Items where Community is "Lukey lab"

Paper

Qiu, Yijian, Stamatatos, Olivia T, Hu, Qingting, Ruiter Swain, Jed, Russo, Suzanne, Sann, Ava, Costa, Ana SH, Violante, Sara, Spector, David L, Cross, Justin R, Lukey, Michael J (August 2024) The unique catalytic properties of PSAT1 mediate metabolic adaptation to glutamine blockade. Nature Metabolism, 6 (8). pp. 1529-1548. ISSN 2522-5812 (Public Dataset)

Homer, Joshua A, Koelln, Rebecca A, Barrow, Andrew S, Gialelis, Timothy L, Boiarska, Zlata, Steinohrt, Nikita S, Lee, Erinna F, Yang, Wen-Hsuan, Johnson, Robert M, Chung, Taemoon, Habowski, Amber N, Vishwakarma, Dharmendra S, Bhunia, Debmalya, Avanzi, Charlotte, Moorhouse, Adam D, Jackson, Mary, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Fairlie, W Douglas, Haider, Shozeb M, Steinmetz, Michel O, Prota, Andrea E, Moses, John E (March 2024) Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chemical Science, 15 (11). pp. 3879-3892. ISSN 2041-6520 (Public Dataset)

de Ruiter Swain, Jed, Michalopoulou, Evdokia, Noch, Evan K, Lukey, Michael J, Van Aelst, Linda (August 2023) Metabolic partitioning in the brain and its hijacking by glioblastoma. Genes and Development, 37. pp. 681-702. ISSN 0890-9369

Gialelis, Timothy L, Wang, Zifei, Homer, Joshua A, Yang, Wen-Hsuan, Chung, Taemoon, Hu, Qingting, Smedley, Christopher J, Pawar, Nitin J, Upadhyay, Nitinkumar S, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Moses, John E (April 2023) Inhibition of mitochondrial metabolism by (-)-jerantinine A: synthesis and biological studies in triple-negative breast cancer cells. MedChemComm, 14 (4). pp. 710-714. ISSN 2632-8682

Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E, Kleeman, Sam O, Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Flint, Thomas R, Connell, Claire M, Lukey, Michael J, White, Eileen P, Coll, Anthony P, Venkitaraman, Ashok R, Janowitz, Tobias (February 2023) Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia. bioRxiv. (Submitted)

Petruzzelli, M, Ferrer, M, Schuijs, MJ, Kleeman, SO, Mourikis, N, Hall, Z, Perera, D, Raghunathan, S, Vacca, M, Gaude, E, Lukey, MJ, Jodrell, DI, Frezza, C, Wagner, EF, Venkitaraman, AR, Halim, TYF, Janowitz, T (February 2022) Early Neutrophilia Marked by Aerobic Glycolysis Sustains Host Metabolism and Delays Cancer Cachexia. Cancers, 14 (4). p. 963. ISSN 2072-6694

Yang, Wen-Hsuan, Qiu, Yijian, Stamatatos, Olivia, Janowitz, Tobias, Lukey, Michael J (May 2021) Enhancing the Efficacy of Glutamine Metabolism Inhibitors in Cancer Therapy. Trends in Cancer. ISSN 2405-8033

Lukey, M. J., Greene, K.S., Cerione, R.A. (March 2020) Lysine succinylation and SIRT5 couple nutritional status to glutamine catabolism. Mol Cell Oncol, 7 (3). p. 1735284. ISSN 2372-3556 (Electronic)2372-3556 (Linking)

Greene, K. S., Lukey, M. J., Wang, X., Blank, B., Druso, J. E., Lin, M. J., Stalnecker, C. A., Zhang, C., Negron Abril, Y., Erickson, J. W., Wilson, K. F., Lin, H., Weiss, R. S., Cerione, R. A. (December 2019) SIRT5 stabilizes mitochondrial glutaminase and supports breast cancer tumorigenesis. Proc Natl Acad Sci U S A. ISSN 1091-6490 (Public Dataset)

Lukey, M. J., Cluntun, A. A., Katt, W. P., Lin, M. J., Druso, J. E., Ramachandran, S., Erickson, J. W., Le, H. H., Wang, Z. E., Blank, B., Greene, K. S., Cerione, R. A. (October 2019) Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer. Cell Rep, 29 (1). 76-88 e7. ISSN 2211-1247

Katt, W. P., Lukey, M. J., Cerione, R. A. (September 2019) Starving the Devourer: Cutting Cancer Off from Its Favorite Foods. Cell Chem Biol, 26 (9). pp. 1197-1199. ISSN 2451-9448

Antonyak, M. A., Lukey, M. J., Cerione, R. A. (March 2019) Lipid-filled vesicles modulate macrophages. Science, 363 (6430). pp. 931-932. ISSN 1095-9203

Lukey, M. J., Katt, W. P., Cerione, R. A. (May 2018) Targeting Therapy Resistance: When Glutamine Catabolism Becomes Essential. Cancer Cell, 33 (5). pp. 795-797. ISSN 1878-3686

Lukey, M. J., Katt, W. P., Cerione, R. A. (May 2017) Targeting amino acid metabolism for cancer therapy. Drug Discov Today, 22 (5). pp. 796-804. ISSN 1878-5832

Cluntun, A. A., Lukey, M. J., Cerione, R. A., Locasale, J. W. (March 2017) Glutamine Metabolism in Cancer: Understanding the Heterogeneity. Trends Cancer, 3 (3). pp. 169-180. ISSN 2405-8033

Katt, W. P., Lukey, M. J., Cerione, R. A. (January 2017) A tale of two glutaminases: homologous enzymes with distinct roles in tumorigenesis. Future Med Chem, 9 (2). pp. 223-243. ISSN 1756-8927

Lukey, M. J., Greene, K. S., Erickson, J. W., Wilson, K. F., Cerione, R. A. (April 2016) The oncogenic transcription factor c-Jun regulates glutaminase expression and sensitizes cells to glutaminase-targeted therapy. Nat Commun, 7. p. 11321. ISSN 2041-1723

Lukey, MJ, Cerione, RA (January 2016) The regulation of cancer cell glutamine metabolism. Translational Cancer Research, 5 (S6). S1297-S1298. ISSN 2218-676X

Lukey, M. J., Wilson, K. F., Cerione, R. A. (September 2013) Therapeutic strategies impacting cancer cell glutamine metabolism. Future Med Chem, 5 (14). pp. 1685-700. ISSN 1756-8927

Evans, R. M., Parkin, A., Roessler, M. M., Murphy, B. J., Adamson, H., Lukey, M. J., Sargent, F., Volbeda, A., Fontecilla-Camps, J. C., Armstrong, F. A. (February 2013) Principles of sustained enzymatic hydrogen oxidation in the presence of oxygen--the crucial influence of high potential Fe-S clusters in the electron relay of [NiFe]-hydrogenases. J Am Chem Soc, 135 (7). pp. 2694-707. ISSN 1520-5126

Rollauer, S. E., Tarry, M. J., Graham, J. E., Jaaskelainen, M., Jager, F., Johnson, S., Krehenbrink, M., Liu, S. M., Lukey, M. J., Marcoux, J., McDowell, M. A., Rodriguez, F., Roversi, P., Stansfeld, P. J., Robinson, C. V., Sansom, M. S., Palmer, T., Hogbom, M., Berks, B. C., Lea, S. M. (December 2012) Structure of the TatC core of the twin-arginine protein transport system. Nature, 492 (7428). pp. 210-4. ISSN 1476-4687 (Public Dataset)

Lukey, M. J., Roessler, M. M., Parkin, A., Evans, R. M., Davies, R. A., Lenz, O., Friedrich, B., Sargent, F., Armstrong, F. A. (October 2011) Oxygen-tolerant [NiFe]-hydrogenases: the individual and collective importance of supernumerary cysteines at the proximal Fe-S cluster. J Am Chem Soc, 133 (42). pp. 16881-92. ISSN 1520-5126

Lazarus, O., Woolerton, T. W., Parkin, A., Lukey, M. J., Reisner, E., Seravalli, J., Pierce, E., Ragsdale, S. W., Sargent, F., Armstrong, F. A. (October 2009) Water-gas shift reaction catalyzed by redox enzymes on conducting graphite platelets. J Am Chem Soc, 131 (40). pp. 14154-5. ISSN 1520-5126

Book Section

Lukey, MJ, Qiu, Y, Yang, WH, Cerione, RA (January 2022) Rho GTPases. In: Encyclopedia of Cell Biology: Volume 1-6, Second Edition. UNSPECIFIED, pp. 260-271. ISBN 9780128216248

Lukey, M. J., Cerione, R. A. (August 2015) Rho GTPases. In: Encyclopedia of Cell Biology. Elsevier, pp. 731-740. ISBN 978-0-12-394796-3

Conference or Workshop Item

Ferrer, Miriam, Mourikis, Nicholas, Davidson, Emma E, Kleeman, Sam O, Zaccaria, Marta, Habel, Jill, Rubino, Rachel, Flint, Thomas R, Connell, Claire M, Lukey, Michael J, White, Eileen P, Coll, Anthony P, Venkitaraman, Ashok R, Janowitz, Tobias (2023) Ketogenic diet promotes tumor ferroptosis but induces relative corticosterone deficiency that accelerates cachexia. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023, 2023 Apr 14-19, Orlando, FL.