Imaging Mouse Models of Cancer

Lyons, S. K. (May 2015) Imaging Mouse Models of Cancer. Cancer J, 21 (3). pp. 152-164. ISSN 1540-336X (Electronic)1528-9117 (Linking)

DOI: 10.1097/ppo.0000000000000112


Mouse models of cancer have proven to be an indispensable resource in furthering both our basic knowledge of cancer biology and the translation of new cancer treatments and imaging approaches into the clinic. As mouse models have developed and improved in their ability to model many diverse aspects of the human disease, so too has the need for robust imaging approaches to measure key biological parameters noninvasively. The aim of this review is to provide a brief overview of the various imaging approaches available to researchers today for imaging preclinical cancer models, highlighting their relative strengths and weaknesses. The very nature of modeling cancer in the mouse is also changing, and brief mention will be made on how imaging can maximize the utility of these new, accurate, and genetically versatile models.

Item Type: Paper
Subjects: diseases & disorders > cancer
Investigative techniques and equipment > imaging
organism description > model organism
organism description > animal > mammal > rodent > mouse
CSHL Authors:
Communities: CSHL labs > Lyons lab
CSHL Cancer Center Program > Cancer Genetics
Depositing User: Matt Covey
Date: May 2015
Date Deposited: 10 Jun 2015 14:22
Last Modified: 15 Oct 2015 15:38
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