Items where Subject is "organs, tissues, organelles, cell types and functions > cell types and functions > cell functions > senescence"

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Number of items at this level: 40.

A

Aksoy, O., Chicas, A., Zeng, T., Zhao, Z., McCurrach, M., Wang, X., Lowe, S. W. (July 2012) The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence. Genes Dev, 26 (14). pp. 1546-57. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Alcorta, D. A., Xiong, Y., Phelps, D., Hannon, G., Beach, D., Barrett, J. C. (November 1996) Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America, 93 (24). pp. 13742-13747. ISSN 00278424 (ISSN)

Alimonti, A., Nardella, C., Chen, Z., Clohessy, J. G., Carracedo, A., Trotman, L. C., Cheng, K., Varmeh, S., Kozma, S. C., Thomas, G., Rosivatz, E., Woscholski, R., Cognetti, F., Scher, H. I., Pandolfi, P. P. (March 2010) A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis. Journal of Clinical Investigation, 120 (3). pp. 681-693. ISSN 00219738 (ISSN)

Aloy, P., Gavin, A. C., Ideker, T., Walhout, M. (August 2010) SYSTEMS BIOLOGY: NETWORKS. In: Joint Cold Spring Harbor Laboratory/Wellcome Trust Conference on SYSTEMS BIOLOGY: NETWORKS, August 11–August 15, 2010, Wellcome Trust Conference Center, Hixton UK.

B

Beausejour, C. M., Krtolica, A., Galimi, F., Narita, M., Lowe, S. W., Yaswen, P., Campisi, J. (August 2003) Reversal of human cellular senescence: roles of the p53 and p16 pathways. Embo Journal, 22 (16). pp. 4212-4222. ISSN 0261-4189

Bihani, Teeru, Chicas, Agustin, Lo, Crystal Pui-Kwan, Lin, Athena W. (January 2007) Dissecting the senescence-like program in tumor cells activated by Ras signaling. Journal of Biological Chemistry, 282 (4). pp. 2666-2675. ISSN 0021-9258

C

Chen, Z., Trotman, L. C., Shaffer, D., Lin, H. K., Dotan, Z. A., Niki, M., Koutcher, J. A., Scher, H. I., Ludwig, T., Gerald, W., Cordon-Cardo, C., Pandolfi, P. P. (August 2005) Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature, 436 (7051). pp. 725-30. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Chicas, A., Kapoor, A., Wang, X. W., Aksoy, O., Evertts, A. G., Zhang, M. Q., Garcia, B. A., Bernstein, E., Lowe, S. W. (June 2012) H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence. Proceedings of the National Academy of Sciences of the United States of America, 109 (23). pp. 8971-8976. ISSN 0027-8424

Chien, Y., Scuoppo, C., Wang, X., Fang, X., Balgley, B., Bolden, J. E., Premsrirut, P., Luo, W., Chicas, A., Lee, C. S., Kogan, S. C., Lowe, S. W. (October 2011) Control of the senescence-associated secretory phenotype by NF-kappaB promotes senescence and enhances chemosensitivity. Genes Dev, 25 (20). pp. 2125-36. ISSN 1549-5477 (Electronic) 0890-9369 (Linking)

Cifra, A., Lowe, S.W (November 2015) Exploring cell apoptosis and senescence to understand and treat cancer: an interview with Scott Lowe. Dis Model Mech, 8 (11). pp. 1345-8. ISSN 1754-8411 (Electronic)1754-8403 (Linking)

D

Das, S., Fregoso, O. I., Krainer, A. R. (2013) A new path to oncogene-induced senescence: At the cross-roads of splicing and translation. Cell Cycle, 12 (10). ISSN 1551-4005 (Electronic)1551-4005 (Linking)

F

Ferbeyre, G., De Stanchina, E., Lin, A. W., Querido, E., McCurrach, M. E., Hannon, G. J., Lowe, S. W. (2002) Oncogenic ras and p53 cooperate to induce cellular senescence. Molecular and Cellular Biology, 22 (10). pp. 3497-3508. ISSN 02707306 (ISSN)

Ferbeyre, G., de Stanchina, E., Querido, E., Baptiste, N., Prives, C., Lowe, S. W. (August 2000) PML is induced by oncogenic ras and promotes premature senescence. Genes & Development, 14 (16). pp. 2015-2027. ISSN 0890-9369

Fregoso, O. I., Das, S., Akerman, M., Krainer, A. R. (March 2013) Splicing-Factor Oncoprotein SRSF1 Stabilizes p53 via RPL5 and Induces Cellular Senescence. Molecular Cell, 50 (1). pp. 56-66. ISSN 1097-2765

G

Greider, C. W. (August 1990) Telomeres, telomerase and senescence. Bioessays, 12 (8). pp. 363-9. ISSN 0265-9247 (Print)0265-9247 (Linking)

Guo, X., Keyes, W. M., Papazoglu, C., Zuber, J., Li, W., Lowe, S. W., Vogel, H., Mills, A. A. (December 2009) TAp63 induces senescence and suppresses tumorigenesis in vivo. Nat Cell Biol, 11 (12). 1451–1457.

Guo, X. C., Mills, A. A. (February 2007) p63, cellular senescence and tumor development. Cell Cycle, 6 (3). pp. 305-11. ISSN 1538-4101

K

Keyes, W. M., Mills, A. A. (February 2006) p63: a new link between senescence and aging. Cell Cycle, 5 (3). pp. 260-265. ISSN 15384101

Krizhanovsky, V., Xue, W., Zender, L., Yon, M., Hernando, E., Lowe, S. W. (2008) Implications of cellular senescence in tissue damage response, tumor suppression, and stem cell biology. Cold Spring Harb Symp Quant Biol, 73. pp. 513-22.

Krizhanovsky, V., Yon, M., Dickens, R. A., Hearn, S. A., Simon, J., Ma, B., Miething, C., Zender, L., Lowe, S. W. (August 2008) Senescence of activated stellate cells limits liver fibrosis. Cell, 134 (4). 657-667 .

L

Lin, A. W., Barradas, M., Stone, J. C., Van Aelst, L., Serrano, M., Lowe, S. W. (October 1998) Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes & Development, 12 (19). pp. 3008-3019. ISSN 0890-9369

Lira, B. S., Gramegna, G., Trench, B., Alves, F. R. R., Silva, E. M., Silva, G. F. F., Thirumalaikumar, V. P., Lupi, A. C. D., Demarco, D., Purgatto, E., Nogueira, F. T., Balazadeh, S., Freschi, L., Rossi, M. (July 2017) Manipulation of a senescence-associated gene improves fleshy fruit yield. Plant Physiol. ISSN 0032-0889

Lowe, S. W. (October 2002) Premature senescence in tumor suppression. Cancer Epidemiology Biomarkers & Prevention, 11 (10). 1259S-1259S. ISSN 1055-9965

Lowe, S. W. (June 2010) Roles and regulation of cellular senescence. Ejc Supplements, 8 (5). p. 20. ISSN 1359-6349

N

Narita, M., Lowe, S. W. (March 2004) Executing cell senescence. Cell Cycle, 3 (3). pp. 244-6. ISSN 1538-4101 (Print)

Narita, M., Narita, M., Krizhanovsky, V., Nunez, S., Chicas, A., Hearn, S. A., Myers, M. P., Lowe, S. W. (August 2006) A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation. Cell, 126 (3). pp. 503-14. ISSN 0092-8674 (Print)

Narita, M., Nunez, S., Heard, E., Narita, M., Lin, A. W., Hearn, S. A., Spector, D. L., Hannon, G. J., Lowe, S. W. (June 2003) Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell, 113 (6). pp. 703-716. ISSN 0092-8674

O

Ori, N., Juarez, M. T., Jackson, D. P, Yamaguchi, J., Banowetz, G. M., Hake, S. (1999) Leaf senescence is delayed in tobacco plants expressing the maize homeobox gene knotted1 under the control of a senescence-activated promoter. Plant Cell, 11 (6). pp. 1073-1080. ISSN 10404651 (ISSN)

P

Papazoglu, C., Mills, A. A. (January 2007) p53: At the crossroad between cancer and ageing. Journal of Pathology, 211 (2). pp. 124-133. ISSN 0022-3417

S

Sagiv, A., Biran, A., Yon, M., Simon, J., Lowe, S. W., Krizhanovsky, V. (April 2013) Granule exocytosis mediates immune surveillance of senescent cells. Oncogene, 32 (15). pp. 1971-7. ISSN 1476-5594 (Electronic)0950-9232 (Linking)

Schmitt, C. A., Fridman, J. S., Yang, M., Lee, S., Baranov, E., Hoffman, R. M., Lowe, S. W. (May 2002) A senescence program controlled by p53 and p16(INK4a) contributes to the outcome of cancer therapy. Cell, 109 (3). pp. 335-346. ISSN 0092-8674

Schmitt, C. A., Yang, M., Fridman, J. S., Baranov, E., Hoffman, R. M., Lowe, S. W. (November 2001) Myc-driven lymphomas respond with both apoptosis and senescence to anticancer treatment in vivo. Blood, 98 (11). 172B-172B. ISSN 0006-4971

T

Tasdemir, N., Banito, A., Roe, J. S., Alonso-Curbelo, D., Camiolo, M., Tschaharganeh, D. F., Huang, C. H., Aksoy, O., Bolden, J. E., Chen, C. C., Fennell, M., Thapar, V., Chicas, A., Vakoc, C. R., Lowe, S. W. (June 2016) BRD4 connects enhancer remodeling to senescence immune surveillance. Cancer Discov, 6 (6). pp. 612-629. ISSN 2159-8290 (Electronic)2159-8274 (Linking)

Tasdemir, N., Lowe, S. W. (June 2013) Senescent cells spread the word: non-cell autonomous propagation of cellular senescence. Embo Journal, 84 (1). pp. 114-127. ISSN 0261-4189

Tasdemir, N. (August 2014) Investigating the role of Brd4 in cellular senescence and normal tissue homeostatsis. PhD thesis, Cold Spring Harbor Laboratory.

W

Wall, M., Poortinga, G., Stanley, K. L., Lindemann, R. K., Bots, M., Chan, C. J., Bywater, M. J., Kinross, K. M., Astle, M. V., Waldeck, K., Hannan, K. M., Shortt, J., Smyth, M. J., Lowe, S. W., Hannan, R. D., Pearson, R. B., Johnstone, R. W., McArthur, G. A. (January 2013) The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence. Cancer Discovery, 3 (1). pp. 82-95. ISSN 21598274

White, E., Lowe, S. W. (April 2009) Eating to exit: autophagy-enabled senescence revealed. Genes Dev, 23 (7). pp. 784-787. ISSN 0890-9369

Y

Yang, M., Haase, A. D., Huang, F. K., Coulis, G., Rivera, K. D., Dickinson, B. C., Chang, C. J., Pappin, D. J., Neubert, T. A., Hannon, G. J., Boivin, B., Tonks, N. K. (August 2014) Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence. Mol Cell, 55 (5). pp. 782-790. ISSN 1097-2765

Z

Zender, L., Xue, W., Cordon-Cardo, C., Lowe, S. W. (October 2006) P53 restoration in liver carcinomas induces cellular senescence and tumor clearance through an innate immune response. Hepatology, 44 (4). 694A-695A. ISSN 0270-9139

Zhang, Y., Shin, S. J., Liu, D., Ivanova, E., Foerster, F., Ying, H., Zheng, H., Xiao, Y., Chen, Z., Protopopov, A., Depinho, R. A., Paik, J. H. (June 2013) ZNF365 Promotes Stability of Fragile Sites and Telomeres. Cancer Discovery, 3 (7). pp. 798-811. ISSN 21598274

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