatment outcomes with multimodal data integration in breast cancer. In: American Association for Cancer Research Annual Meeting 2022, 2022 Apr 8-13, Philadelphia, PA.

Thesis

Burgess, D. J. (2007) RNAi Genetic Screens for Chemotherapy Response Modifier Genes. PhD thesis, Cold Spring Harbor Laboratory.

Nakasone, Elizabeth (March 2012) A Stromal CCL2/CCR2 Signaling Axis Regulates Chemotherapeutic Response in a Mouse Model of Breast Cancer. PhD thesis, Cold Spring Harbor Laboratory.