Weil, C., Martienssen, R.
(April 2008)
Epigenetic interactions between transposons and genes: lessons from plants.
Current opinion in genetics & development, 18 (2).
pp. 188-92.
ISSN 0959-437X (Print)0959-437X (Linking)
Abstract
Transposons replicate, increase in copy number and persist in nature by moving, but insertion into genes is generally mutagenic. There is thus a strong selection for transposons that can achieve a balance between their own replication and minimal damage to their host. Epigenetic regulation proves to be a widespread way to achieve this balance, quieting transposition on the one hand, yet reversible on the other. As our understanding of epigenetics improves, the subtleties and the scope of how transposons can affect gene expression, both directly and indirectly, are becoming clearer.
Item Type: |
Paper
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Uncontrolled Keywords: |
Animals
Chromatin genetics
DNA Transposable Elements genetics
Epigenesis Genetic genetics
Gene Amplification genetics
Genome Plant genetics
Humans
Plants genetics |
Subjects: |
bioinformatics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification bioinformatics > genomics and proteomics > genetics & nucleic acid processing bioinformatics > genomics and proteomics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > epigenetics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > epigenetics bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > genes, structure and function organism description > plant bioinformatics > genomics and proteomics > genetics & nucleic acid processing > DNA, RNA structure, function, modification > transposons |
CSHL Authors: |
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Communities: |
CSHL labs > Martienssen lab |
Depositing User: |
Matt Covey
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Date: |
April 2008 |
Date Deposited: |
26 Feb 2013 21:18 |
Last Modified: |
26 Feb 2013 21:18 |
Related URLs: |
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URI: |
https://repository.cshl.edu/id/eprint/27522 |
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