Items where Subject is "diseases & disorders > cancer > cancer types > leukemia"

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Number of items at this level: 84.

A

Albers, C., Illert, A. L., Miething, C., Leischner, H., Thiede, M., Peschel, C., Duyster, J. (2011) An RNAi-based system for loss-of-function analysis identifies Raf1 as a crucial mediator of BCR-ABL - Driven leukemogenesis. Blood, 118 (8). pp. 2200-2210. ISSN 00064971 (ISSN)

B

Berman, E., Girotra, M., Cheng, C., Chanel, S., Maki, R., Shelat, M., Strauss, H. W., Fleisher, M., Heller, G., Farooki, A. (2013) Effect of long term imatinib on bone in adults with chronic myelogenous leukemia and gastrointestinal stromal tumors. Leuk Res, 37 (7). pp. 790-4. ISSN 1873-5835 (Electronic)0145-2126 (Linking)

Bhagwat, A. S., Roe, J. S., Mok, B. A., Vakoc, C. R. (2016) BET bromodomain inhibitors antagonize Brd4-Mediator complexes to undermine the acute myeloid leukemia cell state. Cancer Research, 76 (2). ISSN 0008-5472

Blobel, G. A., Kadauke, S., Wang, E., Lau, A. W., Zuber, J., Chou, M. M., Vakoc, C. R. (2009) A Reconfigured Pattern of MLL Occupancy within Mitotic Chromatin Promotes Rapid Transcriptional Reactivation Following Mitotic Exit. Molecular Cell, 36 (6). pp. 970-983.

Bots, M., Verbrugge, I., Martin, B. P., Salmon, J. M., Ghisi, M., Baker, A., Stanley, K., Shortt, J., Ossenkoppele, G. J., Zuber, J., Rappaport, A. R., Atadja, P., Lowe, S. W., Johnstone, R. W. (2014) Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors. Blood, 123 (9). pp. 1341-52. ISSN 0006-4971

C

Carpino, N., Wisniewski, D., Strife, A., Marshak, D., Kobayashi, R., Stillman, B., Clarkson, B. (1997) p62(dok): a constitutively tyrosine-phosphorylated, GAP-associated protein in chronic myelogenous leukemia progenitor cells. Cell, 88 (2). pp. 197-204. ISSN 0092-8674 (Print)

Chen, C., Liu, Y., Rappaport, A. R., Kitzing, T., Schultz, N., Zhao, Z., Shroff, A. S., Dickins, R. A., Vakoc, C. R., Bradner, J. E., Stock, W., Lebeau, M. M., Shannon, K. M., Kogan, S., Zuber, J., Lowe, S. W. (2014) MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia. Cancer Cell, 25 (5). pp. 652-665. ISSN 1878-3686 (Electronic)1535-6108 (Linking)

D

Delas Vivas, M.J. (2017) Role of long noncoding RNAs in hematopoiesis. PhD thesis, Cold Spring Harbor Laboratory.

F

Fanta, S., Sonnenberg, M., Skorta, I., Duyster, J., Miething, C., Aulitzky, W. E., van der Kuip, H. (2008) Pharmacological inhibition of c-Abl compromises genetic stability and DNA repair in Bcr-Abl-negative cells. Oncogene, 27 (31). pp. 4380-4384. ISSN 0950-9232

Fielding, A., Machin, S. J., Goldstone, A. H., Solomon, E., Gann, A. (1994) Acute promyelocytic leukaemia. The Lancet, 344 (8937). pp. 1615-1618. ISSN 0140-6736

G

Glaser, S. P., Lee, E. F., Trounson, E., Bouillet, P., Wei, A., Fairlie, W. D., Izon, D. J., Zuber, J., Rappaport, A. R., Herold, M. J., Alexander, W. S., Lowe, S. W., Robb, L., Strasser, A. (2012) Anti-apoptotic mcl-1 is essential for the development and sustained growth of acute myeloid leukemia. Genes and Development, 26 (2). pp. 120-125. ISSN 08909369 (ISSN)

Gordon, J. K., Magid, S. K., Maki, R. G., Fleisher, M., Berman, E. (2010) Elevations of creatine kinase in patients treated with imatinib mesylate (Gleevec). Leuk Res, 34 (6). pp. 827-9. ISSN 1873-5835 (Electronic)0145-2126 (Linking)

Grubor, V., Krasnitz, A., Troge, J. E., Meth, J. L., Lakshmi, B., Kendall, J. T., Yamrom, B., Alex, G., Pai, D., Navin, N. E., Hufnagel, L. A., Lee, Y. H., Cook, K., Allen, S. L., Rai, K. R., Damle, R. N., Calissano, C., Chiorazzi, N., Wigler, M. H., Esposito, D. (2009) Novel genomic alterations and clonal evolution in chronic lymphocytic leukemia revealed by representational oligonucleotide microarray analysis (ROMA). Blood, 113 (6). pp. 1294-1303. ISSN 0006-4971

Grubor, V. D., Troge, J. E., Meth, J. L., Lakshmi, B., Yamron, B., Hufnagel, L. A., Lee, Y. H., Kendall, J. T., Pai, D., Lee, A., Gregersen, P., Yancopoulos, S., Allen, S., Rai, K. R., Chiorazzi, N., Wigler, M. H., Esposito, D. (2006) Genome Analysis of CLL by Representational Oligonucleotide Microarray Analysis (ROMA). ASH Annual Meeting Abstracts, 108 (11). p. 2085.

H

Hein, N., Bywater, M. J., Stanley, K., Verbrugge, I., Cullinane, C., Baker, A., Zuber, H., Rappaport, A., Drygin, D., Huser, N., Bliesath, J., Ryckman, D. M., Rice, W. G., Lowe, S. W., Johnstone, R. W., Pearson, R. B., McArthur, G. A., Hannan, R. D. (2011) Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias. Blood, 118 (21). p. 673. ISSN 0006-4971

Herrmann, H., Blatt, K., Shi, J., Gleixner, K. V., Cerny-Reiterer, S., Mullauer, L., Vakoc, C. R., Sperr, W. R., Horny, H. P., Bradner, J. E., Zuber, J., Valent, P. (2012) Small-molecule inhibition of BRD4 as a new potent approach to eliminate leukemic stem- and progenitor cells in acute myeloid leukemia AML. Oncotarget, 3 (12). pp. 1588-99. ISSN 1949-2553

Herrmann, H., Blatt, K., Shi, J. W., Rappaport, A. R., Gleixner, K. V., Cerny-Reiterer, S., Peter, B., Wang, E., Sperr, W. R., Bradner, J. E., Lowe, S. W., Vakoc, C. R., Zuber, J., Valent, P. (2011) Small-Molecule Inhibition of BRD4 Is a Novel Promising Approach to Therapeutically Target Leukemia Stem Cells in AML. Blood, 118 (21). p. 1487. ISSN 0006-4971

Hohmann, A. F. (2016) Function and Inhibition of BRD9 in Acute Myeloid Leukemia Cells. PhD thesis, Cold Spring Harbor Laboratory.

J

Jones, L., Sevcikova, S., Phan, V., Jain, S., Shieh, A., Dubansky, J., Li, M., Maunakea, M. L., Zhu, G., Tennant, T. R., Lowe, S. W., Le Beau, M. M., Kogan, S. C. (2008) Myc Drives Chromosomal Gain in Acute Myeloid Leukemia. Blood, 112 (11). p. 294. ISSN 0006-4971

Jones, L., Wei, G., Sevcikova, S., Phan, V., Jain, S., Shieh, A., Wong, J. C., Li, M., Dubansky, J., Maunakea, M. L., Ochoa, R., Zhu, G., Tennant, T. R., Shannon, K. M., Lowe, S. W., Le Beau, M. M., Kogan, S. C. (2010) Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia. J Exp Med, 207 (12). pp. 2581-94. ISSN 0022-1007

K

King, Bryan, Trimarchi, Thomas, Reavie, Linsey, Xu, Luyao, Mullenders, Jasper, Ntziachristos, Panagiotis, Aranda-Orgilles, Beatriz, Perez-Garcia, Arianne, Shi, Junwei, Vakoc, Christopher, Sandy, Peter, Shen, Steven S, Ferrando, Adolfo, Aifantis, Iannis (2013) The Ubiquitin Ligase FBXW7 Modulates Leukemia-Initiating Cell Activity by Regulating MYC Stability. Cell, 153 (7). pp. 1552-1566. ISSN 0092-8674

M

MacDowell, E. Carleton (1935) Maternal influence in the inheritance of spontaneous mouse leukemia (Abstract). The American Naturalist, 69 (720). p. 68.

MacDowell, E. Carleton, Richter, Maurice N. (1930) Genetic control of susceptibility to the inoculated mouse leukemia of lines I and L (Abstract). The Anatomical Record, 47 (3). p. 387.

MacDowell, Edwin Carleton (1935) Maternal influence upon longevity and upon the incidence of leukemia in mice (Abstract). Science, 81 (2105). p. 418.

MacDowell, Edwin Carleton, Potter, James S., Victor, Joseph (1935) Leukemia studies. Documentation. Carnegie Institution of Washington, Washington, D.C..

MacDowell, Edwin Carleton, Richter, Maurice N. (1931) Genetic and histological studies on mouse leukemia. Science, 74 (1928). pp. 605-606.

MacDowell, Edwin Carleton, Richter, Maurice N. (1935) Mouse leukemia. IX. The rôle of heredity in spontaneous cases. Archives of Pathology, 20. pp. 709-724.

MacDowell, Edwin Carleton, Richter, Maurice N. (1930) Studies on mouse leukemia. II. Hereditary susceptibility to inoculated leukemia. The Journal of Cancer Research, 14 (3). pp. 434-439.

MacDowell, Edwin Carleton, Richter, Maurice N. (1931) Studies on mouse leukemia. IV: Specificity of susceptibility to different lines of inoculated leukemia. Proceedings of the Society for Experimental Biology and Medicine, 28 (9). pp. 1012-1013.

MacDowell, Edwin Carleton, Taylor, Martha J., Potter, James S. (1934) Immunization of mice naturally susceptible to a transplantable leukemia. Proceedings of the Society for Experimental Biology and Medicine, 32. pp. 84-86.

MacDowell, Edwin Carleton, Taylor, Martha J., Potter, James S. (1935) The dependence of protection against a transplantable mouse leukemia upon the genetic constitution of the immunizing tissue. Proceedings of the National Academy of Sciences, 21 (8). pp. 507-508.

Matthews, G. M., Cluse, L., Wang, E., Roth, M., Vakoc, C., Miao, W. Y., Rusche, J., Zuber, J., Johnstone, R. W. (2014) RNAi-mediated depletion of histone deacetylases highlights the potential for isoform-specific inhibitors in B-cell lymphoma and acute myeloid leukemia. Cancer Research, 74 (19). ISSN 0008-5472

Mavrakis, K. J., Wolfe, A. L., Oricchio, E., Palomero, T., de Keersmaecker, K., McJunkin, K., Zuber, J., James, T., Chang, K., Khan, A. A., Leslie, C. S., Parker, J. S., Paddison, P. J., Tam, W., Ferrando, A., Wendel, H. G. (2010) Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia. Nature Cell Biology, 12 (4). 372-U159. ISSN 1465-7392

Mazurek, A., Park, Y., Miething, C., Wilkinson, J. E., Gillis, J., Lowe, S. W, Vakoc, C. R, Stillman, B. (2014) Acquired Dependence of Acute Myeloid Leukemia on the DEAD-Box RNA Helicase DDX5. Cell Reports, 7 (6). pp. 1887-1899. ISSN 2211-1247

Meacham, C. E., Lawton, L. N., Soto-Feliciano, Y. M., Pritchard, J. R., Joughin, B. A., Ehrenberger, T., Fenouille, N., Zuber, J., Williams, R. T., Young, R. A., Hemann, M. T. (2015) A genome-scale in vivo loss-of-function screen identifies Phf6 as a lineage-specific regulator of leukemia cell growth. Genes & Development, 29 (5). pp. 483-8. ISSN 0890-9369

Miething, C., Scuoppo, C., Bosbach, B., Appelmann, I., Nakitandwe, J., Ma, J., Wu, G., Lintault, L., Auer, M., Premsrirut, P. K., Teruya-Feldstein, J., Hicks, J., Benveniste, H., Speicher, M. R., Downing, J. R., Lowe, S. W. (2014) PTEN action in leukaemia dictated by the tissue microenvironment. Nature, 510 (7505). p. 402. ISSN 0028-0836

N

Niki, M., Di Cristofano, A., Zhao, M., Honda, H., Hirai, H., Van Aelst, L., Cordon-Cardo, C., Pandolfi, P. P. (2004) Role of Dok-1 and Dok-2 in leukemia suppression. J Exp Med, 200 (12). pp. 1689-95.

Niki, M., Di Cristofano, A., Zhao, M., Karnell, F. G., Clarkson, B., Pear, W. S., Van Aelst, L., Pandolfi, P. P. (2000) Role of p65(dok) in leukemogenesis by p210(bcr-abl). Blood, 96 (11). 510A-510A. ISSN 0006-4971

Niki, M., Di Cristofano, A., Zhao, M. M., Hirai, H., Van Aelst, L., Cordon-Cardo, C., Pandolfi, P. P. (2004) Critical role of Dok-1 and Dok-2 in leukemia suppression. Blood, 104 (11). 807A-807A. ISSN 0006-4971

Niki, M., Di Cristofano, A., Zhao, M. M., Honda, H., Hirai, H., Van Aelst, L., Cordon-Cardo, C., Pandolfi, P. P. (2004) Role of Dok-1 and Dok-2 in leukemia suppression. Journal of Experimental Medicine, 200 (12). pp. 1689-1695. ISSN 0022-1007

O

Okuda, T., Valentine, M. B., Shurtleff, S. A., Hulshof, M. G., Komuro, H., Raimondi, S. C., Pui, C. H., Beach, D., Sherr, C. J., Look, A. T., Downing, J. R. (1994) Frequent Deletion of Ink4a/Mts1 in Pediatric Acute Lymphoblastic-Leukemia. Blood, 84 (10). A298-A298. ISSN 0006-4971

P

Pardee, T., Zuber, J., Lowe, S. W. (2009) The Flt3 ITD Accelerates An Already Established Myeloid Leukemia and Alters Chemotherapy Response In Vitro and In Vivo in a p53 Dependent Manner. Blood, 114 (22). p. 685. ISSN 0006-4971

Pardee, T. S., Zuber, J., Lowe, S. W. (2009) Effects of the Flt3 ITD on response to chemotherapy in a murine model of acute myeloid leukemia. Journal of Clinical Oncology, 27 (15). p. 7060. ISSN 0732-183X

Pardee, T. S., Zuber, J., Lowe, S. W. (2011) Flt3-ITD alters chemotherapy response in vitro and in vivo in a p53-dependent manner. Exp Hematol, 39 (4). 473-485 e4. ISSN 1873-2399 (Electronic)0301-472X (Linking)

Potter, James S., Findley, M. D. (1935) Histological observations on resistance to transplantable leukemia in immunized mice. Carnegie Institution of Washington News Service Bulletin, 32. pp. 1338-1340.

Potter, James S., Richter, Maurice N. (1932) Studies on mouse leukemia. VI. The predominating cell type in Line I. Proceedings of the National Academy of Sciences, 18 (4). pp. 298-303.

Potter, James S., Richter, Maurice N. (1933) Studies on mouse leukemia. VIII. Continuity of cell lineage in transmission lines of lymphatic leukemia. Archives of Pathology & Laboratory Medicine, 15. pp. 198-212.

Potter, James S., Richter, Maurice N. (1932) The origin of infiltrating cells in transmissible lymphatic leukemia of mice. Archives of Pathology & Laboratory Medicine, 14 (2).

R

Ramani, R., Megason, G., Schallheim, J., Karlson, C., Vijayakumar, V., Vijayakumar, S., Hicks, C. (2017) Integrative Analysis of MicroRNA-Mediated Gene Signatures and Pathways Modulating White Blood Cell Count in Childhood Acute Lymphoblastic Leukemia. Biomarker Insights, 12. p. 1177271917702895. ISSN 1177-2719

Rappaport, A. R. (2011) Dissecting tumor suppressor and tumor maintenance genes in poor prognosis AML. PhD thesis, Cold Spring Harbor Laboratory.

Rathert, P., Roth, M., Neumann, T., Muerdter, F., Roe, J. S., Muhar, M., Deswal, S., Cerny-Reiterer, S., Peter, B., Jude, J., Hoffmann, T., Boryn, L. M., Axelsson, E., Schweifer, N., Tontsch-Grunt, U., Dow, L. E., Gianni, D., Pearson, M., Valent, P., Stark, A., Kraut, N., Vakoc, C. R., Zuber, J. (2015) Transcriptional plasticity promotes primary and acquired resistance to BET inhibition. Nature, 525. pp. 543-547. ISSN 1476-4687 (Electronic)0028-0836 (Linking)

Richter, Maurice N., MacDowell, Edwin Carleton (1935) Experiments with mammalian leukemia. Physiological Reviews, 15 (4). pp. 509-524.

Richter, Maurice N., MacDowell, Edwin Carleton (1930) Studies on leukemia in mice. I: The experimental transmission of leukemia. The Journal of Experimental Medicine, 51 (4). pp. 659-673.

Richter, Maurice N., MacDowell, Edwin Carleton (1930) Studies on mouse leukemia. III. A comparison of four lines of leukemia transmitted by inoculation. The Journal of Experimental Medicine, 52 (6). pp. 823-833.

Richter, Maurice N., MacDowell, Edwin Carleton (1933) Studies on mouse leukemia. VII. The relation of cell death to the potency of inoculated cell suspensions. The Journal of Experimental Medicine, 57 (1). pp. 1-20.

Roe, J. S., Vakoc, C. R. (2014) C/EBPalpha: critical at the origin of leukemic transformation. Journal of Experimental Medicine, 211 (1). pp. 1-4. ISSN 0022-1007

Roe, J. S., Vakoc, C. R. (2017) The Essential Transcriptional Function of BRD4 in Acute Myeloid Leukemia. Cold Spring Harb Symp Quant Biol. ISSN 0091-7451

Roe, Jae-Seok, Mercan, Fatih, Rivera, Keith, Pappin, Darryl J, Vakoc, Christopher R (2015) BET Bromodomain Inhibition Suppresses the Function of Hematopoietic Transcription Factors in Acute Myeloid Leukemia. Molecular Cell, 58 (6). pp. 1028-1036. ISSN 1097-2765

S

Shen, Chen, Ipsaro, Jonathan J, Shi, Junwei, Milazzo, Joseph P, Wang, Eric, Roe, Jae-Seok, Suzuki, Yutaka, Pappin, Darryl J, Joshua-Tor, Leemor, Vakoc, Christopher R (2015) NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler. Molecular Cell, 60 (6). pp. 847-859. ISSN 1097-2765

Shi, J., Wang, E., Zuber, J., Rappaport, A., Taylor, M., Johns, C., Lowe, S. W., Vakoc, C. R. (2013) The Polycomb complex PRC2 supports aberrant self-renewal in a mouse model of MLL-AF9;Nras(G12D) acute myeloid leukemia. Oncogene, 32 (7). pp. 930-938. ISSN 1476-5594 (Electronic)0950-9232 (Linking)

Shi, J., Whyte, W. A., Zepeda-Mendoza, C. J., Milazzo, J. P., Shen, C., Roe, J. S., Minder, J. L., Mercan, F., Wang, E., Eckersley-Maslin, M. A., Campbell, A. E., Kawaoka, S., Shareef, S., Zhu, Z., Kendall, J., Muhar, M., Haslinger, C., Yu, M., Roeder, R. G., Wigler, M. A., Blobel, G. A., Zuber, J., Spector, D. L., Young, R. A., Vakoc, C. R. (2013) Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation. Genes and Development, 27 (24). pp. 264-273. ISSN 08909369 (ISSN)

Somerville, Tim D D., Vakoc, Christopher R (2016) Modeling the Epigenetic Chain Reaction Downstream of DNMT3A(R882H). Cancer Cell, 30 (1). pp. 9-10. ISSN 1535-6108

Speck, N. A., Vakoc, C. R. (2010) PAF Is in the Cabal of MLL1-Interacting Proteins that Promote Leukemia. Cancer Cell, 17 (6). pp. 531-532.

Spector, M. S., Iossifov, I., Kritharis, A., He, C., Kolitz, J. E., Lowe, S. W., Allen, S. L. (2012) Mast-cell leukemia exome sequencing reveals a mutation in the IgE mast-cell receptor beta chain and KIT V654A. Leukemia, 26 (6). pp. 1422-1425. ISSN 0887-6924

Steger, D. J., Lefterova, M. I., Ying, L., Stonestrom, A. J., Schupp, M., Zhuo, D., Vakoc, A. L., Kim, J. E., Chen, J., Lazar, M. A., Blobel, G. A., Vakoc, C. R. (2008) DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Molecular and Cellular Biology, 28 (8). pp. 2825-2839. ISSN 02707306 (ISSN)

Svingen, P. A., Karp, J. E., Krajewski, S., Mesner, P. W., Gore, S. D., Burke, P. J., Reed, J. C., Lazebnik, Y. A., Kaufmann, S. H. (2000) Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia. Blood, 96 (12). pp. 3922-3931. ISSN 0006-4971

T

Tuveson, D., Rai, K. R. (2015) Augmenting NF-kappaB in poor-risk CLL: A general paradigm for other cancers? J Exp Med, 212 (6). pp. 830-1. ISSN 1540-9538 (Electronic)0022-1007 (Linking)

Tyagi, S., Chabes, A. L., Wysocka, J., Herr, W. (2007) E2F Activation of S Phase Promoters via Association with HCF-1 and the MLL Family of Histone H3K4 Methyltransferases. Molecular Cell, 27 (1). pp. 107-119. ISSN 1097-2765

V

Vakoc, C. R., Zuber, J., Lowe, S., Wang, E., Rappaport, A. R., Shi, J. W. (2010) An RNA1 Screen Reveals a Pattern of Addiction to Epigenetic Pathways That Distinguishes MLL AF9 Leukemia From Normal Hematopoietic Cells. Blood, 116 (21). p. 35. ISSN 0006-4971

Victor, Joseph, Potter, James S. (1933) Metabolic differences between two transmission lines of mouse leukemia. Proceedings of the Society for Experimental Biology and Medicine, 30. pp. 532-534.

Victor, Joseph, Wintersteiner, M. R. (1934) Studies in mouse leukemia. X. Metabolic differences between transmission lines of mouse lymphatic leukemia. The American Journal of Cancer , 22 (3). pp. 561-571.

W

Wang, E., Kawaoka, S., Roe, J. S., Shi, J., Hohmann, A. F., Xu, Y., Bhagwat, A. S., Suzuki, Y., Kinney, J. B., Vakoc, C. R. (2015) The transcriptional cofactor TRIM33 prevents apoptosis in B lymphoblastic leukemia by deactivating a single enhancer. Elife, 4. ISSN 2050-084X (Electronic)2050-084X (Linking)

Wedeh, G., Cerny-Reiterer, S., Hadzijusufovic, E., Herrmann, H., Blatt, K., Eisenwort, G., Hoermann, G., Sperr, W. R., Muellauer, L., Vakoc, C. R., Bradner, J. E., Horny, H., Zuber, J., Arock, M., Valent, P. (2014) The epigenetic reader brd4 serves as a novel marker and target in aggressive systemic mastocytosis and mast cell leukemia. Haematologica, 99. pp. 514-515. ISSN 0390-6078

Wendel, Hans-Guido, de Stanchina, Elisa, Cepero, Enriqué, Ray, Sagarika, Emig, Michael, Fridman, Jordan S., Veach, Darren R., Bornmann, William G., Clarkson, Bayard, McCombie, W. Richard, Kogan, Scott C., Hochhaus, Andreas, Lowe, Scott W. (2006) Loss of p53 impedes the antileukemic response to BCR-ABL inhibition. Proceedings of the National Academy of Sciences of the United States of America, 103 (19). pp. 7444-9. ISSN 0027-8424

Westfall, M., Spector, M. S., Gulrajani, M., Marimpietri, C., Kritharis, A., Fields, S. Z., Allen, S. L., Hawtin, R. (2013) Functional characterization of KIT and Fc epsilon R1 receptor mutations in Mast Cell Leukemia using Single Cell Network Profiling (SCNP). Cancer Research, 73 (8 (Sup). p. 3524. ISSN 0008-5472

Y

Yang, L. V., Wan, J., Ge, Y., Fu, Z., Kim, S. Y., Fujiwara, Y., Taub, J. W., Matherly, L. H., Eliason, J., Li, L. (2006) The GATA site-dependent hemogen promoter is transcriptionally regulated by GATA1 in hematopoietic and leukemia cells. Leukemia, 20 (3). pp. 417-425. ISSN 08876924

Yin, Bin, Diers, M. D., Rathe, S. K., Lowe, S. W., Largaespada, D. A. (2006) Genetic mechanisms of cytarabine resistance in leukemia: cell culture and mouse transplantation models. ASH Annual Meeting Abstracts, 108 (11). p. 4374. ISSN 0006-4971

Yin, Bin, Kogan, Scott C., Dickins, Ross A., Lowe, Scott W., Largaespada, David A. (2006) Trp53 loss during in vitro selection contributes to acquired Ara-C resistance in acute myeloid leukemia. Experimental Hematology, 34 (5). pp. 631-641. ISSN 0301472X

Yokoyama, A., Wang, Z., Wysocka, J., Sanyal, M., Aufiero, D. J., Kitabayashi, I., Herr, W., Cleary, M. L. (2004) Leukemia proto-oncoprotein MLL forms a SET1-like histone methyltransferase complex with menin to regulate Hox gene expression. Molecular and Cellular Biology, 24 (13). pp. 5639-5649. ISSN 0270-7306

Z

Zhao, Z., Chen, C. C., Rillahan, C. D., Shen, R., Kitzing, T., McNerney, M. E., Diaz-Flores, E., Zuber, J., Shannon, K., Le Beau, M. M., Spector, M. S., Kogan, S. C., Lowe, S. W. (2015) Cooperative loss of RAS feedback regulation drives myeloid leukemogenesis. Nature Genetics, 47. pp. 539-543. ISSN 1061-4036

Zhao, Z., Zuber, J., Diaz-Flores, E., Lintault, L., Kogan, S. C., Shannon, K., Lowe, S. W. (2010) p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal. Genes Dev, 24 (13). pp. 1389-1402. ISSN 1549-5477 (Electronic) 0890-9369 (Linking)

Zuber, J., Radtke, I., Pardee, T. S., Zhao, Z., Rappaport, A. R., Luo, W., McCurrach, M. E., Yang, M. M., Dolan, M. E., Kogan, S. C., Downing, J. R., Lowe, S. W. (2009) Mouse models of human AML accurately predict chemotherapy response. Genes Dev, 23 (7). pp. 877-89.

Zuber, J., Rappaport, A. R., Luo, W., Wang, E., Chen, C., Vaseva, A. V., Shi, J., Weissmueller, S., Fellman, C., Taylor, M. J., Weissenboeck, M., Graeber, T. G., Kogan, S. C., Vakoc, C. R., Lowe, S. W. (2011) An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes & Development, 25 (15). pp. 1628-1640. ISSN 0890-9369

Zuber, J., Shi, J., Wang, E., Rappaport, A. R., Herrmann, H., Sison, E. A., Magoon, D., Qi, J., Blatt, K., Wunderlich, M., Taylor, M. J., Johns, C., Chicas, A., Mulloy, J. C., Kogan, S. C., Brown, P., Valent, P., Bradner, J. E., Lowe, S. W., Vakoc, C. R. (2011) RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature, 478 (7370). pp. 524-528. ISSN 0028-0836

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