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Paper

Hicks, B. A., Stein, R., Efrat, S., Grant, S., Hanahan, D., Demetriou, A. A. (December 1991) Transplantation of Beta-Cells from Transgenic Mice into Nude Athymic Diabetic Rats Restores Glucose Regulation. Diabetes Research and Clinical Practice, 14 (3). pp. 157-164. ISSN 0168-8227

Grant, S. G., Seidman, I., Hanahan, D., Bautch, V. L. (September 1991) Early invasiveness characterizes metastatic carcinoid tumors in transgenic mice. Cancer Res, 51 (18). pp. 4917-23. ISSN 0008-5472 (Print)0008-5472 (Linking)

Grant, S. G., Jessee, J., Bloom, F. R., Hanahan, D. (June 1990) Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants. Proc Natl Acad Sci U S A, 87 (12). pp. 4645-9. ISSN 0027-8424 (Print)0027-8424 (Linking)

Efrat, S., Fleischer, N., Hanahan, D. (April 1990) Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cells. Mol Cell Biol, 10 (4). pp. 1779-83. ISSN 0270-7306 (Print)0270-7306 (Linking)

Rindi, G., Efrat, S., Ghatei, M. A., Bloom, S. R., Solcia, E., Hanahan, D., Polak, J. M. (February 1990) Expression of General Neuroendocrine Markers and Hormones in Pancreatic Glucagonomas of Transgenic Mice. Journal of Pathology, 160 (2). A154-A154. ISSN 0022-3417

Grant, S., Jesse, J., Bloom, F., Hanahan, D. (1990) Plasmid Rescue Using Escherichia-Coli Methylation-Restriction Mutants Allows Efficient Cloning of Transgenic Mouse DNA and Implicates DNA Modifications That Correlate with Developmental Timing of Transgene Expression. Journal of Cellular Biochemistry, 44 (S14E). p. 158.

Edwards, R. H., Rutter, W. J., Hanahan, D. (July 1989) Directed Expression of Ngf to Pancreatic Beta-Cells in Transgenic Mice Leads to Selective Hyperinnervation of the Islets. Cell, 58 (1). pp. 161-170. ISSN 0092-8674

Lindgren, V., Sippolathiele, M., Skowronski, J., Wetzel, E., Howley, P. M., Hanahan, D. (July 1989) Specific Chromosomal-Abnormalities Characterize Fibrosarcomas of Bovine Papillomavirus Type-1 Transgenic Mice. Proceedings of the National Academy of Sciences of the United States of America, 86 (13). pp. 5025-5029. ISSN 0027-8424

Hanahan, D., Jolicoeur, C., Alpert, S., Skowronski, J. (June 1989) Alternative Self or Nonself Recognition of an Antigen Expressed in a Rare Cell Type in Transgenic Mice - Implications for Self-Tolerance and Autoimmunity. Cold Spring Harbor Symposia on Quantitative Biology, 54. pp. 821-835. ISSN 0091-7451

Folkman, J., Watson, K., Ingber, D., Hanahan, D. (May 1989) Induction of Angiogenesis During the Transition from Hyperplasia to Neoplasia. Nature, 339 (6219). pp. 58-61. ISSN 0028-0836

Sippolathiele, M., Hanahan, D., Howley, P. M. (March 1989) Cell-Heritable Stages of Tumor Progression in Transgenic Mice Harboring the Bovine Papillomavirus Type-1 Genome. Molecular and Cellular Biology, 9 (3). pp. 925-934. ISSN 0270-7306

Skowronski, J., Alpert, S., Hanahan, D. (January 1989) Factors Modulating Immunological Non-Responsivenes and Autoimmunity in Insulin T Antigen Transgenic Mice. Journal of Cellular Biochemistry , 41 (Supple). p. 286. ISSN 0733-1959

Mbikay, M., Grant, S. G. N., Sirois, F., Tadros, H., Skowronski, J., Lazure, C., Seidah, N. G., Hanahan, D., Chretien, M. (January 1989) Cdna Sequence of Neuro-Endocrine Protein 7b2 Expressed in Beta-Cell Tumors of Transgenic Mice. International Journal of Peptide and Protein Research, 33 (1). pp. 39-45. ISSN 0367-8377

Efrat, S., Hanahan, D. (1989) Evidence for Threshold Effects in Transformation of Pancreatic Beta-Cells by Sv40 T-Antigen in Transgenic Mice. Current Topics in Microbiology and Immunology, 144. pp. 89-95. ISSN 0070-217X

Bautch, V. L., Toda, S., Hassell, J. A., Hanahan, D. (1989) Tissue specificity of oncogene action: endothelial cell tumours in polyoma middle T transgenic mice. IARC Sci Publ (96). pp. 255-66. ISSN 0300-503

Dycaico, M. J., Grant, S. G. N., Felts, K., Nichols, W. S., Geller, S. A., Hager, J. H., Pollard, A. J., Kohler, S. W., Short, H. P., Jirik, F. R., Hanahan, D., Sorge, J. A. (December 1988) Neonatal Hepatitis Induced by Alpha-1-Antitrypsin - a Transgenic Mouse Model. Science, 242 (4884). pp. 1409-1412. ISSN 0036-8075

Efrat, S., Teitelman, G., Anwar, M., Ruggiero, D., Hanahan, D. (September 1988) Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic alpha cells. Neuron, 1 (7). pp. 605-13. ISSN 0896-6273

Holm, R., Varndell, I. M., Power, R. F., Bishop, A. E., Madsen, O. D., Alpert, S., Hanahan, D., Polak, J. M. (September 1988) Ultrastructure and Electron Immunocytochemistry of Insulin-Producing B-Cell Tumors from Transgenic Mice - Comparison with Counterpart Human-Tumors. Ultrastructural Pathology, 12 (5). pp. 547-559. ISSN 0191-3123

Alpert, S., Hanahan, D., Teitelman, G. (April 1988) Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons. Cell, 53 (2). pp. 295-308. ISSN 0092-8674

Raleigh, E. A., Murray, N. E., Revel, H., Blumenthal, R. M., Westaway, D., Reith, A. D., Rigby, P. W. J., Elhai, J., Hanahan, D. (February 1988) Mcra and Mcrb Restriction Phenotypes of Some Escherichia-Coli Strains and Implications for Gene Cloning. Nucleic Acids Research, 16 (4). pp. 1563-1575. ISSN 0305-1048

Teitelman, G., Alpert, S., Hanahan, D. (January 1988) Proliferation, Senescence, and Neoplastic Progression of Beta-Cells in Hyperplasic Pancreatic-Islets. Cell, 52 (1). pp. 97-105. ISSN 0092-8674

Book Section

Alpert, S., Hanahan, D., Bautch, V. L. (1989) Targeted Expression of Viral Genes to Pancreatic Beta Cells in Transgenic Mice. In: Concepts in viral pathogenesis III. Springer-Verlag, New York, pp. 177-186. ISBN 9780387969749

Patent

Hanahan, Douglas (July 1989) Biologically Pure Escherichia-Coli Cell Line Which Is a Deo-R-Negative Mutant and Which Is More Transformation Efficient with Foreign Plasmids Than Deo-R-Positive Escherichia-Coli Cell Lines Processes for Obtaining These Cell Lines Methods of Use Us Patent-4851348. July 25 1989. 4,851,348.