Items where Subject is "bioinformatics > genomics and proteomics > genetics & nucleic acid processing > protein structure, function, modification > protein types > GTPase"

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Number of items at this level: 48.

A

Andersen, L. B., Ballester, R., Marchuk, D. A., Chang, E., Gutmann, D. H., Saulino, A. M., Camonis, J., Wigler, M. H., Collins, F. S. (1993) A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity. Molecular and Cellular Biology, 13 (1). pp. 487-495. ISSN 0270-7306

B

Benitah, S. A., Valeron, P. F., Van Aelst, L., Marshall, C. J., Lacal, J. C. (2004) Rho GTPases in human cancer: an unresolved link to upstream and downstream transcriptional regulation. Biochimica Et Biophysica Acta-Reviews on Cancer, 1705 (2). pp. 121-132. ISSN 0304-419X

Boettner, B., Govek, E. E., Cross, J., Van Aelst, L. (2000) The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin. Proceedings of the National Academy of Sciences of the United States of America, 97 (16). pp. 9064-9069. ISSN 0027-8424

Boettner, B., Harjes, P., Gaul, U., Van Aelst, L. (2001) Functional interaction of the small Rap GTPase and the junctional Canoe protein during embryonic dorsal closure in Drosophila melanogaster. Molecular Biology of the Cell, 12. 370A-370A. ISSN 1059-1524

Boettner, B., Harjes, P., Ishimaru, S., Heke, M., Fan, H. Q., Qin, Y., Van Aelst, L., Gaul, U. (2003) The AF-6 homolog Canoe acts as a Rap1 effector during dorsal closure of the Drosophila embryo. Genetics, 165 (1). pp. 159-169. ISSN 0016-6731

Boettner, B., Van Aelst, L. (2013) Introduction to the ECR special issue on the roles of small GTPases. Experimental Cell Research, 319 (15). p. 2309. ISSN 00144827

Boettner, B., Van Aelst, L. (2007) The Rap GTPase Activator Drosophila PDZ-GEF Regulates Cell Shape in Epithelial Migration and Morphogenesis. Mol Cell Biol, 27 (22). pp. 7966-7980. ISSN 0270-7306 (Print)

Boettner, B., Van Aelst, L. (2002) The role of Rho GTPases in disease development. Gene, 286 (2). pp. 155-74. ISSN 0378-1119 (Print)

Boyer, M. J., Gutmann, D. H., Collins, F. S., Bar-Sagi, D. (1994) Crosslinking of the surface immunoglobulin receptor in B lymphocytes induces a redistribution of neurofibromin but not p120-GAP. Oncogene, 9 (2). pp. 349-57. ISSN 0950-9232 (Print)

Bui, H. T., Shaw, J. M. (2013) Dynamin assembly strategies and adaptor proteins in mitochondrial fission. Current Biology, 23 (19). R891-R899. ISSN 09609822 (ISSN)

C

Chang, E. C., Barr, M., Wang, Y., Jung, V., Xu, H. P., Wigler, M. H. (1994) Cooperative interaction of S. pombe proteins required for mating and morphogenesis. Cell, 79 (1). pp. 131-41. ISSN 0092-8674 (Print)

Chen, R. A., Michaeli, T., Van Aelst, L., Ballester, R. (2000) A role for the noncatalytic N terminus in the function of Cdc25, a Saccharomyces cerevisiae Ras-guanine nucleotide exchange factor. Genetics, 154 (4). pp. 1473-1484. ISSN 0016-6731

G

Gale, N. W., Kaplan, S., Lowenstein, E. J., Schlessinger, J., Bar-Sagi, D. (1993) Grb2 mediates the EGF-dependent activation of guanine nucleotide exchange on Ras. Nature, 363 (6424). pp. 88-92. ISSN 0028-0836 (Print)

Govek, E. E., Newey, S. E., Akerman, C. J., Cross, J. R., Van der Veken, L., Van Aelst, L. (2004) The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis. Nat Neurosci, 7 (4). pp. 364-72. ISSN 1097-6256 (Print)

Govek, E. E., Newey, S. E., Van Aelst, L. (2005) The role of the Rho GTPases in neuronal development. Genes Dev, 19 (1). pp. 1-49. ISSN 0890-9369 (Print)

Gumienny, T. L., Brugnera, E., Tosello-Trampont, A. C., Kinchen, J. M., Haney, L. B., Nishiwaki, K., Walk, S. F., Nemergut, M. E., Macara, I. G., Francis, R., Schedl, T., Qin, Y., Van Aelst, L., Hengartner, M. O., Ravichandran, K. S. (2001) CED-12/ELMO, a novel member of the crkII/dock180/rac pathway, is required for phagocytosis and cell migration. Cell, 107 (1). pp. 27-41. ISSN 0092-8674

Guo, H. F., Tong, J. Y., Hannan, F., Luo, L., Zhong, Y. (2000) A neurofibromatosis-1-regulated pathway is required for learning in Drosophila. Nature, 403 (6772). pp. 895-898. ISSN 0028-0836

Gutmann, D. H., Boguski, M., Marchuk, D., Wigler, M. H., Collins, F. S., Ballester, R. (1993) Analysis of the neurofibromatosis type-1 (NF1) GAP-related domain by site-directed mutagenesis. Oncogene, 8 (3). pp. 761-769. ISSN 0950-9232

J

Jiang, W., Sordella, R., Chen, G. C., Hakre, S., Roy, A. L., Settleman, J. (2005) An FF domain-dependent protein interaction mediates a signaling pathway for growth factor-induced gene expression. Molecular Cell, 17 (1). pp. 23-35. ISSN 1097-2765

K

Kashige, N., Carpino, N., Kobayashi, R. (2000) Tyrosine phosphorylation of p62(dok) by p210(bcr-abl) inhibits RasGAP activity. Proceedings of the National Academy of Sciences of the United States of America, 97 (5). pp. 2093-2098. ISSN 0027-8424

Kimmelman, A. C., Hezel, A. F., Aguirre, A. J., Zheng, H. W., Paik, J. H., Ying, H. Q., Chu, G. C., Zhang, J. X., Sahin, E., Yeo, G. M., Ponugoti, A., Nabioullin, R., Deroo, S., Yang, S. D., Wang, X. X., McGrath, J. P., Protopopova, M., Ivanova, E., Zhang, J. H., Feng, B., Tsao, M. S., Redston, M., Protopopov, A., Xiao, Y. H., Futreal, P. A., Hahn, W. C., Klimstra, D. S., Chin, L., DePinho, R. A. (2008) Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer. Proceedings of the National Academy of Sciences of the United States of America, 105 (49). pp. 19372-19377. ISSN 0027-8424

Kontaridis, M. I., Eminaga, S., Fornaro, M., Zito, C. I., Sordella, R., Settleman, J., Bennett, A. M. (2004) SHP-2 positively regulates myogenesis by coupling to the Rho GTPase signaling pathway. Molecular and Cellular Biology, 24 (12). pp. 5340-52. ISSN 0270-7306

L

Li, Z., Aizenman, C. D., Cline, H. T. (2002) Regulation of rho GTPases by crosstalk and neuronal activity in vivo. Neuron, 33 (5). pp. 741-750. ISSN 0896-6273

Li, Z., Van Aelst, L., Cline, H. T. (2000) Rho GTPases regulate distinct aspects of dendritic arbor growth in Xenopus central neurons in vivo. Nature Neuroscience, 3 (3). pp. 217-225. ISSN 1097-6256

M

Matheson, S. F., Hu, K. Q., Brouns, M. R., Sordella, R., VanderHeide, J. D., Settleman, J. (2006) Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development. Developmental Neuroscience, 28 (6). pp. 538-50. ISSN 0378-5866 (Print)

Matsumoto, T., Beach, D. (1991) Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase. Cell, 66 (2). pp. 347-60. ISSN 0092-8674 (Print)0092-8674 (Linking)

Matsumoto, T., Beach, D. (1991) Spi1 GTPase interacts with RCC1 to maintain interdependency of cell cycle events. Princess Takamatsu Symp, 22. pp. 145-52.

Matsumoto, T., Beach, D. (1991) The spil GTPase interacts with RCCl in cell cycle dependency. Cold Spring Harb Symp Quant Biol, 56. pp. 385-98. ISSN 0091-7451 (Print)0091-7451 (Linking)

N

Neuwald, A. F., Kannan, N., Poleksic, A., Hata, N., Liu, J. S. (2003) Ran's C-terminal, basic patch, and nucleotide exchange mechanisms in light of a canonical structure for Rab, Rho, Ras, and Ran GTPases. Genome Research, 13 (4). pp. 673-692. ISSN 1088-9051

Newey, S. E., Velamoor, V., Govek, E.-E., Van Aelst, L. (2005) Rho GTPases, dendritic structure, and mental retardation. J Neurobiol, 64 (1). pp. 58-74. ISSN 0022-3034 (Print)

P

Pawlak, G., Helfman, D. M. (2002) MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway. Journal of Biological Chemistry, 277 (30). pp. 26927-26933. ISSN 0021-9258

Pawlak, G., Helfman, D. M. (2002) Post-transcriptional down-regulation of ROCKI/Rho-kinase through an MEK-dependent pathway leads to cytoskeleton disruption in Ras-transformed fibroblasts. Molecular Biology of the Cell, 13 (1). pp. 336-347. ISSN 1059-1524

Pei, L., Peng, Y., Yang, Y., Ling, X. B., Van Eyndhoven, W. G., Nguyen, K. C., Rubin, M., Hoey, T., Powers, S., Li, J. (2002) PRC17, a novel oncogene encoding a Rab GTPase-activating protein, is amplified in prostate cancer. Cancer Res, 62 (19). pp. 5420-4. ISSN 0008-5472 (Print)0008-5472

Powers, S. (1995) Cdc25p, Ira1p, and Ira2p. In: Guidebook to the small GTPases. Oxford University Press. ISBN 9780198599449

S

Schmitz, A. A. P., Govek, E. E., Bottner, B., Van Aelst, L. (2000) Rho GTPases: Signaling, migration, and invasion. Experimental Cell Research, 261 (1). pp. 1-12. ISSN 0014-4827

Silva, A. J., Frankland, P. W., Marowitz, Z., Friedman, E., Laszlo, G. S., Cioffi, D., Jacks, T., Bourtchuladze, R. (1997) A mouse model for the learning and memory deficits associated with neurofibromatosis type I. Nature Genetics, 15 (3). pp. 281-4. ISSN 1061-4036 (Print)

Sin, W. C., Haas, K., Ruthazer, E. S., Cline, H. T. (2002) Dendrite growth increased by visual activity requires NMDA receptor and Rho GTPases. Nature, 419 (6906). pp. 475-480. ISSN 0028-0836

Soderling, S. H., Van Aelst, L. (2014) Principles driving the spatial organization of Rho GTPase signaling at synapses. In: Ras Superfamily Small G Proteins: Biology and Mechanisms 1: General Features, Signaling. Springer, pp. 395-419. ISBN 978-370911806-13709118050978-370911805-4S

Sordella, R., Classon, M., Hu, K. Q., Matheson, S. F., Brouns, M. R., Fine, B., Zhang, L., Takami, H., Yamada, Y., Settleman, J. (2002) Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development. Developmental Cell, 2 (5). pp. 553-65. ISSN 1534-5807

Sordella, R., Jiang, W., Chen, G. C., Curto, M., Settleman, J. (2003) Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis. Cell, 113 (2). pp. 147-58. ISSN 0092-8674 (Print)

Sordella, R., Van Aelst, L. (2008) Dialogue between RhoA/ROCK and Members of the Par Complex in Cell Polarity. Developmental Cell, 14 (2). pp. 150-2. ISSN 1534-5807

V

Van Aelst, L. (2011) Talk from Linda Van Aelst at the Cold Spring Harbor Laboratory In-House Symposium (2011). [Video] (Unpublished)

Van Aelst, L., Cline, H. T. (2004) Rho GTPases and activity-dependent dendrite development. Curr Opin Neurobiol, 14 (3). pp. 297-304. ISSN 0959-4388 (Print)

Van Aelst, L., Symons, M. (2002) Role of Rho family GTPases in epithelial morphogenesis. Genes & Development, 16 (9). pp. 1032-1054. ISSN 0890-9369

W

Watabe-Uchida, M., Govek, E. E., Van Aelst, L. (2006) Regulators of Rho GTPases in neuronal development. J Neurosci, 26 (42). pp. 10633-5. ISSN 1529-2401 (Electronic)

Y

Yajnik, V., Paulding, C., Sordella, R., McClatchey, A. I., Saito, M., Wahrer, D. C., Reynolds, P., Bell, D. W., Lake, R., van den Heuvel, S., Settleman, J., Haber, D. A. (2003) DOCK4, a GTPase activator, is disrupted during tumorigenesis. Cell, 112 (5). pp. 673-84. ISSN 0092-8674 (Print)

Yasuda, Ryohei, Harvey, Christopher D., Zhong, Haining, Sobczyk, Aleksander, Van Aelst, Linda, Svoboda, Karel (2006) Supersensitive Ras activation in dendrites and spines revealed by two-photon fluorescence lifetime imaging. Nature Neuroscience, 9 (2). pp. 283-291. ISSN 10976256

Z

Zhu, J. J., Qin, Y., Zhao, M. M., Van Aelst, L., Malinow, R. (2002) Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell, 110 (4). pp. 443-455. ISSN 0092-8674

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