Training the host organism to enhance anti-cancer immunity

Ferrer, Miriam, Janowitz, Tobias (June 2022) Training the host organism to enhance anti-cancer immunity. Cancer Cell. S1535-6108(22)00267. ISSN 1535-6108

DOI: 10.1016/j.ccell.2022.06.003


In this issue of Cancer Cell, Kurz et al. demonstrate in an orthotopic pancreatic cancer model that low-intensity exercise improves tumor control and response to immunotherapy in an IL-15-dependent manner. Combination therapy, IL-15 super-agonist, anti-PD-1 antibody and chemotherapy, strongly reduces tumor growth. Therefore, the study opens rich translational avenues.

Item Type: Paper
Subjects: diseases & disorders > cancer > drugs and therapies > Immunotherapy
diseases & disorders > cancer > cancer types > pancreatic cancer
CSHL Authors:
Communities: CSHL labs > Janowitz lab
SWORD Depositor: CSHL Elements
Depositing User: CSHL Elements
Date: 14 June 2022
Date Deposited: 28 Jun 2022 22:15
Last Modified: 28 Jun 2022 22:15

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