Items where Subject is "diseases & disorders > cancer > cancer types > lung cancer"

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Number of items at this level: 45.

A

Abera, M., Sordella, R., Kazanietz, M. (2013) PKC alpha is implicated in epithelial to mesenchymal transition and erlotinib resistance in non-small cell lung carcinoma cells. Cancer Research, 73 (8 (Sup). p. 5261. ISSN 0008-5472

Agrusa, C. J., Sordella, R., Paul, S., Lee, P. C., Port, J., Altorki, N. K., Stiles, B. M. (2014) A Novel Platform for Proteomic Analysis of Proximal Source Pulmonary Venous Blood Identifies Potential Biomarkers for Non-Small Cell Lung Cancer (NSCLC). Journal of the American College of Surgeons, 219 (3 Supp). S37-S37. ISSN 1072-7515

B

Bell, D. W., Brannigan, B. W., Matsuo, K., Finkelstein, D. M., Sordella, R., Settleman, J., Mitsudomi, T., Haber, D. A. (2008) Increased prevalence of EGFR-mutant lung cancer in women and in East Asian populations: analysis of estrogen-related polymorphisms. Clinical Cancer Research, 14 (13). pp. 4079-84. ISSN 1078-0432

Bell, D. W., Gore, I., Okimoto, R. A., Godin-Heymann, N., Sordella, R., Mulloy, R., Sharma, S. V., Brannigan, B. W., Mohapatra, G., Settleman, J., Haber, D. A. (2005) Inherited susceptibility to lung cancer may be associated with the T790M drug resistance mutation in EGFR. Nature Genetics, 37 (12). pp. 1315-6. ISSN 1061-4036

Bell, D. W., Sordella, R., Kwak, E. L., Godin-Heymann, N., Sharma, S. V., Sgroi, D. C., Sequist, L. V., Lynch, T. J., Settleman, J., Haber, D. A. (2006) Molecular targeted therapy of lung cancer. Tumor Biology, 27 (Suppl). ISSN 1010-4283

Berger, A. H., Chen, M., Morotti, A., Janas, J. A., Niki, M., Bronson, R. T., Taylor, B. S., Ladanyi, M., Van Aelst, L., Politi, K., Varmus, H. E., Pandolfi, P. P. (2013) DOK2 inhibits EGFR-mutated lung adenocarcinoma. PLoS One, 8 (11). e79526. ISSN 1932-6203

Bivona, T. G., Hieronymus, H., Parker, J., Chang, K., Taron, M., Rosell, R., Moonsamy, P., Dahlman, K., Miller, V. A., Costa, C., Hannon, G. J., Sawyers, C. L. (2011) FAS and NF-kappa B signalling modulate dependence of lung cancers on mutant EGFR. Nature, 471 (7339). pp. 523-526. ISSN 0028-0836

C

Castanon, E., Soltermann, A., Lopez, I., Ecay, M., Collantes, M., Picazo, J. M. L., Ponz, M., Rolfo, C., Calvo, A., Gil-Bazo, I. (2014) Inhibitor of differentiation 1 (Id1) expression in lung cancer cells and liver microenvironment is required for liver metastasis (LM) development from non-small cell lung cancer (NSCLC) by regulating EMT-related and proliferation-related proteins. European Journal of Cancer, 50. p. 65. ISSN 0959-8049

Chaudhri, V. K., Salzler, G. G., Dick, S. A., Buckman, M. S., Sordella, R., Karoly, E. D., Mohney, R., Stiles, B. M., Elemento, O., Altorki, N. K., McGraw, T. E. (2013) Metabolic Alterations in Lung Cancer-Associated Fibroblasts Correlated with Increased Glycolytic Metabolism of the Tumor. Molecular Cancer Research, 11 (6). pp. 579-592. ISSN 1541-7786

Chen, M. H., Herzka, T. M., Zeeman, M. E., Plafker, K. S., Minderer, M., Castillo-Martin, M., Cordon-Cardo, C., Plafker, S. M., Trotman, L. C. (2013) PTEN levels are controlled by a nuclear transport receptor in lung cancer. Cancer Research, 73 (8 (Sup). p. 5258. ISSN 0008-5472

Coppolino, A., Agrusa, C. J., Kajno, E., Ryu, S., Sordella, R., Altorki, N. K., Stiles, B. M. (2014) Bone Marrow Induces STAT3 Pathway Activation in a Model of Disseminated Non-Small Cell Lung Cancer Cells. Journal of the American College of Surgeons, 219 (3 Supp). S31-S31. ISSN 1072-7515

Coppolino, A., Gao, D. C., Wagner, P. L., Sordella, R., Mittal, V., Altorki, N. K., Stiles, B. M. (2012) Standard markers for detection of circulating tumor cells are variably expressed in pulmonary adenocarcinomas and are downregulated in cells undergoing mesenchymal transition. Journal of the American College of Surgeons, 215 (3). S40-S40. ISSN 1072-7515

F

Flinterman, M. B., Mymryk, J. S., Klanrit, P., Yousef, A. F., Lowe, S. W., Caldas, C., Gaken, J., Farzaneh, F., Tavassoli, M. (2007) p400 function is required for the adenovirus E1A-mediated suppression of EGFR and tumour cell killing. Oncogene, 26 (48). pp. 6863-6874. ISSN 0950-9232

G

Gupta, G. P., Perk, J., Acharyya, S., de Candia, P., Mittal, V., Todorova-Manova, K., Gerald, W. L., Brogi, E., Benezra, R., Massague, J. (2007) ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proc Natl Acad Sci U S A, 104 (49). pp. 19506-11. ISSN 1091-6490 (Electronic)

Gutschner, T., Hammerle, M., Eissmann, M., Hsu, J., Kim, Y., Hung, G. N., Revenko, A., Arun, G., Stentrup, M., Gross, M., Zornig, M., MacLeod, A. R., Spector, D. L., Diederichs, S. (2013) The long non-coding RNA MALAT1 is an essential gene regulator for lung cancer metastasis in a novel human knockout model. Cancer Research, 73 (8 (Sup). p. 1121. ISSN 0008-5472

Gutschner, T., Hammerle, M., Eißmann, M., Hsu, J., Kim, Y., Hung, G., Revenko, A., Arun, G., Stentrup, M., Groß, M., Zörnig, M., MacLeod, A. R., Spector, D. L., Diederichs, S. (2013) The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Research, 73 (3). pp. 1180-1189. ISSN 00085472 (ISSN)

H

Haber, D. A., Bell, D. W., Sordella, R., Kwak, E. L., Godin-Heymann, N., Sharma, S. V., Lynch, T. J., Settleman, J. (2005) Molecular targeted therapy of lung cancer: EGFR mutations and response to EGFR inhibitors. Cold Spring Harbor Symposia on Quantitative Biology, 70. pp. 419-26. ISSN 0091-7451

Hsu, D. S., Acharya, C. R., Balakumaran, B. S., Riedel, R. F., Kim, M. K., Stevenson, M., Tuchman, S., Mukherjee, S., Barry, W., Dressman, H. K., Nevins, J. R., Powers, S., Mu, D., Potti, A. (2009) Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer. Proc Natl Acad Sci U S A, 106 (13). pp. 5312-5317. ISSN 0027-8424 (Print)1091-6490 (Electronic)

K

Kani, K., Sordella, R., Mallick, P. (2012) Investigation of acquired resistance to EGFR-targeted therapies in lung cancer using cDNA microarrays. Methods in Molecular Biology, 795. pp. 233-53. ISSN 1940-6029 (Electronic)1064-3745 (Linking)

Kendall, J. T., Liu, Q. A., Bakleh, A., Krasnitz, A., Nguyen, K. C. Q., Lakshmi, B., Gerald, W., Powers, S., Mu, D. (2007) Oncogenic cooperation and coamplification of developmental transcription factor genes in lung cancer. Proc Natl Acad Sci U S A, 104 (42). pp. 16663-16668. ISSN 0027-8424 (Print)

Kwak, E. L., Bang, Y. J., Camidge, D. R., Shaw, A. T., Solomon, B., Maki, R. G., Ou, S. H., Dezube, B. J., Janne, P. A., Costa, D. B., Varella-Garcia, M., Kim, W. H., Lynch, T. J., Fidias, P., Stubbs, H., Engelman, J. A., Sequist, L. V., Tan, W., Gandhi, L., Mino-Kenudson, M., Wei, G. C., Shreeve, S. M., Ratain, M. J., Settleman, J., Christensen, J. G., Haber, D. A., Wilner, K., Salgia, R., Shapiro, G. I., Clark, J. W., Iafrate, A. J. (2010) Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med, 363 (18). pp. 1693-703. ISSN 1533-4406 (Electronic)0028-4793 (Linking)

Kwak, E. L., Sordella, R., Bell, D. W., Godin-Heymann, N., Okimoto, R. A., Brannigan, B. W., Harris, P. L., Driscoll, D. R., Fidias, P., Lynch, T. J., Rabindran, S. K., McGinnis, J. P., Wissner, A., Sharma, S. V., Isselbacher, K. J., Settleman, J., Haber, D. A. (2005) Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib. Proceedings of the National Academy of Sciences of the United States of America, 102 (21). pp. 7665-70. ISSN 0027-8424

L

Li, J., Sordella, R., Powers, S. (2016) Effectors and potential targets selectively upregulated in human KRAS-mutant lung adenocarcinomas. Sci Rep, 6. p. 27891. ISSN 2045-2322 (Electronic)2045-2322 (Linking)

Liu-Sullivan, N., Zhang, J., Bakleh, A., Marchica, J., Li, J., Siolas, D., Laquerre, S., Degenhardt, Y. Y., Wooster, R., Chang, K., Hannon, G. J., Powers, S. (2011) Pooled shRNA screen for sensitizers to inhibition of the mitotic regulator polo-like kinase (PLK1). Oncotarget, 2 (12). pp. 1254-64. ISSN 1949-2553 (Electronic) 1949-2553 (Linking)

Lynch, T. J., Bell, D. W., Sordella, R., Gurubhagavatula, S., Okimoto, R. A., Brannigan, B. W., Harris, P. L., Haserlat, S. M., Supko, J. G., Haluska, F. G., Louis, D. N., Christiani, D. C., Settleman, J., Haber, D. A. (2004) Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. The New England Journal of Medicine, 350 (21). pp. 2129-39. ISSN 1533-4406 (Electronic)

Lyons, S. K., Meuwissen, R., Krimpenfort, P., Berns, A. (2003) The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice. Cancer Res, 63 (21). pp. 7042-6. ISSN 0008-5472 (Print)0008-5472 (Linking)

M

Manchado, E., Weissmueller, S., Morris, J. P., Chen, C. C., Wullenkord, R., Lujambio, A., de Stanchina, E., Poirier, J. T., Gainor, J. F., Corcoran, R. B., Engelman, J. A., Rudin, C. M., Rosen, N., Lowe, S. W. (2016) A combinatorial strategy for treating KRAS-mutant lung cancer. Nature, 534. pp. 647-51. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

McFadden, D. G., Politi, K., Bhutkar, A., Chen, F. K., Song, X., Pirun, M., Santiago, P. M., Kim-Kiselak, C., Platt, J. T., Lee, E., Hodges, E., Rosebrock, A. P., Bronson, R. T., Socci, N. D., Hannon, G. J., Jacks, T., Varmus, H. (2016) Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma. Proc Natl Acad Sci U S A, 113 (42). E6409-E6417. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Mulloy, R., Ferrand, A., Kim, Y., Sordella, R., Bell, D. W., Haber, D. A., Anderson, K. S., Settleman, J. (2007) Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib. Cancer Research, 67 (5). pp. 2325-30. ISSN 0008-5472

O

Okamoto, A., Hussain, S. P., Hagiwara, K., Spillare, E. A., Rusin, M. R., Demetrick, D. J., Serrano, M., Hannon, G. J., Shiseki, M., Zariwala, M., Xiong, Y., Beach, D. H., Yokota, J., Harris, C. C. (1995) Mutations in the p16(INK4)/MTS1/CDKN2, p15(INK4B)/MTS2, and p18 genes in primary and metastatic lung cancer. Cancer Research, 55 (7). pp. 1448-1451. ISSN 00085472 (ISSN)

Oliver, T. G., Mercer, K. L., Sayles, L. C., Burke, J. R., Mendus, D., Lovejoy, K. S., Cheng, M. H., Subramanian, A., Mu, D., Powers, S., Crowley, D., Bronson, R. T., Whittaker, C. A., Bhutkar, A., Lippard, S. J., Golub, T., Thomale, J., Jacks, T., Sweet-Cordero, E. A. (2010) Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes & Development, 24 (8). pp. 837-852. ISSN 0890-9369

Ou, S. H., Bazhenova, L., Camidge, D. R., Solomon, B. J., Herman, J., Kain, T., Bang, Y. J., Kwak, E. L., Shaw, A. T., Salgia, R., Maki, R. G., Clark, J. W., Wilner, K. D., Iafrate, A. J. (2010) Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer. J Thorac Oncol, 5 (12). pp. 2044-6. ISSN 1556-1380 (Electronic)1556-0864 (Linking)

Ou, S. H., Kwak, E. L., Siwak-Tapp, C., Dy, J., Bergethon, K., Clark, J. W., Camidge, D. R., Solomon, B. J., Maki, R. G., Bang, Y. J., Kim, D. W., Christensen, J., Tan, W., Wilner, K. D., Salgia, R., Iafrate, A. J. (2011) Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification. J Thorac Oncol, 6 (5). pp. 942-6. ISSN 1556-1380 (Electronic)1556-0864 (Linking)

P

Pineda, Maria L (2012) Substrate specificity of receptor tyrosine kinases is critical for selective signaling. PhD thesis, Cold Spring Harbor Laboratory.

Powers, S., Mu, D. (2008) Genetic similarities between organogenesis and tumorigenesis of the lung. Cell Cycle, 7 (2). 200 - 204 .

R

Reed, M. F., Zagorski, W. A., Howington, J. A., Zilfou, J. T., Knudsen, E. S. (2006) Inhibition of Retinoblastoma Tumor Suppressor Activity by RNA Interference in Lung Cancer Lines. Annals of Thoracic Surgery, 82 (1). pp. 249-253. ISSN 00034975

Rodriguez, E., Mannion, L., D'Santos, P., Griffiths, M., Arends, M. J., Brindle, K. M., Lyons, S. K. (2014) Versatile and enhanced tumour modelling in mice via somatic cell transduction. J Pathol, 232 (4). pp. 449-57. ISSN 1096-9896 (Electronic)0022-3417 (Linking)

Rollins, F. (2011) The genetics and epigenetics of erlotinib resistance in non-small cell lung cancer. PhD thesis, Cold Spring Harbor Laboratory.

S

Shaw, Alice T., Yeap, Beow Y., Solomon, Benjamin J., Riely, Gregory J., Gainor, Justin, Engelman, Jeffrey A., Shapiro, Geoffrey I., Costa, Daniel B., Ou, Sai-Hong I., Butaney, Mohit, Salgia, Ravi, Maki, Robert G., Varella-Garcia, Marileila, Doebele, Robert C., Bang, Yung-Jue, Kulig, Kimary, Selaru, Paulina, Tang, Yiyun, Wilner, Keith D., Kwak, Eunice L., Clark, Jeffrey W., Iafrate, A. John, Camidge, D. Ross (2011) Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. The Lancet Oncology, 12 (11). pp. 1004-1012. ISSN 1470-2045

Shimizu, K., Birnbaum, D., Ruley, M. A., Fasano, O., Suard, Y., Edlund, L., Taparowsky, E., Goldfarb, M., Wigler, M. H. (1983) Structure of the Ki-Ras Gene of the Human-Lung Carcinoma Cell-Line Calu-1. Nature, 304 (5926). pp. 497-500. ISSN 0028-0836

Sordella, R. (2012) Talk from Raffaella Sordella at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)

Stahlhut, C., Slack, F. J. (2015) Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation. Cell Cycle, 14 (13). pp. 2171-80. ISSN 1551-4005 (Electronic)1551-4005 (Linking)

W

Wang, S. E., Narasanna, A., Perez-Torres, M., Xiang, B., Wu, F. Y., Yang, S., Carpenter, G., Gazdar, A. F., Muthuswamy, S. K., Arteaga, C. L. (2006) HER2 kinase domain mutation results in constitutive phosphorylation and activation of HER2 and EGFR and resistance to EGFR tyrosine kinase inhibitors. Cancer Cell, 10 (1). pp. 25-38. ISSN 15356108

Y

Yao, Z., Fenoglio, S., Gao, D. C., Camiolo, M., Stiles, B., Lindsted, T., Schlederer, M., Johns, C., Altorki, N., Mittal, V., Kenner, L., Sordella, R. (2010) TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proceedings of the National Academy of Sciences of the United States of America, 107 (35). pp. 15535-40. ISSN 0027-8424

Yu, J. R., Tai, Y., Jin, Y., Hammell, M. C., Wilkinson, J. E., Roe, J. S., Vakoc, C. R., Van Aelst, L. (2015) TGF-beta/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis. Genes Dev, 29 (3). pp. 250-61. ISSN 0890-9369

This list was generated on Wed Oct 18 16:20:59 2017 EDT.
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