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Song, Dongyan, Cen, Yuxin, Qian, Zhe, Wu, Xiaoli S, Rivera, Keith, Wee, Tse-Luen, Demerdash, Osama E, Chang, Kenneth, Pappin, Darryl, Vakoc, Christopher R, Tonks, Nicholas K (November 2024) PTPN23-dependent ESCRT machinery functions as a cell death checkpoint. Nature Communications, 15 (1). p. 10364. ISSN 2041-1723 (Public Dataset)

Zubiete-Franco, Imanol, Tonks, Nicholas K (September 2024) Famotidine increases cellular phospho-tyrosine levels. Biochemical and Biophysical Research Communications, 734. p. 150763. ISSN 0006-291X

Qian, Zhe, Song, Dongyan, Ipsaro, Jonathan J, Bautista, Carmelita, Joshua-Tor, Leemor, Yeh, Johannes T-H, Tonks, Nicholas K (September 2023) Manipulating PTPRD function with ectodomain antibodies. Genes and Development. ISSN 0890-9369

Tonks, Nicholas K (April 2023) Protein Tyrosine Phosphatases: Mighty oaks from little acorns grow. IUBMB Life, 75 (4). pp. 337-352. ISSN 1521-6543

Bonham, ChristopherA, Mandati, Vinay, Singh, RakeshK, Pappin, DarrylJ, Tonks, NicholasK (March 2023) Coupling substrate-trapping with proximity-labeling to identify protein tyrosine phosphatase PTP1B signaling networks. Journal of Biological Chemistry. p. 104582. ISSN 0021-9258

Song, Dongyan, Adrover, Jose M, Felice, Christy, Christensen, Lisa N, He, Xue-Yan, Merrill, Joseph R, Wilkinson, John E, Janowitz, Tobias, Lyons, Scott K, Egeblad, Mikala, Tonks, Nicholas K (July 2022) PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils. JCI Insight, 7 (14). e158199. ISSN 2379-3708

Wiede, Florian, Lu, Kun-Hui, Du, Xin, Zeissig, Mara N, Xu, Rachel, Goh, Pei Kee, Xirouchaki, Chrysovalantou E, Hogarth, Samuel J, Greatorex, Spencer, Sek, Kevin, Daly, Roger J, Beavis, Paul A, Darcy, Phillip K, Tonks, Nicholas K, Tiganis, Tony (November 2021) PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity. Cancer Discovery. ISSN 2159-8274

Ge, Eva J, Bush, Ashley I, Casini, Angela, Cobine, Paul A, Cross, Justin R, DeNicola, Gina M, Dou, Q Ping, Franz, Katherine J, Gohil, Vishal M, Gupta, Sanjeev, Kaler, Stephen G, Lutsenko, Svetlana, Mittal, Vivek, Petris, Michael J, Polishchuk, Roman, Ralle, Martina, Schilsky, Michael L, Tonks, Nicholas K, Vahdat, Linda T, Van Aelst, Linda, Xi, Dan, Yuan, Peng, Brady, Donita C, Chang, Christopher J (November 2021) Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews Cancer. ISSN 1474-175X

Bencze, G., Bencze, S., Rivera, K. D., Watson, J. D., Orfi, L., Tonks, N. K., Pappin, D. J. (August 2020) Mito-oncology agent: fermented extract suppresses the Warburg effect, restores oxidative mitochondrial activity, and inhibits in vivo tumor growth. Sci Rep, 10 (1). p. 14174. ISSN 2045-2322

Fu, P., Ramchandran, R., Shaaya, M., Huang, L., Ebenezer, D.L., Jiang, Y., Komarova, Y., Vogel, S.M., Malik, A.B., Minshall, R.D., Du, G., Tonks, N. K., Natarajan, V. (April 2020) Phospholipase D2 Restores Endothelial Barrier Function by Promoting PTPN14-mediated VE-cadherin Dephosphorylation. Journal of Biological Chemistry, 295 (22). pp. 7669-7685. ISSN 0021-9258

Londhe, A. D., Bergeron, A., Curley, S. M., Zhang, F., Rivera, K. D., Kannan, A., Coulis, G., Rizvi, S. H. M., Kim, S. J., Pappin, D. J., Tonks, N. K., Linhardt, R. J., Boivin, B. (December 2019) Regulation of PTP1B activation through disruption of redox-complex formation. Nat Chem Biol, 16 (2). pp. 122-125. ISSN 1552-4450

Krishnan, N., Felice, C., Rivera, K., Pappin, D. J., Tonks, N. K. (July 2018) DPM-1001 decreased copper levels and ameliorated deficits in a mouse model of Wilson's disease. Genes Dev, 32 (13-14). pp. 944-952. ISSN 0890-9369

Zhang, Jiali, Wang, Zuo, Zhang, Siwei, Chen, Yanxun, Xiong, Xuexue, Li, Xiaojuan, Tonks, Nicholas K., Fan, Gaofeng (June 2018) Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER. Cellular Signalling, 50. pp. 100-110. ISSN 0898-6568

Krishnan, N., Konidaris, K. F., Gasser, G., Tonks, N. K. (February 2018) A potent, selective and orally bioavailable inhibitor of the protein tyrosine phosphatase PTP1B improves insulin and leptin signaling in animal models. J Biol Chem, 293 (5). pp. 1517-1525. ISSN 0021-9258

Krishnan, N., Bonham, C. A., Rus, I. A., Shrestha, O. K., Gauss, C. M., Haque, A., Tocilj, A., Joshua-Tor, L., Tonks, N. K. (January 2018) Harnessing insulin- and leptin-induced oxidation of PTP1B for therapeutic development. Nat Commun, 9 (1). p. 283. ISSN 2041-1723

Zhang, S., Fan, G., Hao, Y., Hammell, M., Wilkinson, J. E., Tonks, N. K. (October 2017) Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase. Genes Dev, 31 (19). pp. 1939-57. ISSN 0890-9369

Gurung, Prajwal, Fan, Gaofeng, Lukens, John R., Vogel, Peter, Tonks, Nicholas K., Kanneganti, Thirumala-Devi (April 2017) Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease. Immunity, 46 (4). pp. 635-648. ISSN 1074-7613

Thompson, D., Morrice, N., Grant, L., Le Sommer, S., Lees, E. K., Tonks, N. K., Mody, N., Wilson, H. M., Delibegovic, M. (March 2017) Genetic deletion and pharmacological inhibition of macrophage protein tyrosine phosphatase 1B (PTP1B) improves global glucose and lipid homeostasis and protects against atherosclerotic plaque formation in mouse models of atherosclerosis. Diabetic Medicine, 34 (Supple). pp. 26-27. ISSN 0742-3071

Fan, G., Zhang, S., Gao, Y., Greer, P. A., Tonks, N. K. (July 2016) HGF-independent regulation of MET and GAB1 by nonreceptor tyrosine kinase FER potentiates metastasis in ovarian cancer. Genes Dev, 30 (13). pp. 1542-57. ISSN 1549-5477 (Electronic)0890-9369 (Linking)

Krishnan, Navasona, Tonks, Nicholas K. (August 2015) Anxious moments for the protein tyrosine phosphatase PTP1B. Trends in Neurosciences, 38 (8). pp. 462-465. ISSN 0166-2236

Moskal, D., Tonks, N. K., Lucito, R. (August 2015) Alteration of the protein tyrosine phosphatome in cancer. Cancer Research, 75 (Supple). Abstract 1933. ISSN 0008-5472

Krishnan, N., Krishnan, K., Connors, C. R., Choy, M. S., Page, R., Peti, W., Van Aelst, L., Shea, S. D., Tonks, N. K. (July 2015) PTP1B inhibition suggests a therapeutic strategy for Rett syndrome. J Clin Invest, 125 (8). pp. 3163-3177. ISSN 1558-8238 (Electronic)0021-9738 (Linking)

Fan, G., Aleem, S., Yang, M., Miller, W. T., Tonks, N. K. (June 2015) Protein Tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and BRK. Journal of Biological Chemistry, 290 (26). pp. 15934-15947. ISSN 0021-9258

Ramesh, M., Krishnan, N., Muthuswamy, S. K., Tonks, N. K. (April 2015) A Novel Phosphatidic Acid-Protein Tyrosine Phosphatase D2 Axis is Essential for ERBB2 Signaling in Mammary Epithelial Cells. Journal of Biological Chemistry, 290 (15). pp. 9646-9659. ISSN 0021-9258

Fan, G., Wrzeszczynski, K. O., Fu, C., Su, G., Pappin, D. J., Lucito, R., Tonks, N. K. (February 2015) A quantitative proteomics-based signature of platinum sensitivity in ovarian cancer cell lines. Biochem J, 465 (3). pp. 433-42. ISSN 0264-6021

Boivin, Benoit, Tonks, Nicholas K (2015) PTP1B: mediating ROS signaling to silence genes. Molecular and Cellular Oncology, 2 (2). e975633. ISSN 2372-3556

Chaudhary, F., Lucito, R., Tonks, N. K. (October 2014) Missing-in-Metastasis regulates cell motility and invasion via PTPdelta-mediated changes in SRC activity. Biochemical Journal, 465 (1). pp. 89-101. ISSN 0264-6021

Tonks, N., Lucito, R. (October 2014) Global assessment of the protein tyrosine phosphatome in cancer. Cancer Research, 74 (19). ISSN 0008-5472

Yang, M., Haase, A. D., Huang, F. K., Coulis, G., Rivera, K. D., Dickinson, B. C., Chang, C. J., Pappin, D. J., Neubert, T. A., Hannon, G. J., Boivin, B., Tonks, N. K. (August 2014) Dephosphorylation of Tyrosine 393 in Argonaute 2 by Protein Tyrosine Phosphatase 1B Regulates Gene Silencing in Oncogenic RAS-Induced Senescence. Mol Cell, 55 (5). pp. 782-790. ISSN 1097-2765

Pulido, R., Baker, S. J., Barata, J. T., Carracedo, A., Cid, V. J., Chin-Sang, I. D., Dave, V., den Hertog, J., Devreotes, P., Eickholt, B. J., Eng, C., Furnari, F. B., Georgescu, M. M., Gericke, A., Hopkins, B., Jiang, X., Lee, S. R., Losche, M., Malaney, P., Matias-Guiu, X., Molina, M., Pandolfi, P. P., Parsons, R., Pinton, P., Rivas, C., Rocha, R. M., Rodriguez, M. S., Ross, A. H., Serrano, M., Stambolic, V., Stiles, B., Suzuki, A., Tan, S. S., Tonks, N. K., Trotman, L. C., Wolff, N., Woscholski, R., Wu, H., Leslie, N. R. (July 2014) A Unified Nomenclature and Amino Acid Numbering for Human PTEN. Science signaling, 7 (332). pe15. ISSN 1937-9145

Schwertassek, U., Haque, A., Krishnan, N., Greiner, R., Weingarten, L., Dick, T. P., Tonks, N. K. (June 2014) Reactivation of oxidized PTP1B and PTEN by Thioredoxin 1. Febs Journal, 281 (16). pp. 3545-3558. ISSN 1742-464X

Krishnan, N., Koveal, D., Miller, D. H., Xue, B., Akshinthala, S. D., Kragelj, J., Jensen, M. R., Gauss, C. M., Page, R., Blackledge, M., Muthuswamy, S. K., Peti, W., Tonks, N. K. (May 2014) Targeting the disordered C terminus of PTP1B with an allosteric inhibitor. Nature Chemical Biology, 10 (7). pp. 558-566. ISSN 15524450

Mondol, A. S., Tonks, N. K., Kamata, T. (February 2014) Nox4 redox regulation of PTP1B contributes to the proliferation and migration of glioblastoma cells by modulating tyrosine phosphorylation of coronin-1C. Free Radical Biology and Medicine, 67. pp. 285-91. ISSN 0891-5849

Boivin, B., Chaudhary, F., Dickinson, B. C., Haque, A., Pero, S. C., Chang, C. J., Tonks, N. K. (November 2013) Receptor protein-tyrosine phosphatase α regulates focal adhesion kinase phosphorylation and ErbB2 oncoprotein mediated mammary epithelial cell motility. Journal of Biological Chemistry, 288 (52). pp. 36926-36935. ISSN 00219258 (ISSN)

Dagnell, M., Frijhoff, J., Pader, I., Augsten, M., Boivin, B., Xu, J., Mandal, P. K., Tonks, N. K., Hellberg, C., Conrad, M., Arnér, E. S. J., Östman, A. (August 2013) Selective activation of oxidized PTP1B by the thioredoxin system modulates PDGF-ß receptor tyrosine kinase signaling. Proceedings of the National Academy of Sciences of the United States of America, 110 (33). pp. 13398-13403. ISSN 00278424

Fan, G., Lin, G., Lucito, R., Tonks, N. K. (June 2013) Protein Tyrosine Phosphatase 1B Antagonized Signaling by IGF-1 Receptor and BRK/PTK6 in Ovarian Cancer Cells. Journal of Biological Chemistry, 288 (34). pp. 24923-29434. ISSN 0021-9258

Tonks, N. K. (April 2013) Protein Tyrosine Phosphatases: Critical Regulators of Signaling in Cancer. Faseb Journal, 27 (1). ISSN 0892-6638

Krishnan, N., Bencze, G., Cohen, P., Tonks, N. K. (April 2013) The anti-inflammatory compound BAY 11-7082 is a potent inhibitor of Protein Tyrosine Phosphatases. FEBS Journal, 280 (12). pp. 2830-2841. ISSN 1742-464X

Wrzeszczynski, K. O., Fan, G. F., Fu, C. X., Pappin, D. J., Lucito, R., Tonks, N. K. (April 2013) Proteomic identification of carboplatin resistance in ovarian cancer cells. Cancer Research, 73 (8 Supp). p. 2502. ISSN 0008-5472

Lindtner, C., Scherer, T., Zielinski, E., Filatova, N., Fasshauer, M., Tonks, N. K., Puchowicz, M., Buettner, C. (January 2013) Binge Drinking Induces Whole-Body Insulin Resistance by Impairing Hypothalamic Insulin Action. Science Translational Medicine, 5 (170). ISSN 1946-6234

Tonks, N. K. (January 2013) Protein tyrosine phosphatases - from housekeeping enzymes to master regulators of signal transduction. Febs Journal, 280 (2). pp. 346-378. ISSN 1742464X

Haque, A., Tonks, N. K. (November 2012) The use of phage display to generate conformation-sensor recombinant antibodies. Nature Protocols, 7 (12). pp. 2127-43. ISSN 1745-2473

Tonks, N. (November 2012) HARNESSING REDOX REGULATION OF PROTEIN TYROSINE PHOSPHATASES. Free Radical Biology and Medicine, 53 (Supple). S3-S3. ISSN 0891-5849

Yu, M., Lin, G., Arshadi, N., Kalatskaya, I., Xue, B., Haider, S., Nguyen, F., Boutros, P. C., Elson, A., Muthuswamy, L. B., Tonks, N. K., Muthuswamy, S. K. (October 2012) Expression profiling during mammary epithelial cell 3D morphogenesis identifies PTPRO as a novel regulator of morphogenesis and ErbB2 mediated transformation. Mol Cell Biol, 32 (19). pp. 3913-3924. ISSN 1098-5549 (Electronic)0270-7306 (Linking)

Zhang, X. C., Piccini, A., Myers, M. P., Van Aelst, L., Tonks, N. K. (June 2012) Functional analysis of the protein phosphatase activity of PTEN. Biochem J, 444 (3). pp. 457-64. ISSN 1470-8728 (Electronic)0264-6021 (Linking)

Haque, Aftabul, Andersen, J. N., Salmeen, A., Barford, D., Tonks, N. K. (September 2011) Conformation-Sensing Antibodies Stabilize the Oxidized Form of PTP1B and Inhibit Its Phosphatase Activity. Cell, 147 (1). pp. 185-198. ISSN 0092-8674

Lin, G., Aranda, V., Muthuswamy, S. K., Tonks, N. K. (July 2011) Identification of PTPN23 as a novel regulator of cell invasion in mammary epithelial cells from a loss-of-function screen of the 'PTP-ome'. Genes & Development, 25 (13). pp. 1412-1425. ISSN 0890-9369

Hyun, S. W., Anglin, I. E., Liu, A., Yang, S., Sorkin, J. D., Lillehoj, E., Tonks, N. K., Passaniti, A., Goldblum, S. E. (2011) Diverse injurious stimuli reduce protein tyrosine phosphatase-μ expression and enhance epidermal growth factor receptor signaling in human airway epithelia. Experimental Lung Research, 37 (6). pp. 327-343. ISSN 01902148 (ISSN)

Krishnan, N., Fu, C., Pappin, D. J., Tonks, N. K. (2011) H2S-induced sulfhydration of the phosphatase PTP1B and its role in the endoplasmic reticulum stress response. Science Signaling, 4 (203). ISSN 19450877 (ISSN)

Boivin, B., Tonks, N. K. , Yang, M. (August 2010) Targeting the reversibly oxidized protein tyrosine phosphatase superfamily. Science Signaling, 3 (137).

Schwertassek, U., Buckley, D. A., Xu, C. F., Lindsay, A. J., McCaffrey, M. W., Neubert, T. A., Tonks, N. K. (June 2010) Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis. Febs Journal, 277 (11). pp. 2463-2473. ISSN 1742-464X

Hinton, S. D., Myers, M. P., Roggero, V. R., Allison, L. A., Tonks, N. K. (May 2010) The pseudophosphatase MK-STYX interacts with G3BP and decreases stress granule formation. Biochemical Journal, 427. pp. 349-357. ISSN 0264-6021

Jung, S. K., Jeong, D. G., Chung, S. J., Kim, J. H., Park, B. C., Tonks, N. K., Ryu, S. E., Kim, S. J. (February 2010) Crystal structure of ED-Eya2: insight into dual roles as a protein tyrosine phosphatase and a transcription factor. FASEB J., 24 (2). pp. 560-569. ISSN 0892-6638

Tonks, N. K. (October 2009) Pseudophosphatases: grab and hold on. Cell, 139 (3). pp. 464-5.

Loh, K., Deng, H., Fukushima, A., Cai, X., Boivin, B., Galic, S., Bruce, C., Shields, B. J., Skiba, B., Ooms, L. M., Stepto, N., Wu, B., Mitchell, C. A., Tonks, N. K., Watt, M. J., Febbraio, M. A., Crack, P. J., Andrikopoulos, S., Tiganis, T. (October 2009) Reactive Oxygen Species Enhance Insulin Sensitivity. Cell Metabolism, 10 (4). pp. 260-272.

Krishnan, N., Jeong, D. G., Jung, S.-k., Ryu, S. E., Xiao, A., Allis, C. D., Kim, S. J., Tonks, N. K. (June 2009) Dephosphorylation of the C-terminal tyrosyl residue of the DNA damage-related histone H2A.X is mediated by the protein phosphatase eyes absent. Journal of Biological Chemistry, 284 (24). pp. 16066-16070.

Hemmings, B. A., Restuccia, D., Tonks, N. K. (April 2009) Targeting the Kinome II. Curr Opin Cell Biol, 21 (2). pp. 135-139.

Boivin, B., Zhang, S. H., Arbiser, J. L., Zhang, Z.-Y., Tonks, N. K. (July 2008) A modified cysteinyl-labeling assay reveals reversible oxidation of classical and dual specificity phosphatases in angiomyolipoma cells. Proc Natl Acad Sci U S A, 105 (29). pp. 9959-9964.

Tabet, F., Schiffrin, E. L., Callera, G., He, Y., Yao, G., Ostman, A., Kappert, K., Tonks, N. K., Touyz, R. M. (July 2008) Redox-Sensitive Signaling by Angiotensin II Involves Oxidative Inactivation and Blunted Phosphorylation of Protein Tyrosine Phosphatase SHP-2 in Vascular Smooth Muscle Cells From SHR. Circ Res, 103 (2). pp. 149-158.

Juarez, J. C., Manuia, M., Burnett, M. E., Betancourt, O., Boivin, B., Shaw, D. E., Tonks, N. K., Mazar, A. P., Donate, F. (May 2008) Superoxide dismutase 1 (SOD1) is essential for H2O2-mediated oxidation and inactivation of phosphatases in growth factor signaling. Proc Natl Acad Sci U S A, 105 (20). pp. 7147-7152. ISSN 0027-8424

Lou, Y.-W., Chen, Y.-Y., Hsu, S.-F., Chen, R.-K., Lee, C.-L., Khoo, K.-H., Tonks, N. K., Meng, T.-C. (January 2008) Redox regulation of the protein tyrosine phosphatase PTP1B in cancer cells. FEBS Journal, 275 (1). pp. 69-88.

Tonks, N., Krishnan, N. (2008) Regulation of Protein Tyrsoine Phosphatase by Hydrogen Sulphide. Free Radical Biology and Medicine, 45 (Suppl.). S18-S19. ISSN 0891-5849

Tonks, N., Krishnan, N. (2008) Unraveling the Mechanism of Redox Regulation in Protein Tyrosine Phosphatases. Free Radical Biology and Medicine, 45 (Suppl.). S62-S62. ISSN 0891-5849

Tonks, N. K. (October 2007) The protein tyrosine phosphatase superfamily of enzymes. Toxicology Letters, 172 (Supple). S10-S11. ISSN 0378-4274

Tonks, N. K., Muthuswamy, S. K. (March 2007) A Brake Becomes an Accelerator: PTP1B-A New Therapeutic Target for Breast Cancer. Cancer Cell, 11 (3). pp. 214-6. ISSN 1535-6108 (Print)

Tonks, N. K. (November 2006) Protein tyrosine phosphatases: from genes, to function, to disease. Nat Rev Mol Cell Biol, 7 (11). pp. 833-46. ISSN 1471-0072 (Print)

Nelson, K. K., Subbaram, S., Connor, K. M., Dasgupta, J., Ha, X. F., Meng, T. C., Tonks, N. K., Melendez, J. A. (2006) Redox-dependent matrix metalloproteinase-1 expression is regulated by JNK through Ets and AP-1 promoter motifs. Journal of Biological Chemistry, 281 (20). pp. 14100-14110. ISSN 00219258

Tonks, N. K. (June 2005) Redox redux: revisiting PTPs and the control of cell signaling. Cell, 121 (5). pp. 667-70. ISSN 0092-8674 (Print)

Sui, X. F., Kiser, T. D., Hyun, S. W., Angelini, D. J., Del Vecchio, R. L., Young, B. A., Hasday, J. D., Romer, L. H., Passaniti, A., Tonks, N. K., Goldblum, S. E. (April 2005) Receptor protein tyrosine phosphatase mu regulates the paracellular pathway in human lung microvascular endothelia. American Journal of Pathology, 166 (4). pp. 1247-1258. ISSN 0002-9440

Del Vecchio, R. L., Tonks, N. K. (January 2005) The conserved immunoglobulin domain controls the subcellular localization of the homophilic adhesion receptor protein-tyrosine phosphatase mu. J Biol Chem, 280 (2). pp. 1603-12. ISSN 0021-9258 (Print)

Andersen, J. N., Del Vecchio, R. L., Kannan, N., Gergel, J., Neuwald, A. F., Tonks, N.K. (January 2005) Computational analysis of protein tyrosine phosphatases: practical guide to bioinformatics and data resources. Methods, 35 (1). pp. 90-114. ISSN 1046-2023 (Print)

Galic, S., Hauser, C., Kahn, B. B., Haj, F. G., Neel, B. G., Tonks, N. K., Tiganis, T. (January 2005) Coordinated regulation of insulin signaling by the protein tyrosine phosphatases PTP1B and TCPTP. Molecular and Cellular Biology, 25 (2). pp. 819-829. ISSN 0270-7306

Meng, T. C., Hsu, S. F., Tonks, N. K. (January 2005) Development of a modified in-gel assay to identify protein tyrosine phosphatases that are oxidized and inactivated in vivo. Methods, 35 (1). pp. 28-36. ISSN 1046-2023

Hyun, S. W., Sui, X., Del Vecchio, R. L., Tonks, N. K., Passaniti, A., Goldblum, S. E. (November 2004) Protein tyrosine phosphatase (PTP) mu regulates endothelial cell (EC) proliferation, adhesion and migration. Molecular Biology of the Cell, 15. 226A-226A. ISSN 1059-1524

Sui, X., Hyun, S. W., Kiser, T. D., Del Vecchio, R. L., Tonks, N. K., Passaniti, A., Goldblum, S. E. (November 2004) Receptor protein tyrosine phosphatase (PTP) mu regulates the endothelial paracellular pathway. Molecular Biology of the Cell, 15. 428A-428A. ISSN 1059-1524

Chen, H. H., Luche, R., Wei, B., Tonks, N. K. (October 2004) Characterization of two distinct dual specificity phosphatases encoded in alternative open reading frames of a single gene located on human chromosome 10q22.2. J Biol Chem, 279 (40). pp. 41404-13. ISSN 0021-9258 (Print)

Meng, T. C., Buckley, D. A., Galic, S., Tiganis, T., Tonks, N. K. (September 2004) Regulation of insulin signaling through reversible oxidation of the protein-tyrosine phosphatases TC45 and PTP1B. J Biol Chem, 279 (36). pp. 37716-25. ISSN 0021-9258 (Print)

Bukczynska, P., Klingler-Hoffmann, M., Mitchelhill, K. I., Lam, M. H. C., Ciccomancini, M., Tonks, N. K., Sarcevic, B., Kemp, B. E., Tiganis, T. (June 2004) The T-cell protein tyrosine phosphatase is phosphorylated on Ser-304 by cyclin-dependent protein kinases in mitosis. Biochemical Journal, 380. pp. 939-949. ISSN 0264-6021

Andersen, J. N., Jansen, P. G., Echwald, S. M., Mortensen, O. H., Fukada, T., Del Vecchio, R., Tonks, N. K., Moller, N. P. (January 2004) A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes, and genetic disease linkage. FASEB J, 18 (1). pp. 8-30. ISSN 1530-6860 (Electronic)

Torres, J., Rodriguez, J., Myers, M. P., Valiente, M., Graves, J. D., Tonks, N. K., Pulido, R. (August 2003) Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3 - Implications for the control of protein stability and PTEN-protein interactions. Journal of Biological Chemistry, 278 (33). pp. 30652-30660. ISSN 0021-9258

Tonks, N. K. (July 2003) PTP1B: From the sidelines to the front lines! Febs Letters, 546 (1). pp. 140-148. ISSN 0014-5793

Gray, C. H., Good, V. M., Tonks, N. K., Barford, D. (July 2003) The structure of the cell cycle protein Cdc14 reveals a proline-directed protein phosphatase. Embo Journal, 22 (14). pp. 3524-3535. ISSN 0261-4189

Salmeen, A., Andersen, J. N., Myers, M. P., Meng, T. C., Hinks, J. A., Tonks, N. K., Barford, D. (June 2003) Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate. Nature, 423 (6941). pp. 769-773. ISSN 0028-0836

Galic, S., Klingler-Hoffmann, M., Fodero-Tavoletti, M. T., Puryer, M. A., Meng, T. C., Tonks, N. K., Tiganis, T. (March 2003) Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP. Molecular and Cellular Biology, 23 (6). pp. 2096-2108. ISSN 0270-7306

Palka, H. L., Park, M., Tonks, N. K. (February 2003) Hepatocyte growth factor receptor tyrosine kinase met is a substrate of the receptor protein-tyrosine phosphatase DEP-1. Journal of Biological Chemistry, 278 (8). pp. 5728-35. ISSN 0021-9258

Fukada, T., Tonks, N. K. (February 2003) Identification of YB-1 as a regulator of PTP1B expression: implications for regulation of insulin and cytokine signaling. Embo Journal, 22 (3). pp. 479-493. ISSN 0261-4189

Yart, A., Roche, S., Wetzker, R., Laffargue, M., Tonks, N., Mayeux, P., Chap, H., Raynal, P. (June 2002) A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid. Journal of Biological Chemistry, 277 (24). pp. 21167-21178. ISSN 0021-9258

Harrington, R. J., Gutch, M. J., Hengartner, M. O., Tonks, N. K., Chisholm, A. D. (May 2002) The C-elegans LAR-like receptor tyrosine phosphatase PTP-3 and the VAB-1 Eph receptor tyrosine kinase have partly redundant functions in morphogenesis. Development, 129 (9). pp. 2141-2153. ISSN 0950-1991

Boettner, B., Van Aelst, L. (March 2002) The role of Rho GTPases in disease development. Gene, 286 (2). pp. 155-74. ISSN 0378-1119 (Print)

Mayo, L. D., Dixon, J. E., Durden, D. L., Tonks, N. K., Donner, D. B. (February 2002) PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. Journal of Biological Chemistry, 277 (7). pp. 5484-5489. ISSN 0021-9258

Meng, T. C., Fukada, T., Tonks, N. K. (February 2002) Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Molecular Cell, 9 (2). pp. 387-399. ISSN 1097-2765

Nelson, K., Meng, T. C., Tonks, N., Melendez, J. A. (2002) Mitochondrial H2O2 enhances matrix metalloproteinase expression by protein tyrosine phosphatase inactivation. Free Radical Biology and Medicine, 33. S355-S355. ISSN 0891-5849

Myers, M. P., Andersen, J. N., Cheng, A., Tremblay, M. L., Horvath, C. M., Parisien, J. P., Salmeen, A., Barford, D., Tonks, N. K. (December 2001) TYK2 and JAR2 are substrates of protein-tyrosine phosphatase 1B. Journal of Biological Chemistry, 276 (51). pp. 47771-47774. ISSN 0021-9258

Shen, Y., Luche, R., Wei, B., Gordon, M. L., Diltz, C. D., Tonks, N. K. (November 2001) Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1. Proceedings of the National Academy of Sciences of the United States of America, 98 (24). pp. 13613-13618. ISSN 0027-8424

Sui, X., Kiser, T. D., Del Vecchio, R. L., Young, B. A., Gregoryev, D., Garcia, J. G. N., Tonks, N. K., Goldblum, S. E. (November 2001) PTP mu regulates the tyrosine phosphorylation state of VE-cadherin and the pulmonary microvascular endothelial paracellular pathway. Molecular Biology of the Cell, 12. 158A-158A. ISSN 1059-1524

Andersen, J. N., Mortensen, O. H., Peters, G. H., Drake, P. G., Iversen, L. F., Olsen, O. H., Jansen, P. G., Andersen, H. S., Tonks, N. K., Moller, N. P. H. (November 2001) Structural and evolutionary relationships among protein tyrosine phosphatase domains. Molecular and Cellular Biology, 21 (21). pp. 7117-7136. ISSN 0270-7306

Lam, M. H. C., Michell, B. J., Fodero-Tavoletti, M. T., Kemp, B. E., Tonks, N. K., Tiganis, T. (October 2001) Cellular stress regulates the nucleocytoplasmic distribution of the protein-tyrosine phosphatase TCPTP. Journal of Biological Chemistry, 276 (40). pp. 37700-37707. ISSN 0021-9258

Yang, J., Dokurno, P., Tonks, N. K., Barford, D. (July 2001) Crystal structure of the M-fragment of alpha-catenin: implications for modulation of cell adhesion. Embo Journal, 20 (14). pp. 3645-3656. ISSN 0261-4189

Fukada, T., Tonks, N. K. (July 2001) The reciprocal role of Egr-1 and Sp family proteins in regulation of the PTP1B promoter in response to the p210 Bcr-Abl oncoprotein-tyrosine kinase. Journal of Biological Chemistry, 276 (27). pp. 25512-25519. ISSN 0021-9258

Tonks, N. K., Neel, B. G. (April 2001) Combinatorial control of the specificity of protein tyrosine phosphatases. Current Opinion in Cell Biology, 13 (2). pp. 182-195. ISSN 0955-0674

Wen, S. H., Stolarov, J., Myers, M. P., Su, J. D., Wigler, M. H., Tonks, N. K., Durden, D. L. (April 2001) PTEN controls tumor-induced angiogenesis. Proceedings of the National Academy of Sciences of the United States of America, 98 (8). pp. 4622-4627. ISSN 0027-8424

Yart, A., Laffargue, M., Mayeux, P., Chretien, S., Peres, C., Tonks, N., Roche, S., Payrastre, B., Chap, H., Raynal, P. (March 2001) A critical pole for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of Ras and mitogen-activated protein kinases by epidermal growth factor. Journal of Biological Chemistry, 276 (12). pp. 8856-8864. ISSN 0021-9258

Salmeen, A., Andersen, J. N., Myers, M. P., Tonks, N. K., Barford, D. (December 2000) Molecular basis for the dephosphorylation of the activation segment of the insulin receptor by protein tyrosine phosphatase 1B. Molecular Cell, 6 (6). pp. 1401-1412. ISSN 1097-2765

Lavoie, C., Chevet, E., Roy, L., Tonks, N. K., Fazel, A., Posner, B. I., Paiement, J., Bergeron, J. J. M. (December 2000) Tyrosine phosphorylation of p97 regulates transitional endoplasmic reticulum assembly in vitro. Proceedings of the National Academy of Sciences of the United States of America, 97 (25). pp. 13637-13642. ISSN 0027-8424

Tonks, N. K. (March 2000) From structure to function of protein tyrosine phosphatases. Abstracts of Papers of the American Chemical Society, 219. U7-U7. ISSN 0065-7727

Tonks, N. K., Myers, M. P. (December 1999) Structural assets of a tumor suppressor. Science, 286 (5447). pp. 2096-2097. ISSN 0036-8075

Tiganis, T., Kemp, B. E., Tonks, N. K. (September 1999) The protein-tyrosine phosphatase TCPTP regulates epidermal growth factor receptor-mediated and phosphatidylinositol 3-kinase-dependent signaling. Journal of Biological Chemistry, 274 (39). pp. 27768-27775. ISSN 0021-9258

Zhang, S. H., Liu, J. P., Kobayashi, R., Tonks, N. K. (June 1999) Identification of the cell cycle regulator VCP (p97/CDC48) as a substrate of the band 4.1-related protein-tyrosine phosphatase PTPH1. Journal of Biological Chemistry, 274 (25). pp. 17806-17812. ISSN 0021-9258

Bianchi, C., Sellke, F. W., Del Vecchio, R. L., Tonks, N. K., Neel, B. G. (April 1999) Receptor-type protein-tyrosine phosphatase mu is expressed in specific vascular endothelial beds in vivo. Experimental Cell Research, 248 (1). pp. 329-338. ISSN 0014-4827

Garton, A. J., Tonks, N. K. (February 1999) Regulation of fibroblast motility by the protein tyrosine phosphatase PTP-PEST. Journal of Biological Chemistry, 274 (6). pp. 3811-3818. ISSN 0021-9258

Li, J., Simpson, L., Takahashi, M., Miliaresis, C., Myers, M. P., Tonks, N., Parsons, R. (December 1998) The PTEN/MMAC1 tumor suppressor induces cell death that is rescued by the AKT/protein kinase B oncogene. Cancer Research, 58 (24). pp. 5667-5672. ISSN 0008-5472

Myers, M. P., Pass, I., Batty, I. H., Van der Kaay, J., Stolarov, J. P., Hemmings, B. A., Wigler, M. H., Downes, C. P., Tonks, N. K. (November 1998) The lipid phosphatase activity of PTEN is critical for its tumor supressor function. Proc Natl Acad Sci U S A, 95 (23). pp. 13513-8. ISSN 0027-8424 (Print)

LaMontagne, K. R., Hannon, G., Tonks, N. K. (November 1998) Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells. Proceedings of the National Academy of Sciences of the United States of America, 95 (24). pp. 14094-14099. ISSN 0027-8424

La Montagne, K. R., Flint, A. J., Franza, B. R., Pendergast, A. M., Tonks, N. K. (May 1998) Protein tyrosine phosphatase 1B antagonizes signalling by oncoprotein tyrosine kinase p210 bcr-abl in vivo. Molecular and Cellular Biology, 18 (5). pp. 2965-2975. ISSN 0270-7306

Brady-Kalnay, S. M., Mourton, T., Nixon, J. P., Pietz, G. E., Kinch, M., Chen, H. Y., Brackenbury, R., Rimm, D. L., Del Vecchio, R. L., Tonks, N. K. (April 1998) Dynamic interaction of PTP mu with multiple cadherins in vivo. Journal of Cell Biology, 141 (1). pp. 287-296. ISSN 0021-9525

Pannifer, A. D. B., Flint, A. J., Tonks, N. K., Barford, D. (April 1998) Visualization of the cysteinyl-phosphate intermediate of a protein-tyrosine phosphatase by X-ray crystallography. Journal of Biological Chemistry, 273 (17). pp. 10454-10462. ISSN 0021-9258

Tiganis, T., Bennett, A. M., Ravichandran, K. S., Tonks, N. K. (March 1998) Epidermal growth factor receptor and the adaptor protein p52(Shc) are specific substrates of T-cell protein tyrosine phosphatase. Molecular and Cellular Biology, 18 (3). pp. 1622-1634. ISSN 0270-7306

Gutch, M. J., Flint, A. J., Keller, J., Tonks, N. K., Hengartner, M. O. (February 1998) The Caenorhabditis elegans SH2 domain-containing protein tyrosine phosphatase PTP-2 participates in signal transduction during oogenesis and vulval development. Genes & Development, 12 (4). pp. 571-585. ISSN 0890-9369

Tonks, N. K. (1998) From structure to function of protein tyrosine phosphatases. Naunyn-Schmiedebergs Archives of Pharmacology, 358 (1). R377-R377. ISSN 0028-1298

Myers, M. P., Tonks, N. K. (December 1997) PTEN: Sometimes taking it off can be better than putting it on. American Journal of Human Genetics, 61 (6). pp. 1234-1238. ISSN 0002-9297

Bennett, A. M., Tonks, N. K. (November 1997) Regulation of distinct stages of skeletal muscle differentiation by mitogen-activated protein kinases. Science, 278 (5341). pp. 1288-1291. ISSN 0036-8075

Hao, L. N., Tiganis, T., Tonks, N. K., Charbonneau, H. (November 1997) The noncatalytic C-terminal segment of the T cell protein tyrosine phosphatase regulates activity via an intramolecular mechanism. Journal of Biological Chemistry, 272 (46). pp. 29322-29329. ISSN 0021-9258

Zhang, S. H., Kobayashi, R., Graves, P. R., Piwnica-Worms, H., Tonks, N. K. (October 1997) Serine phosphorylation-dependent association of the band 4.1-related protein-tyrosine phosphatase PTPH1 with 14-3-3 beta protein. Journal of Biological Chemistry, 272 (43). pp. 27281-27287. ISSN 0021-9258

Hoffmann, K. M. V., Tonks, N. K., Barford, D. (October 1997) The crystal structure of domain 1 of receptor protein-tyrosine phosphatase mu. Journal of Biological Chemistry, 272 (44). pp. 27505-27508. ISSN 0021-9258

Myers, M. P., Stolarov, J. P., Eng, C., Li, J., Wang, S. I., Wigler, M. H., Parsons, R., Tonks, N. K. (August 1997) P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A, 94 (17). pp. 9052-7. ISSN 0027-8424 (Print)

Garton, A. J., Burnham, M. R., Bouton, A. H., Tonks, N. K. (August 1997) Association of PTP-PEST with the SH3 domain of p130(cas); a novel mechanism of protein tyrosine phosphatase substrate recognition. Oncogene, 15 (8). pp. 877-885. ISSN 0950-9232

Tiganis, T., Flint, A. J., Adam, S. A., Tonks, N. K. (August 1997) Association of the T-cell protein tyrosine phosphatase with nuclear import factor p97. Journal of Biological Chemistry, 272 (34). pp. 21548-21557. ISSN 0021-9258

Tonks, N. K. (July 1997) From structure to function of protein tyrosine phosphatases. Faseb Journal, 11 (9). A1012-A1012. ISSN 0892-6638

Fuller, S. J., Davies, E. L., Gillespie Brown, J., Sun, H., Tonks, N. K. (April 1997) Mitogen-activated protein kinase phosphatase 1 inhibits the stimulation of gene expression by hypertrophic agonists in cardiac myocytes. Biochemical Journal, 323. pp. 313-319. ISSN 0264-6021

Neel, B. G., Tonks, N. K. (April 1997) Protein tyrosine phosphatases in signal transduction. Current Opinion in Cell Biology, 9 (2). pp. 193-204. ISSN 0955-0674

Flint, A. J., Tiganis, T., Barford, D., Tonks, N. K. (March 1997) Development of ''substrate-trapping'' mutants to identify physiological substrates of protein tyrosine phosphatases. Proceedings of the National Academy of Sciences of the United States of America, 94 (5). pp. 1680-1685. ISSN 0027-8424

Zhang, S. H., Tonks, N. K. (December 1996) Phosphorylation-dependent association of band 4.1-related protein tyrosine phosphatase PTPH1 and 14-3-3B. Molecular Biology of the Cell, 7. p. 83. ISSN 1059-1524

Tonks, N. K., Neel, B. G. (November 1996) From form to function: Signaling by protein tyrosine phosphatases. Cell, 87 (3). pp. 365-368. ISSN 0092-8674

MacKintosh, C., Garton, A. J., McDonnell, A., Barford, D., Cohen, P. T. W., Tonks, N. K., Cohen, P. (November 1996) Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation. Febs Letters, 397 (2-3). pp. 235-238. ISSN 0014-5793

Garton, A. J., Flint, A. J., Tonks, N. K. (November 1996) Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST. Molecular and Cellular Biology, 16 (11). pp. 6408-6418. ISSN 0270-7306

Park, C. Y., La Montagne, K. R., Tonks, N. K., Hayman, M. J. (October 1996) Cloning and expression of the chicken protein tyrosine phosphatase SH-PTP2. Gene, 177 (1-2). pp. 93-97. ISSN 0378-1119

Tonks, N. K. (April 1996) Protein tyrosine phosphatases and the control of the cellular signalling responses. Faseb Journal, 10 (6). P13-P13. ISSN 0892-6638

Tonks, N. K. (1996) Protein tyrosine phosphatases and the control of cellular signaling responses. Advances in Pharmacology, 36. pp. 91-119. ISSN 1054-3589 (Print)

Barford, D., Jia, Z. C., Tonks, N. K. (December 1995) Protein tyrosine phosphatases take off. Nature Structural Biology, 2 (12). pp. 1043-1053. ISSN 1072-8368

Brady-Kalnay, S. M., Rimm, D. L., Tonks, N. K. (November 1995) The receptor protein-tyrosine-phosphatase PTP-mu associates with cadherins and catenins. Molecular Biology of the Cell, 6. p. 676. ISSN 1059-1524

Brady-Kalnay, S. M., Tonks, N. K. (October 1995) Protein tyrosine phosphatases as adhesion receptors. Current Opinion in Cell Biology, 7 (5). pp. 650-657. ISSN 0955-0674

Zhang, S. H., Eckberg, W. R., Yang, Q., Samatar, A. A., Tonks, N. K. (August 1995) Biochemical characterization of a human band 4.1-related protein-tyrosine phosphatase, PTPH1. Journal of Biological Chemistry, 270 (34). pp. 20067-20072. ISSN 0021-9258

Brady-Kalnay, S. M., Rimm, D. L., Tonks, N. K. (August 1995) Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo. Journal of Cell Biology, 130 (4). pp. 977-986. ISSN 0021-9525

Jia, Z. C., Barford, D., Flint, A. J., Tonks, N. K. (June 1995) Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B. Science, 268 (5218). pp. 1754-1758. ISSN 0036-8075

Brondello, J. M., McKenzie, F. R., Sun, H., Tonks, N. K., Pouyssegur, J. (May 1995) Constitutive MAP kinase phosphatase (MKP-1) expression blocks G1 specific gene transcription and S-phase entry in fibroblasts. Oncogene, 10 (10). pp. 1895-1904. ISSN 0950-9232

La Montagne, K. R., Pendergast, A. M., Franza, B. R., Tonks, N. K. (January 1995) Enhanced expression of a protein-tyrosine phosphatase in cells expressing P210BCR/ABL. Journal of Cellular Biochemistry. p. 65. ISSN 0730-2312

Brady-Kalnay, S. M., Tonks, N. K. (November 1994) Identification of the homophilic binding site of the receptor protein tyrosine phosphatase PTP mu. Journal of Biological Chemistry, 269 (45). pp. 28472-28477. ISSN 0021-9258

Minshull, J., Sun, H., Tonks, N. K., Murray, A. W. (November 1994) A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts. Cell, 79 (3). pp. 475-486. ISSN 0092-8674

Sun, H., Tonks, N. K. (November 1994) The coordinated action of protein tyrosine phosphatases and kinases in cell signaling. Trends in Biochemical Sciences, 19 (11). pp. 480-485. ISSN 0968-0004

Ostman, A., Yang, Q., Tonks, N. K. (October 1994) Expression of DEP-1, a receptor-like protein-tyrosine-phosphatase, is enhanced with increasing cell density. Proceedings of the National Academy of Sciences of the United States of America, 91 (21). pp. 9680-9684. ISSN 0027-8424

Sun, H., Tonks, N. K., Barsagi, D. (October 1994) Inhibition of Ras-induced DNA synthesis by expression of the phosphatase MKP-1. Science, 266 (5183). pp. 285-288. ISSN 0036-8075

Garton, A. J., Tonks, N. K. (August 1994) PTP-PEST: a protein tyrosine phosphatase regulated by serine phosphorylation. Embo Journal, 13 (16). pp. 3763-3771. ISSN 0261-4189

Delvecchio, R. L., Tonks, N. K. (July 1994) Characterization of two structurally related Xenopus laevis protein tyrosine phosphatases with homology to lipid-binding proteins. Journal of Biological Chemistry, 269 (30). pp. 19639-19645. ISSN 0021-9258

Barford, D., Keller, J. C., Flint, A. J., Tonks, N. K. (June 1994) Purification and crystallization of the catalytic domain of human protein tyrosine phosphatase 1B expressed in Escherichia coli. Journal of Molecular Biology, 239 (5). pp. 726-730. ISSN 0022-2836

Tonks, N. K. (April 1994) Protein tyrosine phosphatases and the control of the cellular signalling responses. Faseb Journal, 8 (7). A1377-A1377. ISSN 0892-6638

Barford, D., Flint, A. J., Tonks, N. K. (March 1994) Crystal structure of human protein tyrosine phosphatase 1B. Science, 263 (5152). pp. 1397-1404.

Brady-Kalnay, S. M., Tonks, N. K. (March 1994) Protein tyrosine phosphatases: from structure to function. Trends Cell Biol, 4 (3). pp. 73-6. ISSN 0962-8924 (Print)

Sun, H., Charles, C. H., Lau, L. F., Tonks, N. K. (November 1993) MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell, 75 (3). pp. 487-493. ISSN 0092-8674

Brady-Kalnay, S. M., Tonks, N. K. (November 1993) Purification and characterization of the human protein tyrosine phosphatase, PTP mu, from a baculovirus expression system. Molecular and Cellular Biochemistry, 128. pp. 131-141. ISSN 0300-8177

Lammers, R., Bossenmaier, B., Cool, D. E., Tonks, N. K., Schlessinger, J., Fischer, E. H., Ullrich, A. (October 1993) Differential activities of protein tyrosine phosphatases in intact cells. Journal of Biological Chemistry, 268 (30). pp. 22456-22462. ISSN 0021-9258

Brady-Kalnay, S. M., Flint, A. J., Tonks, N. K. (August 1993) Homophilic binding of PTP mu, a receptor-type protein tyrosine phosphatase, can mediate cell-cell aggregation. Journal of Cell Biology, 122 (4). pp. 961-972. ISSN 0021-9525

Turner, B. C., Tonks, N. K., Rapp, U. R., Reed, J. C. (June 1993) Interleukin-2 Regulates Raf-1 Kinase-Activity through a Tyrosine Phosphorylation-Dependent Mechanism in a T-Cell Line. Proceedings of the National Academy of Sciences of the United States of America, 90 (12). pp. 5544-5548. ISSN 0027-8424

Charles, C. H., Sun, H., Lau, L. F., Tonks, N. K. (June 1993) The growth factor-inducible immediate-early gene 3CH134 encodes a protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 90 (11). pp. 5292-5296. ISSN 0027-8424

Flint, A. J., Gebbink, M. F., Franza, B. R., Hill, D. E., Tonks, N. K. (May 1993) Multi-site phosphorylation of the protein tyrosine phosphatase, PTP1B: identification of cell cycle regulated and phorbol ester stimulated sites of phosphorylation. Embo Journal, 12 (5). pp. 1937-1946. ISSN 0261-4189

Potts, M., Sun, H., Mockaitis, K., Kennelly, P. J., Reed, D., Tonks, N. K. (April 1993) A protein-tyrosine/serine phosphatase encoded by the genome of the cyanobacterium Nostoc commune UTEX 584. Journal of Biological Chemistry, 268 (11). pp. 7632-7635. ISSN 0021-9258

Yang, Q., Co, D., Sommercorn, J., Tonks, N. K. (March 1993) Cloning and expression of PTP-PEST. A novel, human, nontransmembrane protein tyrosine phosphatase. Journal of Biological Chemistry, 268 (9). pp. 6622-6628. ISSN 0021-9258

Tonks, N. K., Flint, A. J., Gebbink, M. F., Sun, H., Yang, Q. (1993) Signal transduction and protein tyrosine dephosphorylation. Adv Second Messenger Phosphoprotein Res, 28. pp. 203-10. ISSN 1040-7952 (Print)

Cool, D. E., Andreassen, P. R., Tonks, N. K., Krebs, E. G., Fischer, E. H., Margolis, R. L. (June 1992) Cytokinetic failure and asynchronous nuclear division in BHK cells overexpressing a truncated protein-tyrosine-phosphatase. Proceedings of the National Academy of Sciences of the United States of America, 89 (12). pp. 5422-5426. ISSN 0027-8424

Ramachandran, C., Aebersold, R., Tonks, N. K., Pot, D. A. (May 1992) Sequential dephosphorylation of a multiply phosphorylated insulin receptor peptide by protein tyrosine phosphatases. Biochemistry, 31 (17). pp. 4232-4238. ISSN 0006-2960

Charbonneau, H., Tonks, N. K. (1992) 1002 Protein Phosphatases? Annual Review of Cell Biology, 8. pp. 463-493. ISSN 0743-4634

Tonks, N. K., Yang, Q., Flint, A. J., Gebbink, M. F., Franza, B. R., Hill, D. E., Sun, H., Brady-Kalnay, S. M. (1992) Protein tyrosine phosphatases: the problems of a growing family. Cold Spring Harbor Symposia on Quantitative Biology, 57. pp. 87-94. ISSN 0091-7451

Fischer, E. H., Charbonneau, H., Cool, D. E., Tonks, N. K. (1992) Tyrosine phosphatases and their possible interplay with tyrosine kinases. Ciba Foundation Symposia, 164. pp. 132-144. ISSN 0300-5208

Sanghera, J. S., McNabb, C. K., Tonks, N., Pelech, S. L. (October 1991) Tyrosyl phosphorylation and activation of the myelin basic protein kinase p44mpk during sea star oocyte maturation. Biochimica Et Biophysica Acta, 1095 (2). pp. 153-160. ISSN 0006-3002

Stover, D. R., Charbonneau, H., Tonks, N. K., Walsh, K. A. (September 1991) Protein-tyrosine-phosphatase CD45 is phosphorylated transiently on tyrosine upon activation of Jurkat T cells. Proceedings of the National Academy of Sciences of the United States of America, 88 (17). pp. 7704-7707. ISSN 0027-8424

Tonks, N. K. (August 1991) Plague, pox and tyrosine dephosphorylation. Curr Biol, 1 (4). pp. 259-61.

McGuire, M. C., Fields, R. M., Nyomba, B. L., Raz, I., Bogardus, C., Tonks, N. K., Sommercorn, J. (July 1991) Abnormal regulation of protein tyrosine phosphatase activities in skeletal muscle of insulin-resistant humans. Diabetes, 40 (7). pp. 939-942. ISSN 0012-1797

Yang, Q., Tonks, N. K. (July 1991) Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin. Proceedings of the National Academy of Sciences of the United States of America, 88 (14). pp. 5949-5953. ISSN 0027-8424

Fischer, E. H., Charbonneau, H., Tonks, N. K. (July 1991) Protein tyrosine phosphatases: a diverse family of intracellular and transmembrane enzymes. Science, 253 (5018). pp. 401-406. ISSN 0036-8075

Zander, N. F., Lorenzen, J. A., Cool, D. E., Tonks, N. K., Daum, G., Krebs, E. G., Fischer, E. H. (July 1991) Purification and characterization of a human recombinant T-cell protein-tyrosine-phosphatase from a baculovirus expression system. Biochemistry, 30 (28). pp. 6964-6970. ISSN 0006-2960

Tonks, N. K., Diltz, C. D., Fischer, E. H. (1991) Purification and assay of CD45: an integral membrane protein-tyrosine phosphatase. Methods in Enzymology, 201. pp. 442-451. ISSN 0076-6879

Tonks, N. K., Diltz, C. D., Fischer, E. H. (1991) Purification of protein-tyrosine phosphatases from human placenta. Methods in Enzymology, 201. pp. 427-442. ISSN 0076-6879

Tonks, N. K., Yang, Q., Guida, P. (1991) Structure, regulation, and function of protein tyrosine phosphatases. Cold Spring Harbor Symposia on Quantitative Biology, 56. pp. 265-273. ISSN 0091-7451

Tonks, N. K. (December 1990) Protein phosphatases: key players in the regulation of cell function. Curr Opin Cell Biol, 2 (6). pp. 1114-24. ISSN 0955-0674 (Print)0955-0674 (Linking)

Book Section

Boivin, B., Tonks, N. K. (2010) Analysis of the redox regulation of protein tyrosine phosphatase superfamily members utilizing a cysteinyl-labeling assay. In: Thiol Redox Transitions in Cell Signaling, Part B: Cellular Localization and Signaling. Methods in Enzymology, 474 . Elsevier Academic Press Inc, San Diego, pp. 35-50. ISBN 0076-6879978-0-12-381003-8

Andersen, J. N., Tonks, N. K. (2004) Protein tyrosine phosphatase-based therapeutics- lessons from PTP1B. In: Protein phosphatases. Topics in current genetics, 5 . Springer-Verlag, Berlin, pp. 201-230. ISBN 3540205608

Meng, T. C., Tonks, N. K. (2003) Analysis of the regulation of protein tyrosine phosphatases in vivo by reversible oxidation. In: Protein Phosphatases. Methods in Enzymology, 366 . Academic Press Inc, San Diego, pp. 304-318. ISBN 0076-6879

Conference or Workshop Item

Londhe, Avinash, Boivin, Ben, Bergeron, Alexandre, Rizvi, Syed Husain Mustafa, Kim, Seung Jun, Rivera, Keith, Pappin, Darryl, Tonks, Nicholas (December 2019) 6Characterization of PTP1B Activation by Small Molecules. In: 26th Annual Meeting of the Society-for-Redox-Biology-and-Medicine (SFRBM).

Book

Neel, B.G., Tonks, N.K., eds. (2016) Protein Tyrosine Phosphatases in Cancer. Springer New York. ISBN 9781493936496

Video

Tonks, N. K. (November 2012) Talk from Nick Tonks at the Cold Spring Harbor Laboratory In-House Symposium (2012). [Video] (Unpublished)