Items where Community is "Lyons lab"

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Number of items at this level: 54.

Damoci, Chris B, Merrill, Joseph R, Sun, Yanping, Lyons, Scott K, Olive, Kenneth P (March 2024) Addressing Biological Questions with Preclinical Cancer Imaging. Cold Spring Harbor Perspectives in Medicine. a041378-a041378. ISSN 2157-1422

Homer, Joshua A, Koelln, Rebecca A, Barrow, Andrew S, Gialelis, Timothy L, Boiarska, Zlata, Steinohrt, Nikita S, Lee, Erinna F, Yang, Wen-Hsuan, Johnson, Robert M, Chung, Taemoon, Habowski, Amber N, Vishwakarma, Dharmendra S, Bhunia, Debmalya, Avanzi, Charlotte, Moorhouse, Adam D, Jackson, Mary, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Fairlie, W Douglas, Haider, Shozeb M, Steinmetz, Michel O, Prota, Andrea E, Moses, John E (March 2024) Modular synthesis of functional libraries by accelerated SuFEx click chemistry. Chemical Science, 15 (11). pp. 3879-3892. ISSN 2041-6520 (Public Dataset)

Chung, Taemoon, Merrill, Joseph R, Lyons, Scott K (2024) CRISPR/Cas for PET Reporter Gene Engineering. In: Methods in Molecular Biology. UNSPECIFIED, pp. 285-301. ISBN 9781071634981

Merrill, Joseph R, Inguscio, Alessandra, Chung, Taemoon, Demestichas, Breanna, Garcia, Libia A, Habel, Jill, Lewis, David Y, Janowitz, Tobias, Lyons, Scott K (August 2023) Sensitive, non-immunogenic in vivo imaging of cancer metastases and immunotherapy response. Cell Stress, 7 (8). pp. 59-68. ISSN 2523-0204

Lyon, Gholson J, Longo, Joseph, Garcia, Andrew, Inusa, Fatima, Marchi, Elaine, Shi, Daniel, Dörfel, Max, Arnesen, Thomas, Aldabe, Rafael, Lyons, Scott, Nashat, Melissa, Bolton, David (April 2023) Evaluating possible maternal effect lethality of Naa10 knockout mice, and modulation of phenotypes for embryonic and neonatal lethality by genetic background and environment. (Submitted)

Gialelis, Timothy L, Wang, Zifei, Homer, Joshua A, Yang, Wen-Hsuan, Chung, Taemoon, Hu, Qingting, Smedley, Christopher J, Pawar, Nitin J, Upadhyay, Nitinkumar S, Tuveson, David A, Lyons, Scott K, Lukey, Michael J, Moses, John E (April 2023) Inhibition of mitochondrial metabolism by (-)-jerantinine A: synthesis and biological studies in triple-negative breast cancer cells. MedChemComm, 14 (4). pp. 710-714. ISSN 2632-8682

Chung, Taemoon, Garcia, Libia, Swamynathan, Manojit M, Froeling, Fieke EM, Trotman, Lloyd C, Tuveson, David A, Lyons, Scott K (April 2023) Internally Controlled and Dynamic Optical Measures of Functional Tumor Biology. Analytical Chemistry, 95 (13). pp. 5661-5670. ISSN 0003-2700

Demyan, Lyudmyla, Standring, Oliver, Chung, Taemoon, Gazzara, Emma, Lyons, Scott, Park, Youngkyu, King, Daniel, Jonas, Oliver, Tuveson, David, Weiss, Matthew (2023) Feasibility of Implantable Microdosing Devices to Perform in vivo Pharmacotyping in Pancreatic Cancer. In: Annual International Conference of the Society-of-Surgical-Oncology (SSO) on Surgical Cancer Care, MAR 22-25, 2023, Boston, MA.

Dzien, Piotr, Mackintosh, Agata, Malviya, Gaurav, Johnson, Emma, Soloviev, Dmitry, Brown, Gavin, Uribe, Alejandro Huerta, Nixon, Colin, Lyons, Scott K, Maddocks, Oliver, Blyth, Karen, Lewis, David Y (2023) Positron emission tomography imaging of the sodium iodide symporter senses real-time energy stress in vivo. Cancer & Metabolism, 11 (1). ISSN 2049-3002

Katcher, Arielle, Chung, Charlie, Gorman, Megan, Yueh, Brian, Lyons, Scott, Merrill, Joseph, Garcia, Libia, Frimer, Marina, Goldberg, Gary L, Beyaz, Semir (2023) A clinically-relevant orthotopic endometrial carcinosarcoma mouse model using human patient-derived organoids. In: American Association for Cancer Research Annual Meeting 2023, 2023 Apr 14-19, Orlando, FL.

Sun, Xueqin, Klingbeil, Olaf, Lu, Bin, Wu, Caizhi, Ballon, Carlos, Ouyang, Meng, Wu, Xiaoli S, Jin, Ying, Hwangbo, Yon, Huang, Yu-Han, Somerville, Tim DD, Chang, Kenneth, Park, Jung, Chung, Taemoon, Lyons, Scott K, Shi, Junwei, Vogel, Hannes, Schulder, Michael, Vakoc, Christopher R, Mills, Alea A (December 2022) BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network. Nature. ISSN 0028-0836

Hazra, Rasmani, Brine, Lily, Garcia, Libia, Benz, Brian, Chirathivat, Napon, Shen, Michael M, Wilkinson, John Erby, Lyons, Scott K, Spector, David L (November 2022) Platr4 is an early embryonic lncRNA that exerts its function downstream on cardiogenic mesodermal lineage commitment. Developmental Cell, 57 (21). 2450-2468.e7. ISSN 1534-5807

Song, Dongyan, Adrover, Jose M, Felice, Christy, Christensen, Lisa N, He, Xue-Yan, Merrill, Joseph R, Wilkinson, John E, Janowitz, Tobias, Lyons, Scott K, Egeblad, Mikala, Tonks, Nicholas K (July 2022) PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils. JCI Insight, 7 (14). e158199. ISSN 2379-3708

Chung, Taemoon, Garcia, Libia, Swamynathan, Manojit M, Froeling, Fieke EM, Trotman, Lloyd C, Tuveson, David A, Lyons, Scott K (May 2022) Internally-controlled and dynamic optical measures of functional tumor biology. biorxiv.

Adrover, Jose M, Carrau, Lucia, Daßler-Plenker, Juliane, Bram, Yaron, Chandar, Vasuretha, Houghton, Sean, Redmond, David, Merrill, Joseph R, Shevik, Margaret, tenOever, Benjamin R, Lyons, Scott K, Schwartz, Robert E, Egeblad, Mikala (February 2022) Disulfiram inhibits neutrophil extracellular trap formation protecting rodents from acute lung injury and SARS-CoV-2 infection. JCI Insight. ISSN 2379-3708

Safaric Tepes, Polona, Segovia, Danilo, Jevtic, Sania, Ramirez, Daniel, Lyons, Scott K, Sordella, Raffaella (November 2021) Patient-derived xenografts and in vitro model show rationale for imatinib mesylate repurposing in HEY1-NCoA2-driven mesenchymal chondrosarcoma. Laboratory Investigation. ISSN 0023-6837

Lyons, S. K., Francis, K. P., Contag, C. H. (August 2021) Functional Imaging Using Bioluminescent Reporter Genes in Living Subjects. In: Molecular Imaging (Second Edition). Academic Press, pp. 113-141. ISBN 9780128163870

Kweon, Hyae Yon, Lee, Mi-Ni, Dorfel, Max, Seo, Seungwoon, Gottlieb, Leah, PaPazyan, Thomas, McTiernan, Nina, Ree, Rasmus, Bolton, David, Garcia, Andrew, Flory, Michael, Crain, Jonathan, Sebold, Alison, Lyons, Scott, Ismail, Ahmed, Marchi, Elaine, Sonn, Seong-Keun, Jeong, Se-Jin, Jeon, Sejin, Ju, Shinyeong, Conway, Simon J, Kim, Taesoo, Kim, Hyun-Seok, Lee, Cheolju, Roh, Tae-Young, Arnesen, Thomas, Marmorstein, Ronen, Oh, Gootaeg, Lyon, Gholson J (August 2021) Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway. eLife, 10. ISSN 2050-084X

Lyons, Scott K, Plenker, Dennis, Trotman, Lloyd C (July 2021) Advances in preclinical evaluation of experimental antibody-drug conjugates. Cancer Drug Resistance, 4. pp. 745-754. ISSN 2578-532X

Oni, Tobiloba E, Bautista, Carmelita, Merrill, Joseph R, Goos, Jeroen ACM, Rivera, Keith D, Miyabayashi, Koji, Biffi, Giulia, Garcia, Libia, Plenker, Dennis, Patel, Hardik, Elyada, Ela, Samaritano, Maria, Yu, Kenneth H, Pappin, Darryl J, Goggins, Michael G, Hruban, Ralph H, Lewis, Jason S, Lyons, Scott K, Yeh, Johannes T, Tuveson, David A (September 2020) Detection of incipient pancreatic cancer with novel tumor-specific antibodies in mouse models. BioRxiv. (Unpublished)

Lenos, K. J., Lodestijn, S. C., Lyons, S. K., Bijlsma, M. F., Miedema, D. M., Vermeulen, L. (August 2019) A marker-independent lineage-tracing system to quantify clonal dynamics and stem cell functionality in cancer tissue. Nat Protoc, 14 (9). pp. 2648-2671. ISSN 1750-2799

Albrengues, J., Shields, M. A., Ng, D., Park, C. G., Ambrico, A., Poindexter, M. E., Upadhyay, P., Uyeminami, D. L., Pommier, A., Kuttner, V., Bruzas, E., Maiorino, L., Bautista, C., Carmona, E. M., Gimotty, P. A., Fearon, D. T., Chang, K., Lyons, S. K., Pinkerton, K. E., Trotman, L. C., Goldberg, M. S., Yeh, J. T., Egeblad, M. (September 2018) Neutrophil extracellular traps produced during inflammation awaken dormant cancer cells in mice. Science, 361 (6409). ISSN 0036-8075

Lenos, K. J., Miedema, D. M., Lodestijn, S. C., Nijman, L. E., van den Bosch, T., Romero Ros, X., Lourenco, F. C., Lecca, M. C., van der Heijden, M., van Neerven, S. M., van Oort, A., Leveille, N., Adam, R. S., de Sousa, E. Melo F., Otten, J., Veerman, P., Hypolite, G., Koens, L., Lyons, S. K., Stassi, G., Winton, D. J., Medema, J. P., Morrissey, E., Bijlsma, M. F., Vermeulen, L. (September 2018) Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer. Nat Cell Biol, 20 (10). pp. 1193-1202. ISSN 1465-7392

Pommier, A., Anaparthy, N., Memos, N., Kelley, Z. L., Gouronnec, A., Yan, R., Auffray, C., Albrengues, J., Egeblad, M., Iacobuzio-Donahue, C. A., Lyons, S. K., Fearon, D. T. (May 2018) Unresolved endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases. Science, 360 (394). ISSN 0036-8075

English, W. R., Lunt, S. J., Fisher, M., Lefley, D. V., Dhingra, M., Lee, Y. C., Bingham, K., Hurrell, J. E., Lyons, S. K., Kanthou, C., Tozer, G. M. (May 2017) Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma. Cancer Res, 77 (10). pp. 2633-2646. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Koh, S. B., Mascalchi, P., Rodriguez, E., Lin, Y., Jodrell, D. I., Richards, F. M., Lyons, S. K. (January 2017) A quantitative FastFUCCI assay defines cell cycle dynamics at a single-cell level. J Cell Sci, 130 (2). pp. 512-520. ISSN 0021-9533

Pommier, Arnaud, Anaparthy, Naishitha, Memos, Nicoletta, Kelley, Larkin, Gouronnec, Alizée, Albrengues, Jean, Egeblad, Mikala, Iacobuzio-Donahue, Christine, Lyons, Scott, Fearon, Douglas (2017) Endoplasmic reticulum stress engenders immune-resistant, latent pancreatic cancer metastases. Science. (Submitted)

Goldie, S. J., Lyons, S. K. (November 2016) Irrigation of cutaneous squamous cell carcinoma wounds to prevent local recurrence. J Plast Reconstr Aesthet Surg, 69 (11). pp. 1565-1568. ISSN 1878-0539 (Electronic)1748-6815 (Linking)

Dzien, P., Tee, S. S., Kettunen, M. I., Lyons, S. K., Larkin, T. J., Timm, K. N., Hu, D. E., Wright, A., Rodrigues, T. B., Serrao, E. M., Marco-Rius, I., Mannion, E., D'Santos, P., Kennedy, B. W., Brindle, K. M. (August 2016) (13) C magnetic resonance spectroscopy measurements with hyperpolarized [1-(13) C] pyruvate can be used to detect the expression of transgenic pyruvate decarboxylase activity in vivo. Magn Reson Med, 76 (2). pp. 391-401. ISSN 1522-2594 (Electronic)0740-3194 (Linking)

Asim, M., Massie, C. E., Orafidiya, F., Pertega-Gomes, N., Warren, A. Y., Esmaeili, M., Selth, L. A., Zecchini, H. I., Luko, K., Qureshi, A., Baridi, A., Menon, S., Madhu, B., Escriu, C., Lyons, S., Vowler, S. L., Zecchini, V. R., Shaw, G., Hessenkemper, W., Russell, R., Mohammed, H., Stefanos, N., Lynch, A. G., Grigorenko, E., D'Santos, C., Taylor, C., Lamb, A., Sriranjan, R., Yang, J., Stark, R., Dehm, S. M., Rennie, P. S., Carroll, J. S., Griffiths, J. R., Tavare, S., Mills, I. G., McEwan, I. J., Baniahmad, A., Tilley, W. D., Neal, D. E. (May 2016) Choline Kinase Alpha as an Androgen Receptor Chaperone and Prostate Cancer Therapeutic Target. J Natl Cancer Inst, 108 (5). ISSN 1460-2105 (Electronic)0027-8874 (Linking)

Lyons, S. K. (May 2015) Imaging Mouse Models of Cancer. Cancer J, 21 (3). pp. 152-164. ISSN 1540-336X (Electronic)1528-9117 (Linking)

Kirschner, K., Samarajiwa, S. A., Cairns, J. M., Menon, S., Perez-Mancera, P. A., Tomimatsu, K., Bermejo-Rodriguez, C., Ito, Y., Chandra, T., Narita, M., Lyons, S. K., Lynch, A. G., Kimura, H., Ohbayashi, T., Tavare, S., Narita, M. (March 2015) Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53. PLoS Genet, 11 (3). e1005053. ISSN 1553-7390

Lyons, S. K. (February 2015) The development and imaging of advanced cancer models. Journal of Nuclear Medicine, 56 (2). p. 25. ISSN 0161-5505

Patrick, P. S., Rodrigues, T. B., Kettunen, M. I., Lyons, S. K., Neves, A. A., Brindle, K. M. (2015) Development of Timd2 as a reporter gene for MRI. Magn Reson Med. ISSN 0740-3194

Patrick, P. S., Lyons, S. K., Rodrigues, T. B., Brindle, K. M. (October 2014) Oatp1 enhances bioluminescence by acting as a plasma membrane transporter for D-luciferin. Mol Imaging Biol, 16 (5). pp. 626-34. ISSN 1860-2002 (Electronic)1536-1632 (Linking)

Rodriguez, E., Mannion, L., D'Santos, P., Griffiths, M., Arends, M. J., Brindle, K. M., Lyons, S. K. (March 2014) Versatile and enhanced tumour modelling in mice via somatic cell transduction. J Pathol, 232 (4). pp. 449-57. ISSN 1096-9896 (Electronic)0022-3417 (Linking)

Patrick, P. S., Hammersley, J., Loizou, L., Kettunen, M. I., Rodrigues, T. B., Hu, D. E., Tee, S. S., Hesketh, R., Lyons, S. K., Soloviev, D., Lewis, D. Y., Aime, S., Fulton, S. M., Brindle, K. M. (January 2014) Dual-modality gene reporter for in vivo imaging. Proc Natl Acad Sci U S A, 111 (1). pp. 415-20. ISSN 1091-6490 (Electronic)0027-8424 (Linking)

Lyons, S. K., Patrick, P. S., Brindle, K. M. (August 2013) Imaging mouse cancer models in vivo using reporter transgenes. Cold Spring Harb Protoc, 2013 (8). pp. 685-99. ISSN 1559-6095 (Electronic)1559-6095 (Linking)

Roberts, E. W., Deonarine, A., Jones, J. O., Denton, A. E., Feig, C., Lyons, S. K., Espeli, M., Kraman, M., McKenna, B., Wells, R. J. B., Zhao, Q., Caballero, O. L., Larder, R., Coll, A. P., O'Rahilly, S., Brindle, K. M., Teichmann, S. A., Tuveson, D. A., Fearon, D. T. (June 2013) Depletion of stromal cells expressing fibroblast activation protein-alpha from skeletal muscle and bone marrow results in cachexia and anemia. Journal of Experimental Medicine, 210 (6). pp. 1137-1151. ISSN 0022-1007

Goldie, S. J., Mulder, K. W., Tan, D. W., Lyons, S. K., Sims, A. H., Watt, F. M. (July 2012) FRMD4A upregulation in human squamous cell carcinoma promotes tumor growth and metastasis and is associated with poor prognosis. Cancer Res, 72 (13). pp. 3424-36. ISSN 1538-7445 (Electronic)0008-5472 (Linking)

Neves, A. A., Stockmann, H., Harmston, R. R., Pryor, H. J., Alam, I. S., Ireland-Zecchini, H., Lewis, D. Y., Lyons, S. K., Leeper, F. J., Brindle, K. M. (August 2011) Imaging sialylated tumor cell glycans in vivo. FASEB J, 25 (8). pp. 2528-37. ISSN 1530-6860 (Electronic)0892-6638 (Linking)

Massie, C. E., Lynch, A., Ramos-Montoya, A., Boren, J., Stark, R., Fazli, L., Warren, A., Scott, H., Madhu, B., Sharma, N., Bon, H., Zecchini, V., Smith, D. M., Denicola, G. M., Mathews, N., Osborne, M., Hadfield, J., Macarthur, S., Adryan, B., Lyons, S. K., Brindle, K. M., Griffiths, J., Gleave, M. E., Rennie, P. S., Neal, D. E., Mills, I. G. (May 2011) The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis. EMBO J, 30 (13). pp. 2719-33. ISSN 1460-2075 (Electronic)0261-4189 (Linking)

O'Neill, K., Lyons, S. K., Gallagher, W. M., Curran, K. M., Byrne, A. T. (February 2010) Bioluminescent imaging: a critical tool in pre-clinical oncology research. J Pathol, 220 (3). pp. 317-27. ISSN 1096-9896 (Electronic)0022-3417 (Linking)

Lyons, Scott K., Brindle, Kevin M. (2010) Molecular Imaging of Cancer and the Implications for Pre-invasive Disease. In: Pre-Invasive Disease: Pathogenesis and Clinical Management. Springer New York, pp. 167-207. ISBN 978-1-4419-6693-3

Zhang, N., Lyons, S., Lim, E., Lassota, P. (August 2009) A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging. Clin Cancer Res, 15 (15). pp. 4915-24. ISSN 1078-0432 (Print)1078-0432 (Linking)

Lyons, S. K. (2008) Bioluminescence Imaging. In: Encyclopedia of Cancer. Springer. ISBN 978-3-540-47648-1

Kemper, E. M., Leenders, W., Kusters, B., Lyons, S., Buckle, T., Heerschap, A., Boogerd, W., Beijnen, J. H., van Tellingen, O. (December 2006) Development of luciferase tagged brain tumour models in mice for chemotherapy intervention studies. Eur J Cancer, 42 (18). pp. 3294-303. ISSN 0959-8049 (Print)0959-8049 (Linking)

Lyons, S. K., Lim, E., Clermont, A. O., Dusich, J., Zhu, L., Campbell, K. D., Coffee, R. J., Grass, D. S., Hunter, J., Purchio, T., Jenkins, D. (May 2006) Noninvasive bioluminescence imaging of normal and spontaneously transformed prostate tissue in mice. Cancer Res, 66 (9). pp. 4701-7. ISSN 0008-5472 (Print)0008-5472 (Linking)

Lyons, S. K. (January 2005) Advances in imaging mouse tumour models in vivo. J Pathol, 205 (2). pp. 194-205. ISSN 0022-3417 (Print)0022-3417 (Linking)

Zeamari, S., Rumping, G., Floot, B., Lyons, S., Stewart, F. A. (March 2004) In vivo bioluminescence imaging of locally disseminated colon carcinoma in rats. Br J Cancer, 90 (6). pp. 1259-64. ISSN 0007-0920 (Print)0007-0920 (Linking)

Lyons, S. K., Meuwissen, R., Krimpenfort, P., Berns, A. (November 2003) The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice. Cancer Res, 63 (21). pp. 7042-6. ISSN 0008-5472 (Print)0008-5472 (Linking)

Vooijs, M., Jonkers, J., Lyons, S., Berns, A. (March 2002) Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice. Cancer Res, 62 (6). pp. 1862-7. ISSN 0008-5472 (Print)0008-5472 (Linking)

Ladomery, M., Lyons, S., Sommerville, J. (October 1997) Xenopus HDm, a maternally expressed histone deacetylase, belongs to an ancient family of acetyl-metabolizing enzymes. Gene, 198 (1-2). pp. 275-80. ISSN 0378-1119 (Print)0378-1119 (Linking)

Lyons, S. K., Clarke, A. R. (1997) Apoptosis and carcinogenesis. Br Med Bull, 53 (3). pp. 554-69. ISSN 0007-1420 (Print)0007-1420 (Linking)

This list was generated on Thu Mar 28 17:40:41 2024 EDT.
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